==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=25-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 30-DEC-98 1B4V . COMPND 2 MOLECULE: PROTEIN (CHOLESTEROL OXIDASE); . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES SP.; . AUTHOR A.VRIELINK,Q.K.YUE . 498 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18315.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 348 69.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 26 5.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 79 15.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 51 10.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 9.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 101 20.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 14 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 2 2 1 1 0 0 2 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 9 2 1 1 2 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 2 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A G 0 0 86 0, 0.0 272,-3.1 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 58.8 26.0 1.0 48.3 2 10 A Y E +a 273 0A 130 270,-0.2 272,-0.2 252,-0.0 3,-0.1 -0.891 360.0 171.6-112.1 137.5 29.1 -0.8 47.0 3 11 A V E -a 274 0A 27 270,-2.0 272,-0.6 -2,-0.4 273,-0.2 -0.993 36.7-126.9-139.2 133.6 29.3 -3.4 44.1 4 12 A P E S+ 0 0 40 0, 0.0 272,-2.5 0, 0.0 271,-2.1 0.916 94.5 17.5 -46.6 -53.7 32.5 -4.7 42.6 5 13 A A E -ab 276 28A 0 22,-2.1 24,-2.4 270,-0.2 2,-0.4 -0.959 66.0-167.5-126.7 140.5 31.5 -3.9 39.0 6 14 A V E -ab 277 29A 0 270,-2.2 272,-2.9 -2,-0.4 2,-0.5 -0.990 3.3-163.9-125.7 133.5 28.7 -1.6 37.7 7 15 A V E -ab 278 30A 0 22,-2.6 24,-2.4 -2,-0.4 2,-0.6 -0.985 13.5-144.6-117.1 123.6 27.5 -1.6 34.1 8 16 A I E +ab 279 31A 9 270,-2.8 272,-2.1 -2,-0.5 24,-0.2 -0.821 67.8 3.7 -90.8 121.9 25.5 1.5 33.0 9 17 A G - 0 0 8 22,-3.3 22,-0.2 -2,-0.6 272,-0.2 -0.117 68.0-118.9 92.4 166.1 22.8 0.5 30.5 10 18 A T + 0 0 0 93,-0.3 95,-0.3 270,-0.1 -1,-0.1 -0.030 67.4 115.0-136.7 32.0 21.7 -2.9 29.2 11 19 A G S > S- 0 0 12 269,-0.8 4,-2.9 93,-0.1 5,-0.2 0.075 85.8 -64.6 -83.0-158.2 22.3 -2.6 25.4 12 20 A Y H > S+ 0 0 21 2,-0.2 4,-2.1 1,-0.2 5,-0.2 0.931 133.2 43.0 -59.4 -54.0 24.8 -4.6 23.3 13 21 A G H > S+ 0 0 1 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.919 118.7 46.4 -59.9 -43.9 28.0 -3.4 24.8 14 22 A A H > S+ 0 0 0 266,-0.4 4,-2.8 2,-0.2 -2,-0.2 0.902 110.8 51.2 -64.6 -45.5 26.6 -3.6 28.4 15 23 A A H X S+ 0 0 0 -4,-2.9 4,-1.9 2,-0.2 -1,-0.2 0.897 111.1 47.1 -61.1 -45.3 25.1 -7.1 27.9 16 24 A V H X S+ 0 0 0 -4,-2.1 4,-2.1 -5,-0.2 5,-0.2 0.948 114.4 48.3 -61.8 -47.5 28.4 -8.6 26.6 17 25 A S H X S+ 0 0 1 -4,-1.9 4,-2.4 -5,-0.2 -2,-0.2 0.924 110.9 48.9 -60.4 -47.9 30.4 -7.0 29.4 18 26 A A H X S+ 0 0 0 -4,-2.8 4,-2.4 2,-0.2 -1,-0.2 0.861 110.0 52.3 -62.0 -39.3 28.0 -8.2 32.2 19 27 A L H X S+ 0 0 2 -4,-1.9 4,-2.3 -5,-0.2 -1,-0.2 0.964 113.2 42.1 -61.5 -53.7 28.0 -11.8 31.0 20 28 A R H X S+ 0 0 40 -4,-2.1 4,-1.4 1,-0.2 -2,-0.2 0.870 114.1 52.4 -63.8 -37.2 31.7 -12.1 30.8 21 29 A L H <>S+ 0 0 0 -4,-2.4 5,-2.6 -5,-0.2 3,-0.3 0.930 110.7 48.0 -63.7 -44.5 32.2 -10.3 34.1 22 30 A G H ><5S+ 0 0 4 -4,-2.4 3,-1.5 1,-0.2 -2,-0.2 0.895 110.0 51.4 -62.9 -40.9 29.7 -12.7 35.8 23 31 A E H 3<5S+ 0 0 113 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.754 105.9 56.3 -67.1 -26.5 31.4 -15.7 34.3 24 32 A A T 3<5S- 0 0 54 -4,-1.4 -1,-0.3 -3,-0.3 -2,-0.2 0.370 123.5-106.6 -84.8 2.1 34.7 -14.4 35.7 25 33 A G T < 5S+ 0 0 43 -3,-1.5 2,-0.7 1,-0.2 -3,-0.2 0.606 71.6 143.8 83.7 13.6 33.1 -14.3 39.2 26 34 A V < - 0 0 15 -5,-2.6 2,-0.3 -6,-0.2 -1,-0.2 -0.781 53.0-127.4 -91.9 115.5 32.8 -10.6 39.4 27 35 A Q - 0 0 66 -2,-0.7 -22,-2.1 207,-0.1 2,-0.4 -0.461 38.4-169.9 -60.9 119.2 29.6 -9.4 41.3 28 36 A T E -bc 5 234A 0 205,-3.3 207,-2.2 -2,-0.3 2,-0.5 -0.938 21.0-160.7-124.4 137.3 28.0 -7.0 38.8 29 37 A L E -bc 6 235A 5 -24,-2.4 -22,-2.6 -2,-0.4 2,-0.4 -0.973 9.6-157.9-116.7 123.3 25.2 -4.5 39.0 30 38 A M E -bc 7 236A 0 205,-2.9 207,-2.7 -2,-0.5 2,-0.6 -0.857 4.6-156.1-100.7 132.6 23.5 -3.3 35.8 31 39 A L E -bc 8 237A 2 -24,-2.4 -22,-3.3 -2,-0.4 2,-0.5 -0.954 13.0-177.8-113.1 115.9 21.6 0.0 36.0 32 40 A E E - c 0 238A 11 205,-2.7 208,-2.6 -2,-0.6 207,-0.5 -0.963 21.2-158.0-117.4 128.0 19.0 0.6 33.3 33 41 A M S S+ 0 0 33 -2,-0.5 208,-0.2 206,-0.3 227,-0.1 0.772 78.2 61.4 -73.2 -27.2 16.9 3.8 33.0 34 42 A G S S- 0 0 0 206,-0.1 205,-2.2 1,-0.1 206,-0.3 -0.128 93.1 -82.9 -87.1-170.4 14.1 2.0 31.1 35 43 A Q - 0 0 28 67,-0.5 69,-2.5 50,-0.3 2,-0.8 -0.501 28.9-111.0 -97.0 163.6 11.8 -0.9 32.2 36 44 A L - 0 0 78 67,-0.2 2,-1.7 -2,-0.2 3,-0.3 -0.852 39.1-138.4 -87.0 109.1 12.1 -4.6 32.2 37 45 A W + 0 0 15 -2,-0.8 9,-0.1 67,-0.3 10,-0.1 -0.534 68.5 104.6 -82.1 85.0 9.6 -5.4 29.5 38 46 A N + 0 0 81 -2,-1.7 -1,-0.2 8,-0.1 8,-0.1 0.266 46.4 101.4-143.0 11.1 7.7 -8.4 30.8 39 47 A Q S S- 0 0 135 -3,-0.3 6,-0.1 7,-0.1 2,-0.0 -0.896 70.7-122.9-106.2 121.6 4.2 -7.1 32.0 40 48 A P - 0 0 86 0, 0.0 6,-0.3 0, 0.0 5,-0.1 -0.375 31.6-145.8 -61.8 133.9 1.2 -7.6 29.7 41 49 A G > - 0 0 25 4,-3.2 3,-1.8 6,-0.1 5,-0.1 0.025 40.1 -66.0 -84.5-162.1 -0.5 -4.3 28.9 42 50 A P T 3 S+ 0 0 122 0, 0.0 4,-0.1 0, 0.0 -1,-0.0 0.708 136.1 48.0 -60.4 -25.9 -4.2 -3.3 28.3 43 51 A D T 3 S- 0 0 60 2,-0.3 3,-0.1 3,-0.0 0, 0.0 0.289 121.2-106.5 -98.0 5.8 -4.3 -5.5 25.2 44 52 A G S < S+ 0 0 51 -3,-1.8 2,-0.3 1,-0.3 0, 0.0 0.392 89.8 105.5 84.9 -5.3 -2.7 -8.5 26.9 45 53 A N S S- 0 0 59 1,-0.1 -4,-3.2 -5,-0.1 -2,-0.3 -0.767 70.8-134.9-107.0 155.4 0.6 -7.9 25.1 46 54 A I S S+ 0 0 47 -2,-0.3 2,-0.3 -6,-0.3 -1,-0.1 0.946 90.8 36.2 -71.3 -47.7 3.8 -6.5 26.4 47 55 A F S S- 0 0 15 -10,-0.1 2,-0.2 -6,-0.1 165,-0.1 -0.770 80.7-124.0-109.3 151.8 4.5 -4.3 23.4 48 56 A C - 0 0 1 163,-0.4 163,-0.2 -2,-0.3 2,-0.1 -0.615 29.2-122.8 -90.3 148.7 2.1 -2.3 21.2 49 57 A G > - 0 0 3 3,-0.3 3,-0.5 -2,-0.2 159,-0.2 -0.313 25.7-103.7 -82.5 176.3 2.1 -2.8 17.5 50 58 A M T 3 S+ 0 0 11 157,-2.9 158,-0.1 1,-0.2 27,-0.1 0.715 120.3 49.5 -74.7 -20.0 2.7 -0.2 14.8 51 59 A L T 3 S+ 0 0 58 156,-0.4 -1,-0.2 1,-0.2 157,-0.1 0.525 118.8 38.2 -94.5 -8.0 -1.0 0.0 13.9 52 60 A N S < S+ 0 0 77 -3,-0.5 -3,-0.3 2,-0.0 -1,-0.2 -0.319 79.5 173.4-136.6 53.8 -2.1 0.4 17.5 53 61 A P + 0 0 10 0, 0.0 2,-0.2 0, 0.0 11,-0.1 -0.313 5.1 160.2 -66.8 142.4 0.5 2.6 19.2 54 62 A D > - 0 0 40 -5,-0.1 3,-2.2 9,-0.1 4,-0.3 -0.686 61.0 -56.1-139.6-162.9 -0.1 3.8 22.8 55 63 A K G > S+ 0 0 75 1,-0.3 3,-1.1 -2,-0.2 29,-0.2 0.755 126.5 66.9 -56.3 -26.0 2.0 5.1 25.7 56 64 A R G 3 S+ 0 0 12 1,-0.2 31,-2.5 30,-0.2 -1,-0.3 0.643 91.3 64.7 -68.9 -16.0 4.2 2.0 25.6 57 65 A S G < S+ 0 0 1 -3,-2.2 31,-0.5 29,-0.2 2,-0.4 0.668 101.2 52.4 -81.5 -16.3 5.5 3.1 22.2 58 66 A S S < S- 0 0 10 -3,-1.1 28,-1.5 -4,-0.3 2,-1.0 -0.963 71.1-131.0-134.7 142.5 7.2 6.2 23.4 59 67 A W B S-H 85 0B 36 29,-2.0 26,-0.2 -2,-0.4 31,-0.2 -0.732 90.0 -36.1 -87.1 102.0 9.7 7.5 25.9 60 68 A F S S+ 0 0 63 24,-3.5 2,-0.3 -2,-1.0 -1,-0.2 0.882 95.2 137.4 47.8 59.2 8.0 10.4 27.6 61 69 A K - 0 0 40 -3,-0.3 23,-0.2 21,-0.3 -1,-0.2 -0.893 52.7-138.2-123.1 156.8 6.1 12.0 24.6 62 70 A N S S+ 0 0 121 -2,-0.3 19,-2.0 1,-0.2 2,-0.3 0.385 86.8 32.4 -97.7 2.9 2.5 13.4 24.7 63 71 A R B S-I 80 0C 99 17,-0.3 17,-0.2 -9,-0.1 -1,-0.2 -0.971 82.6-113.2-157.3 141.1 1.5 12.0 21.3 64 72 A T - 0 0 3 15,-2.5 2,-0.3 -2,-0.3 14,-0.1 -0.276 30.2-144.5 -70.2 161.8 2.4 8.9 19.3 65 73 A E - 0 0 62 13,-0.1 3,-0.1 -8,-0.0 -1,-0.0 -0.953 14.5-112.0-130.9 150.0 4.3 9.2 16.0 66 74 A A - 0 0 20 -2,-0.3 5,-0.2 1,-0.1 3,-0.1 -0.547 43.9 -96.6 -80.6 142.0 4.2 7.3 12.8 67 75 A P > - 0 0 17 0, 0.0 3,-2.7 0, 0.0 4,-0.2 -0.359 58.3 -86.7 -56.5 136.6 7.2 5.1 11.8 68 76 A L T 3 S+ 0 0 40 1,-0.3 357,-0.1 2,-0.2 356,-0.0 -0.221 117.6 23.7 -50.3 125.7 9.4 7.1 9.5 69 77 A G T 3 S+ 0 0 1 355,-0.5 -1,-0.3 -3,-0.1 3,-0.2 0.111 112.2 72.5 102.0 -15.6 8.2 6.7 5.9 70 78 A S X> + 0 0 3 -3,-2.7 4,-3.2 1,-0.1 3,-1.4 0.247 52.7 112.8-117.1 15.7 4.6 5.8 6.8 71 79 A F H 3> S+ 0 0 105 353,-0.6 4,-1.7 1,-0.3 5,-0.2 0.857 74.2 61.2 -53.9 -41.2 3.1 9.0 8.0 72 80 A L H 34 S+ 0 0 79 352,-0.2 -1,-0.3 1,-0.2 -2,-0.1 0.762 120.7 23.6 -59.2 -27.3 0.7 9.2 5.1 73 81 A W H <4 S+ 0 0 56 -3,-1.4 -2,-0.2 2,-0.1 -1,-0.2 0.702 127.3 43.6-110.9 -28.7 -0.9 5.9 6.1 74 82 A L H >< S+ 0 0 2 -4,-3.2 3,-1.0 1,-0.2 4,-0.3 0.478 86.3 84.3-100.3 -2.6 -0.2 5.6 9.9 75 83 A D G >< S+ 0 0 58 -4,-1.7 3,-1.7 -5,-0.3 -1,-0.2 0.847 81.9 68.9 -66.9 -28.4 -0.9 9.1 11.1 76 84 A V G 3 S+ 0 0 108 1,-0.3 -1,-0.2 -5,-0.2 -2,-0.1 0.767 99.4 48.3 -59.1 -28.8 -4.6 8.1 11.3 77 85 A V G < S+ 0 0 29 -3,-1.0 -1,-0.3 -27,-0.1 -2,-0.2 0.469 86.1 115.7 -92.5 -1.2 -3.8 5.8 14.2 78 86 A N < + 0 0 5 -3,-1.7 2,-0.3 -4,-0.3 -13,-0.1 -0.401 42.0 178.4 -68.5 145.7 -1.8 8.4 16.2 79 87 A R - 0 0 144 -2,-0.1 -15,-2.5 -25,-0.0 2,-0.2 -0.965 34.9 -97.4-145.8 157.7 -3.2 9.4 19.5 80 88 A N B -I 63 0C 122 -2,-0.3 -17,-0.3 -17,-0.2 2,-0.3 -0.526 48.6-174.6 -73.2 143.8 -2.4 11.7 22.4 81 89 A I - 0 0 22 -19,-2.0 3,-0.0 -2,-0.2 -27,-0.0 -0.943 30.3-100.3-140.3 161.2 -0.7 9.8 25.3 82 90 A D - 0 0 118 -2,-0.3 -21,-0.3 1,-0.1 2,-0.2 -0.614 51.8 -99.4 -80.0 136.8 0.5 10.3 28.8 83 91 A P + 0 0 67 0, 0.0 2,-0.3 0, 0.0 -21,-0.1 -0.461 63.8 165.5 -56.0 126.6 4.3 10.8 29.0 84 92 A Y - 0 0 30 -26,-0.4 -24,-3.5 -29,-0.2 2,-2.6 -0.947 53.9 -93.3-145.9 162.2 5.4 7.3 30.0 85 93 A A B +H 59 0B 0 177,-1.7 -50,-0.3 -2,-0.3 -26,-0.2 -0.337 65.1 170.1 -75.8 58.6 8.5 5.1 30.2 86 94 A G - 0 0 0 -2,-2.6 -29,-0.2 -28,-1.5 -30,-0.2 -0.059 42.3-110.9 -65.4 175.7 7.9 3.7 26.7 87 95 A V S S+ 0 0 0 -31,-2.5 15,-2.3 124,-0.1 2,-0.5 0.743 92.9 57.5 -85.4 -28.4 10.2 1.6 24.7 88 96 A L E -J 101 0D 19 -31,-0.5 -29,-2.0 -32,-0.2 2,-0.5 -0.926 62.9-165.1-112.2 127.0 11.3 3.9 21.8 89 97 A D E -J 100 0D 13 11,-3.3 11,-2.6 -2,-0.5 2,-0.9 -0.928 8.9-161.7-116.0 118.9 12.9 7.3 22.3 90 98 A R E -J 99 0D 80 -2,-0.5 2,-0.7 9,-0.2 9,-0.2 -0.871 16.2-158.5 -95.3 105.1 13.2 9.9 19.6 91 99 A V E -J 98 0D 26 7,-3.2 7,-2.6 -2,-0.9 2,-0.7 -0.817 7.0-149.4 -89.8 115.0 16.0 12.2 20.9 92 100 A N E +J 97 0D 90 -2,-0.7 5,-0.2 5,-0.2 2,-0.2 -0.775 20.2 174.1 -93.7 115.3 15.7 15.5 19.2 93 101 A Y - 0 0 42 3,-3.0 3,-0.5 -2,-0.7 299,-0.1 -0.528 52.7 -79.2-104.0 177.6 18.9 17.5 18.7 94 102 A D S S- 0 0 110 297,-0.4 298,-0.1 1,-0.2 300,-0.1 0.889 121.3 -4.9 -44.8 -55.1 19.2 20.8 16.8 95 103 A Q S S+ 0 0 46 298,-0.5 2,-0.3 296,-0.3 -1,-0.2 -0.010 126.6 65.2-135.4 32.7 19.2 19.3 13.3 96 104 A M - 0 0 3 -3,-0.5 -3,-3.0 295,-0.1 2,-0.6 -0.970 56.8-155.0-157.4 135.0 19.2 15.5 14.0 97 105 A S E -Jk 92 436D 14 338,-1.7 340,-1.8 -2,-0.3 2,-0.5 -0.965 15.2-162.9-115.2 114.3 16.7 13.1 15.6 98 106 A V E -Jk 91 437D 0 -7,-2.6 -7,-3.2 -2,-0.6 2,-0.5 -0.884 6.7-149.4-102.2 124.6 18.3 10.0 17.0 99 107 A Y E +J 90 0D 28 338,-3.1 2,-0.3 -2,-0.5 -9,-0.2 -0.796 25.3 166.7 -94.4 127.9 16.1 7.0 17.7 100 108 A V E -J 89 0D 29 -11,-2.6 -11,-3.3 -2,-0.5 2,-0.2 -0.982 33.5-112.4-140.6 152.2 17.1 4.7 20.6 101 109 A G E -J 88 0D 10 -2,-0.3 2,-0.4 -13,-0.2 6,-0.3 -0.536 21.2-157.9 -83.3 149.7 15.6 1.9 22.7 102 110 A R + 0 0 37 -15,-2.3 -67,-0.5 4,-0.3 2,-0.3 -0.954 52.1 51.0-130.5 111.1 14.9 2.4 26.4 103 111 A G S > S- 0 0 0 -2,-0.4 3,-2.6 -69,-0.3 2,-0.9 -0.869 98.9 -34.8 150.5 176.0 14.6 -0.7 28.6 104 112 A V T 3 S+ 0 0 3 -69,-2.5 117,-0.3 1,-0.3 -67,-0.3 -0.557 133.3 27.0 -68.4 105.8 16.3 -4.0 29.5 105 113 A G T > S- 0 0 0 -2,-0.9 3,-1.9 -95,-0.3 115,-0.3 0.179 95.9-148.4 122.8 -11.0 18.0 -4.9 26.3 106 114 A G G X S- 0 0 8 -3,-2.6 3,-1.8 1,-0.3 4,-0.5 -0.182 73.1 -1.0 53.9-133.6 18.3 -1.4 24.9 107 115 A G G >> S+ 0 0 28 -6,-0.3 4,-2.0 1,-0.3 3,-0.5 0.684 120.3 76.7 -62.0 -20.3 18.1 -1.0 21.1 108 116 A S G <4 S+ 0 0 0 -3,-1.9 -1,-0.3 1,-0.2 -2,-0.2 0.722 89.9 59.4 -64.0 -19.4 17.7 -4.8 20.8 109 117 A L G <4 S+ 0 0 2 -3,-1.8 104,-0.3 -4,-0.2 -1,-0.2 0.868 118.5 25.1 -75.2 -36.9 14.1 -4.3 21.9 110 118 A V T <4 S+ 0 0 16 -3,-0.5 -2,-0.2 -4,-0.5 102,-0.2 0.504 98.5 106.9-107.8 -6.6 13.2 -2.0 19.0 111 119 A N S < S- 0 0 35 -4,-2.0 101,-0.1 1,-0.1 100,-0.0 -0.179 77.3-114.0 -77.4 166.7 15.6 -2.9 16.2 112 120 A G - 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0 0 132 -3,-0.9 -3,-0.2 -4,-0.6 70,-0.1 0.870 37.6-173.0 68.3 40.4 21.4 -16.4 18.0 149 157 A V < + 0 0 18 -5,-2.0 2,-0.3 -6,-0.2 37,-0.2 -0.417 6.8 176.7 -64.7 136.0 21.7 -15.2 14.5 150 158 A N B -M 185 0E 39 35,-2.8 35,-2.2 37,-0.2 2,-0.4 -0.858 22.7-120.3-136.7 172.7 19.8 -17.3 12.0 151 159 A H - 0 0 126 -2,-0.3 2,-0.0 33,-0.2 38,-0.0 -0.947 24.2-112.9-124.7 141.7 19.1 -17.3 8.2 152 160 A I - 0 0 16 -2,-0.4 2,-0.5 31,-0.2 38,-0.0 -0.327 34.9-107.9 -69.8 144.6 15.8 -17.2 6.3 153 161 A D > - 0 0 77 1,-0.2 4,-2.7 36,-0.1 5,-0.2 -0.645 24.8-149.2 -73.1 121.8 14.7 -20.2 4.2 154 162 A T H > S+ 0 0 83 -2,-0.5 4,-2.2 2,-0.2 -1,-0.2 0.845 94.2 51.6 -63.1 -36.6 15.2 -19.2 0.6 155 163 A K H > S+ 0 0 152 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.935 113.4 44.3 -66.8 -45.4 12.3 -21.4 -0.7 156 164 A W H > S+ 0 0 34 1,-0.2 4,-2.7 2,-0.2 3,-0.2 0.932 113.0 51.5 -63.6 -46.0 9.9 -19.9 1.8 157 165 A F H < S+ 0 0 0 -4,-2.7 -1,-0.2 1,-0.2 -2,-0.2 0.895 109.7 50.9 -56.5 -42.5 11.2 -16.4 1.1 158 166 A E H < S+ 0 0 77 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.834 119.0 35.0 -66.4 -33.6 10.6 -16.9 -2.6 159 167 A D H < S+ 0 0 114 -4,-1.6 -2,-0.2 -3,-0.2 -1,-0.2 0.741 92.6 100.6 -95.4 -26.6 7.0 -18.1 -2.3 160 168 A T >< - 0 0 13 -4,-2.7 3,-1.3 -5,-0.2 33,-0.0 -0.365 62.3-144.9 -70.6 138.1 5.6 -16.1 0.6 161 169 A E G > S+ 0 0 103 1,-0.2 3,-1.4 2,-0.2 4,-0.3 0.762 96.1 74.5 -67.0 -23.1 3.4 -13.0 0.1 162 170 A W G 3 S+ 0 0 28 1,-0.3 171,-2.6 170,-0.1 -1,-0.2 0.600 101.9 38.4 -67.2 -13.8 5.1 -11.5 3.2 163 171 A Y G <> S+ 0 0 0 -3,-1.3 4,-1.9 -6,-0.2 3,-0.4 0.124 77.7 109.3-123.9 20.7 8.2 -10.8 1.2 164 172 A K H <> S+ 0 0 57 -3,-1.4 4,-2.5 167,-0.4 5,-0.2 0.905 76.9 60.7 -62.3 -37.4 6.8 -9.7 -2.1 165 173 A F H > S+ 0 0 5 163,-0.5 4,-1.4 -4,-0.3 -1,-0.2 0.865 106.0 47.4 -56.8 -36.6 8.0 -6.2 -1.3 166 174 A A H > S+ 0 0 1 -3,-0.4 4,-1.9 2,-0.2 -1,-0.2 0.902 110.7 50.0 -71.5 -43.4 11.6 -7.5 -1.1 167 175 A R H X S+ 0 0 45 -4,-1.9 4,-2.2 2,-0.2 -2,-0.2 0.848 106.5 55.9 -64.9 -36.8 11.3 -9.5 -4.4 168 176 A V H X S+ 0 0 16 -4,-2.5 4,-2.3 1,-0.2 -1,-0.2 0.946 110.2 44.6 -61.9 -47.5 10.0 -6.4 -6.3 169 177 A S H X S+ 0 0 1 -4,-1.4 4,-2.9 2,-0.2 5,-0.2 0.854 110.2 55.7 -65.8 -35.1 13.0 -4.3 -5.3 170 178 A R H X S+ 0 0 73 -4,-1.9 4,-2.3 2,-0.2 -1,-0.2 0.939 110.4 45.3 -61.2 -46.5 15.4 -7.2 -6.1 171 179 A E H X S+ 0 0 75 -4,-2.2 4,-1.1 2,-0.2 -2,-0.2 0.908 114.4 48.5 -63.0 -44.3 13.9 -7.3 -9.6 172 180 A Q H X S+ 0 0 2 -4,-2.3 4,-0.6 1,-0.2 3,-0.4 0.911 112.9 47.1 -64.2 -43.4 14.0 -3.5 -10.0 173 181 A A H ><>S+ 0 0 0 -4,-2.9 5,-2.4 1,-0.2 3,-1.3 0.883 104.7 62.2 -66.2 -37.4 17.6 -3.3 -8.8 174 182 A G H ><5S+ 0 0 44 -4,-2.3 3,-1.5 1,-0.3 -1,-0.2 0.819 96.3 58.5 -57.8 -33.9 18.6 -6.2 -11.1 175 183 A K H 3<5S+ 0 0 133 -4,-1.1 -1,-0.3 -3,-0.4 -2,-0.2 0.736 104.3 51.5 -68.3 -23.8 17.7 -4.1 -14.1 176 184 A A T <<5S- 0 0 19 -3,-1.3 -1,-0.3 -4,-0.6 -2,-0.2 0.238 125.4-104.8 -94.1 9.4 20.2 -1.5 -13.0 177 185 A G T < 5S+ 0 0 70 -3,-1.5 2,-0.4 1,-0.3 -3,-0.2 0.696 79.4 134.3 74.7 21.3 22.8 -4.2 -12.7 178 186 A L < - 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