==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=15-MAR-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 13-MAR-12 4AMT . COMPND 2 MOLECULE: RENIN; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.ZHOU . 349 4 3 2 1 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16328.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 231 66.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 19 5.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 97 27.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 42 12.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 26 7.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 33 9.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 4 2 3 3 2 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 6 A T 0 0 174 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 173.5 -27.8 21.5 -6.3 2 7 A T - 0 0 138 1,-0.1 2,-0.0 2,-0.0 0, 0.0 -0.569 360.0-139.6 -71.5 127.2 -24.5 21.1 -4.5 3 8 A F - 0 0 72 -2,-0.3 2,-0.5 1,-0.0 -1,-0.1 -0.084 11.3-115.4 -79.9 177.1 -24.8 18.6 -1.6 4 9 A K - 0 0 71 191,-0.3 191,-2.9 2,-0.0 2,-0.3 -0.973 48.6-179.3-118.1 112.9 -23.3 18.6 1.9 5 10 A R E -A 194 0A 91 -2,-0.5 2,-0.5 189,-0.2 189,-0.2 -0.890 34.7-165.8-130.4 141.0 -20.9 15.6 2.1 6 11 A I E -A 193 0A 7 187,-2.8 187,-3.2 -2,-0.3 2,-0.3 -0.981 26.4-146.1-120.2 113.2 -18.6 13.7 4.4 7 12 A F E -A 192 0A 118 -2,-0.5 2,-0.5 185,-0.2 38,-0.4 -0.600 7.7-142.8 -79.9 140.8 -16.4 11.4 2.4 8 13 A L - 0 0 5 183,-2.1 2,-0.3 -2,-0.3 36,-0.2 -0.909 13.6-158.8-106.5 130.0 -15.4 8.1 4.1 9 14 A K E -F 43 0B 63 34,-3.2 34,-1.9 -2,-0.5 2,-0.2 -0.835 21.4-109.5-112.2 145.5 -11.9 6.7 3.5 10 15 A R E +F 42 0B 92 -2,-0.3 32,-0.2 32,-0.2 181,-0.0 -0.491 37.8 175.5 -74.5 137.1 -10.8 3.1 4.0 11 16 A M - 0 0 8 30,-2.1 2,-0.3 -2,-0.2 135,-0.0 -0.973 38.8 -94.9-136.5 152.9 -8.5 2.2 6.9 12 17 A P - 0 0 58 0, 0.0 133,-0.2 0, 0.0 28,-0.1 -0.542 43.2-121.0 -66.8 126.8 -7.1 -1.1 8.1 13 18 A S > - 0 0 2 -2,-0.3 4,-2.9 26,-0.1 5,-0.3 -0.348 20.2-117.7 -59.3 147.3 -9.2 -2.5 10.9 14 19 A I H > S+ 0 0 10 23,-0.4 4,-0.7 24,-0.3 25,-0.2 0.781 121.0 49.7 -63.3 -23.7 -7.3 -3.0 14.2 15 20 A R H > S+ 0 0 25 23,-1.6 4,-1.8 2,-0.2 3,-0.2 0.913 109.7 50.8 -71.8 -46.6 -8.2 -6.7 13.7 16 21 A E H > S+ 0 0 67 22,-0.3 4,-2.5 1,-0.2 3,-0.4 0.937 108.5 50.0 -55.6 -51.5 -6.9 -6.6 10.1 17 22 A S H X S+ 0 0 14 -4,-2.9 4,-1.3 1,-0.3 -1,-0.2 0.784 107.7 55.8 -62.8 -27.5 -3.6 -5.0 11.1 18 23 A L H X>S+ 0 0 38 -4,-0.7 5,-2.6 -5,-0.3 4,-2.2 0.861 107.9 47.7 -68.9 -37.5 -3.2 -7.7 13.8 19 24 A K H <5S+ 0 0 102 -4,-1.8 -2,-0.2 -3,-0.4 -1,-0.2 0.903 108.4 53.9 -68.5 -41.9 -3.5 -10.4 11.1 20 25 A E H <5S+ 0 0 154 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.856 111.7 46.8 -56.0 -37.1 -1.0 -8.6 8.9 21 26 A R H <5S- 0 0 164 -4,-1.3 -2,-0.2 -5,-0.2 -1,-0.2 0.889 119.1-117.3 -70.4 -42.6 1.3 -8.7 11.9 22 27 A G T <5 + 0 0 62 -4,-2.2 -3,-0.2 1,-0.2 2,-0.1 0.690 48.6 171.3 109.0 33.0 0.4 -12.4 12.4 23 28 A V < - 0 0 51 -5,-2.6 2,-0.7 1,-0.1 -1,-0.2 -0.442 38.4-120.3 -76.8 142.1 -1.2 -12.4 15.8 24 29 A D - 0 0 87 1,-0.2 3,-0.5 -2,-0.1 4,-0.2 -0.753 23.0-160.2 -76.6 116.4 -3.0 -15.4 17.3 25 30 A M S > S+ 0 0 27 -2,-0.7 3,-1.2 1,-0.2 -1,-0.2 0.836 85.3 58.8 -71.6 -33.7 -6.6 -14.1 17.8 26 31 A A T 3 S+ 0 0 91 1,-0.2 -1,-0.2 -3,-0.1 -2,-0.0 0.750 96.7 62.5 -67.1 -25.5 -7.5 -16.8 20.3 27 32 A R T 3 S+ 0 0 212 -3,-0.5 -1,-0.2 2,-0.0 -2,-0.2 0.441 87.1 91.8 -85.0 -1.3 -4.7 -15.8 22.7 28 33 A L S < S- 0 0 67 -3,-1.2 -3,-0.0 1,-0.2 0, 0.0 -0.258 90.3 -85.6 -74.9 175.4 -6.3 -12.3 23.2 29 34 A G - 0 0 42 1,-0.1 -1,-0.2 -2,-0.1 78,-0.0 -0.210 49.5 -89.4 -73.2 172.5 -8.7 -11.5 26.0 30 35 A P 0 0 140 0, 0.0 -1,-0.1 0, 0.0 77,-0.0 0.419 360.0 360.0 -63.8 6.1 -12.5 -12.2 25.7 31 36 A E 0 0 83 76,-0.1 76,-0.2 75,-0.0 75,-0.2 0.864 360.0 360.0 69.2 360.0 -12.6 -8.6 24.3 32 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 33 54 A I 0 0 159 0, 0.0 2,-0.3 0, 0.0 73,-0.1 0.000 360.0 360.0 360.0 37.5 -21.8 0.8 27.0 34 55 A L + 0 0 87 71,-0.1 2,-0.1 72,-0.1 71,-0.1 -0.899 360.0 126.8-163.1 129.8 -20.2 -1.2 24.1 35 56 A T - 0 0 23 -2,-0.3 211,-0.0 210,-0.0 -1,-0.0 -0.444 27.4-166.0-168.4 109.6 -19.0 -0.9 20.5 36 57 A N - 0 0 30 -2,-0.1 210,-0.1 1,-0.1 69,-0.0 0.788 14.9-151.0 -67.8 -29.1 -15.4 -2.1 20.0 37 58 A Y > + 0 0 3 208,-0.1 3,-0.7 1,-0.1 -23,-0.4 0.779 51.4 140.1 55.5 28.6 -14.9 -0.7 16.5 38 59 A M T 3 S+ 0 0 15 1,-0.3 -23,-1.6 -25,-0.1 -22,-0.3 0.857 74.6 29.7 -72.9 -35.0 -12.6 -3.6 16.3 39 60 A D T 3 S+ 0 0 10 -25,-0.2 2,-0.3 -26,-0.1 -1,-0.3 0.100 88.4 131.7-110.3 19.8 -13.6 -4.4 12.7 40 61 A T < + 0 0 11 -3,-0.7 -26,-0.3 1,-0.1 -25,-0.1 -0.606 26.3 174.2 -76.2 131.9 -14.4 -0.8 11.7 41 62 A Q + 0 0 25 -2,-0.3 -30,-2.1 -28,-0.1 2,-0.3 0.181 49.1 68.7-128.3 13.5 -12.8 0.0 8.4 42 63 A Y E +F 10 0B 18 -32,-0.2 2,-0.3 203,-0.1 -32,-0.2 -0.997 48.2 169.0-141.0 142.7 -14.0 3.5 7.4 43 64 A Y E -F 9 0B 36 -34,-1.9 -34,-3.2 -2,-0.3 2,-0.3 -0.978 15.4-155.7-145.0 157.0 -13.5 7.0 8.7 44 65 A G E -G 57 0C 0 13,-3.0 13,-3.5 -2,-0.3 2,-0.3 -0.768 25.3-114.3-119.1 173.7 -14.2 10.7 7.8 45 66 A E E -G 56 0C 82 -38,-0.4 77,-0.5 -2,-0.3 2,-0.3 -0.816 27.2-177.3-109.0 151.0 -12.4 13.9 9.0 46 67 A I E -G 55 0C 6 9,-1.8 9,-2.3 -2,-0.3 2,-0.3 -0.917 20.4-129.8-133.8 162.5 -13.8 16.7 11.0 47 68 A G E -GH 54 120C 4 73,-3.2 73,-0.7 -2,-0.3 2,-0.4 -0.844 15.8-162.6-103.8 152.0 -12.4 20.0 12.2 48 69 A I E > -GH 53 119C 0 5,-0.8 5,-1.2 -2,-0.3 71,-0.2 -0.908 52.3 -11.5-137.3 113.8 -12.6 21.2 15.9 49 70 A G T 5S- 0 0 3 69,-3.4 71,-0.1 -2,-0.4 42,-0.1 -0.320 96.3 -36.7 99.4 178.6 -12.1 24.8 16.8 50 71 A T T 5S+ 0 0 48 2,-0.1 42,-0.3 -2,-0.1 44,-0.1 -0.823 133.7 28.8 -99.9 146.9 -10.9 28.0 15.1 51 72 A P T 5S- 0 0 91 0, 0.0 2,-0.4 0, 0.0 -3,-0.1 0.875 117.5-108.9 17.0 127.5 -8.3 27.3 13.0 52 73 A P T 5 - 0 0 77 0, 0.0 2,-0.8 0, 0.0 -3,-0.2 -0.549 25.9-152.4 -68.6 120.2 -9.8 23.8 12.5 53 74 A Q E < -G 48 0C 35 -5,-1.2 -5,-0.8 -2,-0.4 2,-0.2 -0.879 26.2-138.5 -86.8 110.7 -7.7 21.1 14.1 54 75 A T E -G 47 0C 59 -2,-0.8 2,-0.3 -7,-0.2 -7,-0.2 -0.497 23.6-175.4 -84.5 144.0 -8.5 18.1 11.9 55 76 A F E -G 46 0C 2 -9,-2.3 -9,-1.8 -2,-0.2 2,-0.5 -0.992 28.1-124.6-137.4 142.5 -9.2 14.6 13.2 56 77 A K E +G 45 0C 50 -2,-0.3 91,-3.4 -11,-0.2 92,-2.1 -0.760 45.0 170.1 -83.0 122.7 -9.9 11.2 11.6 57 78 A V E -Gi 44 148C 0 -13,-3.5 -13,-3.0 -2,-0.5 2,-0.4 -0.974 34.2-129.0-137.4 149.1 -13.1 9.9 13.1 58 79 A V E - i 0 149C 2 90,-1.8 92,-2.4 -2,-0.3 2,-0.7 -0.813 24.0-134.2 -94.0 141.5 -15.7 7.1 12.7 59 80 A F E - i 0 150C 10 -2,-0.4 2,-0.6 90,-0.2 92,-0.2 -0.871 26.7-171.5-100.4 111.8 -19.3 8.1 12.4 60 81 A D E > - i 0 151C 0 90,-2.0 92,-2.1 -2,-0.7 3,-1.8 -0.880 24.2-172.5-120.2 102.9 -21.3 5.8 14.6 61 82 A T T 3 S+ 0 0 3 -2,-0.6 157,-0.4 1,-0.3 93,-0.2 0.548 86.6 69.6 -66.9 -8.5 -25.1 5.8 14.6 62 83 A G T 3 S+ 0 0 30 91,-0.1 2,-0.3 155,-0.1 -1,-0.3 0.454 101.0 45.2 -88.6 -4.0 -24.9 3.4 17.6 63 84 A S < - 0 0 23 -3,-1.8 90,-2.2 87,-0.1 89,-1.2 -0.958 61.3-150.8-140.6 162.8 -23.6 6.1 20.0 64 85 A S + 0 0 0 93,-1.1 2,-0.3 -2,-0.3 94,-0.1 0.048 62.9 90.8-125.5 22.6 -24.4 9.8 20.9 65 86 A N - 0 0 13 92,-0.1 86,-1.5 99,-0.1 2,-0.5 -0.862 56.6-146.3-118.9 154.6 -21.1 11.3 22.0 66 87 A V E +J 150 0C 3 -2,-0.3 65,-2.7 63,-0.3 2,-0.3 -0.989 30.3 164.4-115.1 122.0 -18.4 13.2 20.2 67 88 A W E +Jk 149 131C 3 82,-2.0 82,-2.2 -2,-0.5 65,-0.2 -0.997 14.0 172.7-145.4 144.1 -14.9 12.7 21.5 68 89 A V E - k 0 132C 0 63,-2.1 65,-2.4 -2,-0.3 2,-0.2 -0.834 44.7 -80.9-132.7 167.6 -11.3 13.2 20.5 69 90 A P E - k 0 133C 0 0, 0.0 17,-2.5 0, 0.0 2,-0.3 -0.497 46.6-128.2 -74.6 148.7 -7.9 12.9 22.2 70 91 A S B > -n 86 0D 0 63,-2.1 3,-1.3 15,-0.3 17,-0.2 -0.647 11.3-132.6 -96.3 148.7 -6.8 15.8 24.4 71 92 A S T 3 S+ 0 0 45 15,-2.0 16,-0.1 -2,-0.3 -1,-0.1 0.689 106.9 70.2 -63.9 -18.4 -3.5 17.7 24.4 72 93 A K T 3 + 0 0 145 14,-0.3 -1,-0.2 2,-0.1 2,-0.2 0.175 64.2 135.1 -91.2 16.3 -3.7 17.1 28.1 73 94 A a S < S- 0 0 10 -3,-1.3 2,-2.8 1,-0.1 62,-0.1 -0.492 71.7-109.3 -58.4 132.6 -3.0 13.3 27.8 74 95 A S > - 0 0 78 60,-0.7 3,-1.3 -2,-0.2 4,-0.2 -0.328 51.0-101.7 -73.7 66.2 -0.4 12.6 30.6 75 96 A R G > S- 0 0 206 -2,-2.8 3,-0.8 1,-0.2 4,-0.4 -0.187 88.6 -12.4 52.9-137.9 2.5 12.0 28.2 76 97 A L G 3 S+ 0 0 133 1,-0.2 3,-0.5 2,-0.1 -1,-0.2 0.713 122.5 77.7 -67.2 -22.2 3.5 8.3 27.6 77 98 A Y G < S+ 0 0 208 -3,-1.3 -1,-0.2 1,-0.2 -2,-0.2 0.803 94.1 43.4 -59.5 -36.5 1.3 7.0 30.5 78 99 A T S < S- 0 0 13 -3,-0.8 58,-1.1 -4,-0.2 -1,-0.2 0.652 87.0-139.9 -94.7 -21.3 -2.1 7.2 28.8 79 100 A A S S+ 0 0 12 -3,-0.5 3,-0.3 -4,-0.4 -3,-0.1 0.527 81.6 97.5 68.1 7.2 -1.5 5.8 25.3 80 101 A a > + 0 0 0 -5,-0.3 3,-0.9 54,-0.2 -1,-0.1 0.657 62.1 80.9 -87.9 -20.5 -3.8 8.4 23.7 81 102 A V T 3 S+ 0 0 51 -6,-0.4 -1,-0.1 1,-0.3 4,-0.1 0.546 73.6 78.4 -65.3 -3.8 -0.7 10.6 22.9 82 103 A Y T 3 S+ 0 0 110 -3,-0.3 -1,-0.3 2,-0.1 2,-0.2 -0.003 94.0 53.2 -94.3 28.6 -0.2 8.3 19.8 83 104 A H S < S- 0 0 29 -3,-0.9 2,-0.2 64,-0.0 64,-0.1 -0.830 106.6 -64.8-141.8 178.9 -3.0 10.1 17.9 84 105 A K - 0 0 97 -2,-0.2 2,-0.4 -28,-0.1 -2,-0.1 -0.529 53.6-146.9 -69.0 140.5 -3.8 13.8 17.0 85 106 A L - 0 0 50 -2,-0.2 2,-0.8 -4,-0.1 -15,-0.3 -0.893 11.0-124.3-115.9 140.8 -4.5 15.8 20.1 86 107 A F B -n 70 0D 0 -17,-2.5 -15,-2.0 -2,-0.4 2,-0.7 -0.752 23.4-160.9 -85.0 111.5 -7.0 18.8 20.5 87 108 A D > - 0 0 53 -2,-0.8 3,-1.0 -17,-0.2 4,-0.1 -0.872 7.1-166.5 -94.0 116.4 -5.0 21.7 21.8 88 109 A A G > S+ 0 0 17 -2,-0.7 3,-1.3 1,-0.2 6,-0.2 0.723 83.2 69.9 -73.0 -23.1 -7.5 24.2 23.3 89 110 A S G 3 S+ 0 0 107 1,-0.3 -1,-0.2 -3,-0.1 -2,-0.0 0.477 95.4 54.2 -75.6 -3.1 -4.8 26.9 23.3 90 111 A D G < S+ 0 0 95 -3,-1.0 2,-0.5 -39,-0.1 -1,-0.3 0.377 95.4 81.8-106.4 -0.4 -4.9 27.1 19.5 91 112 A S < - 0 0 14 -3,-1.3 3,-0.2 1,-0.1 -42,-0.1 -0.929 50.9-172.3-112.4 126.5 -8.7 27.7 19.3 92 113 A S S S+ 0 0 101 -2,-0.5 -1,-0.1 -42,-0.3 -4,-0.0 0.821 91.6 54.8 -79.4 -34.8 -10.2 31.2 19.8 93 114 A S S S+ 0 0 25 25,-0.1 -1,-0.2 2,-0.0 -44,-0.1 0.532 81.5 122.4 -73.5 -9.4 -13.7 29.6 19.8 94 115 A Y - 0 0 61 -6,-0.2 2,-0.4 -3,-0.2 23,-0.2 -0.275 42.7-166.0 -58.9 137.8 -12.9 27.2 22.6 95 116 A K E -L 116 0C 133 21,-2.5 21,-2.0 0, 0.0 -2,-0.0 -0.979 18.1-122.4-131.4 124.8 -15.1 27.4 25.7 96 117 A H E +L 115 0C 144 -2,-0.4 19,-0.1 19,-0.2 0, 0.0 -0.129 44.0 144.5 -60.0 148.9 -14.3 25.7 29.0 97 118 A N E - 0 0 58 17,-0.6 18,-0.2 19,-0.0 -1,-0.1 0.203 19.3-176.5-144.1 -67.6 -16.5 23.2 30.8 98 119 A G E + 0 0 34 16,-2.2 2,-0.4 1,-0.3 17,-0.1 0.559 21.9 152.0 81.7 10.5 -14.4 20.5 32.5 99 120 A T E - 0 0 69 1,-0.1 15,-1.3 15,-0.0 -1,-0.3 -0.629 53.1-110.4 -74.1 125.6 -17.2 18.3 33.8 100 121 A E E -L 113 0C 178 -2,-0.4 2,-0.4 13,-0.2 13,-0.2 -0.275 33.2-160.1 -60.9 143.8 -15.6 14.8 34.0 101 122 A L E -L 112 0C 14 11,-3.1 11,-1.5 31,-0.1 2,-0.3 -0.970 7.2-166.2-127.3 142.2 -16.9 12.2 31.5 102 123 A T E -L 111 0C 60 -2,-0.4 2,-0.5 9,-0.2 9,-0.2 -0.760 4.4-176.9-137.6 89.9 -16.6 8.4 31.8 103 124 A L E -L 110 0C 13 7,-1.6 7,-2.3 -2,-0.3 2,-0.5 -0.763 17.2-152.4 -84.1 121.9 -17.3 6.2 28.7 104 125 A R E -L 109 0C 174 -2,-0.5 2,-0.3 5,-0.2 5,-0.2 -0.842 15.3-179.3-102.0 128.9 -17.0 2.5 29.7 105 126 A Y - 0 0 30 3,-2.4 3,-0.2 -2,-0.5 -71,-0.1 -0.851 40.0-113.1-120.8 161.9 -16.0 -0.1 27.1 106 127 A S S S+ 0 0 57 -2,-0.3 3,-0.1 1,-0.2 -72,-0.1 0.764 119.5 43.9 -64.3 -28.0 -15.7 -3.9 27.4 107 128 A T S S- 0 0 37 1,-0.3 2,-0.3 -76,-0.2 -1,-0.2 0.692 130.9 -39.0 -89.2 -23.1 -11.9 -3.7 26.8 108 129 A G - 0 0 20 -3,-0.2 -3,-2.4 29,-0.1 2,-0.6 -0.978 62.1 -80.4 175.5 178.1 -11.4 -0.6 29.2 109 130 A T E -L 104 0C 79 -2,-0.3 2,-0.5 -5,-0.2 -5,-0.2 -0.894 31.8-151.1-109.0 114.9 -12.6 2.7 30.6 110 131 A V E -L 103 0C 0 -7,-2.3 -7,-1.6 -2,-0.6 2,-0.3 -0.726 19.2-169.6 -83.7 123.9 -12.1 5.9 28.6 111 132 A S E +LM 102 135C 28 24,-1.5 23,-2.4 -2,-0.5 24,-2.2 -0.857 22.3 114.8-117.7 153.0 -11.8 9.0 30.8 112 133 A G E -LM 101 133C 8 -11,-1.5 -11,-3.1 -2,-0.3 2,-0.3 -0.967 47.9 -92.1 174.9-172.8 -11.7 12.7 30.0 113 134 A F E -LM 100 132C 39 19,-2.3 19,-4.0 -2,-0.3 -13,-0.2 -0.808 36.2 -97.3-127.6 167.7 -13.5 16.1 30.3 114 135 A L E + M 0 131C 15 -15,-1.3 -16,-2.2 -2,-0.3 -17,-0.6 -0.512 37.0 174.2 -89.9 152.0 -16.0 18.2 28.4 115 136 A S E -LM 96 130C 0 15,-2.2 15,-2.7 -18,-0.2 2,-0.4 -0.987 20.8-137.4-153.5 150.1 -15.3 21.0 26.1 116 137 A Q E +LM 95 129C 60 -21,-2.0 -21,-2.5 -2,-0.3 2,-0.3 -0.946 35.5 136.6-116.5 139.1 -17.2 23.3 23.8 117 138 A D E - M 0 128C 0 11,-2.6 11,-2.6 -2,-0.4 2,-0.2 -0.944 55.3 -84.1-170.1 154.7 -16.2 24.4 20.3 118 139 A I E - M 0 127C 49 -2,-0.3 -69,-3.4 9,-0.3 2,-0.5 -0.445 41.9-155.0 -54.5 122.8 -17.1 24.9 16.7 119 140 A I E -HM 48 126C 0 7,-4.1 7,-2.9 -71,-0.2 2,-0.6 -0.968 3.7-150.7-103.3 121.3 -16.9 21.7 14.8 120 141 A T E +HM 47 125C 52 -73,-0.7 -73,-3.2 -2,-0.5 2,-0.3 -0.820 30.8 162.3 -80.8 120.4 -16.4 21.9 11.0 121 142 A V - 0 0 4 3,-2.9 3,-0.3 -2,-0.6 -75,-0.1 -0.984 57.8 -13.8-143.1 138.2 -18.0 18.8 9.4 122 143 A G S S- 0 0 11 -77,-0.5 73,-0.1 -2,-0.3 -116,-0.1 0.876 131.6 -44.0 43.1 49.5 -19.2 18.0 5.9 123 144 A G S S+ 0 0 67 1,-0.1 -1,-0.2 -119,-0.1 2,-0.2 0.901 122.7 85.4 62.6 44.1 -18.8 21.6 4.8 124 145 A I - 0 0 43 -3,-0.3 -3,-2.9 2,-0.0 2,-0.7 -0.928 69.0-117.3-168.5 157.1 -20.5 23.2 7.8 125 146 A T E + M 0 120C 93 -2,-0.2 2,-0.5 -5,-0.2 -5,-0.2 -0.787 24.9 176.7-102.1 109.9 -20.0 24.6 11.4 126 147 A V E - M 0 119C 4 -7,-2.9 -7,-4.1 -2,-0.7 2,-0.8 -0.957 28.7-135.7-101.9 126.8 -21.8 23.1 14.4 127 148 A T E + M 0 118C 49 -2,-0.5 2,-0.3 -9,-0.3 -9,-0.3 -0.736 41.9 179.0 -69.8 108.2 -21.0 24.5 17.8 128 149 A Q E - M 0 117C 0 -11,-2.6 -11,-2.6 -2,-0.8 2,-0.5 -0.810 34.3-136.9-111.9 156.8 -20.7 21.2 19.7 129 150 A M E + M 0 116C 38 34,-0.4 -63,-0.3 -2,-0.3 -13,-0.2 -0.979 41.7 164.7-106.3 125.0 -19.9 20.1 23.3 130 151 A F E - M 0 115C 2 -15,-2.7 -15,-2.2 -2,-0.5 2,-0.4 -0.698 36.7 -91.2-130.4 176.2 -17.5 17.1 23.2 131 152 A G E -kM 67 114C 2 -65,-2.7 -63,-2.1 -17,-0.2 2,-0.7 -0.820 19.3-155.5 -97.5 132.5 -15.2 14.9 25.3 132 153 A E E -kM 68 113C 2 -19,-4.0 -19,-2.3 -2,-0.4 2,-0.4 -0.944 25.4-142.8-100.5 111.3 -11.4 15.6 25.6 133 154 A V E +kM 69 112C 2 -65,-2.4 -63,-2.1 -2,-0.7 -21,-0.3 -0.629 31.3 168.5 -87.3 129.0 -10.0 12.2 26.5 134 155 A T E S+ 0 0 32 -23,-2.4 -60,-0.7 -2,-0.4 2,-0.3 0.485 70.7 42.1-113.4 -10.1 -7.1 12.0 29.0 135 156 A E E + M 0 111C 109 -24,-2.2 -24,-1.5 -62,-0.1 -1,-0.2 -0.993 67.0 178.7-139.8 134.5 -7.1 8.2 29.5 136 157 A M - 0 0 20 -58,-1.1 2,-0.4 -2,-0.3 -26,-0.1 -0.963 34.8-106.0-136.3 145.1 -7.4 5.5 26.9 137 158 A P > - 0 0 14 0, 0.0 4,-1.0 0, 0.0 5,-0.4 -0.625 24.8-149.2 -68.5 123.1 -7.4 1.7 26.7 138 159 A A H > S+ 0 0 61 -2,-0.4 4,-1.3 3,-0.2 5,-0.3 0.844 82.5 71.2 -60.6 -35.7 -4.1 0.5 25.2 139 160 A L H 4 S+ 0 0 89 -32,-0.2 4,-0.4 1,-0.2 -1,-0.1 0.946 114.5 8.9 -56.4 -72.1 -5.7 -2.6 23.6 140 161 A P H >> S+ 0 0 4 0, 0.0 3,-1.0 0, 0.0 4,-0.9 0.950 126.7 54.4 -75.8 -42.6 -7.8 -1.4 20.7 141 162 A F H 3< S+ 0 0 4 -4,-1.0 3,-0.2 1,-0.3 -3,-0.2 0.760 96.5 59.6 -73.8 -31.0 -7.0 2.3 20.5 142 163 A M T 3< S+ 0 0 84 -4,-1.3 -1,-0.3 -5,-0.4 -3,-0.1 0.777 111.5 44.6 -68.0 -23.3 -3.2 2.3 20.1 143 164 A L T <4 S+ 0 0 48 -3,-1.0 -1,-0.2 -4,-0.4 -2,-0.2 0.668 91.8 115.6 -87.0 -21.6 -3.6 0.2 16.9 144 165 A A < - 0 0 9 -4,-0.9 -131,-0.1 -3,-0.2 -106,-0.0 -0.068 52.4-160.7 -48.2 142.7 -6.5 2.5 15.7 145 166 A E S S+ 0 0 100 -133,-0.2 2,-0.2 -62,-0.0 -1,-0.1 0.549 75.6 79.0 -96.1 -15.8 -6.0 4.5 12.5 146 167 A F - 0 0 4 1,-0.1 -89,-0.2 -91,-0.1 3,-0.1 -0.612 67.7-153.3 -89.5 153.6 -8.9 6.8 13.6 147 168 A D - 0 0 6 -91,-3.4 2,-0.2 -2,-0.2 -90,-0.2 0.797 66.3 -16.4 -93.1 -37.3 -8.4 9.5 16.2 148 169 A G E -i 57 0C 0 -92,-2.1 -90,-1.8 -80,-0.1 2,-0.4 -0.826 61.4 -94.2-155.7-168.8 -12.0 9.8 17.6 149 170 A V E -iJ 58 67C 1 -82,-2.2 -82,-2.0 -92,-0.2 2,-0.5 -0.932 14.3-162.2-126.1 141.3 -15.7 9.1 17.4 150 171 A V E -iJ 59 66C 0 -92,-2.4 -90,-2.0 -2,-0.4 -84,-0.2 -0.956 21.4-140.5-123.9 110.5 -18.7 11.2 16.2 151 172 A G E -i 60 0C 0 -86,-1.5 15,-0.3 -2,-0.5 -87,-0.2 -0.410 21.5-179.4 -66.0 138.5 -22.0 10.0 17.5 152 173 A M + 0 0 8 -92,-2.1 -91,-0.2 -89,-1.2 -88,-0.2 0.149 56.3 100.8-118.0 16.5 -25.0 10.0 15.2 153 174 A G S S- 0 0 8 -90,-2.2 13,-0.2 -93,-0.5 2,-0.2 -0.107 75.3 -79.1 -90.4-169.6 -27.3 8.8 17.9 154 175 A F > - 0 0 4 62,-0.4 3,-1.3 -93,-0.2 -1,-0.1 -0.503 34.1-109.2 -99.0 159.5 -29.9 10.4 20.2 155 176 A I G > S+ 0 0 36 1,-0.3 3,-1.7 2,-0.2 6,-0.2 0.781 114.1 66.6 -55.2 -31.3 -29.6 12.3 23.4 156 177 A E G 3 S+ 0 0 86 1,-0.3 -1,-0.3 5,-0.1 5,-0.1 0.875 105.1 42.5 -60.5 -38.6 -31.0 9.4 25.4 157 178 A Q G < S+ 0 0 96 -3,-1.3 -93,-1.1 59,-0.3 2,-0.5 -0.079 92.7 110.0 -99.3 31.9 -27.9 7.3 24.6 158 179 A A S X S- 0 0 7 -3,-1.7 3,-1.9 -95,-0.1 2,-0.3 -0.945 71.5-127.5-107.5 121.6 -25.5 10.3 25.2 159 180 A I T 3 S+ 0 0 75 -2,-0.5 3,-0.5 1,-0.3 -2,-0.1 -0.538 101.1 19.0 -64.6 125.3 -23.3 10.1 28.4 160 181 A G T 3 S- 0 0 63 -2,-0.3 -1,-0.3 1,-0.2 3,-0.1 0.538 119.6 -91.1 88.9 11.3 -24.0 13.3 30.2 161 182 A R S < S+ 0 0 174 -3,-1.9 2,-0.3 1,-0.2 -1,-0.2 0.793 73.4 172.8 51.0 31.5 -27.2 14.0 28.4 162 183 A V - 0 0 16 -3,-0.5 -1,-0.2 1,-0.1 -3,-0.0 -0.509 38.5-107.9 -78.5 131.5 -25.0 15.9 25.9 163 184 A T - 0 0 52 -2,-0.3 -34,-0.4 -3,-0.1 -1,-0.1 -0.341 37.5-120.4 -61.8 122.1 -26.7 17.1 22.7 164 185 A P >> - 0 0 1 0, 0.0 4,-1.9 0, 0.0 3,-1.2 -0.374 21.2-111.0 -68.4 140.4 -25.6 15.1 19.7 165 186 A I H 3> S+ 0 0 3 1,-0.3 4,-2.2 2,-0.2 -13,-0.1 0.764 119.3 51.9 -36.2 -36.4 -23.9 16.8 16.8 166 187 A F H 3> S+ 0 0 6 -15,-0.3 4,-2.9 -13,-0.2 -1,-0.3 0.901 105.7 51.0 -75.6 -40.3 -26.9 16.1 14.6 167 188 A D H <> S+ 0 0 31 -3,-1.2 4,-2.8 2,-0.2 5,-0.3 0.984 114.0 47.0 -52.8 -56.0 -29.5 17.5 17.1 168 189 A N H X S+ 0 0 25 -4,-1.9 4,-2.4 1,-0.2 -2,-0.2 0.878 108.1 55.6 -54.4 -41.7 -27.3 20.6 17.1 169 190 A I H < S+ 0 0 6 -4,-2.2 -1,-0.2 -5,-0.3 -2,-0.2 0.960 112.9 42.6 -56.3 -48.0 -27.1 20.5 13.4 170 191 A I H < S+ 0 0 48 -4,-2.9 -2,-0.2 1,-0.2 5,-0.2 0.985 117.9 42.0 -60.4 -60.8 -30.9 20.6 13.2 171 192 A S H < S+ 0 0 97 -4,-2.8 2,-0.6 -5,-0.1 -1,-0.2 0.869 115.3 50.8 -61.4 -44.6 -31.7 23.2 15.9 172 193 A Q S < S- 0 0 73 -4,-2.4 -1,-0.1 -5,-0.3 -45,-0.0 -0.857 112.2 -17.3 -99.6 125.5 -28.9 25.6 14.9 173 194 A G S S- 0 0 67 -2,-0.6 2,-0.5 1,-0.0 -47,-0.0 -0.099 89.1 -48.1 80.9-175.5 -28.6 26.7 11.3 174 195 A V + 0 0 116 3,-0.0 2,-0.3 0, 0.0 3,-0.1 -0.849 41.7 159.9-115.4 118.2 -29.9 25.3 8.1 175 196 A L - 0 0 13 -2,-0.5 3,-0.1 1,-0.2 21,-0.1 -0.896 43.2-126.6-110.8 155.2 -30.0 21.9 6.6 176 197 A K S S+ 0 0 167 -2,-0.3 2,-0.3 1,-0.3 -1,-0.2 0.999 92.9 6.7 -60.4 -66.9 -32.6 21.4 3.8 177 198 A E S S- 0 0 105 19,-0.7 2,-2.0 2,-0.1 -1,-0.3 -0.918 80.2-115.6-119.4 146.9 -34.1 18.3 5.5 178 199 A D S S+ 0 0 41 -2,-0.3 164,-1.9 -3,-0.1 163,-0.7 -0.520 81.1 91.7 -82.2 74.7 -33.3 16.9 9.0 179 200 A V E -B 340 0A 8 -2,-2.0 17,-1.7 161,-0.2 2,-0.3 -0.885 52.4-157.7-147.2 175.4 -31.9 13.6 7.8 180 201 A F E -BC 339 195A 0 159,-1.4 159,-3.8 -2,-0.3 2,-0.3 -0.938 8.2-152.3-159.1 152.6 -28.7 12.0 6.8 181 202 A S E -BC 338 194A 0 13,-2.0 13,-1.6 16,-0.4 2,-0.3 -0.873 3.8-146.3-126.8 157.4 -27.7 9.0 4.7 182 203 A F E +BC 337 193A 1 155,-2.0 155,-1.4 -2,-0.3 2,-0.3 -0.939 16.0 178.1-120.4 146.4 -24.8 6.5 4.5 183 204 A Y E - C 0 192A 9 9,-1.1 9,-2.7 -2,-0.3 2,-0.4 -0.959 7.8-167.9-150.3 130.6 -23.3 4.8 1.4 184 205 A Y - 0 0 8 148,-0.5 7,-0.2 -2,-0.3 2,-0.1 -0.943 20.0-129.5-117.5 137.9 -20.4 2.4 0.9 185 206 A N - 0 0 51 -2,-0.4 2,-1.7 5,-0.2 5,-0.1 -0.466 33.4-104.1 -73.5 155.4 -18.8 1.4 -2.4 186 207 A R 0 0 151 -2,-0.1 -1,-0.1 147,-0.1 148,-0.0 -0.640 360.0 360.0 -77.7 83.3 -18.3 -2.3 -3.2 187 208 A D 0 0 127 -2,-1.7 -3,-0.0 3,-0.1 0, 0.0 -0.679 360.0 360.0-170.9 360.0 -14.5 -2.2 -2.4 188 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 189 215 A L 0 0 155 0, 0.0 2,-0.6 0, 0.0 -181,-0.1 0.000 360.0 360.0 360.0 4.5 -11.3 5.6 -0.3 190 216 A G + 0 0 0 -5,-0.1 2,-0.2 -183,-0.1 -5,-0.2 -0.772 360.0 75.1 -99.2 117.2 -14.9 4.4 -1.0 191 217 A G - 0 0 7 -2,-0.6 -183,-2.1 -7,-0.2 2,-0.3 -0.723 43.7-161.9 157.4 153.5 -17.8 5.8 1.1 192 218 A Q E -AC 7 183A 16 -9,-2.7 -9,-1.1 -185,-0.3 2,-0.4 -0.925 9.5-161.5-161.0 128.7 -20.0 8.8 1.7 193 219 A I E -AC 6 182A 0 -187,-3.2 -187,-2.8 -2,-0.3 2,-0.5 -0.910 15.6-156.7-101.0 141.1 -22.3 10.4 4.2 194 220 A V E -AC 5 181A 0 -13,-1.6 -13,-2.0 -2,-0.4 2,-0.7 -0.982 6.0-147.8-114.0 131.8 -24.7 13.1 3.0 195 221 A L E S+ C 0 180A 5 -191,-2.9 -191,-0.3 -2,-0.5 -15,-0.2 -0.890 82.6 5.0 -97.7 114.6 -26.1 15.6 5.5 196 222 A G S S+ 0 0 9 -17,-1.7 -19,-0.7 -2,-0.7 2,-0.3 0.575 126.3 30.1 94.4 14.2 -29.6 16.8 4.7 197 223 A G S S- 0 0 12 -3,-0.3 2,-0.4 -193,-0.1 -16,-0.4 -0.988 73.5-103.1-174.6 178.1 -30.2 14.5 1.7 198 224 A S - 0 0 16 -2,-0.3 5,-0.1 -18,-0.1 140,-0.1 -0.998 35.6-123.0-122.3 131.5 -29.7 11.3 -0.2 199 225 A D > - 0 0 8 -2,-0.4 3,-1.0 1,-0.2 -5,-0.0 -0.643 16.3-158.2 -74.2 113.4 -27.4 11.2 -3.2 200 226 A P G > S+ 0 0 63 0, 0.0 3,-1.0 0, 0.0 -1,-0.2 0.713 88.6 65.4 -64.1 -24.2 -29.5 10.0 -6.2 201 227 A Q G 3 S+ 0 0 130 1,-0.2 -2,-0.0 3,-0.0 0, 0.0 0.787 101.2 50.7 -68.7 -26.9 -26.4 8.8 -8.1 202 228 A H G < S+ 0 0 42 -3,-1.0 150,-0.8 149,-0.1 2,-0.3 0.116 112.1 42.1-103.8 20.9 -25.7 6.2 -5.3 203 229 A Y E < -D 351 0A 50 -3,-1.0 2,-0.3 148,-0.2 148,-0.2 -0.986 60.3-155.2-153.4 164.3 -29.2 4.5 -5.2 204 230 A E E +D 350 0A 99 146,-2.2 146,-0.8 -2,-0.3 2,-0.1 -0.970 57.1 15.2-139.3 156.6 -31.9 3.3 -7.5 205 231 A G E S- 0 0 55 -2,-0.3 2,-0.3 144,-0.1 -2,-0.0 -0.430 98.5 -44.0 76.4-158.3 -35.6 2.8 -7.2 206 232 A N E - 0 0 132 -2,-0.1 144,-0.2 1,-0.0 -2,-0.1 -0.810 51.5-112.8-114.4 146.4 -37.6 4.2 -4.3 207 233 A F E - 0 0 29 -2,-0.3 2,-0.4 142,-0.1 142,-0.2 -0.391 25.5-159.3 -69.6 151.3 -37.0 4.4 -0.6 208 234 A H E -D 348 0A 82 140,-1.3 140,-2.0 -2,-0.1 2,-0.3 -0.998 13.0-144.8-135.0 138.2 -39.2 2.4 1.8 209 235 A Y E -D 347 0A 68 -2,-0.4 2,-0.4 138,-0.2 82,-0.3 -0.699 18.4-169.2-116.0 151.8 -39.5 3.4 5.5 210 236 A I E -D 346 0A 17 136,-2.1 136,-2.0 -2,-0.3 3,-0.1 -0.976 29.8-125.8-133.7 120.4 -39.9 1.7 8.9 211 237 A N E -D 345 0A 109 -2,-0.4 10,-0.5 134,-0.2 134,-0.3 -0.340 32.8-103.2 -64.4 143.1 -40.7 3.9 11.9 212 238 A L - 0 0 21 132,-1.8 8,-0.2 1,-0.1 -1,-0.1 -0.463 26.0-142.8 -64.9 138.4 -38.3 3.6 14.9 213 239 A I S S+ 0 0 74 6,-1.3 2,-0.3 -2,-0.1 -1,-0.1 0.619 76.0 35.4 -84.4 -11.5 -40.0 1.5 17.6 214 240 A K S > S- 0 0 73 5,-0.4 3,-0.9 3,-0.3 5,-0.3 -0.998 87.0-101.2-149.7 150.3 -38.7 3.4 20.6 215 241 A T T 3 S+ 0 0 119 -2,-0.3 2,-0.1 1,-0.2 -1,-0.1 0.706 102.1 19.3 -33.2 -62.5 -37.9 7.0 21.6 216 242 A G T 3 S+ 0 0 2 -62,-0.1 -62,-0.4 -61,-0.1 2,-0.3 -0.332 100.3 72.1-127.3 50.9 -34.1 7.4 21.3 217 243 A V S < S- 0 0 17 -3,-0.9 2,-2.2 2,-0.2 -3,-0.3 -0.976 74.9-115.2-158.4 145.8 -32.3 4.8 19.2 218 244 A W S S+ 0 0 3 -157,-0.4 24,-2.3 -2,-0.3 2,-0.3 -0.461 73.7 126.2 -78.9 68.6 -31.9 3.9 15.5 219 245 A Q E -O 241 0E 0 -2,-2.2 -6,-1.3 -5,-0.3 -5,-0.4 -0.950 35.8-175.4-129.6 147.5 -33.6 0.6 16.0 220 246 A I E -O 240 0E 0 20,-2.0 20,-2.5 -2,-0.3 2,-0.4 -0.925 32.3 -92.1-141.8 162.9 -36.6 -0.9 14.2 221 247 A Q E -O 239 0E 76 -10,-0.5 69,-0.6 -2,-0.3 2,-0.5 -0.630 33.1-160.6 -78.6 128.3 -39.0 -3.9 14.2 222 248 A M E -OP 238 289E 0 16,-3.4 16,-2.3 -2,-0.4 67,-0.2 -0.955 5.1-160.4-110.2 129.7 -37.9 -6.8 12.0 223 249 A K E - 0 0 112 65,-3.0 2,-0.2 -2,-0.5 14,-0.2 0.635 64.1 -21.4 -87.5 -16.9 -40.7 -9.3 11.1 224 250 A G E - P 0 288E 3 64,-0.7 64,-2.6 12,-0.1 2,-0.6 -0.817 46.7-127.6 172.3 146.4 -38.6 -12.3 10.1 225 251 A V E -QP 233 287E 5 8,-2.5 7,-2.2 -2,-0.2 8,-0.9 -0.942 31.8-158.8-109.8 117.3 -35.3 -13.6 8.9 226 252 A S E -QP 231 286E 11 60,-3.0 60,-2.4 -2,-0.6 2,-0.5 -0.828 10.9-165.5-106.8 128.5 -35.6 -15.8 5.8 227 253 A V E > S-QP 230 285E 15 3,-1.9 3,-1.3 -2,-0.5 2,-0.9 -0.959 72.7 -33.1-110.7 119.3 -33.0 -18.4 4.6 228 254 A G T 3 S- 0 0 43 56,-2.7 -2,-0.1 -2,-0.5 3,-0.0 -0.648 127.0 -30.9 73.5-105.7 -33.6 -19.6 1.0 229 255 A S T 3 S+ 0 0 122 -2,-0.9 2,-0.4 1,-0.1 -1,-0.2 0.548 123.8 71.4-116.7 -17.0 -37.4 -19.4 0.6 230 256 A S E < S-Q 227 0E 74 -3,-1.3 -3,-1.9 -5,-0.0 2,-0.3 -0.848 80.5-113.3-116.1 141.1 -38.6 -20.2 4.2 231 257 A T E +Q 226 0E 80 -2,-0.4 -5,-0.2 -5,-0.2 3,-0.1 -0.532 33.3 175.1 -72.5 126.2 -38.5 -18.1 7.4 232 258 A L E + 0 0 42 -7,-2.2 2,-0.2 -2,-0.3 3,-0.2 0.908 57.1 8.7 -97.2 -62.3 -36.2 -19.6 10.0 233 259 A L E S+Q 225 0E 43 -8,-0.9 -8,-2.5 1,-0.2 -1,-0.3 -0.761 103.3 49.4-124.2 169.0 -36.0 -17.3 13.1 234 260 A b + 0 0 12 -2,-0.2 3,-0.3 -10,-0.2 4,-0.2 0.908 61.3 154.7 68.4 47.2 -37.6 -14.1 14.3 235 261 A E S S+ 0 0 114 1,-0.2 3,-0.1 -3,-0.2 -2,-0.1 0.914 73.4 36.1 -70.7 -43.9 -41.1 -15.6 13.7 236 262 A D S S- 0 0 165 1,-0.2 -1,-0.2 -12,-0.0 -12,-0.1 0.316 129.0 -82.8 -94.6 6.6 -42.9 -13.5 16.3 237 263 A G - 0 0 32 -3,-0.3 2,-0.2 -14,-0.2 -14,-0.2 0.365 46.4-167.3 101.3 130.7 -40.8 -10.3 15.7 238 264 A b E -O 222 0E 24 -16,-2.3 -16,-3.4 -4,-0.2 2,-0.2 -0.804 27.0 -93.5-136.7 179.5 -37.4 -9.1 16.8 239 265 A L E -O 221 0E 29 84,-0.4 86,-2.2 -2,-0.2 2,-0.4 -0.635 22.4-157.2-100.6 155.7 -35.4 -5.8 16.8 240 266 A A E -Or 220 325E 0 -20,-2.5 -20,-2.0 -2,-0.2 2,-0.6 -0.934 4.8-158.2-135.5 111.5 -32.9 -4.5 14.3 241 267 A L E -Or 219 326E 16 84,-2.4 86,-1.4 -2,-0.4 2,-0.9 -0.791 11.3-146.2 -90.3 118.4 -30.3 -1.9 15.2 242 268 A V E + r 0 327E 0 -24,-2.3 2,-0.6 -2,-0.6 86,-0.2 -0.763 27.0 178.3 -86.4 105.5 -28.9 0.0 12.3 243 269 A D > - 0 0 11 84,-1.6 3,-1.2 -2,-0.9 86,-0.3 -0.890 25.9-174.2-122.2 104.6 -25.4 0.7 13.4 244 270 A T T 3 S+ 0 0 8 -2,-0.6 -185,-0.1 1,-0.3 -1,-0.1 0.730 88.8 62.0 -68.2 -22.1 -22.9 2.5 11.1 245 271 A G T 3 S+ 0 0 3 -187,-0.1 2,-0.3 -205,-0.1 -1,-0.3 0.686 92.8 77.1 -75.4 -21.7 -20.1 1.8 13.6 246 272 A A < - 0 0 25 -3,-1.2 83,-2.5 81,-0.2 4,-0.0 -0.707 63.9-161.6 -88.5 145.1 -20.6 -1.9 13.2 247 273 A S + 0 0 11 -2,-0.3 83,-1.2 81,-0.3 2,-0.2 0.700 68.1 40.0 -97.7 -26.4 -19.1 -3.6 10.1 248 274 A Y S S- 0 0 44 81,-0.2 80,-0.4 82,-0.1 2,-0.3 -0.602 86.2 -96.0-117.2 175.1 -21.0 -6.9 10.0 249 275 A I E -s 312 0E 3 62,-1.7 64,-2.1 -2,-0.2 2,-0.3 -0.744 46.7-177.9 -86.1 143.3 -24.5 -8.3 10.7 250 276 A S E +sT 313 326E 12 76,-1.0 76,-2.2 -2,-0.3 2,-0.2 -0.986 12.0 169.7-143.8 153.4 -25.0 -9.6 14.2 251 277 A G E -s 314 0E 0 62,-1.0 64,-3.0 -2,-0.3 74,-0.1 -0.833 47.8 -61.0-144.6-176.9 -27.7 -11.4 16.2 252 278 A S > - 0 0 34 -2,-0.2 4,-2.6 62,-0.2 3,-0.5 -0.480 48.7-118.6 -69.3 144.1 -28.2 -13.2 19.5 253 279 A T H > S+ 0 0 52 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.871 115.4 60.4 -52.8 -39.4 -26.1 -16.3 19.9 254 280 A S H > S+ 0 0 89 1,-0.2 4,-1.1 2,-0.2 -1,-0.2 0.943 113.3 36.2 -48.2 -53.0 -29.3 -18.3 20.2 255 281 A S H > S+ 0 0 6 -3,-0.5 4,-2.0 1,-0.2 -2,-0.2 0.831 113.0 56.7 -74.1 -35.2 -30.4 -17.1 16.7 256 282 A I H X S+ 0 0 0 -4,-2.6 4,-2.0 2,-0.2 5,-0.2 0.843 101.4 57.4 -71.0 -34.3 -26.9 -17.1 15.1 257 283 A E H X S+ 0 0 124 -4,-2.3 4,-1.8 -5,-0.2 -1,-0.2 0.965 108.6 47.5 -53.5 -53.3 -26.4 -20.8 15.9 258 284 A K H X S+ 0 0 87 -4,-1.1 4,-1.9 -5,-0.2 3,-0.3 0.932 109.5 52.3 -55.4 -53.1 -29.6 -21.6 14.0 259 285 A L H X S+ 0 0 9 -4,-2.0 4,-1.5 1,-0.2 -1,-0.2 0.890 111.6 45.5 -51.8 -48.6 -28.7 -19.5 10.9 260 286 A M H X>S+ 0 0 3 -4,-2.0 5,-2.1 2,-0.2 4,-1.3 0.778 106.6 58.5 -73.2 -28.6 -25.3 -21.1 10.4 261 287 A E H <5S+ 0 0 159 -4,-1.8 3,-0.4 -3,-0.3 -1,-0.2 0.946 107.9 46.9 -63.0 -47.8 -26.5 -24.6 10.9 262 288 A A H <5S+ 0 0 55 -4,-1.9 -2,-0.2 1,-0.2 -1,-0.2 0.850 112.8 50.0 -61.8 -36.8 -28.9 -24.1 7.9 263 289 A L H <5S- 0 0 10 -4,-1.5 -1,-0.2 -5,-0.2 -2,-0.2 0.731 107.2-130.6 -71.0 -24.7 -26.1 -22.6 5.9 264 290 A G T <5 + 0 0 43 -4,-1.3 2,-0.8 -3,-0.4 -3,-0.2 0.828 52.9 152.4 73.4 33.1 -23.9 -25.6 6.8 265 291 A A < - 0 0 7 -5,-2.1 -1,-0.2 9,-0.1 9,-0.2 -0.853 40.4-138.9 -98.4 102.1 -21.0 -23.3 7.8 266 292 A K - 0 0 160 -2,-0.8 7,-1.6 -3,-0.1 2,-0.3 -0.255 27.3-108.1 -57.8 146.4 -19.0 -25.1 10.4 267 293 A K B -V 272 0F 122 5,-0.2 2,-0.4 2,-0.0 5,-0.2 -0.593 22.8-162.0 -86.4 138.3 -17.9 -22.9 13.3 268 294 A R - 0 0 109 3,-2.3 0, 0.0 -2,-0.3 0, 0.0 -0.920 33.2-121.0-104.0 143.7 -14.4 -21.5 14.1 269 295 A L S S+ 0 0 171 -2,-0.4 3,-0.1 1,-0.2 -1,-0.1 0.798 114.2 41.5 -56.9 -26.6 -14.0 -20.3 17.7 270 296 A F S S- 0 0 56 1,-0.1 -1,-0.2 -3,-0.0 2,-0.2 0.963 130.9 -19.1 -80.4 -63.6 -13.1 -16.9 16.2 271 297 A D S S- 0 0 10 42,-0.1 -3,-2.3 40,-0.0 2,-0.5 -0.574 74.3 -85.7-129.9-172.0 -15.6 -16.5 13.3 272 298 A Y B -V 267 0F 19 40,-0.4 38,-2.0 38,-0.2 2,-0.3 -0.941 49.6-173.9-105.0 133.5 -17.9 -18.6 11.1 273 299 A V E -W 309 0G 22 -7,-1.6 2,-0.3 -2,-0.5 36,-0.2 -0.837 16.2-172.0-129.6 157.8 -16.3 -20.2 8.0 274 300 A V E -W 308 0G 10 34,-2.1 34,-0.7 -2,-0.3 2,-0.2 -0.954 40.4 -89.5-141.9 157.5 -17.1 -22.1 4.9 275 301 A K > - 0 0 85 -2,-0.3 4,-1.6 1,-0.1 31,-0.2 -0.544 35.8-127.4 -69.5 136.1 -15.0 -23.8 2.2 276 302 A c T 4 S+ 0 0 44 29,-1.1 -1,-0.1 1,-0.2 30,-0.1 0.716 109.4 51.5 -62.5 -25.3 -14.2 -21.4 -0.7 277 303 A N T 4 S+ 0 0 110 28,-0.3 4,-0.4 1,-0.1 -1,-0.2 0.931 112.3 45.2 -70.2 -48.0 -15.6 -23.8 -3.3 278 304 A E T >> S+ 0 0 96 1,-0.2 4,-0.8 2,-0.1 3,-0.6 0.675 94.6 85.5 -71.4 -19.3 -18.9 -24.3 -1.4 279 305 A G G >< S+ 0 0 2 -4,-1.6 3,-2.6 1,-0.2 -1,-0.2 0.926 82.8 50.5 -49.4 -68.6 -19.3 -20.5 -0.8 280 306 A P G 34 S+ 0 0 97 0, 0.0 -1,-0.2 0, 0.0 18,-0.2 0.741 105.0 61.7 -45.2 -30.8 -21.1 -19.4 -4.0 281 307 A T G <4 S+ 0 0 114 -3,-0.6 -2,-0.2 -4,-0.4 -3,-0.1 0.812 77.6 115.5 -64.3 -32.1 -23.6 -22.2 -3.5 282 308 A L S << S- 0 0 9 -3,-2.6 16,-0.4 -4,-0.8 -19,-0.1 -0.042 70.9-111.1 -48.2 139.6 -24.7 -20.7 -0.1 283 309 A P - 0 0 44 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.017 32.0 -89.9 -71.7 172.8 -28.4 -19.5 -0.2 284 310 A D - 0 0 66 13,-0.1 -56,-2.7 14,-0.0 2,-0.4 -0.626 32.9-148.5 -81.4 141.2 -29.8 -16.0 -0.1 285 311 A I E -PU 227 296E 3 11,-2.4 11,-3.9 -2,-0.3 2,-0.4 -0.895 14.9-168.2-105.1 142.1 -30.6 -14.4 3.2 286 312 A S E -PU 226 295E 13 -60,-2.4 -60,-3.0 -2,-0.4 2,-0.5 -0.990 12.1-149.1-139.2 129.0 -33.4 -12.0 3.4 287 313 A F E -PU 225 294E 4 7,-2.9 7,-3.0 -2,-0.4 2,-1.1 -0.836 13.7-140.9-100.9 127.6 -34.5 -9.6 6.2 288 314 A H E +PU 224 293E 52 -64,-2.6 -65,-3.0 -2,-0.5 -64,-0.7 -0.741 33.5 164.6 -93.4 96.7 -38.2 -8.7 6.6 289 315 A L E > -PU 222 292E 0 3,-1.4 3,-1.1 -2,-1.1 -67,-0.2 -0.963 57.2 -51.5-120.4 118.9 -38.3 -5.0 7.5 290 316 A G T 3 S- 0 0 15 -69,-0.6 -80,-0.1 -2,-0.5 -67,-0.1 -0.336 118.3 -15.1 56.9-125.3 -41.5 -3.1 7.2 291 317 A G T 3 S+ 0 0 75 -82,-0.3 -1,-0.2 -2,-0.1 2,-0.2 0.800 124.1 56.8 -80.9 -31.2 -43.1 -3.6 3.8 292 318 A K E < S-U 289 0E 112 -3,-1.1 -3,-1.4 -5,-0.0 2,-0.5 -0.607 73.8-121.9-111.3 161.7 -40.3 -5.0 1.8 293 319 A E E -U 288 0E 89 -2,-0.2 2,-0.8 -5,-0.2 -5,-0.2 -0.906 22.2-152.5-102.9 120.6 -37.9 -8.0 1.9 294 320 A Y E -U 287 0E 13 -7,-3.0 -7,-2.9 -2,-0.5 2,-0.2 -0.805 17.2-162.2-103.0 102.8 -34.2 -7.1 2.0 295 321 A T E -U 286 0E 42 -2,-0.8 2,-0.4 -9,-0.3 -9,-0.3 -0.502 14.5-165.4 -89.6 146.2 -32.1 -9.9 0.4 296 322 A L E -U 285 0E 4 -11,-3.9 -11,-2.4 -2,-0.2 5,-0.1 -0.948 15.5-152.0-129.8 113.5 -28.3 -10.5 0.7 297 323 A T >> - 0 0 43 -2,-0.4 4,-1.2 -13,-0.2 3,-0.8 -0.165 35.6 -94.8 -75.1 172.6 -26.8 -13.0 -1.8 298 324 A S H >> S+ 0 0 21 -16,-0.4 4,-2.1 1,-0.3 3,-0.5 0.908 125.8 56.5 -54.5 -44.7 -23.8 -15.2 -1.2 299 325 A A H 34 S+ 0 0 79 1,-0.2 -1,-0.3 2,-0.2 -20,-0.0 0.813 103.0 56.6 -55.6 -33.8 -21.6 -12.6 -2.9 300 326 A D H <4 S+ 0 0 40 -3,-0.8 -1,-0.2 1,-0.2 -2,-0.2 0.843 120.6 23.6 -72.3 -36.9 -22.8 -9.9 -0.4 301 327 A Y H << S+ 0 0 2 -4,-1.2 10,-2.8 -3,-0.5 2,-0.3 0.441 110.8 76.5-113.1 -2.4 -21.8 -11.7 2.8 302 328 A V B < X 310 0H 24 -4,-2.1 8,-0.2 8,-0.2 7,-0.1 -0.795 360.0 360.0-103.7 152.7 -19.0 -14.1 1.7 303 329 A F 0 0 138 6,-0.8 -24,-0.1 -2,-0.3 -3,-0.1 -0.959 360.0 360.0-113.5 360.0 -15.4 -13.1 0.9 304 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 305 336 A K 0 0 136 0, 0.0 -29,-1.1 0, 0.0 -28,-0.3 0.000 360.0 360.0 360.0 -37.4 -8.4 -23.7 -0.3 306 337 A K + 0 0 137 -31,-0.2 2,-0.9 -30,-0.1 -32,-0.1 0.339 360.0 102.3 -95.7 5.0 -10.7 -24.2 2.7 307 338 A L + 0 0 133 -32,-0.1 2,-0.3 -34,-0.1 -32,-0.1 -0.769 35.4 133.9-101.8 95.2 -10.3 -20.7 4.2 308 339 A c E -W 274 0G 20 -2,-0.9 -34,-2.1 -34,-0.7 2,-0.2 -0.821 33.2-160.8-143.8 105.1 -13.3 -18.4 3.5 309 340 A T E -W 273 0G 36 -2,-0.3 -6,-0.8 -36,-0.2 -36,-0.2 -0.547 11.4-133.3 -91.2 148.1 -14.8 -16.3 6.3 310 341 A L B -X 302 0H 2 -38,-2.0 -38,-0.2 -2,-0.2 -8,-0.2 -0.484 16.8-119.7 -99.2 166.2 -18.3 -14.7 6.3 311 342 A A S S+ 0 0 0 -10,-2.8 -62,-1.7 -2,-0.2 2,-0.4 -0.106 82.3 94.3 -96.9 34.8 -19.7 -11.3 7.2 312 343 A I E +s 249 0E 5 -40,-0.2 -40,-0.4 -64,-0.2 2,-0.2 -0.977 46.3 166.3-127.9 143.4 -22.0 -12.5 10.0 313 344 A H E -s 250 0E 28 -64,-2.1 -62,-1.0 -2,-0.4 2,-0.4 -0.823 32.7-105.8-144.0 175.3 -21.2 -12.7 13.8 314 345 A A E +s 251 0E 31 -2,-0.2 2,-0.3 -64,-0.2 -62,-0.2 -0.938 30.8 169.1-113.8 136.7 -22.9 -13.1 17.2 315 346 A M - 0 0 81 -64,-3.0 2,-1.8 -2,-0.4 9,-0.3 -0.776 22.5-154.9-147.9 99.3 -23.4 -10.3 19.7 316 347 A D - 0 0 102 -2,-0.3 -64,-0.1 -64,-0.1 9,-0.1 -0.567 25.2-156.8 -72.4 85.9 -25.6 -10.9 22.8 317 348 A I - 0 0 47 -2,-1.8 7,-0.1 7,-0.4 -2,-0.1 -0.500 21.7-102.7 -71.5 132.6 -26.5 -7.2 23.3 318 349 A P > - 0 0 75 0, 0.0 4,-1.2 0, 0.0 3,-0.1 0.059 36.5 -97.1 -54.7 165.7 -27.6 -6.3 26.9 319 350 A P T 4 S+ 0 0 109 0, 0.0 -2,-0.1 0, 0.0 0, 0.0 0.483 107.9 68.5 -76.2 -9.8 -31.3 -5.9 27.9 320 351 A P T 4 S+ 0 0 104 0, 0.0 -3,-0.0 0, 0.0 0, 0.0 0.993 120.0 23.0 -65.8 -66.9 -31.8 -2.1 27.7 321 352 A T T 4 S- 0 0 24 1,-0.1 -4,-0.1 -3,-0.1 -104,-0.0 0.714 124.2-151.1 -63.1 -22.8 -31.5 -1.8 23.9 322 353 A G < - 0 0 6 -4,-1.2 2,-0.3 2,-0.1 -1,-0.1 0.031 31.3 -28.4 92.1 173.2 -32.5 -5.4 24.4 323 354 A P S S+ 0 0 102 0, 0.0 -84,-0.4 0, 0.0 2,-0.3 -0.558 87.1 150.6 -58.0 124.2 -31.9 -8.7 22.6 324 355 A T - 0 0 3 -2,-0.3 -7,-0.4 -9,-0.3 -84,-0.2 -0.989 47.0-117.7-157.2 160.4 -31.5 -7.3 19.0 325 356 A W E -r 240 0E 15 -86,-2.2 -84,-2.4 -2,-0.3 2,-0.3 -0.475 26.3-139.0 -91.2 171.6 -29.9 -7.8 15.7 326 357 A A E -rT 241 250E 6 -76,-2.2 2,-1.2 -86,-0.2 -76,-1.0 -0.843 4.2-156.2-141.9 100.3 -27.4 -5.3 14.2 327 358 A L E +r 242 0E 1 -86,-1.4 -84,-1.6 -2,-0.3 -78,-0.2 -0.665 32.6 179.6 -71.3 99.2 -27.5 -4.2 10.5 328 359 A G >> - 0 0 0 -2,-1.2 4,-1.5 -80,-0.4 3,-1.3 -0.049 47.1 -63.3 -89.2-162.8 -23.9 -3.1 10.2 329 360 A A H 3> S+ 0 0 7 -83,-2.5 4,-1.8 -86,-0.3 -81,-0.2 0.746 126.2 65.1 -57.1 -30.6 -21.9 -1.7 7.2 330 361 A T H 3> S+ 0 0 8 -83,-1.2 4,-0.7 2,-0.2 -1,-0.3 0.841 105.1 43.9 -64.9 -36.1 -22.3 -4.9 5.2 331 362 A F H X> S+ 0 0 0 -3,-1.3 4,-2.2 2,-0.2 3,-0.8 0.928 113.3 51.3 -69.6 -47.5 -26.0 -4.5 4.9 332 363 A I H 3< S+ 0 0 0 -4,-1.5 -148,-0.5 1,-0.3 -2,-0.2 0.739 98.4 66.6 -64.5 -27.5 -25.7 -0.8 4.1 333 364 A R H 3< S+ 0 0 45 -4,-1.8 -1,-0.3 1,-0.2 3,-0.2 0.893 114.2 29.7 -62.1 -40.1 -23.2 -1.5 1.4 334 365 A K H << S+ 0 0 30 -3,-0.8 17,-2.3 -4,-0.7 2,-0.6 0.758 125.7 49.6 -86.5 -29.7 -26.0 -3.2 -0.6 335 366 A F E < S- E 0 350A 13 -4,-2.2 15,-0.2 15,-0.2 -1,-0.2 -0.851 81.1-139.7-121.0 96.0 -28.8 -1.1 0.8 336 367 A Y E - E 0 349A 2 13,-1.1 13,-2.1 -2,-0.6 2,-0.4 -0.259 28.7-150.8 -48.9 129.7 -28.4 2.7 0.7 337 368 A T E -BE 182 348A 0 -155,-1.4 -155,-2.0 11,-0.2 2,-0.4 -0.893 16.2-162.7-120.9 138.0 -29.8 3.9 4.0 338 369 A E E -BE 181 347A 17 9,-2.9 9,-2.4 -2,-0.4 2,-0.8 -0.982 10.9-149.9-118.7 129.8 -31.4 7.2 5.1 339 370 A F E -BE 180 346A 0 -159,-3.8 -159,-1.4 -2,-0.4 2,-1.1 -0.869 14.0-163.4 -99.6 106.0 -31.7 8.2 8.7 340 371 A D E >> +BE 179 345A 5 5,-2.6 5,-1.9 -2,-0.8 4,-0.7 -0.701 20.3 166.5 -99.2 87.9 -34.9 10.3 8.9 341 372 A R T 45S+ 0 0 61 -2,-1.1 -162,-0.2 -163,-0.7 -1,-0.2 0.840 73.7 63.2 -70.6 -33.2 -34.8 12.2 12.2 342 373 A R T 45S+ 0 0 172 -164,-1.9 -1,-0.2 1,-0.2 -163,-0.1 0.859 121.6 21.6 -56.3 -41.2 -37.6 14.6 11.1 343 374 A N T 45S- 0 0 83 -3,-0.3 -1,-0.2 -165,-0.2 -2,-0.2 0.323 106.8-122.9-108.5 2.8 -40.0 11.7 10.9 344 375 A N T <5S+ 0 0 61 -4,-0.7 -132,-1.8 1,-0.2 2,-0.3 0.966 70.8 112.6 45.2 67.9 -38.1 9.4 13.2 345 376 A R E < -DE 211 340A 70 -5,-1.9 -5,-2.6 -134,-0.3 2,-0.4 -0.961 61.1-127.3-153.4 163.2 -37.8 6.5 10.7 346 377 A I E -DE 210 339A 0 -136,-2.0 -136,-2.1 -2,-0.3 2,-0.4 -0.965 22.9-161.7-117.2 139.9 -35.1 4.7 8.7 347 378 A G E -DE 209 338A 0 -9,-2.4 -9,-2.9 -2,-0.4 2,-0.3 -0.954 1.7-159.8-126.0 141.9 -35.4 4.2 4.9 348 379 A F E +DE 208 337A 1 -140,-2.0 -140,-1.3 -2,-0.4 2,-0.3 -0.895 12.7 168.1-122.8 147.9 -33.7 1.8 2.5 349 380 A A E - E 0 336A 5 -13,-2.1 -13,-1.1 -2,-0.3 2,-0.2 -0.971 45.1 -85.7-148.1 161.3 -33.0 1.6 -1.2 350 381 A L E -DE 204 335A 68 -146,-0.8 -146,-2.2 -2,-0.3 -15,-0.2 -0.499 47.4-133.0 -69.1 133.7 -30.8 -0.5 -3.5 351 382 A A E D 203 0A 3 -17,-2.3 -148,-0.2 -148,-0.2 -149,-0.1 -0.458 360.0 360.0 -87.3 162.2 -27.3 1.0 -3.8 352 383 A R 0 0 145 -150,-0.8 -151,-0.0 -2,-0.1 -17,-0.0 -0.939 360.0 360.0-157.2 360.0 -25.3 1.5 -7.0