==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=25-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 24-JUN-97 1AM6 . COMPND 2 MOLECULE: CARBONIC ANHYDRASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR L.R.SCOLNICK,A.M.CLEMENTS,D.W.CHRISTIANSON . 257 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11861.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 162 63.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 56 21.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 22 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 34 13.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 225 0, 0.0 2,-0.2 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-122.4 13.6 -0.7 8.9 2 4 A H - 0 0 117 1,-0.1 0, 0.0 0, 0.0 0, 0.0 -0.566 360.0-101.0 -82.4 144.0 9.9 0.3 8.9 3 5 A W + 0 0 36 -2,-0.2 2,-0.2 1,-0.1 7,-0.2 -0.177 56.8 136.4 -62.1 158.0 7.7 -1.5 11.4 4 6 A G - 0 0 12 5,-2.7 10,-0.1 2,-0.2 -1,-0.1 -0.785 62.9 -83.4-169.1-150.0 5.5 -4.4 10.5 5 7 A Y S S+ 0 0 35 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.165 82.5 111.2-126.4 17.2 4.5 -7.8 11.8 6 8 A G S > S- 0 0 36 1,-0.1 4,-1.5 4,-0.1 3,-0.3 -0.310 84.9 -95.8 -85.8 176.1 7.3 -9.9 10.4 7 9 A K T 4 S+ 0 0 177 1,-0.2 -1,-0.1 2,-0.2 5,-0.0 0.826 123.6 40.1 -60.6 -31.6 10.1 -11.7 12.4 8 10 A H T 4 S+ 0 0 158 1,-0.1 -1,-0.2 5,-0.0 -5,-0.0 0.679 129.4 23.7 -96.5 -14.0 12.5 -8.8 11.8 9 11 A N T 4 S+ 0 0 54 -3,-0.3 -5,-2.7 -6,-0.1 -2,-0.2 0.179 94.9 121.8-135.1 16.6 10.2 -5.7 12.2 10 12 A G S >X S- 0 0 0 -4,-1.5 3,-2.9 -5,-0.2 4,-0.8 -0.003 80.7 -69.5 -75.3-174.7 7.3 -7.1 14.4 11 13 A P T 34 S+ 0 0 23 0, 0.0 3,-0.4 0, 0.0 4,-0.4 0.735 126.8 59.9 -44.9 -38.1 5.8 -6.1 17.8 12 14 A E T 34 S+ 0 0 120 1,-0.2 -5,-0.0 2,-0.1 -2,-0.0 0.582 108.1 45.4 -73.7 -7.2 8.9 -7.3 19.7 13 15 A H T X4 S+ 0 0 55 -3,-2.9 3,-1.7 1,-0.1 4,-0.5 0.590 87.2 90.8-106.9 -16.5 11.1 -4.8 17.9 14 16 A W G >X S+ 0 0 5 -4,-0.8 4,-2.6 -3,-0.4 3,-1.0 0.810 71.8 69.6 -51.6 -37.3 8.8 -1.8 18.1 15 17 A H G 34 S+ 0 0 67 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.783 88.4 66.9 -55.9 -28.2 10.2 -0.4 21.4 16 18 A K G <4 S+ 0 0 133 -3,-1.7 -1,-0.2 1,-0.2 -2,-0.2 0.905 116.6 23.2 -63.0 -41.7 13.5 0.5 19.6 17 19 A D T <4 S+ 0 0 113 -3,-1.0 -2,-0.2 -4,-0.5 -1,-0.2 0.714 135.3 37.7 -94.1 -23.6 11.8 3.2 17.5 18 20 A F >< - 0 0 63 -4,-2.6 3,-2.4 1,-0.1 -1,-0.2 -0.766 64.3-175.7-131.9 85.3 8.8 3.8 19.8 19 21 A P G > S+ 0 0 100 0, 0.0 3,-1.9 0, 0.0 -1,-0.1 0.741 77.9 76.5 -50.9 -28.6 10.0 3.6 23.5 20 22 A I G > + 0 0 54 1,-0.3 3,-2.7 2,-0.2 -5,-0.1 0.669 69.7 89.3 -61.5 -12.8 6.4 4.1 24.6 21 23 A A G < S+ 0 0 6 -3,-2.4 -1,-0.3 1,-0.3 -6,-0.1 0.719 90.4 45.4 -55.2 -26.0 5.9 0.4 23.6 22 24 A K G < S+ 0 0 141 -3,-1.9 -1,-0.3 -7,-0.1 -2,-0.2 0.031 94.6 134.4-105.5 23.6 6.9 -0.5 27.2 23 25 A G < - 0 0 16 -3,-2.7 3,-0.4 1,-0.1 -3,-0.0 0.146 69.3-102.1 -65.5-174.2 4.7 2.2 28.7 24 26 A E S S+ 0 0 123 1,-0.2 226,-0.2 225,-0.1 -1,-0.1 0.615 113.0 34.3 -86.9 -20.3 2.3 2.1 31.6 25 27 A R S S+ 0 0 47 224,-0.1 -1,-0.2 168,-0.1 2,-0.2 -0.380 79.8 156.2-134.4 59.1 -1.0 1.8 29.7 26 28 A Q - 0 0 4 -3,-0.4 220,-0.2 221,-0.3 170,-0.1 -0.539 31.9-102.4 -86.8 149.3 -0.3 -0.2 26.6 27 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.2 78,-0.0 -0.875 77.3 42.5-121.6 159.0 -2.9 -2.2 24.6 28 30 A P + 0 0 0 0, 0.0 218,-3.1 0, 0.0 2,-0.3 0.597 65.4 177.4 -82.0-179.9 -4.1 -4.8 23.9 29 31 A V - 0 0 1 216,-0.3 77,-1.2 -2,-0.2 2,-0.5 -0.893 35.0-101.2-138.2 164.4 -4.6 -6.7 27.2 30 32 A D E -a 106 0A 38 216,-0.4 2,-0.9 -2,-0.3 77,-0.2 -0.778 33.8-136.0 -87.2 134.3 -6.1 -10.0 28.4 31 33 A I E -a 107 0A 0 75,-2.9 77,-2.8 -2,-0.5 2,-1.1 -0.829 12.5-160.0 -95.5 104.9 -9.5 -9.5 29.9 32 34 A D >> - 0 0 65 -2,-0.9 3,-1.4 75,-0.2 4,-0.9 -0.780 3.1-162.6 -84.5 101.6 -9.7 -11.6 33.1 33 35 A T T 34 S+ 0 0 48 -2,-1.1 -1,-0.2 1,-0.3 222,-0.0 0.685 84.1 57.5 -60.5 -19.9 -13.5 -11.9 33.5 34 36 A H T 34 S+ 0 0 158 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.663 112.0 37.2 -88.0 -17.9 -13.2 -12.9 37.1 35 37 A T T <4 S+ 0 0 93 -3,-1.4 2,-0.2 2,-0.1 218,-0.2 0.388 87.2 113.3-111.4 2.2 -11.2 -9.9 38.3 36 38 A A < - 0 0 20 -4,-0.9 2,-0.6 216,-0.1 218,-0.2 -0.554 70.0-123.9 -71.5 135.8 -13.0 -7.3 36.2 37 39 A K E -c 254 0B 126 216,-2.7 218,-2.1 -2,-0.2 2,-0.3 -0.744 10.6-133.6 -92.0 118.7 -14.9 -5.0 38.5 38 40 A Y E -c 255 0B 124 -2,-0.6 218,-0.2 216,-0.2 3,-0.1 -0.520 22.4-164.1 -66.1 122.5 -18.6 -4.6 37.9 39 41 A D > - 0 0 34 216,-2.5 3,-2.0 -2,-0.3 -1,-0.1 -0.864 11.7-171.6-115.0 99.7 -19.2 -0.9 38.0 40 42 A P T 3 S+ 0 0 93 0, 0.0 -1,-0.1 0, 0.0 216,-0.1 0.645 83.3 65.8 -63.6 -15.1 -23.0 -0.1 38.4 41 43 A S T 3 S+ 0 0 81 -3,-0.1 2,-0.3 2,-0.1 215,-0.1 0.570 73.5 110.3 -83.8 -9.5 -22.3 3.6 37.9 42 44 A L < - 0 0 31 -3,-2.0 3,-0.1 213,-0.2 38,-0.0 -0.518 66.1-136.5 -67.7 127.6 -21.2 3.0 34.3 43 45 A K - 0 0 132 37,-0.9 39,-0.1 -2,-0.3 -1,-0.1 -0.383 27.3 -88.1 -81.6 160.8 -23.9 4.5 31.9 44 46 A P - 0 0 109 0, 0.0 36,-2.0 0, 0.0 2,-0.2 -0.329 47.8-102.7 -66.6 154.4 -25.2 2.7 28.8 45 47 A L E -D 79 0B 17 34,-0.3 2,-0.5 141,-0.2 34,-0.2 -0.553 27.7-153.1 -75.9 145.7 -23.3 3.2 25.5 46 48 A S E -D 78 0B 51 32,-2.9 32,-2.0 -2,-0.2 2,-0.6 -0.926 14.2-179.5-125.1 103.7 -24.9 5.6 23.0 47 49 A V E -D 77 0B 33 -2,-0.5 2,-0.7 30,-0.2 30,-0.2 -0.917 3.6-176.8-104.5 113.6 -23.9 4.9 19.4 48 50 A S E +D 76 0B 44 28,-2.9 28,-1.9 -2,-0.6 3,-0.2 -0.802 25.2 142.9-114.6 90.1 -25.4 7.3 16.9 49 51 A Y > + 0 0 3 -2,-0.7 3,-1.8 26,-0.2 130,-0.2 0.302 35.9 105.4-107.7 6.0 -24.4 6.1 13.4 50 52 A D T 3 S+ 0 0 99 1,-0.3 -1,-0.1 -3,-0.1 25,-0.1 0.797 86.8 42.3 -60.6 -26.8 -27.6 6.8 11.5 51 53 A Q T 3 S+ 0 0 126 23,-1.0 -1,-0.3 -3,-0.2 24,-0.2 0.195 84.1 142.6-104.8 18.8 -26.0 9.9 9.7 52 54 A A < - 0 0 24 -3,-1.8 2,-0.5 22,-0.1 18,-0.1 -0.237 35.2-158.5 -60.7 144.4 -22.7 8.2 9.1 53 55 A T - 0 0 48 16,-0.3 16,-2.6 122,-0.1 2,-0.2 -0.895 3.2-161.7-129.6 100.2 -21.0 9.1 5.7 54 56 A S E +E 68 0B 1 -2,-0.5 121,-0.6 122,-0.3 14,-0.3 -0.535 13.6 172.7 -78.4 148.5 -18.4 6.6 4.5 55 57 A L E - 0 0 81 12,-3.0 118,-2.1 1,-0.4 2,-0.3 0.709 51.0 -3.8-124.0 -43.5 -16.0 8.0 1.8 56 58 A R E -EF 67 172B 83 11,-1.0 11,-2.7 116,-0.3 -1,-0.4 -0.949 45.1-138.8-154.4 162.3 -13.2 5.6 1.0 57 59 A I E -EF 66 171B 0 114,-2.2 114,-2.1 -2,-0.3 2,-0.4 -0.986 29.3-173.8-125.8 139.3 -11.5 2.3 1.7 58 60 A L E -EF 65 170B 30 7,-2.2 7,-2.3 -2,-0.4 2,-0.8 -0.995 28.5-141.4-143.1 137.0 -7.7 2.1 1.7 59 61 A N E +E 64 0B 0 110,-2.5 109,-2.9 -2,-0.4 5,-0.2 -0.856 23.5 179.2 -94.3 110.9 -5.0 -0.4 2.0 60 62 A N - 0 0 29 3,-2.1 -1,-0.1 -2,-0.8 4,-0.1 0.291 53.3 -98.4 -97.2 9.0 -2.4 1.3 4.1 61 63 A G S S+ 0 0 14 2,-0.4 3,-0.1 166,-0.2 106,-0.1 0.219 118.0 49.7 96.1 -19.6 0.2 -1.5 4.3 62 64 A H S S- 0 0 51 1,-0.5 2,-0.3 -58,-0.1 166,-0.1 0.531 125.2 -25.2-124.8 -13.6 -0.9 -2.8 7.7 63 65 A A S S- 0 0 2 165,-0.1 -3,-2.1 -5,-0.1 -1,-0.5 -0.914 70.5 -91.9-175.7-177.2 -4.7 -3.2 7.4 64 66 A F E -E 59 0B 0 -2,-0.3 29,-0.5 -5,-0.2 2,-0.4 -0.982 35.6-157.1-118.4 130.9 -7.5 -1.6 5.3 65 67 A N E -E 58 0B 19 -7,-2.3 -7,-2.2 -2,-0.4 2,-0.6 -0.915 10.6-150.3-107.8 139.9 -9.3 1.4 6.7 66 68 A V E -EG 57 91B 0 25,-2.2 25,-1.4 -2,-0.4 2,-0.3 -0.946 27.9-149.2-104.3 117.9 -12.9 2.5 5.8 67 69 A E E -EG 56 90B 49 -11,-2.7 -12,-3.0 -2,-0.6 -11,-1.0 -0.730 10.3-158.7 -95.2 147.6 -12.8 6.3 6.2 68 70 A F E -E 54 0B 9 21,-2.5 2,-0.8 -2,-0.3 -14,-0.2 -0.819 30.0-102.6-121.7 156.4 -15.7 8.5 7.3 69 71 A D + 0 0 38 -16,-2.6 -16,-0.3 -2,-0.3 3,-0.3 -0.705 41.1 173.1 -78.0 111.8 -16.5 12.2 6.9 70 72 A D + 0 0 42 -2,-0.8 -1,-0.1 1,-0.2 17,-0.1 -0.069 44.3 108.6-112.0 32.2 -15.8 13.6 10.4 71 73 A S S S+ 0 0 79 1,-0.1 2,-0.3 56,-0.0 -1,-0.2 0.479 89.2 20.9 -84.4 -1.9 -16.1 17.3 9.7 72 74 A Q S S- 0 0 118 -3,-0.3 2,-2.5 3,-0.1 3,-0.4 -0.976 99.6 -82.5-157.2 161.9 -19.4 17.3 11.6 73 75 A D S S+ 0 0 91 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.385 76.4 127.7 -71.0 73.2 -21.2 15.2 14.3 74 76 A K S S+ 0 0 52 -2,-2.5 -23,-1.0 1,-0.3 2,-0.4 0.778 76.4 21.1 -97.7 -38.2 -22.7 12.6 11.9 75 77 A A S S+ 0 0 6 -3,-0.4 13,-2.6 -24,-0.2 -1,-0.3 -0.924 85.6 163.1-134.5 106.3 -21.5 9.3 13.5 76 78 A V E -DH 48 87B 11 -28,-1.9 -28,-2.9 -2,-0.4 2,-0.4 -0.896 29.6-148.6-130.6 160.6 -20.7 9.7 17.2 77 79 A L E +DH 47 86B 0 9,-2.4 9,-2.0 -2,-0.3 2,-0.3 -0.970 29.8 144.5-126.1 136.5 -20.2 7.7 20.4 78 80 A K E +D 46 0B 61 -32,-2.0 -32,-2.9 -2,-0.4 7,-0.1 -0.911 35.0 54.1-155.0-178.8 -21.0 8.9 23.9 79 81 A G E > S+D 45 0B 22 -2,-0.3 3,-2.1 5,-0.3 -34,-0.3 -0.403 72.1 78.8 80.7-161.2 -22.3 7.6 27.1 80 82 A G T 3 S- 0 0 3 -36,-2.0 -37,-0.9 1,-0.3 -1,-0.1 -0.360 121.8 -24.4 58.8-137.1 -20.6 4.6 28.8 81 83 A P T 3 S+ 0 0 42 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.350 114.6 114.2 -87.4 7.8 -17.4 5.7 30.6 82 84 A L < - 0 0 9 -3,-2.1 2,-0.5 -39,-0.1 -3,-0.2 -0.474 52.2-159.9 -88.0 150.3 -17.1 8.7 28.3 83 85 A D + 0 0 128 -2,-0.2 2,-0.1 53,-0.1 -3,-0.0 -0.999 68.5 2.1-121.4 117.9 -17.3 12.4 29.0 84 86 A G S S- 0 0 43 -2,-0.5 2,-0.4 38,-0.1 -5,-0.3 -0.196 95.3 -55.8 97.4 173.5 -18.1 14.3 25.8 85 87 A T - 0 0 31 -7,-0.1 38,-2.5 -2,-0.1 2,-0.4 -0.765 41.6-162.4 -98.6 135.9 -18.8 13.4 22.2 86 88 A Y E -HI 77 122B 5 -9,-2.0 -9,-2.4 -2,-0.4 2,-0.4 -0.971 11.9-141.1-118.7 130.6 -16.4 11.3 20.1 87 89 A R E -HI 76 121B 46 34,-2.5 34,-1.9 -2,-0.4 2,-0.3 -0.784 17.4-120.3 -93.9 139.6 -16.6 11.3 16.2 88 90 A L E + I 0 120B 2 -13,-2.6 32,-0.3 -2,-0.4 -13,-0.2 -0.535 36.2 166.4 -75.9 128.2 -16.0 8.2 14.1 89 91 A I E - 0 0 39 30,-2.7 -21,-2.5 1,-0.4 2,-0.3 0.709 60.9 -22.0-111.4 -35.3 -13.1 8.7 11.7 90 92 A Q E -GI 67 119B 34 29,-1.1 29,-2.7 -23,-0.2 -1,-0.4 -0.986 47.3-146.2-168.8 160.5 -12.4 5.1 10.6 91 93 A F E +GI 66 118B 0 -25,-1.4 -25,-2.2 -2,-0.3 2,-0.3 -0.961 22.6 164.0-134.1 150.4 -12.8 1.4 11.3 92 94 A H E - 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