==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER RIFAMYCIN BIOSYNTHESIS (RIFD GENE) 11-FEB-99 1B9I . COMPND 2 MOLECULE: PROTEIN (3-AMINO-5-HYDROXYBENZOIC ACID SYNTHASE); . SOURCE 2 ORGANISM_SCIENTIFIC: AMYCOLATOPSIS MEDITERRANEI; . AUTHOR J.C.EADS,M.BEEBY,G.SCAPIN,T.-W.YU,H.G.FLOSS . 384 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 15989.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 267 69.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 20 5.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 33 8.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 15 3.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 51 13.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 128 33.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 2 1 1 0 4 2 1 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 2 1 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 5 A K 0 0 155 0, 0.0 3,-0.1 0, 0.0 311,-0.0 0.000 360.0 360.0 360.0 177.4 13.8 63.4 29.7 2 6 A A - 0 0 48 1,-0.1 310,-0.1 374,-0.0 371,-0.1 -0.181 360.0 -99.1 -58.5 151.0 14.1 59.8 28.7 3 7 A P - 0 0 16 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 -0.251 37.7-133.5 -64.2 160.2 17.5 58.2 28.9 4 8 A E - 0 0 158 -3,-0.1 365,-0.1 358,-0.0 309,-0.0 -0.944 15.7-160.8-126.6 141.3 19.5 57.9 25.6 5 9 A F - 0 0 21 -2,-0.4 357,-0.2 360,-0.1 356,-0.1 -0.867 31.4 -90.6-118.2 154.9 21.3 54.9 24.3 6 10 A P - 0 0 42 0, 0.0 358,-0.1 0, 0.0 359,-0.1 -0.194 52.6 -99.8 -60.9 144.1 24.1 54.6 21.7 7 11 A A - 0 0 61 2,-0.0 3,-0.1 0, 0.0 0, 0.0 -0.177 37.2-116.8 -59.9 156.6 22.9 54.0 18.1 8 12 A W S S+ 0 0 31 1,-0.2 2,-0.1 2,-0.0 174,-0.0 -0.890 90.0 28.5-152.0 136.3 22.8 50.7 16.3 9 13 A P S S- 0 0 45 0, 0.0 2,-0.3 0, 0.0 -1,-0.2 0.594 84.2-163.1 -66.3 175.6 24.2 49.8 14.0 10 14 A Q + 0 0 58 -2,-0.1 2,-0.3 -3,-0.1 -2,-0.0 -0.929 14.6 161.9-120.4 156.1 27.4 51.9 14.3 11 15 A Y + 0 0 151 -2,-0.3 2,-0.2 3,-0.0 233,-0.0 -0.969 9.6 173.9-156.3 175.1 30.0 52.7 11.8 12 16 A D >> - 0 0 80 -2,-0.3 4,-1.6 0, 0.0 3,-1.3 -0.712 63.6 -43.2-158.5-144.3 32.8 55.1 11.0 13 17 A D H 3> S+ 0 0 97 1,-0.3 4,-2.8 -2,-0.2 5,-0.4 0.736 124.4 68.7 -69.4 -27.6 35.5 55.5 8.4 14 18 A A H 3> S+ 0 0 41 1,-0.2 4,-1.8 2,-0.2 -1,-0.3 0.943 105.6 41.4 -53.9 -47.4 36.4 51.8 8.6 15 19 A E H <> S+ 0 0 9 -3,-1.3 4,-2.3 2,-0.2 -2,-0.2 0.863 114.9 52.5 -64.1 -52.4 33.0 51.1 6.9 16 20 A R H X S+ 0 0 127 -4,-1.6 4,-1.8 2,-0.2 -2,-0.2 0.979 114.3 40.2 -45.4 -61.0 33.4 54.1 4.5 17 21 A N H X S+ 0 0 100 -4,-2.8 4,-3.0 1,-0.2 -1,-0.2 0.833 112.7 58.3 -57.7 -37.5 36.8 53.0 3.3 18 22 A G H X S+ 0 0 0 -4,-1.8 4,-2.9 -5,-0.4 -1,-0.2 0.943 106.1 46.7 -61.8 -45.9 35.6 49.3 3.2 19 23 A L H X S+ 0 0 72 -4,-2.3 4,-2.3 2,-0.2 -1,-0.2 0.881 113.9 49.0 -65.5 -45.3 32.8 50.0 0.8 20 24 A V H X S+ 0 0 72 -4,-1.8 4,-3.0 2,-0.2 5,-0.2 0.939 110.8 50.4 -53.8 -51.4 35.2 52.1 -1.4 21 25 A R H X S+ 0 0 104 -4,-3.0 4,-0.9 1,-0.2 -2,-0.2 0.953 113.7 45.3 -56.5 -41.9 37.8 49.2 -1.3 22 26 A A H < S+ 0 0 0 -4,-2.9 5,-0.4 1,-0.2 3,-0.4 0.887 114.1 49.1 -65.6 -50.7 35.1 46.8 -2.3 23 27 A L H >< S+ 0 0 83 -4,-2.3 3,-1.5 1,-0.2 -2,-0.2 0.922 109.8 50.9 -50.7 -53.4 33.7 49.1 -5.0 24 28 A E H 3< S+ 0 0 151 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.519 88.0 77.0 -78.1 -2.2 37.2 49.8 -6.6 25 29 A Q T 3< S- 0 0 52 -4,-0.9 -1,-0.3 -3,-0.4 -2,-0.1 0.755 94.7-143.7 -65.7 -24.7 38.1 46.1 -6.9 26 30 A G S < S+ 0 0 45 -3,-1.5 2,-0.4 -4,-0.3 -2,-0.1 0.579 74.9 89.6 66.6 6.8 35.7 46.5 -9.9 27 31 A Q - 0 0 102 -5,-0.4 -2,-0.1 1,-0.1 -1,-0.1 -0.996 54.1-176.2-130.6 126.0 34.5 42.9 -9.1 28 32 A W + 0 0 133 -2,-0.4 207,-2.5 5,-0.1 208,-0.4 0.388 56.9 72.7-110.5 -1.6 31.6 42.6 -6.7 29 33 A W S >> S- 0 0 117 205,-0.2 3,-1.4 206,-0.1 4,-1.3 -0.771 90.9-106.1-109.5 160.3 31.0 38.9 -6.2 30 34 A R T 34 S+ 0 0 5 203,-0.5 7,-0.2 -2,-0.3 204,-0.1 0.771 113.5 66.1 -59.9 -28.8 33.3 36.6 -4.2 31 35 A M T 34 S+ 0 0 35 1,-0.2 -1,-0.3 3,-0.0 -4,-0.0 0.834 114.7 28.5 -68.0 -19.8 34.7 35.0 -7.4 32 36 A G T <4 S+ 0 0 38 -3,-1.4 -1,-0.2 0, 0.0 -2,-0.2 0.557 117.9 51.9-111.8 -19.7 36.4 38.2 -8.5 33 37 A G < - 0 0 2 -4,-1.3 4,-0.1 -7,-0.1 -5,-0.1 -0.558 65.4-136.9-102.8-167.4 37.2 40.1 -5.2 34 38 A D S > S+ 0 0 102 -2,-0.2 4,-2.4 2,-0.1 5,-0.3 0.337 79.3 91.3-127.5 -3.6 38.9 39.3 -1.9 35 39 A E H > S+ 0 0 6 2,-0.2 4,-2.7 1,-0.2 5,-0.2 0.944 93.0 40.0 -63.4 -53.0 36.5 40.9 0.7 36 40 A V H > S+ 0 0 0 1,-0.2 4,-2.8 2,-0.2 -1,-0.2 0.928 117.5 50.6 -60.8 -45.8 34.4 37.8 1.2 37 41 A N H > S+ 0 0 46 2,-0.2 4,-1.5 1,-0.2 -2,-0.2 0.885 114.9 41.9 -58.3 -49.7 37.5 35.6 1.2 38 42 A S H X S+ 0 0 38 -4,-2.4 4,-2.8 2,-0.2 5,-0.3 0.930 113.4 52.8 -60.3 -50.1 39.4 37.8 3.8 39 43 A F H X S+ 0 0 1 -4,-2.7 4,-3.2 -5,-0.3 5,-0.2 0.940 106.0 55.9 -55.2 -44.9 36.2 38.2 5.9 40 44 A E H X S+ 0 0 11 -4,-2.8 4,-2.5 1,-0.2 -1,-0.2 0.921 111.4 41.7 -56.6 -46.2 35.9 34.4 6.0 41 45 A R H X S+ 0 0 203 -4,-1.5 4,-2.2 2,-0.2 -1,-0.2 0.884 116.1 48.6 -67.1 -41.6 39.4 33.9 7.3 42 46 A E H X S+ 0 0 68 -4,-2.8 4,-2.3 2,-0.2 -2,-0.2 0.892 114.6 46.6 -62.9 -45.5 39.1 36.8 9.8 43 47 A F H X S+ 0 0 0 -4,-3.2 4,-1.2 -5,-0.3 -2,-0.2 0.898 113.9 46.0 -64.9 -50.5 35.7 35.5 11.0 44 48 A A H <>S+ 0 0 7 -4,-2.5 5,-3.1 -5,-0.2 3,-0.2 0.846 112.9 50.1 -54.8 -50.3 36.8 31.9 11.4 45 49 A A H ><5S+ 0 0 63 -4,-2.2 3,-2.7 3,-0.2 -2,-0.2 0.953 107.6 54.8 -56.0 -50.9 40.1 32.9 13.2 46 50 A H H 3<5S+ 0 0 49 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.770 115.1 39.9 -54.6 -29.4 38.0 35.1 15.6 47 51 A H T 3<5S- 0 0 2 -4,-1.2 123,-1.2 -3,-0.2 -1,-0.3 0.121 111.1-117.3-102.0 7.1 35.9 32.1 16.4 48 52 A G T < 5 + 0 0 19 -3,-2.7 150,-0.3 1,-0.2 -3,-0.2 0.724 64.9 149.4 62.1 21.9 38.7 29.5 16.5 49 53 A A < - 0 0 13 -5,-3.1 -1,-0.2 -6,-0.2 3,-0.1 -0.534 55.0-135.4 -91.4 154.0 37.1 27.6 13.6 50 54 A A S S+ 0 0 34 146,-1.8 2,-0.3 1,-0.3 -1,-0.1 0.800 89.2 4.5 -64.0 -43.6 38.9 25.6 10.9 51 55 A H E -A 196 0A 46 145,-1.9 145,-3.2 -7,-0.1 2,-0.4 -0.983 60.2-158.1-143.7 151.8 36.8 27.2 8.2 52 56 A A E -A 195 0A 6 -2,-0.3 2,-0.5 143,-0.2 143,-0.2 -0.965 2.5-163.0-127.3 146.7 34.1 29.8 7.7 53 57 A L E -A 194 0A 0 141,-3.2 141,-1.9 -2,-0.4 2,-0.2 -0.940 13.5-151.1-124.9 98.4 31.6 30.2 4.9 54 58 A A E +A 193 0A 0 -2,-0.5 179,-0.5 139,-0.2 139,-0.3 -0.615 25.8 175.7 -67.3 136.6 30.0 33.7 4.6 55 59 A V E -A 192 0A 0 137,-1.9 137,-2.1 -2,-0.2 177,-0.2 -0.802 45.0 -84.5-140.2 172.0 26.4 33.4 3.1 56 60 A T S S- 0 0 40 175,-1.5 2,-0.3 -2,-0.2 176,-0.1 0.881 97.7 -21.9 -56.3 -41.4 23.5 35.6 2.3 57 61 A N > - 0 0 37 134,-0.2 4,-2.0 133,-0.1 135,-0.4 -0.982 64.6 -94.3-162.6 173.1 21.9 35.5 5.8 58 62 A G H > S+ 0 0 9 133,-0.7 4,-2.3 -2,-0.3 5,-0.1 0.841 118.6 56.7 -68.1 -26.8 21.5 33.5 9.1 59 63 A T H > S+ 0 0 32 1,-0.2 4,-2.5 2,-0.2 -1,-0.2 0.949 110.4 44.6 -71.1 -39.7 18.5 31.6 8.0 60 64 A H H > S+ 0 0 51 2,-0.2 4,-3.0 1,-0.2 5,-0.2 0.881 106.2 59.1 -74.0 -30.0 20.4 30.3 5.0 61 65 A A H X S+ 0 0 0 -4,-2.0 4,-2.9 2,-0.2 -2,-0.2 0.957 109.7 46.6 -60.0 -40.2 23.4 29.5 7.1 62 66 A L H X S+ 0 0 3 -4,-2.3 4,-3.0 1,-0.2 5,-0.3 0.917 111.9 48.9 -63.3 -47.2 21.0 27.2 9.0 63 67 A E H X S+ 0 0 20 -4,-2.5 4,-2.0 2,-0.2 -1,-0.2 0.892 115.2 45.5 -57.2 -42.7 19.5 25.7 5.8 64 68 A L H X S+ 0 0 0 -4,-3.0 4,-2.8 -5,-0.2 5,-0.2 0.958 112.7 48.4 -66.3 -49.1 23.0 25.0 4.5 65 69 A A H X S+ 0 0 0 -4,-2.9 4,-1.7 -5,-0.2 -2,-0.2 0.973 114.7 46.7 -57.5 -49.3 24.4 23.6 7.7 66 70 A L H <>S+ 0 0 0 -4,-3.0 5,-3.1 1,-0.2 -1,-0.2 0.890 110.7 52.3 -55.2 -50.2 21.4 21.3 8.1 67 71 A Q H ><5S+ 0 0 55 -4,-2.0 3,-1.5 -5,-0.3 -1,-0.2 0.953 111.3 44.9 -55.5 -50.9 21.5 20.2 4.5 68 72 A V H 3<5S+ 0 0 16 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.733 107.8 60.1 -70.1 -16.7 25.2 19.2 4.7 69 73 A M T 3<5S- 0 0 19 -4,-1.7 -1,-0.3 -5,-0.2 -2,-0.2 0.188 127.8-100.6 -89.3 19.4 24.5 17.4 8.0 70 74 A G T < 5 + 0 0 45 -3,-1.5 -3,-0.2 1,-0.2 2,-0.2 0.683 64.5 162.1 78.7 21.7 22.0 15.3 6.1 71 75 A V < + 0 0 10 -5,-3.1 -1,-0.2 -6,-0.2 25,-0.0 -0.524 21.4 112.4 -78.8 140.1 18.7 17.0 7.0 72 76 A G > - 0 0 10 -2,-0.2 3,-2.5 23,-0.1 25,-0.3 -0.981 66.0 -27.7-178.1-175.6 15.9 16.1 4.8 73 77 A P T 3 S+ 0 0 108 0, 0.0 23,-0.2 0, 0.0 3,-0.1 -0.365 123.1 31.7 -53.7 133.8 12.6 14.4 4.2 74 78 A G T 3 S+ 0 0 47 21,-0.5 2,-0.2 1,-0.3 22,-0.1 0.220 103.6 98.1 97.7 -10.9 12.2 11.5 6.6 75 79 A T < - 0 0 16 -3,-2.5 22,-2.6 20,-0.1 2,-0.4 -0.651 59.7-141.8-111.9 168.2 14.3 13.2 9.3 76 80 A E E -ef 97 123B 31 46,-1.9 48,-2.9 -2,-0.2 49,-0.9 -0.949 6.9-157.7-121.7 144.1 13.6 15.1 12.5 77 81 A V E -ef 98 125B 0 20,-2.5 22,-3.0 -2,-0.4 2,-0.4 -0.984 12.7-141.9-124.7 123.5 15.4 18.1 13.9 78 82 A I E +ef 99 126B 0 47,-2.2 49,-3.0 -2,-0.4 20,-0.1 -0.632 30.7 166.0 -84.7 125.7 15.2 18.9 17.6 79 83 A V E -e 100 0B 0 20,-1.9 22,-2.1 -2,-0.4 2,-0.1 -0.983 43.8 -92.3-135.9 158.8 15.1 22.7 18.3 80 84 A P E -e 101 0B 1 0, 0.0 22,-0.2 0, 0.0 23,-0.1 -0.501 27.8-139.9 -66.9 140.8 14.2 24.9 21.3 81 85 A A S S+ 0 0 0 20,-2.7 241,-2.5 1,-0.1 2,-0.7 0.621 94.9 66.4 -77.2 -19.7 10.6 25.8 21.2 82 86 A F S S+ 0 0 1 19,-0.4 2,-0.3 239,-0.2 -1,-0.1 -0.892 82.4 87.3-100.1 107.8 11.6 29.2 22.4 83 87 A T S S- 0 0 3 -2,-0.7 2,-0.2 237,-0.5 237,-0.2 -0.959 84.4 -62.1 176.8 170.3 13.7 30.9 19.5 84 88 A F > - 0 0 110 -2,-0.3 3,-1.6 1,-0.1 4,-0.4 -0.563 55.7-112.4 -71.4 144.6 13.3 33.0 16.3 85 89 A I T >> S+ 0 0 39 1,-0.3 4,-3.2 -2,-0.2 3,-1.5 0.828 108.5 75.5 -56.3 -26.9 11.3 31.1 13.7 86 90 A S H 3> S+ 0 0 10 1,-0.3 4,-2.8 2,-0.2 -1,-0.3 0.884 84.0 67.2 -54.7 -32.7 14.3 30.7 11.4 87 91 A S H <4 S+ 0 0 1 -3,-1.6 4,-0.4 1,-0.2 -1,-0.3 0.876 117.5 22.3 -57.4 -40.4 15.7 27.9 13.7 88 92 A S H X> S+ 0 0 3 -3,-1.5 4,-2.5 -4,-0.4 3,-0.9 0.840 115.9 65.3 -93.8 -33.1 12.8 25.6 12.8 89 93 A Q H 3X S+ 0 0 68 -4,-3.2 4,-3.0 1,-0.3 5,-0.2 0.906 97.5 59.3 -56.4 -37.5 11.8 27.1 9.5 90 94 A A H 3X S+ 0 0 0 -4,-2.8 4,-0.9 -5,-0.3 -1,-0.3 0.877 107.5 42.7 -59.1 -43.4 15.2 26.0 8.1 91 95 A A H X4>S+ 0 0 0 -3,-0.9 5,-1.9 -4,-0.4 3,-0.8 0.941 112.7 55.0 -68.0 -40.7 14.5 22.3 8.8 92 96 A Q H ><5S+ 0 0 26 -4,-2.5 3,-2.1 1,-0.3 -2,-0.2 0.907 103.0 57.0 -55.0 -43.8 10.9 22.7 7.5 93 97 A R H 3<5S+ 0 0 187 -4,-3.0 -1,-0.3 1,-0.3 -2,-0.2 0.854 102.9 53.3 -61.7 -29.9 12.4 24.1 4.3 94 98 A L T <<5S- 0 0 28 -4,-0.9 -1,-0.3 -3,-0.8 -2,-0.2 0.492 122.7-105.3 -84.7 1.4 14.5 21.0 3.7 95 99 A G T < 5S+ 0 0 39 -3,-2.1 -21,-0.5 -4,-0.3 -3,-0.2 0.640 79.0 128.9 85.0 12.9 11.4 18.8 4.1 96 100 A A < - 0 0 1 -5,-1.9 2,-0.5 -23,-0.2 -1,-0.3 -0.428 62.9-105.2 -93.7 176.3 12.2 17.5 7.6 97 101 A V E -e 76 0B 41 -22,-2.6 -20,-2.5 -25,-0.3 2,-0.4 -0.907 26.4-142.5-104.4 125.1 10.1 17.5 10.7 98 102 A T E -e 77 0B 5 234,-1.1 -20,-0.2 -2,-0.5 -10,-0.1 -0.767 11.9-161.9 -87.0 130.6 10.9 20.1 13.4 99 103 A V E -e 78 0B 15 -22,-3.0 -20,-1.9 -2,-0.4 2,-0.2 -0.937 10.4-150.3-115.6 102.8 10.5 18.6 16.9 100 104 A P E -e 79 0B 0 0, 0.0 2,-0.3 0, 0.0 -22,-0.1 -0.525 15.2-170.9 -74.7 138.2 10.3 21.5 19.4 101 105 A V E -e 80 0B 3 -22,-2.1 -20,-2.7 -2,-0.2 -19,-0.4 -0.881 26.4 -93.0-128.2 154.9 11.6 20.8 22.9 102 106 A D - 0 0 9 242,-0.5 9,-2.9 -2,-0.3 2,-0.3 -0.023 34.1-143.6 -66.9 163.4 11.5 22.8 26.1 103 107 A V B -H 110 0C 0 7,-0.3 7,-0.2 -23,-0.1 245,-0.1 -0.869 31.3 -76.9-123.0 164.1 14.0 25.2 27.4 104 108 A D > - 0 0 62 5,-2.9 4,-0.7 -2,-0.3 6,-0.0 -0.340 34.1-131.4 -60.3 144.0 15.4 26.2 30.8 105 109 A A T 4 S+ 0 0 44 1,-0.2 -1,-0.1 2,-0.1 171,-0.0 0.743 100.8 30.9 -70.6 -25.2 13.3 28.4 33.0 106 110 A A T 4 S+ 0 0 46 3,-0.1 170,-4.1 169,-0.1 -1,-0.2 0.835 130.0 26.4-106.4 -42.8 16.0 30.7 33.7 107 111 A T T 4 S- 0 0 17 168,-0.3 27,-0.1 2,-0.1 -2,-0.1 0.732 91.5-136.4 -85.3 -28.7 18.6 31.0 30.9 108 112 A Y < + 0 0 3 -4,-0.7 2,-0.3 1,-0.3 -3,-0.1 0.674 54.9 141.2 76.5 24.1 15.9 30.0 28.3 109 113 A N - 0 0 5 1,-0.1 -5,-2.9 26,-0.1 -1,-0.3 -0.668 66.9 -73.7 -91.7 157.8 18.4 27.7 26.6 110 114 A L B -H 103 0C 3 19,-0.5 27,-0.4 -2,-0.3 -7,-0.3 -0.087 54.0-121.0 -50.4 132.8 17.4 24.3 25.1 111 115 A D > - 0 0 30 -9,-2.9 4,-2.3 1,-0.2 5,-0.2 -0.638 12.8-149.8 -86.0 123.7 16.8 21.9 28.0 112 116 A P H > S+ 0 0 21 0, 0.0 4,-2.9 0, 0.0 5,-0.2 0.955 95.9 48.5 -58.7 -39.7 19.1 18.8 27.9 113 117 A E H > S+ 0 0 154 1,-0.3 4,-2.3 2,-0.2 5,-0.2 0.933 110.0 53.3 -68.3 -41.1 16.7 16.4 29.6 114 118 A A H > S+ 0 0 24 1,-0.2 4,-1.0 2,-0.2 -1,-0.3 0.862 110.3 47.5 -60.9 -37.0 13.9 17.5 27.3 115 119 A V H >X S+ 0 0 0 -4,-2.3 3,-1.2 -3,-0.2 4,-1.1 0.916 106.0 57.1 -72.3 -43.1 16.1 16.8 24.3 116 120 A A H >< S+ 0 0 51 -4,-2.9 3,-1.0 1,-0.3 -2,-0.2 0.936 109.5 47.4 -47.6 -42.6 17.1 13.3 25.6 117 121 A A H 3< S+ 0 0 90 -4,-2.3 -1,-0.3 1,-0.2 -2,-0.2 0.796 109.5 52.5 -68.5 -28.2 13.4 12.4 25.8 118 122 A A H << S+ 0 0 19 -3,-1.2 -1,-0.2 -4,-1.0 -2,-0.2 0.562 81.1 117.9 -88.7 -9.0 12.7 13.8 22.3 119 123 A V << + 0 0 33 -4,-1.1 7,-0.0 -3,-1.0 -3,-0.0 -0.210 38.9 168.6 -59.2 148.8 15.4 11.8 20.6 120 124 A T > - 0 0 51 -44,-0.1 3,-1.4 28,-0.0 -44,-0.1 -0.963 52.6 -95.7-152.1 168.8 14.2 9.3 18.1 121 125 A P T 3 S+ 0 0 138 0, 0.0 -2,-0.1 0, 0.0 -45,-0.0 0.698 125.1 54.0 -66.1 -19.6 15.5 7.0 15.3 122 126 A R T 3 S+ 0 0 148 -47,-0.1 -46,-1.9 2,-0.0 2,-0.1 0.652 78.3 117.4 -89.7 -13.5 14.6 9.8 12.9 123 127 A T E < +f 76 0B 11 -3,-1.4 -46,-0.2 -48,-0.2 3,-0.1 -0.347 29.8 166.1 -62.0 120.3 16.6 12.5 14.8 124 128 A K E + 0 0 106 -48,-2.9 2,-0.3 1,-0.3 -47,-0.2 0.728 63.0 13.0-102.6 -30.8 19.3 13.8 12.4 125 129 A V E -f 77 0B 0 -49,-0.9 -47,-2.2 25,-0.2 2,-0.5 -0.997 55.1-149.5-142.9 146.6 20.4 17.0 14.3 126 130 A I E -fg 78 152B 0 25,-2.2 27,-2.4 -2,-0.3 -47,-0.2 -0.993 19.7-159.3-115.7 125.3 20.0 18.6 17.7 127 131 A M - 0 0 0 -49,-3.0 27,-0.2 -2,-0.5 -17,-0.1 -0.716 7.6-171.1-114.2 89.0 20.1 22.4 17.5 128 132 A P - 0 0 0 0, 0.0 27,-3.1 0, 0.0 2,-0.4 -0.432 12.7-151.3 -62.0 153.0 20.9 24.4 20.7 129 133 A V B -b 155 0A 3 25,-0.2 2,-1.5 27,-0.1 -19,-0.5 -0.983 14.6-132.6-119.9 132.9 20.4 28.2 20.3 130 134 A H > - 0 0 0 25,-1.3 3,-2.1 -2,-0.4 5,-0.2 -0.685 33.4-137.0 -92.0 93.4 22.6 30.4 22.5 131 135 A M G > - 0 0 1 -2,-1.5 3,-2.1 3,-0.3 -22,-0.1 -0.248 69.7 -19.4 -60.5 120.4 19.8 32.5 23.7 132 136 A A G 3 S- 0 0 0 1,-0.3 156,-0.9 155,-0.1 155,-0.9 0.646 128.7 -51.7 54.6 23.9 20.7 36.2 23.7 133 137 A G G < S+ 0 0 0 -3,-2.1 152,-1.6 1,-0.3 2,-0.7 0.310 109.8 120.7 103.8 -14.1 24.4 35.4 23.7 134 138 A L < - 0 0 2 -3,-2.1 -3,-0.3 150,-0.2 -1,-0.3 -0.764 64.5-124.3 -89.6 114.5 24.3 33.0 26.7 135 139 A M - 0 0 1 -2,-0.7 146,-0.1 28,-0.3 -26,-0.1 -0.244 18.8-121.8 -57.7 153.4 25.6 29.6 25.6 136 140 A A - 0 0 0 1,-0.1 2,-2.0 -28,-0.1 3,-0.2 -0.264 48.8 -73.8 -80.6 169.9 23.5 26.6 26.0 137 141 A D > + 0 0 33 -27,-0.4 4,-2.8 1,-0.2 5,-0.2 -0.453 57.3 173.6 -72.1 84.5 24.7 23.6 28.1 138 142 A M H > S+ 0 0 7 -2,-2.0 4,-3.0 1,-0.2 -1,-0.2 0.828 72.8 54.1 -73.7 -19.1 27.2 22.4 25.5 139 143 A D H > S+ 0 0 63 2,-0.2 4,-3.3 -3,-0.2 5,-0.2 0.989 112.9 39.7 -70.4 -51.8 28.6 19.7 27.8 140 144 A A H > S+ 0 0 30 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.965 119.8 48.7 -63.9 -41.0 25.3 18.0 28.7 141 145 A L H X S+ 0 0 0 -4,-2.8 4,-2.6 2,-0.2 -1,-0.2 0.930 108.7 52.1 -66.3 -44.9 24.3 18.5 25.1 142 146 A A H X S+ 0 0 50 -4,-3.0 4,-2.2 -5,-0.2 -2,-0.2 0.949 108.6 53.0 -59.4 -36.4 27.7 17.0 23.8 143 147 A K H X S+ 0 0 130 -4,-3.3 4,-2.5 2,-0.2 3,-0.3 0.960 108.2 47.2 -63.9 -45.9 27.1 14.0 26.1 144 148 A I H X S+ 0 0 24 -4,-2.4 4,-3.3 1,-0.3 5,-0.4 0.928 108.6 59.8 -60.0 -36.3 23.6 13.3 24.6 145 149 A S H X S+ 0 0 24 -4,-2.6 4,-2.5 2,-0.2 5,-0.4 0.895 108.2 41.5 -55.2 -47.0 25.2 13.7 21.3 146 150 A A H < S+ 0 0 77 -4,-2.2 -2,-0.2 -3,-0.3 -1,-0.2 0.969 114.0 51.2 -69.6 -44.3 27.6 10.9 21.9 147 151 A D H < S+ 0 0 111 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.926 124.6 27.8 -60.9 -44.7 25.1 8.6 23.5 148 152 A T H < S- 0 0 62 -4,-3.3 -1,-0.2 -5,-0.2 -2,-0.2 0.746 97.0-131.5 -87.7 -27.7 22.7 9.0 20.7 149 153 A G < + 0 0 56 -4,-2.5 -3,-0.2 -5,-0.4 -4,-0.1 0.623 60.1 138.8 84.9 11.8 25.1 9.7 17.8 150 154 A V - 0 0 11 -5,-0.4 -1,-0.3 -6,-0.4 -25,-0.2 -0.825 51.6-131.0 -94.5 114.3 22.9 12.7 16.8 151 155 A P - 0 0 62 0, 0.0 -25,-2.2 0, 0.0 2,-0.3 -0.376 16.6-125.2 -61.3 152.8 25.3 15.5 15.9 152 156 A L B -g 126 0B 12 -27,-0.2 23,-0.5 21,-0.1 2,-0.4 -0.789 15.8-162.4 -97.4 151.1 24.7 19.0 17.3 153 157 A L - 0 0 0 -27,-2.4 2,-0.7 -2,-0.3 23,-0.2 -0.999 16.5-140.5-131.7 119.8 24.3 22.2 15.3 154 158 A Q E - c 0 176A 0 21,-2.5 23,-2.5 -2,-0.4 2,-1.7 -0.799 1.6-153.0 -85.4 121.8 24.8 25.5 17.1 155 159 A D E +bc 129 177A 8 -27,-3.1 -25,-1.3 -2,-0.7 3,-0.4 -0.654 26.3 170.1 -89.4 94.2 22.5 28.2 16.2 156 160 A A > + 0 0 0 -2,-1.7 3,-1.6 21,-1.1 23,-0.2 0.188 29.1 125.1 -95.2 32.4 24.9 31.0 17.2 157 161 A A T 3 S+ 0 0 10 1,-0.3 28,-0.3 21,-0.2 3,-0.3 0.773 83.5 37.7 -57.8 -31.9 23.0 34.0 15.7 158 162 A H T 3 S+ 0 0 7 -3,-0.4 129,-0.5 1,-0.2 -1,-0.3 0.559 108.1 69.0 -96.3 -4.4 23.0 35.7 19.1 159 163 A A X + 0 0 0 -3,-1.6 3,-1.7 126,-0.1 2,-0.3 -0.177 50.9 157.6-117.3 45.5 26.5 34.6 20.2 160 164 A H T 3 S+ 0 0 0 -3,-0.3 -3,-0.0 1,-0.3 18,-0.0 -0.522 84.0 7.6 -65.9 130.9 29.2 36.3 18.1 161 165 A G T 3 S+ 0 0 8 -2,-0.3 -1,-0.3 1,-0.2 2,-0.1 0.539 96.9 147.3 74.7 19.6 32.4 36.1 20.2 162 166 A A < - 0 0 0 -3,-1.7 7,-0.8 -6,-0.1 2,-0.3 -0.340 32.3-150.0 -86.9 157.7 30.8 33.9 23.0 163 167 A R E -IJ 168 283D 77 120,-2.7 120,-1.6 5,-0.2 2,-0.4 -0.978 12.2-165.8-138.8 139.5 32.7 31.3 25.0 164 168 A W E > S-I 167 0D 0 3,-2.0 3,-1.6 -2,-0.3 117,-0.2 -0.985 83.8 -18.1-121.3 114.9 31.8 28.1 26.7 165 169 A Q T 3 S- 0 0 88 115,-3.5 -1,-0.1 -2,-0.4 116,-0.1 0.950 128.9 -52.5 54.4 53.5 34.3 26.7 29.2 166 170 A G T 3 S+ 0 0 48 114,-0.3 2,-0.4 1,-0.2 -1,-0.3 0.432 115.2 120.3 66.6 -2.9 37.1 28.9 27.7 167 171 A K E < -I 164 0D 78 -3,-1.6 -3,-2.0 1,-0.0 -1,-0.2 -0.800 61.3-124.6-102.8 141.1 36.3 27.6 24.2 168 172 A R E > -I 163 0D 82 -2,-0.4 3,-3.4 -5,-0.2 -5,-0.2 -0.352 34.6-100.0 -77.3 162.4 35.2 29.7 21.2 169 173 A V G > S+ 0 0 0 -7,-0.8 3,-0.8 1,-0.3 5,-0.3 0.905 126.2 48.6 -51.0 -39.0 32.1 28.9 19.3 170 174 A G G 3 S+ 0 0 1 -123,-1.2 28,-0.4 1,-0.2 3,-0.3 0.557 101.6 64.0 -83.3 7.9 34.2 27.3 16.7 171 175 A E G < S+ 0 0 75 -3,-3.4 -1,-0.2 1,-0.2 -2,-0.1 0.102 77.2 87.4-112.0 23.0 36.2 25.2 19.2 172 176 A L S < S- 0 0 22 -3,-0.8 -1,-0.2 2,-0.3 -2,-0.1 0.113 99.9-113.6-104.4 5.8 33.3 23.1 20.5 173 177 A D S S+ 0 0 131 -3,-0.3 2,-0.4 1,-0.1 -21,-0.1 0.604 84.2 97.0 73.3 7.7 33.5 20.4 17.8 174 178 A S S S- 0 0 10 -5,-0.3 -2,-0.3 -23,-0.1 -1,-0.1 -0.981 79.7-106.0-126.3 150.2 30.2 21.2 16.2 175 179 A I - 0 0 3 -23,-0.5 -21,-2.5 -2,-0.4 2,-0.3 -0.316 42.0-167.9 -62.4 152.0 29.3 23.2 13.1 176 180 A A E -cD 154 195A 0 19,-2.1 19,-3.1 -23,-0.2 2,-0.3 -0.996 10.0-146.9-141.1 154.1 27.7 26.6 14.1 177 181 A T E -cD 155 194A 0 -23,-2.5 -21,-1.1 -2,-0.3 2,-0.3 -0.795 10.6-165.2-121.7 149.7 25.8 29.3 12.2 178 182 A F E - D 0 193A 0 15,-2.4 15,-1.7 -2,-0.3 2,-0.3 -0.972 10.0-143.0-127.2 166.5 25.6 33.1 12.6 179 183 A S E - D 0 192A 12 -2,-0.3 13,-0.3 13,-0.2 7,-0.3 -0.911 9.1-170.9-122.7 145.8 23.4 36.0 11.5 180 184 A F + 0 0 0 11,-3.5 8,-1.7 -2,-0.3 9,-0.5 -0.078 36.3 150.7-123.4 27.7 24.6 39.5 10.6 181 185 A Q B > -k 189 0E 69 10,-0.3 3,-2.6 6,-0.2 9,-0.3 -0.163 65.3 -90.0 -56.5 159.2 21.1 40.8 10.3 182 186 A N T 3 S+ 0 0 77 7,-1.7 -1,-0.1 1,-0.3 8,-0.1 0.641 125.0 44.7 -49.2 -38.6 20.7 44.5 11.1 183 187 A G T 3 S+ 0 0 13 6,-0.2 -1,-0.3 3,-0.1 177,-0.2 0.476 91.4 111.5 -88.9 -2.3 20.0 44.2 14.9 184 188 A K S < S- 0 0 20 -3,-2.6 3,-0.1 2,-0.1 -26,-0.1 -0.078 86.9 -98.9 -69.4 169.4 22.8 41.6 15.5 185 189 A L S S+ 0 0 0 -28,-0.3 2,-0.3 1,-0.2 -1,-0.1 0.654 115.8 17.9 -69.2 -24.4 26.0 42.2 17.5 186 190 A M S S+ 0 0 0 -7,-0.3 2,-0.3 -5,-0.2 -1,-0.2 -0.961 88.6 171.3-140.5 139.4 27.9 42.8 14.2 187 191 A T - 0 0 3 -2,-0.3 -6,-0.2 53,-0.1 -5,-0.1 -0.986 45.8-171.5-147.1 154.4 26.0 43.6 11.0 188 192 A A S S- 0 0 26 -8,-1.7 2,-1.3 -2,-0.3 -7,-0.1 -0.083 73.6 -94.9-129.3 28.4 25.9 44.6 7.4 189 193 A G B S+k 181 0E 20 -9,-0.5 -7,-1.7 -8,-0.1 2,-0.3 -0.333 109.9 23.9 88.3 -55.8 22.1 44.9 7.4 190 194 A E S S+ 0 0 118 -2,-1.3 2,-0.2 -9,-0.3 -133,-0.1 -0.985 82.0 103.2-134.0 153.5 22.0 41.3 6.1 191 195 A G - 0 0 0 -2,-0.3 -11,-3.5 -4,-0.1 -133,-0.7 -0.753 28.4-165.6 156.9 163.4 24.4 38.4 6.2 192 196 A G E -AD 55 179A 0 -137,-2.1 -137,-1.9 -135,-0.4 2,-0.3 -0.905 5.3-152.0-154.9 179.8 25.3 35.1 7.7 193 197 A A E -AD 54 178A 1 -15,-1.7 -15,-2.4 -139,-0.3 2,-0.4 -0.977 11.8-146.5-159.4 154.1 28.0 32.5 8.1 194 198 A V E -AD 53 177A 0 -141,-1.9 -141,-3.2 -2,-0.3 2,-0.4 -0.984 22.3-160.7-116.9 128.6 28.5 28.8 8.7 195 199 A V E -AD 52 176A 0 -19,-3.1 -19,-2.1 -2,-0.4 -143,-0.2 -0.932 2.3-155.8-119.3 140.5 31.7 28.0 10.8 196 200 A F E -A 51 0A 0 -145,-3.2 -145,-1.9 -2,-0.4 -146,-1.8 -0.936 10.6-134.6-122.8 124.5 33.2 24.5 10.8 197 201 A P > - 0 0 2 0, 0.0 3,-2.0 0, 0.0 -148,-0.1 -0.434 45.5 -71.7 -68.0 168.1 35.3 23.1 13.6 198 202 A D T 3 S+ 0 0 132 -28,-0.4 -147,-0.0 -150,-0.3 -149,-0.0 -0.254 123.6 35.3 -57.6 138.6 38.6 21.3 13.0 199 203 A G T 3 S+ 0 0 71 -3,-0.1 -1,-0.3 -149,-0.0 3,-0.2 0.358 94.1 90.3 90.0 -1.7 37.8 17.9 11.4 200 204 A E X> + 0 0 48 -3,-2.0 4,-2.1 1,-0.2 3,-0.6 0.119 39.8 124.3-117.6 30.2 34.9 19.0 9.3 201 205 A T H 3> S+ 0 0 61 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.861 70.7 57.6 -53.9 -43.5 36.6 20.0 6.1 202 206 A E H 3> S+ 0 0 152 -3,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.886 108.0 45.3 -55.6 -44.1 34.5 17.6 4.0 203 207 A K H <> S+ 0 0 67 -3,-0.6 4,-3.4 2,-0.2 -1,-0.2 0.872 110.6 55.7 -69.9 -35.3 31.2 19.2 5.0 204 208 A Y H X S+ 0 0 37 -4,-2.1 4,-3.0 2,-0.2 -2,-0.2 0.935 109.2 45.9 -59.1 -52.8 32.8 22.6 4.5 205 209 A E H X S+ 0 0 105 -4,-2.4 4,-1.9 2,-0.2 -2,-0.2 0.892 115.4 46.5 -59.0 -49.0 33.6 21.7 0.9 206 210 A T H X S+ 0 0 47 -4,-2.3 4,-3.3 2,-0.2 5,-0.2 0.932 111.2 52.8 -59.4 -44.6 30.1 20.2 0.3 207 211 A A H X S+ 0 0 0 -4,-3.4 4,-1.6 2,-0.2 -2,-0.2 0.945 107.2 51.5 -56.7 -48.3 28.6 23.4 1.9 208 212 A F H X S+ 0 0 13 -4,-3.0 4,-0.5 1,-0.2 3,-0.4 0.919 112.4 47.6 -53.2 -50.4 30.6 25.6 -0.5 209 213 A L H ><>S+ 0 0 40 -4,-1.9 5,-1.5 1,-0.2 3,-1.4 0.941 111.9 47.7 -57.9 -49.4 29.2 23.5 -3.4 210 214 A R H 3<5S+ 0 0 53 -4,-3.3 19,-2.3 1,-0.3 3,-0.5 0.661 109.9 53.9 -66.5 -21.2 25.6 23.6 -2.2 211 215 A H H 3<5S+ 0 0 0 -4,-1.6 20,-3.0 -3,-0.4 21,-0.4 0.461 107.6 51.8 -88.4 -10.1 25.8 27.4 -1.6 212 216 A S B X<5S-L 230 0F 6 -3,-1.4 3,-2.1 -4,-0.5 18,-0.2 -0.304 127.1 -85.6-119.8 49.9 27.0 28.1 -5.1 213 217 A C T 3 5S- 0 0 59 16,-3.2 -3,-0.2 -3,-0.5 17,-0.1 0.877 81.7 -68.5 53.9 36.3 24.4 26.2 -7.3 214 218 A G T 3 - 0 0 34 0, 0.0 3,-2.5 0, 0.0 6,-0.1 -0.207 28.8-117.0 -52.3 142.1 33.0 23.8 -8.3 217 221 A R T 3 S+ 0 0 112 1,-0.3 -2,-0.0 3,-0.0 -8,-0.0 0.766 115.0 37.0 -54.4 -36.4 34.9 27.1 -7.5 218 222 A D T 3 S+ 0 0 140 2,-0.0 -1,-0.3 0, 0.0 2,-0.2 0.159 84.7 127.1-100.0 5.8 37.0 26.5 -10.6 219 223 A D < + 0 0 26 -3,-2.5 -4,-0.0 1,-0.1 5,-0.0 -0.532 24.8 171.7 -61.0 141.9 34.5 25.0 -13.0 220 224 A R S S+ 0 0 178 -2,-0.2 -1,-0.1 3,-0.0 -3,-0.0 0.294 72.1 57.1-119.0 -13.3 34.3 26.7 -16.4 221 225 A R S S- 0 0 157 2,-0.0 3,-0.1 0, 0.0 -2,-0.0 0.346 109.4-104.5-116.0 19.6 32.0 24.2 -18.2 222 226 A Y + 0 0 162 1,-0.2 2,-1.9 -6,-0.1 -3,-0.0 0.833 56.1 163.0 63.9 40.4 28.8 24.1 -16.0 223 227 A F - 0 0 131 -7,-0.1 2,-0.2 2,-0.0 -1,-0.2 -0.416 20.4-168.8 -85.3 70.4 29.6 20.7 -14.4 224 228 A H - 0 0 95 -2,-1.9 -9,-0.2 1,-0.1 -10,-0.1 -0.443 3.8-168.2 -61.8 122.1 27.1 21.3 -11.5 225 229 A K + 0 0 131 -11,-3.2 2,-0.3 -2,-0.2 -1,-0.1 0.888 54.7 0.6 -89.1 -42.5 27.8 18.5 -9.0 226 230 A I S S- 0 0 58 -12,-0.3 -1,-0.2 -17,-0.1 0, 0.0 -0.928 78.6 -84.0-144.0 168.3 24.9 18.5 -6.5 227 231 A A + 0 0 67 -2,-0.3 2,-0.3 -3,-0.1 -13,-0.2 -0.131 64.2 106.8 -65.5 165.7 21.7 20.2 -5.6 228 232 A G - 0 0 40 -15,-0.1 2,-0.2 -17,-0.1 -17,-0.2 -0.915 53.3-102.4 160.5-139.0 21.6 23.4 -3.6 229 233 A S - 0 0 61 -19,-2.3 -16,-3.2 -2,-0.3 2,-0.6 -0.798 39.7 -81.7-160.7-168.0 20.9 27.1 -4.1 230 234 A N B +L 212 0F 74 -2,-0.2 -18,-0.2 -18,-0.2 -19,-0.1 -0.984 49.1 154.5-113.3 122.2 22.8 30.3 -4.3 231 235 A M + 0 0 6 -20,-3.0 -175,-1.5 -2,-0.6 -174,-0.1 -0.002 24.2 148.1-131.2 32.4 23.7 31.7 -0.8 232 236 A R - 0 0 64 -21,-0.4 2,-0.4 -177,-0.2 -177,-0.2 -0.253 41.1-137.0 -68.2 137.5 26.7 33.7 -1.9 233 237 A L - 0 0 6 -179,-0.5 -203,-0.5 -2,-0.1 -197,-0.1 -0.837 21.3-121.5 -94.1 143.1 27.5 37.0 0.0 234 238 A N > - 0 0 63 -2,-0.4 4,-2.2 -205,-0.1 -205,-0.2 -0.319 17.8-115.3 -82.8 160.0 28.5 40.1 -2.0 235 239 A E H > S+ 0 0 0 -207,-2.5 4,-2.1 2,-0.2 -206,-0.1 0.749 111.7 57.6 -67.9 -32.7 31.7 42.0 -1.6 236 240 A F H > S+ 0 0 61 -208,-0.4 4,-2.1 2,-0.2 5,-0.2 0.977 109.3 44.9 -60.9 -53.8 30.1 45.2 -0.3 237 241 A S H > S+ 0 0 24 1,-0.2 4,-2.5 2,-0.2 -2,-0.2 0.923 111.9 54.0 -52.2 -47.2 28.5 43.3 2.6 238 242 A A H X S+ 0 0 0 -4,-2.2 4,-2.0 1,-0.2 -1,-0.2 0.908 105.9 51.1 -60.8 -41.0 31.7 41.5 3.4 239 243 A S H X S+ 0 0 1 -4,-2.1 4,-1.3 2,-0.2 -1,-0.2 0.911 110.5 48.3 -67.8 -37.5 33.7 44.7 3.6 240 244 A V H X S+ 0 0 24 -4,-2.1 4,-1.7 1,-0.2 3,-0.4 0.953 110.0 54.3 -64.5 -33.7 31.2 46.2 6.1 241 245 A L H X S+ 0 0 0 -4,-2.5 4,-2.3 1,-0.3 -1,-0.2 0.787 102.4 56.8 -67.0 -39.4 31.3 43.0 8.1 242 246 A R H X S+ 0 0 53 -4,-2.0 4,-0.8 1,-0.2 -1,-0.3 0.909 109.5 45.0 -62.6 -36.2 35.2 43.1 8.4 243 247 A A H < S+ 0 0 13 -4,-1.3 4,-0.4 -3,-0.4 -2,-0.2 0.798 113.5 50.6 -71.4 -32.6 35.0 46.6 10.0 244 248 A Q H >X S+ 0 0 8 -4,-1.7 3,-1.7 1,-0.2 4,-0.5 0.896 105.0 57.4 -69.0 -44.7 32.2 45.5 12.4 245 249 A L H >< S+ 0 0 12 -4,-2.3 3,-0.8 1,-0.3 4,-0.5 0.778 97.6 62.6 -48.3 -46.1 34.2 42.4 13.4 246 250 A A T 3< S+ 0 0 87 -4,-0.8 -1,-0.3 1,-0.2 4,-0.2 0.689 107.4 41.2 -63.1 -24.5 37.0 44.6 14.6 247 251 A R T <> S+ 0 0 40 -3,-1.7 4,-1.3 -4,-0.4 -1,-0.2 0.420 91.1 95.1 -93.7 -7.5 34.9 46.3 17.3 248 252 A L H XX S+ 0 0 0 -3,-0.8 4,-2.3 -4,-0.5 3,-0.6 0.920 78.0 50.2 -55.4 -57.7 33.1 43.2 18.5 249 253 A D H 3> S+ 0 0 60 -4,-0.5 4,-1.3 1,-0.3 -1,-0.2 0.887 115.1 43.1 -48.1 -46.2 35.2 42.0 21.4 250 254 A E H 3> S+ 0 0 142 2,-0.2 4,-2.2 -4,-0.2 -1,-0.3 0.769 109.4 56.5 -74.9 -27.9 35.3 45.4 23.1 251 255 A Q H < S+ 0 0 0 -4,-2.8 3,-2.1 1,-0.2 6,-0.2 0.865 107.5 57.4 -69.5 -44.9 16.1 44.4 37.4 267 271 A G H 3< S+ 0 0 45 -4,-1.9 -1,-0.2 -5,-0.3 -2,-0.2 0.780 100.3 61.9 -64.1 -18.0 16.3 41.5 39.9 268 272 A A T 3< S+ 0 0 75 -4,-1.4 2,-0.4 -3,-0.2 -1,-0.3 0.474 83.4 91.5 -78.7 -14.4 15.5 44.1 42.6 269 273 A I S X S- 0 0 22 -3,-2.1 3,-0.9 3,-0.2 2,-0.3 -0.750 86.6-121.0 -88.3 128.6 12.1 44.8 41.0 270 274 A D T 3 S+ 0 0 152 -2,-0.4 3,-0.1 1,-0.2 -2,-0.1 -0.689 99.5 24.4 -69.6 144.6 9.5 42.6 42.6 271 275 A G T 3 S+ 0 0 47 -2,-0.3 2,-0.5 1,-0.2 -1,-0.2 -0.110 104.3 106.4 91.9 -25.1 7.8 40.5 39.9 272 276 A V < + 0 0 7 -3,-0.9 21,-0.2 -6,-0.2 -3,-0.2 -0.746 41.8 178.1-102.2 126.2 10.9 40.8 37.6 273 277 A V E -M 292 0G 76 19,-2.0 19,-2.3 -2,-0.5 3,-0.1 -0.822 19.2-145.5-127.2 105.1 13.5 38.1 36.9 274 278 A P E -M 291 0G 16 0, 0.0 17,-0.3 0, 0.0 15,-0.0 -0.022 45.3 -74.3 -59.6 153.0 16.4 38.9 34.4 275 279 A Q - 0 0 4 15,-3.2 -168,-0.3 1,-0.1 -169,-0.1 -0.328 61.4-113.8 -46.6 141.6 17.7 36.1 32.2 276 280 A G - 0 0 23 -170,-4.1 2,-0.1 1,-0.1 -1,-0.1 -0.209 26.2-129.1 -77.8 168.9 19.7 33.7 34.4 277 281 A G - 0 0 63 -143,-0.0 2,-0.3 -2,-0.0 -1,-0.1 -0.276 8.5-153.4-104.3-174.8 23.5 33.3 34.1 278 282 A D - 0 0 38 3,-0.2 3,-0.3 -2,-0.1 -143,-0.1 -0.842 9.7-150.3-164.8 119.2 25.7 30.2 33.7 279 283 A V S S+ 0 0 140 -2,-0.3 -114,-0.1 1,-0.2 -1,-0.1 0.789 95.1 65.1 -75.7 -25.6 29.3 30.3 34.9 280 284 A R S S+ 0 0 73 1,-0.2 -115,-3.5 -115,-0.1 2,-1.8 0.816 88.8 75.6 -56.6 -26.8 30.5 27.7 32.4 281 285 A A + 0 0 10 -3,-0.3 -3,-0.2 -117,-0.2 -117,-0.2 -0.581 67.1 177.4 -85.6 85.6 29.5 30.3 29.7 282 286 A D + 0 0 80 -2,-1.8 2,-0.4 1,-0.2 -1,-0.2 0.665 67.2 37.9 -69.6 -16.3 32.5 32.5 30.4 283 287 A R B -J 163 0D 63 -120,-1.6 -120,-2.7 -3,-0.1 2,-0.5 -0.940 67.6-172.7-142.5 110.0 31.7 35.1 27.7 284 288 A N - 0 0 15 -2,-0.4 -150,-0.2 -122,-0.2 -151,-0.1 -0.949 16.2-149.4 -95.5 123.5 28.1 36.0 27.1 285 289 A S - 0 0 0 -152,-1.6 -152,-0.2 -2,-0.5 -30,-0.1 0.788 21.9-138.3 -70.7 -21.6 27.7 38.2 24.1 286 290 A H + 0 0 2 -154,-0.4 -153,-0.2 2,-0.1 77,-0.1 0.930 39.0 163.0 67.8 48.5 24.8 40.0 25.4 287 291 A Y S S+ 0 0 16 -155,-0.9 73,-1.0 -129,-0.5 2,-0.3 0.822 72.4 16.3 -69.0 -38.8 22.7 40.1 22.2 288 292 A M E - N 0 359G 2 -156,-0.9 2,-0.8 71,-0.2 71,-0.2 -0.996 67.3-136.9-131.4 151.5 19.6 40.9 24.2 289 293 A A E - N 0 358G 0 69,-2.0 69,-1.9 -2,-0.3 2,-0.3 -0.921 44.5-175.4 -97.1 92.9 19.0 42.2 27.8 290 294 A M E + N 0 357G 0 -2,-0.8 -15,-3.2 67,-0.2 2,-0.3 -0.765 16.0 171.6-101.5 141.8 16.0 39.9 28.6 291 295 A F E -MN 274 356G 0 65,-3.2 65,-2.6 -2,-0.3 2,-0.2 -0.994 20.0-140.0-146.9 146.5 13.7 39.6 31.6 292 296 A R E -MN 273 355G 27 -19,-2.3 -19,-2.0 -2,-0.3 63,-0.2 -0.479 4.6-162.3 -96.9 157.2 10.5 37.7 32.7 293 297 A I > - 0 0 6 61,-0.8 3,-2.0 -21,-0.2 -21,-0.2 -0.727 33.7-142.7-133.6 65.2 7.6 39.0 34.7 294 298 A P T 3 S+ 0 0 68 0, 0.0 3,-0.1 0, 0.0 57,-0.0 -0.169 78.2 28.3 -43.1 137.8 6.2 35.5 35.6 295 299 A G T 3 S+ 0 0 70 1,-0.3 2,-0.2 55,-0.0 59,-0.0 0.234 85.6 129.3 93.4 -18.3 2.4 35.3 35.7 296 300 A L < - 0 0 15 -3,-2.0 -1,-0.3 58,-0.1 2,-0.3 -0.456 55.8-132.0 -66.0 138.4 1.8 38.0 33.1 297 301 A T >> - 0 0 73 -2,-0.2 4,-2.7 1,-0.1 3,-0.9 -0.689 31.5-103.8 -73.7 170.7 -0.5 37.0 30.2 298 302 A E H 3> S+ 0 0 41 1,-0.3 4,-4.5 -2,-0.3 5,-0.3 0.899 122.5 55.5 -54.0 -46.4 0.8 38.0 26.7 299 303 A E H 3> S+ 0 0 132 1,-0.2 4,-1.6 2,-0.2 -1,-0.3 0.853 109.5 44.1 -61.9 -43.3 -1.6 40.9 26.6 300 304 A R H <> S+ 0 0 114 -3,-0.9 4,-2.1 2,-0.2 -1,-0.2 0.906 115.7 48.2 -66.7 -46.7 -0.3 42.3 29.8 301 305 A R H X S+ 0 0 9 -4,-2.7 4,-3.5 52,-0.4 5,-0.2 0.955 113.4 48.5 -55.8 -44.9 3.4 41.7 28.7 302 306 A N H X S+ 0 0 57 -4,-4.5 4,-2.4 1,-0.3 5,-0.2 0.923 111.7 49.7 -59.8 -36.7 2.6 43.3 25.3 303 307 A A H X S+ 0 0 38 -4,-1.6 4,-1.7 -5,-0.3 -1,-0.3 0.892 109.8 50.3 -71.3 -37.3 1.0 46.3 27.1 304 308 A L H >X S+ 0 0 4 -4,-2.1 4,-2.9 2,-0.2 3,-0.6 0.980 107.4 54.2 -67.2 -48.0 4.0 46.7 29.3 305 309 A V H 3X S+ 0 0 12 -4,-3.5 4,-3.2 1,-0.3 5,-0.3 0.956 108.7 50.1 -45.3 -52.1 6.3 46.6 26.2 306 310 A D H 3X S+ 0 0 84 -4,-2.4 4,-2.1 1,-0.2 -1,-0.3 0.876 109.6 49.1 -56.0 -42.2 4.2 49.4 24.8 307 311 A R H <>S+ 0 0 0 -4,-2.9 5,-1.9 2,-0.2 3,-1.0 0.989 110.3 48.0 -64.2 -41.5 8.2 50.9 28.0 309 313 A V H ><5S+ 0 0 78 -4,-3.2 3,-1.7 1,-0.3 -1,-0.2 0.894 108.9 54.8 -61.6 -40.0 8.5 52.1 24.3 310 314 A E H 3<5S+ 0 0 127 -4,-2.1 -1,-0.3 -5,-0.3 -2,-0.2 0.842 103.9 55.5 -63.0 -27.3 6.5 55.1 25.2 311 315 A A T <<5S- 0 0 38 -4,-1.4 -1,-0.3 -3,-1.0 -2,-0.2 0.441 130.2 -91.8 -88.1 6.3 8.9 55.9 28.0 312 316 A G T < 5S+ 0 0 34 -3,-1.7 -3,-0.2 -4,-0.4 -2,-0.1 0.609 82.0 132.8 99.8 11.9 11.9 56.0 25.6 313 317 A L < - 0 0 5 -5,-1.9 2,-2.3 -6,-0.1 -1,-0.3 -0.813 59.9-131.2-102.0 146.6 13.1 52.4 25.8 314 318 A P + 0 0 18 0, 0.0 45,-2.1 0, 0.0 2,-0.3 -0.371 54.8 156.2 -85.0 71.7 13.9 50.0 22.9 315 319 A A E +O 358 0G 4 -2,-2.3 2,-0.3 43,-0.2 43,-0.2 -0.712 18.6 178.5-113.2 143.9 11.8 47.2 24.4 316 320 A F E -O 357 0G 83 41,-2.3 41,-2.3 -2,-0.3 2,-0.1 -0.997 34.4-103.1-132.3 155.5 10.2 44.3 22.7 317 321 A A E -O 356 0G 38 -2,-0.3 39,-0.2 39,-0.2 3,-0.1 -0.503 48.2-119.2 -72.3 151.2 8.1 41.2 23.3 318 322 A A - 0 0 9 37,-1.8 -1,-0.1 33,-0.2 37,-0.0 -0.256 48.5 -53.4 -89.9 174.2 10.3 38.1 23.2 319 323 A F - 0 0 30 1,-0.1 2,-0.3 -2,-0.1 -1,-0.2 -0.005 53.6-120.1 -50.4 150.3 9.9 35.2 20.8 320 324 A R - 0 0 105 -237,-0.2 -237,-0.5 -3,-0.1 -1,-0.1 -0.715 39.6 -93.0 -85.9 145.6 6.6 33.5 20.4 321 325 A A > - 0 0 0 -2,-0.3 3,-2.7 27,-0.2 -239,-0.2 -0.398 38.0-132.1 -54.1 127.6 6.6 29.7 21.2 322 326 A I G > S+ 0 0 0 -241,-2.5 3,-1.6 1,-0.3 6,-0.4 0.831 105.7 60.6 -61.9 -25.3 7.2 28.3 17.7 323 327 A Y G 3 S+ 0 0 1 1,-0.3 -1,-0.3 -242,-0.2 -2,-0.1 0.511 99.4 59.9 -75.1 -6.4 4.3 25.8 18.1 324 328 A R G < S+ 0 0 74 -3,-2.7 2,-0.4 -4,-0.0 -1,-0.3 0.209 87.1 88.8-105.3 19.2 2.0 28.9 18.4 325 329 A T S <> S- 0 0 29 -3,-1.6 4,-0.8 1,-0.1 3,-0.3 -0.904 74.4-137.7-108.9 143.3 2.9 30.4 15.0 326 330 A D H >> S+ 0 0 147 -2,-0.4 4,-1.3 1,-0.2 3,-0.8 0.892 101.7 66.5 -59.2 -39.1 0.8 29.4 12.0 327 331 A A H >> S+ 0 0 48 1,-0.3 3,-0.7 2,-0.2 4,-0.6 0.909 94.9 56.4 -46.3 -46.8 4.0 29.2 10.0 328 332 A F H 34 S+ 0 0 7 -6,-0.4 3,-0.3 -3,-0.3 -1,-0.3 0.894 107.6 48.0 -59.0 -39.0 5.2 26.2 12.0 329 333 A W H << S+ 0 0 72 -3,-0.8 4,-0.3 -4,-0.8 -1,-0.2 0.755 90.7 83.1 -80.4 -10.1 2.1 24.2 11.2 330 334 A E H << S+ 0 0 160 -4,-1.3 2,-0.3 -3,-0.7 -1,-0.2 0.835 104.9 0.1 -61.3 -48.1 2.2 24.9 7.4 331 335 A L S < S+ 0 0 89 -4,-0.6 -1,-0.1 -3,-0.3 -239,-0.1 -0.978 125.7 15.5-140.4 155.6 4.7 22.1 6.5 332 336 A G S S+ 0 0 31 -2,-0.3 -234,-1.1 1,-0.2 -2,-0.1 0.688 76.6 167.6 57.0 22.9 6.7 19.4 8.3 333 337 A A - 0 0 35 -4,-0.3 -1,-0.2 -236,-0.2 2,-0.1 -0.336 38.8-110.6 -63.3 146.7 4.6 19.7 11.5 334 338 A P - 0 0 13 0, 0.0 -1,-0.1 0, 0.0 -235,-0.0 -0.474 27.5-111.9 -75.0 153.7 5.0 16.9 14.1 335 339 A D S S+ 0 0 171 -2,-0.1 -2,-0.1 2,-0.0 0, 0.0 0.794 88.7 97.3 -60.7 -29.5 2.0 14.5 14.5 336 340 A E S S- 0 0 62 1,-0.1 2,-0.2 2,-0.1 3,-0.0 0.092 77.7-113.6 -49.6 169.8 1.2 15.9 18.1 337 341 A S > - 0 0 61 1,-0.1 4,-1.7 0, 0.0 5,-0.1 -0.482 31.7-100.5 -93.9 177.3 -1.5 18.5 18.7 338 342 A V H > S+ 0 0 49 1,-0.2 4,-2.9 2,-0.2 5,-0.2 0.889 123.6 47.4 -67.7 -42.7 -0.7 22.1 19.9 339 343 A D H > S+ 0 0 102 1,-0.2 4,-3.0 2,-0.2 -1,-0.2 0.850 108.0 56.4 -69.5 -31.1 -1.7 21.3 23.5 340 344 A A H > S+ 0 0 22 2,-0.2 4,-1.3 1,-0.2 -1,-0.2 0.893 110.9 43.2 -66.4 -42.0 0.4 18.1 23.4 341 345 A I H >X S+ 0 0 0 -4,-1.7 4,-0.6 2,-0.2 3,-0.5 0.966 115.0 50.2 -67.6 -48.8 3.5 20.2 22.4 342 346 A A H >< S+ 0 0 11 -4,-2.9 3,-1.9 1,-0.2 -2,-0.2 0.913 103.7 60.0 -54.3 -40.7 2.6 22.8 25.0 343 347 A R H 3< S+ 0 0 176 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.895 111.3 39.4 -57.7 -40.6 2.2 20.2 27.7 344 348 A R H << S+ 0 0 85 -4,-1.3 -242,-0.5 -3,-0.5 -1,-0.3 0.373 115.0 56.5 -90.9 13.4 5.8 19.1 27.3 345 349 A C S+ 0 0 74 0, 0.0 4,-1.5 0, 0.0 5,-0.2 0.843 73.3 50.1 -65.5 -34.1 5.9 24.5 30.0 347 351 A N H >> S+ 0 0 54 2,-0.2 4,-2.9 -244,-0.1 3,-0.6 0.992 113.9 44.4 -70.5 -48.0 8.8 26.8 30.3 348 352 A T H 3> S+ 0 0 0 1,-0.2 4,-3.9 2,-0.2 5,-0.3 0.973 109.4 59.0 -54.6 -47.4 8.5 27.9 26.6 349 353 A D H 3X S+ 0 0 45 -4,-2.9 4,-0.7 1,-0.3 -1,-0.2 0.841 114.6 34.9 -51.4 -35.1 4.8 28.2 27.1 350 354 A A H -N 288 0G 27 -45,-2.1 3,-2.3 -2,-0.4 4,-0.3 -0.435 33.1-120.4 -60.3 138.2 18.0 46.1 22.5 360 364 A H G > S+ 0 0 1 -73,-1.0 3,-1.0 1,-0.3 4,-0.2 0.646 107.0 77.8 -55.4 -9.8 21.7 45.3 23.2 361 365 A R G > S+ 0 0 63 1,-0.3 3,-0.6 2,-0.2 -1,-0.3 0.691 83.2 64.9 -70.7 -23.7 22.5 49.0 22.4 362 366 A V G X S+ 0 0 0 -3,-2.3 3,-1.6 1,-0.2 -1,-0.3 0.856 94.1 60.7 -65.1 -34.7 21.1 49.8 25.9 363 367 A L G < S+ 0 0 0 -3,-1.0 -105,-0.4 1,-0.3 -1,-0.2 0.357 98.3 57.1 -75.0 2.1 24.1 47.7 27.3 364 368 A L G < S+ 0 0 29 -3,-0.6 -1,-0.3 -4,-0.2 -2,-0.2 0.376 90.6 99.2-104.6 -14.8 26.5 50.1 25.7 365 369 A A S < S- 0 0 4 -3,-1.6 2,-0.1 1,-0.1 -360,-0.1 -0.230 83.0 -88.1 -77.6 175.6 25.1 53.1 27.5 366 370 A G > - 0 0 27 1,-0.1 4,-1.6 -108,-0.0 3,-0.3 -0.373 37.1-106.4 -71.0 164.6 26.4 54.7 30.6 367 371 A E H >> S+ 0 0 87 1,-0.2 4,-1.7 2,-0.2 3,-0.5 0.950 117.5 59.7 -58.7 -44.6 25.5 53.6 34.2 368 372 A P H 3> S+ 0 0 92 0, 0.0 4,-2.5 0, 0.0 3,-0.4 0.907 105.4 49.5 -49.9 -45.1 23.2 56.6 34.8 369 373 A E H 3> S+ 0 0 59 -3,-0.3 4,-2.3 1,-0.2 -2,-0.2 0.870 107.5 53.4 -70.0 -33.4 21.1 55.6 31.8 370 374 A L H X S+ 0 0 91 -4,-2.7 4,-1.5 2,-0.2 3,-0.8 0.981 115.1 47.2 -59.5 -55.0 7.2 52.1 37.6 380 384 A A H 3X S+ 0 0 10 -4,-2.5 4,-0.7 1,-0.3 -1,-0.2 0.867 108.3 54.0 -59.8 -38.3 5.7 50.4 34.5 381 385 A V H >< S+ 0 0 18 -4,-2.3 3,-0.7 -5,-0.2 -1,-0.3 0.881 101.3 61.8 -69.3 -19.3 5.8 46.9 36.1 382 386 A G H << S+ 0 0 68 -4,-1.3 -2,-0.2 -3,-0.8 -1,-0.2 0.945 111.2 39.0 -70.9 -39.8 3.9 48.3 39.1 383 387 A R H 3< 0 0 192 -4,-1.5 -1,-0.3 -79,-0.0 -2,-0.2 0.489 360.0 360.0 -87.9 -2.2 1.0 49.1 36.7 384 388 A A << 0 0 35 -4,-0.7 -83,-0.1 -3,-0.7 -84,-0.1 -0.127 360.0 360.0 -71.9 360.0 1.2 46.0 34.5