==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=25-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 22-SEP-98 1BV3 . COMPND 2 MOLECULE: PROTEIN (CARBONIC ANHYDRASE II); . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR F.BRIGANTI,S.MANGANI,A.SCOZZAFAVA,G.VERNAGLIONE,C.T.SUPURAN . 256 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11909.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 159 62.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 55 21.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 20 7.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 36 14.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 2 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A H 0 0 174 0, 0.0 2,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 175.5 9.8 0.2 8.7 2 5 A W + 0 0 58 1,-0.1 2,-0.2 2,-0.1 7,-0.2 -0.339 360.0 130.8 -70.0 160.0 7.6 -1.5 11.3 3 6 A G - 0 0 11 5,-2.8 10,-0.1 2,-0.2 -1,-0.1 -0.753 65.1 -74.7-171.5-150.4 5.4 -4.3 10.5 4 7 A Y S S+ 0 0 37 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.171 82.7 111.3-119.9 22.4 4.4 -7.8 11.6 5 8 A G S > S- 0 0 38 1,-0.1 4,-1.6 4,-0.1 -2,-0.2 -0.282 82.5 -98.8 -86.4-179.4 7.4 -9.8 10.4 6 9 A K T 4 S+ 0 0 155 1,-0.2 3,-0.1 2,-0.2 5,-0.1 0.912 123.6 39.3 -65.3 -38.0 10.1 -11.7 12.3 7 10 A H T 4 S+ 0 0 159 1,-0.2 -1,-0.2 4,-0.0 -5,-0.0 0.655 131.5 21.4 -92.0 -16.9 12.5 -8.8 11.7 8 11 A N T 4 S+ 0 0 61 -3,-0.1 -5,-2.8 -6,-0.1 -2,-0.2 0.177 94.0 120.2-134.6 28.4 10.2 -5.8 12.2 9 12 A G S >X S- 0 0 4 -4,-1.6 3,-3.2 -5,-0.2 4,-0.7 -0.042 81.6 -66.5 -89.1-174.1 7.3 -7.1 14.2 10 13 A P T 34 S+ 0 0 32 0, 0.0 3,-0.5 0, 0.0 4,-0.4 0.701 126.1 60.3 -44.5 -37.3 6.0 -6.1 17.7 11 14 A E T 34 S+ 0 0 66 1,-0.2 3,-0.1 2,-0.1 4,-0.1 0.640 109.2 45.9 -75.4 -0.6 9.0 -7.2 19.7 12 15 A H T X> S+ 0 0 50 -3,-3.2 3,-1.8 1,-0.1 4,-0.5 0.536 87.0 89.8-102.0 -20.1 11.1 -4.7 17.7 13 16 A W H >X S+ 0 0 4 -4,-0.7 4,-2.4 -3,-0.5 3,-1.0 0.801 73.9 68.0 -54.4 -31.6 8.8 -1.8 17.9 14 17 A H H 34 S+ 0 0 67 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.764 87.7 67.4 -60.7 -27.8 10.2 -0.4 21.1 15 18 A K H <4 S+ 0 0 136 -3,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.893 116.4 25.2 -62.8 -36.5 13.5 0.5 19.4 16 19 A D H << S+ 0 0 105 -3,-1.0 -2,-0.2 -4,-0.5 -1,-0.2 0.695 135.7 33.8 -96.3 -22.9 11.7 3.2 17.3 17 20 A F >< - 0 0 47 -4,-2.4 3,-2.7 1,-0.1 -1,-0.2 -0.812 64.3-175.4-135.9 84.5 8.8 3.9 19.7 18 21 A P G > S+ 0 0 101 0, 0.0 3,-1.9 0, 0.0 -4,-0.1 0.680 77.5 77.2 -58.2 -20.9 9.9 3.5 23.3 19 22 A I G > S+ 0 0 58 1,-0.3 3,-3.0 2,-0.2 -5,-0.1 0.621 70.9 87.9 -63.4 -15.8 6.3 4.1 24.6 20 23 A A G < S+ 0 0 7 -3,-2.7 -1,-0.3 1,-0.3 -6,-0.1 0.735 91.3 45.6 -51.9 -25.0 5.9 0.4 23.4 21 24 A K G < S+ 0 0 139 -3,-1.9 -1,-0.3 -4,-0.1 -2,-0.2 0.122 94.9 128.1-107.7 25.0 7.0 -0.4 27.0 22 25 A G S < S- 0 0 18 -3,-3.0 3,-0.5 1,-0.1 -3,-0.0 0.060 71.2-104.6 -73.0-173.9 4.8 2.2 28.6 23 26 A E S S+ 0 0 125 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.565 111.4 42.0 -89.1 -16.8 2.3 2.0 31.5 24 27 A R S S+ 0 0 47 224,-0.1 -1,-0.2 168,-0.1 2,-0.1 -0.156 80.0 148.9-131.0 51.0 -0.9 2.1 29.5 25 28 A Q - 0 0 4 -3,-0.5 220,-0.1 221,-0.2 170,-0.1 -0.414 34.3-101.1 -89.7 153.9 -0.3 -0.1 26.5 26 29 A S S S+ 0 0 0 168,-0.4 2,-0.1 -2,-0.1 -2,-0.0 -0.834 75.1 38.9-121.6 158.5 -2.9 -2.2 24.5 27 30 A P + 0 0 0 0, 0.0 218,-2.5 0, 0.0 2,-0.3 0.650 64.2 173.2 -78.7 174.1 -4.2 -4.8 23.8 28 31 A V - 0 0 1 216,-0.2 77,-1.1 -2,-0.1 2,-0.5 -0.913 37.3 -98.1-134.9 174.2 -4.6 -6.8 27.1 29 32 A D E -a 105 0A 37 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.810 31.9-134.6 -89.4 144.7 -6.2 -9.9 28.2 30 33 A I E -a 106 0A 0 75,-3.4 77,-2.5 -2,-0.5 2,-0.8 -0.832 15.9-161.6 -96.6 108.0 -9.6 -9.4 29.8 31 34 A D >> - 0 0 66 -2,-0.8 3,-1.9 75,-0.2 4,-1.7 -0.786 3.1-160.9 -87.8 107.5 -9.6 -11.6 33.0 32 35 A T T 34 S+ 0 0 48 -2,-0.8 -1,-0.1 1,-0.3 222,-0.0 0.720 86.5 56.2 -72.0 -17.0 -13.3 -11.9 33.6 33 36 A H T 34 S+ 0 0 158 1,-0.1 -1,-0.3 3,-0.0 -2,-0.0 0.200 112.3 41.8 -89.0 -4.3 -12.8 -12.9 37.3 34 37 A T T <4 S+ 0 0 94 -3,-1.9 -2,-0.2 2,-0.0 218,-0.2 0.536 92.6 96.2-116.6 -12.6 -10.7 -9.8 38.0 35 38 A A < - 0 0 21 -4,-1.7 2,-0.4 216,-0.1 218,-0.2 -0.327 67.4-145.3 -68.4 154.9 -12.9 -7.3 36.1 36 39 A K E -c 253 0B 127 216,-1.7 218,-2.2 -2,-0.0 2,-0.1 -0.991 12.3-117.9-129.8 138.6 -15.4 -5.5 38.4 37 40 A Y E -c 254 0B 100 -2,-0.4 218,-0.2 216,-0.2 220,-0.1 -0.450 25.9-157.2 -70.2 141.9 -19.0 -4.4 37.6 38 41 A D > - 0 0 26 216,-2.1 3,-1.4 -2,-0.1 -1,-0.0 -0.968 11.4-168.0-128.0 108.2 -19.3 -0.6 37.9 39 42 A P T 3 S+ 0 0 99 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.593 85.5 69.6 -71.4 -8.8 -22.9 0.6 38.5 40 43 A S T 3 S+ 0 0 83 2,-0.1 2,-0.3 -3,-0.0 215,-0.1 0.515 77.3 102.1 -89.6 -8.4 -21.7 4.1 37.7 41 44 A L < - 0 0 28 -3,-1.4 3,-0.1 213,-0.2 38,-0.0 -0.596 64.6-143.7 -75.7 136.9 -21.2 3.2 34.1 42 45 A K - 0 0 123 37,-1.0 39,-0.1 -2,-0.3 -2,-0.1 -0.567 28.0 -89.2 -97.4 161.9 -23.9 4.4 31.6 43 46 A P - 0 0 111 0, 0.0 36,-1.7 0, 0.0 2,-0.3 -0.362 49.6-105.5 -61.8 146.6 -25.2 2.6 28.6 44 47 A L E -D 78 0B 17 34,-0.3 2,-0.5 141,-0.2 34,-0.2 -0.580 25.6-149.5 -69.8 146.7 -23.3 3.3 25.4 45 48 A S E -D 77 0B 45 32,-2.9 32,-2.2 -2,-0.3 2,-0.6 -0.973 13.6-174.3-118.6 111.2 -25.0 5.6 22.9 46 49 A V E -D 76 0B 34 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.966 2.0-177.7-104.4 112.9 -24.0 4.8 19.3 47 50 A S E +D 75 0B 33 28,-3.4 28,-2.2 -2,-0.6 3,-0.2 -0.792 25.1 141.6-115.6 90.4 -25.5 7.3 16.9 48 51 A Y > + 0 0 2 -2,-0.6 3,-1.9 26,-0.2 130,-0.2 0.150 31.9 108.9-110.4 8.7 -24.5 6.2 13.4 49 52 A D T 3 S+ 0 0 97 1,-0.3 -1,-0.1 -3,-0.1 25,-0.1 0.846 85.0 42.0 -61.9 -32.9 -27.6 6.9 11.4 50 53 A Q T 3 S+ 0 0 132 23,-0.9 -1,-0.3 -3,-0.2 24,-0.1 0.130 82.5 146.9-100.9 29.3 -26.0 9.9 9.5 51 54 A A < - 0 0 21 -3,-1.9 2,-0.6 1,-0.1 23,-0.1 -0.297 32.7-160.1 -60.4 135.9 -22.6 8.2 8.9 52 55 A T - 0 0 49 16,-0.3 16,-2.5 122,-0.1 2,-0.2 -0.909 4.9-163.9-118.7 95.1 -21.0 9.2 5.6 53 56 A S E +E 67 0B 0 -2,-0.6 121,-0.6 122,-0.3 14,-0.2 -0.591 11.2 175.6 -77.3 150.3 -18.3 6.7 4.5 54 57 A L E - 0 0 82 12,-3.2 118,-2.5 1,-0.4 2,-0.3 0.711 49.6 -7.2-120.5 -49.4 -15.9 7.9 1.8 55 58 A R E -EF 66 171B 88 11,-1.0 11,-3.1 116,-0.3 2,-0.4 -0.985 45.0-138.7-153.6 160.0 -13.1 5.5 0.9 56 59 A I E -EF 65 170B 0 114,-2.5 114,-2.5 -2,-0.3 2,-0.4 -0.976 27.3-175.4-125.0 143.0 -11.4 2.3 1.7 57 60 A L E -EF 64 169B 29 7,-2.0 7,-2.8 -2,-0.4 2,-0.6 -0.997 29.1-138.6-142.6 137.6 -7.7 2.0 1.6 58 61 A N - 0 0 0 110,-2.6 109,-2.6 -2,-0.4 110,-0.2 -0.814 21.7-175.6 -89.8 118.2 -4.9 -0.7 2.0 59 62 A N - 0 0 47 -2,-0.6 -1,-0.1 107,-0.2 107,-0.1 0.328 52.8 -99.2-103.3 11.8 -2.2 1.1 4.1 60 63 A G 0 0 16 166,-0.2 106,-0.1 168,-0.1 -2,-0.1 0.429 360.0 360.0 96.2 0.9 0.2 -1.7 3.9 61 64 A H 0 0 52 165,-0.1 166,-0.1 -58,-0.1 -3,-0.1 0.585 360.0 360.0-140.4 360.0 -0.8 -2.9 7.3 62 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 63 66 A F 0 0 4 0, 0.0 29,-0.5 0, 0.0 2,-0.5 0.000 360.0 360.0 360.0 134.3 -7.5 -1.8 5.3 64 67 A N E -E 57 0B 22 -7,-2.8 -7,-2.0 27,-0.1 2,-0.6 -0.924 360.0-152.6-106.8 140.1 -9.2 1.3 6.6 65 68 A V E -EG 56 90B 0 25,-3.2 25,-1.9 -2,-0.5 2,-0.3 -0.957 26.3-152.0-100.8 122.2 -12.8 2.5 5.8 66 69 A E E -EG 55 89B 49 -11,-3.1 -12,-3.2 -2,-0.6 -11,-1.0 -0.750 9.9-162.0-104.2 149.5 -12.7 6.3 6.2 67 70 A F E -E 53 0B 8 21,-2.8 2,-0.5 -2,-0.3 -14,-0.2 -0.808 31.0-102.1-122.9 153.1 -15.6 8.5 7.2 68 71 A D + 0 0 39 -16,-2.5 -16,-0.3 -2,-0.3 5,-0.3 -0.677 39.8 172.8 -71.7 119.7 -16.3 12.3 6.9 69 72 A D + 0 0 43 -2,-0.5 -1,-0.1 1,-0.1 17,-0.1 -0.102 46.1 108.1-114.5 21.5 -15.6 13.7 10.4 70 73 A S S S+ 0 0 80 56,-0.0 2,-0.3 2,-0.0 -1,-0.1 0.431 90.8 21.1 -79.4 0.1 -15.9 17.4 9.5 71 74 A Q S S- 0 0 116 -3,-0.2 2,-1.8 3,-0.1 3,-0.3 -0.943 98.4 -86.1-154.7 165.1 -19.2 17.3 11.4 72 75 A D S S+ 0 0 91 -2,-0.3 3,-0.2 1,-0.2 -22,-0.1 -0.399 74.3 128.8 -78.6 69.4 -21.1 15.3 14.1 73 76 A K S S+ 0 0 56 -2,-1.8 -23,-0.9 1,-0.3 2,-0.4 0.697 75.1 22.3 -93.9 -26.4 -22.6 12.7 11.7 74 77 A A S S+ 0 0 5 -3,-0.3 13,-2.6 -24,-0.1 2,-0.3 -0.915 84.5 164.1-149.5 102.9 -21.6 9.4 13.4 75 78 A V E -DH 47 86B 12 -28,-2.2 -28,-3.4 -2,-0.4 2,-0.4 -0.946 30.0-149.4-131.3 159.2 -20.8 9.7 17.1 76 79 A L E +DH 46 85B 0 9,-2.2 9,-2.3 -2,-0.3 2,-0.3 -0.992 28.6 151.9-122.0 133.9 -20.3 7.8 20.3 77 80 A K E +D 45 0B 81 -32,-2.2 -32,-2.9 -2,-0.4 7,-0.1 -0.836 38.6 42.8-148.4 174.8 -21.2 9.1 23.7 78 81 A G E > S+D 44 0B 23 3,-0.4 3,-2.1 5,-0.3 -34,-0.3 -0.336 72.6 87.6 83.0-159.3 -22.2 7.7 27.1 79 82 A G T 3 S- 0 0 2 -36,-1.7 -37,-1.0 1,-0.3 -1,-0.2 -0.398 120.6 -28.5 64.8-142.2 -20.6 4.6 28.5 80 83 A P T 3 S+ 0 0 39 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.403 115.6 112.2 -89.8 8.3 -17.4 5.7 30.3 81 84 A L < - 0 0 11 -3,-2.1 2,-0.5 -39,-0.1 -3,-0.4 -0.535 55.0-153.4 -93.0 145.8 -17.0 8.8 28.1 82 85 A D S S- 0 0 130 -2,-0.2 2,-0.1 53,-0.1 -1,-0.0 -0.932 70.4 -2.4-106.5 124.8 -17.4 12.5 28.8 83 86 A G S S- 0 0 45 -2,-0.5 2,-0.4 38,-0.1 -5,-0.3 -0.275 96.8 -50.9 91.7-178.5 -18.4 14.3 25.7 84 87 A T - 0 0 39 -7,-0.1 38,-2.0 -2,-0.1 2,-0.4 -0.881 41.9-161.2-103.2 138.4 -18.9 13.4 22.1 85 88 A Y E -HI 76 121B 4 -9,-2.3 -9,-2.2 -2,-0.4 2,-0.4 -0.966 13.3-140.4-120.0 137.1 -16.5 11.4 20.0 86 89 A R E -HI 75 120B 44 34,-3.1 34,-1.9 -2,-0.4 2,-0.3 -0.744 17.8-117.0 -99.3 143.1 -16.6 11.4 16.3 87 90 A L E + I 0 119B 2 -13,-2.6 32,-0.2 -2,-0.4 -14,-0.1 -0.486 37.4 165.5 -73.4 128.8 -16.1 8.3 14.0 88 91 A I E - 0 0 37 30,-2.5 -21,-2.8 1,-0.4 2,-0.3 0.772 59.6 -24.5-112.7 -37.4 -13.1 8.7 11.8 89 92 A Q E -GI 66 118B 36 29,-1.1 29,-2.9 -23,-0.2 -1,-0.4 -0.973 47.1-145.8-165.4 161.5 -12.3 5.2 10.4 90 93 A F E +GI 65 117B 0 -25,-1.9 -25,-3.2 -2,-0.3 2,-0.3 -0.945 22.4 165.1-130.4 160.3 -12.7 1.5 11.2 91 94 A H E - I 0 116B 31 25,-1.6 25,-2.7 -2,-0.3 2,-0.3 -0.917 24.0-125.1-158.5 168.2 -10.3 -1.4 10.3 92 95 A F E - I 0 115B 3 -29,-0.5 2,-0.3 -2,-0.3 23,-0.2 -0.788 2.5-152.5-118.3 167.7 -9.8 -5.1 11.3 93 96 A H E + I 0 114B 5 21,-1.4 21,-2.1 -2,-0.3 2,-0.3 -0.971 31.1 166.2-132.0 132.4 -6.9 -7.2 12.7 94 97 A W E - I 0 113B 0 -2,-0.3 146,-1.3 19,-0.2 145,-0.7 -0.957 24.6-119.9-149.0 174.5 -7.1 -10.9 11.7 95 98 A G - 0 0 0 17,-1.4 6,-0.1 5,-0.5 3,-0.1 -0.519 24.6-115.0-117.1-180.0 -5.0 -14.1 11.7 96 99 A S S S+ 0 0 44 -2,-0.2 2,-0.3 142,-0.2 5,-0.1 0.589 105.4 29.8 -80.6 -17.7 -3.7 -16.7 9.3 97 100 A L S > S- 0 0 112 3,-0.3 3,-1.5 15,-0.1 -2,-0.1 -0.953 90.7-107.9-133.4 160.5 -5.9 -19.4 10.9 98 101 A D T 3 S+ 0 0 70 -2,-0.3 48,-0.2 1,-0.3 -3,-0.1 0.702 109.7 67.1 -69.2 -13.3 -9.3 -19.2 12.7 99 102 A G T 3 S+ 0 0 59 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.370 107.3 34.1 -87.0 6.1 -7.8 -19.8 16.2 100 103 A Q < + 0 0 55 -3,-1.5 -5,-0.5 12,-0.1 -3,-0.3 -0.991 65.0 96.0-149.1 162.2 -6.0 -16.5 16.2 101 104 A G + 0 0 0 1,-0.4 13,-0.3 -2,-0.3 11,-0.2 0.067 56.2 105.6 146.7 -33.0 -6.4 -12.9 14.9 102 105 A S - 0 0 2 9,-2.1 -1,-0.4 11,-0.3 12,-0.1 -0.277 53.1-152.4 -70.2 158.3 -7.9 -10.8 17.8 103 106 A E S S+ 0 0 3 -10,-0.1 2,-0.1 138,-0.1 -1,-0.1 0.895 83.1 50.8 -95.5 -50.4 -5.7 -8.3 19.7 104 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.547 75.5-160.1 -74.8 158.0 -7.7 -8.5 23.0 105 108 A T E -a 29 0A 11 -77,-1.1 -75,-3.4 -2,-0.1 2,-0.5 -0.845 13.0-137.5-129.7 165.8 -8.4 -11.8 24.5 106 109 A V E > S-aB 30 109A 17 3,-1.8 3,-1.7 -2,-0.3 -75,-0.2 -0.971 89.0 -18.6-122.5 115.0 -11.0 -12.9 27.1 107 110 A D T 3 S- 0 0 73 -77,-2.5 -1,-0.2 -2,-0.5 -76,-0.1 0.842 129.1 -56.0 55.6 41.3 -9.8 -15.4 29.8 108 111 A K T 3 S+ 0 0 170 1,-0.2 2,-0.4 -78,-0.1 -1,-0.3 0.373 106.1 139.4 67.4 3.5 -6.9 -16.0 27.3 109 112 A K B < -B 106 0A 111 -3,-1.7 -3,-1.8 1,-0.0 2,-0.3 -0.613 40.1-152.0 -76.3 128.1 -9.4 -17.0 24.5 110 113 A K - 0 0 90 -2,-0.4 2,-0.2 -11,-0.2 -5,-0.1 -0.744 3.9-150.4 -99.7 138.8 -8.5 -15.6 21.0 111 114 A Y - 0 0 32 -7,-0.4 -9,-2.1 -2,-0.3 34,-0.2 -0.619 29.9-105.1 -99.2 172.2 -11.0 -14.8 18.3 112 115 A A S S- 0 0 4 32,-1.3 -17,-1.4 -11,-0.2 2,-0.3 0.698 92.9 -18.6 -73.5 -22.8 -10.6 -15.0 14.5 113 116 A A E -IJ 94 144B 0 31,-1.1 31,-2.0 -19,-0.2 2,-0.3 -0.967 57.9-135.6-168.5 174.4 -10.4 -11.2 14.1 114 117 A E E -IJ 93 143B 0 -21,-2.1 -21,-1.4 -13,-0.3 2,-0.4 -0.963 10.6-145.8-152.2 128.4 -11.3 -7.9 15.8 115 118 A L E -IJ 92 142B 0 27,-2.6 27,-2.2 -2,-0.3 2,-0.5 -0.817 11.5-161.4 -92.5 136.9 -12.9 -4.7 14.4 116 119 A H E -IJ 91 141B 4 -25,-2.7 -25,-1.6 -2,-0.4 2,-0.6 -0.984 4.5-165.2-123.8 118.4 -11.8 -1.3 15.8 117 120 A L E -IJ 90 140B 1 23,-2.1 23,-2.4 -2,-0.5 2,-0.4 -0.969 20.8-151.0-102.0 117.7 -14.1 1.8 15.2 118 121 A V E +IJ 89 139B 7 -29,-2.9 -30,-2.5 -2,-0.6 -29,-1.1 -0.847 18.8 176.6-102.7 133.2 -11.9 4.7 16.0 119 122 A H E -IJ 87 138B 0 19,-2.1 19,-2.0 -2,-0.4 2,-0.3 -0.939 15.3-148.1-133.4 150.6 -13.3 8.0 17.4 120 123 A W E -IJ 86 137B 5 -34,-1.9 -34,-3.1 -2,-0.3 2,-0.4 -0.951 28.4-106.2-125.8 145.9 -11.8 11.3 18.5 121 124 A N E > -I 85 0B 2 15,-2.2 3,-1.6 -2,-0.3 -36,-0.2 -0.548 22.0-150.5 -65.3 106.9 -13.0 13.8 21.2 122 125 A T G > S+ 0 0 38 -38,-2.0 3,-1.8 -2,-0.4 -1,-0.1 0.603 87.1 80.3 -66.5 -6.1 -14.5 16.8 19.4 123 127 A K G 3 S+ 0 0 139 1,-0.3 -1,-0.3 -39,-0.3 -38,-0.1 0.752 93.4 52.7 -65.8 -22.0 -13.4 19.1 22.4 124 128 A Y G < S- 0 0 46 -3,-1.6 2,-1.2 12,-0.1 -1,-0.3 0.361 103.4-134.9 -92.2 -0.7 -10.0 19.0 20.8 125 129 A G S < S+ 0 0 54 -3,-1.8 2,-0.3 4,-0.1 -3,-0.1 -0.132 72.0 25.3 80.8 -45.6 -11.0 20.1 17.3 126 130 A D S >> S- 0 0 68 -2,-1.2 4,-1.7 -5,-0.2 3,-0.6 -0.971 81.4-106.3-148.9 164.8 -9.1 17.7 15.1 127 131 A F H 3> S+ 0 0 69 -2,-0.3 4,-1.8 1,-0.2 -6,-0.1 0.881 114.3 61.1 -57.4 -38.1 -7.7 14.2 15.3 128 132 A G H 34 S+ 0 0 40 1,-0.2 -1,-0.2 2,-0.2 -3,-0.1 0.839 108.3 41.5 -61.6 -40.5 -4.1 15.5 15.5 129 133 A K H X4 S+ 0 0 113 -3,-0.6 3,-1.3 -5,-0.2 -1,-0.2 0.744 107.4 63.5 -77.4 -28.2 -4.7 17.4 18.7 130 134 A A H >< S+ 0 0 0 -4,-1.7 3,-1.8 1,-0.3 6,-0.3 0.837 94.6 61.3 -57.9 -36.0 -6.8 14.6 20.1 131 135 A V T 3< S+ 0 0 19 -4,-1.8 -1,-0.3 1,-0.3 -2,-0.1 0.309 95.5 60.9 -81.2 18.3 -3.7 12.3 20.1 132 136 A Q T < S+ 0 0 144 -3,-1.3 -1,-0.3 70,-0.1 -2,-0.2 0.365 95.6 79.1-115.5 12.9 -1.9 14.7 22.5 133 137 A Q S X S- 0 0 67 -3,-1.8 3,-1.6 1,-0.1 4,-0.3 -0.881 77.8-131.6-124.4 150.4 -4.5 14.2 25.3 134 138 A P T 3 S+ 0 0 85 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.798 113.2 36.9 -67.8 -21.1 -5.1 11.4 27.8 135 139 A D T 3 S+ 0 0 50 1,-0.1 -14,-0.1 56,-0.0 -53,-0.1 0.043 85.5 114.8-120.1 34.4 -8.8 11.3 26.8 136 140 A G S < S+ 0 0 0 -3,-1.6 -15,-2.2 -6,-0.3 2,-0.3 0.801 70.0 34.1 -76.5 -27.6 -8.5 12.0 23.1 137 141 A L E -Jk 120 203B 0 65,-2.8 67,-2.3 -4,-0.3 2,-0.4 -0.951 51.7-164.2-133.0 157.5 -9.7 8.9 21.6 138 142 A A E -Jk 119 204B 0 -19,-2.0 -19,-2.1 -2,-0.3 2,-0.5 -0.999 12.2-166.1-133.9 130.6 -12.3 6.1 22.1 139 143 A V E -Jk 118 205B 2 65,-1.8 67,-2.3 -2,-0.4 2,-0.6 -0.979 10.3-150.2-123.2 133.0 -12.1 2.8 20.2 140 144 A L E -Jk 117 206B 0 -23,-2.4 -23,-2.1 -2,-0.5 2,-0.4 -0.909 17.6-160.9 -97.5 115.6 -15.0 0.4 20.1 141 145 A G E -Jk 116 207B 0 65,-2.9 67,-2.7 -2,-0.6 2,-0.4 -0.866 9.7-176.4-106.5 132.9 -13.6 -3.1 19.7 142 146 A I E -J 115 0B 0 -27,-2.2 -27,-2.6 -2,-0.4 2,-0.2 -0.993 18.4-135.6-128.7 128.9 -15.8 -6.0 18.5 143 147 A F E -J 114 0B 0 65,-0.4 69,-2.5 -2,-0.4 2,-0.4 -0.539 11.9-148.9 -82.5 158.3 -14.7 -9.6 18.3 144 148 A L E -Jl 113 212B 0 -31,-2.0 -32,-1.3 67,-0.2 -31,-1.1 -0.987 12.2-174.7-128.4 122.0 -15.4 -11.8 15.2 145 149 A K E - l 0 213B 83 67,-2.4 69,-2.2 -2,-0.4 2,-0.4 -0.865 31.7-109.8-106.5 157.7 -15.9 -15.6 15.5 146 150 A V E S+ l 0 214B 43 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.739 74.0 90.8 -90.4 130.8 -16.3 -17.8 12.4 147 151 A G E S+ l 0 215B 39 67,-2.5 69,-0.6 -2,-0.4 2,-0.1 -0.617 77.2 16.9-168.9-116.2 -19.8 -19.3 11.9 148 152 A S S S- 0 0 91 -2,-0.2 -1,-0.2 67,-0.2 2,-0.0 -0.475 85.1 -96.8 -73.0 150.4 -22.7 -17.8 10.0 149 153 A A - 0 0 61 65,-0.3 65,-0.2 -2,-0.1 -1,-0.1 -0.248 27.6-132.7 -67.0 145.8 -22.1 -15.0 7.4 150 154 A K >> - 0 0 42 1,-0.2 3,-2.3 62,-0.1 4,-0.9 -0.867 11.3-157.7-102.0 108.2 -22.6 -11.4 8.4 151 155 A P G >4 S+ 0 0 107 0, 0.0 3,-1.1 0, 0.0 4,-0.4 0.889 90.8 58.0 -52.5 -42.7 -24.7 -9.7 5.7 152 156 A G G 34 S+ 0 0 25 27,-0.4 4,-0.2 1,-0.3 27,-0.1 0.555 102.3 55.8 -69.0 -9.0 -23.6 -6.3 6.7 153 157 A L G X> S+ 0 0 1 -3,-2.3 4,-1.9 1,-0.1 3,-1.2 0.719 84.9 84.5 -95.3 -19.0 -19.9 -7.3 6.1 154 158 A Q H S+ 0 0 141 -4,-0.4 4,-0.7 1,-0.2 -1,-0.3 0.867 110.0 48.3 -66.7 -29.0 -20.0 -5.1 0.8 156 160 A V H X> S+ 0 0 0 -3,-1.2 3,-1.0 -4,-0.2 4,-0.7 0.928 110.1 50.5 -71.4 -47.6 -16.6 -4.7 2.4 157 161 A V H >< S+ 0 0 4 -4,-1.9 3,-1.0 1,-0.2 4,-0.3 0.905 106.4 58.0 -56.3 -37.8 -15.5 -8.2 1.4 158 162 A D H 3< S+ 0 0 99 -4,-2.3 -1,-0.2 1,-0.3 3,-0.2 0.605 104.9 47.0 -75.8 -16.6 -16.6 -7.5 -2.2 159 163 A V H X< S+ 0 0 26 -3,-1.0 3,-1.8 -4,-0.7 4,-0.5 0.469 84.7 91.8 -97.4 -9.6 -14.3 -4.5 -2.8 160 164 A L G X< S+ 0 0 7 -3,-1.0 3,-1.7 -4,-0.7 -1,-0.2 0.860 74.5 67.8 -53.6 -35.8 -11.2 -6.1 -1.3 161 165 A D G > S+ 0 0 156 -4,-0.3 3,-0.5 1,-0.3 -1,-0.3 0.741 98.4 52.9 -52.3 -30.5 -10.1 -7.3 -4.7 162 166 A S G < S+ 0 0 61 -3,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.460 110.5 43.5 -91.9 -1.4 -9.6 -3.7 -5.8 163 167 A I G < S+ 0 0 0 -3,-1.7 63,-0.3 -4,-0.5 -1,-0.2 -0.218 71.8 139.1-133.7 48.1 -7.3 -2.6 -3.0 164 168 A K < + 0 0 84 -3,-0.5 62,-2.4 61,-0.1 2,-0.2 0.884 59.9 44.3 -62.0 -34.6 -5.2 -5.7 -3.0 165 169 A T S > S- 0 0 13 60,-0.1 3,-1.5 -3,-0.1 -107,-0.3 -0.689 98.9 -73.1-120.1 165.1 -1.8 -4.0 -2.5 166 170 A K T 3 S+ 0 0 110 62,-2.3 64,-0.4 1,-0.3 -107,-0.2 -0.252 114.8 18.7 -59.9 131.6 -0.3 -1.2 -0.3 167 171 A G T 3 S+ 0 0 56 -109,-2.6 -1,-0.3 1,-0.3 2,-0.2 0.354 90.1 126.7 95.3 -15.6 -1.4 2.3 -1.3 168 172 A K < + 0 0 82 -3,-1.5 -110,-2.6 -110,-0.2 -1,-0.3 -0.645 33.3 179.0 -78.0 140.0 -4.5 1.3 -3.4 169 173 A S E -F 57 0B 58 -2,-0.2 2,-0.3 -112,-0.2 -112,-0.2 -0.955 12.2-162.1-138.8 159.2 -7.8 2.9 -2.5 170 174 A A E -F 56 0B 21 -114,-2.5 -114,-2.5 -2,-0.3 2,-0.1 -0.996 34.2-100.1-144.0 140.8 -11.4 2.8 -3.8 171 175 A D E +F 55 0B 147 -2,-0.3 -116,-0.3 -116,-0.2 2,-0.2 -0.415 40.7 180.0 -51.2 136.4 -14.4 5.0 -3.4 172 176 A F + 0 0 19 -118,-2.5 3,-0.4 -106,-0.1 2,-0.2 -0.587 12.2 165.4-144.3 69.2 -16.6 3.4 -0.7 173 177 A T + 0 0 87 -2,-0.2 -119,-0.2 1,-0.2 -121,-0.1 -0.529 52.1 20.2 -94.6 162.2 -19.7 5.6 -0.2 174 178 A N S S+ 0 0 138 -121,-0.6 2,-0.4 1,-0.2 -1,-0.2 0.700 73.7 150.3 57.7 36.6 -23.0 4.9 1.6 175 179 A F - 0 0 10 -3,-0.4 -122,-0.3 -20,-0.0 -1,-0.2 -0.792 38.1-142.3 -94.0 137.7 -21.8 2.0 3.7 176 180 A D > - 0 0 66 -2,-0.4 3,-1.6 1,-0.1 4,-0.1 -0.863 8.8-160.9-106.7 109.9 -23.7 1.7 7.1 177 181 A P G > S+ 0 0 0 0, 0.0 3,-2.1 0, 0.0 -1,-0.1 0.636 80.9 81.4 -65.2 -14.7 -21.6 0.8 10.0 178 182 A R G > S+ 0 0 122 1,-0.3 3,-1.6 -130,-0.2 -26,-0.1 0.779 78.8 70.0 -62.3 -21.3 -24.7 -0.3 12.0 179 183 A G G < S+ 0 0 30 -3,-1.6 -27,-0.4 1,-0.3 -1,-0.3 0.573 93.9 57.5 -75.3 -4.9 -24.6 -3.5 10.1 180 184 A L G < S+ 0 0 0 -3,-2.1 -1,-0.3 -28,-0.1 -2,-0.2 0.343 83.4 100.3 -99.2 -5.8 -21.5 -4.5 12.0 181 185 A L < - 0 0 33 -3,-1.6 4,-0.1 -4,-0.1 -39,-0.0 -0.729 67.8-125.0 -84.5 156.4 -22.8 -4.3 15.6 182 186 A P - 0 0 14 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.080 31.8-100.9 -82.5 176.7 -23.9 -7.2 17.8 183 187 A E S S+ 0 0 183 2,-0.0 2,-0.2 0, 0.0 29,-0.0 0.953 104.2 50.4 -65.8 -49.9 -27.3 -7.4 19.4 184 188 A S - 0 0 31 1,-0.1 26,-0.3 2,-0.1 24,-0.0 -0.654 60.2-158.8 -90.0 151.4 -26.1 -6.4 22.9 185 189 A L + 0 0 58 -2,-0.2 -141,-0.2 24,-0.1 -1,-0.1 0.111 45.6 136.4-112.4 23.1 -23.9 -3.3 23.8 186 190 A D + 0 0 54 22,-0.1 23,-2.5 -143,-0.1 24,-0.5 -0.401 35.4 170.5 -62.8 148.6 -22.7 -4.7 27.2 187 191 A Y E -M 208 0B 2 21,-0.3 68,-2.6 22,-0.1 69,-0.3 -0.923 40.0-125.9-151.3 171.1 -18.9 -4.0 27.4 188 192 A W E -MN 207 254B 14 19,-2.4 19,-2.7 -2,-0.3 2,-0.3 -0.910 29.8-164.5-113.4 151.3 -15.7 -3.9 29.3 189 193 A T E +MN 206 253B 9 64,-2.4 64,-2.4 -2,-0.3 17,-0.2 -0.997 16.9 154.5-139.4 146.2 -13.7 -0.6 29.4 190 194 A Y E -M 205 0B 5 15,-1.3 15,-2.5 -2,-0.3 2,-0.5 -0.974 44.8-100.7-160.7 154.2 -10.0 0.3 30.4 191 195 A P E +M 204 0B 51 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.802 61.0 130.2 -82.3 132.0 -7.6 3.1 29.6 192 196 A G E -M 203 0B 0 11,-3.0 11,-1.4 -2,-0.5 2,-0.2 -0.500 44.1 -94.1-151.3-147.3 -5.0 2.1 27.0 193 197 A S - 0 0 0 8,-0.3 8,-0.2 9,-0.2 2,-0.1 -0.796 43.3 -76.2-134.2 174.1 -3.3 3.0 23.7 194 198 A L - 0 0 32 6,-2.2 -168,-0.4 -2,-0.2 -1,-0.0 -0.496 40.0-136.5 -69.6 156.7 -3.4 2.5 20.0 195 199 A T S S+ 0 0 6 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.359 82.2 56.1-102.0 1.8 -2.1 -0.9 19.1 196 200 A T S > S- 0 0 27 4,-0.1 3,-2.7 46,-0.0 4,-0.3 -0.936 101.6 -44.4-125.2 151.6 0.1 0.1 16.1 197 201 A P T 3 S+ 0 0 13 0, 0.0 -2,-0.1 0, 0.0 -180,-0.0 -0.268 125.3 42.8 -50.2 137.7 2.9 2.7 16.1 198 202 A P T 3 S- 0 0 60 0, 0.0 -179,-0.2 0, 0.0 -3,-0.0 -0.928 83.9-161.0 -83.0 5.0 3.0 5.3 17.3 199 203 A L < - 0 0 0 -3,-2.7 2,-0.1 1,-0.2 -173,-0.1 0.774 19.2-171.9 69.2 30.5 1.3 3.4 20.1 200 204 A L - 0 0 44 -4,-0.3 -6,-2.2 -7,-0.1 2,-2.0 -0.324 26.7-131.5 -69.8 138.8 -0.0 6.7 21.7 201 205 A E S S+ 0 0 45 -8,-0.2 -8,-0.3 1,-0.2 -1,-0.1 -0.538 73.4 110.7 -74.0 48.4 -1.6 6.4 25.1 202 206 A C + 0 0 8 -2,-2.0 -65,-2.8 -67,-0.1 2,-0.4 0.183 49.0 111.5-115.0 7.4 -4.7 8.4 24.2 203 207 A V E -kM 137 192B 0 -11,-1.4 -11,-3.0 -3,-0.3 2,-0.7 -0.759 46.7-164.9-106.3 131.3 -7.5 5.7 24.2 204 208 A T E -kM 138 191B 26 -67,-2.3 -65,-1.8 -2,-0.4 2,-0.4 -0.949 32.3-148.9-101.0 117.9 -10.5 4.8 26.3 205 209 A W E -kM 139 190B 3 -15,-2.5 -15,-1.3 -2,-0.7 2,-0.5 -0.715 17.5-172.4 -88.7 140.1 -11.2 1.3 25.1 206 210 A I E -kM 140 189B 0 -67,-2.3 -65,-2.9 -2,-0.4 2,-0.5 -0.978 9.3-171.6-130.2 105.4 -14.7 -0.1 25.0 207 211 A V E -kM 141 188B 0 -19,-2.7 -19,-2.4 -2,-0.5 2,-0.2 -0.953 19.4-131.8-105.6 116.2 -14.7 -3.8 24.1 208 212 A L E - M 0 187B 0 -67,-2.7 -65,-0.4 -2,-0.5 -21,-0.3 -0.479 4.0-144.5 -75.6 134.6 -18.1 -5.4 23.4 209 213 A K S S+ 0 0 83 -23,-2.5 -22,-0.1 -2,-0.2 -1,-0.1 0.847 81.7 69.9 -65.1 -37.5 -18.8 -8.7 25.2 210 214 A E S S- 0 0 60 -24,-0.5 -67,-0.1 -26,-0.3 -2,-0.1 -0.764 75.1-146.3 -89.0 121.0 -20.8 -10.2 22.4 211 215 A P - 0 0 33 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.254 11.2-127.7 -69.4 164.9 -18.9 -11.2 19.2 212 216 A I E -l 144 0B 4 -69,-2.5 -67,-2.4 -30,-0.1 2,-0.4 -0.821 23.4-126.5-102.7 156.3 -20.4 -11.0 15.7 213 217 A S E -l 145 0B 37 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.877 26.4-178.8-104.6 142.7 -20.2 -14.1 13.5 214 218 A V E -l 146 0B 1 -69,-2.2 -67,-2.5 -2,-0.4 -65,-0.3 -0.941 30.9-104.1-124.3 160.8 -18.7 -14.0 10.0 215 219 A S E > -l 147 0B 11 -2,-0.3 4,-2.3 -69,-0.2 5,-0.3 -0.177 23.9-117.3 -82.4 165.6 -18.5 -16.9 7.6 216 220 A S H > S+ 0 0 44 -69,-0.6 4,-1.8 1,-0.2 -1,-0.1 0.921 117.7 56.0 -64.8 -33.1 -15.3 -18.8 6.8 217 221 A E H > S+ 0 0 124 2,-0.2 4,-1.1 1,-0.2 -1,-0.2 0.814 105.7 51.1 -66.7 -39.5 -15.6 -17.6 3.2 218 222 A Q H > S+ 0 0 3 2,-0.2 4,-0.8 1,-0.2 3,-0.3 0.921 112.1 44.2 -66.1 -45.9 -15.7 -13.9 4.4 219 223 A V H >X S+ 0 0 1 -4,-2.3 4,-1.3 1,-0.2 3,-0.8 0.872 105.4 64.8 -66.6 -33.8 -12.6 -14.1 6.6 220 224 A L H >< S+ 0 0 69 -4,-1.8 3,-0.5 -5,-0.3 -1,-0.2 0.914 97.7 54.8 -54.6 -37.6 -10.8 -16.0 3.9 221 225 A K H >< S+ 0 0 87 -4,-1.1 3,-1.1 -3,-0.3 -1,-0.2 0.777 100.4 58.1 -71.0 -24.1 -11.0 -13.0 1.6 222 226 A F H X< S+ 0 0 2 -4,-0.8 3,-1.3 -3,-0.8 -1,-0.3 0.812 101.3 58.3 -68.4 -33.0 -9.3 -10.8 4.1 223 227 A R T << S+ 0 0 29 -4,-1.3 -1,-0.3 -3,-0.5 -2,-0.2 0.492 93.7 66.5 -76.2 -1.5 -6.3 -13.2 4.1 224 228 A K T < S+ 0 0 125 -3,-1.1 -1,-0.3 -4,-0.2 -2,-0.2 0.468 79.9 103.5 -95.8 -0.2 -5.9 -12.7 0.3 225 229 A L < - 0 0 3 -3,-1.3 12,-2.9 12,-0.3 2,-0.4 -0.231 68.2-126.0 -73.2 172.8 -4.9 -9.0 0.8 226 230 A N B -O 236 0C 3 -62,-2.4 10,-0.2 -63,-0.3 -166,-0.2 -0.948 16.4-158.5-125.5 142.5 -1.2 -8.0 0.5 227 231 A F S S+ 0 0 40 8,-2.1 -1,-0.1 -2,-0.4 9,-0.1 0.759 80.0 74.4 -78.6 -31.6 1.2 -6.1 2.8 228 232 A N S S- 0 0 6 7,-0.6 -62,-2.3 1,-0.1 -2,-0.1 -0.301 85.9-106.8 -77.7 172.3 3.4 -5.3 -0.2 229 233 A G > - 0 0 5 -64,-0.3 3,-1.3 1,-0.2 -1,-0.1 -0.404 51.3 -73.3 -93.4 168.7 2.9 -2.8 -3.0 230 234 A E T 3 S+ 0 0 139 -64,-0.4 -1,-0.2 1,-0.3 0, 0.0 -0.193 120.1 23.0 -57.0 139.0 2.1 -3.6 -6.6 231 235 A G T 3 S+ 0 0 84 1,-0.3 -1,-0.3 -3,-0.1 -2,-0.1 0.708 101.5 107.4 75.5 17.1 5.0 -5.2 -8.5 232 236 A E S < S- 0 0 101 -3,-1.3 -1,-0.3 1,-0.1 -4,-0.1 -0.821 85.7 -75.1-122.0 159.8 6.8 -6.3 -5.3 233 237 A P - 0 0 106 0, 0.0 2,-0.4 0, 0.0 -5,-0.1 -0.283 61.0-105.4 -53.4 135.2 7.2 -9.9 -4.0 234 238 A E + 0 0 114 -7,-0.1 2,-0.4 -6,-0.1 -8,-0.0 -0.614 39.8 174.5 -72.9 124.8 3.9 -11.0 -2.5 235 239 A E - 0 0 102 -2,-0.4 -8,-2.1 -3,-0.1 -7,-0.6 -0.998 32.2-127.1-128.9 110.4 3.5 -11.2 1.3 236 240 A L B -O 226 0C 89 -2,-0.4 2,-1.3 -10,-0.2 -10,-0.3 -0.411 20.3-119.3 -61.0 144.6 -0.1 -12.1 2.4 237 241 A M + 0 0 0 -12,-2.9 -12,-0.3 -15,-0.2 2,-0.3 -0.735 64.0 131.7 -88.3 94.9 -1.6 -9.7 4.9 238 242 A V + 0 0 34 -2,-1.3 -143,-0.2 1,-0.2 -142,-0.2 -0.971 51.7 25.8-140.3 159.9 -2.2 -12.1 7.8 239 243 A D + 0 0 43 -145,-0.7 2,-0.3 -2,-0.3 -144,-0.2 0.949 63.1 158.2 55.4 48.4 -1.5 -12.0 11.5 240 244 A N + 0 0 2 -146,-1.3 2,-0.4 -3,-0.1 -1,-0.2 -0.326 35.5 113.8 -96.3 51.1 -1.5 -8.2 11.8 241 245 A W - 0 0 47 -2,-0.3 -139,-0.1 -148,-0.1 -138,-0.1 -0.889 62.6-130.5-117.2 156.6 -2.3 -8.3 15.5 242 246 A R - 0 0 5 -2,-0.4 3,-0.1 1,-0.1 -2,-0.1 -0.770 31.0-113.8-100.8 132.9 -0.2 -7.3 18.5 243 247 A P - 0 0 59 0, 0.0 -140,-0.1 0, 0.0 -1,-0.1 -0.251 45.4 -80.3 -62.9 153.4 0.2 -9.7 21.4 244 248 A A - 0 0 51 -216,-0.1 -216,-0.2 -141,-0.1 -218,-0.1 -0.238 47.8-148.9 -61.4 141.9 -1.3 -8.9 24.8 245 249 A Q - 0 0 45 -218,-2.5 -216,-0.4 -220,-0.1 -1,-0.1 -0.807 30.7 -73.2-107.6 166.7 0.6 -6.5 27.1 246 250 A P - 0 0 80 0, 0.0 -221,-0.2 0, 0.0 -1,-0.1 -0.190 29.6-146.0 -62.7 132.2 0.9 -6.1 30.8 247 251 A L + 0 0 55 1,-0.2 -219,-0.0 -223,-0.1 -2,-0.0 0.823 37.3 169.4 -67.1 -32.3 -2.1 -4.7 32.6 248 252 A K - 0 0 93 1,-0.2 2,-1.5 -224,-0.0 -1,-0.2 -0.295 64.5 -5.9 54.3-132.7 0.2 -2.9 35.1 249 253 A N S S+ 0 0 160 -226,-0.3 2,-0.4 2,-0.0 -1,-0.2 -0.444 107.7 112.3 -84.9 48.1 -1.6 -0.5 37.3 250 254 A R - 0 0 32 -2,-1.5 2,-0.4 -60,-0.0 -3,-0.0 -0.973 52.1-147.9-124.4 155.0 -5.0 -0.7 35.6 251 255 A Q - 0 0 102 -2,-0.4 2,-0.5 -216,-0.0 -216,-0.1 -0.930 13.2-141.7-111.8 131.0 -8.5 -1.9 36.4 252 256 A I - 0 0 8 -2,-0.4 -216,-1.7 -218,-0.2 2,-0.4 -0.847 20.3-158.9 -90.1 130.2 -10.9 -3.4 33.8 253 257 A K E -cN 36 189B 51 -64,-2.4 -64,-2.4 -2,-0.5 2,-0.3 -0.865 2.1-151.4-106.3 147.0 -14.6 -2.3 34.4 254 258 A A E -cN 37 188B 7 -218,-2.2 -216,-2.1 -2,-0.4 -66,-0.2 -0.904 12.5-149.6-112.9 148.3 -17.6 -4.2 33.1 255 259 A S S S+ 0 0 30 -68,-2.6 2,-0.3 -2,-0.3 -67,-0.1 0.337 81.2 59.7 -89.3 3.0 -21.0 -2.5 32.3 256 260 A F 0 0 33 -69,-0.3 -2,-0.1 1,-0.2 -218,-0.0 -0.927 360.0 360.0-139.8 149.3 -22.8 -5.8 33.2 257 261 A K 0 0 226 -2,-0.3 -1,-0.2 -220,-0.1 -220,-0.1 0.960 360.0 360.0 -79.5 360.0 -23.2 -8.0 36.2