BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 25190

Title: Protection against experimental P. falciparum malaria is associated with short AMA-1 peptide analogue alpha-helical structures   PubMed: 12628294

Deposition date: 2014-09-01 Original release date: 2014-10-07

Authors: Cubillos, Marcia; Salazar, Luz Mary; Torres, Libardo; Patarroyo, Manuel Elkin

Citation: Cubillos, Marcia; Salazar, Luz Mary; Torres, Libardo; Patarroyo, Manuel Elkin. "Protection against experimental P. falciparum malaria is associated with short AMA-1 peptide analogue alpha-helical structures"  Biochemie 84, 1181-1188 (2002).

Assembly members:
entity, polymer, 21 residues, 2271.702 Da.

Natural source:   Common Name: malaria parasite   Taxonomy ID: 5833   Superkingdom: Eukaryota   Kingdom: not available   Genus/species: Plasmodium falciparum

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
entity: MIKSAFLPTGAFKADRYKSH X

Data sets:
Data typeCount
1H chemical shifts134

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1entity1

Entities:

Entity 1, entity 21 residues - 2271.702 Da.

1   METILELYSSERALAPHELEUPROTHRGLY
2   ALAPHELYSALAASPARGTYRLYSSERHIS
3   NH2

Samples:

sample_1: entity 8 mM; water 70%; trifluoroethanol 30%

sample_conditions_1: pH: 3.7; pressure: 1 atm; temperature: 295 K

Experiments:

NameSampleSample stateSample conditions
2D DQF-COSYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

InsightII, Accelrys Software Inc. - geometry optimization, refinement

NMR spectrometers:

  • Bruker DRX 500 MHz

Related Database Links:

PDB
DBJ BAM85358 BAM85359 BAM85360 BAM85361 BAM85362
EMBL CAB66387 CAB97180 CAB97181 CAB97183 CAB97184
GB AAA29475 AAA29476 AAA29718 AAA29719 AAA29720
REF XP_001348015 XP_012763735
SP P22621 P50489 P50490 P50491 P50492