BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 25011

Title: Cysteine Deleted Protegrin-1 (CDP-1): Anti-bacterial Activity, Outer-Membrane Disruption and Selectivity   PubMed: 24997421

Deposition date: 2014-06-12 Original release date: 2014-07-28

Authors: Mohanram, Harini; Bhattacharjya, Surajit

Citation: Mohanram, Harini; Bhattacharjya, Surajit. "Cysteine deleted protegrin-1 (CDP-1): Anti-bacterial activity, outer-membrane disruption and selectivity."  Biochim. Biophys. Acta 1840, 3006-3016 (2014).

Assembly members:
entity, polymer, 11 residues, 1482.817 Da.

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemical synthesis   Host organism: Escherichia coli

Entity Sequences (FASTA):
entity: RLYRRRFVVGR

Data sets:
Data typeCount
1H chemical shifts57

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Cysteine Deleted Protegrin-1 (CDP-1): rr111

Entities:

Entity 1, Cysteine Deleted Protegrin-1 (CDP-1): rr11 11 residues - 1482.817 Da.

1   ARGLEUTYRARGARGARGPHEVALVALGLY
2   ARG

Samples:

sample_1: Cysteine Deleted Protegrin-1 (CDP-1): rr11 55.1 mM; H2O 90%; D2O 10%

sample_conditions_1: temperature: 278 K; pH: 4.5; pressure: 1 atm; ionic strength: 55.1 mM

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

SPARKY, Goddard - chemical shift assignment

NMR spectrometers:

  • Bruker DRX 600 MHz