==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=24-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER IMMUNE SYSTEM/PEPTIDE INHIBITOR 07-OCT-99 1D5M . COMPND 2 MOLECULE: HLA CLASS II HISTOCOMPATIBILITY ANTIGEN; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.L.SWAIN,R.CROWTHER,U.KAMMLOTT . 592 6 4 3 1 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 27637.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 416 70.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 2.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 194 32.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 4 0.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 8 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 68 11.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 49 8.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 74 12.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 1 1 4 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 4 5 3 2 7 0 3 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 1 2 4 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A E 0 0 118 0, 0.0 2,-0.3 0, 0.0 195,-0.2 0.000 360.0 360.0 360.0 113.5 5.7 42.2 25.1 2 5 A H E -A 195 0A 40 193,-1.8 193,-3.5 196,-0.1 2,-0.4 -0.987 360.0-152.8-149.1 154.0 9.4 41.3 24.7 3 6 A V E -A 194 0A 26 -2,-0.3 21,-2.6 191,-0.2 2,-0.5 -0.995 4.6-170.2-134.3 126.3 11.5 38.4 23.5 4 7 A I E -AB 193 23A 5 189,-2.4 189,-2.5 -2,-0.4 2,-0.4 -0.976 13.9-170.8-114.8 126.6 15.0 37.6 24.5 5 8 A I E -AB 192 22A 22 17,-2.8 17,-2.8 -2,-0.5 2,-0.9 -0.972 20.8-158.4-125.4 129.1 16.6 34.9 22.4 6 9 A Q E -AB 191 21A 0 185,-2.6 185,-2.3 -2,-0.4 2,-0.4 -0.910 29.5-170.4 -98.9 106.4 19.9 33.0 23.0 7 10 A A E +AB 190 20A 6 13,-2.5 13,-2.5 -2,-0.9 2,-0.3 -0.852 11.5 172.8-108.1 141.7 20.7 31.8 19.5 8 11 A E E +AB 189 19A 2 181,-2.5 181,-2.1 -2,-0.4 2,-0.3 -0.933 4.4 175.4-139.1 156.9 23.4 29.4 18.4 9 12 A F E -AB 188 18A 8 9,-1.5 9,-1.8 -2,-0.3 2,-0.4 -0.967 13.3-160.9-160.6 151.3 24.4 27.6 15.3 10 13 A Y E -AB 187 17A 0 177,-1.9 177,-2.1 -2,-0.3 2,-0.4 -0.994 16.5-156.0-136.8 132.1 27.2 25.3 14.1 11 14 A L E >> -AB 186 16A 0 5,-3.2 4,-1.7 -2,-0.4 5,-1.3 -0.929 11.7-122.6-120.0 133.5 28.0 24.8 10.4 12 15 A N E 45S+A 185 0A 26 173,-2.6 173,-2.2 -2,-0.4 -2,-0.0 -0.884 84.3 9.0-113.8 150.9 29.7 22.0 8.6 13 16 A P T 45S+ 0 0 43 0, 0.0 -1,-0.2 0, 0.0 171,-0.1 -0.963 125.4 60.5 -86.5 8.5 32.0 21.6 6.8 14 17 A D T 45S- 0 0 32 2,-0.1 393,-0.2 1,-0.1 -2,-0.2 0.752 89.3-146.2 -64.6 -23.0 33.0 25.2 7.6 15 18 A Q T <5 + 0 0 26 -4,-1.7 392,-2.4 1,-0.2 2,-0.3 0.936 51.1 134.1 52.9 50.0 33.3 24.2 11.2 16 19 A S E < +B 11 0A 23 -5,-1.3 -5,-3.2 390,-0.2 2,-0.3 -0.877 28.9 174.9-124.8 156.8 32.1 27.7 12.3 17 20 A G E -B 10 0A 23 -2,-0.3 2,-0.3 -7,-0.2 -7,-0.2 -0.893 15.9-146.5-151.0-178.9 29.6 28.7 14.8 18 21 A E E -B 9 0A 14 -9,-1.8 -9,-1.5 -2,-0.3 2,-0.4 -0.979 5.0-169.6-158.6 146.0 28.0 31.5 16.7 19 22 A F E +B 8 0A 0 12,-0.4 12,-2.3 -2,-0.3 2,-0.3 -0.982 27.8 149.2-139.1 120.3 26.5 32.2 20.1 20 23 A M E -BC 7 30A 0 -13,-2.5 -13,-2.5 -2,-0.4 2,-0.4 -0.983 39.7-127.8-152.1 161.6 24.5 35.4 20.6 21 24 A F E -BC 6 29A 1 8,-2.4 7,-2.9 -2,-0.3 8,-1.0 -0.934 23.9-164.1-112.5 137.7 21.7 37.0 22.6 22 25 A D E -BC 5 27A 6 -17,-2.8 -17,-2.8 -2,-0.4 2,-0.5 -0.948 6.9-165.0-123.7 138.3 18.9 38.9 20.8 23 26 A F E > S-BC 4 26A 0 3,-3.5 3,-2.1 -2,-0.4 -19,-0.2 -0.947 78.4 -27.2-127.3 111.5 16.4 41.3 22.3 24 27 A D T 3 S- 0 0 55 -21,-2.6 -20,-0.1 -2,-0.5 -1,-0.1 0.904 128.9 -46.6 50.4 45.0 13.4 42.1 20.2 25 28 A G T 3 S+ 0 0 18 -22,-0.3 2,-0.4 1,-0.2 -1,-0.3 0.291 118.8 109.3 84.7 -11.1 15.4 41.4 17.0 26 29 A D E < S-C 23 0A 1 -3,-2.1 -3,-3.5 297,-0.1 2,-0.3 -0.822 71.8-114.7-103.1 140.3 18.4 43.4 18.1 27 30 A E E -C 22 0A 3 -2,-0.4 -5,-0.3 295,-0.3 3,-0.1 -0.525 24.9-177.7 -74.1 127.5 21.8 41.8 19.1 28 31 A I E - 0 0 1 -7,-2.9 13,-2.6 1,-0.4 14,-0.5 0.872 68.5 -40.5 -86.3 -45.2 22.8 42.4 22.7 29 32 A F E -CD 21 40A 0 -8,-1.0 -8,-2.4 11,-0.3 -1,-0.4 -0.975 47.5-149.5-170.6 167.7 26.1 40.5 22.2 30 33 A H E -CD 20 39A 35 9,-1.5 9,-2.7 -2,-0.3 2,-0.5 -0.949 29.4-110.6-143.5 157.0 27.9 37.5 20.6 31 34 A V E - D 0 38A 6 -12,-2.3 2,-1.0 -2,-0.3 -12,-0.4 -0.820 15.9-140.9 -96.3 129.8 30.9 35.5 21.8 32 35 A D E >> - D 0 37A 47 5,-2.6 4,-2.0 -2,-0.5 5,-1.2 -0.803 18.6-165.1 -85.0 106.5 34.1 35.8 19.8 33 36 A M T 45S+ 0 0 14 -2,-1.0 -1,-0.2 2,-0.2 373,-0.1 0.716 80.9 50.8 -71.7 -19.6 35.1 32.2 20.0 34 37 A A T 45S+ 0 0 32 1,-0.1 -1,-0.2 -3,-0.1 -2,-0.1 0.934 122.4 29.9 -81.3 -49.4 38.7 32.7 18.9 35 38 A K T 45S- 0 0 116 2,-0.1 -2,-0.2 395,-0.0 -1,-0.1 0.697 102.5-135.0 -81.3 -17.8 39.5 35.5 21.4 36 39 A K T <5 + 0 0 5 -4,-2.0 2,-0.3 1,-0.2 18,-0.3 0.967 57.1 130.3 61.9 56.1 37.0 34.0 23.9 37 40 A E E < -D 32 0A 87 -5,-1.2 -5,-2.6 16,-0.2 2,-0.5 -0.966 63.8-111.7-138.3 155.2 35.4 37.4 24.8 38 41 A T E -D 31 0A 29 -2,-0.3 2,-0.8 -7,-0.2 -7,-0.2 -0.755 29.4-157.0 -86.7 124.5 31.9 38.8 25.0 39 42 A V E -D 30 0A 53 -9,-2.7 -9,-1.5 -2,-0.5 2,-0.2 -0.884 8.6-151.0-107.1 102.9 31.4 41.4 22.3 40 43 A W E -D 29 0A 53 -2,-0.8 -11,-0.3 -11,-0.2 -12,-0.1 -0.502 12.6-138.0 -73.7 139.4 28.7 43.8 23.2 41 44 A R S S+ 0 0 54 -13,-2.6 2,-0.4 -2,-0.2 -1,-0.1 0.867 93.7 24.2 -64.5 -37.7 26.7 45.3 20.4 42 45 A L S >> S- 0 0 38 -14,-0.5 3,-0.7 1,-0.1 4,-0.6 -0.962 81.9-125.6-126.4 145.9 26.8 48.7 22.1 43 46 A E H >> S+ 0 0 163 -2,-0.4 3,-1.1 1,-0.2 4,-0.5 0.909 105.8 64.8 -55.0 -47.3 29.4 49.9 24.6 44 47 A E H >> S+ 0 0 65 1,-0.3 3,-1.9 2,-0.2 4,-0.8 0.849 91.7 65.7 -45.2 -42.3 26.8 50.8 27.2 45 48 A F H X> S+ 0 0 0 -3,-0.7 4,-1.2 1,-0.3 3,-1.2 0.888 97.5 51.9 -50.3 -48.0 25.8 47.1 27.5 46 49 A G H << S+ 0 0 34 -3,-1.1 -1,-0.3 -4,-0.6 -2,-0.2 0.567 103.1 60.3 -69.6 -8.3 29.1 46.0 29.0 47 50 A R H << S+ 0 0 183 -3,-1.9 -1,-0.2 -4,-0.5 -2,-0.2 0.681 115.1 32.3 -90.3 -19.1 29.0 48.7 31.6 48 51 A F H << S+ 0 0 103 -3,-1.2 2,-0.3 -4,-0.8 -2,-0.2 0.501 123.1 25.8-116.1 -5.2 25.8 47.3 33.1 49 52 A A < - 0 0 16 -4,-1.2 2,-0.3 215,-0.1 -1,-0.1 -0.957 57.9-154.5-151.3 167.6 26.0 43.6 32.6 50 53 A S - 0 0 87 -2,-0.3 2,-0.3 -3,-0.1 -3,-0.0 -0.924 2.8-167.6-141.5 164.4 28.4 40.7 32.1 51 54 A F - 0 0 22 -2,-0.3 2,-1.4 -5,-0.1 -13,-0.2 -0.947 29.6-121.7-154.7 135.1 28.5 37.3 30.5 52 55 A E > - 0 0 90 539,-0.4 3,-1.0 -2,-0.3 4,-0.5 -0.657 29.4-169.5 -83.1 93.5 31.1 34.5 30.9 53 56 A A G > S+ 0 0 4 -2,-1.4 3,-1.7 1,-0.2 4,-0.4 0.835 76.4 61.5 -49.6 -46.3 32.0 34.1 27.2 54 57 A Q G > S+ 0 0 3 -18,-0.3 3,-1.5 1,-0.3 4,-0.4 0.825 92.6 65.1 -58.6 -31.8 34.0 30.9 27.6 55 58 A G G X> S+ 0 0 23 -3,-1.0 3,-1.3 1,-0.3 4,-0.8 0.773 88.4 71.1 -61.2 -25.0 31.0 29.0 28.8 56 59 A A H <> S+ 0 0 0 -3,-1.7 4,-1.9 -4,-0.5 3,-0.3 0.782 84.2 67.2 -61.3 -30.3 29.5 29.5 25.4 57 60 A L H <> S+ 0 0 1 -3,-1.5 4,-2.4 -4,-0.4 -1,-0.3 0.801 92.1 62.0 -62.5 -28.0 31.9 27.1 23.8 58 61 A A H <> S+ 0 0 30 -3,-1.3 4,-1.8 -4,-0.4 -1,-0.2 0.925 104.8 46.9 -62.7 -44.6 30.2 24.3 25.8 59 62 A N H X S+ 0 0 10 -4,-0.8 4,-2.6 -3,-0.3 -2,-0.2 0.927 112.7 47.8 -62.0 -48.9 27.0 25.0 23.9 60 63 A I H X S+ 0 0 0 -4,-1.9 4,-2.1 2,-0.2 -1,-0.2 0.875 107.9 56.4 -62.0 -36.8 28.7 25.1 20.5 61 64 A A H X S+ 0 0 9 -4,-2.4 4,-1.8 1,-0.2 -1,-0.2 0.920 111.4 43.3 -60.4 -43.4 30.5 21.9 21.3 62 65 A V H X S+ 0 0 45 -4,-1.8 4,-2.7 1,-0.2 -2,-0.2 0.890 109.9 57.0 -69.3 -37.5 27.2 20.2 21.9 63 66 A D H X S+ 0 0 0 -4,-2.6 4,-1.9 1,-0.2 -2,-0.2 0.861 106.4 49.3 -63.2 -34.6 25.7 21.9 18.8 64 67 A K H X S+ 0 0 2 -4,-2.1 4,-2.0 2,-0.2 -1,-0.2 0.938 110.9 50.4 -67.4 -45.9 28.4 20.3 16.7 65 68 A A H X S+ 0 0 29 -4,-1.8 4,-1.7 1,-0.2 -2,-0.2 0.907 111.4 47.9 -58.3 -43.7 27.7 16.9 18.2 66 69 A N H X S+ 0 0 17 -4,-2.7 4,-3.1 1,-0.2 5,-0.2 0.862 107.8 55.8 -66.7 -35.9 24.0 17.3 17.6 67 70 A L H X S+ 0 0 0 -4,-1.9 4,-3.1 -5,-0.2 -1,-0.2 0.893 105.5 51.7 -62.6 -40.3 24.6 18.3 14.0 68 71 A E H X S+ 0 0 50 -4,-2.0 4,-1.7 2,-0.2 -1,-0.2 0.928 113.3 44.7 -63.2 -43.1 26.6 15.2 13.4 69 72 A I H X S+ 0 0 82 -4,-1.7 4,-2.4 2,-0.2 -2,-0.2 0.936 117.2 43.8 -66.6 -46.9 23.7 13.1 14.7 70 73 A M H X S+ 0 0 3 -4,-3.1 4,-2.5 2,-0.2 -2,-0.2 0.903 107.2 60.2 -67.6 -38.1 21.0 15.0 12.8 71 74 A T H <>S+ 0 0 11 -4,-3.1 5,-2.9 -5,-0.2 6,-0.5 0.951 111.6 40.5 -53.4 -49.6 23.1 15.0 9.6 72 75 A K H ><5S+ 0 0 132 -4,-1.7 3,-2.2 3,-0.2 -1,-0.2 0.918 111.4 56.7 -64.6 -45.7 23.0 11.2 9.6 73 76 A R H 3<5S+ 0 0 86 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.860 106.6 49.4 -54.7 -39.2 19.4 11.0 10.7 74 77 A S T 3<5S- 0 0 16 -4,-2.5 -1,-0.3 -5,-0.1 -2,-0.2 0.408 122.2-110.7 -80.6 2.9 18.3 13.1 7.8 75 78 A N T < 5S- 0 0 132 -3,-2.2 -3,-0.2 1,-0.2 -2,-0.2 0.934 71.1 -57.6 65.3 45.8 20.4 10.7 5.6 76 79 A Y S - 0 0 104 -2,-0.4 3,-2.0 3,-0.3 -3,-0.0 -0.983 43.3 -95.6-127.7 140.0 21.9 66.0 2.1 96 99 A L T 3 S- 0 0 71 -2,-0.4 57,-0.2 1,-0.3 55,-0.0 -0.289 106.4 -1.5 -57.0 134.0 24.9 66.9 0.0 97 100 A R T 3 S+ 0 0 186 55,-2.5 -1,-0.3 1,-0.2 56,-0.1 0.530 101.3 129.8 62.8 6.4 28.1 67.1 2.0 98 101 A E < - 0 0 97 -3,-2.0 -3,-0.3 1,-0.1 -1,-0.2 -0.817 69.6-103.7 -95.9 125.4 26.2 66.2 5.1 99 102 A P + 0 0 94 0, 0.0 2,-0.2 0, 0.0 52,-0.2 -0.155 57.2 153.4 -46.8 130.0 27.6 63.3 7.2 100 103 A N E - J 0 150C 8 50,-2.4 50,-2.5 -6,-0.1 2,-0.4 -0.832 35.6-124.0-147.3-177.1 25.6 60.2 6.8 101 104 A V E - J 0 149C 30 48,-0.3 -10,-1.7 -2,-0.2 2,-0.4 -0.996 11.7-141.0-142.4 134.6 25.8 56.4 6.9 102 105 A L E -IJ 90 148C 0 46,-2.2 46,-1.8 -2,-0.4 2,-0.5 -0.806 17.5-159.8 -93.8 132.6 25.1 53.7 4.3 103 106 A I E -IJ 89 147C 1 -14,-3.7 -14,-2.2 -2,-0.4 2,-0.7 -0.965 4.2-158.8-116.1 124.6 23.5 50.6 5.7 104 107 A a E -IJ 88 146C 0 42,-3.0 42,-1.5 -2,-0.5 2,-0.7 -0.905 8.5-159.7-103.6 111.7 23.6 47.4 3.7 105 108 A F E -IJ 87 145C 25 -18,-3.5 -18,-2.1 -2,-0.7 2,-0.7 -0.834 6.0-170.9 -93.9 114.4 20.9 45.0 4.8 106 109 A I E +IJ 86 144C 1 38,-3.1 38,-2.1 -2,-0.7 2,-0.3 -0.914 26.2 175.4-105.7 108.3 21.6 41.4 3.9 107 110 A D E +I 85 0C 27 -22,-2.7 -22,-2.8 -2,-0.7 36,-0.2 -0.773 35.2 13.1-125.4 161.3 18.4 39.5 4.6 108 111 A K E S+ 0 0 67 -2,-0.3 2,-0.3 -24,-0.2 -1,-0.2 0.923 84.9 133.0 48.2 61.9 16.5 36.2 4.4 109 112 A F E - J 0 142C 0 33,-1.8 33,-2.1 -3,-0.2 -1,-0.2 -0.943 38.0-135.3-141.1 162.1 19.5 34.0 3.6 110 113 A T B +H 82 0B 1 -28,-1.7 -28,-3.0 -2,-0.3 31,-0.1 -0.921 69.1 44.1-169.8 148.7 21.2 30.7 4.5 111 114 A P S S- 0 0 0 0, 0.0 2,-2.3 0, 0.0 -1,-0.1 0.558 84.1-118.0 -69.0 166.4 23.7 29.2 5.1 112 115 A P S S+ 0 0 3 0, 0.0 2,-0.3 0, 0.0 22,-0.1 -0.367 78.5 104.5 -76.4 65.5 25.2 31.8 7.4 113 116 A V + 0 0 32 -2,-2.3 52,-0.4 2,-0.0 2,-0.3 -0.965 37.9 150.1-146.0 125.0 28.4 32.5 5.3 114 117 A V - 0 0 20 -2,-0.3 2,-0.5 50,-0.1 50,-0.2 -0.991 37.0-139.7-153.2 155.5 28.9 35.6 3.2 115 118 A N E -M 163 0D 92 48,-1.8 48,-2.9 -2,-0.3 2,-0.4 -0.993 27.6-172.0-117.2 122.8 31.7 37.9 1.9 116 119 A V E +M 162 0D 26 -2,-0.5 2,-0.4 46,-0.2 46,-0.2 -0.969 7.0 176.0-121.5 135.7 30.6 41.5 1.9 117 120 A T E -M 161 0D 46 44,-2.3 44,-3.6 -2,-0.4 2,-0.5 -0.997 22.8-140.3-138.6 138.7 32.6 44.4 0.4 118 121 A W E -MN 160 125D 7 7,-0.7 7,-2.9 -2,-0.4 2,-0.4 -0.858 20.8-161.4 -97.3 134.2 31.8 48.1 0.1 119 122 A L E -MN 159 124D 20 40,-2.6 40,-1.9 -2,-0.5 2,-0.6 -0.967 9.1-163.0-119.4 134.0 32.8 49.7 -3.2 120 123 A R E > S-MN 158 123D 89 3,-3.0 3,-2.2 -2,-0.4 38,-0.2 -0.973 85.6 -21.2-114.9 115.6 33.3 53.4 -3.7 121 124 A N T 3 S- 0 0 65 36,-2.8 -1,-0.2 -2,-0.6 37,-0.1 0.859 131.6 -50.3 51.4 36.7 33.3 54.2 -7.4 122 125 A G T 3 S+ 0 0 50 35,-0.2 -1,-0.3 1,-0.2 36,-0.1 0.375 116.1 111.7 87.2 -4.7 34.2 50.5 -8.0 123 126 A K E < S-N 120 0D 153 -3,-2.2 -3,-3.0 1,-0.0 -1,-0.2 -0.857 75.4-104.8-106.6 137.7 37.1 50.4 -5.5 124 127 A P E -N 119 0D 99 0, 0.0 2,-0.4 0, 0.0 -5,-0.2 -0.344 38.5-161.7 -58.9 131.1 37.0 48.4 -2.3 125 128 A V E +N 118 0D 18 -7,-2.9 -7,-0.7 1,-0.1 3,-0.0 -0.920 28.0 160.4-117.7 143.9 36.6 50.6 0.7 126 129 A T > + 0 0 111 -2,-0.4 3,-1.1 -9,-0.1 2,-0.5 0.362 33.7 126.4-137.6 -5.5 37.3 49.8 4.4 127 130 A T T 3 S- 0 0 111 1,-0.3 -2,-0.0 21,-0.0 0, 0.0 -0.447 94.3 -16.7 -64.8 110.6 37.6 53.2 6.0 128 131 A G T 3 S+ 0 0 56 -2,-0.5 -1,-0.3 1,-0.2 22,-0.0 0.508 96.2 149.9 74.0 4.1 35.3 53.3 8.9 129 132 A V < + 0 0 50 -3,-1.1 2,-0.3 19,-0.1 -1,-0.2 -0.311 18.3 175.8 -69.3 155.0 33.3 50.3 7.8 130 133 A S E -K 147 0C 59 17,-1.6 17,-3.0 2,-0.0 2,-0.3 -0.953 5.9-172.8-151.6 163.8 31.7 48.0 10.4 131 134 A E E -K 146 0C 119 -2,-0.3 2,-0.2 15,-0.2 15,-0.2 -0.968 18.5-125.1-156.0 168.3 29.4 45.0 10.4 132 135 A T - 0 0 6 13,-2.1 3,-0.1 -2,-0.3 2,-0.0 -0.679 30.0-112.7-112.1 167.2 27.4 42.7 12.6 133 136 A V - 0 0 33 -2,-0.2 2,-0.5 1,-0.1 12,-0.4 -0.086 61.9 -55.6 -83.5-166.0 27.6 38.9 12.8 134 137 A F - 0 0 31 -22,-0.1 10,-0.2 10,-0.1 -1,-0.1 -0.642 56.4-154.7 -81.0 122.2 24.7 36.8 11.6 135 138 A L E -L 143 0C 2 8,-3.1 8,-2.0 -2,-0.5 2,-0.1 -0.764 17.6-115.4 -98.0 138.9 21.4 37.6 13.2 136 139 A P E -L 142 0C 12 0, 0.0 2,-0.3 0, 0.0 6,-0.2 -0.419 23.2-153.8 -73.9 145.5 18.6 35.1 13.6 137 140 A R > - 0 0 50 4,-1.7 3,-1.5 -2,-0.1 -112,-0.0 -0.784 27.7-116.2-112.5 159.6 15.2 35.5 11.8 138 141 A E T 3 S+ 0 0 185 -2,-0.3 -1,-0.1 1,-0.3 4,-0.0 0.742 119.8 53.8 -67.9 -22.3 11.9 34.0 13.0 139 142 A D T 3 S- 0 0 68 2,-0.0 -1,-0.3 3,-0.0 3,-0.1 0.331 121.6-113.9 -91.1 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