==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=4-OCT-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GENE REGULATION 01-AUG-13 4C0G . COMPND 2 MOLECULE: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.BOLAND,Y.CHEN,T.RAISCH,S.JONAS,E.IZAURRALDE,O.WEICHENRIEDE . 563 6 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 32504.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 397 70.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 143 25.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 12 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 6 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 39 6.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 48 8.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 137 24.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 20 3.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 1 2 0 0 0 6 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 5 5 8 4 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 1 3 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 659 A T > 0 0 128 0, 0.0 4,-0.7 0, 0.0 27,-0.0 0.000 360.0 360.0 360.0 170.2 -35.4 -35.0 17.9 2 660 A V H > + 0 0 83 1,-0.2 4,-0.8 2,-0.2 0, 0.0 0.798 360.0 58.2 -85.3 -30.8 -37.6 -37.6 19.6 3 661 A E H > S+ 0 0 120 1,-0.2 4,-1.0 2,-0.2 -1,-0.2 0.766 97.2 62.8 -74.0 -26.4 -36.5 -40.6 17.6 4 662 A F H >> S+ 0 0 30 1,-0.2 3,-1.7 2,-0.2 4,-1.3 0.973 101.8 47.7 -62.8 -55.5 -32.8 -40.2 18.6 5 663 A Y H 3< S+ 0 0 30 -4,-0.7 -1,-0.2 1,-0.3 -2,-0.2 0.772 103.1 67.1 -58.0 -24.7 -33.4 -40.8 22.4 6 664 A Q H 3< S+ 0 0 88 -4,-0.8 -1,-0.3 1,-0.2 -2,-0.2 0.878 101.2 47.4 -60.0 -39.3 -35.5 -43.8 21.2 7 665 A R H << S+ 0 0 154 -3,-1.7 -2,-0.2 -4,-1.0 -1,-0.2 0.876 90.2 101.5 -69.9 -40.5 -32.2 -45.4 20.0 8 666 A L S < S- 0 0 3 -4,-1.3 294,-0.0 1,-0.1 5,-0.0 -0.042 82.7-104.0 -51.1 145.1 -30.2 -44.7 23.2 9 667 A S > - 0 0 41 1,-0.1 4,-1.7 4,-0.0 3,-0.2 -0.244 30.7-112.9 -61.2 160.5 -29.7 -47.5 25.6 10 668 A T H > S+ 0 0 36 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.909 117.6 57.5 -64.3 -41.6 -31.9 -47.3 28.7 11 669 A E H > S+ 0 0 37 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.830 106.1 50.6 -59.1 -32.6 -28.8 -46.8 30.9 12 670 A T H > S+ 0 0 0 -3,-0.2 4,-2.4 2,-0.2 -1,-0.2 0.892 108.1 51.7 -71.9 -39.8 -28.1 -43.7 28.8 13 671 A L H X S+ 0 0 0 -4,-1.7 4,-2.5 2,-0.2 -2,-0.2 0.903 109.1 51.6 -62.5 -40.3 -31.6 -42.4 29.2 14 672 A F H X S+ 0 0 3 -4,-2.5 4,-2.5 2,-0.2 5,-0.3 0.936 108.9 49.5 -62.9 -47.1 -31.3 -42.8 33.0 15 673 A F H X S+ 0 0 6 -4,-1.9 4,-2.2 1,-0.2 5,-0.3 0.934 112.8 47.5 -55.9 -48.8 -28.0 -40.9 33.1 16 674 A I H X S+ 0 0 0 -4,-2.4 4,-1.6 1,-0.2 -1,-0.2 0.913 113.4 49.3 -56.3 -44.4 -29.6 -38.1 31.1 17 675 A F H < S+ 0 0 29 -4,-2.5 -2,-0.2 1,-0.2 -1,-0.2 0.854 118.6 35.4 -67.7 -38.4 -32.6 -38.1 33.3 18 676 A Y H < S+ 0 0 50 -4,-2.5 3,-0.2 -5,-0.1 -1,-0.2 0.726 125.9 34.5 -91.1 -22.9 -30.8 -37.9 36.6 19 677 A Y H < S+ 0 0 88 -4,-2.2 2,-0.2 -5,-0.3 -3,-0.2 0.544 112.2 53.6-116.6 -10.0 -27.8 -35.7 35.8 20 678 A L S >< S+ 0 0 34 -4,-1.6 3,-0.6 -5,-0.3 6,-0.5 -0.555 76.8 177.2-120.7 67.1 -29.1 -33.2 33.3 21 679 A E T 3 + 0 0 158 1,-0.2 3,-0.1 -3,-0.2 4,-0.1 -0.315 60.0 18.5 -73.5 152.9 -32.1 -31.8 35.2 22 680 A G T 3 S+ 0 0 77 1,-0.2 2,-0.3 2,-0.1 -1,-0.2 0.872 100.6 118.8 56.7 39.7 -34.2 -29.0 33.8 23 681 A T S <> S- 0 0 60 -3,-0.6 4,-1.6 1,-0.1 -1,-0.2 -0.913 77.0-116.3-131.3 159.7 -33.0 -29.6 30.3 24 682 A K H >> S+ 0 0 150 -2,-0.3 4,-1.8 1,-0.2 3,-0.5 0.965 113.3 59.8 -56.1 -51.8 -34.5 -30.5 27.0 25 683 A A H 3> S+ 0 0 15 1,-0.3 4,-1.9 2,-0.2 -1,-0.2 0.861 104.4 48.7 -46.9 -48.7 -32.5 -33.8 26.9 26 684 A Q H 3> S+ 0 0 49 -6,-0.5 4,-2.8 1,-0.2 -1,-0.3 0.919 107.5 57.3 -56.2 -44.6 -34.1 -35.0 30.2 27 685 A Y H <>S+ 0 0 0 -4,-2.6 5,-2.0 1,-0.2 3,-1.0 0.922 107.9 54.4 -66.5 -46.3 -38.6 -44.3 28.6 34 692 A K H ><5S+ 0 0 103 -4,-2.0 3,-1.9 1,-0.3 -1,-0.2 0.887 105.2 54.2 -54.9 -40.8 -42.4 -44.1 28.9 35 693 A K H 3<5S+ 0 0 152 -4,-2.3 -1,-0.3 1,-0.3 -2,-0.2 0.748 103.6 56.4 -67.7 -23.0 -42.7 -45.4 25.3 36 694 A Q T <<5S- 0 0 65 -3,-1.0 -1,-0.3 -4,-0.8 -2,-0.2 0.258 127.5-104.1 -88.6 10.3 -40.5 -48.3 26.5 37 695 A S T < 5S+ 0 0 78 -3,-1.9 13,-0.4 1,-0.3 2,-0.4 0.763 75.5 140.7 72.9 27.7 -43.2 -49.0 29.2 38 696 A W < - 0 0 5 -5,-2.0 2,-0.4 11,-0.1 -1,-0.3 -0.808 32.8-162.3 -92.4 143.2 -41.2 -47.5 32.1 39 697 A R E -A 48 0A 108 9,-2.6 9,-3.0 -2,-0.4 2,-0.5 -0.976 16.7-121.9-127.8 145.9 -43.1 -45.5 34.6 40 698 A F E -A 47 0A 20 -2,-0.4 2,-0.9 7,-0.2 50,-0.3 -0.736 11.6-146.4 -91.9 122.0 -41.8 -43.1 37.2 41 699 A H E >> -A 46 0A 1 5,-2.6 4,-2.3 -2,-0.5 5,-0.7 -0.774 11.3-155.3 -84.1 107.1 -42.5 -43.7 40.9 42 700 A T T 45S+ 0 0 55 46,-2.6 -1,-0.1 -2,-0.9 47,-0.1 0.567 87.6 40.0 -68.2 -9.7 -42.8 -40.1 42.2 43 701 A K T 45S+ 0 0 116 45,-0.2 -1,-0.2 3,-0.1 -2,-0.0 0.849 119.3 38.5 -99.3 -61.2 -41.9 -41.2 45.7 44 702 A Y T 45S- 0 0 110 2,-0.1 -2,-0.2 44,-0.1 3,-0.1 0.738 100.2-138.4 -61.1 -23.0 -39.1 -43.8 45.4 45 703 A X T <5 + 0 0 100 -4,-2.3 2,-0.3 1,-0.3 26,-0.2 0.874 60.8 116.3 67.2 38.8 -37.9 -41.6 42.6 46 704 A X E < -A 41 0A 25 -5,-0.7 -5,-2.6 24,-0.1 2,-0.4 -0.954 67.3-111.5-137.4 155.0 -37.1 -44.5 40.3 47 705 A W E -AB 40 69A 2 22,-0.5 22,-1.6 -2,-0.3 2,-0.3 -0.742 33.9-167.7 -89.8 132.5 -38.2 -45.9 37.0 48 706 A F E -AB 39 68A 7 -9,-3.0 -9,-2.6 -2,-0.4 2,-0.3 -0.808 10.3-173.1-116.9 157.1 -40.2 -49.2 37.0 49 707 A Q E - B 0 67A 49 18,-1.7 18,-2.2 -2,-0.3 -11,-0.1 -0.948 35.7-104.7-150.3 128.8 -41.2 -51.7 34.4 50 708 A R E - B 0 66A 121 -13,-0.4 16,-0.3 -2,-0.3 3,-0.1 -0.290 23.5-164.2 -51.0 125.8 -43.5 -54.7 34.7 51 709 A H S S- 0 0 97 14,-2.4 2,-0.2 1,-0.2 15,-0.2 0.896 75.2 -17.9 -77.5 -44.3 -41.4 -57.9 34.6 52 710 A E S S- 0 0 119 13,-0.9 -1,-0.2 -3,-0.0 13,-0.1 -0.798 102.1 -49.3-143.3-173.5 -44.4 -59.9 33.9 53 711 A E - 0 0 161 -2,-0.2 12,-0.2 -3,-0.1 -2,-0.0 -0.414 66.8-108.8 -64.4 136.0 -48.2 -59.5 34.2 54 712 A P - 0 0 9 0, 0.0 10,-0.3 0, 0.0 3,-0.1 -0.153 13.3-134.6 -60.0 160.1 -49.3 -58.2 37.7 55 713 A K S S+ 0 0 79 8,-2.6 2,-0.4 1,-0.3 9,-0.2 0.956 87.3 16.3 -75.4 -60.7 -51.0 -60.5 40.1 56 714 A T E -C 63 0A 61 7,-1.0 7,-2.3 -3,-0.0 2,-0.4 -0.904 62.0-175.5-119.5 142.5 -53.7 -58.0 41.2 57 715 A I E +C 62 0A 85 -2,-0.4 5,-0.2 5,-0.2 2,-0.2 -0.961 9.6 165.9-135.9 120.1 -54.9 -54.8 39.6 58 716 A T - 0 0 54 3,-3.0 -2,-0.0 -2,-0.4 0, 0.0 -0.470 55.0 -93.1-108.9-169.9 -57.5 -52.4 41.1 59 717 A D S S+ 0 0 146 -2,-0.2 3,-0.1 1,-0.2 -2,-0.0 0.672 124.9 39.9 -77.1 -16.8 -58.3 -48.9 40.0 60 718 A E S S- 0 0 120 1,-0.3 26,-2.6 26,-0.0 27,-0.5 0.690 123.9 -4.7-107.7 -24.8 -55.9 -47.6 42.6 61 719 A F E - D 0 85A 67 24,-0.3 -3,-3.0 25,-0.1 2,-0.3 -0.982 49.1-143.9-160.1 168.4 -52.9 -49.9 42.5 62 720 A E E -CD 57 84A 15 22,-1.5 22,-2.6 -2,-0.3 2,-0.4 -0.959 13.4-155.4-134.3 155.6 -51.3 -53.1 41.0 63 721 A Q E +CD 56 83A 67 -7,-2.3 -8,-2.6 -2,-0.3 -7,-1.0 -0.993 39.3 87.7-133.3 144.8 -49.0 -55.6 42.6 64 722 A G E S- D 0 82A 10 18,-1.9 18,-2.5 -2,-0.4 2,-0.4 -0.962 72.2 -33.6 168.6-151.3 -46.5 -58.0 41.0 65 723 A T E + 0 0 17 -2,-0.3 -14,-2.4 -12,-0.2 -13,-0.9 -0.834 53.9 172.5-107.1 138.3 -42.9 -58.3 39.9 66 724 A Y E -BD 50 79A 5 13,-2.4 13,-2.9 -2,-0.4 2,-0.4 -0.968 28.8-138.1-139.7 152.5 -40.9 -55.4 38.4 67 725 A I E +BD 49 78A 22 -18,-2.2 -18,-1.7 -2,-0.3 2,-0.3 -0.912 32.1 179.1-103.1 143.4 -37.4 -54.4 37.4 68 726 A Y E -BD 48 77A 39 9,-2.0 9,-3.6 -2,-0.4 2,-0.7 -0.955 30.4-119.0-141.1 158.5 -36.3 -51.0 38.4 69 727 A F E -BD 47 76A 9 -22,-1.6 2,-0.8 -2,-0.3 -22,-0.5 -0.891 21.6-156.0-104.5 110.6 -33.3 -48.8 38.0 70 728 A D E >> - D 0 75A 15 5,-2.0 5,-1.4 -2,-0.7 4,-1.0 -0.761 3.6-166.3 -87.1 109.5 -31.8 -47.8 41.4 71 729 A Y T 45S+ 0 0 79 -2,-0.8 -1,-0.2 1,-0.2 5,-0.1 0.708 85.6 61.3 -71.5 -19.7 -29.8 -44.6 40.8 72 730 A E T 45S+ 0 0 149 1,-0.2 -1,-0.2 3,-0.1 -2,-0.0 0.869 118.7 27.5 -73.6 -37.0 -28.1 -44.9 44.2 73 731 A K T 45S- 0 0 107 -3,-0.4 -2,-0.2 2,-0.2 -1,-0.2 0.479 103.6-135.6 -95.0 -6.0 -26.5 -48.3 43.1 74 732 A W T <5 + 0 0 28 -4,-1.0 2,-0.3 1,-0.2 -3,-0.2 0.950 66.4 103.4 41.1 64.1 -26.6 -47.2 39.5 75 733 A G E -D 61 0A 71 -2,-1.0 3,-2.0 -24,-0.2 -24,-0.3 -0.628 11.2-141.7 -76.4 126.4 -49.8 -47.4 44.0 86 744 A Y G > S+ 0 0 63 -26,-2.6 3,-1.8 -2,-0.4 -25,-0.1 0.665 96.0 72.8 -65.0 -17.9 -51.1 -45.3 41.1 87 745 A R G 3 S+ 0 0 168 -27,-0.5 -1,-0.3 1,-0.3 -26,-0.1 0.711 93.0 57.0 -70.3 -17.5 -51.2 -42.1 43.3 88 746 A Y G < S+ 0 0 47 -3,-2.0 -46,-2.6 2,-0.1 -1,-0.3 0.180 92.0 101.1 -92.7 15.2 -47.4 -42.2 43.0 89 747 A L < 0 0 69 -3,-1.8 -48,-0.1 -48,-0.2 -50,-0.0 -0.697 360.0 360.0 -98.6 152.7 -47.9 -42.1 39.2 90 748 A E 0 0 171 -50,-0.3 -50,-0.1 -2,-0.3 -2,-0.1 -0.764 360.0 360.0 -89.8 360.0 -47.4 -39.0 37.1 91 !* 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 92 655 B A 0 0 82 0, 0.0 2,-0.5 0, 0.0 3,-0.0 0.000 360.0 360.0 360.0-169.3 -19.3 8.8 17.1 93 656 B H > - 0 0 130 1,-0.1 3,-2.2 2,-0.0 6,-0.4 -0.723 360.0-140.6 -89.3 126.3 -18.5 12.5 17.6 94 657 B S T 3 S+ 0 0 45 -2,-0.5 -1,-0.1 1,-0.3 6,-0.1 0.763 103.1 65.3 -56.6 -26.1 -18.9 14.7 14.5 95 658 B D T 3 S+ 0 0 44 4,-0.1 -1,-0.3 3,-0.0 2,-0.2 0.768 93.4 80.5 -65.0 -25.6 -15.7 16.6 15.6 96 659 B T S X> S- 0 0 43 -3,-2.2 3,-0.6 1,-0.1 4,-0.5 -0.523 76.6-141.1 -85.3 148.8 -13.9 13.3 15.0 97 660 B V H 3> S+ 0 0 39 1,-0.2 4,-1.0 -2,-0.2 3,-0.4 0.704 101.4 71.7 -74.1 -21.4 -12.8 12.0 11.6 98 661 B E H 34 S+ 0 0 125 1,-0.2 4,-0.3 2,-0.2 -1,-0.2 0.724 90.6 60.0 -67.7 -20.7 -13.8 8.6 12.8 99 662 B F H X4 S+ 0 0 8 -3,-0.6 3,-1.0 -6,-0.4 4,-0.3 0.866 102.2 49.6 -75.2 -38.0 -17.4 9.7 12.5 100 663 B Y H >< S+ 0 0 14 -4,-0.5 3,-0.9 -3,-0.4 -1,-0.2 0.719 97.9 68.7 -76.1 -20.3 -17.2 10.4 8.8 101 664 B Q T 3< S+ 0 0 43 -4,-1.0 -1,-0.2 1,-0.2 -2,-0.2 0.670 94.0 60.0 -69.9 -15.8 -15.6 7.0 8.2 102 665 B R T < S+ 0 0 49 -3,-1.0 -1,-0.2 -4,-0.3 -2,-0.2 0.709 91.9 87.5 -80.0 -22.6 -19.1 5.6 9.1 103 666 B L S < S- 0 0 3 -3,-0.9 293,-0.1 -4,-0.3 2,-0.0 -0.353 84.8-100.7 -86.0 158.1 -20.8 7.4 6.3 104 667 B S > - 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