==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=29-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER CHAPERONE 18-JAN-06 2CCU . COMPND 2 MOLECULE: HEAT SHOCK PROTEIN HSP-90 ALPHA; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR X.BARRIL,M.C.BESWICK,A.COLLIER,M.J.DRYSDALE,B.W.DYMOCK, . 208 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10222.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 157 75.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 38 18.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 22 10.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 30 14.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 59 28.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 1 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A E 0 0 143 0, 0.0 2,-0.6 0, 0.0 158,-0.4 0.000 360.0 360.0 360.0-140.1 37.7 28.9 38.4 2 17 A V - 0 0 73 156,-0.1 156,-0.2 154,-0.0 0, 0.0 -0.805 360.0-155.6-129.2 84.8 39.4 26.9 35.6 3 18 A E E -A 157 0A 92 154,-0.9 154,-2.2 -2,-0.6 2,-0.3 -0.266 15.3-149.6 -65.7 142.9 42.2 24.3 35.6 4 19 A T E -A 156 0A 98 152,-0.2 2,-0.3 150,-0.0 152,-0.2 -0.885 12.2-171.8-112.5 145.6 44.3 23.8 32.4 5 20 A F E -A 155 0A 52 150,-2.2 150,-1.8 -2,-0.3 2,-0.3 -0.930 23.1-119.3-134.0 146.7 46.0 20.6 31.3 6 21 A A E -A 154 0A 84 -2,-0.3 2,-0.4 148,-0.2 148,-0.2 -0.690 28.9-121.5 -79.3 140.6 48.5 19.6 28.6 7 22 A F - 0 0 8 146,-1.1 5,-0.1 -2,-0.3 82,-0.0 -0.719 43.5 -97.5 -72.1 130.8 47.3 17.1 25.9 8 23 A Q >> - 0 0 86 -2,-0.4 3,-2.2 1,-0.1 4,-2.0 -0.270 40.9-101.6 -44.2 131.9 49.7 14.2 26.0 9 24 A A H 3> S+ 0 0 67 1,-0.3 4,-1.5 2,-0.2 -1,-0.1 0.725 122.1 49.4 -11.1 -62.4 52.4 14.6 23.3 10 25 A E H 3> S+ 0 0 70 2,-0.2 4,-1.8 1,-0.2 -1,-0.3 0.740 111.4 47.3 -66.7 -30.4 50.6 12.0 21.0 11 26 A I H <> S+ 0 0 0 -3,-2.2 4,-2.2 2,-0.2 -1,-0.2 0.870 112.9 47.6 -82.9 -39.9 47.2 13.6 21.2 12 27 A A H X S+ 0 0 26 -4,-2.0 4,-1.8 1,-0.2 -2,-0.2 0.873 112.3 55.0 -59.2 -33.7 48.5 17.1 20.6 13 28 A Q H X S+ 0 0 114 -4,-1.5 4,-0.9 -5,-0.4 -2,-0.2 0.902 108.7 45.4 -70.1 -47.3 50.4 15.4 17.7 14 29 A L H >X S+ 0 0 0 -4,-1.8 3,-2.2 2,-0.2 4,-1.7 0.984 107.3 56.2 -55.3 -69.9 47.2 14.0 16.3 15 30 A M H 3X S+ 0 0 3 -4,-2.2 4,-3.0 1,-0.3 5,-0.2 0.773 105.9 51.4 -33.9 -50.7 45.2 17.2 16.5 16 31 A S H 3X S+ 0 0 61 -4,-1.8 4,-1.8 2,-0.2 -1,-0.3 0.774 107.5 53.1 -64.3 -28.7 47.8 19.1 14.5 17 32 A L H + 0 0 64 1,-0.2 3,-1.2 2,-0.1 -1,-0.2 -0.331 49.7 151.6 -82.6 56.9 35.9 15.0 3.2 26 41 A K T > + 0 0 30 -2,-1.8 3,-1.3 1,-0.2 -1,-0.2 0.574 48.6 89.6 -63.0 -11.4 35.5 16.8 6.5 27 42 A E T >> + 0 0 36 1,-0.3 3,-1.1 -3,-0.2 4,-0.6 0.558 64.5 79.2 -68.5 -15.2 31.9 15.6 6.9 28 43 A I H <> + 0 0 1 -3,-1.2 4,-1.8 1,-0.3 3,-0.4 0.730 69.4 84.6 -69.8 -20.1 32.8 12.4 8.7 29 44 A F H <> S+ 0 0 0 -3,-1.3 4,-1.4 1,-0.2 -1,-0.3 0.869 89.5 50.6 -50.9 -36.2 33.2 14.3 11.9 30 45 A L H <> S+ 0 0 3 -3,-1.1 4,-2.0 1,-0.2 -1,-0.2 0.875 105.5 55.1 -74.6 -33.7 29.4 14.0 12.5 31 46 A R H X S+ 0 0 52 -4,-0.6 4,-1.9 -3,-0.4 -1,-0.2 0.856 110.0 50.8 -53.8 -34.6 29.5 10.2 11.9 32 47 A E H X S+ 0 0 11 -4,-1.8 4,-1.1 2,-0.2 -2,-0.2 0.817 110.2 42.3 -84.2 -30.2 32.2 10.2 14.5 33 48 A L H X S+ 0 0 4 -4,-1.4 4,-1.9 2,-0.2 -1,-0.2 0.831 113.5 54.5 -89.2 -33.5 30.5 12.0 17.3 34 49 A I H X S+ 0 0 1 -4,-2.0 4,-3.1 2,-0.2 -2,-0.2 0.935 107.4 50.6 -53.1 -52.3 27.2 10.3 16.6 35 50 A S H X S+ 0 0 50 -4,-1.9 4,-1.8 1,-0.2 -2,-0.2 0.806 108.9 53.3 -62.1 -34.4 29.0 6.9 17.0 36 51 A N H X S+ 0 0 64 -4,-1.1 4,-1.2 2,-0.2 -1,-0.2 0.882 111.3 42.2 -62.2 -51.9 30.5 8.1 20.3 37 52 A S H >X S+ 0 0 5 -4,-1.9 4,-2.6 2,-0.2 3,-1.0 0.952 111.5 57.0 -61.0 -54.1 27.1 9.0 21.8 38 53 A S H 3X S+ 0 0 16 -4,-3.1 4,-1.5 1,-0.3 -2,-0.2 0.881 107.7 49.1 -38.1 -50.1 25.7 5.8 20.4 39 54 A D H 3X S+ 0 0 77 -4,-1.8 4,-0.8 -5,-0.2 -1,-0.3 0.798 110.5 50.5 -57.8 -35.2 28.5 4.1 22.4 40 55 A A H X S+ 0 0 113 -4,-2.4 3,-0.9 2,-0.2 4,-0.6 0.962 111.5 43.2 -64.6 -49.2 21.5 0.7 28.8 46 61 A Y H >X S+ 0 0 166 -4,-2.3 3,-1.4 1,-0.2 4,-0.6 0.916 112.1 56.7 -55.8 -43.2 23.7 -2.2 29.8 47 62 A E H 3X S+ 0 0 60 -4,-1.9 4,-1.0 1,-0.3 -1,-0.2 0.689 105.9 50.0 -62.8 -24.7 24.2 -0.5 33.1 48 63 A T H << S+ 0 0 18 -4,-1.0 -1,-0.3 -3,-0.9 -2,-0.2 0.487 90.0 77.4 -92.8 -7.5 20.4 -0.5 33.7 49 64 A L H << S+ 0 0 132 -3,-1.4 -2,-0.2 -4,-0.6 -1,-0.2 0.834 111.7 25.8 -71.9 -25.8 19.9 -4.2 32.8 50 65 A T H < S+ 0 0 114 -4,-0.6 -2,-0.2 1,-0.3 -1,-0.1 0.755 135.6 29.8-105.5 -37.1 21.2 -5.0 36.4 51 66 A D >< - 0 0 57 -4,-1.0 3,-1.0 1,-0.1 -1,-0.3 -0.907 64.9-172.8-124.9 102.9 20.4 -1.8 38.3 52 67 A P T 3 S+ 0 0 103 0, 0.0 3,-0.3 0, 0.0 -4,-0.1 0.484 76.5 71.6 -82.9 0.3 17.3 -0.0 36.9 53 68 A S T 3 S+ 0 0 66 1,-0.2 3,-0.1 2,-0.1 4,-0.1 0.044 75.0 80.4-100.2 22.4 17.6 3.1 39.1 54 69 A K S X S+ 0 0 56 -3,-1.0 3,-1.0 1,-0.1 -1,-0.2 0.734 87.3 60.7 -81.3 -31.7 20.7 4.3 37.1 55 70 A L T 3 S+ 0 0 33 -3,-0.3 3,-0.2 -4,-0.3 -2,-0.1 0.244 73.7 101.6 -81.3 14.8 18.0 5.6 34.7 56 71 A D T 3 + 0 0 129 1,-0.2 2,-1.7 -3,-0.1 -1,-0.3 0.852 68.2 68.3 -63.7 -34.1 16.7 7.8 37.4 57 72 A S S < S- 0 0 27 -3,-1.0 -1,-0.2 1,-0.3 83,-0.0 -0.466 132.4 -34.7 -88.2 65.5 18.4 10.7 35.8 58 73 A G - 0 0 38 -2,-1.7 -1,-0.3 -3,-0.2 -2,-0.1 0.740 62.2-146.5 84.5 109.5 16.3 10.9 32.7 59 74 A K + 0 0 175 -3,-0.2 2,-0.3 2,-0.0 -1,-0.1 0.323 66.1 86.8 -99.1 9.3 15.1 7.6 31.4 60 75 A E - 0 0 116 -5,-0.0 2,-0.5 2,-0.0 0, 0.0 -0.870 61.0-148.4-113.6 150.7 15.0 8.1 27.6 61 76 A L + 0 0 25 -2,-0.3 2,-0.3 17,-0.1 -2,-0.0 -0.946 36.4 120.3-131.5 111.8 17.9 7.6 25.3 62 77 A H - 0 0 31 -2,-0.5 17,-1.0 139,-0.1 2,-0.4 -0.922 50.6-114.3-163.0 168.3 18.5 9.6 22.1 63 78 A I E -Bc 78 203A 0 139,-2.3 141,-2.6 -2,-0.3 2,-0.4 -0.980 25.4-160.9-121.3 131.6 20.8 12.0 20.2 64 79 A N E -Bc 77 204A 19 13,-3.0 13,-1.6 -2,-0.4 2,-0.5 -0.930 6.1-155.6-112.7 140.8 19.8 15.5 19.4 65 80 A L E -Bc 76 205A 0 139,-3.2 141,-3.2 -2,-0.4 11,-0.2 -0.989 14.5-176.9-114.7 120.1 21.4 17.6 16.7 66 81 A I E -B 75 0A 53 9,-2.5 9,-1.3 -2,-0.5 2,-0.3 -0.897 4.8-167.1-120.9 94.3 21.0 21.4 17.4 67 82 A P E -B 74 0A 10 0, 0.0 2,-0.4 0, 0.0 7,-0.2 -0.610 2.0-168.6 -79.6 139.0 22.3 23.8 14.8 68 83 A N E >> -B 73 0A 47 5,-2.9 5,-1.2 -2,-0.3 4,-0.8 -0.773 10.7-174.6-128.7 99.3 22.6 27.4 15.7 69 84 A K T 45S+ 0 0 51 -2,-0.4 3,-0.1 1,-0.2 -1,-0.1 0.795 83.3 60.4 -64.9 -20.4 23.3 29.7 12.7 70 85 A Q T 45S+ 0 0 162 1,-0.2 -1,-0.2 -3,-0.1 -2,-0.0 0.901 115.1 25.5 -73.5 -50.1 23.7 32.6 15.2 71 86 A D T 45S- 0 0 100 -3,-0.5 -1,-0.2 2,-0.1 -2,-0.2 0.292 106.0-119.4 -94.9 7.0 26.6 31.5 17.4 72 87 A R T <5 + 0 0 69 -4,-0.8 103,-2.2 1,-0.2 2,-0.3 0.777 69.0 137.8 54.3 30.0 28.0 29.3 14.7 73 88 A T E < -BD 68 174A 12 -5,-1.2 -5,-2.9 101,-0.2 2,-0.4 -0.777 39.7-169.6-100.9 153.7 27.6 26.3 16.9 74 89 A L E -BD 67 173A 0 99,-1.4 99,-3.9 -2,-0.3 2,-0.4 -0.970 18.1-161.4-126.8 138.7 26.3 22.8 16.1 75 90 A T E -BD 66 172A 16 -9,-1.3 -9,-2.5 -2,-0.4 2,-0.5 -0.997 13.9-161.6-131.4 130.4 25.7 20.8 19.2 76 91 A I E -BD 65 171A 0 95,-1.7 95,-1.5 -2,-0.4 2,-0.3 -0.965 21.6-178.0-118.1 104.0 25.4 17.0 19.5 77 92 A V E +BD 64 170A 23 -13,-1.6 -13,-3.0 -2,-0.5 2,-0.3 -0.786 3.6 177.3-109.9 140.4 23.7 16.2 22.8 78 93 A D E -B 63 0A 6 91,-1.9 91,-0.4 -2,-0.3 -15,-0.2 -0.916 35.6-134.9-141.9 163.4 22.9 12.7 24.2 79 94 A T + 0 0 19 -17,-1.0 89,-0.2 -2,-0.3 -16,-0.1 -0.022 60.8 134.8-108.4 29.1 21.5 11.1 27.3 80 95 A G S S- 0 0 0 -18,-0.2 -39,-0.3 89,-0.1 -40,-0.1 0.200 76.7 -75.6 -66.4-174.4 24.2 8.4 27.5 81 96 A I - 0 0 24 -41,-1.7 59,-0.4 86,-0.1 87,-0.3 0.844 68.9-144.4 -58.3 -33.9 26.1 7.4 30.7 82 97 A G - 0 0 4 85,-0.2 2,-0.4 57,-0.1 57,-0.2 -0.136 13.6 -84.7 89.9 167.8 28.3 10.6 30.8 83 98 A M - 0 0 31 85,-0.2 2,-0.2 62,-0.1 62,-0.2 -0.902 28.4-136.5-112.4 141.5 31.9 11.1 31.8 84 99 A T >> - 0 0 23 -2,-0.4 4,-2.1 54,-0.1 3,-0.5 -0.647 38.6-100.8 -81.4 159.0 33.3 11.6 35.3 85 100 A K H 3> S+ 0 0 52 1,-0.3 4,-2.0 -2,-0.2 5,-0.2 0.904 126.4 57.7 -38.5 -55.0 36.0 14.3 35.7 86 101 A A H 3> S+ 0 0 60 1,-0.2 4,-1.2 2,-0.2 -1,-0.3 0.914 108.5 46.8 -44.1 -52.7 38.6 11.6 35.7 87 102 A D H X4>S+ 0 0 59 -3,-0.5 6,-1.4 1,-0.2 3,-1.3 0.937 105.1 56.7 -56.1 -54.7 37.3 10.4 32.3 88 103 A L H 3X5S+ 0 0 0 -4,-2.1 4,-1.5 1,-0.3 3,-0.4 0.884 107.7 49.9 -47.0 -49.9 37.2 13.8 30.7 89 104 A I H 3<5S+ 0 0 48 -4,-2.0 2,-1.1 1,-0.3 -1,-0.3 0.766 97.8 70.4 -59.8 -32.8 41.0 14.2 31.5 90 105 A N T + 0 0 101 25,-0.4 3,-1.0 24,-0.2 2,-0.8 0.543 50.3 159.9 -87.8 -15.1 42.9 5.0 24.5 96 111 A A T 3> + 0 0 0 24,-0.4 4,-3.2 1,-0.2 5,-0.2 0.025 64.7 41.2 33.1 -69.9 44.5 8.0 22.6 97 112 A K H 3> S+ 0 0 84 -2,-0.8 4,-2.4 2,-0.2 -1,-0.2 0.998 124.8 40.5 -59.3 -68.4 48.4 7.4 23.0 98 113 A S H <> S+ 0 0 55 -3,-1.0 4,-1.5 1,-0.2 -2,-0.2 0.909 122.8 43.1 -31.9 -63.9 47.8 3.6 22.4 99 114 A G H > S+ 0 0 4 -4,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.870 110.9 51.6 -59.9 -46.9 45.2 4.6 19.7 100 115 A T H X S+ 0 0 2 -4,-3.2 4,-2.8 2,-0.2 -1,-0.2 0.853 104.9 57.9 -63.5 -40.2 47.1 7.4 17.9 101 116 A K H X S+ 0 0 123 -4,-2.4 4,-1.8 -5,-0.2 5,-0.3 0.984 108.5 44.5 -49.8 -62.1 50.1 5.2 17.5 102 117 A A H X S+ 0 0 40 -4,-1.5 4,-2.0 1,-0.2 -1,-0.2 0.881 112.1 56.9 -50.0 -40.7 48.1 2.6 15.5 103 118 A F H X S+ 0 0 2 -4,-1.9 4,-2.2 1,-0.2 -1,-0.2 0.959 106.7 44.6 -60.7 -50.8 46.6 5.4 13.6 104 119 A M H X S+ 0 0 58 -4,-2.8 4,-2.7 2,-0.3 5,-0.2 0.786 110.7 52.1 -74.2 -25.2 49.8 7.0 12.3 105 120 A E H X S+ 0 0 125 -4,-1.8 4,-0.5 2,-0.2 -1,-0.2 0.849 117.1 42.2 -68.9 -39.5 51.4 3.7 11.3 106 121 A A H < S+ 0 0 29 -4,-2.0 -2,-0.3 -5,-0.3 -1,-0.2 0.751 116.8 51.6 -71.0 -28.5 48.2 3.1 9.4 107 122 A L H X S+ 0 0 53 -4,-2.2 4,-0.8 -5,-0.2 3,-0.3 0.997 110.2 41.3 -72.6 -66.2 48.3 6.8 8.3 108 123 A Q H < S+ 0 0 96 -4,-2.7 2,-0.4 1,-0.2 -1,-0.2 0.676 113.5 63.8 -55.5 -18.2 51.8 7.2 6.8 109 124 A A T < S- 0 0 73 -4,-0.5 -1,-0.2 -5,-0.2 -2,-0.1 -0.580 125.7 -62.9-112.4 64.3 51.2 3.7 5.2 110 125 A G T 4 S+ 0 0 81 -2,-0.4 2,-0.2 -3,-0.3 -2,-0.1 0.924 96.5 96.9 64.9 61.3 48.3 3.9 2.7 111 126 A A < - 0 0 35 -4,-0.8 -2,-0.1 0, 0.0 -1,-0.1 -0.781 58.9-125.1-177.5 128.5 44.9 4.9 4.5 112 127 A D > - 0 0 72 -2,-0.2 3,-1.5 1,-0.1 -89,-0.0 -0.031 33.0 -95.1 -84.0 174.5 43.1 8.2 5.0 113 128 A I G > S+ 0 0 6 1,-0.3 3,-1.7 2,-0.1 -1,-0.1 0.693 108.8 81.6 -63.7 -18.8 41.7 10.2 8.0 114 129 A S G 3 S+ 0 0 36 1,-0.3 3,-0.5 2,-0.1 -1,-0.3 0.680 82.3 63.2 -60.6 -22.4 38.2 8.6 7.6 115 130 A M G X + 0 0 49 -3,-1.5 3,-1.5 1,-0.2 -1,-0.3 0.256 69.5 112.1 -84.8 13.2 39.3 5.5 9.4 116 131 A I G X > + 0 0 0 -3,-1.7 5,-1.2 1,-0.3 3,-1.0 0.779 68.9 57.4 -61.7 -31.9 39.9 7.5 12.6 117 132 A G G > 5S+ 0 0 34 -3,-0.5 3,-0.9 1,-0.2 -1,-0.3 0.650 92.3 71.8 -70.8 -16.3 37.1 5.9 14.6 118 133 A Q G < 5S+ 0 0 148 -3,-1.5 -1,-0.2 1,-0.2 -2,-0.2 0.461 98.5 48.8 -72.7 -6.6 38.7 2.4 14.0 119 134 A F G < 5S- 0 0 44 -3,-1.0 -1,-0.2 -4,-0.2 -2,-0.2 0.335 120.7-105.1-116.5 0.4 41.5 3.4 16.4 120 135 A G T < 5S+ 0 0 35 -3,-0.9 -25,-0.4 -4,-0.1 -24,-0.4 0.645 97.5 96.3 82.3 20.2 39.2 4.6 19.2 121 136 A V > < + 0 0 0 -5,-1.2 3,-1.2 -22,-0.1 4,-0.3 0.108 30.2 128.6-130.4 25.0 39.8 8.4 18.6 122 137 A G G > + 0 0 2 1,-0.2 3,-2.0 -5,-0.2 4,-0.3 0.747 59.5 79.7 -45.6 -31.6 37.0 9.6 16.4 123 138 A F G > S+ 0 0 5 1,-0.3 3,-2.0 2,-0.2 -1,-0.2 0.864 84.5 59.5 -48.1 -46.1 36.2 12.5 18.8 124 139 A Y G X S+ 0 0 1 -3,-1.2 3,-1.9 1,-0.3 -1,-0.3 0.581 81.5 80.5 -65.4 -14.2 39.1 14.6 17.5 125 140 A S G X> S+ 0 0 0 -3,-2.0 3,-2.4 1,-0.3 4,-0.5 0.689 73.5 84.1 -66.4 -17.7 37.7 14.7 14.0 126 141 A A H X> S+ 0 0 0 -3,-2.0 4,-2.5 -4,-0.3 3,-1.4 0.898 81.1 60.2 -42.6 -45.1 35.6 17.4 15.6 127 142 A Y H <4 S+ 0 0 1 -3,-1.9 -1,-0.3 1,-0.3 -2,-0.2 0.543 80.8 81.1 -74.9 -1.9 38.5 19.7 14.8 128 143 A L H <4 S+ 0 0 1 -3,-2.4 -1,-0.3 1,-0.1 -2,-0.2 0.935 120.6 7.4 -56.8 -42.4 38.1 19.0 11.0 129 144 A V H << S+ 0 0 0 -3,-1.4 47,-2.7 -4,-0.5 2,-0.4 0.649 116.3 81.8-112.4 -26.1 35.4 21.6 11.3 130 145 A A E < -E 175 0A 1 -4,-2.5 45,-0.3 45,-0.3 3,-0.2 -0.693 45.5-169.3 -96.9 136.4 35.4 23.2 14.8 131 146 A E E S+ 0 0 100 43,-2.4 2,-0.3 -2,-0.4 44,-0.2 0.705 87.2 17.8 -88.9 -22.6 37.8 26.0 15.9 132 147 A K E S-E 174 0A 70 42,-1.2 42,-2.5 18,-0.0 2,-0.5 -0.964 71.8-158.9-144.0 126.8 36.7 25.5 19.6 133 148 A V E -EF 173 149A 0 16,-2.8 16,-2.1 -2,-0.3 2,-0.5 -0.959 3.5-168.2-109.4 126.4 35.0 22.4 21.2 134 149 A T E -EF 172 148A 12 38,-1.6 38,-3.6 -2,-0.5 2,-0.5 -0.931 7.2-161.7-104.4 133.2 33.1 22.6 24.4 135 150 A V E -EF 171 147A 1 12,-3.5 12,-2.8 -2,-0.5 2,-0.5 -0.960 4.3-169.0-121.9 115.3 32.1 19.4 26.0 136 151 A I E +EF 170 146A 9 34,-3.4 34,-3.5 -2,-0.5 2,-0.4 -0.903 14.9 167.8-101.8 130.6 29.4 19.2 28.6 137 152 A T E -EF 169 145A 0 8,-1.5 8,-2.1 -2,-0.5 2,-0.4 -0.997 17.9-178.5-141.0 134.8 28.9 16.0 30.6 138 153 A K E -E 168 0A 39 30,-1.9 30,-2.3 -2,-0.4 2,-0.3 -0.995 8.5-175.6-126.9 139.3 27.1 14.8 33.7 139 154 A H - 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