==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 29-OCT-07 3B6D . COMPND 2 MOLECULE: CHOLESTEROL OXIDASE; . SOURCE 2 ORGANISM_SCIENTIFIC: STREPTOMYCES SP.; . AUTHOR A.Y.LYUBIMOV,A.VRIELINK . 498 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 18178.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 332 66.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 26 5.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 77 15.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 5 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 41 8.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 45 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 102 20.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 14 2.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 2 2 1 1 0 0 2 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 1 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 9 2 1 2 1 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 2 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 9 A G 0 0 70 0, 0.0 272,-2.7 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0-172.1 25.9 1.1 48.4 2 10 A Y E +a 273 0A 132 270,-0.2 272,-0.2 252,-0.0 3,-0.1 -0.753 360.0 171.5-100.9 138.7 29.1 -0.7 47.0 3 11 A V E -a 274 0A 22 270,-2.1 272,-0.5 -2,-0.3 273,-0.2 -0.980 37.6-125.3-139.5 137.3 29.2 -3.3 44.3 4 12 A P E S+ 0 0 38 0, 0.0 272,-2.3 0, 0.0 271,-2.2 0.911 94.6 18.6 -51.3 -49.6 32.5 -4.5 42.8 5 13 A A E -ab 276 28A 0 22,-2.0 24,-2.4 270,-0.2 2,-0.4 -0.980 65.4-167.4-124.5 138.6 31.4 -3.7 39.2 6 14 A V E -ab 277 29A 0 270,-2.1 272,-2.8 -2,-0.4 2,-0.5 -0.987 3.4-163.9-118.1 137.7 28.7 -1.5 37.9 7 15 A V E -ab 278 30A 0 22,-2.5 24,-2.4 -2,-0.4 2,-0.6 -0.988 12.9-145.8-116.4 122.8 27.5 -1.5 34.3 8 16 A I E +ab 279 31A 9 270,-2.8 272,-2.3 -2,-0.5 24,-0.2 -0.816 67.2 5.9 -91.5 119.6 25.5 1.5 33.1 9 17 A G - 0 0 8 22,-3.2 22,-0.2 -2,-0.6 272,-0.2 -0.134 66.5-120.9 95.6 170.0 22.8 0.5 30.6 10 18 A T + 0 0 0 93,-0.3 95,-0.4 270,-0.1 -1,-0.1 -0.042 67.4 111.6-145.1 31.0 21.7 -2.9 29.3 11 19 A G S > S- 0 0 13 269,-0.7 4,-2.7 94,-0.1 5,-0.2 0.064 87.7 -61.6 -82.4-158.0 22.2 -2.7 25.5 12 20 A Y H > S+ 0 0 22 1,-0.2 4,-2.1 2,-0.2 5,-0.3 0.934 133.1 41.7 -64.2 -50.9 24.8 -4.7 23.5 13 21 A G H > S+ 0 0 1 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.913 118.4 47.6 -63.1 -42.3 28.0 -3.4 25.0 14 22 A A H > S+ 0 0 0 266,-0.4 4,-2.8 2,-0.2 -2,-0.2 0.904 110.7 50.6 -62.8 -43.9 26.6 -3.6 28.5 15 23 A A H X S+ 0 0 0 -4,-2.7 4,-2.1 2,-0.2 5,-0.2 0.906 111.8 46.8 -68.2 -42.8 25.1 -7.1 28.1 16 24 A V H X S+ 0 0 0 -4,-2.1 4,-2.1 -5,-0.2 5,-0.2 0.948 113.7 49.1 -60.7 -47.3 28.3 -8.6 26.8 17 25 A S H X S+ 0 0 2 -4,-2.0 4,-2.6 -5,-0.3 5,-0.2 0.931 111.6 47.9 -60.6 -49.4 30.3 -6.9 29.6 18 26 A A H X S+ 0 0 0 -4,-2.8 4,-2.4 1,-0.2 -1,-0.2 0.894 110.0 52.3 -61.8 -40.9 28.0 -8.1 32.4 19 27 A L H X S+ 0 0 1 -4,-2.1 4,-2.5 -5,-0.2 -1,-0.2 0.963 113.7 42.7 -58.1 -48.9 27.9 -11.7 31.1 20 28 A R H X S+ 0 0 38 -4,-2.1 4,-1.5 1,-0.2 -2,-0.2 0.903 113.0 52.5 -73.6 -35.1 31.7 -12.0 31.0 21 29 A L H <>S+ 0 0 0 -4,-2.6 5,-2.5 -5,-0.2 4,-0.3 0.934 111.7 47.1 -60.6 -45.2 32.1 -10.3 34.3 22 30 A G H ><5S+ 0 0 4 -4,-2.4 3,-1.5 1,-0.2 -2,-0.2 0.912 109.5 51.8 -63.6 -40.3 29.7 -12.6 35.9 23 31 A E H 3<5S+ 0 0 112 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.778 106.6 55.1 -64.2 -28.7 31.3 -15.6 34.4 24 32 A A T 3<5S- 0 0 53 -4,-1.5 -1,-0.3 -3,-0.3 -2,-0.2 0.402 123.2-108.3 -82.5 -2.8 34.7 -14.3 35.9 25 33 A G T < 5S+ 0 0 41 -3,-1.5 2,-0.7 -4,-0.3 -3,-0.2 0.618 71.2 143.6 86.0 15.3 33.0 -14.2 39.3 26 34 A V < - 0 0 17 -5,-2.5 -1,-0.3 -6,-0.2 2,-0.2 -0.776 53.2-126.7 -90.4 117.7 32.8 -10.5 39.6 27 35 A Q - 0 0 75 -2,-0.7 -22,-2.0 -3,-0.1 2,-0.4 -0.503 37.6-169.8 -66.4 126.2 29.6 -9.3 41.3 28 36 A T E -bc 5 234A 0 205,-2.8 207,-2.1 -2,-0.2 2,-0.5 -0.972 21.3-160.3-131.8 131.4 28.0 -6.9 38.9 29 37 A L E -bc 6 235A 3 -24,-2.4 -22,-2.5 -2,-0.4 2,-0.4 -0.971 10.6-156.8-112.3 124.8 25.1 -4.5 39.1 30 38 A M E -bc 7 236A 0 205,-3.0 207,-2.7 -2,-0.5 2,-0.5 -0.863 4.4-156.6 -97.5 133.2 23.5 -3.2 35.9 31 39 A L E -bc 8 237A 2 -24,-2.4 -22,-3.2 -2,-0.4 2,-0.5 -0.958 13.1-178.8-113.2 119.0 21.6 0.1 36.1 32 40 A E E - c 0 238A 13 205,-2.5 208,-2.3 -2,-0.5 207,-0.6 -0.970 22.4-155.6-122.1 128.8 19.0 0.7 33.4 33 41 A M S S+ 0 0 32 -2,-0.5 208,-0.2 206,-0.3 227,-0.1 0.756 78.2 59.4 -74.8 -27.0 16.9 3.9 33.2 34 42 A G S S- 0 0 0 1,-0.1 205,-2.1 206,-0.1 206,-0.3 -0.147 92.6 -78.9 -88.5-169.9 14.0 2.1 31.3 35 43 A Q - 0 0 25 67,-0.4 69,-2.5 50,-0.4 2,-0.7 -0.470 28.8-113.2 -88.6 158.4 11.8 -0.7 32.3 36 44 A L - 0 0 77 67,-0.2 2,-1.6 -2,-0.2 3,-0.3 -0.857 39.0-138.6 -79.6 115.7 12.0 -4.5 32.3 37 45 A W + 0 0 17 -2,-0.7 9,-0.1 67,-0.3 10,-0.1 -0.599 68.7 104.7 -90.0 85.1 9.5 -5.3 29.6 38 46 A N + 0 0 84 -2,-1.6 -1,-0.2 8,-0.1 8,-0.1 0.299 46.2 101.2-143.8 12.8 7.7 -8.3 31.0 39 47 A Q S S- 0 0 130 -3,-0.3 6,-0.1 7,-0.1 -1,-0.0 -0.904 70.7-124.4-105.7 113.9 4.2 -6.9 32.1 40 48 A P - 0 0 87 0, 0.0 6,-0.3 0, 0.0 5,-0.1 -0.353 32.3-146.2 -57.7 137.1 1.3 -7.5 29.9 41 49 A G > - 0 0 26 4,-3.1 3,-2.3 6,-0.1 6,-0.1 0.033 40.6 -61.8 -90.5-164.1 -0.5 -4.2 29.1 42 50 A P T 3 S+ 0 0 120 0, 0.0 4,-0.1 0, 0.0 -1,-0.0 0.738 135.7 46.0 -57.7 -29.0 -4.1 -3.2 28.5 43 51 A D T 3 S- 0 0 61 2,-0.3 3,-0.1 3,-0.0 0, 0.0 0.203 120.7-103.7 -99.9 10.4 -4.3 -5.4 25.4 44 52 A G S < S+ 0 0 50 -3,-2.3 2,-0.3 1,-0.3 0, 0.0 0.379 91.2 104.9 80.7 -3.1 -2.7 -8.4 27.1 45 53 A N S S- 0 0 59 1,-0.1 -4,-3.1 -5,-0.1 -2,-0.3 -0.759 70.4-135.0-107.7 156.3 0.6 -7.9 25.3 46 54 A I S S+ 0 0 33 -2,-0.3 2,-0.3 -6,-0.3 -1,-0.1 0.978 89.6 36.3 -67.1 -53.5 3.8 -6.5 26.5 47 55 A F S S- 0 0 16 -10,-0.1 2,-0.3 -6,-0.1 165,-0.1 -0.692 79.1-123.9-106.4 149.1 4.4 -4.2 23.6 48 56 A C - 0 0 1 163,-0.4 163,-0.2 -2,-0.3 2,-0.1 -0.665 28.9-126.2 -85.1 147.9 2.1 -2.1 21.3 49 57 A G > - 0 0 3 -2,-0.3 3,-0.8 3,-0.2 159,-0.2 -0.301 26.5-102.1 -83.6 174.7 2.2 -2.7 17.6 50 58 A M T 3 S+ 0 0 11 157,-2.8 158,-0.1 1,-0.2 27,-0.1 0.737 121.7 49.8 -75.5 -21.8 2.7 -0.1 14.9 51 59 A L T 3 S+ 0 0 71 156,-0.4 -1,-0.2 155,-0.2 157,-0.1 0.426 118.8 38.3 -90.5 -6.0 -1.0 0.1 14.0 52 60 A N S < S+ 0 0 76 -3,-0.8 -3,-0.2 2,-0.0 -1,-0.2 -0.279 77.6 173.5-137.5 56.2 -2.1 0.5 17.7 53 61 A P + 0 0 11 0, 0.0 2,-0.2 0, 0.0 11,-0.1 -0.317 6.0 160.6 -66.7 142.9 0.5 2.8 19.4 54 62 A D > - 0 0 41 9,-0.1 3,-2.2 -5,-0.1 4,-0.2 -0.666 61.5 -58.5-139.7-162.0 -0.2 3.8 23.0 55 63 A K G > S+ 0 0 74 1,-0.3 3,-1.4 -2,-0.2 31,-0.2 0.767 126.6 68.2 -60.9 -23.9 2.0 5.2 25.8 56 64 A R G 3 S+ 0 0 8 1,-0.3 31,-2.5 30,-0.2 -1,-0.3 0.658 90.9 64.9 -67.2 -16.7 4.2 2.1 25.7 57 65 A S G < S+ 0 0 1 -3,-2.2 2,-0.4 29,-0.2 31,-0.4 0.649 101.4 51.3 -77.6 -17.2 5.5 3.2 22.3 58 66 A S S < S- 0 0 10 -3,-1.4 28,-1.3 -4,-0.2 2,-0.9 -0.980 70.7-130.6-139.2 133.6 7.2 6.4 23.5 59 67 A W B S-H 85 0B 35 29,-2.0 26,-0.2 -2,-0.4 31,-0.2 -0.748 90.7 -34.2 -81.0 102.8 9.7 7.6 26.1 60 68 A F S S+ 0 0 65 24,-3.0 2,-0.3 -2,-0.9 -1,-0.2 0.882 97.4 138.1 49.2 58.1 8.0 10.6 27.8 61 69 A K - 0 0 39 -3,-0.3 23,-0.2 21,-0.3 -1,-0.2 -0.886 51.4-142.0-118.7 155.7 6.1 12.0 24.8 62 70 A N S S+ 0 0 121 -2,-0.3 19,-1.7 1,-0.2 2,-0.3 0.403 84.8 32.8-102.0 5.8 2.6 13.4 24.8 63 71 A R B S-I 80 0C 99 17,-0.3 17,-0.2 -9,-0.1 -1,-0.2 -0.972 82.1-115.1-154.6 141.3 1.5 12.0 21.4 64 72 A T - 0 0 2 15,-2.5 2,-0.3 -2,-0.3 -9,-0.1 -0.328 30.3-144.7 -68.5 159.8 2.4 8.9 19.4 65 73 A E - 0 0 69 13,-0.1 3,-0.1 -8,-0.1 -1,-0.0 -0.934 14.3-112.2-125.2 150.2 4.3 9.2 16.1 66 74 A A - 0 0 21 -2,-0.3 5,-0.2 1,-0.1 3,-0.1 -0.597 44.2 -96.3 -73.2 144.2 4.2 7.3 12.9 67 75 A P > - 0 0 16 0, 0.0 3,-2.7 0, 0.0 4,-0.3 -0.284 57.6 -88.0 -57.8 137.9 7.2 5.2 12.0 68 76 A L T 3 S+ 0 0 42 1,-0.3 357,-0.1 2,-0.2 356,-0.0 -0.354 118.1 25.3 -57.5 131.1 9.4 7.3 9.6 69 77 A G T 3 S+ 0 0 1 355,-0.6 -1,-0.3 -3,-0.1 3,-0.2 0.013 112.3 74.2 102.5 -19.8 8.2 6.8 6.0 70 78 A S X> + 0 0 3 -3,-2.7 4,-2.6 1,-0.1 3,-2.0 0.367 53.2 108.7-109.3 -2.0 4.7 5.8 7.1 71 79 A F H 3> S+ 0 0 107 353,-0.5 4,-1.7 -4,-0.3 5,-0.2 0.815 74.6 61.7 -51.0 -37.2 3.1 9.1 8.2 72 80 A L H 34 S+ 0 0 79 352,-0.3 -1,-0.3 1,-0.2 -2,-0.1 0.788 120.9 23.2 -61.3 -25.7 0.8 9.2 5.1 73 81 A W H <4 S+ 0 0 57 -3,-2.0 -2,-0.2 2,-0.1 -1,-0.2 0.683 127.7 42.4-111.9 -26.2 -0.9 5.9 6.2 74 82 A L H >< S+ 0 0 4 -4,-2.6 3,-1.4 1,-0.1 4,-0.4 0.484 85.3 85.6-106.5 -6.6 -0.3 5.7 10.0 75 83 A D G >< S+ 0 0 57 -4,-1.7 3,-1.9 -5,-0.4 -1,-0.1 0.878 82.2 69.6 -60.0 -28.8 -0.9 9.2 11.2 76 84 A V G 3 S+ 0 0 109 1,-0.3 -1,-0.3 -5,-0.2 -2,-0.1 0.731 98.8 48.0 -61.7 -22.0 -4.6 8.1 11.4 77 85 A V G < S+ 0 0 37 -3,-1.4 -1,-0.3 -27,-0.1 -2,-0.2 0.475 86.0 116.2 -97.4 1.1 -3.8 5.8 14.3 78 86 A N < + 0 0 6 -3,-1.9 2,-0.3 -4,-0.4 -13,-0.1 -0.376 41.5 178.2 -70.6 148.8 -1.8 8.4 16.3 79 87 A R - 0 0 142 -2,-0.1 -15,-2.5 -25,-0.0 2,-0.2 -0.974 35.3 -96.9-145.9 155.6 -3.2 9.5 19.6 80 88 A N B -I 63 0C 121 -2,-0.3 2,-0.3 -17,-0.2 -17,-0.3 -0.502 48.7-176.1 -67.4 142.2 -2.4 11.7 22.6 81 89 A I - 0 0 25 -19,-1.7 3,-0.0 -2,-0.2 -27,-0.0 -0.945 30.2-101.2-139.6 158.9 -0.8 9.8 25.4 82 90 A D - 0 0 113 -2,-0.3 -21,-0.3 1,-0.1 2,-0.2 -0.598 50.1 -99.7 -75.0 139.3 0.5 10.3 28.9 83 91 A P + 0 0 63 0, 0.0 2,-0.3 0, 0.0 -21,-0.1 -0.453 62.8 161.2 -60.3 133.2 4.2 10.8 29.2 84 92 A Y - 0 0 30 -26,-0.4 -24,-3.0 -29,-0.2 2,-2.4 -0.963 55.4 -91.6-153.5 157.9 5.4 7.4 30.3 85 93 A A B +H 59 0B 0 177,-1.9 -50,-0.4 -2,-0.3 -26,-0.2 -0.325 65.7 165.5 -77.7 61.7 8.6 5.2 30.4 86 94 A G - 0 0 0 -2,-2.4 -29,-0.2 -28,-1.3 -30,-0.2 -0.046 45.4-104.4 -77.6-176.4 7.8 3.7 27.0 87 95 A V S S+ 0 0 0 -31,-2.5 15,-2.3 124,-0.1 2,-0.5 0.727 93.5 55.5 -94.4 -21.4 10.2 1.7 24.8 88 96 A L E -J 101 0D 21 -31,-0.4 -29,-2.0 13,-0.2 2,-0.6 -0.948 61.1-164.7-120.6 124.5 11.3 4.0 22.0 89 97 A D E -J 100 0D 14 11,-3.0 11,-2.1 -2,-0.5 2,-0.8 -0.927 8.6-158.9-113.5 115.1 12.9 7.5 22.6 90 98 A R E -J 99 0D 76 -2,-0.6 2,-0.6 9,-0.2 9,-0.2 -0.845 16.3-159.7 -86.7 112.5 13.2 10.0 19.8 91 99 A V E -J 98 0D 14 7,-3.3 7,-2.7 -2,-0.8 2,-0.6 -0.886 6.4-151.4 -99.4 114.6 16.0 12.3 21.0 92 100 A N E +J 97 0D 84 -2,-0.6 5,-0.2 5,-0.2 2,-0.2 -0.760 18.4 174.8-100.7 120.4 15.8 15.7 19.3 93 101 A Y - 0 0 26 3,-2.9 3,-0.5 -2,-0.6 299,-0.1 -0.526 53.5 -82.1-105.6 178.9 18.9 17.7 18.8 94 102 A D S S+ 0 0 122 297,-0.4 298,-0.1 1,-0.2 300,-0.1 0.894 121.4 1.6 -60.9 -39.0 19.0 21.0 16.8 95 103 A Q S S+ 0 0 52 298,-0.4 2,-0.3 296,-0.3 -1,-0.2 0.087 126.7 58.6-136.9 30.6 19.3 19.4 13.3 96 104 A M - 0 0 3 -3,-0.5 -3,-2.9 295,-0.1 2,-0.5 -0.955 57.2-155.0-157.4 136.2 19.2 15.6 14.1 97 105 A S E -Jk 92 436D 14 338,-2.0 340,-1.8 -2,-0.3 2,-0.5 -0.976 15.7-163.1-115.4 119.8 16.7 13.3 15.7 98 106 A V E -Jk 91 437D 0 -7,-2.7 -7,-3.3 -2,-0.5 2,-0.4 -0.904 6.2-149.3-107.3 128.2 18.3 10.1 17.1 99 107 A Y E +J 90 0D 35 338,-2.8 2,-0.3 -2,-0.5 -9,-0.2 -0.822 23.2 169.0-101.1 128.5 16.1 7.1 18.0 100 108 A V E -J 89 0D 30 -11,-2.1 -11,-3.0 -2,-0.4 2,-0.2 -0.980 32.5-111.2-138.7 152.9 17.1 4.8 20.8 101 109 A G E -J 88 0D 11 -2,-0.3 2,-0.4 -13,-0.2 6,-0.3 -0.509 22.3-157.5 -79.7 149.4 15.7 2.0 22.9 102 110 A R + 0 0 36 -15,-2.3 -67,-0.4 4,-0.3 2,-0.3 -0.924 51.6 50.1-132.4 108.1 14.8 2.4 26.5 103 111 A G S > S- 0 0 0 -2,-0.4 3,-2.7 -69,-0.3 2,-0.7 -0.892 98.8 -35.2 153.8 176.1 14.6 -0.7 28.7 104 112 A V T 3 S+ 0 0 3 -69,-2.5 117,-0.3 1,-0.3 -67,-0.3 -0.558 132.8 27.3 -67.1 109.9 16.3 -3.9 29.7 105 113 A G T > S- 0 0 0 -2,-0.7 3,-1.9 -95,-0.4 115,-0.3 0.244 96.0-146.1 113.6 -12.2 18.0 -4.8 26.4 106 114 A G G X S- 0 0 8 -3,-2.7 3,-1.9 1,-0.3 4,-0.4 -0.148 73.3 -3.7 55.2-136.8 18.3 -1.3 25.0 107 115 A G G >> S+ 0 0 27 -6,-0.3 4,-1.7 1,-0.3 3,-0.8 0.690 120.0 79.0 -67.5 -15.8 18.0 -1.0 21.2 108 116 A S G <4 S+ 0 0 1 -3,-1.9 -1,-0.3 1,-0.2 -2,-0.2 0.748 89.0 59.0 -61.1 -21.7 17.7 -4.7 20.9 109 117 A L G <4 S+ 0 0 2 -3,-1.9 104,-0.3 -4,-0.2 -1,-0.2 0.854 119.3 24.3 -69.4 -35.2 14.0 -4.2 22.0 110 118 A V T <4 S+ 0 0 14 -3,-0.8 -2,-0.2 -4,-0.4 -1,-0.2 0.442 97.5 105.1-114.6 -7.5 13.2 -1.9 19.1 111 119 A N S < S- 0 0 36 -4,-1.7 101,-0.1 1,-0.1 100,-0.0 -0.199 77.8-111.2 -84.2 172.5 15.6 -2.7 16.3 112 120 A G - 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0 0 56 4,-2.2 3,-1.5 -2,-0.3 -4,-1.1 -0.124 61.7 -77.9 -76.7-171.2 42.7 3.0 24.6 452 460 A D T 3 S+ 0 0 28 1,-0.3 -6,-0.1 -6,-0.2 -1,-0.1 0.479 132.6 46.4 -76.9 3.8 42.2 0.2 22.0 453 461 A Y T 3 S- 0 0 55 2,-0.1 -1,-0.3 36,-0.0 40,-0.1 0.169 123.8 -94.2-125.6 13.2 40.1 -1.7 24.5 454 462 A G S < S+ 0 0 0 -3,-1.5 10,-2.5 1,-0.3 2,-0.5 0.556 70.4 150.8 84.4 8.7 37.8 1.0 25.7 455 463 A R B -G 463 0A 46 8,-0.2 -4,-2.2 1,-0.1 -1,-0.3 -0.641 52.9-117.3 -73.0 123.0 39.7 2.0 28.8 456 464 A V B > -X 450 0K 2 6,-2.6 3,-1.8 -2,-0.5 -6,-0.3 -0.387 30.5-111.2 -67.2 128.1 38.9 5.7 29.2 457 465 A A T 3 S+ 0 0 35 -8,-2.2 -154,-0.4 1,-0.2 -1,-0.1 -0.349 100.0 25.0 -64.0 137.2 42.0 7.9 28.9 458 466 A G T 3 S+ 0 0 42 1,-0.2 2,-0.3 -156,-0.1 -1,-0.2 0.238 112.0 77.8 97.8 -11.3 43.1 9.5 32.1 459 467 A Y < - 0 0 31 -3,-1.8 2,-0.4 3,-0.2 3,-0.3 -0.945 66.6-134.8-137.5 150.0 41.5 6.9 34.4 460 468 A K S S+ 0 0 137 -2,-0.3 -208,-0.1 1,-0.2 3,-0.1 -0.819 89.0 8.2-100.6 139.3 42.0 3.4 35.8 461 469 A N S S+ 0 0 16 -2,-0.4 -184,-2.2 1,-0.2 2,-0.4 0.759 94.8 121.8 61.1 30.4 39.2 0.8 35.8 462 470 A L E +f 277 0A 0 -3,-0.3 -6,-2.6 -186,-0.2 2,-0.3 -0.996 39.9 180.0-125.8 120.1 36.9 3.0 33.9 463 471 A Y E -fG 278 455A 2 -186,-2.8 -184,-3.2 -2,-0.4 2,-0.4 -0.906 26.2-154.1-132.0 144.7 35.6 1.5 30.6 464 472 A V E +f 279 0A 2 -10,-2.5 -184,-0.2 -2,-0.3 -2,-0.0 -0.970 18.0 172.5-116.0 139.1 33.3 2.4 27.7 465 473 A T + 0 0 8 -186,-2.4 -185,-0.2 -2,-0.4 25,-0.1 0.384 43.8 66.1-127.1 -0.4 31.8 -0.6 25.9 466 474 A D S > S- 0 0 7 -187,-0.4 3,-2.2 -184,-0.1 4,-0.3 -0.129 98.3 -54.3-124.8-161.8 29.2 0.5 23.4 467 475 A G G > S+ 0 0 5 1,-0.3 -25,-2.4 2,-0.2 3,-1.1 0.645 114.6 77.2 -60.0 -18.6 28.4 2.3 20.1 468 476 A S G 3 S+ 0 0 0 -27,-0.2 -24,-2.5 1,-0.2 -1,-0.3 0.716 88.5 62.0 -61.1 -18.8 30.2 5.4 21.4 469 477 A L G < S+ 0 0 2 -3,-2.2 -23,-2.7 -24,-0.2 -1,-0.2 0.698 83.0 89.8 -75.4 -25.0 33.5 3.5 20.6 470 478 A I S < S- 0 0 1 -3,-1.1 2,-2.3 -4,-0.3 -26,-0.2 -0.626 85.0-118.1 -88.2 138.0 32.9 3.2 16.9 471 479 A P - 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