BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 25203

Title: Changing ABRA protein peptide to fit the HLA-DR B1*0301 molecule renders it protection-inducing   PubMed: 15313182

Deposition date: 2014-09-04 Original release date: 2014-10-07

Authors: Salazar, Luz M.; Alba, Martha P.; Curtidor, Hernando; Bermudez, Adriana; Vargas, Luis E.; Rivera, Zuly J.; Patarroyo, Manuel E.

Citation: Salazar, Luz M.; Alba, Martha P.; Curtidor, Hernando; Bermudez, Adriana; Vargas, Luis E.; Rivera, Zuly J.; Patarroyo, Manuel E.. "Changing ABRA protein peptide to fit into HLA-DRB1*0301 molecule renders it protection-inducing"  Biochem. Biophys. Res. Commun. 322, 119-125 (2014).

Assembly members:
entity, polymer, 20 residues, 2502.966 Da.

Natural source:   Common Name: Malaria parasite   Taxonomy ID: 5833   Superkingdom: Eukaryota   Kingdom: not available   Genus/species: Plasmodium falciparum

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
entity: KMNMLKENVDYIQKNQNLFK

Data sets:
Data typeCount
1H chemical shifts144

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1entity1

Entities:

Entity 1, entity 20 residues - 2502.966 Da.

1   LYSMETASNMETLEULYSGLUASNVALASP
2   TYRILEGLNLYSASNGLNASNLEUPHELYS

Samples:

sample_1: entity7 – 10 mM; water 70%; trifluoroethanol 30%

sample_conditions_1: temperature: 295 K; pH: 3.7; pressure: 1 atm

Experiments:

NameSampleSample stateSample conditions
2D DQF-COSYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

InsightII, Accelrys Software Inc. - geometry optimization, refinement

NMR spectrometers:

  • Bruker DRX 600 MHz

Related Database Links:

PDB
EMBL CDO65562
GB AAA29462 AAF37556 AAN36363 ACR10057 ACR10058
REF XP_001350683 XP_012764154
SP P22620 P23745 Q8I5D2