==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=16-NOV-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM 21-JUN-12 4AYI . COMPND 2 MOLECULE: COMPLEMENT FACTOR H; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.JOHNSON,L.TAN,S.VAN DER VEEN,J.CAESAR,E.GOICOECHEA DE JORG . 482 3 8 8 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 24633.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 309 64.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 191 39.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 10 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 45 9.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 50 10.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 8 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 5 4 10 1 5 2 1 1 2 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 5 2 2 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 324 A P 0 0 124 0, 0.0 2,-0.4 0, 0.0 24,-0.2 0.000 360.0 360.0 360.0 112.9 19.5 -15.9 44.8 2 325 A a B -A 24 0A 11 22,-1.9 22,-2.5 53,-0.1 49,-0.1 -0.713 360.0-146.6 -88.5 130.9 15.7 -16.6 45.0 3 326 A D - 0 0 113 -2,-0.4 21,-0.1 20,-0.2 -1,-0.1 -0.121 54.3 -47.9 -80.1-178.7 14.3 -20.0 43.8 4 327 A Y S S- 0 0 63 1,-0.1 2,-0.4 15,-0.1 -1,-0.2 -0.282 71.0-112.6 -53.1 129.9 10.8 -20.3 42.2 5 328 A P - 0 0 5 0, 0.0 2,-1.1 0, 0.0 7,-0.2 -0.561 14.9-147.8 -75.7 128.5 8.3 -18.4 44.4 6 329 A D - 0 0 126 -2,-0.4 2,-0.9 5,-0.1 5,-0.1 -0.834 21.8-171.0 -88.8 93.8 5.7 -20.4 46.3 7 330 A I > - 0 0 14 -2,-1.1 3,-1.7 3,-0.2 2,-0.4 -0.886 14.9-143.4 -94.6 101.4 3.0 -17.7 46.1 8 331 A K T 3 S+ 0 0 138 -2,-0.9 54,-0.4 1,-0.3 3,-0.1 -0.588 85.6 6.3 -71.1 124.0 0.3 -19.1 48.4 9 332 A H T 3 S+ 0 0 56 -2,-0.4 26,-3.5 1,-0.3 -1,-0.3 0.622 134.3 44.7 74.3 21.8 -3.1 -18.2 46.9 10 333 A G E < -B 34 0B 15 -3,-1.7 -1,-0.3 24,-0.3 2,-0.3 -0.716 62.1-164.3-156.8-152.9 -1.4 -16.8 43.7 11 334 A G E -B 33 0B 12 22,-1.5 22,-2.4 -2,-0.2 2,-0.2 -0.914 32.0 -66.2 166.8 173.3 1.2 -17.4 41.1 12 335 A L E > -B 32 0B 5 -2,-0.3 3,-0.6 20,-0.2 20,-0.2 -0.534 36.5-128.3 -84.5 144.9 3.4 -16.0 38.4 13 336 A Y T 3 S+ 0 0 9 18,-1.8 5,-0.2 1,-0.2 229,-0.1 -0.501 99.7 22.9 -78.1 159.6 2.2 -14.7 35.0 14 337 A H T 3> S+ 0 0 8 227,-0.4 4,-1.9 -2,-0.2 3,-0.3 0.858 79.9 165.9 47.6 41.2 4.1 -16.4 32.1 15 338 A E H <> + 0 0 70 -3,-0.6 4,-2.6 1,-0.2 -2,-0.1 0.859 67.9 54.0 -52.4 -46.6 4.9 -19.3 34.4 16 339 A N H 4 S+ 0 0 48 1,-0.2 294,-0.3 2,-0.2 -1,-0.2 0.870 112.4 43.5 -59.1 -43.1 6.1 -21.6 31.6 17 340 A M H 4 S+ 0 0 0 -3,-0.3 -1,-0.2 1,-0.2 -2,-0.2 0.870 119.9 40.8 -69.1 -45.0 8.6 -19.1 30.2 18 341 A R H >< S+ 0 0 6 -4,-1.9 3,-1.9 1,-0.2 -2,-0.2 0.777 97.1 76.5 -76.5 -37.5 10.0 -18.0 33.7 19 342 A R G >< S+ 0 0 103 -4,-2.6 3,-1.4 1,-0.3 -1,-0.2 0.857 89.8 55.0 -46.3 -50.5 10.2 -21.5 35.4 20 343 A P G 3 S+ 0 0 33 0, 0.0 -1,-0.3 0, 0.0 -2,-0.1 0.530 101.8 61.9 -66.5 -4.8 13.4 -22.8 33.6 21 344 A Y G < S+ 0 0 30 -3,-1.9 -2,-0.2 -4,-0.1 -3,-0.1 0.293 79.6 150.9-107.2 9.0 15.4 -19.7 34.7 22 345 A F < + 0 0 37 -3,-1.4 -19,-0.2 -4,-0.2 2,-0.1 -0.617 40.9 58.9 -84.9 143.2 15.2 -20.1 38.5 23 346 A P S S- 0 0 79 0, 0.0 2,-0.3 0, 0.0 -20,-0.2 0.473 75.5-164.6 -76.7 153.7 17.2 -19.2 40.7 24 347 A V B -A 2 0A 11 -22,-2.5 -22,-1.9 -2,-0.1 3,-0.1 -0.815 19.5-109.2-107.0 146.8 17.1 -15.5 39.9 25 348 A A > - 0 0 63 -2,-0.3 3,-1.7 -24,-0.2 26,-0.2 -0.221 46.5 -80.7 -70.4 162.4 19.6 -12.9 41.2 26 349 A V T 3 S+ 0 0 73 1,-0.2 26,-0.2 24,-0.1 -1,-0.1 -0.469 119.0 39.2 -65.7 130.5 18.8 -10.2 43.9 27 350 A G T 3 S+ 0 0 35 24,-3.3 -1,-0.2 1,-0.4 25,-0.1 0.092 85.5 125.4 112.2 -16.6 17.0 -7.3 42.2 28 351 A K < - 0 0 19 -3,-1.7 23,-3.3 23,-0.2 -1,-0.4 -0.424 37.0-176.3 -74.5 146.2 14.9 -9.5 39.9 29 352 A Y E - C 0 50B 3 21,-0.2 2,-0.3 -2,-0.1 21,-0.2 -0.991 10.2-163.2-146.9 151.0 11.1 -9.1 39.9 30 353 A Y E - C 0 49B 4 19,-2.1 19,-3.0 -2,-0.3 2,-0.2 -0.990 26.8-110.6-139.9 146.7 8.1 -10.7 38.3 31 354 A S E - C 0 48B 0 -2,-0.3 -18,-1.8 17,-0.2 2,-0.3 -0.485 42.2-179.6 -71.6 137.1 4.4 -9.9 37.7 32 355 A Y E -BC 12 47B 0 15,-3.0 15,-2.1 -20,-0.2 2,-0.2 -0.963 15.7-146.7-139.6 156.4 2.1 -12.1 39.8 33 356 A Y E -BC 11 46B 69 -22,-2.4 -22,-1.5 -2,-0.3 2,-0.4 -0.746 13.1-129.1-116.7 166.9 -1.7 -12.5 40.3 34 357 A b E -B 10 0B 1 11,-2.3 114,-0.6 -2,-0.2 -24,-0.3 -0.932 25.0-122.0-118.3 142.5 -3.9 -13.5 43.3 35 358 A D > - 0 0 74 -26,-3.5 3,-1.8 -2,-0.4 -1,-0.0 -0.127 51.2 -54.1 -70.4 177.1 -6.6 -16.2 43.2 36 359 A E T 3 S+ 0 0 80 1,-0.3 -1,-0.2 28,-0.0 113,-0.1 -0.161 127.9 18.4 -52.1 137.9 -10.3 -15.9 43.9 37 360 A H T 3 S+ 0 0 76 1,-0.2 28,-2.4 111,-0.2 2,-0.3 0.454 113.6 96.2 71.2 6.4 -11.1 -14.3 47.4 38 361 A F E < +E 64 0C 10 -3,-1.8 2,-0.3 26,-0.3 26,-0.2 -0.883 47.7 179.7-127.2 158.0 -7.5 -12.9 47.5 39 362 A E E -E 63 0C 8 24,-2.5 24,-3.4 -2,-0.3 6,-0.2 -0.969 32.3 -99.8-149.3 160.7 -5.7 -9.7 46.7 40 363 A T > - 0 0 1 4,-3.1 3,-2.4 -2,-0.3 22,-0.2 -0.383 44.5-103.7 -74.6 160.2 -2.3 -8.1 46.7 41 364 A P T 3 S+ 0 0 77 0, 0.0 -1,-0.1 0, 0.0 21,-0.1 0.772 123.8 61.3 -57.1 -23.5 -1.3 -5.7 49.6 42 365 A S T 3 S- 0 0 64 2,-0.1 3,-0.1 4,-0.1 5,-0.0 0.465 121.5-109.7 -79.0 -5.4 -1.9 -2.8 47.2 43 366 A G S < S+ 0 0 21 -3,-2.4 2,-0.2 1,-0.3 -1,-0.0 0.650 81.9 113.4 84.0 20.5 -5.6 -3.9 46.9 44 367 A S S S- 0 0 11 2,-0.1 -4,-3.1 -4,-0.1 -1,-0.3 -0.634 76.5-118.4-113.6 171.3 -5.3 -5.2 43.3 45 368 A Y S S+ 0 0 2 -6,-0.2 -11,-2.3 -2,-0.2 2,-0.3 0.630 97.7 31.0 -83.7 -15.2 -5.5 -8.7 41.7 46 369 A W E +C 33 0B 15 -13,-0.3 2,-0.2 -6,-0.1 -13,-0.2 -0.947 60.8 142.4-140.7 160.2 -1.9 -8.4 40.4 47 370 A D E -C 32 0B 51 -15,-2.1 -15,-3.0 -2,-0.3 2,-0.4 -0.875 48.6 -74.5-168.1-166.1 1.5 -6.8 41.3 48 371 A H E -C 31 0B 16 -17,-0.3 2,-0.4 -2,-0.2 -17,-0.2 -0.915 29.6-150.2-112.5 138.5 5.3 -7.5 41.2 49 372 A I E -C 30 0B 2 -19,-3.0 -19,-2.1 -2,-0.4 2,-0.4 -0.920 20.2-149.0-107.2 130.8 7.1 -9.9 43.5 50 373 A H E -CD 29 57B 56 7,-3.8 7,-2.5 -2,-0.4 2,-0.9 -0.868 14.6-133.5-110.4 139.7 10.8 -8.9 44.2 51 374 A a E + D 0 56B 2 -23,-3.3 -24,-3.3 -2,-0.4 5,-0.2 -0.809 40.4 174.4 -89.9 104.8 13.9 -11.0 44.9 52 375 A T E > - D 0 55B 54 3,-2.5 3,-1.5 -2,-0.9 -24,-0.0 -0.503 50.0-100.6-102.4 172.0 15.5 -9.1 47.8 53 376 A Q T 3 S+ 0 0 178 1,-0.3 3,-0.1 -2,-0.2 -27,-0.0 0.743 128.1 51.6 -66.1 -23.5 18.5 -10.0 50.0 54 377 A D T 3 S- 0 0 164 1,-0.4 -1,-0.3 0, 0.0 2,-0.2 0.199 124.1-103.8 -94.8 9.3 15.9 -11.2 52.6 55 378 A G E < S+D 52 0B 28 -3,-1.5 -3,-2.5 2,-0.0 -1,-0.4 -0.635 75.5 2.9 100.8-158.9 14.1 -13.4 50.0 56 379 A W E S-D 51 0B 52 -2,-0.2 -5,-0.2 -5,-0.2 -27,-0.1 -0.430 74.6-128.2 -68.1 133.0 10.8 -12.8 48.1 57 380 A S E S+D 50 0B 55 -7,-2.5 -7,-3.8 -2,-0.2 2,-0.2 -0.999 91.2 45.4-130.4 129.3 9.0 -9.4 48.7 58 381 A P S S- 0 0 34 0, 0.0 4,-0.1 0, 0.0 -1,-0.0 0.457 77.6-157.7 -61.9 146.7 6.1 -9.0 49.5 59 382 A A S S+ 0 0 93 1,-0.3 -3,-0.1 -2,-0.2 -2,-0.1 0.838 92.3 35.8 -69.6 -35.7 6.5 -11.8 52.1 60 383 A V S S+ 0 0 88 1,-0.1 -1,-0.3 -53,-0.1 3,-0.1 -0.879 76.1 174.2-116.8 86.6 2.7 -12.3 52.1 61 384 A P + 0 0 13 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 0.831 64.8 45.3 -67.3 -32.1 1.9 -11.6 48.4 62 385 A b - 0 0 4 -54,-0.4 2,-0.3 -22,-0.2 -22,-0.2 -0.969 66.8-173.3-124.1 120.2 -1.8 -12.6 48.6 63 386 A L E -E 39 0C 40 -24,-3.4 -24,-2.5 -2,-0.5 2,-0.0 -0.850 30.5-105.9-109.8 142.4 -4.2 -11.5 51.3 64 387 A R E -E 38 0C 38 -2,-0.3 21,-2.9 -26,-0.2 2,-0.4 -0.336 27.0-158.3 -66.8 144.7 -7.8 -12.6 51.9 65 388 A K E -F 84 0D 5 -28,-2.4 2,-0.5 19,-0.2 19,-0.2 -0.998 5.8-163.2-125.2 125.6 -10.6 -10.3 51.0 66 389 A c E -F 83 0D 3 17,-3.6 17,-2.7 -2,-0.4 2,-0.4 -0.970 6.7-150.8-114.3 124.9 -14.0 -10.8 52.7 67 390 A Y E -F 82 0D 33 -2,-0.5 15,-0.2 15,-0.2 46,-0.1 -0.818 26.8-116.2 -93.8 132.6 -17.1 -9.3 51.3 68 391 A F - 0 0 5 13,-2.8 12,-2.1 -2,-0.4 13,-0.3 -0.583 36.9-135.4 -71.0 119.7 -19.8 -8.6 53.9 69 392 A P - 0 0 25 0, 0.0 2,-0.1 0, 0.0 9,-0.1 -0.344 22.1 -91.3 -78.1 162.6 -22.8 -10.7 53.0 70 393 A Y - 0 0 135 124,-0.1 2,-0.6 9,-0.1 5,-0.1 -0.456 42.9-141.4 -65.7 134.9 -26.5 -9.8 52.9 71 394 A L > - 0 0 4 3,-0.2 3,-1.0 -2,-0.1 2,-0.4 -0.932 7.1-154.7-109.0 117.8 -28.1 -10.5 56.3 72 395 A E T 3 S+ 0 0 144 -2,-0.6 47,-0.5 1,-0.2 3,-0.1 -0.748 93.7 14.4 -82.1 132.9 -31.6 -11.9 56.5 73 396 A N T 3 S+ 0 0 37 -2,-0.4 21,-2.5 1,-0.2 2,-0.3 0.749 120.4 87.2 67.4 28.3 -32.8 -10.9 60.0 74 397 A G B < S-G 93 0E 1 -3,-1.0 2,-0.4 19,-0.3 19,-0.3 -0.938 87.9 -88.7-147.2 165.0 -30.0 -8.3 60.3 75 398 A Y - 0 0 116 17,-3.2 3,-0.4 -2,-0.3 17,-0.3 -0.681 29.7-154.0 -83.2 130.2 -29.1 -4.7 59.4 76 399 A N > + 0 0 53 -2,-0.4 3,-1.3 1,-0.2 -1,-0.1 -0.047 55.4 120.6 -98.2 32.4 -27.6 -4.4 55.9 77 400 A Q T 3 S+ 0 0 171 1,-0.3 -1,-0.2 15,-0.1 -2,-0.0 0.703 84.1 42.4 -66.2 -21.9 -25.5 -1.2 56.3 78 401 A N T > S+ 0 0 37 -3,-0.4 3,-0.8 -9,-0.1 -10,-0.3 0.209 80.7 135.9-108.9 10.8 -22.3 -3.1 55.4 79 402 A H T < S+ 0 0 81 -3,-1.3 3,-0.1 1,-0.3 -9,-0.1 -0.425 77.9 12.6 -64.4 126.5 -23.7 -5.3 52.5 80 403 A G T 3 S+ 0 0 23 -12,-2.1 149,-1.1 1,-0.3 2,-0.4 0.943 94.0 140.0 69.5 42.7 -21.3 -5.3 49.6 81 404 A R < - 0 0 89 -3,-0.8 -13,-2.8 -13,-0.3 2,-0.4 -0.988 47.2-134.1-116.6 132.2 -18.5 -3.9 51.7 82 405 A K E -F 67 0D 24 144,-1.8 2,-0.4 -2,-0.4 -15,-0.2 -0.759 20.7-173.8 -91.0 131.0 -14.9 -5.3 51.2 83 406 A F E -F 66 0D 10 -17,-2.7 -17,-3.6 -2,-0.4 2,-0.2 -0.974 16.8-136.1-124.2 136.6 -12.8 -6.1 54.2 84 407 A V E > -F 65 0D 51 -2,-0.4 3,-2.2 -19,-0.2 24,-0.3 -0.623 44.2 -71.3 -91.9 151.9 -9.1 -7.2 54.0 85 408 A Q T 3 S+ 0 0 64 -21,-2.9 24,-0.2 1,-0.3 -1,-0.1 -0.101 121.3 25.1 -42.7 127.8 -7.6 -10.2 56.0 86 409 A G T 3 S+ 0 0 58 22,-3.8 -1,-0.3 1,-0.4 2,-0.1 -0.057 93.3 118.4 103.2 -27.3 -7.2 -9.3 59.7 87 410 A K < - 0 0 144 -3,-2.2 21,-2.9 20,-0.1 -1,-0.4 -0.429 47.0-156.8 -74.7 144.1 -10.0 -6.7 59.7 88 411 A S E -H 107 0F 66 19,-0.2 2,-0.3 -2,-0.1 19,-0.2 -0.812 6.4-165.8-119.1 158.6 -13.1 -7.2 61.9 89 412 A I E -H 106 0F 29 17,-2.2 17,-2.4 -2,-0.3 2,-0.1 -0.988 24.6-114.3-148.6 138.2 -16.7 -5.8 61.8 90 413 A D E -H 105 0F 115 -2,-0.3 2,-0.6 15,-0.2 15,-0.2 -0.403 26.6-136.7 -67.0 143.6 -19.6 -5.6 64.2 91 414 A V - 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