==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=16-AUG-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE 14-AUG-12 4B6L . COMPND 2 MOLECULE: SERINE/THREONINE-PROTEIN KINASE PLK3; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR K.BROWN,J.D.CHARRIER,S.DURRANT,M.GRIFFITHS,C.HUDSON,D.KAY,R. . 281 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13652.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 174 61.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 41 14.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 18 6.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 28 10.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 78 27.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 0 0 1 1 1 0 0 0 1 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 2 1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 52 A L 0 0 154 0, 0.0 12,-3.6 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0-156.3 51.7 -19.7 -17.5 2 53 A I E -A 12 0A 83 10,-0.2 2,-0.3 26,-0.0 10,-0.2 -0.849 360.0-161.4-111.2 147.3 48.0 -18.6 -18.0 3 54 A T E +A 11 0A 1 8,-2.6 8,-2.1 -2,-0.3 0, 0.0 -0.934 17.1 175.1-118.5 142.6 45.2 -17.3 -15.6 4 55 A D - 0 0 71 -2,-0.3 6,-0.2 6,-0.2 74,-0.0 -0.990 13.7-157.7-150.1 145.9 41.3 -17.4 -16.5 5 56 A P - 0 0 41 0, 0.0 -1,-0.1 0, 0.0 73,-0.1 0.577 53.9 -61.6 -90.8-127.7 37.8 -16.6 -14.9 6 57 A R S S+ 0 0 198 1,-0.1 72,-0.0 74,-0.0 74,-0.0 0.423 131.6 54.2 -97.7 -20.4 34.1 -17.7 -15.6 7 58 A S S S- 0 0 96 2,-0.1 3,-0.1 0, 0.0 -1,-0.1 0.487 112.5-118.5 -92.1 -15.6 34.1 -16.1 -19.1 8 59 A G + 0 0 51 1,-0.3 2,-0.1 0, 0.0 -2,-0.0 0.414 57.1 160.3 85.2 1.9 37.2 -18.1 -20.1 9 60 A R - 0 0 97 1,-0.1 2,-0.3 21,-0.0 -1,-0.3 -0.326 30.0-142.7 -55.9 122.6 39.1 -14.8 -20.6 10 61 A T - 0 0 41 -6,-0.2 21,-2.5 -3,-0.1 22,-0.5 -0.722 17.6-169.0 -98.7 152.4 42.9 -15.6 -20.5 11 62 A Y E -AB 3 30A 12 -8,-2.1 -8,-2.6 -2,-0.3 2,-0.5 -0.995 20.7-132.5-136.0 130.3 45.7 -13.6 -19.0 12 63 A L E -AB 2 29A 91 17,-3.2 17,-2.0 -2,-0.4 2,-0.5 -0.782 20.4-134.1 -87.1 123.1 49.4 -14.4 -19.6 13 64 A K E - B 0 28A 32 -12,-3.6 15,-0.2 -2,-0.5 3,-0.1 -0.710 28.3-174.2 -79.2 123.3 51.4 -14.4 -16.3 14 65 A G E - 0 0 36 13,-3.9 -1,-0.1 -2,-0.5 3,-0.1 0.150 45.2 -21.0 -89.1-147.4 54.6 -12.5 -16.9 15 66 A R E S- 0 0 162 1,-0.1 12,-1.7 11,-0.1 2,-0.5 -0.229 70.6-105.1 -63.1 145.1 57.6 -12.2 -14.5 16 67 A L E - B 0 26A 72 10,-0.2 10,-0.3 1,-0.2 -1,-0.1 -0.658 30.8-168.1 -72.0 120.1 57.1 -12.8 -10.7 17 68 A L E - 0 0 57 8,-2.5 2,-0.3 -2,-0.5 9,-0.2 0.772 58.7 -49.6 -82.6 -29.9 57.1 -9.3 -9.2 18 69 A G E - B 0 25A 30 7,-1.1 7,-2.8 2,-0.0 -1,-0.4 -0.924 42.1-142.5 168.6 170.4 57.4 -10.5 -5.6 19 70 A K + 0 0 125 -2,-0.3 4,-0.1 5,-0.2 -2,-0.0 0.244 25.0 153.2-119.3-121.3 56.0 -12.9 -2.9 20 71 A G > - 0 0 53 2,-0.1 3,-1.9 -2,-0.0 -2,-0.0 0.645 64.2 -21.0 82.2 122.7 55.7 -12.3 0.9 21 72 A G T 3 S- 0 0 89 1,-0.3 -2,-0.0 3,-0.0 3,-0.0 0.017 127.1 -14.2 -34.0 109.2 53.1 -14.1 3.1 22 73 A F T 3 S+ 0 0 79 19,-0.1 2,-0.3 21,-0.0 -1,-0.3 -0.613 110.5 66.1-139.7 54.5 50.9 -15.2 1.5 23 74 A A < - 0 0 15 -3,-1.9 2,-0.5 19,-0.2 19,-0.2 -0.972 50.3-143.3-131.9 146.3 50.5 -14.0 -2.1 24 75 A R E - C 0 41A 89 17,-2.2 17,-3.1 -2,-0.3 2,-0.4 -0.923 22.5-152.6-107.5 127.7 52.5 -14.3 -5.4 25 76 A C E +BC 18 40A 30 -7,-2.8 -8,-2.5 -2,-0.5 -7,-1.1 -0.880 17.5 172.3-108.9 137.7 52.4 -11.3 -7.6 26 77 A Y E -BC 16 39A 31 13,-1.9 13,-3.4 -2,-0.4 2,-0.4 -0.969 39.8-111.1-138.0 155.4 52.8 -11.2 -11.4 27 78 A E E - C 0 38A 62 -12,-1.7 -13,-3.9 -2,-0.3 2,-0.4 -0.697 44.3-165.8 -78.2 134.1 52.6 -8.9 -14.3 28 79 A A E -BC 13 37A 0 9,-2.7 9,-1.7 -2,-0.4 2,-0.5 -0.981 10.3-164.9-134.0 123.2 49.5 -10.2 -16.2 29 80 A T E -BC 12 36A 40 -17,-2.0 -17,-3.2 -2,-0.4 7,-0.2 -0.924 27.1-117.9-111.4 129.0 48.5 -9.3 -19.7 30 81 A D E > -B 11 0A 4 5,-2.7 4,-1.8 -2,-0.5 -19,-0.3 -0.411 21.4-140.2 -59.8 127.2 45.1 -10.0 -21.2 31 82 A T T 4 S+ 0 0 68 -21,-2.5 -1,-0.1 1,-0.2 -20,-0.1 0.794 97.4 38.0 -62.5 -31.7 45.6 -12.4 -24.1 32 83 A E T 4 S+ 0 0 152 -22,-0.5 -1,-0.2 1,-0.1 -21,-0.1 0.771 131.5 21.9 -94.9 -28.5 43.0 -10.7 -26.3 33 84 A T T 4 S- 0 0 78 2,-0.1 -2,-0.2 0, 0.0 3,-0.1 0.582 90.4-128.7-111.7 -22.7 43.5 -6.9 -25.5 34 85 A G < + 0 0 46 -4,-1.8 -3,-0.1 1,-0.3 -23,-0.0 0.391 47.7 162.8 83.4 -2.0 47.1 -6.9 -24.1 35 86 A S - 0 0 49 -6,-0.1 -5,-2.7 1,-0.1 2,-0.3 -0.309 29.7-141.0 -55.6 122.6 45.9 -4.9 -21.0 36 87 A A E +C 29 0A 46 -7,-0.2 54,-0.4 -3,-0.1 2,-0.3 -0.720 25.8 170.3 -93.9 141.1 48.6 -5.2 -18.3 37 88 A Y E -C 28 0A 44 -9,-1.7 -9,-2.7 -2,-0.3 2,-0.6 -0.910 38.8-120.8-140.7 162.3 47.9 -5.7 -14.6 38 89 A A E -CD 27 88A 19 50,-2.8 50,-2.6 -2,-0.3 2,-0.5 -0.981 41.0-157.4-105.0 110.6 49.7 -6.5 -11.4 39 90 A V E -CD 26 87A 0 -13,-3.4 -13,-1.9 -2,-0.6 2,-0.7 -0.895 13.2-153.6-101.5 124.8 48.0 -9.7 -10.3 40 91 A K E -CD 25 86A 28 46,-3.1 46,-2.9 -2,-0.5 2,-0.7 -0.872 11.7-159.5 -95.7 117.9 48.0 -10.9 -6.7 41 92 A V E -CD 24 85A 13 -17,-3.1 -17,-2.2 -2,-0.7 44,-0.2 -0.901 11.3-175.3-102.8 104.7 47.5 -14.7 -6.7 42 93 A I E - D 0 84A 3 42,-3.4 42,-2.7 -2,-0.7 -19,-0.2 -0.935 24.3-128.5-105.1 117.4 46.2 -15.8 -3.3 43 94 A P E > - D 0 83A 26 0, 0.0 3,-0.8 0, 0.0 4,-0.4 -0.429 12.6-136.7 -65.7 132.0 45.9 -19.6 -2.7 44 95 A Q G > S+ 0 0 58 38,-3.4 3,-1.0 1,-0.2 39,-0.1 0.807 103.9 60.4 -55.2 -36.9 42.3 -20.4 -1.4 45 96 A S G > S+ 0 0 96 37,-0.5 3,-0.8 1,-0.2 4,-0.3 0.797 99.7 54.5 -62.6 -33.0 43.9 -22.8 1.2 46 97 A R G < S+ 0 0 99 -3,-0.8 -1,-0.2 1,-0.2 -2,-0.2 0.564 117.4 36.9 -78.2 -12.3 45.9 -19.9 2.8 47 98 A V G < S+ 0 0 2 -3,-1.0 -1,-0.2 -4,-0.4 -2,-0.2 0.022 83.8 107.6-126.4 21.0 42.7 -17.9 3.3 48 99 A A < + 0 0 74 -3,-0.8 -2,-0.1 4,-0.1 -3,-0.1 0.846 61.4 83.3 -69.0 -37.3 40.4 -20.9 4.2 49 100 A K S > S- 0 0 120 -4,-0.3 4,-2.4 1,-0.1 5,-0.2 -0.371 91.6-115.4 -69.3 145.5 40.2 -19.8 7.9 50 101 A P H > S+ 0 0 73 0, 0.0 4,-3.2 0, 0.0 5,-0.2 0.879 112.7 48.0 -49.5 -50.8 37.5 -17.1 8.8 51 102 A H H > S+ 0 0 99 1,-0.2 4,-1.8 2,-0.2 5,-0.1 0.883 116.4 44.0 -57.2 -43.6 40.0 -14.4 9.9 52 103 A Q H > S+ 0 0 42 2,-0.2 4,-1.7 -3,-0.2 -1,-0.2 0.816 114.9 49.3 -71.5 -34.4 42.1 -14.9 6.8 53 104 A R H X S+ 0 0 106 -4,-2.4 4,-2.3 2,-0.2 -2,-0.2 0.944 111.8 49.0 -68.4 -46.7 39.0 -15.0 4.5 54 105 A E H X S+ 0 0 111 -4,-3.2 4,-2.3 1,-0.2 -2,-0.2 0.833 109.1 53.1 -61.1 -38.3 37.6 -11.8 6.2 55 106 A K H X S+ 0 0 95 -4,-1.8 4,-2.0 2,-0.2 -1,-0.2 0.947 112.1 44.4 -62.5 -51.3 41.0 -10.0 5.6 56 107 A I H X S+ 0 0 14 -4,-1.7 4,-1.8 1,-0.2 -2,-0.2 0.874 115.0 47.9 -62.4 -40.3 41.0 -10.9 1.9 57 108 A L H X S+ 0 0 84 -4,-2.3 4,-3.1 1,-0.2 -1,-0.2 0.889 110.7 51.9 -69.6 -39.5 37.3 -9.9 1.4 58 109 A N H X S+ 0 0 40 -4,-2.3 4,-3.1 2,-0.2 5,-0.3 0.877 107.0 52.8 -61.9 -44.5 37.8 -6.6 3.2 59 110 A E H X S+ 0 0 5 -4,-2.0 4,-2.8 2,-0.2 5,-0.2 0.954 114.0 42.9 -55.3 -52.3 40.8 -5.7 1.0 60 111 A I H X S+ 0 0 7 -4,-1.8 4,-2.6 1,-0.2 -2,-0.2 0.936 115.2 50.7 -60.2 -46.9 38.6 -6.3 -2.1 61 112 A E H < S+ 0 0 101 -4,-3.1 4,-0.4 1,-0.2 -2,-0.2 0.866 117.9 36.3 -58.8 -48.3 35.6 -4.5 -0.5 62 113 A L H < S+ 0 0 9 -4,-3.1 4,-0.2 1,-0.1 -1,-0.2 0.839 119.7 48.1 -77.4 -36.2 37.5 -1.4 0.5 63 114 A H H >< S+ 0 0 0 -4,-2.8 3,-1.5 -5,-0.3 11,-0.5 0.853 91.4 84.5 -72.2 -35.7 39.8 -1.3 -2.6 64 115 A R T 3< S+ 0 0 122 -4,-2.6 10,-0.2 1,-0.3 -1,-0.2 0.760 100.9 25.2 -29.7 -68.7 36.9 -1.8 -5.2 65 116 A D T 3 S+ 0 0 78 -4,-0.4 2,-0.5 -3,-0.2 -1,-0.3 0.294 83.2 130.9 -91.3 3.4 35.7 1.8 -5.7 66 117 A L < + 0 0 0 -3,-1.5 2,-0.5 -4,-0.2 8,-0.4 -0.509 29.1 174.8 -66.2 106.7 38.9 3.8 -4.8 67 118 A Q + 0 0 132 -2,-0.5 2,-0.3 6,-0.1 5,-0.1 -0.859 23.0 120.7-124.2 95.0 39.4 6.3 -7.6 68 119 A H > - 0 0 43 -2,-0.5 3,-2.2 3,-0.4 53,-0.0 -0.977 64.1-124.4-154.0 141.0 42.3 8.7 -7.0 69 120 A R T 3 S+ 0 0 139 -2,-0.3 4,-0.1 1,-0.3 52,-0.1 0.691 115.3 50.0 -61.9 -21.6 45.5 9.4 -9.0 70 121 A H T 3 S+ 0 0 11 79,-0.1 80,-3.1 2,-0.1 2,-0.4 0.176 102.0 78.7-104.0 18.7 47.5 8.7 -5.8 71 122 A I B < S-f 150 0B 2 -3,-2.2 -3,-0.4 78,-0.3 80,-0.2 -0.993 88.4-109.3-129.3 131.5 45.7 5.4 -5.2 72 123 A V - 0 0 6 78,-2.8 2,-0.6 -2,-0.4 -6,-0.1 -0.318 38.1-121.9 -54.4 128.7 46.3 2.1 -6.9 73 124 A R - 0 0 90 -4,-0.1 16,-1.8 -6,-0.1 2,-0.3 -0.727 16.2-141.8 -82.4 119.9 43.4 1.3 -9.1 74 125 A F E -E 88 0A 8 -2,-0.6 14,-0.2 -11,-0.5 3,-0.1 -0.658 21.2-176.7 -71.7 130.0 41.7 -2.0 -8.2 75 126 A S E - 0 0 51 12,-3.1 2,-0.3 1,-0.4 13,-0.2 0.872 46.9 -56.1 -96.2 -64.9 40.7 -3.5 -11.6 76 127 A H E -E 87 0A 46 11,-0.9 11,-3.2 2,-0.0 -1,-0.4 -0.963 41.9-145.1-168.5 166.7 38.8 -6.7 -10.8 77 128 A H E +E 86 0A 36 -2,-0.3 2,-0.3 9,-0.2 9,-0.2 -0.911 14.2 173.8-137.5 164.7 39.1 -10.0 -9.0 78 129 A F E -E 85 0A 6 7,-1.5 7,-2.9 -2,-0.3 2,-0.3 -0.932 12.5-152.9-162.9 164.3 37.9 -13.6 -9.6 79 130 A E E -E 84 0A 73 -2,-0.3 5,-0.2 5,-0.2 2,-0.2 -0.991 12.2-174.8-151.0 150.2 38.4 -16.9 -7.9 80 131 A D - 0 0 58 3,-2.4 -36,-0.1 -2,-0.3 -74,-0.0 -0.659 55.9 -81.8-127.0-178.0 38.5 -20.6 -8.5 81 132 A A S S+ 0 0 94 -2,-0.2 3,-0.1 1,-0.2 -37,-0.1 0.717 128.3 41.3 -65.2 -20.4 38.9 -23.5 -6.0 82 133 A D S S+ 0 0 118 1,-0.2 -38,-3.4 -38,-0.1 -37,-0.5 0.903 119.1 13.1 -89.3 -54.9 42.8 -23.0 -6.0 83 134 A N E -D 43 0A 34 -40,-0.3 -3,-2.4 -39,-0.1 2,-0.5 -0.877 49.7-136.2-131.7 164.4 43.3 -19.2 -6.1 84 135 A I E -DE 42 79A 8 -42,-2.7 -42,-3.4 -2,-0.3 2,-0.6 -0.961 27.8-156.6-109.6 123.2 42.0 -15.7 -5.7 85 136 A Y E -DE 41 78A 19 -7,-2.9 -7,-1.5 -2,-0.5 2,-0.6 -0.950 7.6-169.9-107.3 112.4 43.3 -13.5 -8.5 86 137 A I E -DE 40 77A 0 -46,-2.9 -46,-3.1 -2,-0.6 2,-0.5 -0.944 8.8-154.6-107.2 116.3 43.3 -9.8 -7.6 87 138 A F E +DE 39 76A 0 -11,-3.2 -12,-3.1 -2,-0.6 -11,-0.9 -0.809 22.8 169.4 -97.6 121.2 44.0 -7.5 -10.6 88 139 A L E -DE 38 74A 16 -50,-2.6 -50,-2.8 -2,-0.5 -14,-0.2 -0.850 43.4 -72.0-127.9 161.6 45.5 -4.2 -9.8 89 140 A E - 0 0 60 -16,-1.8 2,-0.4 -2,-0.3 -52,-0.1 -0.324 48.2-132.1 -54.1 121.6 47.1 -1.2 -11.5 90 141 A L - 0 0 47 -54,-0.4 2,-0.6 -2,-0.1 -1,-0.1 -0.714 16.5-161.9 -81.9 131.6 50.5 -2.2 -12.7 91 142 A C > - 0 0 14 -2,-0.4 3,-1.4 52,-0.1 51,-0.3 -0.972 5.6-156.9-118.4 103.0 53.1 0.4 -11.7 92 143 A S T 3 S+ 0 0 54 -2,-0.6 51,-0.2 1,-0.3 -1,-0.1 0.645 87.7 60.1 -56.0 -21.9 56.2 -0.1 -14.0 93 144 A R T 3 S- 0 0 82 49,-2.1 -1,-0.3 1,-0.3 50,-0.2 0.099 98.7-138.9-100.8 27.0 58.6 1.6 -11.6 94 145 A K < - 0 0 123 -3,-1.4 48,-3.0 48,-0.2 -1,-0.3 -0.357 42.3 -43.8 59.1-129.0 57.9 -0.9 -8.7 95 146 A S B > -G 141 0B 1 46,-0.3 4,-2.2 -3,-0.1 46,-0.2 -0.803 46.3-104.4-130.6 169.0 57.6 0.6 -5.2 96 147 A L H > S+ 0 0 0 44,-1.9 4,-2.9 41,-1.1 42,-0.3 0.754 122.0 60.7 -65.4 -20.4 59.4 3.1 -2.9 97 148 A A H > S+ 0 0 14 40,-1.1 4,-2.4 2,-0.2 -1,-0.2 0.924 105.7 46.4 -70.8 -42.7 60.8 0.1 -1.1 98 149 A H H > S+ 0 0 71 2,-0.2 4,-1.6 39,-0.2 -2,-0.2 0.906 115.7 44.7 -63.4 -45.6 62.5 -1.0 -4.4 99 150 A I H X S+ 0 0 3 -4,-2.2 4,-3.1 1,-0.2 5,-0.3 0.936 113.0 51.8 -65.4 -43.4 63.8 2.6 -4.9 100 151 A W H X S+ 0 0 70 -4,-2.9 4,-3.2 1,-0.2 -2,-0.2 0.881 107.3 52.5 -59.5 -38.5 64.8 2.8 -1.2 101 152 A K H < S+ 0 0 128 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.877 116.7 40.1 -64.4 -36.7 66.8 -0.6 -1.6 102 153 A A H < S+ 0 0 55 -4,-1.6 -2,-0.2 175,-0.3 -1,-0.2 0.846 131.8 24.8 -76.8 -40.2 68.6 1.0 -4.7 103 154 A R H < S- 0 0 26 -4,-3.1 2,-2.0 174,-0.2 -3,-0.2 0.765 73.6-161.0 -97.3 -38.9 69.1 4.5 -3.2 104 155 A H S < S+ 0 0 101 -4,-3.2 2,-0.3 -5,-0.3 -1,-0.1 -0.282 78.9 31.2 75.8 -48.6 69.0 4.1 0.7 105 156 A T S S- 0 0 54 -2,-2.0 2,-0.3 99,-0.1 98,-0.2 -0.961 71.5-149.0-131.9 157.4 68.3 7.8 0.9 106 157 A L - 0 0 6 96,-2.8 174,-0.1 -2,-0.3 2,-0.0 -0.888 30.1-104.6-119.2 152.3 66.4 10.3 -1.2 107 158 A L >> - 0 0 82 -2,-0.3 4,-2.2 1,-0.1 3,-0.7 -0.330 38.2-103.6 -74.0 155.4 67.2 14.0 -1.5 108 159 A E H 3> S+ 0 0 42 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.877 121.3 51.0 -50.1 -44.4 64.9 16.4 0.3 109 160 A P H 3> S+ 0 0 39 0, 0.0 4,-2.3 0, 0.0 -1,-0.2 0.820 111.5 50.1 -63.6 -30.9 63.0 17.6 -2.9 110 161 A E H <> S+ 0 0 2 -3,-0.7 4,-2.4 2,-0.2 -2,-0.2 0.890 111.2 47.0 -67.7 -47.7 62.4 13.8 -3.7 111 162 A V H X S+ 0 0 0 -4,-2.2 4,-3.4 2,-0.2 5,-0.2 0.945 115.3 46.4 -59.5 -49.8 61.1 13.1 -0.2 112 163 A R H X S+ 0 0 11 -4,-2.7 4,-2.2 1,-0.2 -2,-0.2 0.896 111.4 53.0 -58.8 -43.8 58.9 16.2 -0.5 113 164 A Y H X S+ 0 0 17 -4,-2.3 4,-0.9 2,-0.2 -1,-0.2 0.855 117.2 36.8 -57.5 -44.5 57.8 15.1 -4.1 114 165 A Y H X S+ 0 0 0 -4,-2.4 4,-2.5 2,-0.2 3,-0.2 0.919 112.4 57.3 -80.0 -42.1 56.7 11.7 -2.8 115 166 A L H X S+ 0 0 6 -4,-3.4 4,-3.0 1,-0.2 5,-0.2 0.866 104.2 54.3 -53.6 -43.7 55.3 12.8 0.6 116 167 A R H X S+ 0 0 84 -4,-2.2 4,-2.4 2,-0.2 -1,-0.2 0.917 112.1 43.8 -55.4 -47.7 52.9 15.2 -1.3 117 168 A Q H X S+ 0 0 17 -4,-0.9 4,-2.7 2,-0.2 -2,-0.2 0.896 114.1 48.9 -65.4 -45.2 51.6 12.3 -3.4 118 169 A I H X S+ 0 0 0 -4,-2.5 4,-3.2 2,-0.2 -2,-0.2 0.928 113.9 47.6 -58.5 -49.9 51.3 9.9 -0.4 119 170 A L H X S+ 0 0 3 -4,-3.0 4,-2.5 2,-0.2 -2,-0.2 0.845 111.2 50.3 -62.6 -37.8 49.5 12.8 1.6 120 171 A S H X S+ 0 0 22 -4,-2.4 4,-2.0 2,-0.2 -2,-0.2 0.956 114.3 45.6 -64.3 -46.2 47.1 13.4 -1.4 121 172 A G H X S+ 0 0 0 -4,-2.7 4,-1.9 1,-0.2 -2,-0.2 0.933 115.0 45.9 -59.6 -53.9 46.4 9.6 -1.5 122 173 A L H X S+ 0 0 0 -4,-3.2 4,-3.3 2,-0.2 -1,-0.2 0.883 108.8 55.6 -58.2 -46.7 45.9 9.3 2.2 123 174 A K H X S+ 0 0 76 -4,-2.5 4,-2.8 2,-0.2 -1,-0.2 0.928 108.1 49.7 -51.2 -48.9 43.7 12.4 2.4 124 175 A Y H X S+ 0 0 33 -4,-2.0 4,-1.1 2,-0.2 -2,-0.2 0.912 113.5 46.4 -56.0 -45.9 41.4 10.7 -0.3 125 176 A L H ><>S+ 0 0 0 -4,-1.9 5,-2.2 1,-0.2 3,-0.8 0.938 113.5 47.7 -62.3 -50.7 41.3 7.5 1.9 126 177 A H H ><5S+ 0 0 32 -4,-3.3 3,-1.6 1,-0.3 -2,-0.2 0.856 108.6 54.3 -60.4 -39.1 40.6 9.4 5.1 127 178 A Q H 3<5S+ 0 0 137 -4,-2.8 -1,-0.3 1,-0.3 -2,-0.2 0.739 107.4 51.9 -66.6 -24.9 37.8 11.5 3.4 128 179 A R T <<5S- 0 0 124 -4,-1.1 -1,-0.3 -3,-0.8 -2,-0.2 0.275 121.5-111.3 -93.3 7.9 36.3 8.1 2.4 129 180 A G T < 5S+ 0 0 30 -3,-1.6 30,-3.3 1,-0.2 2,-0.4 0.791 77.0 129.3 64.4 31.7 36.5 6.9 6.1 130 181 A I E < -I 158 0C 11 -5,-2.2 2,-0.4 28,-0.3 -1,-0.2 -0.970 45.5-154.6-117.8 133.1 39.1 4.3 5.3 131 182 A L E -I 157 0C 2 26,-3.3 26,-2.2 -2,-0.4 55,-0.0 -0.862 7.9-151.1-102.7 136.7 42.4 4.0 7.2 132 183 A H - 0 0 0 -2,-0.4 23,-0.2 24,-0.2 -1,-0.2 0.976 17.8-175.3 -72.4 -51.6 45.3 2.4 5.4 133 184 A R + 0 0 32 54,-0.1 39,-0.1 23,-0.1 -1,-0.1 0.302 69.3 65.8 74.4 -5.6 47.0 1.0 8.6 134 185 A D + 0 0 18 37,-0.2 2,-0.6 18,-0.1 5,-0.1 -0.150 61.7 162.2-137.8 42.6 50.0 -0.3 6.6 135 186 A L + 0 0 0 40,-0.1 2,-0.3 3,-0.1 63,-0.1 -0.538 21.7 128.3 -71.9 114.1 51.8 2.8 5.3 136 187 A K S > S- 0 0 55 -2,-0.6 3,-2.0 61,-0.1 -40,-0.1 -0.944 72.6 -95.9-157.8 162.1 55.3 1.9 4.4 137 188 A L G > S+ 0 0 4 -2,-0.3 3,-1.8 1,-0.3 -41,-1.1 0.820 119.9 64.1 -50.8 -41.4 57.7 2.3 1.3 138 189 A G G 3 S+ 0 0 25 1,-0.3 -1,-0.3 -42,-0.3 -40,-0.1 0.644 102.3 51.0 -57.8 -20.6 56.7 -1.2 0.2 139 190 A N G < S+ 0 0 7 -3,-2.0 12,-3.4 -5,-0.1 2,-0.7 0.226 86.3 91.2-106.2 8.8 53.1 0.0 -0.3 140 191 A F E < - H 0 150B 0 -3,-1.8 -44,-1.9 10,-0.2 2,-0.3 -0.895 66.3-155.3-112.7 99.5 53.9 3.1 -2.4 141 192 A F E -GH 95 149B 55 8,-3.2 8,-2.9 -2,-0.7 2,-0.5 -0.592 0.2-148.7 -83.4 134.3 53.7 2.1 -6.1 142 193 A I E - H 0 148B 0 -48,-3.0 -49,-2.1 -51,-0.3 6,-0.2 -0.923 8.5-156.0-111.2 126.8 55.6 4.1 -8.8 143 194 A T > - 0 0 13 4,-2.0 3,-2.0 -2,-0.5 -52,-0.1 -0.370 39.2 -95.4 -86.1 177.1 54.4 4.4 -12.3 144 195 A E T 3 S+ 0 0 77 1,-0.3 130,-0.1 2,-0.2 -53,-0.1 0.770 127.7 57.0 -60.0 -32.0 56.4 5.1 -15.5 145 196 A N T 3 S- 0 0 84 2,-0.1 -1,-0.3 128,-0.0 127,-0.3 0.315 121.2-110.5 -82.3 2.3 55.5 8.8 -15.0 146 197 A M < + 0 0 1 -3,-2.0 2,-0.5 1,-0.3 126,-0.2 0.898 68.5 152.9 65.9 37.8 57.1 8.7 -11.5 147 198 A E - 0 0 57 124,-0.1 -4,-2.0 -4,-0.0 2,-0.4 -0.901 41.7-131.9-101.5 130.9 53.6 9.0 -10.0 148 199 A L E - H 0 142B 0 -2,-0.5 2,-0.5 -6,-0.2 -6,-0.2 -0.705 19.9-170.7 -90.0 133.3 53.1 7.5 -6.6 149 200 A K E - H 0 141B 13 -8,-2.9 -8,-3.2 -2,-0.4 2,-0.4 -0.991 22.2-132.5-121.2 120.9 50.0 5.3 -6.1 150 201 A V E +fH 71 140B 0 -80,-3.1 -78,-2.8 -2,-0.5 -10,-0.2 -0.616 41.8 172.5 -75.6 127.4 49.3 4.2 -2.5 151 202 A G + 0 0 0 -12,-3.4 -12,-0.1 -2,-0.4 -1,-0.0 -0.697 29.3 66.0-126.6-175.1 48.6 0.5 -2.6 152 203 A D - 0 0 51 -2,-0.2 3,-0.5 1,-0.1 -1,-0.1 0.999 36.2-175.6 59.0 88.7 48.0 -2.7 -0.6 153 204 A F > + 0 0 0 1,-0.2 3,-1.0 2,-0.1 -91,-0.1 0.123 48.6 118.9 -95.3 20.8 44.7 -2.5 1.2 154 205 A G T 3 S+ 0 0 3 1,-0.3 -1,-0.2 -20,-0.1 -95,-0.2 0.768 89.5 28.3 -57.8 -31.1 45.4 -5.8 3.0 155 206 A L T 3 S+ 0 0 35 -3,-0.5 -1,-0.3 -23,-0.2 -2,-0.1 0.292 92.1 132.7-114.1 7.0 45.2 -4.0 6.4 156 207 A A < - 0 0 2 -3,-1.0 2,-0.3 -22,-0.1 -24,-0.2 -0.211 34.2-175.3 -61.0 146.6 42.8 -1.2 5.3 157 208 A A E -I 131 0C 20 -26,-2.2 -26,-3.3 -95,-0.1 2,-0.2 -0.992 33.9 -97.0-143.7 156.3 39.9 -0.6 7.7 158 209 A R E -I 130 0C 134 -2,-0.3 2,-0.4 -28,-0.2 -28,-0.3 -0.530 50.4-112.5 -71.7 127.4 36.7 1.5 8.1 159 210 A L - 0 0 62 -30,-3.3 28,-0.1 -2,-0.2 -1,-0.1 -0.576 46.8-178.0 -66.9 121.0 37.7 4.5 10.3 160 211 A E - 0 0 68 26,-0.4 5,-0.1 -2,-0.4 -31,-0.0 -0.913 32.5 -92.0-121.0 153.3 35.8 3.9 13.5 161 212 A P > - 0 0 73 0, 0.0 4,-2.9 0, 0.0 3,-0.3 -0.167 47.8-101.5 -57.5 156.9 35.5 6.0 16.8 162 213 A P T 4 S+ 0 0 75 0, 0.0 -2,-0.0 0, 0.0 24,-0.0 0.818 121.6 46.2 -47.9 -43.7 38.1 5.2 19.5 163 214 A E T 4 S+ 0 0 175 1,-0.2 -3,-0.0 0, 0.0 0, 0.0 0.858 119.1 41.7 -70.5 -34.8 35.7 3.1 21.7 164 215 A Q T 4 S+ 0 0 130 -3,-0.3 -1,-0.2 2,-0.1 3,-0.1 0.863 91.2 99.8 -79.4 -43.4 34.4 1.2 18.6 165 216 A R S < S- 0 0 30 -4,-2.9 -6,-0.1 1,-0.1 22,-0.0 -0.052 84.8 -97.9 -49.9 145.6 37.6 0.5 16.7 166 217 A K - 0 0 166 1,-0.1 20,-0.4 20,-0.1 -1,-0.1 -0.375 25.5-149.2 -62.9 142.1 39.4 -2.9 16.9 167 218 A K + 0 0 72 18,-0.2 18,-0.3 -3,-0.1 -1,-0.1 0.060 49.5 136.3-104.8 18.4 42.3 -2.7 19.4 168 219 A T - 0 0 67 16,-0.1 2,-0.7 1,-0.1 17,-0.1 -0.284 58.5-121.8 -66.7 145.6 44.3 -5.4 17.6 169 220 A I + 0 0 59 14,-0.1 2,-0.3 12,-0.1 12,-0.1 -0.876 54.9 137.5 -94.2 113.6 48.1 -4.8 17.1 170 221 A C + 0 0 25 -2,-0.7 2,-0.1 2,-0.1 -37,-0.0 -0.958 16.6 73.8-151.3 166.4 48.8 -4.9 13.3 171 222 A G S S- 0 0 18 -2,-0.3 -37,-0.2 5,-0.1 5,-0.1 -0.140 91.5 -43.7 105.6 157.4 50.8 -3.0 10.7 172 223 A T >> - 0 0 31 1,-0.1 3,-2.1 -39,-0.1 4,-1.3 -0.402 55.2-134.5 -58.9 119.0 54.5 -3.1 9.9 173 224 A P T 34 S+ 0 0 42 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.789 102.5 53.0 -46.0 -41.5 56.4 -2.8 13.3 174 225 A N T 34 S+ 0 0 35 1,-0.2 35,-0.4 34,-0.0 36,-0.1 0.694 118.7 37.5 -67.6 -20.9 58.9 -0.2 12.2 175 226 A Y T <4 S+ 0 0 22 -3,-2.1 22,-0.2 32,-0.1 -1,-0.2 0.527 88.5 119.8-107.2 -13.3 56.0 2.1 11.0 176 227 A V < - 0 0 4 -4,-1.3 -5,-0.1 -3,-0.2 15,-0.1 -0.369 62.0-122.7 -66.0 130.4 53.4 1.3 13.7 177 228 A A >> - 0 0 0 -2,-0.2 4,-1.6 13,-0.1 3,-1.0 -0.284 21.3-116.8 -67.7 147.7 52.1 4.2 15.9 178 229 A P H 3> S+ 0 0 1 0, 0.0 4,-1.9 0, 0.0 5,-0.1 0.862 114.0 57.9 -59.3 -36.1 52.5 4.0 19.8 179 230 A E H 34>S+ 0 0 11 67,-0.3 5,-2.8 2,-0.2 6,-0.4 0.760 104.9 53.1 -64.3 -26.2 48.6 4.0 20.4 180 231 A V H X45S+ 0 0 0 -3,-1.0 3,-1.7 4,-0.2 5,-0.4 0.939 109.5 46.4 -74.1 -45.3 48.5 0.8 18.2 181 232 A L H 3<5S+ 0 0 7 -4,-1.6 -2,-0.2 1,-0.3 -1,-0.2 0.827 108.9 57.8 -62.1 -29.8 51.2 -0.9 20.3 182 233 A L T 3<5S- 0 0 95 -4,-1.9 -1,-0.3 -5,-0.2 -2,-0.2 0.265 119.7-113.6 -84.6 10.6 49.1 0.3 23.4 183 234 A R T < 5S+ 0 0 157 -3,-1.7 -3,-0.2 -5,-0.1 -2,-0.1 0.851 83.8 123.1 57.4 40.0 46.1 -1.6 22.0 184 235 A Q < - 0 0 108 -5,-2.8 -4,-0.2 1,-0.3 -16,-0.1 0.371 68.8-131.1-101.6 -1.6 44.1 1.6 21.3 185 236 A G - 0 0 0 -6,-0.4 2,-0.4 -5,-0.4 -1,-0.3 -0.145 34.1 -50.2 78.4-176.9 43.7 0.6 17.7 186 237 A H + 0 0 8 -20,-0.4 -26,-0.4 -6,-0.1 -20,-0.1 -0.828 51.4 171.7 -99.7 128.9 44.4 2.7 14.5 187 238 A G >> - 0 0 0 -2,-0.4 3,-1.0 -28,-0.1 4,-0.9 -0.633 56.6 -89.1-116.4 178.5 42.9 6.2 14.0 188 239 A P H 3> S+ 0 0 32 0, 0.0 4,-1.8 0, 0.0 3,-0.1 0.811 128.4 64.6 -60.0 -27.0 43.8 8.6 11.1 189 240 A E H 3> S+ 0 0 62 1,-0.2 4,-2.4 2,-0.2 5,-0.1 0.817 94.9 57.9 -64.2 -32.2 46.6 9.8 13.5 190 241 A A H <> S+ 0 0 0 -3,-1.0 4,-2.2 2,-0.2 -1,-0.2 0.876 105.7 48.9 -67.1 -37.2 48.3 6.3 13.3 191 242 A D H X S+ 0 0 0 -4,-0.9 4,-1.7 2,-0.2 -2,-0.2 0.920 110.6 51.2 -65.6 -43.3 48.5 6.6 9.4 192 243 A V H X S+ 0 0 6 -4,-1.8 4,-1.8 1,-0.2 -2,-0.2 0.922 109.0 50.9 -57.9 -46.6 50.0 10.1 10.0 193 244 A W H X S+ 0 0 0 -4,-2.4 4,-2.0 1,-0.2 3,-0.2 0.917 107.2 53.1 -56.6 -48.0 52.6 8.6 12.4 194 245 A S H X S+ 0 0 4 -4,-2.2 4,-2.0 1,-0.2 -1,-0.2 0.842 107.6 52.8 -57.7 -34.6 53.5 5.9 9.8 195 246 A L H X S+ 0 0 3 -4,-1.7 4,-3.2 2,-0.2 -1,-0.2 0.847 103.6 55.3 -68.1 -38.5 54.1 8.8 7.3 196 247 A G H X S+ 0 0 0 -4,-1.8 4,-2.5 -3,-0.2 -2,-0.2 0.928 110.2 47.3 -58.5 -39.5 56.5 10.4 9.8 197 248 A C H X S+ 0 0 0 -4,-2.0 4,-2.8 -22,-0.2 -2,-0.2 0.908 110.8 51.1 -68.6 -38.4 58.3 7.1 9.7 198 249 A V H X S+ 0 0 0 -4,-2.0 4,-2.1 2,-0.2 -2,-0.2 0.928 111.2 47.9 -60.8 -52.1 58.2 7.0 5.9 199 250 A M H X S+ 0 0 2 -4,-3.2 4,-2.0 1,-0.2 -2,-0.2 0.923 113.7 47.0 -54.0 -50.8 59.6 10.6 5.8 200 251 A Y H X S+ 0 0 19 -4,-2.5 4,-3.0 1,-0.2 5,-0.5 0.897 111.4 50.7 -59.6 -46.5 62.4 9.7 8.3 201 252 A T H X S+ 0 0 0 -4,-2.8 4,-1.7 1,-0.2 -1,-0.2 0.857 112.1 47.7 -60.6 -40.5 63.3 6.4 6.5 202 253 A L H < S+ 0 0 2 -4,-2.1 -96,-2.8 2,-0.2 -1,-0.2 0.834 118.8 39.3 -69.8 -38.7 63.6 8.2 3.1 203 254 A L H < S+ 0 0 16 -4,-2.0 -2,-0.2 -98,-0.2 -3,-0.2 0.899 128.8 27.9 -79.2 -41.0 65.7 11.1 4.5 204 255 A C H < S- 0 0 31 -4,-3.0 -3,-0.2 2,-0.2 -2,-0.2 0.733 102.5-115.4 -96.4 -28.9 68.0 9.1 6.9 205 256 A G S < S+ 0 0 0 -4,-1.7 -4,-0.2 -5,-0.5 -3,-0.1 0.094 86.4 52.0 113.8 -22.5 68.1 5.6 5.3 206 257 A S S S- 0 0 44 -6,-0.3 -2,-0.2 4,-0.0 -1,-0.2 -0.965 94.5 -83.4-143.0 156.6 66.4 3.5 8.0 207 258 A P > - 0 0 9 0, 0.0 3,-1.4 0, 0.0 -32,-0.1 -0.297 46.0-117.6 -59.0 145.6 63.1 3.6 10.0 208 259 A P T 3 S+ 0 0 12 0, 0.0 19,-0.4 0, 0.0 -33,-0.1 0.788 109.5 37.5 -60.3 -30.8 63.4 5.9 13.0 209 260 A F T 3 S+ 0 0 2 -35,-0.4 11,-0.2 17,-0.1 12,-0.2 0.161 81.9 140.0-109.1 20.2 62.9 3.2 15.7 210 261 A E < + 0 0 99 -3,-1.4 2,-0.2 -36,-0.1 4,-0.1 -0.390 20.4 152.4 -67.5 132.0 64.8 0.4 14.0 211 262 A T - 0 0 52 2,-0.2 6,-0.1 -2,-0.1 -2,-0.1 -0.827 60.6 -90.6-145.3 179.7 66.9 -1.6 16.5 212 263 A A S S+ 0 0 103 -2,-0.2 2,-0.3 2,-0.0 -2,-0.0 0.790 108.7 48.1 -68.6 -31.4 68.2 -5.3 16.7 213 264 A D S > S- 0 0 109 1,-0.1 4,-1.6 -3,-0.0 -2,-0.2 -0.837 70.8-139.2-117.4 152.6 65.0 -6.4 18.5 214 265 A L H > S+ 0 0 87 -2,-0.3 4,-2.6 2,-0.2 5,-0.1 0.888 108.0 54.6 -71.6 -41.8 61.2 -5.9 18.0 215 266 A K H > S+ 0 0 136 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.900 109.5 47.0 -58.9 -45.1 60.8 -5.4 21.8 216 267 A E H > S+ 0 0 79 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.878 111.1 51.2 -66.7 -39.7 63.4 -2.6 21.8 217 268 A T H X S+ 0 0 5 -4,-1.6 4,-2.7 2,-0.2 -2,-0.2 0.942 109.8 50.2 -60.0 -49.4 61.8 -0.9 18.7 218 269 A Y H X S+ 0 0 40 -4,-2.6 4,-2.5 1,-0.2 -2,-0.2 0.877 111.7 48.2 -57.8 -40.8 58.4 -1.0 20.5 219 270 A R H X S+ 0 0 130 -4,-2.0 4,-1.8 2,-0.2 -1,-0.2 0.837 112.1 49.4 -66.7 -39.4 60.0 0.6 23.6 220 271 A C H <>S+ 0 0 10 -4,-2.1 5,-3.4 -11,-0.2 4,-0.5 0.874 112.4 48.1 -69.0 -35.4 61.6 3.2 21.4 221 272 A I H ><5S+ 0 0 0 -4,-2.7 3,-0.7 3,-0.2 -2,-0.2 0.936 111.5 49.2 -65.8 -52.5 58.2 3.9 19.6 222 273 A K H 3<5S+ 0 0 95 -4,-2.5 -2,-0.2 1,-0.3 -1,-0.2 0.857 120.4 36.6 -58.5 -38.5 56.3 4.2 23.0 223 274 A Q T 3<5S- 0 0 161 -4,-1.8 -1,-0.3 -5,-0.2 -2,-0.2 0.497 107.8-126.5 -93.4 -1.4 58.9 6.6 24.4 224 275 A V T < 5 + 0 0 33 -3,-0.7 2,-0.7 -4,-0.5 -3,-0.2 0.974 48.0 169.5 49.9 54.2 59.4 8.3 20.9 225 276 A H < + 0 0 126 -5,-3.4 2,-0.3 -8,-0.2 -1,-0.2 -0.920 15.3 124.2-101.7 105.8 63.1 7.6 21.2 226 277 A Y - 0 0 43 -2,-0.7 2,-0.4 -3,-0.1 -17,-0.1 -0.953 54.2-116.2-158.3 156.3 64.9 8.3 17.9 227 278 A T - 0 0 103 -19,-0.4 -2,-0.0 -2,-0.3 0, 0.0 -0.838 14.3-145.8-103.2 134.7 67.8 10.5 16.7 228 279 A L - 0 0 51 -2,-0.4 9,-0.0 4,-0.0 -2,-0.0 -0.900 27.4-125.2 -98.5 109.3 67.4 13.3 14.2 229 280 A P > - 0 0 40 0, 0.0 3,-1.4 0, 0.0 8,-0.1 -0.334 12.1-130.5 -56.6 137.2 70.6 13.5 12.1 230 281 A A T 3 S+ 0 0 95 1,-0.2 7,-0.1 7,-0.0 -2,-0.0 0.767 102.2 67.2 -57.9 -30.4 72.1 17.0 12.1 231 282 A S T 3 S+ 0 0 113 2,-0.0 -1,-0.2 3,-0.0 2,-0.1 0.638 77.7 96.6 -67.5 -22.0 72.4 17.0 8.3 232 283 A L S < S- 0 0 12 -3,-1.4 -4,-0.0 1,-0.1 5,-0.0 -0.467 87.5-100.6 -71.1 147.0 68.5 17.1 7.8 233 284 A S > - 0 0 34 -2,-0.1 4,-2.2 1,-0.1 5,-0.2 -0.173 27.6-111.9 -62.0 157.9 67.2 20.6 7.2 234 285 A L H > S+ 0 0 94 2,-0.2 4,-3.0 1,-0.2 5,-0.2 0.945 119.3 51.7 -59.4 -47.4 65.5 22.4 10.0 235 286 A P H > S+ 0 0 38 0, 0.0 4,-2.6 0, 0.0 27,-0.4 0.883 110.4 50.4 -58.4 -34.1 62.0 22.2 8.3 236 287 A A H > S+ 0 0 0 2,-0.2 4,-2.5 1,-0.2 -2,-0.2 0.938 114.2 42.6 -66.4 -46.2 62.5 18.4 7.9 237 288 A R H X S+ 0 0 75 -4,-2.2 4,-2.4 2,-0.2 -1,-0.2 0.872 114.9 51.6 -66.2 -39.6 63.4 17.9 11.6 238 289 A Q H X S+ 0 0 77 -4,-3.0 4,-2.1 2,-0.2 -2,-0.2 0.922 113.1 44.4 -63.2 -47.4 60.6 20.3 12.7 239 290 A L H X S+ 0 0 1 -4,-2.6 4,-2.5 -5,-0.2 -2,-0.2 0.894 113.1 50.4 -64.9 -41.9 58.0 18.3 10.6 240 291 A L H X S+ 0 0 0 -4,-2.5 4,-3.3 1,-0.2 -2,-0.2 0.924 112.3 48.5 -60.8 -43.1 59.4 14.9 11.9 241 292 A A H < S+ 0 0 46 -4,-2.4 -2,-0.2 2,-0.2 -1,-0.2 0.856 112.4 47.4 -63.9 -43.5 59.1 16.2 15.5 242 293 A A H < S+ 0 0 28 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.892 118.9 41.5 -66.3 -40.4 55.5 17.5 15.0 243 294 A I H < S+ 0 0 5 -4,-2.5 2,-2.0 1,-0.2 -2,-0.2 0.914 104.8 64.5 -72.9 -48.2 54.5 14.2 13.3 244 295 A L S < S+ 0 0 7 -4,-3.3 2,-0.4 -5,-0.2 -1,-0.2 -0.510 71.4 141.8 -83.0 70.0 56.4 11.8 15.7 245 296 A R - 0 0 108 -2,-2.0 6,-0.1 -3,-0.2 -21,-0.1 -0.952 53.2-138.8-112.3 131.6 54.3 12.6 18.8 246 297 A A S S+ 0 0 51 -2,-0.4 -67,-0.3 -23,-0.1 -1,-0.1 0.860 91.3 69.7 -56.1 -41.6 53.4 9.9 21.3 247 298 A S S >> S- 0 0 25 1,-0.1 3,-1.5 -69,-0.1 4,-0.6 -0.741 76.4-149.2 -86.7 114.6 49.9 11.3 21.7 248 299 A P G >4 S+ 0 0 33 0, 0.0 3,-1.4 0, 0.0 -1,-0.1 0.864 96.5 55.9 -50.0 -41.8 47.8 10.9 18.5 249 300 A R G 34 S+ 0 0 208 1,-0.3 -2,-0.0 0, 0.0 0, 0.0 0.692 101.2 59.2 -64.0 -23.0 45.8 14.1 19.1 250 301 A D G <4 S+ 0 0 69 -3,-1.5 -1,-0.3 2,-0.1 -4,-0.1 0.608 87.5 97.6 -79.9 -14.9 49.1 16.2 19.2 251 302 A R S << S- 0 0 13 -3,-1.4 -8,-0.2 -4,-0.6 2,-0.1 -0.443 82.5-108.4 -75.2 146.4 50.0 15.1 15.7 252 303 A P - 0 0 18 0, 0.0 -1,-0.1 0, 0.0 2,-0.1 -0.410 29.4-119.0 -70.4 154.6 49.2 17.4 12.7 253 304 A S > - 0 0 55 -2,-0.1 4,-2.5 1,-0.1 5,-0.1 -0.328 35.3 -99.2 -76.2 171.3 46.4 16.5 10.3 254 305 A I H > S+ 0 0 13 2,-0.2 4,-2.5 1,-0.2 5,-0.2 0.910 127.7 52.6 -58.9 -44.3 47.4 15.9 6.6 255 306 A D H > S+ 0 0 74 1,-0.2 4,-0.8 2,-0.2 -1,-0.2 0.901 111.3 46.2 -60.1 -40.9 46.2 19.6 5.9 256 307 A Q H 4 S+ 0 0 97 2,-0.2 4,-0.4 1,-0.2 3,-0.4 0.867 109.9 53.3 -67.7 -42.2 48.5 20.9 8.7 257 308 A I H >< S+ 0 0 4 -4,-2.5 3,-1.3 1,-0.2 6,-0.4 0.926 109.0 50.4 -56.7 -47.9 51.4 18.7 7.4 258 309 A L H 3< S+ 0 0 44 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.695 108.3 52.1 -67.7 -19.0 51.0 20.3 3.9 259 310 A R T 3< S+ 0 0 156 -4,-0.8 -1,-0.3 -3,-0.4 -2,-0.2 0.449 87.5 110.1 -97.4 -0.1 51.0 23.8 5.4 260 311 A H S X> S- 0 0 37 -3,-1.3 4,-2.4 -4,-0.4 3,-1.4 -0.405 84.0-111.6 -71.5 148.6 54.3 23.2 7.3 261 312 A D H 3>>S+ 0 0 71 1,-0.3 4,-2.5 2,-0.2 5,-0.5 0.741 113.0 71.7 -52.0 -34.7 57.5 25.0 6.1 262 313 A F H 345S+ 0 0 0 -27,-0.4 -1,-0.3 1,-0.2 4,-0.3 0.898 116.0 23.5 -50.1 -43.6 59.0 21.7 5.0 263 314 A F H <45S+ 0 0 1 -3,-1.4 -2,-0.2 -6,-0.4 -1,-0.2 0.860 125.6 49.4 -89.4 -44.0 56.4 21.8 2.1 264 315 A T H <5S+ 0 0 83 -4,-2.4 -3,-0.2 1,-0.2 -2,-0.2 0.750 122.1 30.8 -69.5 -31.6 55.6 25.6 1.9 265 316 A K T <5S+ 0 0 162 -4,-2.5 -1,-0.2 -5,-0.2 -3,-0.2 0.514 106.5 90.5-106.4 -8.2 59.2 26.8 1.8 266 317 A G S - 0 0 59 0, 0.0 3,-1.4 0, 0.0 4,-0.1 -0.439 23.3-119.7 -71.8 153.9 63.5 11.4 -13.8 274 325 A I G > S+ 0 0 73 1,-0.2 3,-1.9 2,-0.2 4,-0.2 0.828 112.9 68.8 -55.4 -37.2 63.1 7.6 -14.2 275 326 A S G >> S+ 0 0 53 1,-0.3 4,-2.1 2,-0.2 3,-2.0 0.762 80.8 75.1 -53.2 -31.2 66.9 7.4 -13.4 276 327 A S G <4 S+ 0 0 0 -3,-1.4 -1,-0.3 1,-0.3 -2,-0.2 0.574 80.2 73.9 -62.6 -9.7 66.1 8.5 -9.7 277 328 A C G <4 S+ 0 0 14 -3,-1.9 -1,-0.3 1,-0.1 -175,-0.3 0.726 116.0 15.9 -70.3 -31.6 64.8 4.9 -9.2 278 329 A V T <4 S+ 0 0 104 -3,-2.0 2,-0.3 1,-0.3 -2,-0.2 0.618 132.1 19.0-117.3 -25.9 68.3 3.6 -9.1 279 330 A T S < S- 0 0 78 -4,-2.1 -1,-0.3 1,-0.0 -176,-0.1 -0.898 95.2 -65.7-143.4 168.4 70.7 6.6 -8.6 280 331 A V 0 0 91 -2,-0.3 -3,-0.1 1,-0.1 -174,-0.1 -0.316 360.0 360.0 -56.2 135.8 70.6 10.3 -7.4 281 332 A P 0 0 89 0, 0.0 -1,-0.1 0, 0.0 -7,-0.0 -0.247 360.0 360.0 -59.5 360.0 68.5 12.4 -9.8