==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=29-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER SIGNALING PROTEIN/RECEPTOR 26-OCT-05 2C5D . COMPND 2 MOLECULE: GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR T.SASAKI,P.G.KNYAZEV,N.J.CLOUT,Y.CHEBURKIN,W.GOEHRING, . 1142 8 10 8 2 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 51143.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 705 61.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 27 2.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 434 38.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 24 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 2 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 108 9.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 68 6.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 25 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 2 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 14 10 8 18 6 14 6 4 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 4 0 0 0 2 0 4 0 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 279 A D 0 0 211 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 127.2 44.1 86.8 100.3 2 280 A I - 0 0 89 228,-0.0 228,-0.0 230,-0.0 0, 0.0 -0.755 360.0-160.7 -94.6 142.6 45.4 87.5 96.7 3 281 A L - 0 0 129 -2,-0.3 2,-0.8 0, 0.0 228,-0.5 -0.884 29.9 -91.4-125.5 156.0 48.3 85.5 95.5 4 282 A P - 0 0 66 0, 0.0 226,-0.2 0, 0.0 272,-0.0 -0.505 34.1-177.0 -66.4 105.0 50.9 85.9 92.7 5 283 A a S S+ 0 0 55 -2,-0.8 225,-0.2 224,-0.4 224,-0.0 0.623 83.6 32.1 -78.6 -12.3 49.5 84.0 89.7 6 284 A V S S- 0 0 14 223,-0.9 -1,-0.3 271,-0.1 271,-0.1 -0.715 84.0-163.1-145.4 87.7 52.6 84.8 87.8 7 285 A P - 0 0 64 0, 0.0 373,-0.4 0, 0.0 2,-0.2 -0.336 8.3-139.7 -73.1 154.9 55.8 84.9 90.0 8 286 A F - 0 0 7 371,-0.2 2,-2.1 221,-0.1 371,-0.2 -0.698 32.5 -90.9-110.3 164.2 59.0 86.5 88.9 9 287 A S - 0 0 33 369,-3.2 2,-2.7 -2,-0.2 186,-0.3 -0.520 43.4-178.4 -76.5 79.5 62.7 85.4 89.4 10 288 A V + 0 0 88 -2,-2.1 2,-0.7 367,-0.1 -1,-0.1 -0.346 28.0 145.6 -76.8 58.6 63.2 87.2 92.6 11 289 A A - 0 0 50 -2,-2.7 183,-3.0 184,-0.1 184,-0.4 -0.895 31.1-163.3-104.5 114.1 66.8 86.0 92.6 12 290 A K B -A 193 0A 69 -2,-0.7 2,-0.2 181,-0.2 181,-0.2 -0.019 17.7-124.2 -80.4-168.8 69.3 88.4 94.1 13 291 A S > - 0 0 21 179,-0.6 3,-3.4 175,-0.2 179,-0.5 -0.693 11.3-161.4-146.1 86.5 73.1 88.3 93.7 14 292 A V T 3 S+ 0 0 67 1,-0.3 173,-0.1 -2,-0.2 -1,-0.1 0.560 90.0 58.3 -42.6 -17.9 75.0 88.3 97.0 15 293 A K T 3 S+ 0 0 132 177,-0.1 154,-0.5 170,-0.1 -1,-0.3 0.471 97.9 78.3 -96.2 -2.4 78.2 89.4 95.3 16 294 A S < - 0 0 2 -3,-3.4 2,-0.3 152,-0.1 152,-0.2 -0.250 66.7-135.5 -99.4-174.6 76.7 92.6 93.9 17 295 A L E -B 167 0B 1 150,-1.6 150,-1.9 174,-0.1 2,-0.6 -0.953 11.2-142.1-147.1 122.3 75.8 96.1 95.1 18 296 A Y E > -B 166 0B 18 172,-3.1 3,-0.5 -2,-0.3 148,-0.2 -0.755 11.4-172.8 -89.6 119.7 72.6 98.0 94.4 19 297 A L T 3 S+ 0 0 6 146,-2.5 3,-0.4 -2,-0.6 144,-0.3 0.671 81.9 57.7 -83.6 -20.3 73.2 101.7 93.9 20 298 A G T 3 + 0 0 8 145,-0.5 -1,-0.2 1,-0.2 353,-0.1 0.328 68.4 115.4 -93.8 12.9 69.5 102.6 93.8 21 299 A R S < S+ 0 0 10 -3,-0.5 2,-0.6 1,-0.1 -1,-0.2 0.838 71.5 51.9 -50.1 -40.3 68.7 101.3 97.2 22 300 A M > - 0 0 7 -3,-0.4 3,-1.4 4,-0.3 -1,-0.1 -0.888 59.8-162.7-112.6 122.3 67.8 104.6 98.7 23 301 A F T 3 S+ 0 0 28 -2,-0.6 -1,-0.1 1,-0.3 139,-0.1 0.738 87.0 74.9 -65.1 -24.5 65.3 107.1 97.1 24 302 A S T 3 S- 0 0 48 799,-0.4 -1,-0.3 1,-0.1 799,-0.0 0.371 106.0-122.4 -72.2 5.6 66.7 109.8 99.2 25 303 A G < + 0 0 17 -3,-1.4 123,-0.6 1,-0.2 -2,-0.1 0.639 59.8 150.4 63.0 15.4 69.8 110.0 97.0 26 304 A T - 0 0 7 797,-0.3 -4,-0.3 121,-0.1 -1,-0.2 -0.542 58.5 -97.4 -75.8 145.7 72.1 109.3 100.0 27 305 A P - 0 0 6 0, 0.0 119,-0.2 0, 0.0 120,-0.1 -0.421 22.8-139.9 -65.6 141.7 75.2 107.4 99.0 28 306 A V S S+ 0 0 0 117,-1.6 2,-0.3 1,-0.2 118,-0.1 0.589 88.2 20.4 -76.2 -12.7 74.9 103.7 99.6 29 307 A I E -M 145 0C 0 116,-0.7 116,-2.3 790,-0.2 2,-0.4 -0.966 65.0-164.9-156.9 139.3 78.5 103.7 100.8 30 308 A R E -MN 144 818C 48 788,-2.4 788,-3.4 -2,-0.3 2,-0.4 -0.990 6.9-169.3-132.0 125.4 80.9 106.3 102.1 31 309 A L E -MN 143 817C 5 112,-3.2 112,-2.6 -2,-0.4 2,-0.4 -0.883 4.2-164.3-112.7 147.1 84.6 105.8 102.4 32 310 A R E -MN 142 816C 74 784,-2.0 784,-2.0 -2,-0.4 2,-0.5 -0.967 10.1-157.8-132.8 114.1 87.0 108.1 104.2 33 311 A F E +MN 141 815C 7 108,-3.2 108,-1.4 -2,-0.4 2,-0.5 -0.838 14.1 179.8-102.5 127.5 90.7 107.8 103.5 34 312 A K E +MN 140 814C 40 780,-2.5 780,-1.9 -2,-0.5 2,-0.4 -0.995 17.8 177.1-119.8 120.5 93.5 108.9 105.8 35 313 A R E -M 139 0C 14 104,-2.5 104,-2.9 -2,-0.5 4,-0.1 -0.971 33.2-140.6-131.2 145.2 96.9 108.2 104.3 36 314 A L S S+ 0 0 64 -2,-0.4 -1,-0.1 102,-0.2 3,-0.1 0.821 85.6 29.7 -72.2 -37.1 100.4 108.9 105.5 37 315 A Q S S- 0 0 142 1,-0.1 102,-0.1 102,-0.1 101,-0.0 -0.823 104.9 -65.5-124.2 164.0 101.9 109.8 102.1 38 316 A P - 0 0 92 0, 0.0 2,-0.4 0, 0.0 -1,-0.1 -0.086 57.1-157.7 -43.4 141.9 100.7 111.3 98.8 39 317 A T - 0 0 31 101,-0.1 93,-0.5 -4,-0.1 2,-0.4 -0.987 15.9-138.2-139.4 133.1 98.2 108.9 97.2 40 318 A R - 0 0 129 -2,-0.4 2,-0.3 91,-0.1 69,-0.1 -0.679 29.2-125.0 -84.0 133.0 96.9 108.4 93.6 41 319 A L + 0 0 1 -2,-0.4 67,-1.7 18,-0.0 2,-0.3 -0.619 35.8 169.0 -79.6 137.2 93.2 107.8 93.4 42 320 A V E +C 107 0B 22 -2,-0.3 131,-3.0 65,-0.2 2,-0.4 -0.884 5.1 169.5-151.9 115.7 92.1 104.7 91.6 43 321 A A E +CD 106 172B 0 63,-2.7 63,-1.9 -2,-0.3 2,-0.3 -0.976 4.1 167.6-127.7 143.0 88.6 103.2 91.5 44 322 A E E +CD 105 171B 66 127,-1.2 127,-1.6 -2,-0.4 2,-0.3 -0.980 5.9 151.9-150.9 148.7 87.5 100.4 89.3 45 323 A F E -C 104 0B 0 59,-2.1 59,-2.5 -2,-0.3 2,-0.4 -0.974 44.0-103.9-172.0 162.1 84.4 98.3 89.2 46 324 A D E -CD 103 168B 30 122,-3.3 122,-1.9 -2,-0.3 2,-0.4 -0.819 43.3-170.5 -96.3 139.4 82.0 96.2 87.1 47 325 A F E - D 0 167B 0 55,-1.9 2,-0.4 -2,-0.4 55,-0.4 -0.996 15.9-176.1-141.3 136.0 78.8 98.1 86.4 48 326 A R E + D 0 166B 18 118,-2.0 118,-2.9 -2,-0.4 2,-0.3 -0.993 21.1 142.4-132.5 132.1 75.4 97.2 84.8 49 327 A T E - D 0 165B 4 47,-0.5 50,-2.0 51,-0.4 51,-0.2 -0.999 42.0-167.0-165.5 161.9 72.4 99.5 84.2 50 328 A F + 0 0 26 114,-0.7 47,-0.1 -2,-0.3 -1,-0.1 0.600 66.6 106.6-116.6 -36.0 69.5 100.7 82.1 51 329 A D - 0 0 0 113,-0.7 48,-0.1 1,-0.2 323,-0.0 -0.249 59.5-155.2 -49.3 123.9 69.0 104.0 84.0 52 330 A P S S+ 0 0 47 0, 0.0 23,-3.5 0, 0.0 2,-0.4 0.613 74.3 44.4 -79.0 -17.2 70.3 106.7 81.6 53 331 A E S S+ 0 0 56 20,-0.2 111,-0.3 21,-0.2 2,-0.3 -0.996 73.0 100.2-136.0 137.9 71.0 109.2 84.4 54 332 A G E -O 72 0C 0 18,-3.0 18,-3.1 -2,-0.4 2,-0.6 -0.960 60.5 -85.1 169.1 173.8 72.7 108.8 87.7 55 333 A I E -O 71 0C 0 106,-2.1 16,-0.2 -2,-0.3 108,-0.2 -0.935 26.2-178.8-111.7 122.0 75.7 109.2 89.9 56 334 A L E - 0 0 0 14,-1.8 90,-3.5 -2,-0.6 2,-0.3 0.961 65.2 -21.2 -78.8 -61.8 78.3 106.5 89.9 57 335 A L E -OP 70 145C 0 13,-1.7 13,-2.4 88,-0.3 2,-0.4 -0.998 45.0-146.2-156.9 151.9 80.8 107.9 92.4 58 336 A F E +OP 69 144C 1 86,-3.0 86,-1.8 -2,-0.3 2,-0.3 -0.909 21.4 177.5-113.6 144.4 82.1 111.0 94.2 59 337 A A E +OP 68 143C 0 9,-2.3 9,-2.4 -2,-0.4 2,-0.3 -0.948 36.3 47.0-150.8 124.0 85.7 111.4 95.1 60 338 A G E S-OP 67 142C 0 82,-2.5 82,-2.6 -2,-0.3 7,-0.3 -0.995 75.2 -60.8 150.5-154.8 87.4 114.3 96.7 61 339 A G S S- 0 0 24 5,-2.4 2,-0.2 -2,-0.3 6,-0.1 0.391 81.5 -9.4-101.2-127.6 87.2 116.8 99.5 62 340 A H S > S- 0 0 123 1,-0.1 3,-3.2 4,-0.0 4,-0.3 -0.513 70.3-104.4 -80.2 144.9 84.7 119.5 100.5 63 341 A Q T 3 S+ 0 0 52 1,-0.3 4,-0.1 -2,-0.2 -1,-0.1 0.744 120.6 31.1 -33.0 -45.5 81.9 120.6 98.2 64 342 A D T 3 S+ 0 0 91 2,-0.1 -1,-0.3 20,-0.1 21,-0.2 0.087 112.4 67.4-110.8 25.8 83.6 123.9 97.2 65 343 A S S < S- 0 0 31 -3,-3.2 19,-2.6 19,-0.1 20,-0.4 0.698 109.5 -48.8-101.8 -94.3 87.2 122.7 97.5 66 344 A T E S+ Q 0 83C 2 -4,-0.3 -5,-2.4 17,-0.3 2,-0.3 -0.920 71.0 131.4-154.5 124.4 88.3 120.1 94.9 67 345 A W E -OQ 60 82C 0 15,-2.3 15,-2.2 -2,-0.3 2,-0.3 -0.935 35.8-132.8-157.8 176.5 86.5 116.9 93.9 68 346 A I E -OQ 59 81C 0 -9,-2.4 -9,-2.3 -2,-0.3 2,-0.4 -0.971 8.8-160.3-140.0 152.5 85.3 114.8 90.9 69 347 A V E -OQ 58 80C 0 11,-1.9 11,-2.6 -2,-0.3 2,-0.6 -0.998 5.4-156.6-136.3 132.1 82.1 113.1 90.1 70 348 A L E +OQ 57 79C 0 -13,-2.4 -14,-1.8 -2,-0.4 -13,-1.7 -0.950 31.3 165.2-108.3 119.8 81.7 110.3 87.6 71 349 A A E -OQ 55 78C 1 7,-4.1 7,-4.5 -2,-0.6 2,-0.5 -0.844 39.8-119.4-136.4 173.3 78.1 110.1 86.4 72 350 A L E +OQ 54 77C 0 -18,-3.1 -18,-3.0 -2,-0.3 2,-0.4 -0.939 35.2 162.5-112.2 122.6 75.7 108.8 83.8 73 351 A R E > S+ Q 0 76C 56 3,-2.8 3,-1.2 -2,-0.5 -20,-0.2 -0.951 72.9 1.0-144.8 122.4 73.7 111.3 81.8 74 352 A A T 3 S- 0 0 80 -2,-0.4 -21,-0.2 1,-0.3 3,-0.1 0.758 129.5 -64.5 71.7 25.1 71.9 110.5 78.6 75 353 A G T 3 S+ 0 0 0 -23,-3.5 21,-2.8 1,-0.3 22,-0.9 0.528 119.0 102.0 76.2 4.6 73.2 106.9 79.1 76 354 A R E < S-Q 73 0C 97 -3,-1.2 -3,-2.8 -24,-0.4 2,-0.3 -0.772 81.3 -89.7-118.9 163.9 76.7 108.1 78.7 77 355 A L E -QR 72 92C 0 15,-0.9 15,-1.3 17,-0.5 2,-0.4 -0.557 39.5-171.4 -76.6 130.7 79.6 108.8 81.1 78 356 A E E -QR 71 91C 12 -7,-4.5 -7,-4.1 -2,-0.3 2,-0.5 -0.959 5.3-162.8-121.1 139.6 79.8 112.3 82.5 79 357 A L E -QR 70 90C 0 11,-3.1 11,-2.4 -2,-0.4 2,-0.4 -0.971 3.1-167.2-125.2 120.0 82.7 113.7 84.5 80 358 A Q E -QR 69 89C 1 -11,-2.6 -11,-1.9 -2,-0.5 2,-0.4 -0.883 7.7-169.1-107.7 137.0 82.5 116.8 86.6 81 359 A L E +Q 68 0C 1 7,-2.7 7,-0.4 -2,-0.4 2,-0.4 -0.969 16.6 176.5-127.9 139.4 85.5 118.5 88.1 82 360 A R E +Q 67 0C 41 -15,-2.2 -15,-2.3 -2,-0.4 2,-0.4 -0.957 2.4 174.5-138.9 114.2 86.0 121.2 90.6 83 361 A Y E S-Q 66 0C 26 3,-1.1 3,-0.3 -2,-0.4 -17,-0.3 -0.661 82.1 -35.5-119.6 69.4 89.6 122.0 91.4 84 362 A N S S- 0 0 101 -19,-2.6 2,-1.8 -2,-0.4 -1,-0.2 0.974 122.0 -34.8 75.5 85.0 88.9 125.0 93.7 85 363 A G S S+ 0 0 58 -20,-0.4 2,-1.1 -21,-0.2 -1,-0.2 -0.038 108.1 115.3 70.4 -37.8 86.0 127.0 92.3 86 364 A V - 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