BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 4266

Title: The Solution Structure of a Superpotent B-chain-shortened Single-replacement Insulin Analogue

Authors: Kurapkat, Guenther; Siedentop, Michael; Gattner, Hans-Georg; Hagelstein, Michael; Brandenburg, Dietrich; Grotzinger, Joachim; Wollmer, Axel

Citation: Kurapkat, Guenther; Siedentop, Michael; Gattner, Hans-Georg; Hagelstein, Michael; Brandenburg, Dietrich; Grotzinger, Joachim; Wollmer, Axel. "The Solution Structure of a Superpotent B-chain-shortend Single-replacement Insulin Analogue"  Protein Sci. 8, 499-508 (1999).

Assembly members:
[D-AlaB26]destetra(B27-B30)insulin-B26-amide, polymer, 47 residues, Formula weight is not available

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemically synthesized

Entity Sequences (FASTA):
[D-AlaB26]destetra(B27-B30)insulin-B26-amide: GIVEQCCTSICSLYQLENYC NFVNQHLCGSHLVEALYLVC GERGFFA

Data sets:
Data typeCount
1H chemical shifts293

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1[D-AlaB26]DTI-amide_A-chain1
2[D-AlaB26]DTI-amide_B-chain1

Entities:

Entity 1, [D-AlaB26]DTI-amide_A-chain 47 residues - Formula weight is not available

1   GLYILEVALGLUGLNCYSCYSTHRSERILE
2   CYSSERLEUTYRGLNLEUGLUASNTYRCYS
3   ASNPHEVALASNGLNHISLEUCYSGLYSER
4   HISLEUVALGLUALALEUTYRLEUVALCYS
5   GLYGLUARGGLYPHEPHEALA

Samples:

sample_one: [D-AlaB26]destetra(B27-B30)insulin-B26-amide 4 mM

sample_conditions_one: pH*: 1.9 na; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions

Software:

No software information available

NMR spectrometers:

  • unknown unknown 0 MHz

Related Database Links:

BMRB 1015 1021 1025 1444 1633
PDB
EMBL CAA08766
GB AAA72171 AAA72917 AAB25817 AAI48489 AAI53084
PRF 0510475A 550086A 560164A 580107B 600165A
REF NP_001035835 XP_004050477 XP_006766071 XP_008576869 XP_008697844
SP F8WCM5