BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 5713

Title: Influence of pH on NMR structure and stability of the human prion protein globular domain

Deposition date: 2003-03-03 Original release date: 2003-05-21

Authors: Calzolai, Luigi; Zahn, Ralph

Citation: Calzolai, Luigi; Zahn, Ralph. "Influence of pH on NMR structure and stability of the human prion protein globular domain"  J. Biol. Chem. ., .-..

Assembly members:
human prion protein, polymer, 112 residues, Formula weight is not available

Natural source:   Common Name: HUMAN   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
human prion protein: GSVVGGLGGYMLGSAMSRPI IHFGSDYEDRYYRENMHRYP NQVYYRPMDEYSNQNNFVHD CVNITIKQHTVTTTTKGENF TETDVKMMERVVEQMCITQY ERESQAYYQRGS

Data sets:
Data typeCount
13C chemical shifts351
15N chemical shifts126
1H chemical shifts763

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1hPrP1

Entities:

Entity 1, hPrP 112 residues - Formula weight is not available

1   GLYSERVALVALGLYGLYLEUGLYGLYTYR
2   METLEUGLYSERALAMETSERARGPROILE
3   ILEHISPHEGLYSERASPTYRGLUASPARG
4   TYRTYRARGGLUASNMETHISARGTYRPRO
5   ASNGLNVALTYRTYRARGPROMETASPGLU
6   TYRSERASNGLNASNASNPHEVALHISASP
7   CYSVALASNILETHRILELYSGLNHISTHR
8   VALTHRTHRTHRTHRLYSGLYGLUASNPHE
9   THRGLUTHRASPVALLYSMETMETGLUARG
10   VALVALGLUGLNMETCYSILETHRGLNTYR
11   GLUARGGLUSERGLNALATYRTYRGLNARG
12   GLYSER

Samples:

sample_1: human prion protein0.8 – 1.3 mM

Ex-cond1: pH: 7.0; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
experiment_1sample_1not availableEx-cond1

Software:

No software information available

NMR spectrometers:

  • unknown unknown 0 MHz

Download simulated HSQC data in one of the following formats:
CSV: Backbone or all simulated shifts
SPARKY: Backbone or all simulated shifts