==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GROWTH FACTOR 16-OCT-97 1AXM . COMPND 2 MOLECULE: ACIDIC FIBROBLAST GROWTH FACTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.D.DIGABRIELE,I.LAX,D.I.CHEN,C.M.SVAHN,M.JAYE,J.SCHLESSINGE . 770 6 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 38670.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 558 72.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 274 35.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 12 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 27 3.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 122 15.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 97 12.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 14 1.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 10 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 30 14 1 15 13 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 3 0 0 0 0 0 0 0 0 0 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A K 0 0 127 0, 0.0 36,-0.1 0, 0.0 38,-0.0 0.000 360.0 360.0 360.0 124.0 -12.4 -7.1 14.3 2 10 A K - 0 0 62 34,-0.1 36,-0.2 36,-0.0 34,-0.1 -0.908 360.0 -68.8-149.3 142.7 -16.3 -7.0 14.0 3 11 A P - 0 0 49 0, 0.0 126,-0.8 0, 0.0 34,-0.3 -0.042 63.5-177.4 -44.3 136.0 -18.2 -4.4 16.0 4 12 A K E -AB 36 128A 81 32,-3.7 32,-2.8 124,-0.2 2,-0.4 -0.476 24.4-116.8-120.0-168.7 -18.1 -5.1 19.8 5 13 A L E - B 0 127A 0 122,-1.6 122,-2.4 30,-0.2 2,-0.9 -0.982 15.1-142.0-135.3 137.1 -19.4 -3.7 23.1 6 14 A L E - B 0 126A 0 28,-0.4 9,-2.7 -2,-0.4 2,-0.6 -0.891 22.6-170.5-104.9 95.9 -17.3 -2.4 25.8 7 15 A Y E -CB 14 125A 68 118,-2.3 118,-2.9 -2,-0.9 2,-0.6 -0.843 12.2-144.4 -91.5 123.9 -19.0 -3.6 28.9 8 16 A C E >> -CB 13 124A 0 5,-3.1 4,-1.5 -2,-0.6 5,-0.9 -0.817 4.6-148.3 -93.2 118.5 -17.5 -2.1 32.1 9 17 A S T 45S+ 0 0 20 114,-1.8 2,-0.7 -2,-0.6 3,-0.2 0.891 83.6 78.7 -47.6 -52.2 -17.3 -4.3 35.2 10 18 A N T 45S- 0 0 16 110,-1.1 3,-0.3 113,-0.4 97,-0.1 -0.482 122.6 -9.1 -64.0 105.2 -17.8 -1.4 37.6 11 19 A G T 45S- 0 0 10 -2,-0.7 -1,-0.3 1,-0.2 -2,-0.2 0.123 101.3-107.7 93.5 -26.3 -21.5 -0.7 37.4 12 20 A G T <5 + 0 0 12 -4,-1.5 2,-0.3 1,-0.2 -1,-0.2 0.968 68.2 145.3 65.6 55.4 -22.1 -3.1 34.5 13 21 A H E < -C 8 0A 13 -5,-0.9 -5,-3.1 -3,-0.3 2,-0.4 -0.828 48.0-120.0-120.3 164.6 -22.7 -0.5 31.7 14 22 A F E -CD 7 26A 27 12,-4.1 12,-1.6 -2,-0.3 -7,-0.2 -0.862 35.6-106.5-108.7 134.4 -21.9 -0.5 28.1 15 23 A L E - D 0 25A 0 -9,-2.7 2,-0.4 -2,-0.4 -9,-0.3 -0.297 44.3-167.8 -58.7 139.6 -19.6 2.3 26.7 16 24 A R E - D 0 24A 49 8,-2.4 8,-2.2 -11,-0.1 2,-0.6 -0.993 25.8-160.7-141.2 140.9 -21.7 4.7 24.7 17 25 A I E - D 0 23A 0 16,-1.6 6,-0.2 -2,-0.4 38,-0.1 -0.877 23.9-149.4-121.0 91.0 -21.0 7.6 22.3 18 26 A L > - 0 0 30 4,-2.7 3,-1.6 -2,-0.6 4,-0.4 -0.316 28.0-109.0 -57.4 146.8 -24.1 9.8 22.1 19 27 A P T 3 S+ 0 0 75 0, 0.0 -1,-0.1 0, 0.0 14,-0.0 0.761 116.9 64.6 -49.9 -25.9 -24.7 11.6 18.8 20 28 A D T 3 S- 0 0 107 2,-0.1 -2,-0.1 1,-0.1 3,-0.1 0.028 123.9 -98.8 -89.6 24.2 -23.8 14.8 20.5 21 29 A G S < S+ 0 0 15 -3,-1.6 46,-1.9 1,-0.2 2,-0.5 0.539 79.7 140.3 72.4 7.7 -20.2 13.8 21.2 22 30 A T B -E 66 0A 67 -4,-0.4 -4,-2.7 44,-0.2 2,-0.4 -0.759 38.6-154.0 -89.5 122.7 -21.1 12.8 24.8 23 31 A V E +D 17 0A 3 42,-0.6 86,-0.4 -2,-0.5 2,-0.2 -0.782 35.0 120.1 -99.2 134.9 -19.4 9.7 26.2 24 32 A D E -D 16 0A 27 -8,-2.2 -8,-2.4 -2,-0.4 2,-0.3 -0.729 50.7 -94.0-160.5-154.1 -21.0 7.6 29.0 25 33 A G E -D 15 0A 8 82,-0.5 2,-0.3 -10,-0.2 -10,-0.2 -0.938 26.8-171.0-140.4 159.8 -22.3 4.2 29.8 26 34 A T E -D 14 0A 20 -12,-1.6 -12,-4.1 -2,-0.3 81,-0.1 -0.988 26.3-149.3-151.7 152.9 -25.7 2.5 29.7 27 35 A R S S+ 0 0 166 -2,-0.3 2,-0.9 -14,-0.3 3,-0.1 0.514 71.5 105.8 -98.0 -8.9 -27.2 -0.8 30.8 28 36 A D > - 0 0 79 1,-0.2 3,-1.4 -14,-0.1 6,-0.1 -0.622 50.0-171.2 -75.4 105.2 -29.7 -0.8 27.9 29 37 A R T 3 S+ 0 0 108 -2,-0.9 -1,-0.2 1,-0.3 5,-0.2 0.803 85.0 61.9 -66.4 -29.9 -28.3 -3.4 25.5 30 38 A S T 3 S+ 0 0 101 -3,-0.1 2,-0.5 2,-0.1 -1,-0.3 0.217 75.5 124.4 -82.1 14.1 -30.9 -2.3 23.0 31 39 A D X - 0 0 20 -3,-1.4 3,-1.0 1,-0.1 4,-0.1 -0.657 61.2-141.9 -78.1 125.8 -29.3 1.1 22.9 32 40 A Q T 3 S+ 0 0 122 -2,-0.5 -1,-0.1 1,-0.2 20,-0.1 0.108 91.5 59.1 -76.3 22.0 -28.3 2.0 19.3 33 41 A H T 3 S+ 0 0 38 19,-0.1 -16,-1.6 18,-0.1 -1,-0.2 0.087 80.5 79.1-137.2 23.2 -25.0 3.7 20.3 34 42 A I < + 0 0 0 -3,-1.0 2,-0.7 -18,-0.2 -28,-0.4 0.373 63.4 104.3-109.7 -0.2 -23.0 1.0 22.2 35 43 A Q - 0 0 29 -4,-0.1 16,-2.2 -30,-0.1 17,-0.5 -0.759 52.3-178.1 -83.7 116.8 -21.8 -0.9 19.1 36 44 A L E -AF 4 50A 0 -32,-2.8 -32,-3.7 -2,-0.7 2,-0.6 -0.949 22.8-147.7-124.7 138.6 -18.1 -0.0 18.7 37 45 A Q E - F 0 49A 48 12,-2.7 12,-2.4 -2,-0.4 2,-0.7 -0.898 15.8-148.2-103.7 120.3 -15.6 -1.0 16.0 38 46 A L E - F 0 48A 28 -2,-0.6 2,-0.6 -36,-0.2 10,-0.2 -0.814 10.7-164.1 -95.0 118.5 -12.1 -1.3 17.3 39 47 A S E - F 0 47A 54 8,-2.5 8,-1.6 -2,-0.7 2,-0.8 -0.859 10.5-144.9-104.2 114.1 -9.4 -0.4 14.7 40 48 A A + 0 0 78 -2,-0.6 6,-0.2 6,-0.2 3,-0.0 -0.663 18.3 178.4 -82.1 112.1 -5.8 -1.5 15.4 41 49 A E S S- 0 0 107 -2,-0.8 2,-0.2 4,-0.4 -1,-0.2 0.617 70.1 -17.9 -87.2 -10.5 -3.4 1.1 14.1 42 50 A S S S- 0 0 66 3,-0.8 0, 0.0 1,-0.0 0, 0.0 -0.711 95.0 -60.1-161.2-149.2 -0.3 -0.8 15.3 43 51 A V S S+ 0 0 153 -2,-0.2 -3,-0.0 1,-0.1 3,-0.0 0.817 128.0 13.2 -86.8 -31.7 0.6 -3.5 17.7 44 52 A G S S+ 0 0 21 34,-0.0 35,-2.6 2,-0.0 2,-0.2 0.518 110.7 82.8-122.5 -4.9 -0.6 -1.9 21.0 45 53 A E E - G 0 78A 32 33,-0.2 -3,-0.8 31,-0.0 -4,-0.4 -0.616 51.8-177.9-100.3 157.3 -2.7 1.0 19.9 46 54 A V E - G 0 77A 8 31,-1.9 31,-1.9 -6,-0.2 2,-0.4 -0.971 23.1-133.6-150.6 162.6 -6.4 1.0 18.8 47 55 A Y E -FG 39 76A 27 -8,-1.6 -8,-2.5 -2,-0.3 2,-0.7 -0.971 13.8-155.1-119.1 133.6 -9.1 3.3 17.6 48 56 A I E +F 38 0A 0 27,-0.5 9,-2.8 -2,-0.4 2,-0.5 -0.843 24.3 172.3-112.4 96.2 -12.6 3.0 19.2 49 57 A K E -FH 37 56A 74 -12,-2.4 -12,-2.7 -2,-0.7 7,-0.3 -0.917 32.3-119.4-115.3 131.2 -15.1 4.3 16.6 50 58 A S E > -F 36 0A 0 5,-2.9 4,-0.6 -2,-0.5 -14,-0.2 -0.242 11.5-153.3 -61.1 135.4 -18.9 4.1 16.9 51 59 A T T 4 S+ 0 0 65 -16,-2.2 -1,-0.1 2,-0.1 -15,-0.1 0.900 91.6 50.1 -79.0 -39.6 -20.6 2.1 14.2 52 60 A E T 4 S+ 0 0 102 -17,-0.5 -1,-0.1 1,-0.2 -19,-0.1 0.895 130.4 13.0 -68.3 -44.6 -23.9 4.1 14.4 53 61 A T T 4 S- 0 0 39 2,-0.1 -1,-0.2 -36,-0.1 -2,-0.1 0.541 93.1-127.1-110.6 -9.2 -22.5 7.7 14.1 54 62 A G < + 0 0 24 -4,-0.6 -3,-0.1 1,-0.2 2,-0.1 0.474 55.7 149.7 80.4 0.6 -19.0 7.1 13.0 55 63 A Q - 0 0 7 -38,-0.1 -5,-2.9 -6,-0.1 2,-0.5 -0.392 43.0-133.1 -72.2 142.3 -17.5 9.1 15.9 56 64 A Y E -HI 49 68A 44 12,-3.5 12,-3.1 -7,-0.3 2,-0.2 -0.814 21.3-120.7 -93.5 132.3 -14.1 8.3 17.3 57 65 A L E + I 0 67A 0 -9,-2.8 -9,-0.4 -2,-0.5 2,-0.3 -0.558 46.5 169.1 -70.1 131.2 -13.8 8.1 21.1 58 66 A A E - I 0 66A 0 8,-2.7 8,-2.4 -2,-0.2 2,-0.4 -0.939 30.2-136.0-142.5 168.0 -11.2 10.7 22.1 59 67 A X E - I 0 65A 0 15,-2.6 6,-0.2 -2,-0.3 35,-0.1 -0.948 17.1-146.8-133.6 120.3 -9.8 12.4 25.2 60 68 A D > - 0 0 35 4,-2.0 3,-1.8 -2,-0.4 52,-0.1 -0.015 39.6 -88.5 -71.8 178.9 -9.0 16.1 25.5 61 69 A T T 3 S+ 0 0 87 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.553 125.3 58.8 -63.2 -13.9 -6.2 17.8 27.5 62 70 A D T 3 S- 0 0 114 2,-0.2 -1,-0.3 50,-0.0 3,-0.1 0.249 118.1-108.2 -98.0 4.2 -8.6 17.9 30.5 63 71 A G S < S+ 0 0 0 -3,-1.8 49,-3.8 1,-0.3 2,-0.3 0.584 73.2 139.7 80.2 8.2 -9.1 14.2 30.7 64 72 A L - 0 0 77 47,-0.2 -4,-2.0 48,-0.1 2,-0.3 -0.704 48.5-130.8 -89.8 139.7 -12.7 14.4 29.4 65 73 A L E + I 0 59A 4 -2,-0.3 -42,-0.6 -6,-0.2 2,-0.3 -0.656 35.0 164.2 -86.5 144.7 -14.0 11.8 26.9 66 74 A Y E -EI 22 58A 57 -8,-2.4 -8,-2.7 -2,-0.3 2,-0.7 -0.968 41.3-102.5-155.2 165.1 -15.8 12.9 23.8 67 75 A G E - I 0 57A 12 -46,-1.9 2,-0.3 -2,-0.3 -10,-0.2 -0.855 38.1-168.2 -96.9 111.4 -17.0 11.9 20.4 68 76 A S E - I 0 56A 17 -12,-3.1 -12,-3.5 -2,-0.7 -47,-0.0 -0.775 23.2-148.7 -99.7 145.7 -14.8 13.2 17.6 69 77 A Q S S+ 0 0 147 -2,-0.3 -1,-0.1 -14,-0.2 -12,-0.1 0.410 83.8 58.1 -90.6 4.1 -15.6 13.2 13.9 70 78 A T S S- 0 0 83 -14,-0.2 2,-1.1 0, 0.0 -1,-0.1 -0.993 83.1-122.8-140.9 137.4 -12.0 12.8 13.1 71 79 A P + 0 0 57 0, 0.0 2,-0.2 0, 0.0 -13,-0.0 -0.662 52.6 156.2 -76.5 97.7 -9.2 10.3 13.9 72 80 A N > - 0 0 49 -2,-1.1 3,-1.7 -16,-0.0 4,-0.3 -0.527 62.6 -85.0-112.1-174.2 -6.6 12.7 15.5 73 81 A E G > S+ 0 0 125 1,-0.3 3,-1.1 -2,-0.2 20,-0.3 0.841 126.2 63.9 -63.2 -28.6 -3.8 12.1 18.0 74 82 A E G 3 S+ 0 0 40 1,-0.2 -15,-2.6 18,-0.1 -1,-0.3 0.390 96.9 58.7 -76.1 6.9 -6.4 12.5 20.8 75 83 A C G < S+ 0 0 0 -3,-1.7 -27,-0.5 -17,-0.2 2,-0.3 0.447 79.2 99.9-113.0 -6.9 -8.2 9.3 19.6 76 84 A L E < -G 47 0A 14 -3,-1.1 16,-1.7 -4,-0.3 17,-0.5 -0.692 49.6-176.4 -85.9 133.3 -5.5 6.7 19.9 77 85 A F E -GJ 46 91A 1 -31,-1.9 -31,-1.9 -2,-0.3 2,-0.5 -0.982 25.7-127.7-133.2 143.2 -5.4 4.4 22.9 78 86 A L E -GJ 45 90A 31 12,-2.6 12,-1.9 -2,-0.3 2,-0.6 -0.766 23.7-146.2 -86.9 126.2 -3.1 1.7 24.2 79 87 A E E + J 0 89A 60 -35,-2.6 2,-0.3 -2,-0.5 10,-0.2 -0.858 27.6 171.6 -96.8 122.4 -5.0 -1.5 25.0 80 88 A R E - 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