==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=26-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GROWTH FACTOR/GROWTH FACTOR RECEPTOR 24-AUG-99 1CVS . COMPND 2 MOLECULE: FIBROBLAST GROWTH FACTOR 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.N.PLOTNIKOV,J.SCHLESSINGER,S.R.HUBBARD,M.MOHAMMADI . 665 5 4 3 1 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 29400.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 452 68.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 20 3.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 234 35.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 12 1.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 11 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 83 12.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 71 10.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 11 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 13 10 4 9 4 7 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 6 2 0 4 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A H > 0 0 113 0, 0.0 3,-1.3 0, 0.0 391,-0.1 0.000 360.0 360.0 360.0 119.3 69.8 28.9 136.5 2 17 A F T 3 + 0 0 3 1,-0.3 38,-0.2 391,-0.2 430,-0.1 0.696 360.0 64.0 -57.7 -24.7 68.0 26.0 134.9 3 18 A K T 3 S+ 0 0 21 429,-0.1 -1,-0.3 2,-0.1 430,-0.2 0.807 92.2 77.0 -71.2 -31.1 64.6 27.6 135.5 4 19 A D S < S- 0 0 75 -3,-1.3 36,-0.3 1,-0.1 2,-0.0 -0.316 93.2 -91.0 -80.5 161.2 65.3 30.6 133.2 5 20 A P - 0 0 31 0, 0.0 124,-2.3 0, 0.0 2,-0.3 -0.367 40.5-150.9 -70.0 153.1 65.3 30.7 129.4 6 21 A K E -AB 38 128A 16 32,-2.8 32,-2.7 122,-0.2 2,-0.5 -0.867 8.6-135.1-123.8 155.9 68.4 30.0 127.6 7 22 A R E -AB 37 127A 26 120,-3.0 120,-1.7 -2,-0.3 2,-0.9 -0.948 18.5-141.1-110.1 129.4 69.8 31.1 124.2 8 23 A L E - B 0 126A 3 28,-0.5 9,-2.5 -2,-0.5 2,-0.6 -0.804 14.9-166.6 -98.0 106.0 71.3 28.4 122.0 9 24 A Y E -CB 16 125A 2 116,-2.5 116,-2.6 -2,-0.9 2,-0.4 -0.781 15.8-138.9 -90.3 117.3 74.4 29.6 120.2 10 25 A C E > - B 0 124A 0 5,-3.1 4,-1.5 -2,-0.6 5,-0.4 -0.622 5.1-142.4 -80.9 131.5 75.5 27.2 117.4 11 26 A K T 4 S+ 0 0 21 112,-3.1 2,-1.5 -2,-0.4 110,-0.2 0.786 89.3 79.7 -60.2 -26.9 79.2 26.6 117.1 12 27 A N T 4 S- 0 0 13 111,-0.5 3,-0.2 108,-0.5 95,-0.2 -0.598 123.6 -21.7 -88.2 81.0 78.7 26.6 113.3 13 28 A G T 4 S- 0 0 15 -2,-1.5 -1,-0.2 1,-0.2 -2,-0.2 0.226 97.2 -91.4 108.1 -14.1 78.5 30.2 112.4 14 29 A G S < S+ 0 0 4 -4,-1.5 2,-0.4 1,-0.3 -3,-0.2 0.784 74.4 158.3 77.5 25.0 77.5 31.7 115.7 15 30 A F - 0 0 20 -5,-0.4 -5,-3.1 -3,-0.2 2,-0.4 -0.721 36.8-138.9 -88.1 130.9 73.9 31.4 114.9 16 31 A F E -CD 9 28A 0 12,-2.7 12,-1.4 -2,-0.4 -7,-0.2 -0.735 30.3-107.9 -85.1 132.2 71.3 31.4 117.7 17 32 A L E - D 0 27A 1 -9,-2.5 2,-0.4 -2,-0.4 -9,-0.3 -0.413 42.5-161.0 -62.7 130.5 68.5 28.8 117.2 18 33 A R E - D 0 26A 40 8,-3.5 8,-2.0 -2,-0.1 2,-0.6 -0.946 18.1-163.0-122.7 137.7 65.4 30.7 116.4 19 34 A I E - D 0 25A 0 16,-2.3 36,-0.5 -2,-0.4 6,-0.2 -0.914 17.5-148.2-120.7 104.9 61.7 29.8 116.6 20 35 A H > - 0 0 22 4,-2.3 3,-2.8 -2,-0.6 49,-0.1 -0.383 23.1-119.4 -68.9 143.8 59.4 32.0 114.7 21 36 A P T 3 S+ 0 0 60 0, 0.0 -1,-0.1 0, 0.0 31,-0.0 0.754 114.6 61.6 -54.5 -24.5 55.8 32.5 116.0 22 37 A D T 3 S- 0 0 84 2,-0.1 -2,-0.1 35,-0.0 47,-0.0 0.399 124.4-102.0 -84.6 2.7 54.6 31.0 112.7 23 38 A G S < S+ 0 0 10 -3,-2.8 46,-2.4 1,-0.3 2,-0.1 0.370 77.0 136.5 94.3 -5.9 56.4 27.7 113.5 24 39 A R - 0 0 155 44,-0.2 -4,-2.3 -5,-0.0 2,-0.4 -0.476 40.2-150.2 -76.1 149.7 59.4 28.2 111.2 25 40 A V E +D 19 0A 9 42,-0.4 84,-0.6 -6,-0.2 2,-0.2 -0.980 34.8 119.3-124.7 131.3 62.8 27.3 112.6 26 41 A D E -DE 18 108A 35 -8,-2.0 -8,-3.5 -2,-0.4 2,-0.3 -0.870 48.6 -88.1-162.9-164.8 66.2 28.9 111.6 27 42 A G E -D 17 0A 6 80,-2.2 2,-0.3 -2,-0.2 -10,-0.2 -0.850 24.9-178.7-126.5 162.1 69.2 30.8 113.0 28 43 A V E -D 16 0A 18 -12,-1.4 -12,-2.7 -2,-0.3 5,-0.1 -0.952 23.9-150.2-157.3 136.6 70.3 34.3 113.6 29 44 A R S S+ 0 0 84 -2,-0.3 2,-1.0 -14,-0.2 -1,-0.1 0.735 70.4 104.9 -80.4 -20.6 73.4 35.9 115.0 30 45 A E > - 0 0 110 1,-0.2 3,-2.6 -14,-0.1 -1,-0.1 -0.456 56.1-162.4 -68.5 101.5 71.6 38.9 116.4 31 46 A K T 3 S+ 0 0 66 -2,-1.0 -1,-0.2 1,-0.3 5,-0.1 0.709 87.9 60.9 -55.4 -22.6 71.5 38.3 120.2 32 47 A S T 3 S+ 0 0 96 3,-0.0 -1,-0.3 4,-0.0 -2,-0.1 0.459 73.2 132.2 -87.9 2.2 68.6 40.8 120.5 33 48 A D X - 0 0 24 -3,-2.6 3,-1.1 1,-0.1 4,-0.2 -0.273 57.9-137.8 -53.3 132.4 66.3 38.8 118.3 34 49 A P T 3 S+ 0 0 84 0, 0.0 3,-0.4 0, 0.0 20,-0.2 0.766 95.2 52.0 -66.4 -25.7 62.9 38.5 119.9 35 50 A H T 3 S+ 0 0 42 1,-0.2 -16,-2.3 19,-0.1 20,-0.1 0.086 86.2 80.8-102.9 23.6 62.4 34.8 119.0 36 51 A I < + 0 0 0 -3,-1.1 2,-0.7 -18,-0.2 -28,-0.5 0.510 58.0 106.2-107.8 -0.1 65.6 33.2 120.3 37 52 A K E -A 7 0A 94 -3,-0.4 16,-2.1 -4,-0.2 17,-0.5 -0.684 54.2-169.6 -80.7 115.0 64.8 32.9 124.0 38 53 A L E -AF 6 52A 0 -32,-2.7 -32,-2.8 -2,-0.7 2,-0.6 -0.756 21.0-144.9-107.4 150.3 64.2 29.2 124.5 39 54 A Q E - F 0 51A 26 12,-2.7 12,-2.1 -2,-0.3 2,-0.5 -0.933 16.1-158.9-117.3 104.1 62.8 27.3 127.6 40 55 A L E - F 0 50A 0 -2,-0.6 2,-0.4 -36,-0.3 10,-0.2 -0.737 12.7-174.7 -84.8 124.1 64.4 23.9 127.9 41 56 A Q E - F 0 49A 7 8,-2.3 8,-2.3 -2,-0.5 2,-0.4 -0.975 19.9-133.0-123.1 135.5 62.3 21.6 130.0 42 57 A A E - F 0 48A 1 -2,-0.4 6,-0.3 355,-0.4 357,-0.1 -0.725 17.0-176.1 -87.9 134.7 63.4 18.1 131.1 43 58 A E E S- 0 0 55 4,-2.7 2,-0.3 1,-0.5 -1,-0.2 0.677 77.1 -27.4 -97.1 -23.5 60.8 15.4 130.5 44 59 A E E > S- F 0 47A 97 3,-1.1 3,-2.5 412,-0.0 -1,-0.5 -0.937 104.1 -35.6-173.7 173.3 63.1 12.9 132.2 45 60 A R T 3 S- 0 0 106 1,-0.3 412,-0.2 -2,-0.3 3,-0.1 -0.177 128.8 -2.9 -48.3 123.6 66.9 12.5 132.8 46 61 A G T 3 S+ 0 0 13 350,-0.4 35,-1.0 410,-0.3 2,-0.4 0.593 111.0 105.6 69.3 13.5 68.7 13.6 129.7 47 62 A V E < +FG 44 80A 3 -3,-2.5 -4,-2.7 33,-0.2 -3,-1.1 -0.986 42.7 174.0-130.4 126.3 65.6 14.5 127.7 48 63 A V E -FG 42 79A 1 31,-2.7 31,-2.5 -2,-0.4 2,-0.4 -0.915 26.7-143.0-131.5 157.0 64.3 18.0 127.0 49 64 A S E -F 41 0A 1 -8,-2.3 -8,-2.3 -2,-0.3 2,-0.7 -0.913 24.3-140.0-111.0 139.9 61.6 19.7 125.0 50 65 A I E -F 40 0A 1 27,-0.4 9,-3.1 -2,-0.4 2,-0.5 -0.918 20.2-169.3-107.4 111.3 62.7 23.0 123.5 51 66 A K E -FH 39 58A 49 -12,-2.1 -12,-2.7 -2,-0.7 2,-0.8 -0.888 20.6-135.6-107.7 126.3 60.0 25.6 123.7 52 67 A G E >> -FH 38 57A 1 5,-3.3 4,-2.0 -2,-0.5 5,-0.9 -0.662 15.3-156.8 -75.9 112.6 60.2 29.0 122.0 53 68 A V T 45S+ 0 0 69 -16,-2.1 -1,-0.2 -2,-0.8 -15,-0.1 0.894 89.7 40.5 -58.3 -45.0 59.1 31.5 124.6 54 69 A S T 45S+ 0 0 63 -17,-0.5 -1,-0.2 -20,-0.2 -19,-0.1 0.974 123.1 38.7 -68.6 -54.9 58.1 34.2 122.1 55 70 A A T 45S- 0 0 9 -36,-0.5 -2,-0.2 2,-0.1 -1,-0.2 0.644 95.4-140.7 -71.1 -14.6 56.5 31.8 119.6 56 71 A N T <5 + 0 0 84 -4,-2.0 2,-0.3 1,-0.2 -3,-0.2 0.932 60.7 123.0 51.7 46.9 55.0 29.6 122.3 57 72 A R E < -H 52 0A 42 -5,-0.9 -5,-3.3 -38,-0.1 2,-0.5 -0.947 61.0-120.7-135.5 158.5 55.8 26.5 120.2 58 73 A Y E -HI 51 70A 30 12,-2.7 12,-2.5 -2,-0.3 -7,-0.2 -0.863 28.1-115.3-106.3 129.6 57.9 23.4 120.7 59 74 A L E - I 0 69A 0 -9,-3.1 -9,-0.4 -2,-0.5 2,-0.4 -0.396 41.4-171.9 -60.1 130.8 60.9 22.5 118.5 60 75 A A E - I 0 68A 1 8,-3.5 8,-1.5 -2,-0.1 2,-0.5 -0.987 22.5-145.6-135.8 143.0 60.1 19.3 116.6 61 76 A M E - I 0 67A 0 15,-1.7 6,-0.2 -2,-0.4 2,-0.2 -0.882 24.1-145.1-102.2 130.8 62.0 16.9 114.3 62 77 A K > - 0 0 45 4,-2.1 3,-2.4 -2,-0.5 50,-0.1 -0.553 28.7-100.1 -96.9 163.3 60.0 15.4 111.5 63 78 A E T 3 S+ 0 0 145 1,-0.3 -1,-0.1 -2,-0.2 -2,-0.0 0.786 125.2 46.8 -49.5 -34.8 60.3 11.9 110.0 64 79 A D T 3 S- 0 0 72 2,-0.1 49,-0.5 48,-0.0 -1,-0.3 0.510 124.4-102.6 -87.6 -6.5 62.3 13.2 107.1 65 80 A G S < S+ 0 0 0 -3,-2.4 47,-3.0 1,-0.3 2,-0.3 0.666 73.8 137.5 96.5 17.4 64.5 15.3 109.4 66 81 A R - 0 0 84 45,-0.2 -4,-2.1 46,-0.1 -1,-0.3 -0.725 45.6-130.3 -97.0 149.3 63.1 18.8 108.9 67 82 A L E +I 61 0A 6 -2,-0.3 -42,-0.4 -6,-0.2 2,-0.3 -0.664 35.0 149.5 -97.9 154.8 62.6 21.1 111.9 68 83 A L E -I 60 0A 47 -8,-1.5 -8,-3.5 -2,-0.3 2,-0.6 -0.942 44.4-108.6-168.4 165.5 59.6 23.1 112.8 69 84 A A E -I 59 0A 1 -46,-2.4 -10,-0.3 -2,-0.3 -18,-0.0 -0.908 31.7-146.9-115.4 108.1 57.9 24.3 116.0 70 85 A S E -I 58 0A 21 -12,-2.5 -12,-2.7 -2,-0.6 -47,-0.1 -0.253 12.5-134.9 -67.4 152.9 54.7 22.6 116.9 71 86 A K S S+ 0 0 130 -14,-0.2 2,-0.3 1,-0.1 -1,-0.1 0.908 91.9 22.9 -75.6 -43.1 51.9 24.4 118.7 72 87 A S S S- 0 0 80 -14,-0.1 2,-0.2 -15,-0.1 -1,-0.1 -0.854 100.7 -86.2-121.6 158.4 51.4 21.6 121.2 73 88 A V + 0 0 49 -2,-0.3 2,-0.2 -3,-0.1 -13,-0.0 -0.427 48.1 168.9 -70.5 131.2 53.7 18.9 122.4 74 89 A T > - 0 0 50 -2,-0.2 3,-1.1 -16,-0.0 -4,-0.0 -0.609 53.4 -87.9-124.3-173.2 54.0 15.7 120.3 75 90 A D T 3 S+ 0 0 83 1,-0.2 3,-0.4 -2,-0.2 20,-0.1 0.478 122.1 64.1 -82.0 1.6 56.4 12.8 120.5 76 91 A E T 3 S+ 0 0 24 1,-0.2 -15,-1.7 18,-0.1 -1,-0.2 0.345 83.3 80.1-101.1 3.7 58.8 14.6 118.1 77 92 A C S < S+ 0 0 0 -3,-1.1 -27,-0.4 -17,-0.2 2,-0.4 0.220 74.7 91.5 -95.6 15.4 59.4 17.4 120.6 78 93 A F + 0 0 18 -3,-0.4 16,-2.5 -29,-0.2 17,-0.5 -0.908 49.7 179.2-117.4 139.1 61.9 15.5 122.8 79 94 A F E -GJ 48 93A 0 -31,-2.5 -31,-2.7 -2,-0.4 2,-1.0 -0.959 34.8-112.4-137.1 153.8 65.7 15.5 122.4 80 95 A F E -GJ 47 92A 51 12,-3.5 12,-1.5 -2,-0.3 2,-0.7 -0.751 31.6-154.1 -85.9 102.9 68.7 14.0 124.2 81 96 A E E + J 0 91A 4 -35,-1.0 2,-0.4 -2,-1.0 377,-0.2 -0.715 22.2 175.7 -80.8 115.1 70.4 16.9 125.7 82 97 A R E - J 0 90A 134 8,-2.1 8,-1.6 -2,-0.7 2,-1.1 -0.982 31.0-144.7-129.2 126.3 74.1 15.8 126.0 83 98 A L E - J 0 89A 21 -2,-0.4 6,-0.2 6,-0.2 -2,-0.0 -0.757 33.0-147.5 -85.9 99.1 77.0 17.9 127.2 84 99 A E > - 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