==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=24-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GROWTH FACTOR 13-JUL-93 1AFC . COMPND 2 MOLECULE: ACIDIC FIBROBLAST GROWTH FACTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: BOS TAURUS; . AUTHOR X.ZHU,B.T.HSU,D.C.REES . 1016 8 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 49144.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 659 64.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 310 30.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 15 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 32 3.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 138 13.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 109 10.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 34 3.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 59 15 8 18 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 3 4 9 2 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 10 A K 0 0 126 0, 0.0 36,-0.3 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0 151.9 -6.6 21.5 17.6 2 11 A P - 0 0 58 0, 0.0 2,-0.3 0, 0.0 34,-0.2 -0.578 360.0-175.0 -57.2 157.0 -4.2 20.9 14.7 3 12 A K B -A 35 0A 60 32,-2.3 32,-2.6 -2,-0.3 2,-0.4 -0.733 23.2-139.3-156.6 142.0 -0.8 22.3 14.2 4 13 A L E -E 126 0B 10 122,-2.7 122,-2.6 -2,-0.3 2,-0.5 -0.819 24.4-136.6 -93.9 142.9 1.9 22.4 11.7 5 14 A L E -E 125 0B 3 -2,-0.4 9,-1.1 9,-0.3 2,-0.2 -0.711 19.0-156.4-103.5 102.6 5.4 22.1 13.2 6 15 A Y E -EF 124 13B 68 118,-1.3 118,-1.9 -2,-0.5 2,-0.6 -0.268 3.5-150.7 -86.6 114.2 7.6 24.6 11.4 7 16 A C E > -E 123 0B 0 5,-1.6 4,-1.2 116,-0.3 5,-0.5 -0.819 7.8-146.4 -78.5 134.9 11.2 23.7 11.5 8 17 A S T 4 S+ 0 0 18 114,-2.7 112,-0.2 -2,-0.6 -1,-0.1 0.849 82.1 83.9 -67.5 -39.3 13.5 26.7 11.4 9 18 A N T 4 S- 0 0 44 110,-1.0 -1,-0.2 113,-0.3 111,-0.1 0.872 120.9 -15.1 -28.2 -93.6 16.2 24.7 9.5 10 19 A G T 4 S- 0 0 25 93,-0.3 -1,-0.2 -3,-0.2 -2,-0.2 0.236 99.6 -96.5-104.7 22.7 14.9 25.1 5.9 11 20 A G S < S+ 0 0 16 -4,-1.2 2,-0.3 1,-0.2 -3,-0.1 0.794 76.1 149.6 69.2 46.4 11.4 26.3 6.6 12 21 A Y - 0 0 30 -5,-0.5 -5,-1.6 -6,-0.1 2,-0.3 -0.715 46.4-122.3-107.9 168.8 9.9 22.8 6.3 13 22 A F E -FG 6 25B 13 12,-3.4 12,-1.6 -2,-0.3 2,-0.3 -0.497 30.6-111.8-118.2 120.2 7.0 21.2 7.8 14 23 A L E - G 0 24B 2 -9,-1.1 2,-0.4 -2,-0.3 -9,-0.3 -0.550 42.9-168.3 -42.8 129.9 7.4 17.9 9.8 15 24 A R E - G 0 23B 49 8,-2.5 8,-1.3 -2,-0.3 2,-0.6 -0.945 21.0-164.7-134.9 122.5 5.7 15.3 7.7 16 25 A I E - G 0 22B 0 16,-1.3 6,-0.2 -2,-0.4 36,-0.2 -0.994 21.0-155.8 -99.3 108.5 4.8 11.7 8.6 17 26 A L > - 0 0 32 4,-2.7 3,-2.9 -2,-0.6 4,-0.1 -0.645 27.0-107.9 -86.3 164.7 3.9 9.9 5.4 18 27 A P T 3 S+ 0 0 76 0, 0.0 -1,-0.1 0, 0.0 48,-0.0 0.612 119.0 57.4 -68.1 -21.2 1.7 6.8 5.5 19 28 A D T 3 S- 0 0 121 2,-0.1 47,-0.1 0, 0.0 -2,-0.0 0.414 125.7-103.4 -73.7 -23.7 4.5 4.4 4.8 20 29 A G S < S+ 0 0 11 -3,-2.9 46,-1.1 1,-0.3 2,-0.2 0.664 72.8 142.5 116.2 10.6 6.0 5.9 7.9 21 30 A T - 0 0 65 44,-0.2 -4,-2.7 -4,-0.1 2,-0.4 -0.509 37.2-152.0 -82.0 136.3 8.7 8.1 6.5 22 31 A V E +G 16 0B 6 42,-0.3 2,-0.3 -6,-0.2 -6,-0.2 -0.797 34.5 134.3-113.9 119.8 9.2 11.3 8.3 23 32 A D E -G 15 0B 30 -8,-1.3 -8,-2.5 -2,-0.4 2,-0.3 -0.834 49.2-100.2-147.2-178.2 10.5 14.2 6.4 24 33 A G E -G 14 0B 8 82,-1.6 2,-0.3 -2,-0.3 -10,-0.2 -0.621 28.4-173.0-115.6 144.1 9.8 17.9 5.9 25 34 A T E -G 13 0B 13 -12,-1.6 -12,-3.4 -2,-0.3 5,-0.1 -0.994 22.5-146.6-126.2 156.2 7.9 19.5 3.1 26 35 A K S S+ 0 0 128 -2,-0.3 2,-1.0 -14,-0.2 -1,-0.1 0.472 73.4 100.4-107.8 24.5 7.4 23.2 2.3 27 36 A D - 0 0 88 1,-0.2 3,-0.3 -14,-0.1 6,-0.1 -0.785 52.2-173.1-114.3 73.6 3.9 22.8 0.9 28 37 A R S S+ 0 0 137 -2,-1.0 2,-0.4 1,-0.2 -1,-0.2 0.512 74.5 71.1 -37.6 -29.2 1.9 23.9 3.8 29 38 A S S S+ 0 0 101 4,-0.0 2,-0.3 -3,-0.0 -1,-0.2 -0.354 74.4 121.9 -87.4 38.7 -1.2 22.8 2.1 30 39 A D >> - 0 0 29 -2,-0.4 4,-0.6 -3,-0.3 3,-0.5 -0.784 64.2-131.9-113.3 144.9 -0.6 19.1 2.3 31 40 A Q G >4 S+ 0 0 40 -2,-0.3 3,-0.7 1,-0.2 20,-0.3 0.954 101.1 48.5 -49.8 -42.5 -2.7 16.5 4.0 32 41 A H G 34 S+ 0 0 44 1,-0.2 -16,-1.3 18,-0.1 -1,-0.2 0.124 93.7 71.5 -86.4 -7.4 -0.0 14.8 6.0 33 42 A I G <4 + 0 0 2 -3,-0.5 2,-0.5 -18,-0.2 -1,-0.2 0.782 69.9 106.8 -79.2 -17.5 1.6 17.8 7.6 34 43 A Q << - 0 0 81 -3,-0.7 16,-1.4 -4,-0.6 17,-0.4 -0.045 56.8-170.0 -64.2 120.3 -1.4 18.4 9.9 35 44 A L E -AB 3 49A 0 -32,-2.6 -32,-2.3 -2,-0.5 2,-0.5 -0.693 22.6-163.1-121.3 143.1 -0.2 17.3 13.2 36 45 A Q E - B 0 48A 28 12,-2.7 12,-4.1 -2,-0.4 2,-0.4 -0.933 12.5-177.2-124.1 111.2 -1.9 16.7 16.6 37 46 A L E - B 0 47A 46 -2,-0.5 2,-0.5 -36,-0.3 10,-0.3 -0.903 4.5-167.3-109.9 123.1 0.3 16.5 19.7 38 47 A A - 0 0 62 8,-1.1 8,-0.5 -2,-0.4 -2,-0.0 -0.785 23.5-120.5-111.4 138.7 -1.2 15.7 23.1 39 48 A A + 0 0 80 -2,-0.5 6,-0.2 6,-0.2 3,-0.1 -0.267 27.3 177.9 -81.1 117.2 0.6 16.1 26.5 40 49 A E - 0 0 123 4,-3.0 2,-0.3 0, 0.0 -1,-0.2 0.153 65.6 -7.1 -93.0 -1.7 0.7 12.9 28.2 41 50 A S S S- 0 0 46 3,-0.3 2,-1.7 0, 0.0 3,-0.5 -0.942 104.3 -39.9-169.7-172.3 2.7 14.1 31.2 42 51 A I S S- 0 0 103 -2,-0.3 3,-0.1 1,-0.2 35,-0.0 -0.491 130.6 -17.7 -70.3 89.3 4.5 17.1 32.8 43 52 A G S S+ 0 0 42 -2,-1.7 2,-0.4 1,-0.1 35,-0.3 0.610 110.4 128.8 81.9 35.8 6.4 18.4 29.7 44 53 A E - 0 0 59 -3,-0.5 -4,-3.0 33,-0.2 -3,-0.3 -0.791 38.3-166.5-130.2 119.0 5.8 15.1 27.9 45 54 A V B -J 76 0C 3 31,-1.0 31,-1.7 -2,-0.4 2,-0.4 -0.256 23.0-162.0-110.8 165.7 4.3 15.0 24.4 46 55 A Y - 0 0 46 -8,-0.5 -8,-1.1 29,-0.2 2,-0.5 -0.994 15.3-166.4-141.3 105.8 2.8 12.7 21.7 47 56 A I E +B 37 0A 3 -2,-0.4 9,-2.1 27,-0.4 2,-0.4 -0.990 17.8 174.2 -95.4 137.9 2.8 14.1 18.1 48 57 A K E -BC 36 55A 70 -12,-4.1 -12,-2.7 -2,-0.5 7,-0.2 -0.974 36.1 -98.1-147.9 148.9 0.6 12.2 15.8 49 58 A S E -B 35 0A 0 5,-2.8 -14,-0.1 -2,-0.4 -17,-0.1 -0.096 20.6-158.1 -68.7 133.4 -0.8 12.3 12.3 50 59 A T S S+ 0 0 52 -16,-1.4 -1,-0.1 -19,-0.2 -15,-0.1 0.889 92.5 37.0 -76.0 -30.4 -4.3 13.7 12.0 51 60 A E S S+ 0 0 114 -17,-0.4 -19,-0.1 -20,-0.3 -2,-0.1 0.883 126.3 28.0 -85.8 -68.3 -4.8 12.0 8.7 52 61 A T S S- 0 0 50 -36,-0.2 -1,-0.2 2,-0.1 3,-0.1 0.595 92.5-133.9 -66.0 -33.7 -3.1 8.6 8.8 53 62 A G + 0 0 36 1,-0.3 -2,-0.1 -5,-0.0 14,-0.1 -0.005 60.7 126.0 100.5 -15.8 -3.4 8.1 12.6 54 63 A Q - 0 0 16 -6,-0.1 -5,-2.8 1,-0.1 2,-0.3 -0.183 52.8-113.9 -76.5 173.4 0.2 6.9 13.2 55 64 A F E -CD 48 67A 32 12,-3.8 12,-3.2 -7,-0.2 2,-0.3 -0.641 15.5-112.5-114.0 158.7 2.8 8.3 15.6 56 65 A L E + D 0 66A 1 -9,-2.1 2,-0.3 -2,-0.3 -9,-0.2 -0.437 50.0 167.9 -82.8 110.1 6.1 10.1 15.5 57 66 A A E - D 0 65A 0 8,-2.5 8,-1.8 -2,-0.3 2,-0.4 -0.756 30.3-147.8-122.3 164.0 8.6 7.6 16.9 58 67 A M E - D 0 64A 0 15,-0.9 6,-0.2 -2,-0.3 34,-0.1 -0.934 20.2-144.2-127.0 111.4 12.4 7.3 17.1 59 68 A D > - 0 0 38 4,-1.4 3,-1.5 -2,-0.4 4,-0.0 -0.277 37.9 -88.7 -61.4 177.5 13.9 3.8 16.9 60 69 A T T 3 S+ 0 0 80 1,-0.2 -1,-0.1 2,-0.1 0, 0.0 0.542 125.4 60.7 -75.0 20.5 17.0 2.8 18.8 61 70 A D T 3 S- 0 0 114 2,-0.1 -1,-0.2 50,-0.0 3,-0.1 0.703 119.8-103.9-119.6 -2.1 19.2 4.0 15.9 62 71 A G S < S+ 0 0 0 -3,-1.5 49,-2.1 1,-0.2 2,-0.6 0.400 75.4 137.7 85.9 30.1 18.0 7.5 16.1 63 72 A L B -L 110 0D 79 47,-0.2 -4,-1.4 48,-0.1 -1,-0.2 -0.742 47.8-137.9-114.0 120.8 15.7 7.3 13.0 64 73 A L E +D 58 0A 4 45,-0.6 -42,-0.3 -2,-0.6 2,-0.3 -0.172 34.9 166.2 -80.2 129.9 12.3 9.1 13.3 65 74 A Y E -D 57 0A 53 -8,-1.8 -8,-2.5 -10,-0.1 2,-0.6 -0.891 40.2 -98.9-134.5 172.6 9.6 7.1 11.9 66 75 A G E -D 56 0A 6 -46,-1.1 2,-0.5 -2,-0.3 -10,-0.2 -0.937 38.1-164.6 -99.3 125.0 5.8 6.8 11.8 67 76 A S E -D 55 0A 6 -12,-3.2 -12,-3.8 -2,-0.6 4,-0.0 -0.865 21.4-157.6-112.8 141.0 4.3 4.2 14.2 68 77 A Q S S+ 0 0 157 -2,-0.5 -1,-0.1 -14,-0.2 -48,-0.0 0.506 86.0 56.9 -76.8 -34.7 0.8 2.7 14.2 69 78 A T S S- 0 0 75 -14,-0.1 -1,-0.1 2,-0.0 -2,-0.0 -0.979 88.0-126.3-104.0 116.1 1.1 1.8 17.8 70 79 A P + 0 0 63 0, 0.0 2,-0.3 0, 0.0 3,-0.1 -0.459 50.2 167.7 -52.3 121.8 1.8 4.3 20.4 71 80 A N > - 0 0 53 1,-0.1 3,-2.3 -4,-0.0 4,-0.1 -0.907 56.0 -80.6-141.5 156.7 4.8 2.6 22.0 72 81 A E G > S+ 0 0 70 -2,-0.3 3,-1.0 1,-0.3 20,-0.3 0.867 125.5 64.3 -23.2 -36.3 7.5 3.5 24.5 73 82 A E G 3 S+ 0 0 29 1,-0.2 -15,-0.9 18,-0.1 -1,-0.3 0.354 86.0 74.9 -87.6 34.8 9.3 5.2 21.5 74 83 A C G < + 0 0 1 -3,-2.3 2,-0.7 -17,-0.2 -27,-0.4 0.321 67.8 96.0-122.8 3.3 6.6 7.9 21.0 75 84 A L < + 0 0 15 -3,-1.0 16,-1.0 -4,-0.1 17,-0.4 -0.892 45.1 173.7-110.7 104.7 7.2 10.2 23.9 76 85 A F B -JK 45 90C 0 -31,-1.7 -31,-1.0 -2,-0.7 2,-0.7 -0.838 30.3-123.6 -95.6 146.7 9.3 13.2 23.1 77 86 A L - 0 0 39 12,-1.9 2,-0.3 -2,-0.4 -33,-0.2 -0.866 19.3-135.5-104.6 132.6 9.7 15.8 25.7 78 87 A E + 0 0 68 -2,-0.7 2,-0.4 -35,-0.3 10,-0.2 -0.363 24.1 176.1 -74.9 147.3 8.7 19.4 25.0 79 88 A R E -H 87 0B 44 8,-1.6 8,-1.0 -2,-0.3 2,-0.2 -0.995 22.1-138.6-161.6 102.8 11.0 22.2 25.9 80 89 A L E -H 86 0B 100 -2,-0.4 2,-0.3 6,-0.2 6,-0.2 -0.568 24.9-136.7 -55.9 148.1 10.4 25.8 25.1 81 90 A E > - 0 0 41 4,-1.1 3,-2.3 -2,-0.2 -1,-0.0 -0.714 23.4-105.9-106.5 177.7 13.3 27.9 24.0 82 91 A E T 3 S+ 0 0 97 1,-0.3 2,-0.5 -2,-0.3 -1,-0.1 0.942 125.1 42.5 -67.2 -36.3 14.7 31.2 24.7 83 92 A N T 3 S- 0 0 92 1,-0.1 -1,-0.3 -3,-0.1 3,-0.1 -0.071 122.5-106.3 -91.3 7.9 13.5 32.4 21.3 84 93 A H S < S+ 0 0 133 -3,-2.3 2,-0.3 -2,-0.5 -1,-0.1 0.483 80.2 122.8 72.8 35.0 10.2 30.6 21.7 85 94 A Y - 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