==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=24-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 08-JUL-92 1ADS . COMPND 2 MOLECULE: ALDOSE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.K.WILSON,F.A.QUIOCHO . 315 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13454.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 203 64.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 34 10.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 10 3.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 14 4.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 42 13.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 85 27.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 3 1 2 0 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A A 0 0 129 0, 0.0 13,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-171.6 14.1 45.3 84.4 2 2 A S + 0 0 47 11,-0.1 12,-3.3 12,-0.1 13,-0.4 0.213 360.0 76.5 -69.1 19.6 14.3 41.7 83.1 3 3 A R E -A 13 0A 137 10,-0.3 2,-0.4 11,-0.1 8,-0.0 -0.991 62.5-156.7-141.9 143.9 11.6 42.9 80.5 4 4 A L E -A 12 0A 31 8,-2.5 8,-3.2 -2,-0.4 2,-0.3 -0.921 29.6-115.7-112.9 138.6 11.5 44.9 77.4 5 5 A L E -A 11 0A 111 -2,-0.4 6,-0.2 6,-0.2 2,-0.2 -0.583 27.9-149.2 -79.5 130.0 8.3 46.5 76.2 6 6 A L > - 0 0 7 4,-3.2 3,-2.2 -2,-0.3 198,-0.1 -0.597 28.4-106.5 -94.0 165.2 6.8 45.3 72.9 7 7 A N T 3 S+ 0 0 78 1,-0.3 171,-0.1 196,-0.3 -1,-0.1 0.628 118.9 59.6 -71.6 -8.4 4.8 47.4 70.4 8 8 A N T 3 S- 0 0 63 2,-0.1 -1,-0.3 169,-0.0 3,-0.1 0.295 122.1-103.1 -96.9 8.7 1.6 45.6 71.4 9 9 A G S < S+ 0 0 55 -3,-2.2 -2,-0.1 1,-0.3 2,-0.1 0.328 83.2 123.2 90.0 -11.7 2.0 46.8 75.1 10 10 A A - 0 0 24 144,-0.1 -4,-3.2 95,-0.1 2,-0.5 -0.453 58.5-129.2 -82.7 157.1 3.3 43.4 76.4 11 11 A K E -A 5 0A 108 -6,-0.2 -6,-0.2 -2,-0.1 -1,-0.0 -0.938 16.9-153.1-110.0 129.0 6.5 43.0 78.3 12 12 A M E -A 4 0A 2 -8,-3.2 -8,-2.5 -2,-0.5 2,-0.1 -0.896 22.8-115.2-102.9 125.4 9.0 40.3 77.1 13 13 A P E -A 3 0A 8 0, 0.0 -10,-0.3 0, 0.0 -11,-0.1 -0.360 20.1-139.5 -54.3 128.6 11.5 38.7 79.6 14 14 A I S S+ 0 0 14 -12,-3.3 245,-2.7 244,-0.1 2,-0.4 0.668 88.0 53.9 -70.8 -19.2 15.0 39.7 78.4 15 15 A L B +b 259 0B 6 -13,-0.4 25,-0.5 243,-0.2 26,-0.3 -0.967 68.4 167.6-116.8 131.6 16.3 36.2 79.2 16 16 A G - 0 0 0 243,-2.2 2,-0.5 -2,-0.4 26,-0.2 -0.910 35.5-110.9-135.1 167.1 14.6 33.0 77.8 17 17 A L E -c 42 0B 2 24,-2.3 26,-2.7 -2,-0.3 245,-0.2 -0.890 28.9-143.6 -99.6 124.9 15.5 29.3 77.5 18 18 A G E -cd 43 262B 6 243,-2.2 245,-0.7 -2,-0.5 26,-0.1 -0.507 12.7-170.6 -83.7 156.4 16.2 27.9 74.0 19 19 A T > + 0 0 0 24,-0.6 3,-1.9 -2,-0.2 2,-0.4 0.278 36.9 128.9-132.2 13.3 15.0 24.4 73.1 20 20 A W T 3 S+ 0 0 65 1,-0.3 -2,-0.1 23,-0.1 28,-0.0 -0.591 88.1 8.6 -76.2 127.5 16.6 23.6 69.7 21 21 A K T 3 S+ 0 0 53 -2,-0.4 -1,-0.3 1,-0.3 28,-0.0 0.513 90.5 139.7 81.6 9.1 18.4 20.3 69.9 22 22 A S < - 0 0 4 -3,-1.9 -1,-0.3 241,-0.1 5,-0.1 -0.758 56.0-125.5 -81.3 116.0 16.9 19.6 73.4 23 23 A P >> - 0 0 52 0, 0.0 4,-2.4 0, 0.0 3,-2.3 -0.337 11.6-122.1 -66.9 147.1 16.0 15.9 73.2 24 24 A P H 3> S+ 0 0 64 0, 0.0 4,-0.8 0, 0.0 26,-0.0 0.878 113.5 57.1 -52.7 -39.1 12.3 15.0 74.0 25 25 A G H 34 S+ 0 0 78 1,-0.2 4,-0.2 2,-0.1 25,-0.0 0.620 118.8 28.4 -68.3 -18.0 13.5 12.8 76.8 26 26 A Q H <> S+ 0 0 99 -3,-2.3 4,-2.2 2,-0.1 -1,-0.2 0.597 101.9 75.9-118.5 -19.1 15.4 15.7 78.6 27 27 A V H X S+ 0 0 1 -4,-2.4 4,-2.5 2,-0.2 5,-0.2 0.803 87.8 59.6 -74.9 -23.9 13.5 18.9 77.7 28 28 A T H X S+ 0 0 25 -4,-0.8 4,-2.1 2,-0.2 -1,-0.2 0.978 112.0 41.3 -68.2 -46.7 10.6 18.4 80.1 29 29 A E H > S+ 0 0 115 1,-0.2 4,-2.8 2,-0.2 5,-0.3 0.918 113.2 54.8 -61.8 -41.6 13.0 18.3 83.1 30 30 A A H X S+ 0 0 2 -4,-2.2 4,-2.5 1,-0.2 -1,-0.2 0.917 110.0 44.5 -60.4 -43.6 15.0 21.1 81.6 31 31 A V H X S+ 0 0 0 -4,-2.5 4,-2.5 2,-0.2 -1,-0.2 0.885 112.5 53.4 -71.0 -34.5 11.9 23.5 81.3 32 32 A K H X S+ 0 0 19 -4,-2.1 4,-2.4 -5,-0.2 -2,-0.2 0.955 111.6 44.8 -60.8 -47.8 10.7 22.5 84.8 33 33 A V H X S+ 0 0 30 -4,-2.8 4,-2.8 1,-0.2 -2,-0.2 0.911 111.6 53.5 -61.6 -48.8 14.1 23.4 86.3 34 34 A A H X>S+ 0 0 0 -4,-2.5 5,-2.6 -5,-0.3 4,-1.2 0.931 110.1 46.6 -54.5 -45.6 14.2 26.6 84.3 35 35 A I H ><5S+ 0 0 1 -4,-2.5 3,-0.6 3,-0.2 -2,-0.2 0.926 112.6 50.7 -66.1 -40.9 10.8 27.7 85.6 36 36 A D H 3<5S+ 0 0 95 -4,-2.4 -2,-0.2 1,-0.2 -1,-0.2 0.915 108.7 52.4 -59.8 -41.6 11.8 26.8 89.2 37 37 A V H 3<5S- 0 0 48 -4,-2.8 -1,-0.2 -5,-0.1 -2,-0.2 0.724 130.3 -92.1 -67.6 -27.3 15.1 28.9 88.8 38 38 A G T <<5S+ 0 0 25 -4,-1.2 -3,-0.2 -3,-0.6 2,-0.1 0.406 74.2 145.4 130.4 -1.1 13.1 31.9 87.6 39 39 A Y < + 0 0 2 -5,-2.6 -1,-0.3 -6,-0.2 -23,-0.1 -0.487 16.3 174.1 -64.7 138.0 13.0 31.7 83.8 40 40 A R + 0 0 69 -25,-0.5 33,-2.6 -2,-0.1 2,-0.4 0.293 58.1 66.8-126.9 7.3 9.7 33.1 82.5 41 41 A H E - e 0 73B 1 -26,-0.3 -24,-2.3 31,-0.2 2,-0.4 -0.996 56.5-173.8-135.0 128.6 10.3 32.9 78.7 42 42 A I E -ce 17 74B 0 31,-1.8 33,-2.2 -2,-0.4 2,-0.6 -0.984 14.5-147.2-123.4 131.8 10.7 29.7 76.6 43 43 A D E +ce 18 75B 5 -26,-2.7 -24,-0.6 -2,-0.4 2,-0.2 -0.910 30.4 166.9-101.2 123.2 11.7 29.8 72.9 44 44 A C - 0 0 0 31,-2.2 2,-0.3 -2,-0.6 3,-0.1 -0.678 19.2-170.7-129.7 170.9 10.1 26.9 70.9 45 45 A A > > - 0 0 0 -2,-0.2 3,-1.3 31,-0.2 5,-0.5 -0.871 31.8-128.4-163.7 144.8 9.4 25.7 67.3 46 46 A H G > 5S+ 0 0 35 31,-1.0 3,-1.8 -2,-0.3 5,-0.2 0.892 109.0 59.9 -53.6 -44.9 7.5 23.0 65.6 47 47 A V G 3 5S+ 0 0 24 1,-0.3 -1,-0.3 30,-0.3 74,-0.1 0.673 89.1 71.1 -66.7 -13.6 10.6 21.9 63.7 48 48 A Y G < 5S- 0 0 38 -3,-1.3 -1,-0.3 1,-0.1 -2,-0.2 0.642 95.3-142.5 -77.6 -12.2 12.5 21.2 66.9 49 49 A Q T < 5S+ 0 0 141 -3,-1.8 -2,-0.1 -4,-0.3 -3,-0.1 0.776 77.8 87.3 59.4 32.7 10.1 18.1 67.3 50 50 A N >< + 0 0 1 -5,-0.5 4,-2.1 -4,-0.1 5,-0.2 0.209 41.6 112.7-141.8 13.7 9.8 18.5 71.1 51 51 A E H > S+ 0 0 4 -5,-0.2 4,-2.7 -6,-0.2 5,-0.1 0.890 76.9 58.5 -62.8 -30.1 6.9 20.9 71.7 52 52 A N H > S+ 0 0 71 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.936 109.8 43.5 -59.0 -44.4 4.7 18.2 73.3 53 53 A E H > S+ 0 0 51 2,-0.2 4,-1.2 1,-0.2 -1,-0.2 0.825 112.5 51.3 -75.7 -32.9 7.4 17.5 75.9 54 54 A V H X S+ 0 0 0 -4,-2.1 4,-1.9 1,-0.2 3,-0.4 0.936 109.3 52.7 -61.6 -45.8 8.0 21.3 76.5 55 55 A G H X S+ 0 0 0 -4,-2.7 4,-2.3 1,-0.2 -2,-0.2 0.833 101.6 59.6 -61.6 -34.5 4.2 21.5 76.9 56 56 A V H X S+ 0 0 54 -4,-1.6 4,-1.9 1,-0.2 -1,-0.2 0.898 107.6 46.9 -58.6 -41.0 4.2 18.7 79.6 57 57 A A H X S+ 0 0 0 -4,-1.2 4,-2.3 -3,-0.4 -2,-0.2 0.919 110.6 49.3 -69.8 -42.2 6.6 20.9 81.7 58 58 A I H X S+ 0 0 0 -4,-1.9 4,-2.5 1,-0.2 5,-0.2 0.945 112.1 49.9 -64.5 -45.2 4.6 24.1 81.4 59 59 A Q H X S+ 0 0 80 -4,-2.3 4,-2.6 2,-0.2 -1,-0.2 0.896 109.3 51.9 -55.8 -45.6 1.4 22.2 82.4 60 60 A E H X S+ 0 0 54 -4,-1.9 4,-2.0 1,-0.2 -1,-0.2 0.958 113.1 43.1 -57.2 -50.5 3.1 20.7 85.4 61 61 A K H X>S+ 0 0 9 -4,-2.3 5,-1.6 1,-0.2 6,-1.0 0.822 113.6 51.8 -72.0 -31.2 4.3 24.1 86.7 62 62 A L H ><5S+ 0 0 35 -4,-2.5 3,-0.7 -5,-0.2 -1,-0.2 0.910 111.6 47.4 -64.3 -43.0 0.9 25.8 85.9 63 63 A R H 3<5S+ 0 0 143 -4,-2.6 -2,-0.2 1,-0.2 -1,-0.2 0.873 110.0 52.6 -68.5 -35.5 -0.8 23.0 87.9 64 64 A E H 3<5S- 0 0 89 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.597 108.5-127.5 -69.6 -19.4 1.7 23.4 90.8 65 65 A Q T <<5S+ 0 0 154 -3,-0.7 -3,-0.2 -4,-0.5 -2,-0.1 0.661 70.1 132.6 69.9 22.4 0.9 27.1 90.8 66 66 A V S > - 0 0 97 -2,-0.3 3,-1.6 -3,-0.1 4,-0.6 -0.810 32.0-113.0 -98.7 157.5 0.5 31.8 86.4 69 69 A R G >4 S+ 0 0 31 -2,-0.3 3,-1.7 1,-0.3 -1,-0.1 0.888 112.8 62.4 -59.3 -39.6 0.0 31.8 82.6 70 70 A E G 34 S+ 0 0 121 1,-0.3 -1,-0.3 3,-0.1 -3,-0.0 0.715 102.1 51.1 -61.4 -23.2 0.1 35.6 82.4 71 71 A E G <4 S+ 0 0 70 -3,-1.6 2,-0.3 2,-0.0 -1,-0.3 0.613 95.2 85.0 -93.2 -1.9 3.6 35.7 83.7 72 72 A L << - 0 0 2 -3,-1.7 2,-0.5 -4,-0.6 -31,-0.2 -0.693 62.6-157.2 -90.2 148.2 4.9 33.2 81.2 73 73 A F E -e 41 0B 8 -33,-2.6 -31,-1.8 -2,-0.3 2,-0.5 -0.947 14.6-172.0-127.2 103.7 6.0 34.4 77.7 74 74 A I E -e 42 0B 0 -2,-0.5 32,-1.5 -33,-0.2 31,-1.4 -0.872 0.8-169.7-106.0 130.4 5.9 31.5 75.3 75 75 A V E +ef 43 106B 0 -33,-2.2 -31,-2.2 -2,-0.5 2,-0.3 -0.921 10.1 166.7-118.7 134.3 7.3 31.8 71.7 76 76 A S E - f 0 107B 0 30,-1.8 32,-2.4 -2,-0.4 2,-0.4 -0.864 21.6-131.0-136.7-177.8 7.0 29.5 68.8 77 77 A K E - f 0 108B 0 -2,-0.3 -31,-1.0 30,-0.2 2,-0.4 -0.999 13.8-121.9-142.8 143.2 7.6 29.7 65.0 78 78 A L E - f 0 109B 0 30,-2.8 32,-2.0 -2,-0.4 33,-0.4 -0.638 37.5-132.5 -79.7 118.6 5.8 28.9 61.7 79 79 A W > - 0 0 9 -2,-0.4 3,-1.8 31,-0.1 36,-0.1 -0.375 21.0-106.4 -77.3 160.4 8.0 26.5 59.7 80 80 A C G > S+ 0 0 0 1,-0.3 35,-2.4 2,-0.1 3,-0.8 0.685 114.0 62.9 -61.0 -23.0 8.8 27.0 56.0 81 81 A T G 3 S+ 0 0 1 1,-0.2 37,-0.3 33,-0.2 -1,-0.3 0.345 100.6 55.7 -83.3 3.0 6.4 24.3 54.7 82 82 A Y G < + 0 0 50 -3,-1.8 -1,-0.2 35,-0.1 9,-0.1 0.014 67.5 112.5-121.4 25.6 3.4 26.2 56.1 83 83 A H < + 0 0 2 -3,-0.8 60,-0.1 32,-0.3 2,-0.1 0.726 45.7 107.7 -76.6 -16.6 3.8 29.6 54.5 84 84 A E S >> S- 0 0 46 1,-0.1 3,-2.9 -3,-0.1 4,-1.1 -0.411 81.8-119.9 -59.5 135.9 0.6 29.3 52.3 85 85 A K T 34 S+ 0 0 98 1,-0.3 3,-0.5 2,-0.2 4,-0.5 0.826 112.4 52.2 -43.4 -42.1 -2.2 31.5 53.6 86 86 A G T 34 S+ 0 0 76 1,-0.2 -1,-0.3 2,-0.1 4,-0.2 0.534 108.8 48.5 -79.9 -6.7 -4.4 28.5 54.1 87 87 A L T <> S+ 0 0 65 -3,-2.9 4,-2.0 -5,-0.1 -1,-0.2 0.635 87.0 83.6-104.9 -14.9 -1.9 26.5 56.2 88 88 A V H X S+ 0 0 1 -4,-1.1 4,-2.2 -3,-0.5 5,-0.2 0.918 91.6 47.3 -59.0 -47.5 -0.8 29.1 58.8 89 89 A K H > S+ 0 0 68 -4,-0.5 4,-3.0 1,-0.2 -1,-0.2 0.916 111.1 51.1 -62.1 -44.9 -3.7 28.7 61.2 90 90 A G H > S+ 0 0 41 -4,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.872 109.2 50.8 -59.4 -40.5 -3.4 24.9 61.2 91 91 A A H X S+ 0 0 9 -4,-2.0 4,-1.9 2,-0.2 -2,-0.2 0.912 112.2 47.6 -65.2 -41.8 0.4 25.1 62.0 92 92 A C H X S+ 0 0 0 -4,-2.2 4,-2.7 2,-0.2 -2,-0.2 0.940 111.0 50.1 -65.9 -44.8 -0.4 27.5 64.9 93 93 A Q H X S+ 0 0 86 -4,-3.0 4,-2.5 1,-0.2 -1,-0.2 0.864 108.1 54.1 -64.4 -36.5 -3.2 25.2 66.3 94 94 A K H X S+ 0 0 99 -4,-2.1 4,-2.3 2,-0.2 -1,-0.2 0.946 110.7 45.9 -61.3 -45.4 -0.9 22.2 66.1 95 95 A T H X S+ 0 0 0 -4,-1.9 4,-2.8 2,-0.2 5,-0.3 0.933 111.6 52.2 -63.9 -41.3 1.8 24.1 68.2 96 96 A L H X>S+ 0 0 11 -4,-2.7 5,-2.2 1,-0.2 4,-1.1 0.936 110.6 48.4 -64.9 -37.8 -0.9 25.2 70.6 97 97 A S H <5S+ 0 0 78 -4,-2.5 -1,-0.2 3,-0.2 -2,-0.2 0.916 112.8 46.7 -61.6 -46.6 -2.1 21.6 71.0 98 98 A D H <5S+ 0 0 30 -4,-2.3 -43,-0.2 1,-0.2 -2,-0.2 0.906 117.7 42.2 -66.0 -41.5 1.4 20.3 71.6 99 99 A L H <5S- 0 0 0 -4,-2.8 -1,-0.2 -5,-0.2 -2,-0.2 0.648 106.5-133.0 -79.5 -11.4 2.2 23.1 74.1 100 100 A K T <5 + 0 0 65 -4,-1.1 2,-0.3 -5,-0.3 -3,-0.2 0.909 61.3 128.3 57.0 50.0 -1.2 22.6 75.6 101 101 A L < - 0 0 19 -5,-2.2 -1,-0.2 -6,-0.2 3,-0.1 -0.845 59.5-142.6-124.5 160.9 -1.9 26.4 75.6 102 102 A D S S+ 0 0 125 -2,-0.3 2,-0.3 1,-0.3 -1,-0.1 0.585 85.4 17.7-104.0 -6.5 -4.8 28.4 74.3 103 103 A Y - 0 0 40 -7,-0.1 2,-0.4 3,-0.0 -1,-0.3 -0.988 66.9-134.6-151.3 157.8 -2.7 31.3 73.1 104 104 A L B -k 153 0C 0 48,-2.1 50,-2.4 -2,-0.3 51,-0.4 -0.851 11.0-144.2-104.1 144.0 0.9 32.1 72.2 105 105 A D S S+ 0 0 5 -31,-1.4 2,-0.3 -2,-0.4 -30,-0.2 0.869 88.1 6.9 -75.0 -31.9 2.6 35.3 73.4 106 106 A L E -f 75 0B 1 -32,-1.5 -30,-1.8 48,-0.2 2,-0.4 -0.983 63.0-167.0-150.4 133.9 4.6 35.6 70.2 107 107 A Y E -fg 76 156B 1 48,-1.8 50,-2.1 -2,-0.3 2,-0.3 -0.996 15.5-161.3-126.2 128.1 4.6 33.7 67.0 108 108 A L E -fg 77 157B 0 -32,-2.4 -30,-2.8 -2,-0.4 2,-0.7 -0.820 27.1-123.3-110.0 142.7 7.5 34.1 64.5 109 109 A I E -fg 78 158B 2 48,-1.8 50,-1.3 -2,-0.3 -30,-0.1 -0.809 33.6-148.7 -74.0 119.0 7.9 33.4 60.8 110 110 A H S S- 0 0 16 -32,-2.0 -1,-0.2 -2,-0.7 -31,-0.1 0.853 70.1 -2.2 -65.1 -38.5 10.9 31.1 61.3 111 111 A W - 0 0 17 -33,-0.4 -1,-0.1 2,-0.2 49,-0.1 -0.958 68.0-122.0-145.7 153.1 12.7 31.9 57.9 112 112 A P S S+ 0 0 1 0, 0.0 2,-0.3 0, 0.0 197,-0.1 0.744 86.7 95.6 -70.9 -17.2 11.6 34.2 55.0 113 113 A T - 0 0 0 195,-0.1 2,-0.4 23,-0.0 -2,-0.2 -0.542 63.9-151.6 -79.3 124.4 11.8 31.2 52.6 114 114 A G - 0 0 0 -2,-0.3 19,-2.0 21,-0.3 2,-0.3 -0.802 11.7-163.6 -94.4 139.2 8.6 29.1 51.8 115 115 A F B -L 132 0D 0 -35,-2.4 -32,-0.3 -2,-0.4 3,-0.1 -0.844 37.3 -81.0-113.7 156.4 9.1 25.4 50.9 116 116 A K - 0 0 78 15,-2.7 17,-0.1 -2,-0.3 15,-0.1 -0.313 56.2-103.7 -59.5 136.9 6.5 23.2 49.2 117 117 A P + 0 0 57 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.229 69.5 99.7 -57.0 146.5 4.0 21.8 51.7 118 118 A G S S- 0 0 41 -37,-0.3 -37,-0.1 1,-0.1 -3,-0.0 -0.980 83.0 -71.3 163.0-169.9 4.3 18.2 52.8 119 119 A K S S+ 0 0 145 -2,-0.3 2,-0.4 3,-0.0 -1,-0.1 0.693 101.7 85.8 -88.7 -16.9 5.5 16.1 55.7 120 120 A E - 0 0 135 1,-0.2 -2,-0.0 -3,-0.1 0, 0.0 -0.693 69.4-148.1 -81.4 132.6 9.3 16.6 55.0 121 121 A F S S+ 0 0 30 -2,-0.4 -1,-0.2 1,-0.3 -41,-0.1 0.814 98.0 31.0 -68.7 -29.8 10.6 19.8 56.7 122 122 A F S S- 0 0 79 -3,-0.0 -1,-0.3 -42,-0.0 2,-0.2 -0.818 87.8-157.4-125.4 85.1 13.1 20.2 53.8 123 123 A P - 0 0 2 0, 0.0 8,-2.3 0, 0.0 2,-0.3 -0.504 9.5-149.5 -64.3 133.8 11.4 18.8 50.7 124 124 A L B -M 130 0E 96 6,-0.3 2,-2.3 -2,-0.2 6,-0.2 -0.811 23.5-106.9-113.4 147.9 14.0 17.8 48.0 125 125 A D > - 0 0 79 4,-2.3 2,-2.2 -2,-0.3 3,-0.5 -0.352 60.9 -90.6 -81.2 72.3 13.5 17.8 44.1 126 126 A E T 3 S+ 0 0 194 -2,-2.3 -2,-0.1 1,-0.3 -1,-0.1 -0.583 125.6 26.9 59.6 -81.7 13.2 14.1 43.7 127 127 A S T 3 S- 0 0 92 -2,-2.2 -1,-0.3 -3,-0.0 -3,-0.0 0.887 128.2 -26.1 -55.7-109.0 17.0 14.5 43.2 128 128 A G S < S+ 0 0 50 -3,-0.5 -2,-0.1 -4,-0.2 3,-0.1 0.971 89.8 54.6 -97.4 -69.1 18.7 17.4 44.9 129 129 A N S S- 0 0 36 -4,-0.2 -4,-2.3 -5,-0.2 2,-0.3 -0.109 79.6 -84.8 -79.2 169.1 17.7 20.9 46.1 130 130 A V B -M 124 0E 20 172,-0.7 -6,-0.3 -6,-0.2 -1,-0.1 -0.603 44.0-124.5 -68.8 132.0 15.0 22.2 48.4 131 131 A V - 0 0 36 -8,-2.3 -15,-2.7 -2,-0.3 -1,-0.1 -0.744 28.6-145.4 -83.4 116.1 11.7 22.6 46.6 132 132 A P B -L 115 0D 71 0, 0.0 -17,-0.3 0, 0.0 2,-0.3 -0.287 5.4-130.4 -75.1 155.1 10.4 26.3 47.1 133 133 A S - 0 0 9 -19,-2.0 -19,-0.3 2,-0.1 -17,-0.1 -0.747 17.7-130.1 -92.9 157.8 6.9 27.4 47.4 134 134 A D S S+ 0 0 151 -2,-0.3 -1,-0.1 -19,-0.1 -19,-0.0 0.298 71.7 118.2 -91.2 9.2 5.9 30.4 45.1 135 135 A T - 0 0 8 -20,-0.0 -21,-0.3 1,-0.0 2,-0.3 -0.310 54.6-143.7 -66.1 156.5 4.3 32.2 48.2 136 136 A N > - 0 0 65 -53,-0.1 4,-1.7 1,-0.1 3,-0.4 -0.834 24.5-101.9-119.8 171.0 5.9 35.5 49.2 137 137 A I H > S+ 0 0 2 -2,-0.3 4,-2.6 1,-0.2 5,-0.1 0.852 117.4 53.8 -57.4 -39.5 6.5 37.2 52.5 138 138 A L H > S+ 0 0 52 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.880 105.9 52.4 -70.6 -36.6 3.5 39.6 52.3 139 139 A D H > S+ 0 0 49 -3,-0.4 4,-1.6 2,-0.2 -1,-0.2 0.909 113.0 45.3 -57.1 -47.6 1.0 36.7 51.8 140 140 A T H X S+ 0 0 0 -4,-1.7 4,-2.0 2,-0.2 -2,-0.2 0.901 109.7 54.4 -70.9 -38.5 2.4 35.0 54.8 141 141 A W H X S+ 0 0 0 -4,-2.6 4,-2.5 1,-0.2 -2,-0.2 0.946 106.1 52.9 -61.1 -43.0 2.3 38.2 56.9 142 142 A A H X S+ 0 0 28 -4,-2.3 4,-1.5 1,-0.2 -1,-0.2 0.918 109.2 49.0 -56.6 -40.8 -1.4 38.7 56.1 143 143 A A H X S+ 0 0 2 -4,-1.6 4,-0.9 1,-0.2 -1,-0.2 0.874 110.8 51.1 -66.8 -34.6 -2.1 35.1 57.3 144 144 A M H X S+ 0 0 0 -4,-2.0 4,-0.9 1,-0.2 3,-0.5 0.888 104.5 56.6 -68.4 -40.4 -0.1 35.9 60.5 145 145 A E H >X S+ 0 0 14 -4,-2.5 4,-1.7 1,-0.2 3,-0.7 0.878 101.1 59.0 -63.3 -31.2 -2.2 39.1 61.1 146 146 A E H 3X S+ 0 0 95 -4,-1.5 4,-1.7 1,-0.2 -1,-0.2 0.869 97.2 60.4 -64.0 -32.4 -5.4 37.0 61.1 147 147 A L H 3<>S+ 0 0 2 -4,-0.9 5,-1.6 -3,-0.5 6,-1.1 0.833 104.0 49.5 -64.8 -35.4 -4.0 34.9 64.0 148 148 A V H X<5S+ 0 0 30 -4,-0.9 3,-1.7 -3,-0.7 -1,-0.2 0.950 110.6 49.6 -68.1 -47.1 -3.9 38.1 66.2 149 149 A D H 3<5S+ 0 0 90 -4,-1.7 -2,-0.2 1,-0.3 -1,-0.2 0.778 110.2 51.8 -66.1 -21.0 -7.5 39.0 65.2 150 150 A E T 3<5S- 0 0 95 -4,-1.7 -1,-0.3 -5,-0.2 -2,-0.2 0.499 113.2-117.5 -91.8 -2.4 -8.7 35.5 66.1 151 151 A G T < 5S+ 0 0 50 -3,-1.7 -3,-0.2 -4,-0.3 -2,-0.1 0.520 81.8 116.9 82.1 7.5 -7.1 35.5 69.5 152 152 A L S > - 0 0 15 -2,-0.5 4,-2.0 153,-0.1 3,-0.6 -0.366 35.0 -94.8 -79.9 174.0 17.3 41.0 56.4 163 163 A H H 3> S+ 0 0 35 1,-0.3 4,-2.5 2,-0.2 5,-0.1 0.807 123.5 54.0 -66.3 -27.9 16.5 44.7 56.6 164 164 A L H 3> S+ 0 0 76 151,-0.4 4,-2.0 2,-0.2 -1,-0.3 0.844 108.0 49.6 -71.2 -35.2 15.0 44.8 53.1 165 165 A Q H <> S+ 0 0 12 -3,-0.6 4,-1.5 2,-0.2 -2,-0.2 0.895 111.9 48.3 -70.4 -37.6 12.5 42.0 54.0 166 166 A V H >X S+ 0 0 0 -4,-2.0 4,-2.7 2,-0.2 3,-0.5 0.961 111.6 50.4 -62.9 -50.0 11.6 43.9 57.2 167 167 A E H 3X S+ 0 0 57 -4,-2.5 4,-2.0 1,-0.2 -2,-0.2 0.872 104.3 60.0 -58.5 -32.5 11.1 47.1 55.1 168 168 A M H 3< S+ 0 0 76 -4,-2.0 -1,-0.2 2,-0.2 -2,-0.2 0.918 110.3 40.1 -61.6 -44.8 8.9 45.0 52.7 169 169 A I H X< S+ 0 0 0 -4,-1.5 3,-2.2 -3,-0.5 -2,-0.2 0.937 112.2 56.3 -68.1 -45.9 6.5 44.3 55.6 170 170 A L H 3< S+ 0 0 32 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.823 111.8 43.6 -59.9 -27.4 6.7 47.9 57.0 171 171 A N T 3< S+ 0 0 114 -4,-2.0 -1,-0.3 -5,-0.2 -2,-0.2 0.290 82.3 131.8 -99.6 10.0 5.6 49.2 53.6 172 172 A K X - 0 0 34 -3,-2.2 3,-1.8 -5,-0.1 -3,-0.1 -0.450 66.7-110.6 -62.5 125.5 2.8 46.7 53.1 173 173 A P T 3 S+ 0 0 118 0, 0.0 3,-0.1 0, 0.0 -1,-0.1 -0.370 103.1 10.8 -53.2 126.8 -0.4 48.5 52.0 174 174 A G T 3 S- 0 0 71 1,-0.2 -2,-0.1 2,-0.1 -3,-0.1 0.743 84.8-177.4 75.3 18.4 -2.9 48.2 54.8 175 175 A L < + 0 0 45 -3,-1.8 -1,-0.2 1,-0.2 3,-0.1 -0.344 6.4 178.8 -50.8 122.1 -0.4 46.9 57.3 176 176 A K + 0 0 109 1,-0.3 2,-0.5 -3,-0.1 -1,-0.2 0.835 63.6 28.4 -97.8 -45.4 -2.4 46.2 60.4 177 177 A Y S S- 0 0 68 -22,-0.0 -1,-0.3 -169,-0.0 -32,-0.1 -0.979 72.9-142.1-123.2 123.4 0.3 44.8 62.9 178 178 A K - 0 0 113 -2,-0.5 -22,-0.3 -3,-0.1 2,-0.1 -0.547 38.5 -91.3 -73.8 147.9 3.9 45.6 62.8 179 179 A P - 0 0 0 0, 0.0 -22,-0.3 0, 0.0 -1,-0.1 -0.426 35.2-161.8 -54.1 130.0 6.5 42.8 63.6 180 180 A A + 0 0 1 -24,-2.6 25,-2.3 1,-0.2 2,-0.3 0.792 69.0 21.1 -84.0 -32.0 7.1 43.0 67.2 181 181 A V E - i 0 205B 0 -25,-0.4 -23,-2.7 23,-0.2 2,-0.5 -0.986 52.3-160.2-142.8 142.2 10.4 41.1 67.2 182 182 A N E -hi 158 206B 0 23,-2.1 25,-1.7 -2,-0.3 2,-0.6 -0.986 19.8-157.2-119.4 115.3 13.1 40.1 64.7 183 183 A Q E +hi 159 207B 7 -25,-2.4 -23,-2.2 -2,-0.5 2,-0.3 -0.840 25.3 162.1 -95.3 119.2 15.0 37.0 66.1 184 184 A I E - i 0 208B 4 23,-2.6 25,-2.6 -2,-0.6 2,-0.2 -0.921 45.4 -90.9-135.1 159.5 18.5 36.8 64.6 185 185 A E E + i 0 209B 0 -2,-0.3 2,-0.3 23,-0.2 25,-0.2 -0.547 54.1 163.3 -65.3 133.6 21.8 35.1 65.2 186 186 A C + 0 0 2 23,-2.1 5,-0.2 -2,-0.2 27,-0.2 -0.927 9.1 123.0-161.5 131.4 24.1 37.4 67.3 187 187 A H B > S-N 190 0F 4 3,-1.3 3,-2.0 -2,-0.3 25,-0.1 -0.914 75.1 -67.6-167.1 179.1 27.2 36.9 69.4 188 188 A P T 3 S+ 0 0 0 0, 0.0 3,-0.3 0, 0.0 24,-0.0 0.729 131.1 50.8 -57.2 -23.4 30.8 38.4 69.5 189 189 A Y T 3 S+ 0 0 4 1,-0.3 106,-2.3 103,-0.2 104,-1.9 0.521 122.4 28.9 -92.2 -4.1 31.7 36.8 66.1 190 190 A L B < S+N 187 0F 5 -3,-2.0 -3,-1.3 104,-0.2 -1,-0.3 -0.659 72.2 171.7-149.0 81.5 28.6 38.1 64.3 191 191 A T - 0 0 1 -3,-0.3 5,-0.1 -5,-0.2 -2,-0.1 0.671 23.9-152.5 -79.5 -19.3 27.7 41.3 66.1 192 192 A Q > + 0 0 25 1,-0.1 4,-2.7 3,-0.1 5,-0.3 0.735 30.0 162.2 62.6 33.8 25.0 42.5 63.7 193 193 A E H > S+ 0 0 78 1,-0.2 4,-2.5 2,-0.2 5,-0.1 0.877 71.8 44.8 -57.9 -38.7 25.5 46.3 64.4 194 194 A K H > S+ 0 0 95 2,-0.2 4,-2.5 1,-0.2 -1,-0.2 0.906 115.5 44.4 -76.4 -37.6 23.6 47.5 61.2 195 195 A L H > S+ 0 0 7 2,-0.2 4,-2.7 1,-0.2 5,-0.2 0.920 115.5 48.5 -75.2 -37.5 20.7 45.1 61.4 196 196 A I H X S+ 0 0 4 -4,-2.7 4,-2.9 2,-0.2 5,-0.3 0.958 113.0 48.2 -62.8 -48.5 20.2 45.8 65.2 197 197 A Q H X S+ 0 0 124 -4,-2.5 4,-1.8 -5,-0.3 -2,-0.2 0.913 112.9 49.2 -58.1 -43.4 20.5 49.6 64.6 198 198 A Y H X S+ 0 0 25 -4,-2.5 4,-0.7 2,-0.2 -1,-0.2 0.950 115.4 42.5 -59.4 -51.1 17.9 49.3 61.7 199 199 A C H ><>S+ 0 0 0 -4,-2.7 5,-2.3 1,-0.2 3,-1.2 0.939 112.9 50.9 -66.1 -45.2 15.4 47.3 63.8 200 200 A Q H ><5S+ 0 0 82 -4,-2.9 3,-1.3 1,-0.3 -1,-0.2 0.856 106.6 55.3 -61.4 -34.7 15.7 49.3 67.0 201 201 A S H 3<5S+ 0 0 92 -4,-1.8 -1,-0.3 -5,-0.3 -2,-0.2 0.641 107.9 51.1 -70.4 -20.8 15.1 52.5 65.0 202 202 A K T <<5S- 0 0 62 -3,-1.2 -1,-0.3 -4,-0.7 -2,-0.2 0.306 120.6-108.1 -95.1 6.2 11.8 51.0 63.7 203 203 A G T < 5S+ 0 0 49 -3,-1.3 2,-0.5 1,-0.3 -196,-0.3 0.673 74.5 138.9 74.0 17.5 10.6 50.0 67.2 204 204 A I < - 0 0 3 -5,-2.3 -1,-0.3 -6,-0.2 -23,-0.2 -0.836 50.9-132.3 -96.1 126.5 11.2 46.3 66.6 205 205 A V E -i 181 0B 21 -25,-2.3 -23,-2.1 -2,-0.5 2,-0.4 -0.539 18.7-140.2 -75.9 138.1 12.8 44.3 69.5 206 206 A V E -i 182 0B 0 50,-0.4 52,-2.4 -2,-0.2 2,-0.5 -0.887 10.4-161.3-103.6 133.7 15.8 42.1 68.6 207 207 A T E -ij 183 258B 0 -25,-1.7 -23,-2.6 -2,-0.4 2,-0.6 -0.959 13.3-142.4-110.6 128.9 16.3 38.7 70.1 208 208 A A E -ij 184 259B 0 50,-3.1 52,-1.4 -2,-0.5 2,-0.2 -0.810 19.2-170.0 -89.7 115.4 19.8 37.2 69.9 209 209 A Y E +i 185 0B 22 -25,-2.6 -23,-2.1 -2,-0.6 4,-0.1 -0.680 67.3 27.2 -99.2 171.1 19.9 33.5 69.2 210 210 A S S > S+ 0 0 17 50,-0.3 3,-2.0 -2,-0.2 -1,-0.2 0.870 70.6 165.0 45.8 47.9 22.9 31.2 69.4 211 211 A P T 3 S+ 0 0 5 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.754 74.5 46.6 -65.9 -22.9 24.6 33.6 72.0 212 212 A L T 3 S- 0 0 26 -25,-0.1 16,-0.5 -24,-0.0 15,-0.4 0.321 124.6-101.7-100.0 6.8 27.2 31.0 73.0 213 213 A G < - 0 0 4 -3,-2.0 4,-0.2 -27,-0.2 -3,-0.1 0.633 52.7 -94.5 82.5 11.8 28.0 30.1 69.3 214 214 A S > - 0 0 9 1,-0.1 3,-2.2 2,-0.1 -1,-0.2 0.901 47.7-173.5 48.6 62.3 25.9 26.9 69.4 215 215 A P T 3 S+ 0 0 73 0, 0.0 -1,-0.1 0, 0.0 5,-0.1 0.755 82.2 54.1 -59.2 -20.5 28.7 24.4 70.3 216 216 A D T 3 S+ 0 0 66 3,-0.0 -2,-0.1 2,-0.0 4,-0.0 0.268 73.8 133.8 -95.7 9.3 26.1 21.5 69.8 217 217 A R X - 0 0 19 -3,-2.2 3,-1.8 -4,-0.2 81,-0.0 -0.392 62.0-127.4 -58.2 137.1 25.1 22.5 66.2 218 218 A P T 3 S+ 0 0 99 0, 0.0 -1,-0.1 0, 0.0 -197,-0.0 0.841 104.0 55.0 -59.3 -33.4 25.1 19.3 64.1 219 219 A W T 3 S+ 0 0 130 78,-0.1 2,-0.7 2,-0.0 -2,-0.1 0.212 72.2 147.3 -88.1 13.3 27.3 20.7 61.3 220 220 A A < + 0 0 52 -3,-1.8 77,-0.0 1,-0.2 -6,-0.0 -0.416 18.2 123.8 -59.9 98.0 30.0 21.7 63.7 221 221 A K + 0 0 165 -2,-0.7 2,-1.1 3,-0.0 -1,-0.2 0.607 26.5 103.0 -95.7 -74.6 33.1 21.2 61.7 222 222 A P - 0 0 38 0, 0.0 -2,-0.1 0, 0.0 -3,-0.0 -0.184 64.4-146.9 -43.3 -27.2 35.1 24.1 61.5 223 223 A E S S+ 0 0 178 -2,-1.1 3,-0.0 1,-1.0 -3,-0.0 0.963 76.2 72.5 48.4 71.9 37.8 23.2 63.9 224 224 A D + 0 0 100 -3,-0.2 -1,-1.0 1,-0.0 -3,-0.0 -0.727 68.0 48.1 158.9-164.1 37.9 26.6 64.7 225 225 A P + 0 0 7 0, 0.0 2,-0.5 0, 0.0 -2,-0.1 0.731 42.2 166.4 -75.4 143.1 36.0 29.0 66.3 226 226 A S - 0 0 55 1,-0.1 4,-0.3 -3,-0.0 -13,-0.1 -0.987 18.9-163.9-123.2 126.4 34.6 28.5 69.7 227 227 A L S > S+ 0 0 2 -2,-0.5 3,-1.1 -15,-0.4 6,-0.2 0.887 89.9 57.3 -71.8 -39.7 33.3 31.4 71.7 228 228 A L T 3 S+ 0 0 40 -16,-0.5 -1,-0.2 1,-0.3 16,-0.2 0.789 113.7 40.0 -63.8 -24.6 33.3 29.6 75.0 229 229 A E T 3 S+ 0 0 118 15,-0.1 -1,-0.3 4,-0.0 -2,-0.2 0.400 77.7 127.7-104.3 -0.9 37.0 28.9 74.7 230 230 A D X> - 0 0 8 -3,-1.1 4,-2.6 -4,-0.3 3,-0.8 -0.431 54.3-146.0 -62.0 115.8 38.2 32.2 73.3 231 231 A P H 3> S+ 0 0 93 0, 0.0 4,-1.9 0, 0.0 -1,-0.2 0.813 97.4 56.6 -58.1 -29.1 41.1 33.2 75.7 232 232 A R H 3> S+ 0 0 109 2,-0.2 4,-1.1 1,-0.2 -2,-0.1 0.847 110.3 42.5 -72.0 -34.5 40.2 36.9 75.2 233 233 A I H <> S+ 0 0 0 -3,-0.8 4,-2.1 2,-0.2 -1,-0.2 0.875 109.9 57.4 -80.3 -35.6 36.6 36.3 76.4 234 234 A K H X S+ 0 0 83 -4,-2.6 4,-2.5 1,-0.2 -2,-0.2 0.911 104.5 54.7 -53.6 -40.3 37.9 34.0 79.2 235 235 A A H X S+ 0 0 58 -4,-1.9 4,-2.1 2,-0.2 -1,-0.2 0.913 107.2 47.9 -64.1 -41.1 40.0 37.0 80.4 236 236 A I H X S+ 0 0 11 -4,-1.1 4,-1.3 2,-0.2 -1,-0.2 0.925 112.6 49.1 -64.5 -43.4 36.9 39.4 80.6 237 237 A A H X>S+ 0 0 2 -4,-2.1 5,-2.5 2,-0.2 4,-0.6 0.925 109.9 52.5 -62.0 -42.7 34.9 36.8 82.5 238 238 A A H ><5S+ 0 0 66 -4,-2.5 3,-1.1 1,-0.3 -2,-0.2 0.904 104.7 55.3 -60.3 -40.2 37.9 36.2 84.9 239 239 A K H 3<5S+ 0 0 122 -4,-2.1 -1,-0.3 1,-0.3 -2,-0.2 0.832 115.4 39.0 -61.5 -34.2 38.1 39.9 85.7 240 240 A H H 3<5S- 0 0 51 -4,-1.3 -1,-0.3 -3,-0.4 -2,-0.2 0.473 108.6-122.0 -94.9 -1.1 34.4 39.8 86.7 241 241 A N T <<5S+ 0 0 153 -3,-1.1 2,-0.3 -4,-0.6 -3,-0.2 0.873 75.6 119.8 55.4 43.0 34.6 36.4 88.5 242 242 A K < - 0 0 36 -5,-2.5 -1,-0.3 -6,-0.1 2,-0.2 -0.760 69.4-100.7-122.3 169.4 31.9 35.1 86.1 243 243 A T > - 0 0 52 -2,-0.3 4,-2.0 28,-0.1 5,-0.2 -0.582 32.6-110.7 -85.7 164.5 32.0 32.3 83.6 244 244 A T H > S+ 0 0 19 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.907 121.0 54.6 -60.6 -37.6 32.5 32.9 79.8 245 245 A A H > S+ 0 0 12 1,-0.2 4,-1.8 2,-0.2 5,-0.2 0.931 105.9 51.4 -64.3 -41.3 28.9 31.8 79.3 246 246 A Q H > S+ 0 0 16 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.899 110.9 48.0 -62.6 -38.9 27.7 34.4 81.8 247 247 A V H X S+ 0 0 0 -4,-2.0 4,-2.5 1,-0.2 -1,-0.2 0.940 110.9 51.6 -65.1 -42.7 29.6 37.1 80.0 248 248 A L H < S+ 0 0 1 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.772 112.9 44.7 -68.2 -26.2 28.2 36.0 76.6 249 249 A I H X S+ 0 0 0 -4,-1.8 4,-1.2 -5,-0.2 -1,-0.2 0.864 113.3 50.5 -83.4 -37.6 24.7 36.1 77.9 250 250 A R H X S+ 0 0 29 -4,-2.3 4,-2.1 -5,-0.2 -2,-0.2 0.885 98.5 68.7 -67.9 -32.6 25.2 39.5 79.6 251 251 A F H < S+ 0 0 1 -4,-2.5 4,-0.5 1,-0.2 3,-0.3 0.918 102.4 40.7 -55.4 -55.9 26.7 41.1 76.4 252 252 A P H >4>S+ 0 0 5 0, 0.0 5,-2.2 0, 0.0 3,-1.5 0.895 111.0 60.9 -60.9 -34.8 23.4 41.1 74.3 253 253 A M H ><5S+ 0 0 16 -4,-1.2 3,-1.7 1,-0.3 -2,-0.2 0.911 102.2 50.1 -58.0 -42.2 21.4 42.2 77.4 254 254 A Q T 3<5S+ 0 0 52 -4,-2.1 -1,-0.3 -3,-0.3 -3,-0.1 0.586 104.6 57.9 -74.5 -7.1 23.5 45.4 77.6 255 255 A R T < 5S- 0 0 32 -3,-1.5 -1,-0.3 -4,-0.5 -2,-0.2 0.214 123.3-107.1 -97.7 11.7 22.8 46.1 73.9 256 256 A N T < 5S+ 0 0 106 -3,-1.7 -50,-0.4 1,-0.3 2,-0.3 0.841 77.0 138.8 65.7 33.0 19.0 46.0 74.8 257 257 A L < - 0 0 0 -5,-2.2 2,-0.3 -6,-0.1 -1,-0.3 -0.810 56.9-124.6-104.9 149.5 18.6 42.6 73.1 258 258 A V E - j 0 207B 0 -52,-2.4 -50,-3.1 -2,-0.3 2,-0.4 -0.691 32.0-156.9 -81.7 146.8 16.5 39.7 74.4 259 259 A V E -bj 15 208B 0 -245,-2.7 -243,-2.2 -2,-0.3 -50,-0.2 -0.989 15.3-168.2-136.1 138.4 18.8 36.5 74.7 260 260 A I - 0 0 9 -52,-1.4 -50,-0.3 -2,-0.4 -243,-0.1 -0.547 8.9-174.2-127.7 66.8 17.8 32.9 74.6 261 261 A P - 0 0 1 0, 0.0 -243,-2.2 0, 0.0 2,-0.4 -0.348 19.7-136.0 -56.8 138.3 20.7 30.5 75.6 262 262 A K B +d 18 0B 54 -245,-0.2 2,-0.3 -243,-0.0 -243,-0.1 -0.845 34.6 152.0 -98.1 140.4 19.8 26.8 75.3 263 263 A S - 0 0 6 -245,-0.7 -241,-0.1 -2,-0.4 0, 0.0 -0.962 31.1-173.8-158.8 144.9 20.7 24.2 77.9 264 264 A V + 0 0 22 -2,-0.3 -234,-0.1 -234,-0.0 -1,-0.0 0.146 67.1 99.5-112.5 8.0 19.3 20.8 79.1 265 265 A T >> - 0 0 52 1,-0.1 4,-2.7 -235,-0.0 3,-0.6 -0.882 67.9-146.1-101.1 119.0 21.7 20.7 82.0 266 266 A P H 3> S+ 0 0 73 0, 0.0 4,-2.2 0, 0.0 5,-0.2 0.862 98.5 49.2 -53.8 -40.9 20.3 21.8 85.4 267 267 A E H 3> S+ 0 0 167 1,-0.2 4,-2.3 2,-0.2 5,-0.1 0.881 114.9 44.1 -67.3 -34.9 23.6 23.4 86.6 268 268 A R H <> S+ 0 0 151 -3,-0.6 4,-2.9 2,-0.2 -1,-0.2 0.890 109.7 55.4 -78.8 -35.5 24.1 25.3 83.4 269 269 A I H X S+ 0 0 0 -4,-2.7 4,-0.7 1,-0.2 -2,-0.2 0.937 113.9 43.1 -58.9 -42.0 20.4 26.4 83.3 270 270 A A H >X S+ 0 0 40 -4,-2.2 3,-0.9 -5,-0.3 4,-0.7 0.933 113.0 51.2 -69.5 -44.5 21.0 27.8 86.8 271 271 A E H >< S+ 0 0 61 -4,-2.3 3,-1.4 1,-0.2 -2,-0.2 0.930 106.1 55.8 -53.7 -47.4 24.4 29.3 85.9 272 272 A N H 3< S+ 0 0 5 -4,-2.9 -1,-0.2 1,-0.3 -2,-0.2 0.672 100.1 60.2 -63.0 -21.7 22.9 31.1 82.9 273 273 A F H << S+ 0 0 60 -3,-0.9 2,-2.1 -4,-0.7 3,-0.5 0.744 83.4 82.2 -79.2 -23.4 20.3 32.8 85.1 274 274 A K << + 0 0 107 -3,-1.4 -1,-0.2 -4,-0.7 -2,-0.1 -0.366 60.9 102.0 -88.0 66.6 22.9 34.6 87.3 275 275 A V + 0 0 0 -2,-2.1 3,-0.3 -3,-0.1 -1,-0.2 0.229 58.8 72.8-127.9 -0.1 23.4 37.4 84.8 276 276 A F S S+ 0 0 78 -3,-0.5 -2,-0.1 1,-0.2 -3,-0.0 0.606 85.9 68.9 -96.3 -8.9 21.4 40.3 86.4 277 277 A D S S+ 0 0 85 2,-0.0 2,-0.3 0, 0.0 -1,-0.2 0.319 96.7 42.6 -96.1 3.4 23.9 40.9 89.2 278 278 A F - 0 0 22 -3,-0.3 2,-0.4 2,-0.0 -38,-0.0 -0.924 64.5-138.2-145.3 170.2 26.9 42.4 87.3 279 279 A E - 0 0 130 -2,-0.3 2,-0.4 -39,-0.0 -3,-0.0 -0.991 12.7-134.9-136.0 136.3 27.7 44.9 84.5 280 280 A L - 0 0 5 -2,-0.4 -44,-0.0 -30,-0.1 -2,-0.0 -0.747 35.2-121.2 -80.3 137.3 30.2 44.7 81.7 281 281 A S > - 0 0 49 -2,-0.4 4,-2.4 1,-0.1 5,-0.2 -0.274 23.6-105.8 -72.8 171.5 32.1 48.1 81.4 282 282 A S H > S+ 0 0 100 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.898 125.2 54.1 -62.0 -38.3 31.9 50.3 78.2 283 283 A Q H > S+ 0 0 141 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.917 108.2 47.9 -61.1 -47.1 35.5 49.1 77.6 284 284 A D H > S+ 0 0 3 2,-0.2 4,-2.6 1,-0.2 -2,-0.2 0.899 112.7 49.0 -59.4 -44.7 34.4 45.5 77.9 285 285 A M H X S+ 0 0 21 -4,-2.4 4,-2.2 2,-0.2 -2,-0.2 0.932 111.9 47.4 -63.1 -46.0 31.5 46.0 75.5 286 286 A T H X S+ 0 0 98 -4,-2.8 4,-1.5 2,-0.2 -2,-0.2 0.927 112.8 51.0 -64.1 -37.8 33.7 47.8 72.9 287 287 A T H >< S+ 0 0 47 -4,-2.4 3,-0.5 -5,-0.2 4,-0.4 0.956 109.9 48.4 -65.0 -48.5 36.3 45.0 73.1 288 288 A L H >< S+ 0 0 0 -4,-2.6 3,-1.4 1,-0.3 -1,-0.2 0.904 110.0 52.6 -60.2 -36.6 33.6 42.3 72.6 289 289 A L H >< S+ 0 0 39 -4,-2.2 3,-1.3 1,-0.3 -1,-0.3 0.816 99.7 64.3 -68.0 -30.3 32.2 44.2 69.6 290 290 A S T << S+ 0 0 84 -4,-1.5 -1,-0.3 -3,-0.5 -2,-0.2 0.584 87.8 71.3 -71.3 -9.6 35.7 44.3 68.1 291 291 A Y T < + 0 0 25 -3,-1.4 -1,-0.3 -4,-0.4 -2,-0.2 0.440 67.7 131.7 -86.9 3.1 35.8 40.5 67.8 292 292 A N < + 0 0 57 -3,-1.3 -103,-0.2 1,-0.1 -102,-0.2 -0.197 20.6 163.0 -54.8 138.5 33.2 40.4 65.0 293 293 A R - 0 0 107 -104,-1.9 -103,-0.2 2,-0.1 -1,-0.1 0.171 55.9-111.2-141.0 18.1 34.2 38.3 62.1 294 294 A N + 0 0 119 -105,-0.3 2,-0.6 1,-0.2 -104,-0.2 0.843 61.1 159.5 50.4 42.0 30.9 37.8 60.3 295 295 A W - 0 0 48 -106,-2.3 2,-0.4 2,-0.0 -1,-0.2 -0.843 21.8-164.2-102.6 122.9 30.8 34.1 61.2 296 296 A R - 0 0 70 -2,-0.6 3,-0.2 1,-0.1 -106,-0.0 -0.884 19.5-168.4-112.0 126.9 27.4 32.7 61.0 297 297 A V S S+ 0 0 6 -2,-0.4 2,-0.7 1,-0.2 -1,-0.1 0.834 87.0 44.5 -74.4 -44.6 26.4 29.3 62.6 298 298 A C + 0 0 15 1,-0.1 -1,-0.2 2,-0.1 -113,-0.1 -0.844 59.5 147.4-114.7 92.0 23.0 29.2 60.8 299 299 A A - 0 0 16 -2,-0.7 12,-0.2 -3,-0.2 4,-0.1 0.335 52.1-132.0-107.8 3.7 23.3 30.1 57.2 300 300 A L > - 0 0 21 1,-0.1 3,-2.3 2,-0.1 -2,-0.1 0.885 34.3-179.4 47.4 51.3 20.5 27.8 55.7 301 301 A L G > + 0 0 124 1,-0.3 3,-1.1 2,-0.2 -1,-0.1 0.693 67.7 65.6 -60.8 -23.4 23.0 26.7 53.2 302 302 A S G 3 S+ 0 0 66 1,-0.2 -172,-0.7 2,-0.1 -1,-0.3 0.630 104.6 49.1 -72.8 -11.7 20.6 24.4 51.3 303 303 A C G X + 0 0 3 -3,-2.3 3,-2.1 1,-0.1 -1,-0.2 0.121 66.8 121.9-115.5 23.4 18.5 27.4 50.3 304 304 A T T < S+ 0 0 61 -3,-1.1 -1,-0.1 1,-0.3 -2,-0.1 0.688 81.9 45.6 -64.9 -16.0 21.2 29.8 48.9 305 305 A S T 3 S+ 0 0 115 -3,-0.2 -1,-0.3 3,-0.0 -2,-0.1 0.392 83.7 120.6 -98.9 -4.1 19.4 30.0 45.6 306 306 A H S X S- 0 0 16 -3,-2.1 3,-2.3 1,-0.1 -3,-0.1 -0.419 73.7-121.6 -60.2 143.8 15.9 30.4 47.1 307 307 A K T 3 S+ 0 0 119 1,-0.3 -1,-0.1 -2,-0.1 -3,-0.0 0.768 112.2 41.8 -56.3 -23.7 14.3 33.7 45.9 308 308 A D T 3 S+ 0 0 19 -194,-0.1 -1,-0.3 -5,-0.1 -195,-0.1 0.127 74.9 145.2-114.4 18.3 13.9 34.8 49.5 309 309 A Y X - 0 0 22 -3,-2.3 3,-0.6 1,-0.1 -5,-0.1 -0.387 38.9-151.6 -58.0 130.6 17.2 33.7 50.9 310 310 A P G > S+ 0 0 1 0, 0.0 3,-0.6 0, 0.0 -1,-0.1 0.781 75.0 67.4 -86.0 -15.7 18.1 36.4 53.5 311 311 A F G 3 S+ 0 0 40 1,-0.2 -2,-0.1 -12,-0.2 -150,-0.0 0.093 73.8 80.1-105.1 22.3 21.9 36.4 53.6 312 312 A H G < S+ 0 0 133 -3,-0.6 -1,-0.2 3,-0.0 -8,-0.0 0.795 81.4 80.5 -85.0 -36.3 23.0 37.8 50.2 313 313 A E S < S- 0 0 91 -3,-0.6 -150,-0.0 1,-0.1 0, 0.0 -0.293 93.7-115.2 -62.8 154.0 22.3 41.4 51.4 314 314 A E 0 0 145 1,-0.2 -1,-0.1 -152,-0.0 -120,-0.1 0.903 360.0 360.0 -58.6 -42.3 24.9 43.3 53.6 315 315 A F 0 0 52 -121,-0.1 -151,-0.4 -120,-0.1 -1,-0.2 -0.950 360.0 360.0-157.0 360.0 22.3 43.3 56.4