==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TNF SIGNALING 23-FEB-99 1CA4 . COMPND 2 MOLECULE: PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2); . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR Y.C.PARK,V.BURKITT,A.R.VILLA,L.TONG,H.WU . 1008 6 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 45596.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 643 63.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 265 26.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 6 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 83 8.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 106 10.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 129 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 12 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 6 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 9 11 1 0 18 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 3 3 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 334 A A > 0 0 116 0, 0.0 4,-2.5 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 -67.3 32.1 53.9 32.0 2 335 A M H > + 0 0 81 1,-0.2 4,-2.1 2,-0.2 5,-0.2 0.948 360.0 41.8 -54.5 -51.2 30.2 51.6 29.7 3 336 A A H > S+ 0 0 81 1,-0.2 4,-1.9 2,-0.2 -1,-0.2 0.886 114.7 51.3 -63.6 -40.8 30.3 48.8 32.3 4 337 A D H > S+ 0 0 64 1,-0.2 4,-1.7 2,-0.2 -1,-0.2 0.791 110.1 50.4 -67.8 -28.2 29.5 51.3 35.1 5 338 A L H X S+ 0 0 30 -4,-2.5 4,-2.1 2,-0.2 -2,-0.2 0.877 106.9 53.1 -76.4 -39.1 26.5 52.6 33.1 6 339 A E H X S+ 0 0 32 -4,-2.1 4,-2.5 -5,-0.2 -2,-0.2 0.897 107.5 54.1 -61.0 -39.9 25.2 49.0 32.6 7 340 A Q H X S+ 0 0 55 -4,-1.9 4,-2.7 1,-0.2 5,-0.3 0.954 106.6 48.8 -59.1 -53.2 25.5 48.6 36.4 8 341 A K H X S+ 0 0 34 -4,-1.7 4,-2.6 1,-0.2 -1,-0.2 0.893 111.7 52.2 -54.5 -40.1 23.4 51.7 37.1 9 342 A V H X S+ 0 0 2 -4,-2.1 4,-2.5 2,-0.2 -1,-0.2 0.925 110.1 46.0 -62.8 -47.9 20.8 50.3 34.5 10 343 A L H X S+ 0 0 98 -4,-2.5 4,-1.5 2,-0.2 -2,-0.2 0.899 113.2 49.9 -62.5 -41.9 20.6 46.9 36.2 11 344 A E H X S+ 0 0 47 -4,-2.7 4,-2.0 2,-0.2 3,-0.4 0.935 112.3 47.5 -63.0 -45.6 20.3 48.4 39.6 12 345 A M H < S+ 0 0 33 -4,-2.6 -2,-0.2 -5,-0.3 -1,-0.2 0.903 110.1 54.5 -60.8 -40.9 17.5 50.7 38.4 13 346 A E H < S+ 0 0 100 -4,-2.5 -1,-0.2 1,-0.2 -2,-0.2 0.768 114.1 39.0 -64.9 -29.6 15.8 47.8 36.7 14 347 A A H < S+ 0 0 25 -4,-1.5 -1,-0.2 -3,-0.4 -2,-0.2 0.718 91.4 109.3 -95.1 -22.2 15.7 45.7 39.9 15 348 A S < - 0 0 13 -4,-2.0 2,-0.3 -5,-0.2 33,-0.2 -0.148 43.5-172.7 -59.8 146.9 14.8 48.5 42.4 16 349 A T - 0 0 3 31,-0.2 33,-2.8 35,-0.1 3,-0.1 -0.918 15.7-153.7-133.4 157.4 11.4 48.7 44.1 17 350 A Y S S+ 0 0 72 -2,-0.3 35,-0.2 31,-0.2 36,-0.1 0.009 76.7 71.8-126.6 31.3 10.1 51.5 46.3 18 351 A D S S- 0 0 84 2,-0.3 32,-0.2 33,-0.2 -1,-0.1 0.144 106.1-101.4-129.7 20.0 7.5 49.9 48.5 19 352 A G S S+ 0 0 0 30,-2.6 144,-3.2 1,-0.2 2,-0.5 0.511 90.9 110.4 75.7 2.7 9.6 47.8 50.9 20 353 A V E +A 162 0A 41 29,-0.2 2,-0.4 142,-0.2 -2,-0.3 -0.959 42.0 175.0-115.3 124.9 8.8 44.6 49.1 21 354 A F E -A 161 0A 3 140,-2.5 140,-2.8 -2,-0.5 2,-0.5 -0.987 16.5-164.4-132.2 136.8 11.6 42.9 47.1 22 355 A I E -A 160 0A 22 -2,-0.4 2,-0.6 138,-0.2 138,-0.2 -0.985 9.2-164.0-123.3 122.9 11.7 39.6 45.3 23 356 A W E -A 159 0A 24 136,-3.6 136,-2.7 -2,-0.5 2,-0.5 -0.910 2.1-161.0-112.8 107.8 15.2 38.3 44.4 24 357 A K E -A 158 0A 84 -2,-0.6 2,-0.7 134,-0.2 134,-0.2 -0.761 4.1-161.1 -87.9 125.7 15.3 35.6 41.8 25 358 A I E -A 157 0A 4 132,-3.2 132,-1.6 -2,-0.5 3,-0.3 -0.872 13.0-175.7-112.6 99.8 18.6 33.7 41.9 26 359 A S E +A 156 0A 44 -2,-0.7 130,-0.2 130,-0.2 5,-0.1 -0.331 64.7 41.4 -84.2 172.1 19.1 31.8 38.6 27 360 A D S > S+ 0 0 73 128,-0.5 4,-2.3 127,-0.2 5,-0.3 0.895 72.7 163.7 54.1 40.6 22.0 29.4 37.9 28 361 A F H > + 0 0 8 127,-2.1 4,-2.7 -3,-0.3 5,-0.2 0.890 63.9 53.4 -56.2 -47.9 21.4 28.1 41.4 29 362 A A H > S+ 0 0 52 2,-0.2 4,-2.1 1,-0.2 -1,-0.2 0.950 112.4 43.6 -54.6 -54.5 23.4 24.9 41.0 30 363 A R H > S+ 0 0 115 1,-0.2 4,-2.4 2,-0.2 5,-0.2 0.946 116.6 45.3 -56.9 -54.3 26.6 26.7 39.8 31 364 A K H X S+ 0 0 50 -4,-2.3 4,-1.2 1,-0.2 -1,-0.2 0.867 110.6 56.1 -59.4 -35.9 26.4 29.5 42.4 32 365 A R H X S+ 0 0 32 -4,-2.7 4,-2.0 -5,-0.3 -1,-0.2 0.902 110.7 43.6 -63.9 -41.5 25.7 26.9 45.1 33 366 A Q H X S+ 0 0 120 -4,-2.1 4,-2.5 2,-0.2 6,-0.3 0.853 108.1 57.8 -72.4 -35.2 28.9 25.0 44.2 34 367 A E H <>S+ 0 0 22 -4,-2.4 6,-2.9 1,-0.2 5,-1.2 0.762 110.2 46.3 -65.9 -23.1 30.9 28.2 43.9 35 368 A A H ><5S+ 0 0 9 -4,-1.2 3,-1.3 -5,-0.2 -2,-0.2 0.876 109.6 52.0 -83.3 -43.1 29.9 28.8 47.5 36 369 A V H 3<5S+ 0 0 64 -4,-2.0 -2,-0.2 1,-0.3 -3,-0.2 0.874 110.3 49.9 -60.1 -37.2 30.7 25.2 48.6 37 370 A A T 3<5S- 0 0 64 -4,-2.5 -1,-0.3 -5,-0.1 -2,-0.2 0.531 111.9-124.2 -78.8 -6.9 34.1 25.6 47.1 38 371 A G T < 5S+ 0 0 51 -3,-1.3 -3,-0.2 -5,-0.2 -2,-0.1 0.582 81.4 118.0 74.0 8.2 34.5 28.9 48.9 39 372 A R S S- 0 0 54 4,-0.3 3,-2.4 -35,-0.1 -33,-0.2 -0.947 91.3 -77.7-159.8 172.0 9.5 54.6 49.7 52 385 A R T 3 S+ 0 0 64 1,-0.3 -34,-0.1 -2,-0.3 -1,-0.0 0.843 135.2 16.8 -47.4 -40.3 10.5 56.7 46.6 53 386 A Y T 3 S+ 0 0 36 -36,-0.1 -1,-0.3 32,-0.0 35,-0.1 -0.247 110.4 113.1-125.6 43.3 12.9 58.6 48.8 54 387 A G S < S- 0 0 3 -3,-2.4 31,-0.4 1,-0.2 35,-0.1 0.004 72.2 -37.3 -99.7-155.9 13.2 56.2 51.7 55 388 A Y - 0 0 6 28,-0.1 -5,-1.1 29,-0.1 2,-0.5 -0.386 54.9-132.9 -67.1 143.6 15.8 53.9 53.3 56 389 A K E +FG 49 81B 50 25,-0.6 25,-2.7 -7,-0.2 2,-0.3 -0.854 36.6 165.0 -99.9 133.1 18.2 52.1 50.9 57 390 A M E +FG 48 80B 0 -9,-2.5 -9,-2.2 -2,-0.5 2,-0.3 -0.910 17.0 177.3-143.1 165.6 18.6 48.4 51.5 58 391 A C E - G 0 79B 2 21,-1.8 21,-2.5 -2,-0.3 2,-0.3 -0.956 24.2-116.7-159.5 171.4 19.9 45.2 50.0 59 392 A L E - G 0 78B 0 -13,-0.4 -14,-2.5 -2,-0.3 2,-0.4 -0.791 12.2-156.5-116.0 160.2 20.3 41.5 50.9 60 393 A R E -EG 44 77B 82 17,-2.1 17,-2.9 -2,-0.3 2,-0.4 -0.989 15.1-171.2-137.1 127.0 23.4 39.3 51.3 61 394 A I E -EG 43 76B 0 -18,-2.4 -18,-1.8 -2,-0.4 2,-0.6 -0.919 18.3-158.2-125.1 145.0 23.1 35.5 51.0 62 395 A Y E > - G 0 75B 30 13,-2.6 13,-2.0 -2,-0.4 3,-1.6 -0.954 7.3-161.6-119.3 107.4 25.5 32.6 51.6 63 396 A L T 3 S+ 0 0 4 -2,-0.6 -1,-0.1 -22,-0.4 -21,-0.1 0.659 95.1 33.4 -64.7 -15.1 24.4 29.6 49.6 64 397 A N T 3 S- 0 0 35 -23,-0.5 7,-3.6 1,-0.2 -1,-0.3 0.086 121.9 -99.5-125.8 20.5 26.5 27.3 51.8 65 398 A G < - 0 0 13 -3,-1.6 2,-0.3 5,-0.3 5,-0.3 0.151 24.5-132.6 88.2 161.5 26.2 29.2 55.1 66 399 A D > - 0 0 64 71,-0.5 3,-2.2 4,-0.1 4,-0.1 -0.974 67.9 -11.5-150.7 149.6 27.9 31.7 57.4 67 400 A G G > S- 0 0 54 -2,-0.3 3,-1.9 1,-0.3 8,-0.0 -0.267 136.4 -0.3 57.5-136.5 28.5 31.7 61.1 68 401 A T G 3 S+ 0 0 111 1,-0.3 -1,-0.3 3,-0.0 70,-0.0 0.597 140.4 51.4 -60.9 -9.3 26.5 29.0 62.9 69 402 A G G X> S+ 0 0 0 -3,-2.2 4,-3.2 3,-0.1 3,-2.3 0.485 76.2 134.4-106.3 -4.2 25.0 28.0 59.6 70 403 A R T <4 S+ 0 0 56 -3,-1.9 -5,-0.3 1,-0.3 -4,-0.1 -0.152 81.1 0.5 -49.6 132.3 28.3 27.6 57.6 71 404 A G T 34 S+ 0 0 45 -7,-3.6 -1,-0.3 2,-0.2 -6,-0.2 0.361 134.6 54.8 70.2 -5.8 28.4 24.4 55.6 72 405 A T T <4 S+ 0 0 72 -3,-2.3 70,-3.1 1,-0.2 71,-0.4 0.617 103.9 32.9-128.7 -26.7 24.9 23.4 56.7 73 406 A H E < S- H 0 141B 40 -4,-3.2 2,-0.6 68,-0.3 -2,-0.2 -0.851 72.8-108.9-132.4 169.1 22.4 26.1 56.0 74 407 A L E - H 0 140B 0 66,-3.4 66,-1.7 -2,-0.3 2,-0.5 -0.856 39.8-153.3 -92.1 125.9 21.6 28.9 53.6 75 408 A S E -G 62 0B 0 -13,-2.0 -13,-2.6 -2,-0.6 2,-0.4 -0.918 11.6-170.5-107.2 129.8 22.3 32.1 55.5 76 409 A L E -GH 61 136B 0 60,-2.0 60,-3.6 -2,-0.5 2,-0.3 -0.973 3.7-174.3-124.2 131.4 20.4 35.3 54.6 77 410 A F E -GH 60 135B 20 -17,-2.9 -17,-2.1 -2,-0.4 2,-0.4 -0.909 19.4-135.6-127.8 155.0 21.1 38.8 55.9 78 411 A F E -GH 59 134B 3 56,-3.3 56,-1.8 -2,-0.3 2,-0.4 -0.820 21.0-161.3-102.7 140.7 19.5 42.2 55.6 79 412 A V E -G 58 0B 2 -21,-2.5 -21,-1.8 -2,-0.4 2,-0.6 -0.985 12.3-150.2-131.0 127.6 21.7 45.3 55.0 80 413 A V E -G 57 0B 2 -2,-0.4 51,-2.5 42,-0.4 -23,-0.2 -0.848 26.6-163.9 -92.0 124.0 20.9 48.9 55.6 81 414 A M E -GI 56 130B 8 -25,-2.7 -25,-0.6 -2,-0.6 2,-0.6 -0.646 31.5 -88.5-106.5 163.5 22.9 51.0 53.0 82 415 A K - 0 0 95 47,-2.6 -25,-0.1 -2,-0.2 43,-0.0 -0.606 51.3-156.0 -71.4 118.0 23.8 54.6 52.8 83 416 A G > - 0 0 7 -2,-0.6 3,-1.5 -27,-0.1 4,-0.2 -0.658 24.8-120.1 -97.0 155.2 20.8 56.2 51.0 84 417 A P T 3 S+ 0 0 63 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.702 115.5 39.5 -63.2 -20.0 20.8 59.5 49.0 85 418 A N T > S+ 0 0 11 -31,-0.4 3,-2.3 1,-0.1 4,-0.5 0.101 72.7 123.4-118.5 21.5 18.1 60.8 51.4 86 419 A D G X + 0 0 2 -3,-1.5 3,-1.6 1,-0.3 -1,-0.1 0.825 68.5 66.3 -52.7 -33.7 19.3 59.5 54.7 87 420 A A G 3 S+ 0 0 24 1,-0.3 -1,-0.3 -4,-0.2 -2,-0.1 0.748 102.2 49.3 -61.0 -21.6 19.4 63.0 56.2 88 421 A L G < S+ 0 0 57 -3,-2.3 -1,-0.3 -35,-0.1 2,-0.2 0.513 99.8 85.9 -94.9 -6.3 15.7 63.1 55.8 89 422 A L S < S- 0 0 31 -3,-1.6 2,-0.3 -4,-0.5 4,-0.0 -0.610 81.1-108.5-100.2 156.3 15.1 59.8 57.5 90 423 A R - 0 0 70 -2,-0.2 4,-0.2 2,-0.0 -2,-0.1 -0.595 46.2-116.3 -80.3 139.4 14.7 58.8 61.2 91 424 A W S S+ 0 0 62 -2,-0.3 2,-0.2 2,-0.1 33,-0.1 -0.966 84.2 43.5-131.8 147.7 17.6 56.9 62.7 92 425 A P S S- 0 0 34 0, 0.0 32,-0.2 0, 0.0 2,-0.2 0.548 92.5-113.7 -70.0 162.9 18.2 54.3 63.9 93 426 A F + 0 0 0 30,-2.9 -2,-0.1 -2,-0.2 -13,-0.0 -0.472 42.5 172.1 -63.3 130.1 16.4 52.2 61.3 94 427 A N + 0 0 88 -2,-0.2 2,-0.4 -4,-0.2 -1,-0.1 -0.082 23.3 128.6-138.5 39.8 13.5 50.6 63.2 95 428 A Q - 0 0 18 20,-0.0 70,-0.1 1,-0.0 19,-0.1 -0.807 61.8-111.8-101.0 137.4 11.3 48.8 60.7 96 429 A K - 0 0 70 -2,-0.4 68,-2.5 19,-0.1 2,-0.4 -0.369 33.9-152.2 -61.3 140.5 10.3 45.2 61.1 97 430 A V E -BC 114 163A 0 17,-2.6 17,-2.3 66,-0.2 2,-0.5 -0.978 10.9-167.7-124.5 128.3 11.9 43.0 58.4 98 431 A T E -BC 113 162A 20 64,-2.7 64,-3.0 -2,-0.4 2,-0.4 -0.952 6.7-170.8-114.7 130.4 10.4 39.7 57.0 99 432 A L E -BC 112 161A 1 13,-2.7 13,-2.0 -2,-0.5 2,-0.3 -0.955 7.3-178.2-122.6 140.8 12.6 37.4 54.9 100 433 A M E -BC 111 160A 20 60,-2.6 60,-2.6 -2,-0.4 2,-0.6 -0.984 29.7-147.6-142.8 150.2 11.4 34.4 53.0 101 434 A L E -BC 110 159A 0 9,-2.1 9,-2.4 -2,-0.3 2,-0.3 -0.981 41.2-128.9-110.5 115.8 12.5 31.6 50.8 102 435 A L - 0 0 16 56,-2.7 2,-0.6 -2,-0.6 56,-0.4 -0.527 4.9-138.2 -79.5 132.4 9.6 31.0 48.4 103 436 A D > - 0 0 9 -2,-0.3 3,-2.4 1,-0.1 48,-0.2 -0.753 9.6-150.2 -82.2 116.2 8.1 27.5 47.9 104 437 A Q T 3 S+ 0 0 20 46,-2.4 -1,-0.1 -2,-0.6 47,-0.1 0.191 101.8 52.8 -78.0 21.2 7.4 27.3 44.2 105 438 A N T 3 S- 0 0 85 321,-0.0 -1,-0.3 3,-0.0 46,-0.1 0.041 105.9-135.7-131.2 8.0 4.6 25.0 45.0 106 439 A N S < S+ 0 0 124 -3,-2.4 3,-0.1 44,-0.2 -2,-0.1 0.703 74.0 114.9 36.5 33.1 3.3 27.7 47.4 107 440 A R S S+ 0 0 86 1,-0.2 2,-0.2 43,-0.0 -1,-0.2 0.845 84.7 1.8 -93.9 -40.6 2.7 24.9 50.0 108 441 A E - 0 0 52 2,-0.0 -1,-0.2 42,-0.0 2,-0.2 -0.705 67.2-165.9-154.8 97.8 5.3 25.9 52.7 109 442 A H - 0 0 63 -2,-0.2 2,-0.5 -3,-0.1 -7,-0.2 -0.498 27.0-118.9 -81.4 150.5 7.5 29.0 52.5 110 443 A V E +B 101 0A 16 -9,-2.4 -9,-2.1 -2,-0.2 2,-0.4 -0.793 43.7 178.7 -87.6 130.5 10.5 29.4 54.8 111 444 A I E +B 100 0A 105 -2,-0.5 2,-0.3 -11,-0.2 -11,-0.2 -0.996 19.6 162.3-141.8 142.6 9.9 32.5 56.8 112 445 A D E -B 99 0A 75 -13,-2.0 -13,-2.7 -2,-0.4 2,-0.3 -0.966 11.5-172.5-148.4 155.0 11.6 34.5 59.6 113 446 A A E -B 98 0A 40 -2,-0.3 2,-0.3 -15,-0.2 -15,-0.2 -0.990 1.5-174.8-153.5 145.8 11.1 38.1 60.8 114 447 A F E -B 97 0A 44 -17,-2.3 -17,-2.6 -2,-0.3 -2,-0.0 -0.985 24.3-131.7-145.4 154.2 12.9 40.4 63.2 115 448 A R - 0 0 169 -2,-0.3 -19,-0.1 -19,-0.2 3,-0.0 -0.933 46.1-103.4-105.9 120.6 12.6 43.8 64.8 116 449 A P - 0 0 10 0, 0.0 2,-1.2 0, 0.0 -20,-0.0 -0.058 23.4-122.5 -44.8 135.5 15.8 45.7 64.5 117 450 A D > - 0 0 91 1,-0.2 3,-2.7 2,-0.0 6,-0.3 -0.746 22.5-153.8 -82.3 99.4 17.9 46.0 67.7 118 451 A V T 3 S+ 0 0 62 -2,-1.2 -1,-0.2 1,-0.3 5,-0.1 0.682 90.1 57.9 -49.7 -21.2 18.0 49.8 67.9 119 452 A T T 3 S+ 0 0 121 -27,-0.0 -1,-0.3 -3,-0.0 2,-0.1 0.601 85.7 100.1 -88.9 -11.0 21.3 49.6 69.8 120 453 A S S X S- 0 0 33 -3,-2.7 3,-1.4 1,-0.1 4,-0.1 -0.464 75.9-132.2 -76.7 147.5 23.1 47.7 67.1 121 454 A S G > S+ 0 0 68 1,-0.3 3,-1.1 2,-0.2 11,-0.2 0.673 100.3 78.8 -70.7 -17.0 25.5 49.5 64.7 122 455 A S G 3 S+ 0 0 8 1,-0.2 -42,-0.4 9,-0.2 -1,-0.3 0.712 100.5 37.9 -64.0 -19.6 23.7 47.6 61.9 123 456 A F G < S+ 0 0 7 -3,-1.4 -30,-2.9 -6,-0.3 -1,-0.2 0.267 90.1 107.6-119.0 15.1 20.8 50.1 62.1 124 457 A Q S < S- 0 0 74 -3,-1.1 3,-0.1 -32,-0.2 7,-0.0 -0.391 90.0 -70.4 -85.2 167.6 22.5 53.4 62.8 125 458 A R - 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