==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-SEP-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 13-APR-97 1AH5 . COMPND 2 MOLECULE: HYDROXYMETHYLBILANE SYNTHASE; . SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI; . AUTHOR J.R.HELLIWELL,Y.P.NIEH,S.J.HARROP,A.CASSETTA . 299 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13156.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 206 68.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 17 5.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 40 13.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 6.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 31 10.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 81 27.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 1 1 1 2 1 0 0 1 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 1 0 0 3 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A D 0 0 146 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 17.4 7.8 19.7 -1.3 2 4 A N + 0 0 85 1,-0.1 31,-2.7 30,-0.1 2,-0.4 0.388 360.0 107.9 62.0 -1.5 11.5 18.9 -1.0 3 5 A V E -a 33 0A 32 29,-0.2 2,-0.4 31,-0.1 31,-0.2 -0.888 46.5-173.5-109.3 133.5 11.4 19.7 2.8 4 6 A L E -a 34 0A 0 29,-2.5 31,-2.5 -2,-0.4 2,-0.5 -0.993 9.2-154.8-127.8 125.4 11.8 16.9 5.4 5 7 A R E -a 35 0A 61 -2,-0.4 58,-2.9 29,-0.2 59,-1.7 -0.885 5.4-154.8-105.9 125.4 11.3 17.6 9.1 6 8 A I E -ab 36 64A 0 29,-3.1 31,-3.4 -2,-0.5 2,-0.4 -0.884 3.2-153.2-103.6 120.1 13.0 15.3 11.7 7 9 A A E +ab 37 65A 0 57,-2.8 59,-1.6 -2,-0.5 2,-0.3 -0.719 29.4 157.5 -89.8 135.9 11.5 15.0 15.2 8 10 A T E -a 38 0A 2 29,-1.5 31,-2.6 -2,-0.4 32,-0.1 -0.971 41.1-102.5-156.3 161.3 14.1 14.1 17.9 9 11 A R - 0 0 51 -2,-0.3 9,-0.1 57,-0.3 57,-0.0 -0.326 35.3-118.7 -76.7 174.1 14.9 14.2 21.6 10 12 A Q S S+ 0 0 97 4,-0.1 -1,-0.1 -2,-0.1 -2,-0.0 0.292 70.9 112.6-105.4 11.8 17.3 16.7 23.0 11 13 A S S > S- 0 0 8 1,-0.1 4,-2.4 128,-0.0 5,-0.2 -0.401 79.3-110.7 -78.7 159.2 20.1 14.6 24.5 12 14 A P H > S+ 0 0 79 0, 0.0 4,-1.9 0, 0.0 5,-0.1 0.915 120.4 48.3 -55.9 -41.5 23.5 14.7 22.9 13 15 A L H > S+ 0 0 35 2,-0.2 4,-2.0 1,-0.2 5,-0.2 0.892 109.8 51.6 -68.5 -37.2 23.1 11.1 21.7 14 16 A A H > S+ 0 0 5 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.916 111.8 46.7 -66.1 -40.8 19.6 11.8 20.3 15 17 A L H X S+ 0 0 51 -4,-2.4 4,-2.0 2,-0.2 -1,-0.2 0.826 107.4 57.8 -70.5 -30.6 20.9 14.8 18.4 16 18 A W H X S+ 0 0 90 -4,-1.9 4,-2.3 -5,-0.2 -2,-0.2 0.956 107.2 47.5 -61.7 -49.5 23.9 12.7 17.1 17 19 A Q H X S+ 0 0 8 -4,-2.0 4,-2.1 1,-0.2 -1,-0.2 0.801 107.6 57.1 -62.4 -30.5 21.4 10.2 15.6 18 20 A A H X S+ 0 0 0 -4,-1.4 4,-2.5 2,-0.2 -1,-0.2 0.938 110.0 43.8 -67.0 -43.3 19.5 13.0 14.1 19 21 A H H X S+ 0 0 86 -4,-2.0 4,-3.3 2,-0.2 5,-0.2 0.891 109.5 56.5 -68.6 -39.2 22.6 14.2 12.2 20 22 A Y H X S+ 0 0 46 -4,-2.3 4,-1.7 2,-0.2 -1,-0.2 0.929 112.0 42.5 -57.1 -47.4 23.6 10.7 11.2 21 23 A V H X S+ 0 0 0 -4,-2.1 4,-2.2 2,-0.2 -2,-0.2 0.913 113.9 52.2 -67.8 -40.7 20.2 10.3 9.5 22 24 A K H X S+ 0 0 68 -4,-2.5 4,-2.6 1,-0.2 5,-0.3 0.967 108.1 50.7 -58.7 -53.2 20.3 13.8 8.0 23 25 A D H X S+ 0 0 90 -4,-3.3 4,-2.1 1,-0.3 -1,-0.2 0.870 110.4 49.9 -52.4 -41.3 23.8 13.1 6.5 24 26 A K H X S+ 0 0 78 -4,-1.7 4,-1.5 -5,-0.2 -1,-0.3 0.887 110.7 49.6 -65.4 -41.0 22.6 9.9 5.0 25 27 A L H X S+ 0 0 0 -4,-2.2 4,-0.9 -3,-0.2 -2,-0.2 0.885 112.1 47.9 -65.5 -39.6 19.5 11.6 3.5 26 28 A X H < S+ 0 0 64 -4,-2.6 3,-0.2 1,-0.2 -2,-0.2 0.870 107.0 56.8 -69.1 -38.8 21.7 14.4 2.0 27 29 A A H < S+ 0 0 86 -4,-2.1 -1,-0.2 -5,-0.3 -2,-0.2 0.861 116.7 34.7 -62.4 -36.6 24.2 11.9 0.6 28 30 A S H < S+ 0 0 51 -4,-1.5 -1,-0.2 1,-0.2 -2,-0.2 0.538 131.0 31.0 -97.0 -6.9 21.4 10.2 -1.4 29 31 A H >< - 0 0 53 -4,-0.9 3,-1.8 -3,-0.2 -1,-0.2 -0.536 65.5-179.8-149.4 78.4 19.3 13.3 -2.2 30 32 A P T 3 S+ 0 0 111 0, 0.0 -4,-0.1 0, 0.0 -3,-0.1 0.520 78.4 57.7 -60.3 -8.7 21.5 16.4 -2.5 31 33 A G T 3 S+ 0 0 59 2,-0.1 2,-0.3 -5,-0.0 -5,-0.1 0.312 81.0 108.5-106.8 10.8 18.6 18.7 -3.2 32 34 A L < - 0 0 13 -3,-1.8 2,-0.6 -7,-0.2 -29,-0.2 -0.624 61.2-140.1 -89.7 140.9 16.6 18.0 -0.1 33 35 A V E -a 3 0A 66 -31,-2.7 -29,-2.5 -2,-0.3 2,-0.5 -0.910 20.0-161.1 -99.9 123.4 16.2 20.6 2.8 34 36 A V E -a 4 0A 19 -2,-0.6 2,-0.4 -31,-0.2 -29,-0.2 -0.918 6.8-171.4-111.2 126.8 16.4 18.9 6.2 35 37 A E E -a 5 0A 91 -31,-2.5 -29,-3.1 -2,-0.5 2,-0.5 -0.943 15.0-142.0-116.9 135.1 15.0 20.6 9.3 36 38 A L E -a 6 0A 54 -2,-0.4 -29,-0.2 -31,-0.2 -31,-0.1 -0.859 10.2-166.1 -98.5 128.4 15.5 19.3 12.8 37 39 A V E -a 7 0A 36 -31,-3.4 -29,-1.5 -2,-0.5 2,-0.1 -0.886 14.0-154.1-112.8 90.5 12.5 19.8 15.2 38 40 A P E +a 8 0A 70 0, 0.0 -29,-0.2 0, 0.0 -28,-0.1 -0.448 20.1 169.8 -68.5 143.4 13.8 19.1 18.7 39 41 A X - 0 0 26 -31,-2.6 2,-0.2 -2,-0.1 -30,-0.2 0.600 25.3-131.1-111.7-100.4 11.2 18.0 21.2 40 42 A V - 0 0 68 -32,-0.1 2,-0.3 9,-0.1 12,-0.1 -0.570 21.7-142.2 143.3 159.8 11.7 16.6 24.8 41 43 A T > - 0 0 6 -2,-0.2 3,-0.9 1,-0.1 8,-0.2 -0.958 26.5-111.7-146.3 164.4 10.2 13.5 26.2 42 44 A R T 3 S+ 0 0 179 6,-1.9 7,-0.3 -2,-0.3 6,-0.1 0.890 120.2 60.0 -63.6 -32.6 8.6 12.1 29.4 43 45 A G T 3 0 0 49 5,-0.6 -1,-0.3 1,-0.3 6,-0.2 0.767 360.0 360.0 -65.0 -23.6 11.7 9.9 29.6 44 46 A D < 0 0 83 -3,-0.9 -1,-0.3 4,-0.2 -2,-0.2 0.662 360.0 360.0 -70.6 360.0 13.7 13.1 29.7 45 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 46 59 A K 0 0 193 0, 0.0 182,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-160.6 5.7 2.5 28.7 47 60 A G >> + 0 0 16 3,-0.1 4,-1.6 2,-0.0 3,-1.4 0.781 360.0 148.5 81.6 30.3 7.0 4.6 25.8 48 61 A L T 34 S+ 0 0 22 1,-0.3 -6,-1.9 2,-0.2 -5,-0.6 0.855 73.4 48.2 -63.4 -35.2 7.6 7.7 28.0 49 62 A F T 34 S+ 0 0 24 -7,-0.3 -1,-0.3 -8,-0.2 -9,-0.1 0.144 116.1 41.5 -92.5 18.7 10.4 8.7 25.7 50 63 A V T <> S+ 0 0 1 -3,-1.4 4,-1.8 3,-0.0 3,-0.2 0.536 88.1 84.4-136.9 -21.6 8.6 8.3 22.4 51 64 A K H X S+ 0 0 95 -4,-1.6 4,-1.9 1,-0.2 5,-0.1 0.833 88.4 50.0 -60.8 -41.6 5.1 9.7 22.8 52 65 A E H > S+ 0 0 48 -4,-0.3 4,-2.0 1,-0.2 -1,-0.2 0.888 110.1 54.0 -66.7 -34.0 5.6 13.3 22.2 53 66 A L H > S+ 0 0 1 -3,-0.2 4,-1.7 1,-0.2 -2,-0.2 0.898 107.6 48.8 -66.7 -42.1 7.4 12.4 18.9 54 67 A E H X S+ 0 0 4 -4,-1.8 4,-2.4 1,-0.2 -1,-0.2 0.871 109.2 53.4 -65.8 -35.6 4.5 10.3 17.7 55 68 A V H X S+ 0 0 58 -4,-1.9 4,-1.9 2,-0.2 6,-0.2 0.898 105.4 54.5 -63.7 -41.6 2.1 13.3 18.5 56 69 A A H <>S+ 0 0 0 -4,-2.0 5,-3.0 1,-0.2 6,-1.1 0.909 111.1 46.3 -58.7 -40.3 4.4 15.5 16.4 57 70 A L H ><5S+ 0 0 0 -4,-1.7 3,-1.2 3,-0.2 -2,-0.2 0.893 109.7 52.0 -68.7 -43.9 3.9 13.0 13.5 58 71 A L H 3<5S+ 0 0 92 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.798 114.9 41.8 -66.4 -30.0 0.1 12.7 13.9 59 72 A E T 3<5S- 0 0 118 -4,-1.9 -1,-0.3 -5,-0.2 -2,-0.2 0.057 115.7-110.9-106.4 26.1 -0.4 16.4 13.8 60 73 A N T < 5S+ 0 0 89 -3,-1.2 -3,-0.2 2,-0.1 -4,-0.1 0.730 78.6 128.4 54.7 32.4 2.1 17.1 11.0 61 74 A R S > - C 0 188A 26 -2,-0.3 3,-2.5 120,-0.2 4,-0.8 -0.808 44.3-119.6 -88.9 131.7 17.3 3.9 19.0 69 82 A X G >4 S+ 0 0 1 118,-2.9 3,-0.8 -2,-0.5 116,-0.2 0.797 109.8 59.5 -44.7 -38.4 15.6 0.6 18.1 70 83 A K G 34 S+ 0 0 54 114,-0.3 -1,-0.3 117,-0.3 113,-0.1 0.641 104.0 52.0 -70.7 -10.6 15.4 -0.6 21.8 71 84 A D G <4 S+ 0 0 51 -3,-2.5 -1,-0.2 113,-0.1 -2,-0.2 0.617 82.9 105.9 -96.0 -19.0 13.4 2.5 22.7 72 85 A V S << S- 0 0 9 -3,-0.8 -25,-0.0 -4,-0.8 -22,-0.0 -0.480 74.6-122.5 -65.1 124.5 10.7 2.0 20.0 73 86 A P - 0 0 28 0, 0.0 155,-0.1 0, 0.0 -1,-0.1 -0.180 9.6-125.0 -65.2 160.3 7.5 0.7 21.6 74 87 A V S S+ 0 0 34 153,-0.3 2,-0.4 148,-0.1 154,-0.1 0.764 93.2 54.1 -79.4 -23.3 5.9 -2.6 20.4 75 88 A E - 0 0 154 151,-0.1 6,-0.0 6,-0.0 -1,-0.0 -0.886 69.7-159.2-115.0 144.8 2.6 -1.0 19.6 76 89 A F - 0 0 66 -2,-0.4 3,-0.1 4,-0.1 2,-0.1 -0.898 24.1-109.6-124.0 147.9 1.8 1.9 17.3 77 90 A P > - 0 0 34 0, 0.0 3,-2.2 0, 0.0 0, 0.0 -0.440 58.9 -80.7 -68.4 151.6 -1.1 4.4 17.0 78 91 A Q T 3 S+ 0 0 193 1,-0.3 3,-0.1 -2,-0.1 0, 0.0 -0.266 119.5 27.4 -54.7 131.1 -3.1 3.8 13.8 79 92 A G T 3 S+ 0 0 33 1,-0.3 115,-2.3 -3,-0.1 116,-0.5 0.207 106.2 90.5 100.2 -14.5 -1.3 5.4 10.8 80 93 A L E < +D 193 0A 6 -3,-2.2 -1,-0.3 113,-0.3 2,-0.3 -0.784 44.2 142.5-115.0 160.5 2.2 5.2 12.2 81 94 A G E -D 192 0A 7 111,-1.5 111,-2.0 -2,-0.3 2,-0.4 -0.968 51.2 -83.0 178.0 165.4 5.0 2.6 12.1 82 95 A L E +D 191 0A 40 -2,-0.3 109,-0.2 109,-0.2 3,-0.1 -0.703 44.5 162.7 -80.7 127.5 8.6 1.7 11.8 83 96 A V E + 0 0 32 107,-2.8 2,-0.4 -2,-0.4 108,-0.2 0.504 56.3 41.4-127.1 -10.3 9.7 1.8 8.1 84 97 A T E -D 190 0A 3 106,-1.2 106,-2.6 122,-0.1 2,-0.5 -0.992 51.6-170.5-146.5 133.0 13.5 1.9 8.1 85 98 A I E -D 189 0A 18 -2,-0.4 123,-2.6 104,-0.2 127,-0.3 -0.991 22.0-145.9-124.4 117.0 16.2 0.2 10.1 86 99 A C - 0 0 2 102,-2.7 102,-0.2 -2,-0.5 121,-0.1 -0.385 39.4 -63.4 -81.7 164.1 19.7 1.5 9.7 87 100 A E - 0 0 116 119,-0.4 2,-0.2 1,-0.1 -1,-0.2 -0.158 59.1-115.4 -51.2 127.6 22.9 -0.4 9.7 88 101 A R - 0 0 21 99,-0.1 99,-0.2 120,-0.1 2,-0.1 -0.437 25.8-158.5 -72.2 132.8 23.6 -2.0 13.1 89 102 A E - 0 0 62 97,-2.2 70,-0.1 1,-0.2 -1,-0.1 -0.329 56.9 -43.6 -95.1 178.6 26.6 -0.9 15.2 90 103 A D - 0 0 34 1,-0.2 69,-0.6 -2,-0.1 -1,-0.2 -0.273 56.8-161.8 -47.0 119.2 28.3 -3.0 17.9 91 104 A P + 0 0 13 0, 0.0 91,-0.2 0, 0.0 -1,-0.2 0.378 47.0 117.0 -91.0 7.7 25.2 -4.3 19.8 92 105 A R - 0 0 83 89,-0.1 66,-3.0 1,-0.1 67,-0.4 -0.300 64.7-118.3 -82.4 156.1 27.0 -5.3 23.0 93 106 A D E -E 157 0B 0 81,-0.5 81,-2.4 86,-0.4 2,-0.4 -0.538 33.3-139.6 -81.6 157.4 26.8 -4.0 26.6 94 107 A A E -EF 156 173B 0 62,-3.3 62,-1.9 79,-0.2 2,-0.6 -0.940 8.3-135.8-128.9 145.2 29.9 -2.4 28.1 95 108 A F E -EF 155 172B 0 77,-3.1 76,-2.1 -2,-0.4 77,-1.5 -0.884 27.4-173.2 -98.1 120.9 31.6 -2.5 31.4 96 109 A V E +E 154 0B 1 58,-2.5 58,-2.6 -2,-0.6 2,-0.3 -0.984 18.4 141.2-121.0 123.1 32.6 1.0 32.4 97 110 A S E -E 153 0B 6 72,-0.5 56,-0.2 -2,-0.5 55,-0.1 -0.992 41.4-152.9-159.0 153.4 34.7 1.7 35.5 98 111 A N S S+ 0 0 73 54,-0.5 -1,-0.1 -2,-0.3 55,-0.1 0.873 97.9 34.4 -95.8 -41.7 37.5 3.8 36.8 99 112 A N S S+ 0 0 112 53,-0.4 2,-0.4 1,-0.0 54,-0.1 0.647 114.0 50.5 -88.1 -23.5 39.1 1.6 39.4 100 113 A Y - 0 0 65 52,-0.3 -3,-0.1 1,-0.1 3,-0.1 -0.950 56.5-152.6-125.4 148.1 38.6 -2.0 37.9 101 114 A D S S+ 0 0 109 -2,-0.4 2,-0.3 1,-0.1 -6,-0.1 0.656 78.6 6.9 -87.1 -20.1 39.4 -3.6 34.6 102 115 A S S S- 0 0 39 1,-0.1 4,-0.3 -6,-0.0 3,-0.1 -0.955 73.3-103.7-154.3 172.1 36.7 -6.3 34.6 103 116 A L S > S+ 0 0 15 -2,-0.3 3,-1.2 1,-0.2 -1,-0.1 0.817 116.4 61.3 -70.1 -32.6 33.7 -7.6 36.4 104 117 A D T 3 S+ 0 0 141 1,-0.3 -1,-0.2 -3,-0.0 -4,-0.0 0.870 99.6 55.8 -61.6 -39.2 35.7 -10.5 37.9 105 118 A A T 3 S+ 0 0 52 -3,-0.1 -1,-0.3 2,-0.1 -2,-0.2 0.559 80.6 107.2 -71.5 -11.6 37.9 -8.0 39.7 106 119 A L < - 0 0 2 -3,-1.2 3,-0.1 -4,-0.3 2,-0.1 -0.608 68.8-136.9 -73.4 120.1 35.0 -6.4 41.4 107 120 A P > - 0 0 63 0, 0.0 3,-1.7 0, 0.0 -2,-0.1 -0.343 35.9 -77.7 -70.9 160.8 35.1 -7.4 45.1 108 121 A A T 3 S+ 0 0 71 1,-0.2 22,-0.2 22,-0.1 21,-0.0 -0.253 119.2 32.7 -57.7 145.3 32.0 -8.5 47.0 109 122 A G T 3 S+ 0 0 39 20,-2.3 -1,-0.2 1,-0.3 21,-0.1 0.327 81.7 144.9 90.5 -11.4 29.9 -5.5 47.9 110 123 A S < - 0 0 4 -3,-1.7 21,-3.0 1,-0.1 2,-0.5 -0.270 49.1-124.0 -60.0 150.6 30.8 -3.3 44.9 111 124 A I E -g 131 0B 24 19,-0.2 41,-2.3 21,-0.1 42,-1.6 -0.891 25.5-172.6-102.3 123.5 28.0 -1.1 43.6 112 125 A V E -gh 132 153B 0 19,-3.2 21,-2.7 -2,-0.5 2,-0.5 -0.958 15.9-140.9-115.6 132.5 27.2 -1.5 39.9 113 126 A G E +gh 133 154B 0 40,-2.4 42,-1.6 -2,-0.4 2,-0.3 -0.852 41.7 119.3-106.1 131.7 24.7 1.0 38.4 114 127 A T - 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