==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 30-NOV-05 2D80 . COMPND 2 MOLECULE: PHB DEPOLYMERASE; . SOURCE 2 ORGANISM_SCIENTIFIC: PENICILLIUM FUNICULOSUM; . AUTHOR T.HISANO,K.KASUYA,T.SAITO,T.IWATA,K.MIKI . 318 1 4 4 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11140.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 211 66.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 38 11.9 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 18 5.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 27 8.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 14.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 59 18.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 2 0 0 0 0 2 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 1 1 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 21 A T 0 0 130 0, 0.0 191,-2.5 0, 0.0 2,-0.1 0.000 360.0 360.0 360.0 142.3 5.8 61.3 29.0 2 22 A A - 0 0 80 189,-0.2 191,-0.1 1,-0.1 188,-0.1 -0.458 360.0-108.1 -71.6 142.6 2.7 61.0 26.8 3 23 A L - 0 0 3 189,-0.3 -1,-0.1 -2,-0.1 188,-0.1 -0.628 43.1-132.5 -68.4 116.7 3.0 59.8 23.2 4 24 A P - 0 0 49 0, 0.0 2,-0.4 0, 0.0 312,-0.1 -0.154 6.4-119.9 -67.0 161.5 2.4 62.9 21.0 5 25 A A - 0 0 45 310,-0.1 2,-0.3 309,-0.1 308,-0.2 -0.859 35.6-166.6 -96.5 141.7 0.2 63.1 17.9 6 26 A F - 0 0 20 307,-2.8 2,-2.0 -2,-0.4 310,-0.7 -0.845 35.2 -99.0-127.4 163.8 2.0 64.1 14.7 7 27 A N + 0 0 11 207,-0.5 214,-3.0 -2,-0.3 2,-0.4 -0.560 68.9 143.7 -80.2 76.8 1.3 65.3 11.2 8 28 A V E -a 221 0A 0 -2,-2.0 309,-0.3 305,-0.4 214,-0.2 -0.966 54.0-120.4-120.8 133.3 1.6 61.9 9.7 9 29 A N E > - 0 0 34 212,-2.2 3,-2.0 -2,-0.4 214,-0.2 -0.585 15.1-144.4 -73.1 122.6 -0.5 60.5 6.8 10 30 A P E > S+ 0 0 61 0, 0.0 3,-0.6 0, 0.0 27,-0.3 0.693 97.8 63.8 -60.9 -16.5 -2.4 57.4 8.0 11 31 A N E 3 S+ 0 0 97 1,-0.2 -2,-0.1 25,-0.1 211,-0.1 0.348 92.7 64.9 -87.4 7.8 -2.0 56.0 4.5 12 32 A S E < S+ 0 0 16 -3,-2.0 211,-1.3 209,-0.1 2,-0.3 -0.020 72.1 128.6-121.9 29.8 1.8 55.9 4.8 13 33 A V E < +a 223 0A 2 -3,-0.6 25,-1.9 22,-0.3 26,-0.7 -0.702 22.0 154.3 -98.9 138.3 2.4 53.4 7.6 14 34 A S E -ab 224 39A 0 209,-1.9 211,-2.4 -2,-0.3 2,-0.3 -0.926 20.7-150.3-147.9 172.5 4.7 50.3 7.5 15 35 A V E +ab 225 40A 0 24,-1.0 26,-2.4 -2,-0.3 2,-0.3 -0.993 13.0 170.9-147.0 150.1 6.6 48.1 9.9 16 36 A S E +ab 226 41A 0 209,-2.9 211,-3.1 -2,-0.3 2,-0.3 -0.965 6.5 163.7-149.2 168.6 9.7 45.9 10.0 17 37 A G E -ab 227 42A 0 24,-1.0 26,-2.8 -2,-0.3 2,-0.3 -0.983 30.4-107.8-174.9 170.3 11.9 44.0 12.5 18 38 A L E > S- b 0 43A 1 209,-1.7 3,-2.6 -2,-0.3 4,-0.3 -0.803 77.1 -24.8-105.6 147.5 14.5 41.4 13.3 19 39 A S T >> S+ 0 0 10 24,-1.6 4,-2.2 25,-0.3 3,-0.7 -0.228 140.1 2.0 61.9-129.3 14.0 38.0 14.8 20 40 A S H 3> S+ 0 0 1 1,-0.3 4,-2.2 2,-0.2 -1,-0.3 0.776 135.9 59.2 -64.4 -22.6 10.8 37.9 16.9 21 41 A G H <> S+ 0 0 0 -3,-2.6 4,-2.1 2,-0.2 -2,-0.3 0.792 103.2 51.1 -72.8 -29.6 10.4 41.5 15.7 22 42 A G H <> S+ 0 0 0 -3,-0.7 4,-1.9 21,-0.3 -2,-0.2 0.936 109.9 48.6 -67.5 -48.7 10.4 40.1 12.2 23 43 A Y H X S+ 0 0 6 -4,-2.2 4,-2.1 1,-0.2 -2,-0.2 0.930 113.7 47.8 -51.8 -47.7 7.8 37.6 13.1 24 44 A M H X S+ 0 0 0 -4,-2.2 4,-3.0 1,-0.2 5,-0.3 0.871 104.7 58.9 -66.5 -37.8 5.8 40.4 14.7 25 45 A A H X S+ 0 0 0 -4,-2.1 4,-2.8 1,-0.2 -1,-0.2 0.916 110.4 43.6 -55.7 -43.2 6.2 42.7 11.7 26 46 A A H X S+ 0 0 1 -4,-1.9 4,-2.5 2,-0.2 5,-0.3 0.876 111.0 54.1 -70.4 -38.0 4.5 40.0 9.6 27 47 A Q H X S+ 0 0 2 -4,-2.1 4,-2.9 2,-0.2 5,-0.5 0.939 115.0 40.6 -60.9 -45.5 1.8 39.4 12.2 28 48 A L H X S+ 0 0 0 -4,-3.0 4,-2.1 1,-0.2 8,-0.3 0.928 114.3 53.4 -63.9 -47.1 1.0 43.1 12.2 29 49 A G H < S+ 0 0 1 -4,-2.8 -2,-0.2 -5,-0.3 -1,-0.2 0.822 120.4 32.8 -59.8 -32.7 1.4 43.2 8.4 30 50 A V H >< S+ 0 0 1 -4,-2.5 3,-1.2 2,-0.1 53,-0.4 0.930 124.0 40.1 -87.2 -58.7 -1.1 40.4 8.0 31 51 A A H 3< S+ 0 0 0 -4,-2.9 52,-1.9 -5,-0.3 3,-0.2 0.916 131.9 28.1 -60.5 -44.8 -3.5 40.9 10.9 32 52 A Y T >X S+ 0 0 21 -4,-2.1 4,-2.5 -5,-0.5 3,-1.0 -0.315 72.9 142.2-112.3 50.8 -3.6 44.7 10.5 33 53 A S T <4 S+ 0 0 0 -3,-1.2 -1,-0.2 1,-0.3 -2,-0.1 0.737 73.1 59.8 -62.4 -21.5 -2.8 45.0 6.8 34 54 A D T 34 S+ 0 0 89 -3,-0.2 3,-0.3 -4,-0.1 -1,-0.3 0.820 109.8 40.6 -73.0 -32.9 -5.3 47.9 6.8 35 55 A V T <4 S+ 0 0 20 -3,-1.0 2,-1.3 1,-0.3 -22,-0.3 0.891 117.0 46.9 -82.8 -45.2 -3.2 49.8 9.3 36 56 A F S < S+ 0 0 0 -4,-2.5 -1,-0.3 -8,-0.3 -22,-0.1 -0.642 78.4 160.2 -94.9 76.6 0.2 48.9 7.8 37 57 A N + 0 0 42 -2,-1.3 -1,-0.2 -27,-0.3 -23,-0.2 0.391 60.1 52.3 -93.8 -1.2 -1.1 49.8 4.4 38 58 A V S S- 0 0 28 -25,-1.9 54,-2.4 1,-0.4 2,-0.3 0.820 112.8 -98.9 -93.7 -47.4 2.2 50.3 2.5 39 59 A G E -bc 14 92A 0 -26,-0.7 -24,-1.0 52,-0.2 -1,-0.4 -0.979 31.6-103.0 159.6-164.8 3.8 47.0 3.5 40 60 A F E -bc 15 93A 0 52,-1.3 54,-2.7 -2,-0.3 2,-0.4 -0.962 13.0-134.1-150.8 168.5 6.3 45.5 5.9 41 61 A G E -bc 16 94A 0 -26,-2.4 -24,-1.0 -2,-0.3 2,-0.5 -0.984 9.4-162.0-131.4 138.1 9.8 44.1 6.2 42 62 A V E -bc 17 95A 0 52,-3.0 54,-2.3 -2,-0.4 2,-0.7 -0.942 2.3-171.2-124.8 109.5 11.1 40.9 7.8 43 63 A F E S-bc 18 96A 0 -26,-2.8 -24,-1.6 -2,-0.5 -21,-0.3 -0.894 79.1 -25.1 -94.8 113.6 14.7 40.5 8.8 44 64 A A S S+ 0 0 0 52,-3.0 -25,-0.3 -2,-0.7 -22,-0.2 0.922 105.7 123.9 51.4 55.1 15.4 36.9 9.8 45 65 A G - 0 0 0 -3,-0.2 67,-0.2 51,-0.2 -1,-0.1 -0.298 46.0-129.0-119.1-149.8 11.8 36.0 10.9 46 66 A G - 0 0 0 -27,-0.2 -20,-0.1 -2,-0.1 63,-0.1 -0.890 36.0 -37.4-157.3 179.5 9.4 33.4 9.8 47 67 A P > - 0 0 0 0, 0.0 3,-1.9 0, 0.0 4,-0.2 -0.070 62.8-100.1 -48.2 139.2 5.9 32.3 8.6 48 68 A Y T 3 S+ 0 0 1 1,-0.3 26,-0.1 64,-0.1 -24,-0.1 -0.476 112.3 7.0 -55.1 128.2 2.8 34.1 9.8 49 69 A D T > S+ 0 0 0 -2,-0.2 3,-1.3 -26,-0.1 4,-0.5 0.720 87.6 149.1 68.1 23.0 1.3 31.8 12.5 50 70 A a T < + 0 0 2 -3,-1.9 3,-0.5 1,-0.2 4,-0.3 0.894 67.1 42.8 -54.0 -46.3 4.4 29.5 12.4 51 71 A A T 3 S+ 0 0 4 236,-0.6 223,-0.3 -4,-0.2 -1,-0.2 0.265 88.3 89.4 -94.8 12.7 4.4 28.4 16.0 52 72 A R S < S+ 0 0 39 -3,-1.3 -1,-0.2 1,-0.2 -2,-0.1 0.891 105.4 15.4 -77.1 -39.6 0.6 27.8 16.5 53 73 A N S S+ 0 0 98 -3,-0.5 2,-0.3 -4,-0.5 -1,-0.2 0.238 127.0 48.8-124.2 13.3 0.5 24.1 15.5 54 74 A Q S S- 0 0 35 -4,-0.3 220,-0.1 220,-0.1 -1,-0.1 -0.979 96.9 -88.6-145.0 153.0 4.2 23.1 15.5 55 75 A Y > - 0 0 72 -2,-0.3 3,-2.0 1,-0.1 4,-0.3 -0.228 36.0-117.4 -68.3 151.5 6.8 23.7 18.3 56 76 A Y G > S+ 0 0 58 218,-0.3 3,-1.5 1,-0.3 -1,-0.1 0.753 110.3 63.8 -64.6 -26.6 8.7 27.0 18.2 57 77 A T G > S+ 0 0 55 1,-0.3 3,-1.0 2,-0.2 -1,-0.3 0.699 94.9 62.0 -71.6 -17.1 12.1 25.4 17.7 58 78 A S G < S+ 0 0 52 -3,-2.0 -1,-0.3 1,-0.2 -2,-0.2 0.591 100.7 53.9 -79.3 -11.9 10.8 24.1 14.3 59 79 A a G < S+ 0 0 0 -3,-1.5 2,-0.2 -4,-0.3 -1,-0.2 0.061 116.2 43.6-104.2 20.5 10.4 27.7 13.4 60 80 A M S X S+ 0 0 26 -3,-1.0 3,-1.9 1,-0.1 44,-0.3 -0.822 81.8 54.2-145.8-178.0 14.1 28.3 14.3 61 81 A Y T 3 S- 0 0 130 42,-3.0 43,-0.2 1,-0.3 44,-0.2 0.787 122.3 -66.9 53.5 33.9 17.6 27.0 14.0 62 82 A N T 3 S+ 0 0 48 42,-3.0 -1,-0.3 1,-0.1 43,-0.1 0.795 94.9 148.6 57.2 35.5 17.3 26.7 10.3 63 83 A G < - 0 0 20 -3,-1.9 -1,-0.1 41,-0.3 -5,-0.1 -0.179 55.1-104.1 -84.0-175.0 14.7 24.0 10.4 64 84 A Y - 0 0 178 46,-0.1 -5,-0.1 -2,-0.0 44,-0.1 -0.704 36.7-164.5-118.1 80.7 11.8 23.5 7.9 65 85 A P - 0 0 0 0, 0.0 2,-0.2 0, 0.0 -6,-0.1 -0.313 21.6-117.5 -64.7 143.1 8.6 24.7 9.4 66 86 A S - 0 0 52 -16,-0.1 -12,-0.0 1,-0.1 45,-0.0 -0.570 23.7-174.2 -76.0 142.1 5.3 23.6 7.8 67 87 A I > + 0 0 22 -2,-0.2 4,-2.3 2,-0.1 5,-0.3 0.227 57.4 102.5-119.0 11.8 3.1 26.3 6.4 68 88 A T H > S+ 0 0 106 2,-0.2 4,-2.0 1,-0.2 5,-0.1 0.975 92.7 28.7 -57.0 -61.4 0.1 24.1 5.5 69 89 A T H > S+ 0 0 58 2,-0.2 4,-3.2 1,-0.2 5,-0.2 0.903 118.2 57.5 -70.0 -42.2 -2.1 25.1 8.4 70 90 A P H > S+ 0 0 5 0, 0.0 4,-1.6 0, 0.0 -1,-0.2 0.909 111.8 43.1 -55.8 -41.5 -0.6 28.6 8.8 71 91 A T H X S+ 0 0 11 -4,-2.3 4,-2.1 2,-0.2 -2,-0.2 0.918 112.7 52.3 -69.4 -43.9 -1.6 29.3 5.2 72 92 A A H X S+ 0 0 47 -4,-2.0 4,-2.7 -5,-0.3 -1,-0.2 0.897 107.8 52.9 -57.4 -41.9 -5.0 27.7 5.6 73 93 A N H X S+ 0 0 29 -4,-3.2 4,-3.4 2,-0.2 5,-0.2 0.892 105.8 53.0 -63.0 -39.4 -5.6 29.9 8.7 74 94 A M H X S+ 0 0 0 -4,-1.6 4,-1.1 -5,-0.2 11,-0.2 0.945 112.1 45.8 -59.2 -46.8 -4.8 33.0 6.7 75 95 A K H < S+ 0 0 133 -4,-2.1 3,-0.3 1,-0.2 -2,-0.2 0.922 117.6 44.0 -60.1 -45.7 -7.4 32.0 4.1 76 96 A S H < S+ 0 0 88 -4,-2.7 -2,-0.2 1,-0.2 -1,-0.2 0.886 115.8 45.3 -68.5 -41.4 -9.9 31.1 6.8 77 97 A W H ><>S+ 0 0 21 -4,-3.4 3,-2.8 -5,-0.2 5,-1.7 0.578 79.6 129.2 -82.8 -10.1 -9.4 34.1 9.0 78 98 A S B 3<5S+h 82 0B 39 -4,-1.1 6,-0.2 -3,-0.3 5,-0.2 -0.230 81.7 7.7 -52.2 119.5 -9.4 36.6 6.1 79 99 A G T 3 5S+ 0 0 61 3,-2.1 -1,-0.3 1,-0.2 4,-0.2 0.407 133.4 49.8 91.8 -2.7 -11.9 39.4 6.9 80 100 A N T < 5S+ 0 0 115 -3,-2.8 -1,-0.2 2,-0.5 -2,-0.1 0.438 120.8 14.7-126.4 -88.5 -12.6 38.2 10.5 81 101 A Q T 5S+ 0 0 61 -4,-0.3 217,-3.1 -5,-0.1 2,-0.3 0.676 138.2 25.9 -70.3 -17.1 -9.6 37.5 12.8 82 102 A I B - 0 0 49 -6,-0.2 3,-1.7 1,-0.2 4,-0.3 -0.196 40.4-138.8 -48.2 126.3 -8.9 40.8 4.2 85 105 A V G > S+ 0 0 26 1,-0.3 3,-0.8 -11,-0.2 4,-0.5 0.613 98.0 79.9 -66.5 -10.2 -5.9 38.9 2.8 86 106 A A G > S+ 0 0 67 1,-0.2 3,-1.7 2,-0.2 4,-0.3 0.882 81.7 65.4 -59.2 -38.5 -6.8 40.6 -0.5 87 107 A N G X S+ 0 0 45 -3,-1.7 3,-2.0 1,-0.3 -1,-0.2 0.817 89.6 65.4 -49.9 -36.6 -5.0 43.7 1.0 88 108 A L G X S+ 0 0 1 -3,-0.8 3,-1.3 -4,-0.3 -1,-0.3 0.747 88.5 66.1 -66.3 -24.0 -1.7 41.7 0.9 89 109 A G G < S+ 0 0 24 -3,-1.7 32,-0.3 -4,-0.5 -1,-0.3 0.678 103.3 49.0 -68.1 -15.7 -1.8 41.6 -2.8 90 110 A Q G < S+ 0 0 151 -3,-2.0 2,-0.4 -4,-0.3 -1,-0.3 -0.151 95.0 99.3-115.7 35.4 -1.3 45.4 -2.7 91 111 A R < - 0 0 24 -3,-1.3 2,-0.6 2,-0.0 -52,-0.2 -0.967 66.9-132.2-127.4 139.5 1.6 45.5 -0.2 92 112 A K E -c 39 0A 81 -54,-2.4 -52,-1.3 -2,-0.4 2,-0.5 -0.803 29.3-167.3 -84.4 123.8 5.3 45.9 -0.7 93 113 A I E -cd 40 125A 0 31,-2.7 33,-2.3 -2,-0.6 2,-0.4 -0.961 6.0-163.5-121.6 119.9 7.0 43.2 1.4 94 114 A Y E -cd 41 126A 2 -54,-2.7 -52,-3.0 -2,-0.5 2,-0.4 -0.840 9.0-177.0-102.3 138.0 10.8 43.2 2.1 95 115 A M E +cd 42 127A 0 31,-2.9 33,-3.2 -2,-0.4 2,-0.3 -0.991 3.2 175.6-134.9 142.2 12.6 40.1 3.4 96 116 A W E +cd 43 128A 0 -54,-2.3 -52,-3.0 -2,-0.4 2,-0.3 -1.000 5.1 166.4-145.3 143.4 16.3 39.5 4.4 97 117 A T E - d 0 129A 0 31,-2.0 33,-2.2 -2,-0.3 2,-0.3 -0.984 33.7-122.0-144.9 152.9 18.4 36.8 5.8 98 118 A G E > - d 0 130A 0 -2,-0.3 3,-1.3 31,-0.2 33,-0.2 -0.735 26.1-130.6 -81.2 145.2 22.1 36.1 6.3 99 119 A S T 3 S+ 0 0 49 31,-2.4 32,-0.1 -2,-0.3 35,-0.1 0.725 107.7 49.6 -69.8 -17.6 23.2 32.9 4.5 100 120 A S T 3 S+ 0 0 54 33,-2.0 2,-0.5 30,-0.4 35,-0.3 0.163 76.9 130.5-108.0 15.9 24.9 31.8 7.7 101 121 A D < + 0 0 1 -3,-1.3 33,-0.1 33,-0.3 32,-0.1 -0.604 21.6 166.7 -72.2 118.4 22.1 32.5 10.1 102 122 A T + 0 0 101 -2,-0.5 -1,-0.1 3,-0.1 32,-0.1 0.151 66.1 69.8-118.4 16.0 21.5 29.4 12.3 103 123 A T S S- 0 0 39 -42,-0.1 -42,-3.0 -43,-0.1 -2,-0.1 0.829 131.3 -12.8 -97.6 -48.8 19.3 31.1 14.8 104 124 A V S S- 0 0 4 -44,-0.3 -42,-3.0 -43,-0.2 -41,-0.3 0.597 102.8-172.3-109.1 -78.3 16.3 31.5 12.6 105 125 A G > - 0 0 0 -44,-0.2 4,-2.5 -43,-0.1 3,-0.5 -0.014 37.7 -75.9 115.0 158.0 17.7 30.8 9.2 106 126 A P H > S+ 0 0 25 0, 0.0 4,-3.4 0, 0.0 5,-0.2 0.885 123.0 56.6 -54.5 -42.4 17.3 30.7 5.3 107 127 A N H > S+ 0 0 33 2,-0.2 4,-1.0 1,-0.2 -2,-0.1 0.865 110.0 45.1 -61.3 -37.1 15.1 27.6 5.5 108 128 A V H >> S+ 0 0 0 -3,-0.5 4,-1.5 -4,-0.2 3,-0.6 0.957 115.1 46.3 -69.1 -51.6 12.7 29.3 7.8 109 129 A M H 3X S+ 0 0 0 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.871 106.2 60.4 -58.3 -37.8 12.6 32.5 5.8 110 130 A N H 3X S+ 0 0 70 -4,-3.4 4,-2.2 -5,-0.2 -1,-0.2 0.873 103.9 51.3 -56.1 -36.5 12.2 30.4 2.6 111 131 A Q H < S+ 0 0 0 -4,-2.4 3,-2.3 1,-0.3 -2,-0.2 0.964 111.3 45.7 -57.7 -55.2 3.6 31.4 2.4 116 136 A L H >X S+ 0 0 1 -4,-2.8 4,-2.3 1,-0.3 3,-2.0 0.742 98.1 75.4 -61.4 -22.0 3.4 35.0 1.2 117 137 A G T 3< S+ 0 0 50 -4,-1.4 -1,-0.3 1,-0.3 -2,-0.2 0.665 89.7 58.3 -64.2 -15.2 3.6 33.6 -2.3 118 138 A N T <4 S+ 0 0 94 -3,-2.3 -1,-0.3 -4,-0.4 -2,-0.2 0.552 118.9 26.6 -87.3 -8.9 0.0 32.6 -1.9 119 139 A F T <4 S+ 0 0 27 -3,-2.0 2,-0.4 1,-0.3 -2,-0.2 0.536 117.2 46.4-132.1 -15.7 -1.1 36.1 -1.2 120 140 A D S < S- 0 0 5 -4,-2.3 -1,-0.3 -31,-0.1 -31,-0.1 -0.997 81.9-109.9-139.7 133.5 1.2 38.6 -2.9 121 141 A N > - 0 0 110 -2,-0.4 3,-2.9 -32,-0.3 4,-0.3 -0.357 30.2-120.4 -61.6 134.8 2.6 38.7 -6.4 122 142 A S G > S+ 0 0 83 1,-0.3 3,-1.5 2,-0.2 -1,-0.1 0.755 108.5 73.1 -44.9 -31.4 6.4 37.9 -6.5 123 143 A A G 3 S+ 0 0 65 1,-0.3 -1,-0.3 3,-0.0 -2,-0.1 0.776 100.1 43.7 -58.3 -26.9 6.9 41.4 -8.1 124 144 A N G < S+ 0 0 31 -3,-2.9 -31,-2.7 1,-0.1 2,-0.6 0.399 99.9 81.1-102.4 1.7 6.1 43.0 -4.7 125 145 A V E < -d 93 0A 12 -3,-1.5 2,-0.5 -4,-0.3 -31,-0.2 -0.943 57.4-169.6-113.9 116.8 8.2 40.7 -2.5 126 146 A S E -d 94 0A 26 -33,-2.3 -31,-2.9 -2,-0.6 2,-0.5 -0.917 2.0-173.9-104.1 126.2 12.0 41.3 -2.3 127 147 A Y E -d 95 0A 54 -2,-0.5 2,-0.3 -33,-0.2 -31,-0.2 -0.906 8.9-171.3-124.9 100.7 13.9 38.6 -0.6 128 148 A V E -d 96 0A 37 -33,-3.2 -31,-2.0 -2,-0.5 2,-0.5 -0.733 8.4-162.0 -98.5 139.1 17.6 39.5 -0.1 129 149 A T E -d 97 0A 78 -2,-0.3 2,-0.7 -33,-0.2 -31,-0.2 -0.976 5.6-157.1-119.7 121.8 20.4 37.2 1.1 130 150 A T E > -d 98 0A 23 -33,-2.2 -31,-2.4 -2,-0.5 3,-1.4 -0.877 26.9-127.9 -95.1 115.6 23.7 38.5 2.4 131 151 A T T 3 S+ 0 0 125 -2,-0.7 3,-0.1 1,-0.2 -33,-0.0 -0.393 87.2 9.4 -67.9 131.9 26.3 35.8 2.0 132 152 A G T 3 S+ 0 0 35 1,-0.3 -1,-0.2 -2,-0.1 2,-0.2 0.217 91.8 133.5 89.6 -16.1 28.2 34.9 5.2 133 153 A A < - 0 0 0 -3,-1.4 -33,-2.0 -36,-0.1 -32,-0.3 -0.466 41.1-153.3 -73.5 138.6 26.0 37.1 7.5 134 154 A V - 0 0 16 15,-2.1 2,-1.0 -2,-0.2 -33,-0.3 -0.243 48.4 -54.4 -93.5-172.7 24.8 35.5 10.8 135 155 A H S S+ 0 0 10 -35,-0.3 2,-0.3 -2,-0.1 -1,-0.1 -0.567 97.4 106.1 -67.2 104.6 21.7 36.2 12.8 136 156 A T S S- 0 0 0 -2,-1.0 21,-0.2 16,-0.1 20,-0.1 -0.952 78.9 -87.1-172.6 158.8 22.2 40.0 13.3 137 157 A F E -i 157 0C 0 19,-2.2 21,-2.5 -2,-0.3 2,-0.5 -0.712 47.9-128.5 -81.6 125.0 20.8 43.2 12.0 138 158 A P E +i 158 0C 0 0, 0.0 26,-1.3 0, 0.0 27,-0.5 -0.621 40.0 154.8 -81.3 122.2 22.6 44.2 8.8 139 159 A T E -i 159 0C 0 19,-1.7 21,-2.5 -2,-0.5 23,-1.4 -0.812 43.4-130.8-127.4 175.7 24.0 47.7 8.5 140 160 A D S S+ 0 0 43 21,-0.3 2,-0.3 -2,-0.3 19,-0.2 -0.046 81.4 63.2-118.4 31.8 26.9 49.2 6.5 141 161 A F S S- 0 0 46 17,-0.3 2,-1.4 103,-0.2 -2,-0.1 -0.960 87.1-101.9-148.7 166.8 28.6 51.1 9.4 142 162 A N - 0 0 136 -2,-0.3 3,-0.1 17,-0.1 16,-0.0 -0.580 40.6-167.3 -95.3 75.4 30.5 50.4 12.6 143 163 A G > - 0 0 9 -2,-1.4 3,-2.2 101,-0.3 16,-0.1 -0.289 38.7 -88.1 -57.7 144.1 27.9 51.2 15.2 144 164 A A T 3 S+ 0 0 67 1,-0.3 -1,-0.1 99,-0.1 99,-0.1 -0.339 113.5 9.3 -56.8 126.7 29.3 51.5 18.8 145 165 A G T 3 S+ 0 0 47 1,-0.2 -1,-0.3 -3,-0.1 12,-0.1 0.383 89.6 157.6 85.1 -4.7 29.2 48.0 20.4 146 166 A D < - 0 0 34 -3,-2.2 -1,-0.2 9,-0.1 2,-0.2 -0.174 36.6-132.4 -51.0 140.7 28.3 46.2 17.2 147 167 A N - 0 0 14 10,-1.4 12,-0.4 6,-0.2 -4,-0.1 -0.591 37.2 -84.1 -86.1 159.8 29.2 42.5 17.0 148 168 A S > - 0 0 66 -2,-0.2 3,-1.5 10,-0.1 5,-0.2 -0.324 30.6-126.0 -59.4 145.0 30.9 41.1 14.0 149 169 A b T 3 S+ 0 0 19 10,-0.5 -15,-2.1 1,-0.3 -1,-0.1 0.638 113.1 55.6 -67.6 -11.5 28.6 40.1 11.1 150 170 A S T 3 S+ 0 0 86 -17,-0.2 2,-0.4 1,-0.2 -1,-0.3 0.468 103.2 59.0 -98.6 -2.4 30.3 36.7 11.3 151 171 A L S < S- 0 0 105 -3,-1.5 2,-1.1 -17,-0.1 -1,-0.2 -0.950 73.8-144.3-132.9 113.7 29.5 36.1 15.0 152 172 A S + 0 0 40 -2,-0.4 2,-0.3 -3,-0.1 -16,-0.1 -0.631 52.4 119.0 -82.6 101.2 25.9 36.1 16.4 153 173 A T > - 0 0 63 -2,-1.1 3,-2.4 -5,-0.2 4,-0.3 -0.961 57.2 -24.5-154.9 162.5 26.1 37.7 19.8 154 174 A S T 3 S+ 0 0 65 1,-0.3 78,-0.1 -2,-0.3 77,-0.0 -0.210 121.4 25.1 -52.6 142.8 24.7 40.7 21.6 155 175 A P T 3 S- 0 0 6 0, 0.0 -1,-0.3 0, 0.0 3,-0.1 -0.946 84.5-148.3 -85.7 12.1 23.7 43.3 20.5 156 176 A Y < + 0 0 42 -3,-2.4 -19,-2.2 1,-0.2 2,-0.4 0.894 59.3 117.6 57.8 41.6 23.0 41.4 17.3 157 177 A I E +i 137 0C 0 -4,-0.3 -10,-1.4 -21,-0.2 2,-0.3 -0.987 41.0 170.9-135.6 129.1 23.7 44.5 15.2 158 178 A S E -i 138 0C 0 -21,-2.5 -19,-1.7 -2,-0.4 2,-0.9 -0.873 45.5-112.7-136.5 160.2 26.6 44.4 12.7 159 179 A N E +i 139 0C 52 -12,-0.4 -10,-0.5 -2,-0.3 -19,-0.2 -0.884 43.1 160.8 -86.6 100.7 28.4 46.1 9.9 160 180 A b - 0 0 15 -21,-2.5 -20,-0.2 -2,-0.9 -1,-0.1 0.103 61.3-111.2-103.5 17.9 27.6 43.5 7.2 161 181 A N S S+ 0 0 138 -22,-0.5 2,-0.3 1,-0.1 -21,-0.3 0.869 89.9 106.4 47.0 43.0 28.5 46.0 4.5 162 182 A Y - 0 0 50 -23,-1.4 2,-1.9 -21,-0.1 -2,-0.3 -0.926 70.0-138.7-150.7 122.4 24.8 46.1 3.6 163 183 A D > + 0 0 26 -2,-0.3 4,-2.4 1,-0.2 -24,-0.2 -0.571 31.3 170.0 -83.6 80.9 22.3 48.9 4.4 164 184 A G H > S+ 0 0 0 -2,-1.9 4,-2.3 -26,-1.3 -1,-0.2 0.884 73.5 51.7 -62.7 -41.3 19.4 46.7 5.5 165 185 A A H > S+ 0 0 0 -27,-0.5 4,-2.4 80,-0.5 5,-0.2 0.946 112.1 46.5 -60.9 -48.9 17.3 49.6 6.9 166 186 A G H > S+ 0 0 0 1,-0.2 4,-2.5 2,-0.2 5,-0.2 0.899 110.9 52.3 -59.0 -42.8 17.7 51.6 3.6 167 187 A A H X S+ 0 0 25 -4,-2.4 4,-2.4 2,-0.2 5,-0.2 0.943 111.4 46.6 -59.0 -48.9 16.9 48.6 1.5 168 188 A A H X S+ 0 0 0 -4,-2.3 4,-2.4 1,-0.2 5,-0.2 0.922 113.2 47.7 -62.3 -47.1 13.7 47.9 3.4 169 189 A L H X S+ 0 0 0 -4,-2.4 4,-2.9 1,-0.2 5,-0.4 0.899 113.2 48.9 -62.8 -40.8 12.5 51.5 3.4 170 190 A K H X S+ 0 0 98 -4,-2.5 4,-2.0 -5,-0.2 -1,-0.2 0.878 111.9 48.3 -68.0 -36.3 13.2 51.8 -0.4 171 191 A W H < S+ 0 0 83 -4,-2.4 -2,-0.2 -5,-0.2 -1,-0.2 0.924 118.0 41.6 -68.1 -42.1 11.4 48.6 -1.2 172 192 A I H < S+ 0 0 5 -4,-2.4 -2,-0.2 -5,-0.2 -80,-0.2 0.929 131.4 21.7 -69.2 -46.4 8.4 49.6 0.9 173 193 A Y H < S- 0 0 56 -4,-2.9 2,-0.3 1,-0.3 -3,-0.2 0.632 95.1-138.6-102.2 -17.6 8.2 53.3 -0.1 174 194 A G < + 0 0 34 -4,-2.0 -1,-0.3 -5,-0.4 -2,-0.1 -0.681 67.1 24.7 92.1-148.8 10.0 53.5 -3.4 175 195 A S - 0 0 130 -2,-0.3 2,-0.3 -4,-0.1 -4,-0.0 -0.260 69.9-174.0 -59.0 131.7 12.3 56.4 -4.3 176 196 A L - 0 0 34 3,-0.0 3,-0.1 0, 0.0 78,-0.1 -0.953 29.5-105.8-126.5 147.5 13.9 58.1 -1.3 177 197 A N - 0 0 102 -2,-0.3 76,-0.2 76,-0.2 3,-0.1 -0.374 59.8 -80.9 -60.0 147.3 16.1 61.2 -0.9 178 198 A A - 0 0 81 1,-0.1 -1,-0.1 -2,-0.0 3,-0.1 -0.174 56.9 -98.7 -53.0 144.2 19.7 60.2 -0.1 179 199 A R - 0 0 65 1,-0.1 71,-0.2 -3,-0.1 2,-0.2 -0.253 47.7 -85.8 -65.7 154.5 20.2 59.4 3.6 180 200 A N - 0 0 35 69,-2.9 -1,-0.1 1,-0.1 4,-0.1 -0.414 36.0-168.4 -62.7 127.1 21.6 62.0 5.9 181 201 A T + 0 0 143 -2,-0.2 2,-0.2 -3,-0.1 -1,-0.1 0.360 68.8 45.4 -98.7 4.4 25.4 62.0 5.8 182 202 A G S S- 0 0 46 1,-0.2 3,-0.1 67,-0.1 -2,-0.0 -0.462 108.0 -37.0-127.2-160.8 25.8 64.2 8.8 183 203 A T S S- 0 0 132 -2,-0.2 -1,-0.2 1,-0.1 -2,-0.1 -0.346 70.9-101.8 -65.3 144.4 24.4 64.7 12.3 184 204 A L - 0 0 61 1,-0.1 -1,-0.1 -4,-0.1 65,-0.1 -0.314 19.2-143.3 -68.8 151.9 20.7 63.9 12.7 185 205 A S S S+ 0 0 61 -3,-0.1 -1,-0.1 2,-0.1 -2,-0.1 0.599 73.4 56.0 -90.0 -13.2 18.3 66.8 12.8 186 206 A G S S- 0 0 30 25,-0.1 2,-0.3 1,-0.0 23,-0.1 -0.081 73.1-112.2-111.9-160.5 15.9 65.3 15.3 187 207 A S E -E 210 0A 60 23,-1.4 23,-2.4 21,-0.1 2,-0.8 -0.907 22.2-118.3-133.2 163.3 15.5 63.8 18.8 188 208 A V E -E 209 0A 52 -2,-0.3 21,-0.2 21,-0.2 2,-0.1 -0.883 36.8-156.6-103.3 101.1 14.7 60.4 20.2 189 209 A L E -E 208 0A 49 19,-2.4 19,-1.9 -2,-0.8 2,-0.3 -0.462 2.6-149.9 -74.7 145.3 11.5 60.8 22.2 190 210 A S E +E 207 0A 51 17,-0.2 2,-0.3 -2,-0.1 17,-0.2 -0.864 18.6 177.6-107.0 154.2 10.5 58.5 25.0 191 211 A F E -E 206 0A 1 15,-2.1 15,-2.7 -2,-0.3 2,-0.7 -0.975 35.5 -91.9-149.9 160.0 6.9 57.8 25.9 192 212 A A E -E 205 0A 33 -191,-2.5 2,-1.9 -2,-0.3 13,-0.3 -0.655 20.2-154.6 -81.1 115.8 4.9 55.7 28.3 193 213 A Q + 0 0 6 11,-1.4 6,-0.3 -2,-0.7 2,-0.3 -0.600 56.8 126.3 -79.8 74.8 3.9 52.3 27.0 194 214 A S > - 0 0 63 -2,-1.9 3,-2.2 4,-0.2 4,-0.1 -0.881 58.7 -2.6-133.7 159.9 1.0 52.3 29.5 195 215 A G G > S- 0 0 73 -2,-0.3 3,-1.6 1,-0.3 -2,-0.0 -0.353 137.1 -2.9 56.8-128.9 -2.7 51.9 29.2 196 216 A S G 3 S+ 0 0 85 1,-0.3 -1,-0.3 112,-0.1 112,-0.3 0.634 136.5 58.0 -71.0 -13.0 -3.7 51.4 25.5 197 217 A Y G < S+ 0 0 47 -3,-2.2 -1,-0.3 -5,-0.1 2,-0.2 0.436 107.0 55.4 -94.1 -2.6 -0.1 51.9 24.4 198 218 A G < + 0 0 14 -3,-1.6 2,-0.3 -4,-0.1 -4,-0.2 -0.695 56.7 167.6-126.6 177.2 1.2 49.0 26.6 199 219 A A > - 0 0 31 -6,-0.3 3,-1.9 4,-0.3 103,-0.1 -0.976 47.1 -55.5-174.1 166.1 0.7 45.3 27.2 200 220 A N T 3 S+ 0 0 116 -2,-0.3 91,-0.1 1,-0.3 3,-0.1 -0.304 122.5 25.5 -49.9 138.1 1.9 42.1 28.8 201 221 A G T 3 S+ 0 0 10 1,-0.2 63,-1.7 64,-0.1 2,-0.3 0.429 102.5 109.9 82.0 -0.8 5.5 41.4 27.7 202 222 A M B < -J 263 0D 15 -3,-1.9 61,-0.3 61,-0.3 -1,-0.2 -0.848 69.0-117.6-113.4 146.3 6.2 45.1 26.9 203 223 A D - 0 0 24 59,-2.0 -4,-0.3 -2,-0.3 59,-0.2 -0.162 27.2-117.8 -66.7 169.3 8.4 47.6 28.7 204 224 A T S S+ 0 0 92 -6,-0.1 -11,-1.4 -12,-0.1 2,-0.4 0.484 96.5 55.3 -90.8 -0.9 6.8 50.7 30.3 205 225 A T E -E 192 0A 45 -13,-0.3 2,-0.3 -12,-0.1 -13,-0.2 -0.997 61.3-178.9-132.2 134.4 8.7 53.0 28.0 206 226 A G E -E 191 0A 0 -15,-2.7 -15,-2.1 -2,-0.4 2,-0.3 -0.757 12.8-146.2-117.7 174.0 8.9 53.2 24.2 207 227 A Y E -EF 190 260A 41 53,-1.8 53,-3.2 -2,-0.3 2,-0.3 -0.913 10.4-170.7-135.4 162.3 10.9 55.5 21.9 208 228 A L E -EF 189 259A 0 -19,-1.9 -19,-2.4 -2,-0.3 2,-0.5 -0.954 21.5-132.5-150.8 139.4 10.6 57.1 18.5 209 229 A Y E -EF 188 258A 2 49,-2.7 49,-2.2 -2,-0.3 -21,-0.2 -0.814 25.7-170.7 -89.1 128.7 13.0 59.0 16.3 210 230 A V E -E 187 0A 3 -23,-2.4 -23,-1.4 -2,-0.5 47,-0.1 -0.944 14.4-139.8-127.0 108.6 11.4 62.2 15.1 211 231 A P >> - 0 0 0 0, 0.0 4,-1.5 0, 0.0 3,-1.3 -0.261 28.8-110.8 -62.0 155.0 13.2 64.3 12.4 212 232 A Q H 3> S+ 0 0 131 1,-0.3 4,-1.3 2,-0.2 3,-0.1 0.857 119.1 58.8 -54.0 -36.1 13.0 68.1 12.8 213 233 A S H 34 S+ 0 0 23 39,-0.2 6,-0.5 1,-0.2 4,-0.3 0.799 109.4 42.6 -66.3 -27.3 10.8 68.3 9.7 214 234 A c H <4 S+ 0 0 3 -3,-1.3 -207,-0.5 1,-0.1 3,-0.3 0.685 107.1 61.4 -91.1 -20.4 8.2 66.0 11.4 215 235 A A H < S+ 0 0 66 -4,-1.5 -2,-0.2 1,-0.2 -1,-0.1 0.855 95.6 60.3 -73.4 -35.1 8.4 67.7 14.8 216 236 A S S < S- 0 0 78 -4,-1.3 -1,-0.2 1,-0.1 -2,-0.1 0.727 94.1-137.1 -70.3 -24.4 7.2 71.1 13.6 217 237 A G S S+ 0 0 31 -4,-0.3 -1,-0.1 -3,-0.3 -3,-0.1 0.368 81.3 103.0 81.5 -5.8 3.9 69.8 12.4 218 238 A A S S+ 0 0 89 -5,-0.2 2,-0.4 1,-0.1 -4,-0.1 0.551 74.4 58.6 -86.0 -7.3 4.3 72.0 9.2 219 239 A T S S- 0 0 49 -6,-0.5 2,-0.5 -5,-0.1 -2,-0.2 -0.981 82.5-124.7-129.7 131.3 5.2 68.9 7.1 220 240 A V - 0 0 70 -2,-0.4 -212,-0.2 -212,-0.1 2,-0.2 -0.616 38.3-171.5 -75.1 120.3 3.3 65.7 6.4 221 241 A c E -a 8 0A 6 -214,-3.0 -212,-2.2 -2,-0.5 35,-0.2 -0.544 17.6-129.5-108.3 170.8 5.4 62.7 7.4 222 242 A S E - g 0 256A 14 33,-2.2 35,-2.6 -214,-0.2 2,-0.4 -0.662 21.3-129.1-110.2 173.1 5.2 59.0 7.1 223 243 A L E -ag 13 257A 0 -211,-1.3 -209,-1.9 -214,-0.2 2,-0.5 -0.984 19.5-178.8-133.0 126.0 5.6 56.4 9.8 224 244 A H E -ag 14 258A 0 33,-2.7 35,-2.2 -2,-0.4 2,-0.6 -0.990 16.0-150.6-119.1 128.6 7.8 53.3 10.0 225 245 A V E -ag 15 259A 0 -211,-2.4 -209,-2.9 -2,-0.5 2,-0.6 -0.859 10.7-162.8 -96.9 123.3 7.6 51.0 13.0 226 246 A A E -a 16 0A 1 33,-2.9 2,-0.6 -2,-0.6 -209,-0.2 -0.930 3.6-158.0-112.6 119.7 10.9 49.2 13.7 227 247 A L E -a 17 0A 0 -211,-3.1 -209,-1.7 -2,-0.6 -206,-0.1 -0.845 10.3-137.8-104.9 117.5 10.8 46.2 16.0 228 248 A H - 0 0 2 -2,-0.6 57,-0.2 33,-0.5 5,-0.1 -0.148 24.2-123.2 -60.4 162.7 13.9 45.0 17.9 229 249 A G > - 0 0 0 1,-0.2 3,-1.6 -209,-0.2 -210,-0.2 -0.242 45.6 -53.0 -96.8-170.7 14.5 41.2 18.1 230 250 A d T 3 S+ 0 0 28 1,-0.3 -1,-0.2 2,-0.2 53,-0.2 -0.349 128.7 16.6 -61.0 147.6 14.9 38.9 20.9 231 251 A L T 3 S+ 0 0 56 51,-3.1 -1,-0.3 1,-0.1 52,-0.1 0.660 108.5 93.2 59.1 17.7 17.7 40.0 23.4 232 252 A Q < + 0 0 2 -3,-1.6 9,-0.2 50,-0.3 -2,-0.2 0.284 49.0 119.7-121.1 8.4 17.4 43.4 21.8 233 253 A S S >> S- 0 0 0 49,-0.4 4,-2.3 -4,-0.1 3,-1.1 -0.245 81.9-102.0 -65.9 165.1 14.9 45.2 24.0 234 254 A Y H 3> S+ 0 0 93 29,-0.3 4,-2.4 1,-0.3 6,-0.1 0.881 123.3 62.1 -54.4 -39.1 16.1 48.4 25.8 235 255 A S H 34 S+ 0 0 73 28,-0.4 -1,-0.3 1,-0.2 29,-0.1 0.840 112.2 35.8 -56.0 -34.9 16.4 46.2 28.9 236 256 A S H <4 S+ 0 0 52 -3,-1.1 -2,-0.2 2,-0.1 -1,-0.2 0.876 138.4 8.3 -88.7 -43.3 19.1 44.1 27.2 237 257 A I H >< S- 0 0 16 -4,-2.3 3,-1.7 1,-0.3 -3,-0.2 0.183 85.9-141.5-131.3 15.9 21.1 46.5 25.0 238 258 A G T 3< S- 0 0 25 -4,-2.4 3,-0.4 -5,-0.3 -1,-0.3 -0.312 72.2 -18.2 59.3-134.0 19.9 50.0 25.9 239 259 A S T 3> S+ 0 0 59 1,-0.2 4,-2.6 2,-0.1 5,-0.3 0.291 102.9 109.2 -92.2 10.8 19.6 52.4 23.0 240 260 A R H <> S+ 0 0 93 -3,-1.7 4,-2.6 1,-0.2 -1,-0.2 0.830 79.6 45.5 -63.5 -34.7 21.8 50.3 20.6 241 261 A F H > S+ 0 0 5 -3,-0.4 4,-1.0 -9,-0.2 -1,-0.2 0.936 114.5 49.2 -71.2 -45.5 18.9 49.2 18.3 242 262 A I H 4 S+ 0 0 3 -4,-0.3 6,-0.3 1,-0.2 -2,-0.2 0.894 124.6 30.1 -54.4 -43.2 17.5 52.7 18.2 243 263 A Q H < S+ 0 0 82 -4,-2.6 3,-0.2 1,-0.1 -2,-0.2 0.788 122.3 42.2 -91.1 -31.9 20.9 54.2 17.4 244 264 A N H < S+ 0 0 16 -4,-2.6 -101,-0.3 -5,-0.3 -103,-0.2 0.381 90.2 78.2-108.0 2.7 22.8 51.6 15.4 245 265 A T S < S- 0 0 0 -4,-1.0 -80,-0.5 -5,-0.1 -1,-0.2 0.644 91.4-125.3 -92.9 -16.6 20.4 50.0 13.0 246 266 A G S > S+ 0 0 4 -3,-0.2 4,-0.6 -4,-0.2 3,-0.1 0.482 75.0 116.7 92.2 3.7 20.5 52.8 10.4 247 267 A Y H >> + 0 0 0 1,-0.2 4,-2.4 2,-0.1 3,-0.7 0.890 69.9 62.1 -65.2 -39.7 16.8 53.7 10.0 248 268 A N H 3> S+ 0 0 6 -6,-0.3 4,-2.6 1,-0.3 -1,-0.2 0.846 95.1 56.1 -64.0 -38.4 17.2 57.2 11.4 249 269 A K H 34 S+ 0 0 48 1,-0.2 -69,-2.9 2,-0.2 4,-0.5 0.818 113.6 43.2 -67.2 -27.7 19.6 58.6 8.8 250 270 A W H X< S+ 0 0 17 -3,-0.7 3,-0.8 -4,-0.6 4,-0.5 0.889 112.9 51.1 -77.2 -44.1 17.0 57.6 6.1 251 271 A A H ><>S+ 0 0 0 -4,-2.4 5,-1.6 1,-0.2 3,-1.4 0.897 102.8 63.6 -55.0 -39.6 14.0 58.9 8.1 252 272 A D T 3<5S+ 0 0 15 -4,-2.6 -39,-0.2 1,-0.3 -1,-0.2 0.732 110.0 34.1 -65.9 -27.9 15.8 62.2 8.6 253 273 A T T < 5S+ 0 0 43 -3,-0.8 -1,-0.3 -4,-0.5 -76,-0.2 0.328 117.7 55.5-105.4 6.2 15.9 63.2 4.9 254 274 A N T < 5S- 0 0 19 -3,-1.4 -32,-0.2 -4,-0.5 -2,-0.2 0.071 106.8-109.1-132.1 26.1 12.6 61.7 4.0 255 275 A N T 5S+ 0 0 60 -3,-0.2 -33,-2.2 -4,-0.2 2,-0.4 0.910 71.3 142.7 48.7 53.0 10.0 63.2 6.4 256 276 A M E < - g 0 222A 2 -5,-1.6 2,-0.4 -35,-0.2 -33,-0.2 -0.981 44.2-149.7-129.2 132.3 9.6 59.9 8.2 257 277 A I E - g 0 223A 0 -35,-2.6 -33,-2.7 -2,-0.4 2,-0.6 -0.830 13.2-150.9 -91.5 139.7 9.1 59.1 11.9 258 278 A I E -Fg 209 224A 0 -49,-2.2 -49,-2.7 -2,-0.4 2,-0.4 -0.950 8.7-156.5-111.4 113.4 10.6 55.8 13.2 259 279 A L E -Fg 208 225A 0 -35,-2.2 -33,-2.9 -2,-0.6 -51,-0.3 -0.756 4.9-166.0 -89.7 131.7 8.7 54.3 16.1 260 280 A Y E -F 207 0A 1 -53,-3.2 -53,-1.8 -2,-0.4 -33,-0.1 -0.734 5.5-167.6-119.7 81.8 10.6 51.9 18.3 261 281 A P - 0 0 0 0, 0.0 -33,-0.5 0, 0.0 2,-0.5 -0.311 16.1-137.9 -64.9 153.1 8.2 49.9 20.6 262 282 A Q - 0 0 5 -59,-0.2 -59,-2.0 -35,-0.1 2,-0.1 -0.965 15.4-166.2-124.2 126.2 10.0 48.0 23.4 263 283 A A B -J 202 0D 0 -2,-0.5 -28,-0.4 -61,-0.3 -29,-0.3 -0.257 17.7-142.2 -84.6-174.8 9.4 44.5 24.8 264 284 A I - 0 0 52 -63,-1.7 19,-0.3 20,-0.3 20,-0.1 -0.994 23.7 -92.3-154.1 145.6 10.9 43.4 28.1 265 285 A P - 0 0 22 0, 0.0 2,-0.4 0, 0.0 17,-0.1 -0.344 41.4-167.8 -58.7 140.1 12.4 40.1 29.5 266 286 A D E -K 280 0E 26 14,-2.6 14,-2.8 1,-0.1 16,-0.2 -0.905 16.7-177.6-140.8 103.2 9.6 38.1 31.2 267 287 A Y E + 0 0 170 -2,-0.4 2,-0.3 12,-0.2 12,-0.1 0.389 50.8 110.6 -89.6 4.3 10.6 35.2 33.4 268 288 A T E S- 0 0 85 12,-0.1 12,-0.4 1,-0.0 2,-0.4 -0.632 71.4-123.6 -77.2 134.4 7.1 34.2 34.1 269 289 A I E - 0 0 110 -2,-0.3 2,-0.3 10,-0.2 10,-0.3 -0.645 34.5-176.4 -79.8 132.2 6.1 30.9 32.5 270 290 A H E -K 278 0E 46 8,-2.3 8,-2.9 -2,-0.4 2,-0.3 -0.905 32.4-103.2-127.5 154.7 3.0 31.1 30.3 271 291 A A E -K 277 0E 76 -2,-0.3 21,-0.3 6,-0.2 6,-0.3 -0.596 44.2-164.2 -69.9 135.3 0.9 28.6 28.3 272 292 A I - 0 0 20 4,-2.4 4,-0.4 -2,-0.3 17,-0.2 -0.741 33.8 -96.0-119.1 172.4 1.7 28.9 24.6 273 293 A W S S+ 0 0 44 15,-2.3 2,-0.4 -2,-0.2 16,-0.1 0.873 103.7 16.4 -52.0 -43.3 -0.0 27.8 21.4 274 294 A N S S+ 0 0 47 14,-0.4 -218,-0.3 -223,-0.3 -1,-0.2 -0.991 115.4 24.0-142.3 137.0 2.0 24.6 21.1 275 295 A G S S- 0 0 51 -2,-0.4 2,-0.7 -220,-0.1 -1,-0.1 0.596 102.9 -88.6 89.7 11.1 4.2 22.4 23.3 276 296 A G S S- 0 0 46 -4,-0.4 -4,-2.4 -3,-0.1 2,-0.3 -0.797 82.0 -6.3 103.4-113.0 2.9 23.4 26.7 277 297 A V E +K 271 0E 87 -2,-0.7 2,-0.3 -6,-0.3 -6,-0.2 -0.908 53.3 171.1-131.3 156.6 4.4 26.3 28.6 278 298 A L E -K 270 0E 37 -8,-2.9 -8,-2.3 -2,-0.3 2,-0.1 -0.966 22.5-137.5-163.1 138.6 7.3 28.7 28.2 279 299 A S E - 0 0 34 -2,-0.3 -12,-0.2 -10,-0.3 -10,-0.2 -0.414 20.4-130.4 -87.4 176.2 8.7 31.9 29.7 280 300 A N E > +K 266 0E 1 -14,-2.8 -14,-2.6 -12,-0.4 3,-1.5 -0.498 41.7 154.9-128.4 60.0 10.0 34.8 27.7 281 301 A P T 3 + 0 0 46 0, 0.0 -14,-0.1 0, 0.0 -1,-0.1 0.744 69.9 58.8 -59.1 -26.0 13.4 35.5 29.3 282 302 A N T 3 S- 0 0 70 -16,-0.2 -51,-3.1 -3,-0.1 -49,-0.4 0.484 107.6-119.5 -89.7 -1.8 14.9 37.0 26.1 283 303 A G < + 0 0 0 -3,-1.5 -51,-0.2 -19,-0.3 -20,-0.2 0.890 52.2 168.2 67.3 38.8 12.3 39.8 25.8 284 304 A d - 0 0 7 -54,-0.1 -20,-0.3 1,-0.1 -1,-0.2 -0.414 41.7-101.9 -74.8 158.4 11.0 38.6 22.4 285 305 A W - 0 0 0 -57,-0.2 2,-1.1 -2,-0.1 -1,-0.1 -0.474 52.6 -89.9 -71.3 154.8 7.9 39.9 20.8 286 306 A D S S+ 0 0 3 1,-0.2 17,-0.1 -2,-0.1 -1,-0.1 -0.569 70.5 137.0 -82.1 99.5 5.0 37.4 21.1 287 307 A W S S+ 0 0 14 -2,-1.1 -236,-0.6 9,-0.0 -1,-0.2 0.220 73.0 52.9-116.3 10.5 5.0 35.1 18.2 288 308 A V S S- 0 0 2 -3,-0.1 -15,-2.3 -238,-0.1 -14,-0.4 0.491 116.0 -99.4-123.3 -9.5 4.3 31.9 20.2 289 309 A G > + 0 0 4 -17,-0.2 3,-1.2 -16,-0.1 5,-0.1 0.692 67.8 146.9 99.0 22.5 1.2 32.9 22.2 290 310 A W T 3 S+ 0 0 19 1,-0.2 -19,-0.2 -18,-0.1 3,-0.1 0.877 82.1 31.4 -52.0 -41.3 2.7 33.9 25.5 291 311 A Y T 3 S- 0 0 22 1,-0.3 10,-0.4 -91,-0.1 -1,-0.2 0.023 129.9 -15.7-116.3 25.8 0.1 36.5 26.1 292 312 A G X - 0 0 23 -3,-1.2 3,-1.2 -21,-0.3 -1,-0.3 -0.578 54.0-109.7 150.5 149.9 -2.9 35.2 24.3 293 313 A S T 3 S+ 0 0 88 1,-0.3 3,-0.3 -2,-0.2 -1,-0.1 0.712 120.1 55.5 -66.7 -20.4 -4.4 32.7 21.8 294 314 A N T > + 0 0 47 1,-0.2 3,-2.0 -3,-0.1 6,-0.6 0.028 67.6 127.5-102.0 24.3 -4.9 35.7 19.6 295 315 A A T < S+ 0 0 5 -3,-1.2 8,-0.3 1,-0.3 -1,-0.2 0.844 84.0 31.4 -55.8 -39.3 -1.3 36.9 19.6 296 316 A D T 3 S+ 0 0 0 -3,-0.3 -1,-0.3 -4,-0.1 2,-0.2 0.183 113.1 79.8-104.0 17.3 -1.1 37.0 15.8 297 317 A Q S X S- 0 0 24 -3,-2.0 3,-2.3 1,-0.1 -215,-0.2 -0.706 99.6 -72.6-114.7 168.3 -4.8 37.9 15.3 298 318 A I T 3 S+ 0 0 73 -217,-3.1 3,-0.1 1,-0.3 -1,-0.1 -0.427 124.1 31.4 -58.3 130.0 -6.7 41.2 15.6 299 319 A G T 3 S+ 0 0 35 1,-0.4 -1,-0.3 -2,-0.1 -4,-0.1 0.106 77.0 148.0 102.9 -22.3 -6.9 41.9 19.3 300 320 A G <> - 0 0 0 -3,-2.3 4,-3.2 -6,-0.6 -1,-0.4 -0.237 54.5-125.9 -43.8 132.5 -3.6 40.3 20.2 301 321 A V H > S+ 0 0 52 -10,-0.4 4,-1.5 1,-0.2 -1,-0.1 0.843 103.6 43.0 -66.1 -36.3 -2.5 42.4 23.1 302 322 A Q H > S+ 0 0 4 2,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.912 117.3 46.6 -75.0 -41.5 1.0 43.4 21.8 303 323 A M H > S+ 0 0 0 -8,-0.3 4,-3.1 1,-0.2 5,-0.3 0.919 111.3 53.0 -62.4 -42.6 -0.3 44.1 18.3 304 324 A A H X S+ 0 0 41 -4,-3.2 4,-1.8 1,-0.2 -1,-0.2 0.878 110.0 48.6 -59.4 -38.2 -3.2 46.1 19.8 305 325 A A H X S+ 0 0 2 -4,-1.5 4,-2.1 -5,-0.2 -1,-0.2 0.918 112.7 46.2 -68.6 -45.4 -0.7 48.2 21.8 306 326 A I H X S+ 0 0 0 -4,-2.4 4,-2.5 2,-0.2 -2,-0.2 0.931 112.9 49.8 -64.7 -45.0 1.5 48.9 18.8 307 327 A V H X S+ 0 0 5 -4,-3.1 4,-2.7 1,-0.2 -1,-0.2 0.865 108.3 55.3 -60.1 -35.1 -1.5 49.7 16.6 308 328 A G H X S+ 0 0 15 -4,-1.8 4,-2.0 -112,-0.3 -2,-0.2 0.917 107.4 48.2 -61.8 -42.9 -2.6 52.0 19.4 309 329 A Q H X S+ 0 0 0 -4,-2.1 4,-2.4 2,-0.2 -2,-0.2 0.918 112.0 50.2 -62.3 -44.1 0.7 53.8 19.3 310 330 A V H X S+ 0 0 2 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.930 109.3 50.3 -59.9 -48.1 0.4 54.1 15.5 311 331 A K H X S+ 0 0 130 -4,-2.7 4,-0.6 1,-0.2 -1,-0.2 0.870 110.9 49.9 -61.2 -37.2 -3.2 55.5 15.7 312 332 A Q H >< S+ 0 0 54 -4,-2.0 3,-0.8 2,-0.2 4,-0.3 0.946 111.1 48.7 -64.2 -48.4 -2.0 58.1 18.3 313 333 A I H >< S+ 0 0 0 -4,-2.4 -307,-2.8 1,-0.2 3,-1.0 0.925 115.6 42.7 -59.4 -45.7 0.9 59.2 16.1 314 334 A V H >< S+ 0 0 23 -4,-2.6 3,-1.4 1,-0.2 -1,-0.2 0.514 92.1 85.3 -81.2 -4.0 -1.2 59.5 13.0 315 335 A S T << S+ 0 0 73 -3,-0.8 -1,-0.2 -4,-0.6 -2,-0.2 0.658 81.1 64.7 -70.7 -13.4 -4.1 61.2 14.8 316 336 A G T < S+ 0 0 18 -3,-1.0 -1,-0.3 -310,-0.7 -2,-0.1 0.312 70.9 142.7 -91.6 9.6 -2.3 64.5 14.3 317 337 A F < 0 0 88 -3,-1.4 -310,-0.1 -309,-0.3 -308,-0.1 -0.253 360.0 360.0 -56.1 130.8 -2.6 64.4 10.6 318 338 A Q 0 0 183 -101,-0.1 -1,-0.1 -99,-0.0 -100,-0.0 -0.303 360.0 360.0 -95.7 360.0 -3.3 67.9 9.2