==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HAEMATOPOIETIC CYTOKINE 25-MAY-99 1CN4 . COMPND 2 MOLECULE: PROTEIN (ERYTHROPOIETIN RECEPTOR); . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR R.M.STROUD,S.W.REID . 589 4 6 5 1 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 29239.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 370 62.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 9 1.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 133 22.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 53 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 49 8.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 106 18.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 0 0 1 0 1 1 1 0 0 0 0 1 0 0 0 0 0 1 0 0 1 0 0 0 RESIDUES PER ALPHA HELIX . 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 8 3 7 5 1 3 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 4 4 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 7 A P 0 0 104 0, 0.0 3,-0.0 0, 0.0 65,-0.0 0.000 360.0 360.0 360.0 -75.5 35.0 62.2 35.6 2 8 A D >> - 0 0 69 1,-0.1 4,-1.8 4,-0.0 3,-1.5 -0.705 360.0-125.0 -94.9 143.9 35.4 59.5 38.3 3 9 A P H 3>>S+ 0 0 95 0, 0.0 4,-2.7 0, 0.0 5,-0.5 0.901 108.8 68.7 -52.5 -42.2 35.5 55.8 37.6 4 10 A K H 3>5S+ 0 0 49 1,-0.2 4,-0.5 2,-0.2 5,-0.0 0.823 106.7 39.2 -44.8 -39.6 32.6 55.3 40.0 5 11 A F H <>5S+ 0 0 12 -3,-1.5 4,-2.5 2,-0.2 5,-0.2 0.945 116.5 47.1 -79.8 -53.1 30.4 57.2 37.5 6 12 A E H >X5S+ 0 0 66 -4,-1.8 4,-1.2 1,-0.3 3,-0.8 0.974 117.1 43.7 -51.0 -61.1 31.7 55.7 34.2 7 13 A S H 3X5S+ 0 0 68 -4,-2.7 4,-0.8 1,-0.3 -1,-0.3 0.751 116.8 47.5 -57.6 -26.0 31.6 52.2 35.5 8 14 A K H 3X< S+ 0 0 26 -4,-1.4 2,-1.5 1,-0.3 3,-0.9 0.860 93.9 61.3 -51.4 -34.9 24.0 52.1 28.9 14 20 A A T 3< S+ 0 0 87 -4,-1.3 -1,-0.3 1,-0.2 -4,-0.0 -0.523 92.7 67.7 -90.5 64.6 22.8 48.5 28.4 15 21 A R T 3 S- 0 0 175 -2,-1.5 -1,-0.2 -3,-0.2 -2,-0.1 0.178 127.6 -43.1-164.5 11.1 19.2 49.5 29.3 16 22 A G X - 0 0 29 -3,-0.9 3,-0.7 5,-0.0 -2,-0.1 0.732 54.2-169.3 114.6 73.7 18.2 51.7 26.3 17 23 A P T 3 S+ 0 0 70 0, 0.0 2,-1.4 0, 0.0 18,-0.3 0.892 84.1 62.5 -55.0 -51.1 20.9 54.3 25.2 18 24 A E T 3 S+ 0 0 108 16,-0.1 2,-0.3 2,-0.1 16,-0.1 0.011 100.4 72.2 -71.7 34.9 18.6 56.3 22.8 19 25 A E S < S- 0 0 101 -2,-1.4 2,-0.6 -3,-0.7 14,-0.1 -0.952 99.0 -92.9-142.1 156.3 16.6 57.1 25.9 20 26 A L - 0 0 4 -2,-0.3 2,-0.7 84,-0.1 14,-0.2 -0.641 37.3-159.6 -79.8 120.7 17.4 59.4 28.8 21 27 A L E +A 33 0A 12 12,-2.3 12,-1.6 -2,-0.6 2,-0.3 -0.862 18.3 167.5-105.4 102.7 19.0 57.5 31.6 22 28 A a E +A 32 0A 2 -2,-0.7 2,-0.3 10,-0.3 10,-0.2 -0.704 1.9 164.3-105.9 163.2 18.8 59.2 35.0 23 29 A F E -A 31 0A 0 8,-1.4 8,-1.4 -2,-0.3 2,-0.4 -0.921 26.6-137.6-173.2 150.5 19.6 57.7 38.4 24 30 A T B -d 113 0B 0 88,-2.2 90,-1.1 -2,-0.3 3,-0.3 -0.981 2.5-162.3-122.0 128.6 20.3 58.8 41.9 25 31 A E S S+ 0 0 34 -2,-0.4 91,-0.5 1,-0.2 -1,-0.1 0.755 90.4 7.5 -79.4 -25.8 23.1 57.3 44.1 26 32 A R S S- 0 0 68 89,-0.1 -1,-0.2 3,-0.1 2,-0.1 -0.223 97.3-104.9-153.4 52.1 21.8 58.5 47.5 27 33 A L S S+ 0 0 3 -3,-0.3 59,-0.2 1,-0.2 82,-0.1 0.490 109.6 84.5 35.1 8.9 18.4 60.1 47.1 28 34 A E S S+ 0 0 55 -2,-0.1 2,-0.3 57,-0.1 -1,-0.2 -0.002 93.0 29.7-121.3 25.3 20.1 63.5 47.5 29 35 A D - 0 0 41 55,-0.2 2,-0.3 80,-0.1 -3,-0.1 -0.965 59.2-156.3-166.8 175.5 21.2 63.9 43.9 30 36 A L - 0 0 4 49,-0.3 49,-2.4 -2,-0.3 2,-0.4 -0.904 6.0-177.5-169.1 138.9 20.4 63.2 40.3 31 37 A V E -AB 23 78A 16 -8,-1.4 -8,-1.4 -2,-0.3 2,-0.4 -0.999 5.2-166.8-141.2 138.9 22.1 62.9 37.0 32 38 A a E +AB 22 77A 0 45,-1.1 45,-1.6 -2,-0.4 2,-0.3 -0.979 18.1 159.4-126.3 142.5 20.8 62.2 33.5 33 39 A F E -AB 21 76A 1 -12,-1.6 -12,-2.3 -2,-0.4 2,-0.3 -0.924 18.5-168.8-150.8 175.4 22.9 61.3 30.5 34 40 A W E - B 0 75A 1 41,-1.2 41,-1.5 -2,-0.3 2,-0.3 -0.912 18.0-132.1-168.8 143.6 22.8 59.7 27.1 35 41 A E E + B 0 74A 37 -2,-0.3 2,-0.2 -18,-0.3 39,-0.2 -0.700 28.8 154.1-105.7 156.7 25.5 58.6 24.7 36 42 A E E - B 0 73A 26 37,-1.3 37,-1.6 -2,-0.3 2,-0.2 -0.697 33.0-136.7-179.0 121.4 25.9 59.1 21.0 37 43 A A + 0 0 72 35,-0.3 2,-0.2 -2,-0.2 35,-0.2 -0.606 41.2 167.1 -80.8 149.5 29.0 59.1 18.8 38 44 A A - 0 0 62 -2,-0.2 2,-0.1 1,-0.1 -1,-0.0 -0.725 32.1 -70.9-146.6-164.3 28.9 62.0 16.4 39 45 A S - 0 0 86 -2,-0.2 3,-0.3 1,-0.1 -1,-0.1 -0.365 58.0 -91.5 -90.9 172.8 30.6 64.3 13.9 40 46 A A S S+ 0 0 111 1,-0.2 -1,-0.1 -2,-0.1 -2,-0.0 0.734 121.1 78.0 -57.8 -17.7 33.2 67.0 14.5 41 47 A G + 0 0 43 2,-0.1 -1,-0.2 5,-0.0 -3,-0.0 0.980 67.2 85.8 -54.4 -71.3 29.9 69.0 14.8 42 48 A V + 0 0 43 -3,-0.3 -4,-0.1 1,-0.1 3,-0.1 -0.010 61.3 131.9 -37.2 125.2 28.7 68.0 18.2 43 49 A G - 0 0 7 1,-0.1 3,-0.3 0, 0.0 4,-0.2 -0.788 64.9 -45.8-156.5-160.8 30.3 70.4 20.8 44 50 A P S > S+ 0 0 120 0, 0.0 2,-1.3 0, 0.0 3,-0.6 0.941 125.8 33.7 -45.1 -81.0 29.7 72.7 23.8 45 51 A G T 3 S+ 0 0 61 1,-0.2 3,-0.1 -3,-0.1 51,-0.0 -0.638 87.4 96.1 -84.9 90.8 26.7 74.6 22.6 46 52 A Q T 3 S+ 0 0 80 -2,-1.3 51,-1.4 1,-0.4 2,-0.3 0.336 81.8 41.3-147.4 -12.0 24.7 72.1 20.5 47 53 A Y E < -F 96 0C 38 -3,-0.6 2,-0.5 49,-0.3 -1,-0.4 -0.997 61.3-154.1-144.5 142.9 22.1 70.8 23.0 48 54 A S E -F 95 0C 56 47,-4.1 47,-0.8 -2,-0.3 2,-0.5 -0.965 9.0-157.2-123.7 119.5 20.0 72.4 25.8 49 55 A F E +FG 94 61C 1 12,-0.6 12,-2.3 -2,-0.5 2,-0.4 -0.804 14.5 179.3 -98.8 130.3 18.8 70.4 28.8 50 56 A S E -FG 93 60C 10 43,-3.6 43,-4.0 -2,-0.5 2,-0.3 -0.994 3.1-179.7-134.4 136.1 15.7 71.6 30.7 51 57 A Y E -FG 92 59C 11 8,-2.6 8,-2.8 -2,-0.4 2,-0.3 -0.819 7.8-164.6-128.2 166.8 13.9 70.2 33.8 52 58 A Q E -F 91 0C 36 39,-1.5 39,-2.2 -2,-0.3 2,-0.4 -0.870 11.9-146.0-159.9 123.1 10.9 71.1 36.0 53 59 A L E -F 90 0C 2 4,-0.5 3,-0.3 -2,-0.3 37,-0.2 -0.707 57.4 -64.4 -87.8 134.9 9.7 69.9 39.4 54 60 A E S S- 0 0 83 35,-2.3 -1,-0.2 -2,-0.4 36,-0.0 0.380 112.6 -11.1 -15.2 142.9 6.0 69.7 39.9 55 61 A D S S+ 0 0 154 -3,-0.1 -1,-0.2 1,-0.1 -2,-0.0 0.696 112.5 100.5 17.6 66.2 4.1 73.0 39.7 56 62 A E S S- 0 0 74 -3,-0.3 2,-0.2 0, 0.0 -1,-0.1 -0.824 79.9 -69.4-150.8-174.1 7.2 75.2 39.8 57 63 A P - 0 0 85 0, 0.0 -4,-0.5 0, 0.0 2,-0.2 -0.520 48.8-106.4 -88.3 159.9 9.2 77.0 37.1 58 64 A W - 0 0 94 -2,-0.2 2,-0.4 -6,-0.1 -6,-0.2 -0.521 35.1-163.8 -79.2 149.1 11.3 75.4 34.5 59 65 A K E -G 51 0C 71 -8,-2.8 -8,-2.6 -2,-0.2 2,-0.4 -0.997 16.1-129.2-137.0 141.7 15.1 75.5 34.9 60 66 A L E -G 50 0C 137 -2,-0.4 2,-0.4 -10,-0.2 -10,-0.3 -0.757 19.6-143.9 -93.1 132.5 17.9 74.9 32.4 61 67 A b E -G 49 0C 12 -12,-2.3 -12,-0.6 -2,-0.4 18,-0.1 -0.764 21.6-118.0 -91.6 133.9 20.6 72.5 33.5 62 68 A R - 0 0 108 -2,-0.4 2,-0.3 16,-0.2 16,-0.1 -0.416 40.3-125.6 -63.8 156.1 24.1 73.3 32.4 63 69 A L - 0 0 44 -16,-0.1 2,-0.5 14,-0.1 14,-0.2 -0.805 14.8-148.8-111.0 153.7 25.3 70.5 30.2 64 70 A H E -C 76 0A 74 12,-1.6 12,-1.4 -2,-0.3 2,-0.4 -0.923 8.7-169.9-126.8 113.1 28.3 68.2 30.2 65 71 A Q E +C 75 0A 87 -2,-0.5 10,-0.2 10,-0.2 8,-0.0 -0.772 16.3 164.8 -96.5 136.3 29.9 66.7 27.2 66 72 A A E -C 74 0A 28 8,-2.1 8,-5.4 -2,-0.4 2,-0.8 -0.981 38.3-114.4-155.4 142.1 32.5 64.0 27.6 67 73 A P E -C 73 0A 108 0, 0.0 6,-0.3 0, 0.0 5,-0.1 -0.661 32.6-152.5 -80.4 106.0 34.2 61.4 25.4 68 74 A T > - 0 0 20 4,-2.4 3,-1.2 -2,-0.8 -62,-0.0 -0.233 27.6-106.3 -72.4 165.0 33.4 57.8 26.5 69 75 A A T 3 S+ 0 0 104 1,-0.3 2,-0.3 2,-0.1 -1,-0.1 0.931 116.6 62.7 -55.1 -52.4 35.7 54.8 25.9 70 76 A R T 3 S- 0 0 229 1,-0.2 -1,-0.3 -33,-0.0 2,-0.3 0.221 122.6-104.4 -63.3 18.7 33.6 53.4 23.1 71 77 A G S < S+ 0 0 61 -3,-1.2 -1,-0.2 -2,-0.3 -2,-0.1 -0.035 85.4 119.5 84.6 -33.5 34.3 56.6 21.2 72 78 A A - 0 0 12 -2,-0.3 -4,-2.4 -35,-0.2 2,-0.4 -0.055 64.6-113.6 -62.7 164.6 30.9 58.1 21.7 73 79 A V E -BC 36 67A 16 -37,-1.6 -37,-1.3 -6,-0.3 2,-0.4 -0.807 24.2-141.9-103.0 145.9 30.3 61.4 23.5 74 80 A R E -BC 35 66A 19 -8,-5.4 -8,-2.1 -2,-0.4 2,-0.4 -0.896 10.4-166.0-113.2 135.7 28.5 61.6 26.8 75 81 A F E +BC 34 65A 5 -41,-1.5 -41,-1.2 -2,-0.4 2,-0.3 -0.968 17.7 169.3-117.0 131.3 26.1 64.4 27.9 76 82 A W E -BC 33 64A 38 -12,-1.4 -12,-1.6 -2,-0.4 2,-0.4 -0.985 23.0-161.0-144.4 155.8 25.1 64.6 31.5 77 83 A b E -B 32 0A 0 -45,-1.6 -45,-1.1 -2,-0.3 2,-0.9 -0.934 7.9-157.7-139.8 109.1 23.3 67.0 33.9 78 84 A S E -B 31 0A 54 -2,-0.4 -47,-0.3 -47,-0.2 -16,-0.2 -0.806 30.3-128.9 -86.0 109.6 23.8 66.8 37.7 79 85 A L - 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