==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSPORT PROTEIN 29-OCT-05 2D57 . COMPND 2 MOLECULE: AQUAPORIN-4; . SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; . AUTHOR Y.HIROAKI,K.TANI,A.KAMEGAWA,N.GYOBU,K.NISHIKAWA,H.SUZUKI,T.W . 224 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10999.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 175 78.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 7 3.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 20 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 139 62.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 3.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 1 1 0 0 1 0 2 0 1 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 31 A T > 0 0 145 0, 0.0 3,-4.0 0, 0.0 2,-0.3 0.000 360.0 360.0 360.0 -85.9 24.0 58.1 116.8 2 32 A Q T 3> + 0 0 146 1,-0.3 4,-1.3 2,-0.2 5,-0.2 0.399 360.0 64.9 -0.3 -46.4 21.1 60.1 118.5 3 33 A A H >> S+ 0 0 80 -2,-0.3 4,-1.0 1,-0.2 3,-0.7 0.935 101.9 53.8 -54.3 -38.9 18.7 57.3 117.8 4 34 A F H X> S+ 0 0 37 -3,-4.0 4,-2.4 1,-0.2 3,-0.7 0.903 95.4 65.4 -59.4 -44.7 21.0 55.5 120.2 5 35 A W H 3> S+ 0 0 128 1,-0.3 4,-2.3 2,-0.2 -1,-0.2 0.849 99.8 53.0 -47.6 -39.3 20.6 58.2 122.9 6 36 A K H S+ 0 0 0 -4,-2.6 4,-2.3 2,-0.2 5,-0.9 0.966 119.0 47.8 -57.6 -54.1 14.3 49.2 141.4 20 50 A L H X5S+ 0 0 51 -4,-2.6 4,-1.4 -5,-0.3 -1,-0.2 0.946 120.1 41.2 -49.4 -49.5 12.0 51.9 142.7 21 51 A L H X5S+ 0 0 77 -4,-2.9 4,-1.1 -5,-0.3 -2,-0.2 0.977 122.4 37.5 -64.8 -57.0 9.2 49.6 142.0 22 52 A S H >X5S+ 0 0 0 -4,-5.0 3,-1.7 2,-0.2 4,-1.4 0.981 119.6 43.5 -60.4 -63.5 10.8 46.3 143.1 23 53 A V H 3X5S+ 0 0 0 -4,-2.3 4,-2.8 1,-0.3 3,-0.3 0.913 107.8 62.4 -51.2 -42.5 12.7 47.5 146.2 24 54 A G H 3X< S+ 0 0 8 -4,-2.8 3,-1.9 -5,-0.2 -2,-0.2 0.958 106.9 62.0 -69.9 -51.9 10.3 47.6 151.9 28 58 A N H 3< S+ 0 0 125 -4,-3.5 -2,-0.2 1,-0.3 -1,-0.2 0.868 103.8 49.6 -40.2 -51.3 6.6 48.2 151.7 29 59 A W H 3< S+ 0 0 90 -4,-1.9 2,-4.2 1,-0.3 4,-0.4 0.840 89.0 88.8 -59.2 -29.9 6.0 44.8 153.3 30 60 A G S << S+ 0 0 24 -3,-1.9 -1,-0.3 -4,-0.7 83,-0.2 -0.003 75.6 102.1 -61.4 40.4 8.5 46.1 155.8 31 61 A G S S- 0 0 34 -2,-4.2 -2,-0.1 -3,-0.2 -3,-0.0 -0.235 92.3 -85.0-109.2-161.4 5.5 47.6 157.7 32 62 A S S S+ 0 0 125 1,-0.1 2,-0.2 2,-0.1 -2,-0.1 -0.246 88.2 109.1-103.8 43.1 3.4 46.8 160.7 33 63 A E S S- 0 0 148 -4,-0.4 3,-0.2 3,-0.0 -1,-0.1 -0.457 103.9 -82.8-114.0 55.5 1.0 44.4 158.9 34 64 A N - 0 0 106 -2,-0.2 -2,-0.1 1,-0.1 -5,-0.0 0.938 51.1-126.6 41.5 78.0 2.4 41.2 160.6 35 65 A P + 0 0 66 0, 0.0 -1,-0.1 0, 0.0 -5,-0.1 -0.282 42.4 172.6 -52.4 123.8 5.4 40.5 158.4 36 66 A L > - 0 0 95 -3,-0.2 3,-2.4 -7,-0.0 4,-0.3 -0.758 52.9 -92.6-130.1 175.1 5.1 36.8 157.3 37 67 A P T >> S+ 0 0 99 0, 0.0 3,-0.7 0, 0.0 4,-0.6 0.546 116.1 80.8 -65.8 -2.9 6.8 34.3 154.9 38 68 A V H 3> S+ 0 0 78 1,-0.2 4,-2.3 2,-0.2 5,-0.2 0.766 70.5 77.4 -70.8 -29.0 4.1 35.6 152.5 39 69 A D H <> S+ 0 0 27 -3,-2.4 4,-3.7 1,-0.2 5,-0.3 0.857 88.4 61.2 -47.9 -37.5 6.5 38.6 152.0 40 70 A M H <> S+ 0 0 56 -3,-0.7 4,-3.0 -4,-0.3 5,-0.4 0.966 104.4 42.2 -58.9 -57.7 8.4 36.2 149.8 41 71 A V H X S+ 0 0 68 -4,-0.6 4,-3.5 1,-0.2 5,-0.2 0.952 117.6 49.9 -56.6 -47.6 5.6 35.5 147.2 42 72 A L H X S+ 0 0 80 -4,-2.3 4,-2.8 2,-0.2 -2,-0.2 0.940 115.8 40.1 -55.7 -52.6 4.8 39.2 147.3 43 73 A I H X S+ 0 0 16 -4,-3.7 4,-2.3 2,-0.2 5,-0.3 0.983 116.5 49.6 -60.1 -58.0 8.4 40.3 146.7 44 74 A S H X S+ 0 0 1 -4,-3.0 4,-2.6 -5,-0.3 -2,-0.2 0.910 113.4 48.4 -45.3 -51.0 9.2 37.6 144.2 45 75 A L H X S+ 0 0 82 -4,-3.5 4,-2.8 -5,-0.4 5,-0.3 0.920 106.7 53.9 -60.8 -46.8 6.0 38.5 142.4 46 76 A C H X S+ 0 0 33 -4,-2.8 4,-2.3 -5,-0.2 -1,-0.2 0.917 112.6 43.7 -56.7 -44.1 6.6 42.2 142.2 47 77 A F H X S+ 0 0 3 -4,-2.3 4,-2.5 2,-0.2 5,-0.3 0.960 113.5 51.4 -64.3 -49.4 10.0 41.9 140.7 48 78 A G H X S+ 0 0 3 -4,-2.6 4,-1.4 -5,-0.3 -2,-0.2 0.863 117.0 39.4 -54.8 -41.2 8.8 39.2 138.3 49 79 A L H X S+ 0 0 92 -4,-2.8 4,-2.0 2,-0.2 -1,-0.2 0.756 110.2 59.6 -80.9 -27.6 5.9 41.4 137.2 50 80 A S H X S+ 0 0 4 -4,-2.3 4,-2.9 -5,-0.3 -2,-0.2 0.951 107.8 45.0 -66.9 -46.7 7.9 44.6 137.2 51 81 A I H X S+ 0 0 11 -4,-2.5 4,-3.6 2,-0.2 5,-0.5 0.960 110.0 52.6 -62.3 -52.1 10.4 43.3 134.7 52 82 A A H X S+ 0 0 9 -4,-1.4 4,-2.8 -5,-0.3 -1,-0.2 0.930 112.3 48.4 -49.1 -43.3 7.8 41.8 132.4 53 83 A T H X S+ 0 0 69 -4,-2.0 4,-3.9 1,-0.2 -1,-0.3 0.968 112.6 48.5 -60.5 -50.1 6.2 45.3 132.5 54 84 A M H X>S+ 0 0 10 -4,-2.9 4,-3.1 2,-0.3 5,-0.5 0.851 111.4 46.7 -59.6 -40.9 9.6 46.9 131.8 55 85 A V H X5S+ 0 0 18 -4,-3.6 4,-2.5 2,-0.2 5,-0.4 0.946 115.5 49.2 -67.1 -41.4 10.5 44.7 128.9 56 86 A Q H <5S+ 0 0 131 -4,-2.8 -2,-0.3 -5,-0.5 4,-0.2 0.945 117.1 41.8 -58.0 -45.1 7.0 45.4 127.8 57 87 A C H <5S- 0 0 58 -4,-3.9 -2,-0.2 -5,-0.2 4,-0.2 0.984 140.9 -0.0 -66.6 -60.0 7.6 49.1 128.3 58 88 A F H X>S+ 0 0 36 -4,-3.1 4,-2.2 1,-0.1 5,-0.5 0.188 96.5 109.0-117.1 12.5 11.2 49.6 126.9 59 89 A G H X>S- 0 0 1 1,-0.1 4,-4.5 118,-0.1 5,-0.5 -0.664 75.7-134.4-176.2 118.2 21.2 44.1 133.7 68 98 A P H >5S+ 0 0 2 0, 0.0 4,-2.5 0, 0.0 5,-0.2 0.865 113.2 43.4 -36.8 -56.2 24.9 44.4 133.9 69 99 A A H >5S+ 0 0 0 2,-0.2 4,-3.2 1,-0.2 5,-0.2 0.894 118.6 44.3 -62.9 -40.5 25.2 40.6 133.6 70 100 A V H >5S+ 0 0 7 -3,-0.3 4,-2.0 2,-0.2 -1,-0.2 0.966 115.6 45.9 -69.6 -50.1 22.7 40.5 130.8 71 101 A T H X5S+ 0 0 0 -4,-4.5 4,-1.3 1,-0.2 -2,-0.2 0.837 117.3 49.0 -59.6 -29.8 24.2 43.5 129.0 72 102 A V H X - 0 0 69 -2,-0.6 4,-2.6 -3,-0.1 5,-0.2 0.016 22.7-109.7 -47.2 151.8 29.6 46.7 120.9 82 112 A I H > S+ 0 0 129 1,-0.2 4,-1.0 2,-0.2 -1,-0.1 0.869 119.8 42.4 -49.9 -42.8 32.3 46.9 123.7 83 113 A A H >> S+ 0 0 66 2,-0.2 4,-0.7 1,-0.2 3,-0.5 0.971 113.3 46.6 -73.3 -59.0 31.9 50.6 123.5 84 114 A K H >> S+ 0 0 62 1,-0.2 4,-1.3 2,-0.2 3,-0.6 0.840 108.2 60.1 -55.5 -32.0 28.2 51.1 123.3 85 115 A S H 3X S+ 0 0 12 -4,-2.6 4,-2.2 1,-0.2 5,-0.3 0.901 90.5 65.5 -65.1 -43.0 27.6 48.6 126.1 86 116 A V H X S+ 0 0 12 -4,-0.6 4,-1.6 -3,-0.3 3,-0.7 0.912 106.3 53.9 -70.2 -43.8 12.3 55.8 146.8 104 134 A Y H 3< S+ 0 0 125 -4,-2.5 -2,-0.2 1,-0.3 -1,-0.2 0.887 105.1 56.8 -54.8 -39.5 14.3 56.4 149.9 105 135 A L H 3< S+ 0 0 114 -4,-2.6 -1,-0.3 1,-0.2 -2,-0.2 0.818 103.0 53.5 -62.7 -35.1 12.8 59.9 149.8 106 136 A V H << S+ 0 0 108 -4,-1.1 -2,-0.2 -3,-0.7 -1,-0.2 0.947 122.8 21.0 -68.2 -51.6 9.2 58.6 149.9 107 137 A T >X + 0 0 29 -4,-1.6 3,-1.7 1,-0.1 4,-1.5 -0.389 69.2 152.0-118.7 55.1 9.4 56.3 152.9 108 138 A P T 34 S+ 0 0 68 0, 0.0 4,-0.3 0, 0.0 -1,-0.1 0.729 70.9 58.0 -57.5 -23.6 12.3 57.5 155.0 109 139 A P T 34 S+ 0 0 118 0, 0.0 -2,-0.0 0, 0.0 -3,-0.0 0.438 118.6 25.4 -91.0 6.3 10.8 56.3 158.3 110 140 A S T X4 S+ 0 0 40 -3,-1.7 3,-1.2 2,-0.0 -3,-0.0 0.386 93.4 92.7-139.4 -7.8 10.4 52.6 157.4 111 141 A V G >< + 0 0 18 -4,-1.5 3,-2.6 1,-0.3 4,-0.4 0.813 58.0 95.8 -59.0 -32.4 13.1 52.1 154.7 112 142 A V G 3 + 0 0 131 1,-0.3 -1,-0.3 -4,-0.3 -2,-0.0 0.727 62.0 83.3 -30.6 -35.7 15.6 50.9 157.4 113 143 A G G < S- 0 0 66 -3,-1.2 -1,-0.3 -83,-0.2 4,-0.2 0.591 126.3 -78.8 -50.8 -8.6 14.5 47.4 156.6 114 144 A G < - 0 0 11 -3,-2.6 -2,-0.2 2,-0.1 -1,-0.1 -0.124 34.3-125.5 142.2 -46.4 17.1 47.8 153.8 115 145 A L S S- 0 0 6 -4,-0.4 -92,-0.1 -92,-0.2 -91,-0.1 0.807 95.2 -37.6 70.0 27.9 15.9 49.8 150.8 116 146 A G S S- 0 0 5 -93,-0.2 2,-0.8 -5,-0.2 75,-0.1 0.964 78.3-179.7 83.1 66.5 16.9 46.7 148.8 117 147 A V - 0 0 50 -4,-0.2 2,-1.6 73,-0.1 -1,-0.1 -0.459 4.2-173.7 -95.7 57.8 20.1 45.6 150.6 118 148 A T + 0 0 10 -2,-0.8 2,-0.4 68,-0.1 61,-0.1 -0.329 27.3 148.6 -58.3 87.6 20.9 42.5 148.4 119 149 A T - 0 0 39 -2,-1.6 80,-0.1 83,-0.0 81,-0.1 -0.995 67.2 -83.6-131.8 123.9 23.7 41.3 150.6 120 150 A V + 0 0 24 -2,-0.4 58,-0.2 78,-0.3 59,-0.1 0.114 59.1 174.9 -26.7 87.9 24.7 37.6 151.0 121 151 A H + 0 0 107 54,-0.2 57,-0.2 8,-0.1 56,-0.2 0.997 51.6 76.5 -69.5 -73.9 22.1 37.1 153.7 122 152 A G S S- 0 0 19 54,-1.3 2,-2.4 55,-1.2 55,-0.0 -0.159 94.2-117.8 -42.4 127.4 22.3 33.3 154.4 123 153 A N + 0 0 162 2,-0.0 2,-0.4 6,-0.0 -1,-0.2 -0.434 67.7 132.9 -72.8 72.5 25.5 33.0 156.5 124 154 A L - 0 0 91 -2,-2.4 5,-0.4 53,-0.2 -2,-0.0 -0.983 68.1 -87.2-132.7 125.5 27.4 30.8 154.1 125 155 A T >> - 0 0 94 -2,-0.4 3,-2.5 3,-0.2 4,-1.6 0.103 49.2-104.1 -29.0 116.9 30.9 31.3 152.9 126 156 A A H 3> S+ 0 0 41 1,-0.3 4,-4.6 2,-0.2 5,-0.3 0.571 120.0 56.6 -14.0 -46.5 31.0 33.6 149.9 127 157 A G H 3> S+ 0 0 41 2,-0.2 4,-1.8 1,-0.2 -1,-0.3 0.958 113.8 37.1 -60.7 -51.1 31.6 30.7 147.5 128 158 A H H <> S+ 0 0 116 -3,-2.5 4,-0.9 2,-0.2 -2,-0.2 0.793 121.5 49.5 -69.3 -30.0 28.5 28.9 148.6 129 159 A G H X S+ 0 0 4 -4,-1.6 4,-0.8 -5,-0.4 -2,-0.2 0.931 114.5 42.1 -74.9 -46.0 26.8 32.3 148.9 130 160 A L H X S+ 0 0 41 -4,-4.6 4,-2.4 -5,-0.2 -2,-0.2 0.693 101.9 71.8 -72.1 -25.0 27.9 33.4 145.4 131 161 A L H X S+ 0 0 95 -4,-1.8 4,-2.1 -5,-0.3 5,-0.2 0.964 93.7 52.9 -58.4 -52.4 27.1 30.1 143.9 132 162 A V H X S+ 0 0 19 -4,-0.9 4,-2.0 1,-0.3 -1,-0.2 0.926 112.1 44.8 -49.5 -52.6 23.4 30.6 144.1 133 163 A E H X S+ 0 0 0 -4,-0.8 4,-1.8 1,-0.2 5,-0.4 0.897 108.1 62.0 -59.5 -38.0 23.6 33.9 142.3 134 164 A L H X S+ 0 0 48 -4,-2.4 4,-1.1 1,-0.2 -2,-0.2 0.952 109.3 38.0 -48.6 -62.1 25.9 32.2 139.9 135 165 A I H X S+ 0 0 90 -4,-2.1 4,-2.6 1,-0.2 -1,-0.2 0.830 113.5 54.0 -59.5 -44.2 23.3 29.7 138.7 136 166 A I H X S+ 0 0 0 -4,-2.0 4,-3.6 2,-0.2 5,-0.3 0.920 105.5 49.2 -63.0 -50.1 20.2 32.0 138.7 137 167 A T H X S+ 0 0 0 -4,-1.8 4,-4.6 2,-0.2 5,-0.2 0.903 112.5 55.3 -56.6 -36.7 21.5 34.8 136.5 138 168 A F H X S+ 0 0 45 -4,-1.1 4,-5.7 -5,-0.4 -2,-0.2 0.990 109.5 41.6 -57.1 -66.0 22.4 31.9 134.3 139 169 A Q H X S+ 0 0 47 -4,-2.6 4,-3.3 2,-0.2 -2,-0.2 0.902 120.5 44.6 -51.1 -45.3 18.9 30.5 134.1 140 170 A L H X S+ 0 0 9 -4,-3.6 4,-2.3 2,-0.2 5,-0.2 0.997 116.4 46.7 -59.6 -60.2 17.5 34.0 133.8 141 171 A V H X S+ 0 0 0 -4,-4.6 4,-2.4 -5,-0.3 -2,-0.2 0.914 113.8 49.7 -44.2 -52.0 20.2 34.8 131.3 142 172 A F H X S+ 0 0 48 -4,-5.7 4,-3.8 -5,-0.2 5,-0.3 0.935 106.8 53.5 -57.4 -48.4 19.5 31.5 129.6 143 173 A T H X S+ 0 0 32 -4,-3.3 4,-3.5 -5,-0.2 5,-0.4 0.911 110.2 47.9 -51.6 -47.9 15.7 32.1 129.4 144 174 A I H X S+ 0 0 20 -4,-2.3 4,-2.8 2,-0.2 5,-0.4 0.948 116.0 43.3 -60.7 -50.0 16.2 35.4 127.7 145 175 A F H X S+ 0 0 5 -4,-2.4 4,-3.0 -5,-0.2 -2,-0.2 0.981 117.9 45.7 -59.5 -55.4 18.6 34.0 125.2 146 176 A A H < S+ 0 0 30 -4,-3.8 -2,-0.2 -5,-0.2 -3,-0.2 0.933 120.3 38.2 -51.5 -55.9 16.5 30.9 124.6 147 177 A S H < S+ 0 0 33 -4,-3.5 -1,-0.2 -5,-0.3 -2,-0.2 0.931 125.1 35.7 -64.5 -48.6 13.2 32.7 124.3 148 178 A C H < S+ 0 0 55 -4,-2.8 -3,-0.2 -5,-0.4 -2,-0.2 0.781 87.3 107.2 -81.3 -30.6 14.4 35.8 122.4 149 179 A D S < S- 0 0 26 -4,-3.0 2,-0.1 -5,-0.4 3,-0.0 0.058 77.5 -93.8 -44.6 164.3 17.2 34.4 120.1 150 180 A S S S+ 0 0 85 1,-0.1 -1,-0.1 2,-0.0 -2,-0.0 -0.279 91.1 26.3 -79.2 168.4 16.3 34.2 116.3 151 181 A K S S+ 0 0 165 1,-0.1 2,-0.3 -2,-0.1 -1,-0.1 0.908 71.4 160.1 40.2 101.0 14.9 31.1 114.5 152 182 A R - 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