==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=15-FEB-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDOREDUCTASE 20-AUG-12 4B7K . COMPND 2 MOLECULE: HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR R.CHOWDHURY,W.GE,C.J.SCHOFIELD . 353 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16853.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 233 66.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 11 3.1 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 68 19.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 23 6.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 44 12.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 69 19.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 3 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 2 1 1 0 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 1 2 4 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 12 A G 0 0 45 0, 0.0 250,-0.3 0, 0.0 3,-0.1 0.000 360.0 360.0 360.0-131.8 12.4 -37.0 22.4 2 13 A S - 0 0 16 1,-0.3 251,-0.2 28,-0.1 27,-0.0 0.113 360.0-124.1 -91.3 20.7 12.0 -33.2 23.0 3 14 A G - 0 0 53 2,-0.1 -1,-0.3 249,-0.1 3,-0.1 0.073 58.0 -24.0 62.2-179.6 10.6 -33.7 26.5 4 15 A E S S- 0 0 89 1,-0.1 13,-0.0 -3,-0.1 2,-0.0 -0.385 85.4 -93.2 -62.6 134.2 7.3 -32.3 27.7 5 16 A P - 0 0 54 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 -0.273 47.3-114.5 -51.9 122.6 6.2 -29.3 25.6 6 17 A R - 0 0 62 -3,-0.1 9,-1.8 1,-0.1 2,-0.4 -0.216 26.1-120.5 -59.1 150.1 7.5 -26.1 27.4 7 18 A E B -A 14 0A 121 7,-0.2 -1,-0.1 8,-0.1 3,-0.1 -0.829 25.3-120.8 -97.6 130.7 4.8 -23.7 28.7 8 19 A E > - 0 0 74 5,-1.6 3,-0.8 -2,-0.4 4,-0.4 -0.237 31.2 -99.6 -66.5 153.7 4.8 -20.1 27.5 9 20 A A T 3 S+ 0 0 88 1,-0.2 3,-0.3 2,-0.2 -1,-0.1 -0.474 108.5 34.4 -70.9 147.3 5.2 -17.1 29.8 10 21 A G T 3 S- 0 0 73 1,-0.2 -1,-0.2 -2,-0.1 -2,-0.1 0.728 128.4 -78.4 80.4 22.2 1.9 -15.5 30.7 11 22 A A S < S+ 0 0 93 -3,-0.8 -1,-0.2 1,-0.1 -2,-0.2 0.881 80.9 153.6 53.7 42.3 -0.1 -18.8 30.7 12 23 A L - 0 0 139 -4,-0.4 -1,-0.1 -3,-0.3 -3,-0.1 0.330 53.1-120.5 -85.2 12.3 -0.2 -18.7 26.9 13 24 A G - 0 0 19 -5,-0.3 -5,-1.6 2,-0.0 -1,-0.2 0.008 56.4 -18.4 76.9 175.0 -0.4 -22.4 26.9 14 25 A P B -A 7 0A 79 0, 0.0 -7,-0.2 0, 0.0 3,-0.1 -0.297 55.4-140.4 -55.9 131.8 1.8 -25.1 25.4 15 26 A A S S- 0 0 24 -9,-1.8 2,-0.3 1,-0.2 -8,-0.1 0.875 82.0 -13.3 -58.1 -41.3 4.0 -23.5 22.7 16 27 A W - 0 0 8 -10,-0.3 2,-0.3 0, 0.0 -1,-0.2 -0.930 68.2-135.7-153.6 167.9 3.5 -26.7 20.5 17 28 A D > - 0 0 73 -2,-0.3 3,-3.2 -3,-0.1 4,-0.2 -0.970 32.7 -99.3-135.9 152.0 2.2 -30.3 20.9 18 29 A E G > S+ 0 0 73 -2,-0.3 3,-2.8 1,-0.3 -1,-0.0 0.748 113.1 69.9 -35.3 -38.2 3.2 -33.8 19.8 19 30 A S G 3 S+ 0 0 87 1,-0.3 -1,-0.3 -3,-0.0 255,-0.0 0.664 90.8 63.7 -65.2 -11.3 0.9 -33.9 16.9 20 31 A Q G < S+ 0 0 30 -3,-3.2 254,-2.3 253,-0.1 2,-0.4 0.571 87.7 85.2 -87.9 -8.6 3.1 -31.3 15.2 21 32 A L S < S- 0 0 32 -3,-2.8 252,-0.0 -4,-0.2 251,-0.0 -0.792 79.0-124.4 -96.9 132.2 6.1 -33.6 15.1 22 33 A R - 0 0 45 -2,-0.4 2,-0.4 1,-0.1 -2,-0.1 -0.230 30.7-109.5 -67.7 163.8 6.6 -36.1 12.2 23 34 A S - 0 0 112 2,-0.0 2,-0.3 211,-0.0 -1,-0.1 -0.820 36.4-179.1-104.1 134.6 7.0 -39.8 12.9 24 35 A Y - 0 0 35 -2,-0.4 210,-0.1 2,-0.2 209,-0.0 -0.920 35.7-122.8-133.1 159.0 10.2 -41.7 12.5 25 36 A S S S+ 0 0 67 208,-0.4 209,-0.0 -2,-0.3 -1,-0.0 0.398 84.2 79.9 -78.1 1.2 11.5 -45.2 13.0 26 37 A F S S- 0 0 22 220,-0.0 -2,-0.2 222,-0.0 2,-0.2 -0.782 73.2-121.4-118.0 159.4 14.2 -44.3 15.4 27 38 A P - 0 0 84 0, 0.0 222,-2.2 0, 0.0 2,-0.3 -0.530 28.3-167.0 -86.9 159.2 14.5 -43.5 19.1 28 39 A T E -b 249 0B 32 220,-0.2 222,-0.2 -2,-0.2 178,-0.0 -0.993 16.6-147.2-149.1 149.4 15.9 -40.3 20.5 29 40 A R E -b 250 0B 44 220,-2.3 222,-3.1 -2,-0.3 2,-0.3 -0.745 40.0 -98.6-107.3 160.9 17.1 -38.8 23.7 30 41 A P E -b 251 0B 75 0, 0.0 222,-0.2 0, 0.0 -28,-0.1 -0.643 28.5-122.3 -87.8 139.7 16.6 -35.0 24.4 31 42 A I - 0 0 7 220,-3.1 2,-0.1 -2,-0.3 20,-0.1 -0.491 41.5 -98.0 -73.0 144.5 19.3 -32.4 23.9 32 43 A P - 0 0 54 0, 0.0 20,-3.0 0, 0.0 2,-0.7 -0.425 28.4-151.7 -67.5 139.0 20.1 -30.5 27.1 33 44 A R E +h 52 0C 76 18,-0.2 2,-0.2 -2,-0.1 20,-0.2 -0.921 34.2 154.7-113.0 103.8 18.4 -27.0 27.6 34 45 A L E -h 53 0C 22 18,-2.2 20,-2.4 -2,-0.7 2,-0.3 -0.732 45.1-100.2-127.0 173.4 20.7 -24.9 29.7 35 46 A S > - 0 0 28 -2,-0.2 3,-2.1 18,-0.2 6,-0.3 -0.724 31.7-122.8 -92.5 144.2 21.6 -21.3 30.5 36 47 A Q T 3 S+ 0 0 70 -2,-0.3 -1,-0.1 1,-0.3 6,-0.1 0.671 115.2 59.4 -60.0 -16.6 24.7 -19.8 28.9 37 48 A S T 3 S+ 0 0 86 4,-0.1 -1,-0.3 5,-0.0 3,-0.0 0.632 82.1 103.3 -85.9 -16.8 25.9 -19.1 32.5 38 49 A D X> - 0 0 31 -3,-2.1 4,-1.3 1,-0.1 3,-0.6 -0.503 67.9-146.1 -69.5 127.5 25.6 -22.8 33.3 39 50 A P H 3> S+ 0 0 101 0, 0.0 4,-1.3 0, 0.0 -1,-0.1 0.802 97.3 64.8 -64.9 -27.1 29.1 -24.4 33.5 40 51 A R H 3> S+ 0 0 154 1,-0.2 4,-1.6 2,-0.2 5,-0.1 0.859 100.2 50.9 -63.8 -36.0 27.6 -27.7 32.1 41 52 A A H <> S+ 0 0 1 -3,-0.6 4,-1.8 -6,-0.3 -1,-0.2 0.898 107.6 52.1 -69.1 -38.2 26.8 -25.9 28.9 42 53 A E H X S+ 0 0 57 -4,-1.3 4,-1.5 1,-0.2 -1,-0.2 0.797 108.7 53.3 -67.1 -24.2 30.3 -24.6 28.6 43 54 A E H X S+ 0 0 117 -4,-1.3 4,-1.2 2,-0.2 -1,-0.2 0.840 106.8 50.8 -77.2 -35.4 31.4 -28.2 29.1 44 55 A L H <>S+ 0 0 23 -4,-1.6 5,-3.6 2,-0.2 -2,-0.2 0.822 111.7 46.2 -71.9 -34.2 29.2 -29.5 26.2 45 56 A I H ><5S+ 0 0 3 -4,-1.8 3,-2.0 3,-0.2 -2,-0.2 0.919 110.4 53.0 -74.5 -41.2 30.5 -26.9 23.7 46 57 A E H 3<5S+ 0 0 107 -4,-1.5 -2,-0.2 1,-0.3 -1,-0.2 0.820 112.3 45.9 -62.1 -30.3 34.1 -27.6 24.7 47 58 A N T 3<5S- 0 0 85 -4,-1.2 -1,-0.3 2,-0.1 -2,-0.2 0.112 116.8-117.7 -99.5 22.7 33.5 -31.3 24.1 48 59 A E T < 5 + 0 0 59 -3,-2.0 -3,-0.2 1,-0.2 -2,-0.1 0.899 67.6 139.8 40.7 56.8 31.8 -30.5 20.8 49 60 A E < - 0 0 79 -5,-3.6 -1,-0.2 160,-0.1 -2,-0.1 -0.981 57.6 -98.1-125.0 139.2 28.4 -31.9 22.0 50 61 A P + 0 0 5 0, 0.0 2,-0.3 0, 0.0 212,-0.1 -0.063 44.9 167.9 -54.3 157.3 25.1 -30.2 21.2 51 62 A V E - I 0 261C 0 210,-0.7 210,-2.4 -20,-0.1 2,-0.6 -0.879 31.1-132.5-169.4 136.9 23.4 -28.0 23.7 52 63 A V E -hI 33 260C 0 -20,-3.0 -18,-2.2 -2,-0.3 2,-0.5 -0.886 21.2-154.5 -98.7 120.1 20.4 -25.6 23.5 53 64 A L E -hI 34 259C 2 206,-3.5 206,-2.3 -2,-0.6 -18,-0.2 -0.840 8.1-170.0 -96.4 128.2 21.2 -22.3 25.2 54 65 A T S S+ 0 0 54 -20,-2.4 -19,-0.2 -2,-0.5 -1,-0.1 0.661 74.2 34.3 -93.9 -18.1 18.1 -20.4 26.4 55 66 A D S S+ 0 0 59 -21,-0.3 -1,-0.1 1,-0.1 203,-0.1 0.204 70.4 115.9-122.0 17.1 19.4 -16.9 27.4 56 67 A T - 0 0 4 201,-0.3 102,-0.1 -3,-0.2 -1,-0.1 0.855 59.1-147.6 -65.7 -33.4 22.2 -15.8 25.1 57 68 A N > + 0 0 97 200,-0.4 3,-1.2 -3,-0.1 98,-0.4 0.761 44.1 152.4 70.7 24.1 20.3 -12.8 23.6 58 69 A L T 3 S+ 0 0 1 1,-0.3 97,-1.7 199,-0.2 98,-0.1 0.895 78.3 14.2 -52.5 -48.4 22.4 -13.7 20.5 59 70 A V T >> S+ 0 0 4 95,-0.2 3,-1.2 139,-0.1 4,-0.9 -0.181 81.1 144.0-121.5 37.2 19.8 -12.3 18.1 60 71 A Y G X4 S+ 0 0 156 -3,-1.2 3,-1.3 1,-0.3 4,-0.3 0.888 72.0 53.3 -43.2 -51.7 17.6 -10.4 20.6 61 72 A P G >4 S+ 0 0 18 0, 0.0 3,-0.9 0, 0.0 -1,-0.3 0.810 103.8 55.4 -55.8 -36.4 17.0 -7.6 18.0 62 73 A A G X4 S+ 0 0 0 -3,-1.2 3,-2.7 1,-0.2 -2,-0.2 0.633 80.4 89.1 -76.1 -13.9 15.7 -10.0 15.3 63 74 A L G << S+ 0 0 67 -3,-1.3 -1,-0.2 -4,-0.9 -3,-0.1 0.763 84.9 56.6 -56.2 -21.5 13.0 -11.4 17.6 64 75 A K G < S+ 0 0 105 -3,-0.9 -1,-0.3 -4,-0.3 5,-0.2 0.568 84.7 117.8 -85.1 -8.1 10.7 -8.6 16.3 65 76 A W < + 0 0 6 -3,-2.7 2,-0.3 -4,-0.1 3,-0.1 -0.239 29.5 149.0 -61.3 147.6 11.3 -9.8 12.8 66 77 A D > - 0 0 61 1,-0.1 4,-1.9 134,-0.0 5,-0.2 -0.890 62.7 -82.7-165.0 168.1 8.3 -11.1 10.7 67 78 A L H > S+ 0 0 35 -2,-0.3 4,-2.8 1,-0.2 5,-0.3 0.907 125.5 50.2 -51.1 -50.1 7.6 -10.9 6.9 68 79 A E H > S+ 0 0 148 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.939 111.1 48.1 -54.2 -53.0 6.3 -7.3 6.9 69 80 A Y H > S+ 0 0 33 1,-0.2 4,-1.4 2,-0.2 -1,-0.2 0.842 116.4 43.7 -56.5 -39.4 9.2 -5.9 8.9 70 81 A L H X S+ 0 0 0 -4,-1.9 4,-4.8 2,-0.2 5,-0.3 0.929 110.6 51.1 -75.1 -48.4 11.8 -7.6 6.6 71 82 A Q H < S+ 0 0 67 -4,-2.8 4,-0.3 1,-0.2 -2,-0.2 0.938 114.3 49.9 -52.8 -44.3 10.1 -6.9 3.3 72 83 A E H < S+ 0 0 145 -4,-2.5 -1,-0.2 -5,-0.3 -2,-0.2 0.849 130.9 12.6 -64.0 -37.1 10.1 -3.3 4.6 73 84 A N H < S+ 0 0 31 -4,-1.4 71,-0.9 -5,-0.2 74,-0.5 0.534 95.7 93.5-122.5 -5.7 13.8 -3.2 5.6 74 85 A I S < S- 0 0 1 -4,-4.8 3,-0.3 1,-0.2 2,-0.2 0.686 84.1-133.4 -65.7 -16.4 15.7 -6.2 4.2 75 86 A G - 0 0 26 -4,-0.3 39,-0.3 -5,-0.3 -1,-0.2 -0.605 24.5 -67.5 101.5-162.6 16.7 -4.1 1.2 76 87 A N S S+ 0 0 119 66,-0.7 -1,-0.1 -2,-0.2 67,-0.1 0.050 80.9 120.2-126.2 30.1 16.7 -4.9 -2.6 77 88 A G S S- 0 0 14 65,-0.5 37,-0.4 -3,-0.3 2,-0.3 -0.197 71.0 -88.0 -80.7 179.5 19.4 -7.6 -3.1 78 89 A D - 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