BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 25202

Title: Distorting malaria peptide backbone structure to enable fitting into MHC class II molecules renders modified peptides immunogenic and protective.

Deposition date: 2014-09-04 Original release date: 2014-11-10

Authors: Cifuentes, Gladys; Patarroyo, Manuel; Urquiza, Mauricio; Ramirez, Luis; Reyes, Claudia; Rodriguez, Raul

Citation: Cifuentes, Gladys; Patarroyo, Manuel; Urquiza, Mauricio; Ramirez, Luis; Reyes, Claudia; Rodriguez, Raul. "RESIDUES BELONGING THE N-TERMINAL REGION DERIVED OF MEROZOITE SURFACE PROTEIN-2 OF PLASMODIUM FALCIPARUM"  J. Med. Chem. 46, 2250-2253.

Assembly members:
entity, polymer, 20 residues, 2397.662 Da.

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
entity: KNESKYSNTFINNAYNMSIR

Data sets:
Data typeCount
1H chemical shifts136

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1entity1

Entities:

Entity 1, entity 20 residues - 2397.662 Da.

1   LYSASNGLUSERLYSTYRSERASNTHRPHE
2   ILEASNASNALATYRASNMETSERILEARG

Samples:

sample_1: entity 8 mM; trifluoroethanol 30%; water 70%

sample_conditions_1: temperature: 295 K; pH: 3.7; pressure: 1 atm

Experiments:

NameSampleSample stateSample conditions
2D DQF-COSYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

InsightII, Accelrys Software Inc. - geometry optimization, processing

NMR spectrometers:

  • Bruker DRX 500 MHz

Related Database Links:

BMRB 15075 15590
PDB
EMBL CAA37829 CAA37830 CAA53701 CAA53946 CAA60699
GB AAA19735 AAA19737 AAA19738 AAA19739 AAA19740
PIR B45632 C39112
PRF 2023165A 2023165B
REF XP_001349578
SP P19260 P19599 P50496 P50497 P50498