==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=13-MAY-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 03-MAY-12 4AST . COMPND 2 MOLECULE: ALDO-KETO REDUCTASE AKR14A1; . SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI; . AUTHOR X.ZHU,E.M.ELLIS,A.LAPTHORN . 2446 16 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 88250.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 1783 72.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 280 11.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 48 2.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 16 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 8 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 8 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 94 3.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 336 13.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 796 32.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 85 3.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 8 0 0 8 8 1 9 1 9 30 2 8 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 8 24 24 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A V 0 0 89 0, 0.0 2,-0.5 0, 0.0 82,-0.1 0.000 360.0 360.0 360.0 136.9 40.1 25.3 38.7 2 3 A W - 0 0 36 80,-0.2 2,-0.6 81,-0.1 1244,-0.0 -0.986 360.0-162.6-128.6 120.6 41.5 22.2 37.1 3 4 A L - 0 0 80 -2,-0.5 1243,-0.0 1242,-0.0 80,-0.0 -0.899 22.1-131.9-102.3 118.9 43.7 22.1 34.1 4 5 A A - 0 0 1 -2,-0.6 46,-0.1 1,-0.1 45,-0.0 -0.305 40.4 -82.9 -66.5 152.6 43.9 18.7 32.3 5 6 A N > - 0 0 58 1,-0.2 3,-1.7 2,-0.1 -1,-0.1 -0.399 34.3-144.9 -57.7 119.8 47.3 17.3 31.5 6 7 A P T 3 S+ 0 0 100 0, 0.0 3,-0.4 0, 0.0 -1,-0.2 0.720 98.9 55.7 -59.8 -19.6 48.4 18.9 28.1 7 8 A E T > S+ 0 0 141 1,-0.2 3,-2.4 2,-0.1 4,-0.4 0.284 72.6 114.9 -91.6 9.7 50.2 15.7 27.1 8 9 A R T < S+ 0 0 19 -3,-1.7 4,-0.5 1,-0.3 3,-0.3 0.724 75.9 47.4 -55.1 -26.9 47.0 13.6 27.5 9 10 A Y T 3 S+ 0 0 46 -3,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.349 91.8 85.0 -96.9 8.0 46.7 12.8 23.8 10 11 A G S < S+ 0 0 61 -3,-2.4 -1,-0.2 1,-0.1 -2,-0.1 0.758 99.9 21.0 -82.5 -24.8 50.3 11.8 23.4 11 12 A Q S S+ 0 0 171 -4,-0.4 -2,-0.1 -3,-0.3 -1,-0.1 0.766 94.2 97.8-113.9 -36.9 50.3 8.1 24.5 12 13 A M - 0 0 13 -4,-0.5 2,-0.4 42,-0.2 43,-0.1 -0.240 65.8-136.8 -58.2 138.7 46.7 6.8 24.2 13 14 A Q - 0 0 72 2,-0.0 13,-2.8 14,-0.0 2,-0.4 -0.851 17.6-157.6 -93.7 139.4 46.0 4.9 21.0 14 15 A Y E -A 25 0A 31 -2,-0.4 2,-0.4 11,-0.3 253,-0.1 -0.919 4.5-161.0-116.5 143.3 42.7 5.7 19.4 15 16 A R E -A 24 0A 36 9,-2.8 9,-2.4 -2,-0.4 2,-0.1 -0.986 24.8-111.4-126.3 141.9 40.8 3.5 17.0 16 17 A Y E -A 23 0A 77 -2,-0.4 2,-0.9 7,-0.3 7,-0.2 -0.383 34.2-123.6 -65.2 135.1 38.1 4.2 14.5 17 18 A C > - 0 0 0 5,-2.2 3,-1.7 200,-0.1 5,-0.3 -0.811 64.4 -59.5 -90.2 100.7 34.8 2.6 15.6 18 19 A G T 3 S- 0 0 33 -2,-0.9 198,-0.2 198,-0.3 197,-0.1 -0.188 111.3 -26.0 57.0-134.8 33.9 0.3 12.7 19 20 A K T 3 S+ 0 0 105 196,-2.0 -1,-0.3 195,-0.1 197,-0.1 0.489 114.7 106.7 -84.6 -0.4 33.5 2.3 9.4 20 21 A S S < S- 0 0 9 -3,-1.7 400,-0.1 195,-0.4 -3,-0.0 -0.102 77.7-122.1 -77.0 172.3 32.6 5.5 11.3 21 22 A G S S+ 0 0 5 432,-0.1 2,-0.6 -5,-0.1 399,-0.2 0.333 78.5 110.4 -94.5 7.1 34.7 8.6 11.8 22 23 A L - 0 0 0 -5,-0.3 -5,-2.2 167,-0.1 2,-0.6 -0.752 55.3-156.4 -91.3 120.8 34.5 8.4 15.6 23 24 A R E -A 16 0A 80 -2,-0.6 -7,-0.3 391,-0.3 -2,-0.1 -0.849 7.5-166.1-100.0 116.3 37.7 7.4 17.3 24 25 A L E -A 15 0A 0 -9,-2.4 -9,-2.8 -2,-0.6 2,-0.1 -0.705 30.1-104.6 -91.0 151.5 37.4 5.8 20.7 25 26 A P E -A 14 0A 0 0, 0.0 -11,-0.3 0, 0.0 243,-0.1 -0.503 29.9-118.2 -69.8 151.8 40.4 5.4 23.0 26 27 A A S S+ 0 0 0 -13,-2.8 242,-2.1 241,-0.2 2,-0.5 0.811 107.0 43.4 -62.4 -31.5 41.7 1.8 23.1 27 28 A L E S-b 268 0B 0 -14,-0.3 2,-0.3 240,-0.2 31,-0.3 -0.972 75.3-174.3-114.0 129.0 40.8 1.8 26.8 28 29 A S E -b 269 0B 0 240,-3.0 242,-2.7 -2,-0.5 2,-0.5 -0.893 23.9-121.3-116.0 154.0 37.5 3.3 27.9 29 30 A L E -bc 270 59B 0 29,-2.2 31,-2.5 -2,-0.3 2,-0.4 -0.829 21.4-158.9-100.4 122.7 36.3 3.8 31.5 30 31 A G E - c 0 60B 10 240,-2.8 242,-0.3 -2,-0.5 3,-0.3 -0.800 9.7-153.9 -94.5 145.0 33.1 2.1 32.5 31 32 A L + 0 0 0 29,-2.3 4,-0.4 -2,-0.4 31,-0.1 -0.016 57.4 121.8-109.1 24.8 31.2 3.5 35.5 32 33 A W S S+ 0 0 90 28,-0.2 34,-0.8 33,-0.1 2,-0.3 0.903 80.3 20.2 -52.6 -44.6 29.5 0.2 36.4 33 34 A H S S+ 0 0 96 -3,-0.3 239,-0.4 32,-0.1 -1,-0.1 -0.868 114.3 30.9-126.7 158.9 31.1 0.2 39.8 34 35 A N S S+ 0 0 44 -2,-0.3 -1,-0.1 32,-0.3 -2,-0.1 0.432 95.0 85.1 79.9 3.5 32.6 2.8 42.2 35 36 A F + 0 0 0 31,-0.5 40,-0.3 -4,-0.4 41,-0.2 0.156 64.5 107.5-121.4 20.9 30.5 5.7 41.1 36 37 A G S > S- 0 0 0 30,-0.5 3,-1.5 39,-0.1 939,-0.2 -0.230 87.9 -97.4 -86.5 178.9 27.5 5.3 43.2 37 38 A H T 3 S+ 0 0 6 30,-0.8 939,-1.9 1,-0.3 938,-0.4 0.625 121.0 68.6 -74.1 -7.9 26.2 7.2 46.2 38 39 A V T 3 S+ 0 0 76 29,-1.2 2,-0.3 937,-0.2 -1,-0.3 0.593 94.1 69.7 -80.6 -11.4 27.8 4.4 48.3 39 40 A N S < S- 0 0 46 -3,-1.5 936,-0.5 28,-0.2 2,-0.1 -0.862 95.0-102.5-109.8 145.9 31.3 5.7 47.2 40 41 A A >> - 0 0 19 -2,-0.3 4,-1.7 932,-0.2 3,-0.7 -0.398 22.5-134.3 -68.0 133.8 32.9 9.0 48.2 41 42 A L H 3> S+ 0 0 12 932,-0.5 4,-3.0 930,-0.3 931,-0.2 0.808 101.8 62.6 -57.9 -31.0 32.8 11.7 45.5 42 43 A E H 3> S+ 0 0 57 929,-2.1 4,-2.1 2,-0.2 -1,-0.2 0.876 103.4 47.4 -68.9 -34.1 36.4 12.6 46.0 43 44 A S H <> S+ 0 0 59 -3,-0.7 4,-1.9 928,-0.3 -1,-0.2 0.932 112.3 50.4 -66.1 -45.6 37.6 9.2 44.9 44 45 A Q H X S+ 0 0 2 -4,-1.7 4,-2.3 1,-0.2 5,-0.2 0.928 108.8 52.5 -57.2 -46.2 35.3 9.4 42.0 45 46 A R H X S+ 0 0 20 -4,-3.0 4,-2.4 1,-0.2 -1,-0.2 0.916 107.6 50.6 -56.0 -48.8 36.7 12.8 41.1 46 47 A A H X S+ 0 0 45 -4,-2.1 4,-2.3 1,-0.2 -1,-0.2 0.876 109.7 52.0 -56.5 -40.7 40.3 11.6 41.1 47 48 A I H X S+ 0 0 1 -4,-1.9 4,-3.0 2,-0.2 -2,-0.2 0.951 110.1 46.2 -65.9 -48.5 39.4 8.7 38.8 48 49 A L H X S+ 0 0 1 -4,-2.3 4,-2.4 1,-0.2 5,-0.2 0.936 114.4 47.9 -62.6 -42.7 37.7 10.9 36.2 49 50 A R H X S+ 0 0 70 -4,-2.4 4,-2.3 -5,-0.2 -1,-0.2 0.914 114.2 46.4 -62.6 -44.8 40.6 13.4 36.2 50 51 A K H X S+ 0 0 54 -4,-2.3 4,-1.5 -5,-0.2 6,-0.2 0.924 109.8 53.7 -65.0 -43.4 43.2 10.7 35.9 51 52 A A H ><>S+ 0 0 0 -4,-3.0 5,-2.3 1,-0.2 3,-0.8 0.942 112.2 43.8 -53.8 -52.7 41.4 8.9 33.2 52 53 A F H ><5S+ 0 0 0 -4,-2.4 3,-1.4 1,-0.3 -1,-0.2 0.875 109.0 57.6 -67.7 -32.8 41.1 12.0 31.1 53 54 A D H 3<5S+ 0 0 35 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.2 0.761 104.5 52.7 -65.0 -25.2 44.8 12.9 31.8 54 55 A L T <<5S- 0 0 31 -4,-1.5 -1,-0.3 -3,-0.8 -2,-0.2 0.404 126.4-102.2 -90.4 1.4 45.7 9.4 30.4 55 56 A G T < 5S+ 0 0 0 -3,-1.4 2,-0.9 1,-0.3 -3,-0.2 0.531 72.5 147.3 90.2 8.5 43.8 10.2 27.2 56 57 A I < + 0 0 0 -5,-2.3 -1,-0.3 -6,-0.2 -2,-0.1 -0.701 14.2 168.7 -75.4 108.2 40.7 8.2 28.0 57 58 A T + 0 0 0 -2,-0.9 35,-3.0 -30,-0.2 2,-0.5 0.382 47.8 82.1-103.7 1.4 38.0 10.2 26.4 58 59 A H E - d 0 92B 0 -31,-0.3 -29,-2.2 33,-0.2 2,-0.5 -0.944 50.1-177.3-121.2 124.2 35.2 7.7 26.6 59 60 A F E -cd 29 93B 1 33,-2.3 35,-1.8 -2,-0.5 2,-0.5 -0.986 13.1-155.6-123.9 121.4 33.0 7.2 29.7 60 61 A D E +cd 30 94B 1 -31,-2.5 -29,-2.3 -2,-0.5 2,-0.2 -0.900 20.9 165.0-110.7 118.6 30.4 4.5 29.5 61 62 A L - 0 0 0 33,-1.8 2,-0.3 -2,-0.5 -29,-0.1 -0.571 18.1-158.6-119.4-179.7 27.3 4.7 31.8 62 63 A A > - 0 0 0 33,-0.2 3,-1.5 -2,-0.2 8,-0.3 -0.944 35.2-107.3-154.0 158.1 23.9 3.1 32.0 63 64 A N T 3 S+ 0 0 0 33,-2.0 7,-0.9 -2,-0.3 10,-0.2 0.905 116.8 46.0 -52.3 -42.5 20.7 4.1 33.7 64 65 A N T 3 S+ 0 0 46 5,-0.2 -1,-0.3 32,-0.2 7,-0.1 0.449 80.8 124.6 -90.2 3.3 21.0 1.6 36.4 65 66 A Y < > + 0 0 6 -3,-1.5 7,-1.8 4,-0.1 5,-0.8 -0.366 53.0 41.0 -64.5 138.8 24.7 2.1 37.4 66 67 A G T 5S- 0 0 5 -34,-0.8 -31,-0.5 5,-0.2 -30,-0.5 -0.713 95.1 -79.2-179.1-126.1 25.4 2.8 41.0 67 68 A P T 5S+ 0 0 73 0, 0.0 -29,-1.2 0, 0.0 -30,-0.8 0.538 124.1 40.2 -92.7 161.0 24.2 1.7 43.5 68 69 A P T > 5S- 0 0 45 0, 0.0 3,-2.5 0, 0.0 4,-0.4 0.625 114.0 -96.0 -82.0 172.3 21.6 3.0 43.9 69 70 A P T 3 5S+ 0 0 77 0, 0.0 -5,-0.2 0, 0.0 -3,-0.2 -0.194 107.9 16.8 -56.6 136.8 20.3 3.1 40.3 70 71 A G T 3> S+ 0 0 1 -3,-2.5 4,-3.2 1,-0.2 5,-0.3 0.831 72.7 55.9 -71.3 -34.1 23.6 7.5 41.0 72 73 A A H > S+ 0 0 0 -7,-1.8 4,-2.7 -4,-0.4 -1,-0.2 0.928 110.5 47.7 -59.9 -42.1 26.6 7.0 38.7 73 74 A E H > S+ 0 0 0 -8,-0.5 4,-2.6 -11,-0.2 -2,-0.2 0.948 113.0 47.5 -65.9 -46.5 24.9 9.2 36.2 74 75 A E H X S+ 0 0 39 -4,-2.2 4,-2.0 2,-0.2 -2,-0.2 0.934 115.3 45.4 -57.9 -47.4 24.1 11.9 38.8 75 76 A N H X S+ 0 0 9 -4,-3.2 4,-2.6 -40,-0.3 5,-0.2 0.916 112.7 50.2 -66.1 -39.3 27.7 11.8 40.2 76 77 A F H X S+ 0 0 1 -4,-2.7 4,-2.7 -5,-0.3 -1,-0.2 0.917 109.3 52.7 -62.7 -41.2 29.1 11.9 36.8 77 78 A G H X S+ 0 0 2 -4,-2.6 4,-1.9 2,-0.2 -1,-0.2 0.870 109.0 49.3 -61.8 -40.5 27.0 14.8 35.9 78 79 A R H X S+ 0 0 20 -4,-2.0 4,-1.7 2,-0.2 -2,-0.2 0.944 113.4 44.9 -67.0 -44.7 28.2 16.7 39.0 79 80 A L H X>S+ 0 0 0 -4,-2.6 4,-2.9 1,-0.2 5,-0.8 0.887 110.7 56.3 -68.9 -33.3 31.8 16.1 38.2 80 81 A L H X5S+ 0 0 13 -4,-2.7 4,-1.4 -5,-0.2 -1,-0.2 0.929 110.0 44.6 -57.8 -46.2 31.2 17.0 34.6 81 82 A R H <5S+ 0 0 148 -4,-1.9 4,-0.2 -5,-0.2 -1,-0.2 0.808 119.7 40.9 -73.0 -32.6 29.9 20.3 35.5 82 83 A E H <5S+ 0 0 72 -4,-1.7 -2,-0.2 -5,-0.1 -80,-0.2 0.925 133.3 14.4 -81.8 -46.3 32.6 21.1 38.1 83 84 A D H <5S+ 0 0 21 -4,-2.9 -3,-0.2 -5,-0.2 -2,-0.2 0.607 128.7 43.4-108.7 -15.9 35.8 19.8 36.3 84 85 A F >X< + 0 0 2 -4,-1.4 3,-1.9 -5,-0.8 4,-0.9 0.198 65.3 116.3-122.5 17.0 34.8 19.3 32.7 85 86 A A G >4 S+ 0 0 83 1,-0.3 3,-0.6 -4,-0.2 -1,-0.1 0.923 89.2 41.6 -49.9 -42.6 32.8 22.3 31.7 86 87 A A G 34 S+ 0 0 65 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.1 0.476 117.9 48.8 -81.9 -4.4 35.5 23.2 29.2 87 88 A Y G X4 + 0 0 14 -3,-1.9 3,-2.2 -7,-0.2 -1,-0.2 0.392 69.8 106.0-123.1 3.6 36.1 19.6 28.0 88 89 A R G X< S+ 0 0 32 -4,-0.9 3,-1.7 -3,-0.6 -2,-0.1 0.830 80.9 55.6 -58.7 -36.7 32.7 18.1 27.3 89 90 A D G 3 S+ 0 0 36 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.1 0.504 102.0 58.5 -80.0 -1.0 33.2 18.3 23.5 90 91 A E G < S+ 0 0 12 -3,-2.2 2,-0.3 324,-0.1 -1,-0.3 0.253 99.6 80.4 -98.7 5.6 36.4 16.2 24.0 91 92 A L < - 0 0 0 -3,-1.7 2,-0.5 -4,-0.1 -33,-0.2 -0.878 64.5-149.9-118.0 149.5 34.4 13.5 25.6 92 93 A I E -d 58 0B 0 -35,-3.0 -33,-2.3 -2,-0.3 2,-0.5 -0.978 22.4-173.2-114.7 120.4 32.3 10.6 24.4 93 94 A I E -d 59 0B 0 -2,-0.5 40,-1.8 -35,-0.2 39,-1.5 -0.948 2.0-175.3-120.6 124.9 29.5 9.8 26.9 94 95 A S E +de 60 133B 0 -35,-1.8 -33,-1.8 -2,-0.5 2,-0.3 -0.876 6.5 176.6-114.0 149.8 27.2 6.9 26.5 95 96 A T E - e 0 134B 0 38,-1.9 40,-2.1 -2,-0.3 2,-0.3 -0.881 10.3-157.9-138.6-177.7 24.3 5.6 28.5 96 97 A K E - e 0 135B 0 -2,-0.3 -33,-2.0 38,-0.2 2,-0.3 -0.969 10.4-154.9-152.7 158.3 21.8 2.8 28.0 97 98 A A E + e 0 136B 0 38,-1.8 40,-2.2 -2,-0.3 41,-0.4 -0.974 52.5 89.1-141.9 138.3 18.4 1.4 28.8 98 99 A G + 0 0 0 1,-0.4 11,-2.2 -2,-0.3 2,-0.1 0.230 65.9 76.5 172.6 -34.3 17.2 -2.2 28.9 99 100 A Y S S- 0 0 85 9,-0.2 -1,-0.4 1,-0.2 2,-0.3 -0.273 99.2 -59.4 -87.5-176.2 17.6 -3.7 32.4 100 101 A D + 0 0 123 1,-0.2 8,-0.2 8,-0.1 -1,-0.2 -0.493 66.1 149.5 -68.3 123.7 15.5 -3.1 35.5 101 102 A M + 0 0 26 6,-2.5 -1,-0.2 1,-0.6 7,-0.1 0.700 64.8 4.5-120.8 -51.6 15.6 0.5 36.3 102 103 A W S S- 0 0 32 5,-0.9 -1,-0.6 2,-0.2 5,-0.1 -0.909 88.9 -85.7-137.8 162.4 12.4 1.5 38.0 103 104 A P S S+ 0 0 68 0, 0.0 3,-0.3 0, 0.0 5,-0.1 -0.250 79.7 38.5 -79.5 159.6 9.4 -0.6 38.9 104 105 A G S > S- 0 0 24 1,-0.2 3,-1.4 2,-0.1 -2,-0.2 -0.242 101.3 -57.2 99.7 174.0 6.5 -1.7 36.8 105 106 A P T 3 S+ 0 0 14 0, 0.0 1471,-0.2 0, 0.0 3,-0.2 0.500 130.2 53.5 -73.6 -6.0 6.1 -2.7 33.2 106 107 A Y T 3 S+ 0 0 2 -3,-0.3 -2,-0.1 1,-0.1 1538,-0.1 0.405 91.8 76.1-103.7 3.6 7.6 0.5 31.7 107 108 A G S < S+ 0 0 1 -3,-1.4 -6,-2.5 -5,-0.1 -5,-0.9 0.229 97.9 32.7-101.3 19.6 10.9 0.3 33.8 108 109 A S S S+ 0 0 28 -3,-0.2 3,-0.4 -8,-0.2 2,-0.3 -0.990 88.7 33.1-163.7 157.9 12.6 -2.4 31.8 109 110 A G S S- 0 0 4 -11,-2.2 28,-0.2 -2,-0.3 29,-0.1 -0.687 90.8 -55.7 98.0-150.1 13.0 -3.9 28.4 110 111 A G S S+ 0 0 1 -2,-0.3 41,-0.2 1464,-0.1 -1,-0.2 0.105 75.4 133.1-128.7 19.9 12.9 -2.4 24.9 111 112 A S > - 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0 0 12 -5,-2.4 -1,-0.3 -8,-0.1 -2,-0.2 -0.921 65.3-120.6-130.2 149.1 -19.3 -12.6 40.7 1805 280 F S > - 0 0 35 -2,-0.3 4,-2.4 30,-0.1 5,-0.2 -0.415 42.5-103.1 -72.5 163.8 -21.3 -9.4 40.6 1806 281 F M H > S+ 0 0 9 -23,-0.3 4,-2.7 1,-0.2 5,-0.2 0.944 123.9 53.4 -52.7 -49.6 -22.8 -8.5 37.4 1807 282 F A H > S+ 0 0 5 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.897 108.7 49.8 -52.5 -47.4 -20.1 -5.9 36.8 1808 283 F Q H > S+ 0 0 24 1,-0.2 4,-3.2 2,-0.2 5,-0.2 0.919 110.5 47.8 -64.0 -44.9 -17.4 -8.5 37.4 1809 284 F M H X S+ 0 0 0 -4,-2.4 4,-2.8 2,-0.2 -1,-0.2 0.939 110.4 53.5 -62.0 -42.2 -18.8 -11.0 35.0 1810 285 F A H X S+ 0 0 0 -4,-2.7 4,-1.3 -28,-0.3 -2,-0.2 0.899 114.0 41.7 -59.5 -39.7 -19.2 -8.2 32.4 1811 286 F L H X S+ 0 0 0 -4,-2.2 4,-2.0 2,-0.2 3,-0.2 0.926 113.7 52.3 -73.3 -43.8 -15.5 -7.3 32.7 1812 287 F S H X S+ 0 0 0 -4,-3.2 4,-0.6 1,-0.2 -2,-0.2 0.865 104.8 57.2 -60.6 -38.4 -14.4 -10.9 32.9 1813 288 F W H >< S+ 0 0 7 -4,-2.8 3,-0.9 -5,-0.2 -1,-0.2 0.914 106.9 46.5 -61.4 -42.3 -16.3 -11.7 29.7 1814 289 F L H >< S+ 0 0 0 -4,-1.3 3,-0.6 1,-0.2 6,-0.4 0.912 116.8 45.9 -65.4 -36.4 -14.4 -9.0 27.7 1815 290 F L H 3< S+ 0 0 2 -4,-2.0 -1,-0.2 1,-0.2 -2,-0.2 0.420 78.8 107.9 -85.9 -0.6 -11.2 -10.3 29.1 1816 291 F K T << S+ 0 0 54 -3,-0.9 2,-0.3 -4,-0.6 -1,-0.2 0.724 87.1 22.2 -50.3 -28.0 -12.0 -14.0 28.6 1817 292 F D S X S- 0 0 57 -3,-0.6 3,-1.2 -4,-0.2 27,-0.0 -0.916 89.1 -97.5-141.7 171.3 -9.4 -14.1 25.7 1818 293 F D T 3 S+ 0 0 133 -2,-0.3 -3,-0.1 1,-0.3 -2,-0.1 0.351 99.8 87.2 -75.2 9.6 -6.3 -12.3 24.4 1819 294 F R T 3 S+ 0 0 62 -5,-0.1 2,-0.5 1,-0.1 -1,-0.3 0.828 81.4 61.2 -80.7 -33.9 -8.3 -10.2 21.8 1820 295 F V < - 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0 0 109 -27,-0.0 2,-0.4 0, 0.0 -27,-0.1 -0.767 44.8-177.2 -99.5 139.0 -12.8 -18.5 32.3 1845 320 F F - 0 0 32 -2,-0.4 2,-0.1 -29,-0.1 -2,-0.0 -1.000 19.8-133.0-130.7 134.6 -16.1 -19.3 30.7 1846 321 F S > - 0 0 54 -2,-0.4 4,-2.3 1,-0.1 5,-0.2 -0.417 28.4-112.0 -76.5 155.6 -17.5 -22.7 29.5 1847 322 F T H > S+ 0 0 127 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.886 121.6 53.4 -52.0 -40.3 -19.0 -23.1 26.0 1848 323 F K H > S+ 0 0 149 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.949 107.5 49.0 -61.0 -51.5 -22.3 -23.7 27.9 1849 324 F E H > S+ 0 0 45 1,-0.2 4,-2.4 2,-0.2 -2,-0.2 0.901 111.6 49.4 -55.0 -44.8 -22.0 -20.4 29.9 1850 325 F L H X S+ 0 0 51 -4,-2.3 4,-2.6 2,-0.2 -1,-0.2 0.924 111.2 49.2 -63.8 -45.1 -21.2 -18.4 26.7 1851 326 F A H X S+ 0 0 57 -4,-2.4 4,-2.3 2,-0.2 -2,-0.2 0.899 111.7 48.9 -60.8 -43.2 -24.2 -19.9 24.9 1852 327 F Q H X S+ 0 0 69 -4,-2.6 4,-2.4 2,-0.2 -2,-0.2 0.880 110.4 51.4 -66.9 -38.5 -26.6 -19.2 27.8 1853 328 F I H X S+ 0 0 1 -4,-2.4 4,-1.7 -5,-0.2 -2,-0.2 0.965 111.8 46.5 -58.1 -53.1 -25.3 -15.6 28.0 1854 329 F D H < S+ 0 0 77 -4,-2.6 -2,-0.2 1,-0.2 -1,-0.2 0.895 110.6 53.9 -56.3 -41.7 -26.0 -15.1 24.3 1855 330 F Q H < S+ 0 0 162 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.937 106.5 50.0 -61.0 -51.3 -29.4 -16.7 24.6 1856 331 F H H < 0 0 51 -4,-2.4 -1,-0.2 -5,-0.1 -2,-0.2 0.848 360.0 360.0 -56.3 -34.0 -30.6 -14.3 27.4 1857 332 F I < 0 0 90 -4,-1.7 -3,-0.1 -5,-0.2 -106,-0.1 0.402 360.0 360.0 -76.3 360.0 -29.4 -11.4 25.2 1858 !* 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 1859 2 G V 0 0 89 0, 0.0 2,-0.5 0, 0.0 82,-0.1 0.000 360.0 360.0 360.0 137.9 17.2 52.4 12.1 1860 3 G W - 0 0 35 80,-0.2 2,-0.6 81,-0.1 -1549,-0.0 -0.980 360.0-161.8-127.4 123.4 17.0 56.0 13.4 1861 4 G L - 0 0 86 -2,-0.5 80,-0.0 -1551,-0.0 -1550,-0.0 -0.886 22.7-131.7-104.2 119.3 19.8 58.4 14.2 1862 5 G A - 0 0 1 -2,-0.6 46,-0.1 1,-0.1 49,-0.0 -0.339 39.9 -83.9 -65.4 152.8 18.8 61.3 16.4 1863 6 G N > - 0 0 61 1,-0.2 3,-1.7 2,-0.1 -1,-0.1 -0.375 33.7-145.6 -57.5 120.4 19.9 64.8 15.3 1864 7 G P T 3 S+ 0 0 99 0, 0.0 3,-0.4 0, 0.0 -1,-0.2 0.701 98.7 55.7 -60.9 -19.1 23.5 65.2 16.6 1865 8 G E T > S+ 0 0 144 1,-0.2 3,-2.4 2,-0.1 4,-0.4 0.289 72.6 114.8 -93.1 9.9 22.9 69.0 17.2 1866 9 G R T < S+ 0 0 19 -3,-1.7 4,-0.5 1,-0.3 3,-0.3 0.726 76.0 47.1 -55.7 -24.9 19.8 68.3 19.4 1867 10 G Y T 3 S+ 0 0 49 -3,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.340 92.4 84.9 -99.3 8.7 21.4 69.8 22.5 1868 11 G G S < S+ 0 0 62 -3,-2.4 -1,-0.2 1,-0.1 -2,-0.1 0.755 99.8 21.2 -83.5 -25.0 22.7 73.0 20.8 1869 12 G Q S S+ 0 0 179 -4,-0.4 -2,-0.1 -3,-0.3 -1,-0.1 0.753 93.7 98.8-117.6 -31.8 19.6 75.3 21.0 1870 13 G M - 0 0 12 -4,-0.5 2,-0.4 42,-0.2 43,-0.1 -0.239 65.7-134.5 -59.4 139.3 17.3 74.0 23.8 1871 14 G Q - 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q 01918Z 9 237,-2.7 239,-0.3 -2,-0.5 3,-0.3 -0.784 10.7-153.8 -97.3 147.5 3.0 66.2 27.4 1889 32 G L + 0 0 0 29,-2.1 4,-0.4 -2,-0.3 31,-0.1 0.001 57.4 121.8-112.2 24.6 1.2 63.2 25.9 1890 33 G W S S+ 0 0 83 28,-0.1 34,-0.8 33,-0.1 2,-0.3 0.901 80.7 20.0 -52.6 -46.2 -2.2 64.3 27.3 1891 34 G H S S+ 0 0 95 -3,-0.3 236,-0.4 32,-0.1 -1,-0.1 -0.868 114.8 30.3-126.6 158.4 -3.6 64.3 23.7 1892 35 G N S S+ 0 0 45 -2,-0.3 -1,-0.1 32,-0.3 -2,-0.1 0.416 94.2 86.0 80.0 2.9 -2.7 62.8 20.4 1893 36 G F + 0 0 0 31,-0.5 40,-0.3 -4,-0.4 41,-0.2 0.171 64.8 107.4-119.7 22.8 -1.1 59.7 21.7 1894 37 G G S > S- 0 0 0 30,-0.5 3,-1.4 39,-0.1 -1231,-0.2 -0.201 87.9 -97.3 -89.8 178.9 -4.1 57.5 22.1 1895 38 G H T 3 S+ 0 0 6 30,-0.8 -1231,-2.0 1,-0.3 -1232,-0.3 0.595 120.7 68.2 -73.0 -9.5 -5.3 54.5 20.1 1896 39 G V T 3 S+ 0 0 74 29,-1.1 2,-0.3 -1233,-0.2 -1,-0.3 0.597 94.5 69.7 -80.7 -11.5 -7.6 56.9 18.3 1897 40 G N S < S- 0 0 48 -3,-1.4 -1234,-0.5 28,-0.2 2,-0.2 -0.817 94.7-103.1-109.0 146.2 -4.5 58.6 16.7 1898 41 G A >> - 0 0 18 -2,-0.3 4,-1.6 -1238,-0.2 3,-0.6 -0.451 21.7-134.4 -70.6 137.6 -2.2 57.0 14.1 1899 42 G L H 3> S+ 0 0 13 -1238,-0.5 4,-2.9 -1240,-0.3 -1239,-0.2 0.815 101.7 61.9 -60.7 -32.3 1.1 55.6 15.4 1900 43 G E H 3> S+ 0 0 57 -1241,-2.1 4,-2.1 2,-0.2 -1,-0.2 0.874 103.9 48.4 -67.2 -34.1 3.0 57.2 12.5 1901 44 G S H <> S+ 0 0 40 -3,-0.6 4,-2.0 -1242,-0.3 -1,-0.2 0.933 112.2 49.5 -64.4 -46.9 2.0 60.6 13.5 1902 45 G Q H X S+ 0 0 2 -4,-1.6 4,-2.3 1,-0.2 -2,-0.2 0.916 108.6 53.7 -56.0 -45.9 2.9 59.9 17.1 1903 46 G R H X S+ 0 0 20 -4,-2.9 4,-2.4 1,-0.2 5,-0.2 0.930 107.6 49.7 -57.9 -47.6 6.3 58.5 15.9 1904 47 G A H X S+ 0 0 45 -4,-2.1 4,-2.4 1,-0.2 -1,-0.2 0.889 109.2 53.0 -58.6 -41.3 7.2 61.7 14.0 1905 48 G I H X S+ 0 0 1 -4,-2.0 4,-3.0 2,-0.2 -1,-0.2 0.953 110.3 45.2 -62.9 -47.9 6.3 63.9 17.0 1906 49 G L H X S+ 0 0 0 -4,-2.3 4,-2.5 1,-0.2 5,-0.2 0.940 114.2 49.6 -63.7 -43.6 8.5 62.0 19.5 1907 50 G R H X S+ 0 0 65 -4,-2.4 4,-2.3 -5,-0.2 -1,-0.2 0.928 114.9 43.8 -60.6 -43.4 11.4 61.9 17.0 1908 51 G K H X S+ 0 0 58 -4,-2.4 4,-1.5 -5,-0.2 -1,-0.2 0.911 109.7 55.5 -67.9 -43.3 11.1 65.6 16.3 1909 52 G A H ><>S+ 0 0 0 -4,-3.0 5,-2.3 1,-0.2 3,-0.8 0.958 113.1 42.2 -53.4 -51.0 10.7 66.5 20.0 1910 53 G F H ><5S+ 0 0 0 -4,-2.5 3,-1.6 1,-0.3 -1,-0.2 0.866 108.6 58.6 -67.8 -36.9 14.0 64.8 20.8 1911 54 G D H 3<5S+ 0 0 31 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.2 0.774 104.9 52.1 -61.0 -26.8 15.7 66.2 17.8 1912 55 G L T <<5S- 0 0 34 -4,-1.5 -1,-0.3 -3,-0.8 -2,-0.2 0.369 126.7-102.0 -89.4 0.8 14.8 69.7 19.2 1913 56 G G T < 5S+ 0 0 0 -3,-1.6 2,-1.0 1,-0.3 -3,-0.2 0.568 72.1 147.6 91.1 8.3 16.4 68.7 22.5 1914 57 G I < + 0 0 0 -5,-2.3 -1,-0.3 -6,-0.2 -2,-0.1 -0.734 14.4 169.7 -77.4 107.0 13.2 68.1 24.3 1915 58 G T + 0 0 0 -2,-1.0 35,-2.8 -30,-0.2 2,-0.5 0.373 48.3 82.3-100.4 -1.0 14.3 65.3 26.7 1916 59 G H E - r 01950Z 0 -31,-0.3 -29,-2.3 33,-0.2 2,-0.5 -0.948 49.6-178.3-120.4 126.8 11.2 65.2 28.9 1917 60 G F E -qr18871951Z 1 33,-2.4 35,-1.8 -2,-0.5 2,-0.5 -0.992 12.8-156.0-128.8 122.0 8.0 63.4 28.1 1918 61 G D E +qr18881952Z 0 -31,-2.5 -29,-2.1 -2,-0.5 2,-0.2 -0.884 19.5 166.4-111.0 119.2 5.2 63.6 30.6 1919 62 G L - 0 0 0 33,-1.7 2,-0.3 -2,-0.5 -29,-0.1 -0.614 18.4-157.3-119.0 179.8 2.6 60.9 30.7 1920 63 G A > - 0 0 0 -2,-0.2 3,-1.4 33,-0.2 8,-0.3 -0.963 34.3-110.1-154.1 152.9 -0.2 59.9 33.1 1921 64 G N T 3 S+ 0 0 0 33,-1.8 7,-1.0 -2,-0.3 10,-0.2 0.906 116.4 46.7 -50.7 -42.2 -2.0 56.6 33.5 1922 65 G N T 3 S+ 0 0 40 5,-0.2 -1,-0.2 32,-0.1 7,-0.1 0.441 80.6 124.1 -90.0 2.0 -5.2 57.9 32.0 1923 66 G Y < > + 0 0 4 -3,-1.4 7,-1.8 4,-0.1 5,-0.7 -0.365 53.2 41.6 -64.0 139.3 -3.8 59.6 29.0 1924 67 G G T 5S- 0 0 6 -34,-0.8 -31,-0.5 5,-0.2 -30,-0.5 -0.716 94.6 -79.4-179.0-124.7 -5.3 58.4 25.7 1925 68 G P T 5S+ 0 0 73 0, 0.0 -29,-1.1 0, 0.0 -30,-0.8 0.522 123.9 39.7 -91.5 161.4 -8.0 57.8 24.8 1926 69 G P T > 5S- 0 0 43 0, 0.0 3,-2.5 0, 0.0 4,-0.4 0.602 114.4 -95.7 -83.4 169.1 -8.6 55.1 25.8 1927 70 G P T 3 5S+ 0 0 73 0, 0.0 -5,-0.2 0, 0.0 -3,-0.2 -0.210 107.8 16.6 -54.7 137.4 -7.0 55.2 29.2 1928 71 G G T 3> S+ 0 0 2 -3,-2.5 4,-3.1 -6,-0.2 5,-0.3 0.843 72.7 56.3 -70.3 -33.0 -3.0 54.0 25.5 1930 73 G A H > S+ 0 0 0 -7,-1.8 4,-2.8 -4,-0.4 -1,-0.2 0.924 110.3 46.6 -59.7 -42.7 -0.6 56.9 25.5 1931 74 G E H > S+ 0 0 0 -8,-0.5 4,-2.5 -10,-0.2 -2,-0.2 0.949 113.2 48.4 -67.0 -45.9 1.6 54.9 27.8 1932 75 G E H X S+ 0 0 42 -4,-2.3 4,-2.1 2,-0.2 -2,-0.2 0.926 115.5 44.2 -55.8 -50.0 1.3 51.7 25.6 1933 76 G N H X S+ 0 0 11 -4,-3.1 4,-2.2 -40,-0.3 5,-0.2 0.923 113.1 50.7 -67.5 -38.1 2.1 53.7 22.4 1934 77 G F H X S+ 0 0 1 -4,-2.8 4,-2.9 -5,-0.3 -1,-0.2 0.907 108.9 52.9 -62.3 -41.4 4.9 55.6 24.0 1935 78 G G H X S+ 0 0 3 -4,-2.5 4,-2.0 1,-0.2 -1,-0.2 0.887 108.2 49.9 -63.7 -40.2 6.4 52.3 25.2 1936 79 G R H X S+ 0 0 20 -4,-2.1 4,-1.8 2,-0.2 -1,-0.2 0.920 113.4 44.6 -61.4 -45.8 6.3 50.9 21.7 1937 80 G L H X>S+ 0 0 0 -4,-2.2 4,-2.9 1,-0.2 5,-0.7 0.890 110.4 56.2 -71.8 -34.6 8.0 53.9 20.2 1938 81 G L H X5S+ 0 0 11 -4,-2.9 4,-1.5 -5,-0.2 7,-0.2 0.929 109.8 44.9 -56.3 -47.0 10.5 53.9 23.0 1939 82 G R H <5S+ 0 0 150 -4,-2.0 4,-0.3 -5,-0.2 -1,-0.2 0.833 120.3 39.8 -71.3 -31.5 11.5 50.3 22.3 1940 83 G E H <5S+ 0 0 71 -4,-1.8 -80,-0.2 -5,-0.1 -2,-0.2 0.925 133.3 15.8 -83.9 -46.5 11.7 50.9 18.4 1941 84 G D H <5S+ 0 0 19 -4,-2.9 -3,-0.2 -5,-0.2 -2,-0.2 0.604 127.8 43.8-105.9 -17.6 13.3 54.3 18.2 1942 85 G F >X< + 0 0 2 -4,-1.5 3,-1.8 -5,-0.7 4,-0.9 0.241 66.3 115.9-124.8 21.6 14.8 55.1 21.6 1943 86 G A G >4 S+ 0 0 81 1,-0.3 3,-0.6 -4,-0.3 -1,-0.1 0.905 89.3 40.4 -51.1 -47.5 16.5 51.9 22.7 1944 87 G A G 34 S+ 0 0 68 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.1 0.471 119.2 48.5 -82.5 -0.8 19.9 53.7 22.6 1945 88 G Y G X4 S+ 0 0 15 -3,-1.8 3,-2.2 -7,-0.2 -1,-0.2 0.399 70.1 105.1-123.2 3.0 18.5 56.9 24.1 1946 89 G R G X< S+ 0 0 34 -4,-0.9 3,-1.7 -3,-0.6 -1,-0.1 0.833 80.8 56.3 -57.8 -38.0 16.4 56.0 27.1 1947 90 G D G 3 S+ 0 0 33 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.1 0.510 102.3 58.0 -78.9 -0.3 19.0 57.3 29.6 1948 91 G E G < S+ 0 0 12 -3,-2.2 2,-0.3 -599,-0.1 -1,-0.3 0.271 99.1 81.4 -98.3 2.0 18.9 60.7 27.8 1949 92 G L < - 0 0 0 -3,-1.7 2,-0.5 -4,-0.1 -33,-0.2 -0.856 64.4-150.5-113.5 146.2 15.1 60.9 28.6 1950 93 G I E -r 1916 0Z 0 -35,-2.8 -33,-2.4 -2,-0.3 2,-0.5 -0.984 23.0-172.7-111.3 117.2 13.1 61.9 31.6 1951 94 G I E -r 1917 0Z 0 -2,-0.5 39,-1.9 -35,-0.2 40,-1.8 -0.947 2.5-174.9-116.6 128.0 9.9 60.0 31.6 1952 95 G S E +rs19181991Z 0 -35,-1.8 -33,-1.7 -2,-0.5 2,-0.3 -0.861 6.7 175.8-113.6 151.5 7.1 60.8 34.1 1953 96 G T E - s 01992Z 0 38,-1.8 40,-2.1 -2,-0.3 2,-0.3 -0.858 10.5-158.4-140.2-177.6 3.8 59.2 34.9 1954 97 G K E - s 01993Z 0 -2,-0.3 -33,-1.8 38,-0.2 2,-0.3 -0.978 12.1-154.0-154.4 156.3 1.1 59.8 37.5 1955 98 G A E + s 01994Z 0 38,-1.8 40,-2.3 -2,-0.3 41,-0.4 -0.983 54.0 89.6-140.3 133.0 -1.8 58.3 39.3 1956 99 G G + 0 0 0 1,-0.5 11,-2.4 -2,-0.3 3,-0.1 0.212 65.8 75.3 178.1 -32.6 -4.7 60.2 40.9 1957 100 G Y S S- 0 0 85 9,-0.2 -1,-0.5 1,-0.2 2,-0.3 -0.201 99.4 -59.8 -90.6-178.5 -7.6 60.7 38.5 1958 101 G D + 0 0 124 1,-0.2 8,-0.2 8,-0.1 -1,-0.2 -0.526 66.5 149.8 -67.0 122.5 -10.2 58.1 37.4 1959 102 G M + 0 0 26 6,-2.4 -1,-0.2 1,-0.6 7,-0.1 0.678 65.1 4.9-119.5 -56.2 -8.3 55.3 35.7 1960 103 G W S S- 0 0 26 5,-0.9 -1,-0.6 2,-0.2 5,-0.1 -0.934 89.9 -88.6-131.2 160.1 -10.1 52.1 36.2 1961 104 G P S S+ 0 0 70 0, 0.0 3,-0.3 0, 0.0 5,-0.1 -0.222 79.5 38.9 -73.9 161.0 -13.5 51.6 37.9 1962 105 G G S > S- 0 0 23 1,-0.2 3,-1.4 2,-0.1 -2,-0.2 -0.291 101.8 -55.9 96.8 178.5 -14.2 51.0 41.5 1963 106 G P T 3 S+ 0 0 12 0, 0.0 223,-0.3 0, 0.0 3,-0.2 0.514 130.1 52.6 -79.4 -4.5 -12.8 52.4 44.7 1964 107 G Y T 3 S+ 0 0 0 -3,-0.3 -2,-0.1 1,-0.1 11,-0.1 0.440 92.4 76.8-105.1 4.3 -9.2 51.4 44.1 1965 108 G G S < S+ 0 0 0 -3,-1.4 -6,-2.4 -5,-0.1 -5,-0.9 0.174 97.9 30.3 -98.2 17.5 -9.0 53.1 40.6 1966 109 G S S S+ 0 0 27 -3,-0.2 3,-0.4 -8,-0.2 2,-0.3 -0.988 88.2 35.5-165.9 155.2 -8.7 56.7 41.7 1967 110 G G S S- 0 0 4 -11,-2.4 28,-0.2 -2,-0.3 29,-0.1 -0.681 90.7 -55.6 100.1-148.5 -7.4 59.0 44.4 1968 111 G G S S+ 0 0 0 -2,-0.3 41,-0.2 216,-0.1 -1,-0.2 0.122 75.3 133.5-130.4 20.1 -4.3 58.8 46.6 1969 112 G S > - 0 0 3 -3,-0.4 4,-2.6 215,-0.2 5,-0.2 -0.300 64.3-120.3 -73.8 155.7 -4.3 55.4 48.4 1970 113 G R H > S+ 0 0 19 1,-0.2 4,-2.3 2,-0.2 5,-0.4 0.874 114.3 56.8 -59.1 -39.5 -1.3 53.2 48.6 1971 114 G K H > S+ 0 0 0 2,-0.2 4,-2.2 1,-0.2 5,-0.3 0.945 111.7 39.7 -54.3 -53.1 -3.3 50.5 46.8 1972 115 G Y H > S+ 0 0 0 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.936 116.9 47.9 -69.5 -48.3 -4.1 52.7 43.8 1973 116 G L H X S+ 0 0 0 -4,-2.6 4,-2.3 2,-0.2 -1,-0.2 0.914 116.9 40.2 -63.4 -45.6 -0.8 54.4 43.5 1974 117 G L H X S+ 0 0 11 -4,-2.3 4,-2.2 -5,-0.2 -2,-0.2 0.959 117.8 47.6 -75.5 -40.6 1.4 51.2 43.7 1975 118 G A H X S+ 0 0 0 -4,-2.2 4,-1.9 -5,-0.4 -2,-0.2 0.923 115.1 47.7 -63.6 -36.6 -1.0 49.1 41.6 1976 119 G S H X S+ 0 0 0 -4,-2.8 4,-3.0 -5,-0.3 -1,-0.2 0.880 107.6 53.0 -68.9 -44.6 -1.1 51.9 39.0 1977 120 G L H X S+ 0 0 1 -4,-2.3 4,-2.8 -5,-0.2 5,-0.3 0.949 110.4 50.3 -58.7 -40.8 2.7 52.5 38.9 1978 121 G D H X S+ 0 0 39 -4,-2.2 4,-2.2 2,-0.2 -2,-0.2 0.922 111.0 47.7 -61.6 -42.2 3.1 48.7 38.2 1979 122 G Q H X S+ 0 0 41 -4,-1.9 4,-2.8 2,-0.2 -2,-0.2 0.928 113.0 49.8 -63.1 -42.3 0.5 49.0 35.4 1980 123 G S H X S+ 0 0 0 -4,-3.0 4,-2.1 2,-0.2 -2,-0.2 0.919 110.1 49.1 -62.9 -45.2 2.2 52.0 34.0 1981 124 G L H X>S+ 0 0 14 -4,-2.8 5,-2.0 1,-0.2 4,-1.0 0.905 114.0 46.8 -63.7 -38.5 5.6 50.4 34.0 1982 125 G K H ><5S+ 0 0 182 -4,-2.2 3,-0.5 -5,-0.3 -1,-0.2 0.930 111.6 49.9 -66.8 -48.0 4.3 47.3 32.3 1983 126 G R H 3<5S+ 0 0 45 -4,-2.8 -2,-0.2 1,-0.2 -1,-0.2 0.859 117.7 40.6 -61.4 -33.8 2.4 49.3 29.7 1984 127 G M H 3<5S- 0 0 3 -4,-2.1 -1,-0.2 -5,-0.2 -2,-0.2 0.538 106.7-124.9 -93.0 -8.7 5.5 51.4 28.9 1985 128 G G T <<5 + 0 0 64 -4,-1.0 2,-0.3 -3,-0.5 -3,-0.2 0.839 62.6 139.2 65.0 39.0 7.9 48.5 29.1 1986 129 G L < - 0 0 25 -5,-2.0 -1,-0.2 -6,-0.2 3,-0.1 -0.815 57.9-148.1-113.9 154.1 10.1 50.2 31.7 1987 130 G E S S- 0 0 128 -2,-0.3 2,-0.3 1,-0.3 -1,-0.1 0.839 87.7 -8.1 -80.5 -36.8 11.9 49.2 34.8 1988 131 G Y - 0 0 15 -7,-0.1 2,-0.3 -3,-0.1 -1,-0.3 -0.993 62.4-124.6-154.0 156.8 11.3 52.6 36.3 1989 132 G V E - t 02019Z 0 29,-2.3 31,-1.7 -2,-0.3 32,-0.3 -0.767 20.6-134.1 -96.8 152.5 10.1 56.1 35.6 1990 133 G D E S+ 0 0 0 -39,-1.9 31,-1.9 -2,-0.3 2,-0.4 0.881 94.0 22.7 -69.2 -41.7 12.2 59.1 36.2 1991 134 G I E -st19522021Z 0 -40,-1.8 -38,-1.8 29,-0.2 2,-0.5 -0.989 64.7-170.6-132.1 124.8 9.4 60.9 37.9 1992 135 G F E -st19532022Z 0 29,-2.0 31,-2.4 -2,-0.4 2,-0.4 -0.964 17.1-163.1-111.9 130.3 6.3 59.5 39.5 1993 136 G Y E -st19542023Z 0 -40,-2.1 -38,-1.8 -2,-0.5 2,-0.6 -0.868 29.4-132.4-112.1 146.8 3.5 61.9 40.6 1994 137 G S E -st19552024Z 0 29,-1.8 31,-1.6 -2,-0.4 -38,-0.2 -0.864 33.2-148.8 -79.9 122.0 0.5 61.9 42.8 1995 138 G H - 0 0 12 -40,-2.3 2,-0.3 -2,-0.6 -39,-0.2 0.618 61.2 -15.4 -81.0 -19.3 -1.8 63.5 40.1 1996 139 G R S S- 0 0 72 -41,-0.4 -1,-0.1 -29,-0.1 30,-0.1 -0.964 81.3 -69.8-171.6 170.0 -4.0 65.4 42.5 1997 140 G V - 0 0 30 29,-0.5 2,-0.5 -2,-0.3 -30,-0.1 -0.425 30.8-162.4 -72.5 136.5 -5.2 65.9 46.1 1998 141 G D > - 0 0 28 3,-0.2 3,-1.3 -2,-0.1 8,-0.1 -0.957 0.3-167.1-117.1 108.3 -7.3 63.2 47.7 1999 142 G E T 3 S+ 0 0 156 -2,-0.5 -1,-0.1 1,-0.3 4,-0.1 0.726 85.9 56.1 -68.2 -19.3 -8.9 64.8 50.7 2000 143 G N T 3 S+ 0 0 96 2,-0.1 -1,-0.3 184,-0.1 -3,-0.0 0.445 95.5 71.5 -92.9 -5.1 -10.0 61.4 52.0 2001 144 G T S < S- 0 0 4 -3,-1.3 -3,-0.2 183,-0.1 182,-0.1 -0.963 88.4-116.9-110.2 129.2 -6.5 59.8 52.0 2002 145 G P >> - 0 0 31 0, 0.0 4,-1.6 0, 0.0 3,-1.5 -0.359 18.7-128.8 -65.2 142.7 -4.1 60.8 54.6 2003 146 G M H 3> S+ 0 0 19 1,-0.3 4,-3.2 2,-0.2 5,-0.3 0.770 106.6 67.6 -61.0 -27.8 -1.1 62.4 53.1 2004 147 G E H 3> S+ 0 0 99 2,-0.2 4,-1.7 1,-0.2 -1,-0.3 0.853 102.3 47.2 -56.2 -38.0 1.1 60.1 55.2 2005 148 G E H <> S+ 0 0 15 -3,-1.5 4,-2.1 2,-0.2 -2,-0.2 0.952 114.0 45.6 -73.9 -47.7 -0.3 57.2 53.1 2006 149 G T H X S+ 0 0 3 -4,-1.6 4,-2.5 2,-0.2 3,-0.3 0.959 114.6 47.4 -58.3 -51.0 0.3 59.0 49.8 2007 150 G A H X S+ 0 0 0 -4,-3.2 4,-2.2 1,-0.3 -1,-0.2 0.871 111.4 51.6 -61.1 -36.2 3.8 60.2 50.7 2008 151 G S H X S+ 0 0 17 -4,-1.7 4,-2.1 -5,-0.3 -1,-0.3 0.858 107.1 52.4 -72.4 -33.5 4.7 56.8 51.9 2009 152 G A H X S+ 0 0 0 -4,-2.1 4,-2.1 -3,-0.3 -2,-0.2 0.954 110.8 48.5 -63.9 -44.5 3.5 55.1 48.6 2010 153 G L H X S+ 0 0 0 -4,-2.5 4,-1.5 1,-0.2 -2,-0.2 0.906 109.9 52.3 -58.5 -42.0 5.7 57.6 46.7 2011 154 G A H X S+ 0 0 0 -4,-2.2 4,-2.7 1,-0.2 -1,-0.2 0.896 107.2 52.3 -64.2 -40.8 8.6 56.7 49.1 2012 155 G H H X S+ 0 0 20 -4,-2.1 4,-2.7 1,-0.2 6,-0.3 0.891 104.0 57.4 -62.0 -36.4 8.1 53.0 48.4 2013 156 G A H <>S+ 0 0 0 -4,-2.1 5,-1.9 1,-0.2 6,-1.2 0.891 111.3 42.1 -61.4 -41.2 8.3 53.7 44.7 2014 157 G V H ><5S+ 0 0 7 -4,-1.5 3,-1.5 4,-0.2 -2,-0.2 0.938 114.9 48.6 -71.7 -45.7 11.7 55.3 45.1 2015 158 G Q H 3<5S+ 0 0 88 -4,-2.7 -2,-0.2 1,-0.3 -1,-0.2 0.863 109.3 52.3 -64.6 -38.3 13.1 52.8 47.5 2016 159 G S T 3<5S- 0 0 53 -4,-2.7 -1,-0.3 -5,-0.2 -2,-0.2 0.445 116.4-113.0 -79.1 -0.1 12.0 49.8 45.4 2017 160 G G T < 5S+ 0 0 16 -3,-1.5 -3,-0.2 2,-0.3 -2,-0.1 0.666 86.7 116.4 78.0 15.6 13.7 51.3 42.3 2018 161 G K S - 0 0 41 -2,-0.4 4,-3.0 1,-0.1 5,-0.2 -0.132 33.2-103.1 -53.7 161.3 -2.2 73.8 47.5 2029 172 G P H > S+ 0 0 26 0, 0.0 4,-2.2 0, 0.0 5,-0.1 0.887 123.0 51.9 -57.4 -38.4 0.8 75.5 49.1 2030 173 G E H > S+ 0 0 169 2,-0.2 4,-2.0 1,-0.2 5,-0.1 0.919 113.6 41.3 -64.0 -48.4 -0.2 74.1 52.5 2031 174 G R H > S+ 0 0 77 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.894 113.2 54.4 -73.7 -33.3 -0.5 70.5 51.2 2032 175 G T H X S+ 0 0 0 -4,-3.0 4,-2.5 2,-0.2 -1,-0.2 0.923 108.0 50.5 -58.7 -44.8 2.7 70.9 49.2 2033 176 G Q H X S+ 0 0 63 -4,-2.2 4,-1.8 1,-0.2 -2,-0.2 0.921 111.4 47.2 -64.0 -42.1 4.5 72.0 52.3 2034 177 G K H X S+ 0 0 82 -4,-2.0 4,-2.9 1,-0.2 -1,-0.2 0.878 110.6 52.5 -66.5 -37.5 3.2 69.0 54.3 2035 178 G M H X S+ 0 0 0 -4,-2.3 4,-2.7 2,-0.2 5,-0.3 0.920 106.5 52.8 -69.9 -38.5 4.2 66.7 51.5 2036 179 G V H X S+ 0 0 5 -4,-2.5 4,-1.9 1,-0.2 -1,-0.2 0.913 112.7 46.5 -56.1 -41.7 7.7 68.1 51.4 2037 180 G E H X S+ 0 0 75 -4,-1.8 4,-1.2 2,-0.2 -2,-0.2 0.908 112.3 47.9 -69.7 -45.6 7.9 67.4 55.2 2038 181 G L H < S+ 0 0 6 -4,-2.9 3,-0.4 1,-0.2 4,-0.4 0.905 112.5 48.8 -65.3 -39.8 6.5 63.9 55.0 2039 182 G L H ><>S+ 0 0 0 -4,-2.7 5,-2.2 1,-0.2 3,-1.7 0.880 105.2 59.8 -69.5 -31.5 8.9 63.0 52.1 2040 183 G R H ><5S+ 0 0 123 -4,-1.9 3,-1.9 1,-0.3 -1,-0.2 0.827 92.2 66.6 -64.7 -27.8 11.7 64.4 54.1 2041 184 G E T 3<5S+ 0 0 104 -4,-1.2 -1,-0.3 -3,-0.4 -2,-0.2 0.734 106.4 42.6 -62.8 -21.4 11.0 61.9 56.9 2042 185 G W T < 5S- 0 0 48 -3,-1.7 -1,-0.3 -4,-0.4 -2,-0.2 0.259 122.1-108.6-103.2 10.2 12.1 59.3 54.3 2043 186 G K T < 5S+ 0 0 75 -3,-1.9 -3,-0.2 1,-0.2 -2,-0.1 0.828 78.7 132.3 60.8 36.7 15.1 61.3 53.2 2044 187 G I < - 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