==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=22-FEB-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 04-OCT-12 4BD1 . COMPND 2 MOLECULE: TOHO-1 BETA-LACTAMASE; . SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI BL21; . AUTHOR S.J.TOMANICEK,K.L.WEISS,R.F.STANDAERT,A.OSTERMANN,T.E.SCHRAD . 261 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11133.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 184 70.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 40 15.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 6 2.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 14.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 82 31.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 2 1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 1 1 0 1 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 27 A N 0 0 102 0, 0.0 5,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 131.8 -9.9 0.7 9.5 2 28 A S > - 0 0 64 1,-0.1 4,-1.8 3,-0.1 5,-0.1 -0.043 360.0-107.3 -55.3 166.6 -10.8 2.7 6.4 3 29 A V H > S+ 0 0 37 2,-0.2 4,-1.8 1,-0.2 5,-0.2 0.852 123.7 56.3 -59.2 -37.5 -13.7 5.3 6.5 4 30 A Q H > S+ 0 0 89 1,-0.2 4,-2.1 2,-0.2 -1,-0.2 0.937 106.7 47.8 -63.1 -46.3 -15.7 2.7 4.4 5 31 A Q H > S+ 0 0 134 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.890 110.7 52.1 -59.2 -40.1 -15.2 -0.0 7.1 6 32 A Q H X S+ 0 0 72 -4,-1.8 4,-1.8 2,-0.2 -1,-0.2 0.834 109.9 46.6 -68.5 -37.5 -16.2 2.3 9.9 7 33 A L H X S+ 0 0 0 -4,-1.8 4,-3.6 2,-0.2 -1,-0.2 0.900 111.7 52.8 -70.7 -40.8 -19.5 3.4 8.3 8 34 A E H X S+ 0 0 114 -4,-2.1 4,-2.8 1,-0.2 -2,-0.2 0.941 111.5 45.5 -60.1 -43.4 -20.3 -0.2 7.5 9 35 A A H X S+ 0 0 56 -4,-2.3 4,-1.9 2,-0.2 5,-0.2 0.868 112.9 50.7 -67.8 -38.9 -19.7 -1.2 11.0 10 36 A L H X S+ 0 0 36 -4,-1.8 4,-1.9 2,-0.2 -2,-0.2 0.965 112.2 47.3 -62.6 -46.4 -21.8 1.8 12.2 11 37 A E H X>S+ 0 0 10 -4,-3.6 4,-1.3 1,-0.2 5,-1.0 0.948 111.0 51.3 -59.7 -49.1 -24.6 0.8 9.9 12 38 A K H ><5S+ 0 0 176 -4,-2.8 3,-0.7 1,-0.2 -1,-0.2 0.907 112.5 44.0 -55.6 -49.8 -24.6 -2.9 10.9 13 39 A S H 3<5S+ 0 0 108 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.828 109.3 57.5 -64.2 -36.4 -24.7 -2.3 14.7 14 40 A S H 3<5S- 0 0 11 -4,-1.9 -1,-0.3 -5,-0.2 -2,-0.2 0.781 100.1-139.5 -68.1 -26.7 -27.4 0.4 14.2 15 41 A G T <<5 + 0 0 46 -4,-1.3 -3,-0.2 -3,-0.7 2,-0.2 0.670 68.2 88.1 75.9 16.0 -29.6 -2.2 12.4 16 42 A G S >> -AB 230 29A 32 5,-2.3 4,-1.5 -2,-0.5 3,-0.9 -0.839 6.8-160.7 -95.2 106.2 -14.8 18.4 -0.0 25 51 A T T 345S+ 0 0 30 204,-1.6 -1,-0.1 -2,-0.8 205,-0.1 0.579 79.0 77.9 -72.2 -7.5 -15.0 21.6 -2.1 26 52 A A T 345S- 0 0 66 203,-0.3 -1,-0.2 202,-0.2 204,-0.1 0.942 124.4 -3.2 -61.5 -43.2 -11.3 22.1 -1.9 27 53 A D T <45S- 0 0 101 -3,-0.9 -2,-0.2 2,-0.1 -1,-0.2 0.265 96.1-112.5-133.6 11.0 -10.6 19.5 -4.5 28 54 A N T <5 + 0 0 96 -4,-1.5 2,-0.2 1,-0.2 -3,-0.2 0.770 63.6 152.5 54.3 26.3 -14.0 18.1 -5.3 29 55 A S E < -B 24 0A 45 -5,-0.8 -5,-2.3 2,-0.0 2,-0.3 -0.539 30.1-148.1 -76.6 159.5 -13.1 14.7 -3.8 30 56 A Q E -B 23 0A 78 -7,-0.2 2,-0.5 -2,-0.2 -7,-0.2 -0.945 19.3-155.3-135.8 143.9 -16.0 12.7 -2.3 31 57 A I E -B 22 0A 42 -9,-2.3 -9,-2.5 -2,-0.3 2,-0.4 -0.991 30.2-177.1-114.7 119.1 -16.7 10.2 0.5 32 59 A L E +B 21 0A 68 -2,-0.5 2,-0.3 -11,-0.2 -11,-0.2 -0.920 20.9 174.3-122.3 138.0 -19.7 8.1 -0.5 33 60 A Y E S-B 20 0A 16 -13,-2.2 -13,-2.4 -2,-0.4 -2,-0.0 -0.874 85.0 -25.5-141.7 114.7 -21.6 5.4 1.3 34 61 A R S > S+ 0 0 119 -2,-0.3 3,-1.4 -15,-0.2 123,-0.1 0.873 89.7 154.0 49.2 38.8 -24.8 4.0 -0.4 35 62 A A T 3 + 0 0 3 1,-0.3 122,-2.2 121,-0.1 123,-0.5 0.707 61.3 53.5 -78.6 -13.4 -24.8 7.4 -2.0 36 63 A D T 3 S+ 0 0 123 120,-0.1 2,-0.3 119,-0.1 -1,-0.3 0.309 89.2 103.7 -97.3 8.1 -26.8 6.4 -5.1 37 64 A E S < S- 0 0 54 -3,-1.4 2,-0.2 1,-0.0 120,-0.1 -0.742 74.7-115.2 -94.3 146.0 -29.6 4.8 -3.1 38 65 A R + 0 0 95 -2,-0.3 2,-0.3 117,-0.2 117,-0.2 -0.449 34.1 178.5 -75.3 140.4 -32.9 6.5 -2.6 39 66 A F E -E 154 0B 0 115,-3.0 115,-1.8 -2,-0.2 2,-0.3 -0.982 38.1 -99.7-135.7 152.2 -34.1 7.7 0.8 40 67 A A E -E 153 0B 6 -2,-0.3 113,-0.3 113,-0.2 112,-0.1 -0.563 29.2-152.2 -69.1 132.2 -37.2 9.5 2.0 41 68 A M > + 0 0 0 111,-2.2 3,-1.8 -2,-0.3 -1,-0.1 0.832 23.5 174.9 -76.1 -32.1 -36.3 13.2 2.4 42 69 A C G > S- 0 0 0 110,-0.6 3,-1.8 100,-0.5 -1,-0.2 -0.329 73.1 -8.9 49.8-138.0 -38.8 14.0 5.0 43 70 A S G > S+ 0 0 8 1,-0.3 3,-1.5 167,-0.3 4,-0.3 0.546 121.1 81.0 -69.0 -7.3 -38.3 17.6 6.2 44 71 A T G X S+ 0 0 0 -3,-1.8 3,-1.0 1,-0.3 4,-0.4 0.751 80.5 69.1 -70.3 -14.5 -35.0 18.0 4.2 45 72 A S G <> S+ 0 0 0 -3,-1.8 4,-1.2 1,-0.2 3,-0.4 0.572 77.8 81.2 -74.8 -15.5 -37.2 18.6 1.1 46 73 A K H <> S+ 0 0 0 -3,-1.5 4,-2.4 1,-0.2 -1,-0.2 0.824 82.4 63.0 -60.7 -28.9 -38.2 22.0 2.7 47 74 A V H <> S+ 0 0 0 -3,-1.0 4,-2.5 -4,-0.3 -1,-0.2 0.894 101.9 50.3 -63.0 -36.4 -34.9 23.5 1.4 48 75 A M H > S+ 0 0 0 -3,-0.4 4,-1.6 -4,-0.4 -1,-0.2 0.834 110.9 47.9 -72.6 -37.4 -36.0 22.9 -2.2 49 76 A A H X S+ 0 0 0 -4,-1.2 4,-1.3 2,-0.2 -2,-0.2 0.895 114.5 45.6 -70.0 -43.0 -39.4 24.5 -1.7 50 77 A A H X S+ 0 0 1 -4,-2.4 4,-1.5 1,-0.2 -2,-0.2 0.895 112.9 51.9 -65.1 -43.3 -37.7 27.6 0.1 51 78 A A H X S+ 0 0 0 -4,-2.5 4,-2.0 -5,-0.2 -2,-0.2 0.852 104.2 56.6 -62.4 -35.4 -35.1 27.7 -2.7 52 79 A A H X S+ 0 0 2 -4,-1.6 4,-1.9 1,-0.2 -1,-0.2 0.866 108.0 47.3 -65.3 -37.6 -37.8 27.6 -5.4 53 80 A V H X S+ 0 0 1 -4,-1.3 4,-1.7 2,-0.2 -1,-0.2 0.782 109.4 53.8 -71.1 -36.4 -39.4 30.8 -4.0 54 81 A L H X S+ 0 0 0 -4,-1.5 4,-0.6 2,-0.2 -2,-0.2 0.906 106.6 52.7 -64.8 -38.8 -36.1 32.4 -3.7 55 82 A K H >< S+ 0 0 63 -4,-2.0 3,-1.7 1,-0.2 4,-0.4 0.946 107.5 50.9 -61.2 -44.8 -35.5 31.7 -7.4 56 83 A Q H >X S+ 0 0 84 -4,-1.9 3,-1.7 1,-0.3 4,-0.9 0.874 102.6 61.4 -56.8 -40.1 -38.8 33.3 -8.2 57 84 A S H 3< S+ 0 0 5 -4,-1.7 -1,-0.3 1,-0.3 -2,-0.2 0.684 87.1 74.9 -66.7 -15.1 -37.8 36.3 -6.2 58 85 A E T << S+ 0 0 61 -3,-1.7 -1,-0.3 -4,-0.6 -2,-0.2 0.743 110.1 27.7 -65.6 -25.1 -34.8 36.9 -8.6 59 86 A S T <4 S+ 0 0 122 -3,-1.7 2,-0.4 -4,-0.4 -1,-0.2 0.460 120.4 58.8-116.9 -3.7 -37.1 38.3 -11.2 60 87 A D >< - 0 0 66 -4,-0.9 3,-1.9 1,-0.1 4,-0.4 -0.763 59.4-172.9-133.3 97.0 -39.9 39.6 -8.9 61 88 A K T 3 S+ 0 0 174 -2,-0.4 4,-0.1 1,-0.3 -1,-0.1 0.592 84.7 48.9 -70.7 -11.6 -38.7 42.2 -6.4 62 89 A H T > S+ 0 0 131 1,-0.1 3,-1.0 2,-0.1 4,-0.3 0.572 87.3 93.0 -98.2 -10.0 -42.0 42.4 -4.4 63 90 A L G X S+ 0 0 15 -3,-1.9 3,-2.5 1,-0.2 29,-0.4 0.885 76.8 52.0 -56.1 -54.1 -42.4 38.7 -4.0 64 91 A L G 3 S+ 0 0 26 -4,-0.4 29,-2.6 1,-0.3 30,-0.4 0.684 110.8 51.6 -61.6 -21.2 -40.8 37.9 -0.6 65 92 A N G < S+ 0 0 97 -3,-1.0 -1,-0.3 27,-0.2 -2,-0.2 0.413 78.5 122.8 -95.0 -4.6 -42.8 40.6 1.0 66 93 A Q < - 0 0 95 -3,-2.5 26,-1.6 -4,-0.3 2,-0.4 -0.350 62.3-129.6 -54.0 131.5 -46.1 39.3 -0.4 67 94 A R E -F 91 0C 162 24,-0.2 2,-0.4 25,-0.1 24,-0.3 -0.756 19.7-162.2 -91.2 143.3 -48.4 38.6 2.6 68 95 A V E -F 90 0C 30 22,-2.4 22,-1.8 -2,-0.4 2,-0.5 -0.974 20.6-120.6-123.1 135.4 -50.3 35.2 3.0 69 96 A E E -F 89 0C 105 -2,-0.4 2,-0.6 20,-0.2 20,-0.2 -0.653 18.7-154.5 -82.5 128.8 -53.3 34.7 5.3 70 97 A I + 0 0 1 18,-1.9 17,-3.7 -2,-0.5 18,-0.4 -0.869 18.8 179.2-102.6 117.6 -53.0 32.0 8.1 71 98 A K >> - 0 0 95 -2,-0.6 3,-1.2 15,-0.2 4,-0.7 -0.751 43.7-106.6-112.2 161.2 -56.3 30.6 9.2 72 99 A K G >4 S+ 0 0 134 -2,-0.3 3,-0.7 1,-0.2 -1,-0.1 0.829 119.7 56.6 -53.0 -32.8 -57.1 27.9 11.7 73 100 A S G 34 S+ 0 0 103 1,-0.2 -1,-0.2 -3,-0.0 -3,-0.0 0.732 94.5 65.9 -76.8 -17.9 -57.9 25.5 8.9 74 101 A D G <4 S+ 0 0 37 -3,-1.2 -1,-0.2 8,-0.1 -2,-0.2 0.800 79.6 105.2 -70.7 -23.5 -54.4 25.9 7.3 75 102 A L << + 0 0 51 -4,-0.7 3,-0.1 -3,-0.7 2,-0.1 -0.293 44.0 172.0 -68.4 130.5 -52.8 24.3 10.3 76 103 A V - 0 0 56 1,-0.3 2,-0.3 -2,-0.1 3,-0.2 0.121 52.8 -44.6-103.8-134.3 -51.6 20.7 9.9 77 104 A N S S+ 0 0 91 1,-0.2 -1,-0.3 -2,-0.1 28,-0.3 -0.716 117.7 11.8-101.8 145.0 -49.6 18.9 12.4 78 105 A Y + 0 0 117 -2,-0.3 27,-2.4 1,-0.1 28,-0.4 0.936 63.3 163.3 47.0 96.7 -46.6 20.7 14.1 79 106 A N > + 0 0 20 25,-0.2 4,-2.1 -3,-0.2 5,-0.3 -0.552 1.7 164.6-135.8 61.1 -46.8 24.5 13.3 80 107 A P T 4 S+ 0 0 24 0, 0.0 4,-0.2 0, 0.0 -1,-0.1 0.852 82.9 25.6 -60.6 -30.9 -44.5 26.1 15.8 81 108 A I T 4 S+ 0 0 42 2,-0.1 3,-0.3 1,-0.1 -2,-0.1 0.824 120.3 53.2 -96.7 -43.5 -44.3 29.4 13.9 82 109 A A T >4 S+ 0 0 0 1,-0.2 3,-2.2 2,-0.2 -1,-0.1 0.816 99.7 61.9 -63.4 -33.7 -47.6 29.4 12.0 83 110 A E G >< S+ 0 0 108 -4,-2.1 3,-1.1 1,-0.3 -1,-0.2 0.870 96.7 62.4 -64.5 -27.1 -49.8 28.8 15.0 84 111 A K G 3 S+ 0 0 156 -3,-0.3 -1,-0.3 -5,-0.3 -2,-0.2 0.523 107.7 44.3 -72.6 -0.5 -48.4 32.2 16.3 85 112 A H G X S+ 0 0 60 -3,-2.2 3,-1.9 3,-0.1 -15,-0.4 0.172 70.3 142.7-133.8 19.9 -50.1 33.8 13.3 86 113 A V T < S+ 0 0 30 -3,-1.1 -15,-0.2 1,-0.3 3,-0.1 -0.488 81.1 16.8 -62.5 131.7 -53.6 32.4 12.9 87 114 A N T 3 S+ 0 0 144 -17,-3.7 -1,-0.3 1,-0.4 -16,-0.1 0.345 123.5 73.2 80.6 -4.6 -56.0 35.2 11.8 88 115 A G S < S- 0 0 27 -3,-1.9 -18,-1.9 -18,-0.4 -1,-0.4 -0.151 82.4-105.6-111.6-152.4 -53.0 37.2 10.8 89 116 A T E -F 69 0C 71 -20,-0.2 2,-0.3 -3,-0.1 -20,-0.2 -0.931 14.1-157.8-137.0 163.0 -50.5 37.0 7.9 90 117 A M E -F 68 0C 1 -22,-1.8 -22,-2.4 -2,-0.3 2,-0.1 -0.972 26.0-122.9-136.2 141.3 -46.9 35.9 7.2 91 118 A T E > -F 67 0C 17 -2,-0.3 4,-1.9 -24,-0.3 -24,-0.2 -0.430 31.1-106.8 -75.0 164.3 -44.8 37.2 4.2 92 119 A L H > S+ 0 0 0 -26,-1.6 4,-2.4 -29,-0.4 -27,-0.2 0.869 123.2 55.5 -59.3 -36.2 -43.4 34.5 1.9 93 120 A A H > S+ 0 0 20 -29,-2.6 4,-2.4 -27,-0.2 -1,-0.2 0.904 106.4 49.3 -60.9 -41.9 -39.9 35.4 3.4 94 121 A E H > S+ 0 0 85 -30,-0.4 4,-2.1 2,-0.2 -1,-0.2 0.848 111.0 50.2 -64.8 -36.8 -41.2 34.6 6.9 95 122 A L H X S+ 0 0 0 -4,-1.9 4,-2.4 2,-0.2 5,-0.2 0.904 108.5 51.9 -67.0 -41.2 -42.6 31.3 5.7 96 123 A G H X S+ 0 0 1 -4,-2.4 4,-1.7 1,-0.2 -2,-0.2 0.927 113.3 45.7 -58.8 -50.1 -39.3 30.4 4.1 97 124 A A H X S+ 0 0 22 -4,-2.4 4,-2.7 2,-0.2 5,-0.4 0.855 113.2 47.6 -58.9 -46.6 -37.6 31.1 7.4 98 125 A A H X>S+ 0 0 0 -4,-2.1 4,-2.3 2,-0.2 6,-1.3 0.945 110.6 51.8 -67.1 -46.3 -40.1 29.3 9.6 99 126 A A H <5S+ 0 0 0 -4,-2.4 4,-0.5 4,-0.3 -2,-0.2 0.880 119.9 34.7 -54.0 -42.6 -40.1 26.2 7.3 100 127 A L H <5S+ 0 0 0 -4,-1.7 108,-0.2 -5,-0.2 -2,-0.2 0.903 124.5 37.2 -86.4 -44.9 -36.3 25.9 7.4 101 128 A Q H <5S+ 0 0 39 -4,-2.7 87,-2.1 -5,-0.2 88,-0.3 0.754 135.9 20.4 -83.8 -26.4 -35.3 27.1 10.9 102 129 A Y T <5S- 0 0 74 -4,-2.3 -3,-0.2 -5,-0.4 -2,-0.2 0.448 95.5-125.9-120.3 -3.1 -38.2 25.5 12.7 103 130 A S < - 0 0 10 -5,-0.6 -4,-0.3 -4,-0.5 2,-0.2 0.856 38.9-172.1 59.0 35.9 -39.3 22.9 10.2 104 131 A D > - 0 0 0 -6,-1.3 4,-1.5 1,-0.1 -25,-0.2 -0.418 16.8-157.4 -64.6 124.2 -42.8 24.3 10.3 105 132 A N H > S+ 0 0 13 -27,-2.4 4,-2.5 -28,-0.3 34,-0.2 0.859 91.4 52.4 -76.8 -33.4 -45.2 22.1 8.4 106 133 A T H > S+ 0 0 1 -28,-0.4 4,-2.6 2,-0.2 5,-0.2 0.921 108.7 52.2 -64.3 -43.3 -47.9 24.7 7.8 107 134 A A H > S+ 0 0 0 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.908 108.6 50.8 -59.3 -43.4 -45.1 27.0 6.3 108 135 A M H X S+ 0 0 0 -4,-1.5 4,-2.4 1,-0.2 3,-0.3 0.988 110.7 48.4 -58.7 -49.0 -44.0 24.2 4.0 109 136 A N H X S+ 0 0 31 -4,-2.5 4,-2.1 1,-0.3 -2,-0.2 0.871 109.2 53.0 -63.4 -34.7 -47.5 23.6 2.8 110 137 A K H X S+ 0 0 33 -4,-2.6 4,-2.4 1,-0.2 -1,-0.3 0.913 109.4 48.7 -63.9 -41.6 -48.1 27.3 2.2 111 138 A L H X S+ 0 0 0 -4,-2.1 4,-1.7 -3,-0.3 -2,-0.2 0.891 111.3 49.1 -65.4 -42.3 -44.9 27.5 0.0 112 139 A I H X>S+ 0 0 3 -4,-2.4 5,-2.4 2,-0.2 4,-0.8 0.892 111.1 50.5 -63.0 -42.0 -45.9 24.5 -2.0 113 140 A A H ><5S+ 0 0 68 -4,-2.1 3,-0.8 -5,-0.3 -2,-0.2 0.911 108.3 52.2 -63.4 -43.4 -49.4 25.9 -2.6 114 141 A H H 3<5S+ 0 0 46 -4,-2.4 -1,-0.2 1,-0.2 -2,-0.2 0.872 110.1 49.6 -58.4 -41.3 -47.9 29.3 -3.7 115 142 A L H 3<5S- 0 0 21 -4,-1.7 -1,-0.2 -5,-0.1 -2,-0.2 0.607 122.7-104.7 -74.5 -17.5 -45.7 27.4 -6.2 116 143 A G T <<5S- 0 0 46 -3,-0.8 -3,-0.2 -4,-0.8 3,-0.2 0.662 72.3 -42.1 101.1 13.9 -48.7 25.4 -7.6 117 144 A G S >> S+ 0 0 20 0, 0.0 4,-1.6 0, 0.0 3,-0.4 0.773 123.6 65.0 -55.9 -36.0 -45.4 19.3 -5.3 119 146 A D H 3> S+ 0 0 92 1,-0.2 4,-2.0 2,-0.2 -2,-0.1 0.775 95.8 57.1 -61.0 -27.3 -44.7 18.8 -9.1 120 147 A K H <> S+ 0 0 96 -3,-1.8 4,-1.9 2,-0.2 -1,-0.2 0.775 104.4 51.6 -72.7 -32.7 -43.5 22.5 -9.4 121 148 A V H X S+ 0 0 0 -4,-0.7 4,-2.0 -3,-0.4 -2,-0.2 0.886 109.4 51.7 -65.3 -42.7 -40.9 21.9 -6.7 122 149 A T H X S+ 0 0 32 -4,-1.6 4,-1.8 1,-0.2 -2,-0.2 0.928 109.2 49.1 -60.2 -46.4 -39.8 18.8 -8.8 123 150 A A H X S+ 0 0 54 -4,-2.0 4,-2.1 1,-0.2 -1,-0.2 0.870 108.0 54.2 -61.2 -39.6 -39.5 21.0 -11.9 124 151 A F H X S+ 0 0 17 -4,-1.9 4,-0.6 2,-0.2 -1,-0.2 0.889 108.4 49.5 -57.3 -45.8 -37.4 23.6 -10.1 125 152 A A H ><>S+ 0 0 0 -4,-2.0 5,-2.1 2,-0.2 3,-0.8 0.872 109.3 51.7 -61.1 -41.2 -35.0 20.8 -9.0 126 153 A R H ><5S+ 0 0 106 -4,-1.8 3,-2.2 1,-0.3 -2,-0.2 0.896 102.5 59.9 -64.2 -38.6 -34.8 19.6 -12.6 127 154 A S H 3<5S+ 0 0 81 -4,-2.1 -1,-0.3 1,-0.3 -2,-0.2 0.764 102.2 54.4 -63.5 -18.0 -34.0 23.1 -13.7 128 155 A L T <<5S- 0 0 31 -3,-0.8 -1,-0.3 -4,-0.6 -2,-0.2 0.466 125.6-102.7 -93.4 0.1 -30.9 22.8 -11.4 129 156 A G T < 5S+ 0 0 60 -3,-2.2 2,-0.8 1,-0.3 -3,-0.2 0.562 79.4 137.5 89.2 8.1 -29.7 19.7 -13.1 130 157 A D < + 0 0 6 -5,-2.1 -1,-0.3 1,-0.1 -2,-0.2 -0.813 23.1 172.5 -89.5 108.4 -31.0 17.5 -10.3 131 158 A E + 0 0 159 -2,-0.8 -1,-0.1 -3,-0.1 -5,-0.1 0.404 69.5 57.0 -98.6 10.3 -32.6 14.5 -12.0 132 159 A T S S+ 0 0 25 -7,-0.1 21,-0.2 23,-0.1 -1,-0.1 0.845 76.7 95.5-108.1 -48.0 -33.2 12.5 -8.8 133 160 A F + 0 0 0 -8,-0.1 2,-0.3 19,-0.1 21,-0.2 -0.216 45.5 173.3 -49.6 135.9 -35.2 14.6 -6.5 134 161 A R - 0 0 98 19,-1.2 2,-0.5 16,-0.1 19,-0.2 -0.965 16.3-168.1-146.2 130.7 -39.0 14.1 -6.5 135 162 A L + 0 0 3 -2,-0.3 -13,-0.2 -17,-0.3 3,-0.1 -0.984 16.7 162.9-112.0 130.0 -41.6 15.6 -4.3 136 163 A D + 0 0 54 -2,-0.5 2,-0.2 1,-0.2 -17,-0.2 0.676 54.8 34.0-120.3 -28.4 -44.9 13.9 -4.6 137 164 A R - 0 0 29 -19,-0.1 -1,-0.2 -20,-0.1 2,-0.1 -0.773 67.2-121.5-130.9 172.0 -47.0 14.9 -1.5 138 165 A T > - 0 0 68 -2,-0.2 4,-1.9 1,-0.1 3,-0.2 -0.290 56.6 -32.9-101.1-179.7 -47.6 17.7 0.9 139 166 A E T 4 S+ 0 0 2 1,-0.3 -1,-0.1 -34,-0.2 -34,-0.0 -0.704 117.2 11.5 -76.9 142.2 -47.2 17.7 4.7 140 167 A P T >4 S+ 0 0 38 0, 0.0 3,-1.1 0, 0.0 -1,-0.3 -0.980 122.9 53.2 -99.7 1.6 -47.6 15.7 6.7 141 168 A T G >4 S+ 0 0 89 1,-0.2 3,-1.8 -3,-0.2 -2,-0.2 0.689 88.8 78.2 -69.1 -18.3 -47.9 12.5 4.4 142 169 A L G 3< S+ 0 0 0 -4,-1.9 -100,-0.5 1,-0.3 3,-0.3 0.643 88.7 65.9 -65.1 -7.8 -44.6 13.1 2.5 143 170 A N G < + 0 0 15 -3,-1.1 69,-2.2 -5,-0.2 -1,-0.3 0.234 61.8 103.5 -93.5 7.7 -43.1 11.7 5.7 144 171 A T < - 0 0 33 -3,-1.8 -1,-0.2 67,-0.2 -2,-0.1 0.878 57.3-169.6 -60.9 -35.5 -44.4 8.1 5.6 145 172 A A - 0 0 7 -3,-0.3 -105,-0.1 1,-0.2 -1,-0.1 0.804 9.1-174.6 55.3 38.3 -40.9 6.9 4.4 146 173 A I > - 0 0 79 1,-0.1 3,-2.6 2,-0.1 -1,-0.2 -0.458 34.7 -99.2 -68.5 130.4 -42.1 3.4 3.5 147 174 A P T 3 S+ 0 0 64 0, 0.0 -1,-0.1 0, 0.0 -108,-0.1 -0.247 107.2 9.1 -54.2 130.6 -39.2 1.1 2.5 148 175 A G T 3 S+ 0 0 80 1,-0.3 -2,-0.1 -110,-0.2 -109,-0.0 0.305 92.6 129.7 82.0 -8.1 -38.9 0.9 -1.3 149 176 A D < - 0 0 22 -3,-2.6 -1,-0.3 1,-0.1 -4,-0.0 -0.694 43.9-161.7 -81.1 122.2 -41.5 3.7 -1.8 150 177 A P > + 0 0 48 0, 0.0 3,-1.0 0, 0.0 -1,-0.1 0.635 51.8 114.7 -82.3 -10.1 -39.9 6.1 -4.3 151 178 A R T 3 S+ 0 0 106 1,-0.2 -6,-0.1 -111,-0.1 3,-0.1 -0.327 85.9 2.6 -65.0 137.7 -42.2 9.0 -3.5 152 179 A D T 3 S+ 0 0 0 1,-0.2 -111,-2.2 -112,-0.1 -110,-0.6 0.855 105.2 123.4 54.5 42.8 -40.6 12.1 -1.9 153 180 A T E < +E 40 0B 9 -3,-1.0 -19,-1.2 -113,-0.3 2,-0.3 -0.827 32.4 172.0-122.7 166.1 -37.1 10.6 -2.0 154 181 A T E -E 39 0B 0 -115,-1.8 -115,-3.0 -2,-0.3 -21,-0.1 -0.834 35.5-102.2-153.6-177.1 -33.7 11.5 -3.4 155 182 A T > - 0 0 16 -2,-0.3 4,-2.7 -117,-0.2 5,-0.2 -0.834 28.2-115.5-109.1 159.2 -30.2 10.0 -3.1 156 183 A P H > S+ 0 0 0 0, 0.0 4,-2.3 0, 0.0 5,-0.2 0.883 115.8 48.5 -62.4 -39.5 -27.4 11.4 -0.8 157 184 A L H > S+ 0 0 45 -122,-2.2 4,-2.5 2,-0.2 5,-0.2 0.937 112.2 48.0 -67.0 -46.3 -25.2 12.2 -3.7 158 185 A A H > S+ 0 0 5 -123,-0.5 4,-2.1 1,-0.2 5,-0.2 0.936 115.0 45.9 -58.0 -46.2 -27.9 14.0 -5.7 159 186 A M H X S+ 0 0 0 -4,-2.7 4,-2.3 2,-0.2 5,-0.2 0.856 111.3 52.4 -67.2 -33.6 -28.9 15.9 -2.6 160 187 A A H X S+ 0 0 0 -4,-2.3 4,-2.5 -5,-0.2 -2,-0.2 0.962 111.5 46.4 -64.6 -45.1 -25.2 16.7 -1.8 161 188 A Q H X S+ 0 0 87 -4,-2.5 4,-2.1 1,-0.2 -2,-0.2 0.875 115.2 46.9 -61.3 -44.0 -24.6 18.1 -5.3 162 189 A T H X S+ 0 0 2 -4,-2.1 4,-2.0 -5,-0.2 -1,-0.2 0.885 111.4 49.0 -68.8 -41.1 -27.8 20.1 -5.2 163 190 A L H X S+ 0 0 0 -4,-2.3 4,-2.0 2,-0.2 5,-0.4 0.916 110.7 52.6 -66.2 -38.6 -27.2 21.6 -1.8 164 191 A K H X>S+ 0 0 49 -4,-2.5 4,-2.7 -5,-0.2 5,-1.0 0.960 110.0 47.6 -57.2 -50.3 -23.7 22.5 -2.9 165 192 A N H <5S+ 0 0 37 -4,-2.1 6,-1.7 1,-0.2 4,-0.5 0.852 113.1 49.4 -60.1 -37.9 -25.0 24.3 -6.0 166 193 A L H <5S+ 0 0 0 -4,-2.0 -1,-0.2 5,-0.2 -2,-0.2 0.822 123.5 26.1 -69.7 -39.1 -27.7 26.2 -3.9 167 194 A T H <5S+ 0 0 0 -4,-2.0 -2,-0.2 -5,-0.2 -3,-0.2 0.782 140.2 14.0-102.8 -24.6 -25.4 27.5 -1.2 168 195 A L T <5S+ 0 0 62 -4,-2.7 -3,-0.2 -5,-0.4 -2,-0.1 0.499 118.3 49.8-127.8 -7.9 -21.9 27.7 -2.8 169 196 A G S - 0 0 44 -2,-0.3 4,-3.0 1,-0.1 3,-0.4 -0.303 49.7 -96.6 -59.4 159.6 -28.1 34.8 -7.7 174 201 A E H > S+ 0 0 112 1,-0.2 4,-2.8 2,-0.2 5,-0.2 0.868 120.5 50.2 -55.9 -48.5 -25.9 36.2 -5.0 175 202 A T H > S+ 0 0 120 1,-0.2 4,-1.5 2,-0.2 -1,-0.2 0.904 117.7 41.5 -57.7 -42.7 -28.5 38.0 -2.8 176 203 A Q H > S+ 0 0 28 -3,-0.4 4,-2.8 2,-0.2 5,-0.2 0.897 112.4 54.1 -72.7 -41.4 -30.8 34.9 -2.8 177 204 A R H X S+ 0 0 59 -4,-3.0 4,-2.5 1,-0.2 -2,-0.2 0.957 109.6 48.4 -55.2 -49.1 -27.9 32.5 -2.3 178 205 A A H X S+ 0 0 30 -4,-2.8 4,-2.3 -5,-0.2 -1,-0.2 0.861 110.2 52.3 -61.7 -37.9 -26.9 34.6 0.8 179 206 A Q H X S+ 0 0 64 -4,-1.5 4,-2.5 -5,-0.2 -1,-0.2 0.914 109.0 48.9 -64.1 -46.9 -30.5 34.5 2.1 180 207 A L H X S+ 0 0 0 -4,-2.8 4,-2.2 1,-0.2 5,-0.2 0.960 111.8 49.8 -57.2 -46.7 -30.7 30.8 1.8 181 208 A V H X S+ 0 0 13 -4,-2.5 4,-2.2 -5,-0.2 -2,-0.2 0.902 108.8 52.1 -61.1 -40.0 -27.4 30.5 3.6 182 209 A T H X S+ 0 0 94 -4,-2.3 4,-1.4 1,-0.2 -1,-0.2 0.956 110.0 50.0 -61.5 -45.5 -28.6 32.8 6.4 183 210 A W H < S+ 0 0 13 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.895 111.1 47.2 -56.9 -48.4 -31.7 30.7 6.9 184 211 A L H >< S+ 0 0 0 -4,-2.2 3,-1.6 1,-0.2 22,-1.4 0.888 109.8 52.8 -64.1 -40.6 -29.7 27.4 7.1 185 212 A K H 3< S+ 0 0 78 -4,-2.2 -1,-0.2 20,-0.3 -2,-0.2 0.780 106.2 54.2 -67.0 -24.7 -27.2 28.8 9.6 186 213 A G T 3< S+ 0 0 27 -4,-1.4 -1,-0.3 -3,-0.2 -2,-0.2 0.255 77.9 138.7 -90.4 10.4 -30.0 29.9 11.9 187 214 A N < - 0 0 10 -3,-1.6 -86,-0.2 1,-0.1 3,-0.2 -0.313 35.5-167.6 -55.4 137.0 -31.5 26.4 11.9 188 215 A T S S+ 0 0 81 -87,-2.1 3,-0.3 1,-0.1 -1,-0.1 0.548 72.2 62.4-101.7 -9.6 -32.7 25.7 15.5 189 216 A T S S+ 0 0 49 -88,-0.3 3,-0.3 1,-0.2 -1,-0.1 0.371 83.0 73.6 -99.2 1.9 -33.3 21.9 15.2 190 217 A G > > + 0 0 0 1,-0.2 3,-1.2 -3,-0.2 5,-0.7 0.270 53.0 110.0-108.5 17.0 -30.0 20.3 14.4 191 218 A S T 3 5S+ 0 0 91 -3,-0.3 -1,-0.2 1,-0.3 -2,-0.1 0.809 86.1 42.6 -61.0 -34.5 -27.9 20.5 17.6 192 219 A A T 3 5S+ 0 0 51 -3,-0.3 59,-0.3 3,-0.1 -1,-0.3 0.529 112.4 60.2 -92.3 0.2 -27.9 16.7 18.2 193 220 A S T X>5S- 0 0 0 -3,-1.2 3,-1.3 57,-0.1 4,-0.6 0.489 119.1 -22.0-100.3-127.9 -27.3 15.7 14.5 194 221 A I G >45S+ 0 0 0 1,-0.3 3,-1.9 2,-0.2 4,-0.3 0.911 131.3 61.7 -52.4 -45.2 -24.4 16.5 12.2 195 222 A R G >4 - 0 0 61 0, 0.0 3,-1.0 0, 0.0 -1,-0.1 -0.257 46.1-122.7 -52.1 141.4 -15.5 20.6 16.1 200 227 A K T 3 S+ 0 0 215 1,-0.2 -2,-0.0 -4,-0.1 -3,-0.0 0.779 105.8 57.4 -64.0 -24.0 -17.5 23.1 18.1 201 228 A S T 3 S+ 0 0 70 2,-0.1 -1,-0.2 0, 0.0 2,-0.1 0.663 80.7 103.7 -87.3 -13.8 -16.0 26.2 16.4 202 229 A W S < S- 0 0 24 -3,-1.0 2,-0.4 -7,-0.1 -4,-0.1 -0.373 72.0-126.7 -64.8 144.2 -17.0 25.2 12.8 203 230 A V E -C 223 0A 84 20,-1.4 20,-3.1 -2,-0.1 2,-0.4 -0.809 31.5-174.2 -95.9 134.0 -19.9 27.1 11.4 204 231 A V E -C 222 0A 4 -2,-0.4 2,-0.4 18,-0.2 18,-0.2 -0.968 22.2-167.7-131.7 138.3 -22.7 24.9 10.0 205 232 A G E +C 221 0A 0 16,-2.7 16,-3.4 -2,-0.4 2,-0.3 -0.996 32.4 158.0-119.0 130.7 -25.9 25.5 8.1 206 233 A D E -C 220 0A 0 -22,-1.4 2,-0.4 -2,-0.4 14,-0.2 -0.943 35.9-145.8-147.0 161.5 -28.1 22.4 8.1 207 234 A K E -C 219 0A 0 12,-2.2 12,-1.6 -2,-0.3 2,-0.1 -0.993 20.7-155.0-131.8 122.2 -31.7 21.2 7.7 208 235 A T E -C 218 0A 14 -2,-0.4 2,-0.3 -108,-0.2 10,-0.3 -0.437 9.4-171.5 -83.9 168.4 -32.9 18.1 9.7 209 236 A G E +C 217 0A 4 8,-2.0 8,-3.0 -166,-0.2 2,-0.3 -0.925 6.1 179.1-156.7 142.8 -35.7 15.8 8.8 210 237 A S E +C 216 0A 62 -2,-0.3 -167,-0.3 6,-0.2 2,-0.2 -0.996 12.6 147.2-140.6 151.4 -37.4 13.0 10.5 211 238 A G E > -C 215 0A 12 4,-1.6 4,-0.6 -2,-0.3 3,-0.3 -0.816 48.2 -40.8-157.0-164.7 -40.3 10.6 9.6 212 240 A D T >4 S+ 0 0 63 -69,-2.2 3,-1.4 -2,-0.2 -1,-0.2 -0.052 110.1 45.9 -66.2 173.7 -41.7 7.1 10.0 213 241 A Y T 34 S- 0 0 34 28,-2.2 25,-2.5 1,-0.3 -1,-0.2 0.787 130.8 -76.1 58.1 30.5 -39.5 4.0 9.9 214 242 A G T 34 S+ 0 0 1 27,-0.6 32,-0.4 29,-0.6 -1,-0.3 0.810 77.7 177.9 53.4 30.5 -37.2 5.9 12.3 215 243 A T E << -C 211 0A 0 -3,-1.4 -4,-1.6 -4,-0.6 2,-0.4 -0.485 4.4-178.2 -70.1 127.5 -36.0 7.9 9.3 216 244 A T E +CD 210 236A 1 20,-3.3 20,-0.7 -6,-0.2 2,-0.3 -0.917 5.9 168.6-141.0 114.3 -33.4 10.4 10.5 217 245 A N E +CD 209 235A 0 -8,-3.0 -8,-2.0 -2,-0.4 2,-0.3 -0.834 14.3 174.6-129.1 156.5 -31.8 12.8 8.1 218 246 A D E -CD 208 234A 0 16,-1.6 16,-2.8 -2,-0.3 2,-0.4 -0.938 8.8-166.2-157.0 140.0 -29.6 16.0 8.1 219 247 A I E +CD 207 233A 0 -12,-1.6 -12,-2.2 -2,-0.3 2,-0.4 -0.995 21.7 179.8-127.1 137.7 -28.0 17.9 5.2 220 248 A A E -CD 206 232A 0 12,-3.6 12,-3.1 -2,-0.4 2,-0.4 -0.990 32.1-149.0-144.1 144.5 -25.4 20.5 6.0 221 249 A V E -CD 205 231A 0 -16,-3.4 -16,-2.7 -2,-0.4 2,-0.4 -0.957 29.0-162.2-107.9 136.0 -23.0 23.0 4.6 222 250 A I E -CD 204 230A 0 8,-2.8 8,-2.4 -2,-0.4 -18,-0.2 -0.968 14.0-163.9-126.1 129.0 -19.9 23.3 6.8 223 251 A W E -C 203 0A 49 -20,-3.1 -20,-1.4 -2,-0.4 5,-0.1 -0.845 15.9-154.8-113.3 97.8 -17.3 26.1 6.9 224 252 A P > - 0 0 13 0, 0.0 3,-0.6 0, 0.0 -22,-0.0 -0.219 25.8-112.5 -69.8 167.6 -14.1 25.1 8.7 225 254 A E T 3 S+ 0 0 110 1,-0.2 3,-0.0 3,-0.0 -23,-0.0 0.806 109.4 12.7 -66.5 -35.7 -11.9 27.7 10.3 226 255 A N T 3 S+ 0 0 159 2,-0.1 2,-0.3 0, 0.0 -1,-0.2 -0.175 118.4 66.2-136.5 30.7 -9.0 27.3 7.9 227 256 A H S < S- 0 0 113 -3,-0.6 3,-0.1 34,-0.0 34,-0.0 -0.980 85.5 -85.3-149.4 161.1 -10.3 25.2 5.0 228 257 A A - 0 0 37 -2,-0.3 -202,-0.2 1,-0.1 -2,-0.1 -0.250 63.7 -82.3 -64.9 156.2 -12.8 25.4 2.1 229 258 A P - 0 0 22 0, 0.0 -204,-1.6 0, 0.0 2,-0.4 -0.135 38.3-145.7 -61.9 155.1 -16.4 24.4 2.9 230 259 A L E -AD 24 222A 0 -8,-2.4 -8,-2.8 -206,-0.2 2,-0.5 -0.937 3.6-146.7-116.7 148.9 -17.6 20.8 3.1 231 260 A V E -AD 23 221A 0 -208,-2.4 -208,-2.2 -2,-0.4 2,-0.4 -0.947 21.1-175.3-114.5 128.6 -21.1 19.7 2.0 232 261 A L E -AD 22 220A 0 -12,-3.1 -12,-3.6 -2,-0.5 2,-0.4 -0.979 13.7-179.6-134.7 125.3 -22.4 16.8 4.0 233 262 A V E -AD 21 219A 0 -212,-2.5 -212,-2.1 -2,-0.4 2,-0.5 -0.990 5.1-177.3-116.6 127.6 -25.7 14.8 3.7 234 263 A T E +AD 20 218A 0 -16,-2.8 -16,-1.6 -2,-0.4 2,-0.4 -0.957 2.8 179.9-127.4 116.1 -26.5 11.9 6.1 235 264 A Y E +AD 19 217A 0 -216,-4.3 -216,-4.3 -2,-0.5 2,-0.3 -0.935 3.3 174.6-115.1 142.4 -29.6 9.8 5.6 236 265 A F E +AD 18 216A 0 -20,-0.7 -20,-3.3 -2,-0.4 2,-0.3 -0.988 2.1 168.3-147.6 134.2 -30.6 6.9 7.8 237 266 A T E -A 17 0A 11 -220,-2.3 -220,-3.1 -2,-0.3 -23,-0.2 -0.959 17.4-142.6-146.5 162.8 -33.8 4.8 7.9 238 267 A Q - 0 0 13 -25,-2.5 -222,-0.2 -2,-0.3 -23,-0.1 -0.777 22.8-117.3-129.7 167.6 -34.9 1.5 9.7 239 268 A P S S+ 0 0 91 0, 0.0 2,-0.5 0, 0.0 -25,-0.1 0.705 90.3 72.3 -85.4 -15.2 -37.0 -1.6 8.8 240 269 A E S > S- 0 0 100 -27,-0.1 3,-2.0 1,-0.1 -2,-0.1 -0.858 75.8-135.8-103.6 135.4 -39.8 -1.2 11.4 241 270 A Q T 3 S+ 0 0 93 -2,-0.5 -28,-2.2 1,-0.3 -27,-0.6 0.809 103.8 43.7 -52.9 -34.9 -42.4 1.6 11.1 242 271 A K T 3 S+ 0 0 172 -29,-0.2 -1,-0.3 -30,-0.2 3,-0.1 0.266 80.7 140.6-103.4 15.6 -42.3 2.6 14.7 243 272 A A < - 0 0 14 -3,-2.0 -29,-0.6 1,-0.1 2,-0.2 -0.095 59.2-103.7 -50.1 149.5 -38.5 2.6 15.1 244 273 A E - 0 0 135 -31,-0.1 -1,-0.1 -30,-0.1 2,-0.1 -0.561 35.6-107.9 -75.1 144.8 -37.1 5.5 17.2 245 274 A N - 0 0 67 -2,-0.2 2,-0.3 -3,-0.1 3,-0.1 -0.469 30.1-152.1 -69.1 148.2 -35.4 8.3 15.4 246 275 A R >> + 0 0 61 -32,-0.4 3,-1.2 1,-0.1 4,-0.8 -0.645 29.2 162.9-129.4 73.1 -31.6 8.2 15.9 247 276 A N H 3> S+ 0 0 74 -2,-0.3 4,-1.7 1,-0.2 3,-0.4 0.846 76.6 66.5 -59.5 -30.2 -29.9 11.6 15.6 248 277 A D H 3> S+ 0 0 81 1,-0.2 4,-2.2 2,-0.2 -1,-0.2 0.720 93.1 58.5 -63.8 -28.2 -26.9 10.2 17.4 249 278 A I H <> S+ 0 0 7 -3,-1.2 4,-2.8 2,-0.2 -1,-0.2 0.918 106.0 47.9 -66.8 -39.7 -26.1 7.9 14.4 250 279 A L H X S+ 0 0 0 -4,-0.8 4,-2.5 -3,-0.4 -2,-0.2 0.855 112.8 49.2 -64.9 -43.5 -25.9 11.0 12.0 251 280 A A H X S+ 0 0 13 -4,-1.7 4,-2.6 -59,-0.3 -1,-0.2 0.914 111.8 48.8 -60.3 -46.3 -23.6 12.7 14.6 252 281 A A H X S+ 0 0 26 -4,-2.2 4,-2.0 1,-0.2 -2,-0.2 0.902 112.7 48.8 -61.0 -42.6 -21.6 9.4 14.7 253 282 A A H X S+ 0 0 0 -4,-2.8 4,-2.1 2,-0.2 -2,-0.2 0.895 109.3 51.2 -66.3 -39.5 -21.5 9.4 10.9 254 283 A A H X S+ 0 0 0 -4,-2.5 4,-1.7 1,-0.2 -2,-0.2 0.953 109.3 51.2 -64.8 -39.5 -20.3 13.1 10.8 255 284 A K H X S+ 0 0 138 -4,-2.6 4,-0.5 1,-0.2 -1,-0.2 0.915 110.3 50.2 -61.7 -43.2 -17.5 12.3 13.2 256 285 A I H >< S+ 0 0 31 -4,-2.0 3,-1.1 1,-0.2 -2,-0.2 0.972 113.6 42.0 -59.8 -52.9 -16.3 9.4 11.1 257 286 A V H 3< S+ 0 0 1 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.693 113.8 50.3 -76.8 -17.8 -16.2 11.2 7.7 258 287 A T H >< S+ 0 0 10 -4,-1.7 3,-2.0 -5,-0.2 2,-1.2 0.461 73.9 117.7 -99.2 3.5 -14.6 14.4 8.9 259 288 A H T << S+ 0 0 152 -3,-1.1 -256,-0.0 -4,-0.5 -4,-0.0 -0.558 74.7 44.6 -69.2 101.5 -11.8 12.8 10.8 260 289 A G T 3 0 0 75 -2,-1.2 -1,-0.3 1,-0.5 -2,-0.1 0.255 360.0 360.0 139.7 -5.3 -9.0 14.3 8.8 261 290 A F < 0 0 68 -3,-2.0 -1,-0.5 -34,-0.0 -3,-0.0 -0.607 360.0 360.0-120.7 360.0 -10.0 17.9 8.5