==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER SIGNALING PROTEIN/CYTOKINE 12-DEC-05 2D9Q . COMPND 2 MOLECULE: CSF3; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR T.TAMADA,R.KUROKI . 467 3 9 9 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 24598.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 282 60.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 6 1.3 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 97 20.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 37 7.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 7.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 92 19.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 1 1 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 1 4 6 1 1 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 7 A S 0 0 89 0, 0.0 4,-0.2 0, 0.0 164,-0.0 0.000 360.0 360.0 360.0 158.5 -62.2 51.9 25.9 2 8 A S + 0 0 79 2,-0.1 0, 0.0 3,-0.0 0, 0.0 0.487 360.0 83.1 -58.2 -12.3 -58.9 50.9 24.1 3 9 A L S S- 0 0 10 162,-0.1 5,-0.0 3,-0.0 2,-0.0 -0.914 93.2-120.1 -98.9 113.0 -60.0 47.3 24.9 4 10 A P > - 0 0 55 0, 0.0 4,-1.5 0, 0.0 5,-0.2 -0.300 13.6-125.7 -51.3 126.8 -62.4 46.1 22.2 5 11 A Q H >> S+ 0 0 120 -4,-0.2 4,-1.9 1,-0.2 3,-1.2 0.945 110.1 53.9 -34.5 -58.2 -65.7 45.1 23.5 6 12 A S H >> S+ 0 0 50 1,-0.3 4,-2.9 2,-0.2 3,-0.7 0.921 104.6 53.9 -51.2 -54.3 -65.3 41.7 21.8 7 13 A F H 34 S+ 0 0 9 1,-0.3 4,-0.5 2,-0.2 -1,-0.3 0.759 109.1 49.0 -48.6 -35.1 -61.9 40.9 23.4 8 14 A L H S+ 0 0 0 -4,-0.5 4,-1.2 -5,-0.3 -2,-0.2 0.796 107.0 49.7 -86.2 -26.0 -62.2 36.9 28.2 12 18 A L H X S+ 0 0 15 -4,-1.0 4,-2.4 2,-0.2 5,-0.3 0.857 106.3 55.4 -82.5 -38.7 -65.1 36.5 30.3 13 19 A E H X S+ 0 0 2 -4,-2.0 4,-2.5 1,-0.2 -2,-0.2 0.966 108.2 49.5 -52.0 -55.0 -66.4 33.5 28.5 14 20 A Q H X S+ 0 0 5 -4,-1.4 4,-3.3 2,-0.2 5,-0.3 0.840 109.2 52.6 -59.9 -35.3 -63.1 31.8 29.1 15 21 A V H X S+ 0 0 0 -4,-1.2 4,-2.9 2,-0.2 -2,-0.2 0.988 108.6 47.0 -61.9 -64.8 -63.2 32.7 32.7 16 22 A R H X S+ 0 0 39 -4,-2.4 4,-2.0 1,-0.2 -2,-0.2 0.824 115.7 51.7 -42.1 -37.2 -66.7 31.2 33.3 17 23 A K H X S+ 0 0 48 -4,-2.5 4,-2.6 -5,-0.3 -1,-0.2 0.991 109.4 43.5 -69.9 -58.8 -65.4 28.2 31.3 18 24 A I H X S+ 0 0 0 -4,-3.3 4,-2.7 2,-0.2 -1,-0.2 0.798 108.9 62.1 -51.5 -31.4 -62.2 27.6 33.3 19 25 A Q H X S+ 0 0 55 -4,-2.9 4,-2.9 -5,-0.3 5,-0.2 0.995 106.3 44.7 -61.0 -54.1 -64.2 28.2 36.5 20 26 A G H X S+ 0 0 40 -4,-2.0 4,-3.3 1,-0.2 -2,-0.2 0.950 110.3 55.3 -44.7 -61.2 -66.3 25.2 35.6 21 27 A D H X S+ 0 0 14 -4,-2.6 4,-2.0 2,-0.2 5,-0.3 0.934 109.9 45.5 -39.0 -63.0 -63.2 23.3 34.7 22 28 A G H X S+ 0 0 1 -4,-2.7 4,-2.7 1,-0.2 3,-0.2 0.968 113.2 51.3 -44.0 -63.9 -61.7 24.0 38.2 23 29 A A H X S+ 0 0 44 -4,-2.9 4,-2.9 1,-0.2 5,-0.3 0.857 105.9 52.7 -49.3 -47.6 -65.0 23.0 39.8 24 30 A A H X S+ 0 0 40 -4,-3.3 4,-2.0 -5,-0.2 -1,-0.2 0.986 114.2 44.1 -49.9 -58.0 -65.3 19.8 38.0 25 31 A L H < S+ 0 0 1 -4,-2.0 -2,-0.2 -3,-0.2 5,-0.2 0.859 113.7 50.6 -49.7 -45.8 -61.7 18.8 39.1 26 32 A Q H >X S+ 0 0 54 -4,-2.7 4,-1.7 -5,-0.3 3,-1.4 0.995 113.1 44.0 -65.3 -54.4 -62.4 20.0 42.6 27 33 A E H 3X S+ 0 0 124 -4,-2.9 4,-1.0 1,-0.3 -1,-0.2 0.767 110.9 56.5 -62.2 -21.7 -65.6 18.0 42.9 28 34 A K H 3< S+ 0 0 91 -4,-2.0 -1,-0.3 -5,-0.3 -2,-0.2 0.055 108.1 47.3 -96.1 25.3 -63.8 15.0 41.3 29 35 A L H <> S+ 0 0 0 -3,-1.4 6,-0.9 -5,-0.1 4,-0.9 0.444 106.0 57.6-127.3 -48.3 -61.1 14.9 44.0 30 36 A a H < S+ 0 0 39 -4,-1.7 4,-0.5 4,-0.3 -2,-0.2 0.793 115.1 37.2 -47.0 -38.7 -63.5 15.3 46.6 31 37 A A T < S+ 0 0 58 -4,-1.0 -1,-0.2 -5,-0.2 -3,-0.2 0.879 118.8 47.7 -91.9 -28.0 -65.2 12.1 45.4 32 38 A T T 4 S+ 0 0 38 1,-0.2 -2,-0.2 -5,-0.1 -1,-0.2 0.365 134.7 6.8 -88.7 8.4 -62.1 10.3 44.4 33 39 A Y S < S- 0 0 57 -4,-0.9 -3,-0.2 -3,-0.2 -1,-0.2 0.279 94.3-115.7-160.1 0.1 -59.9 10.8 47.5 34 40 A K + 0 0 164 -4,-0.5 2,-0.9 -5,-0.4 -4,-0.3 0.766 67.1 141.8 53.6 37.7 -62.3 12.6 50.0 35 41 A L + 0 0 26 -6,-0.9 -1,-0.2 1,-0.1 -5,-0.1 -0.688 11.2 143.5-100.6 76.6 -60.1 15.7 49.9 36 42 A a + 0 0 51 -2,-0.9 -1,-0.1 -6,-0.2 -6,-0.1 0.448 50.1 61.0-100.6 -2.3 -62.7 18.4 50.0 37 43 A H - 0 0 107 -3,-0.1 3,-0.3 1,-0.1 -1,-0.1 -0.995 56.0-162.3-140.1 111.8 -61.4 21.2 52.1 38 44 A P S S+ 0 0 28 0, 0.0 3,-0.2 0, 0.0 -1,-0.1 0.326 84.4 79.7 -79.4 0.9 -58.2 23.0 51.1 39 45 A E S > S+ 0 0 124 1,-0.2 3,-2.7 2,-0.1 4,-0.3 0.965 86.6 58.3 -59.0 -60.9 -57.9 24.2 54.6 40 46 A E T 3 S+ 0 0 144 1,-0.3 4,-0.3 -3,-0.3 -1,-0.2 0.593 104.9 52.3 -50.2 -5.8 -56.5 20.9 55.6 41 47 A L T 3> S+ 0 0 8 -3,-0.2 4,-2.8 1,-0.2 -1,-0.3 0.320 72.6 105.1-118.6 16.1 -53.8 21.2 53.2 42 48 A V H <> S+ 0 0 80 -3,-2.7 4,-1.9 1,-0.3 5,-0.2 0.900 85.0 45.9 -66.7 -41.1 -52.4 24.6 54.1 43 49 A L H > S+ 0 0 139 -4,-0.3 4,-3.7 1,-0.3 -1,-0.3 0.937 109.6 52.9 -65.6 -51.3 -49.4 23.2 55.7 44 50 A L H > S+ 0 0 32 -4,-0.3 4,-0.7 1,-0.2 -1,-0.3 0.911 104.6 63.0 -49.6 -44.0 -48.8 20.8 52.9 45 51 A G H >X>S+ 0 0 7 -4,-2.8 4,-1.6 1,-0.2 3,-1.6 0.936 109.8 33.5 -44.4 -66.9 -49.0 24.0 50.8 46 52 A H H 3<5S+ 0 0 154 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.926 105.8 74.2 -59.9 -42.8 -46.0 25.7 52.3 47 53 A S H 3<5S+ 0 0 75 -4,-3.7 -1,-0.3 1,-0.3 -2,-0.2 0.705 112.9 26.8 -44.8 -18.6 -44.4 22.3 52.7 48 54 A L H <<5S- 0 0 34 -3,-1.6 -1,-0.3 -4,-0.7 85,-0.3 0.614 107.1-124.8-116.9 -27.9 -43.9 22.5 49.0 49 55 A G T <5 - 0 0 43 -4,-1.6 -3,-0.2 -5,-0.2 -4,-0.1 0.983 25.9-163.8 75.6 74.0 -43.8 26.2 48.4 50 56 A I < - 0 0 11 -5,-0.5 2,-0.7 81,-0.1 -1,-0.2 -0.747 14.9-138.9 -94.4 102.9 -46.4 26.8 45.8 51 57 A P - 0 0 57 0, 0.0 2,-0.3 0, 0.0 31,-0.1 -0.402 23.8-157.4 -62.4 108.0 -45.8 30.2 44.4 52 58 A W - 0 0 76 -2,-0.7 23,-0.0 1,-0.0 95,-0.0 -0.643 17.7-106.7 -85.3 148.5 -49.3 31.6 44.1 53 59 A A - 0 0 17 -2,-0.3 2,-0.2 22,-0.1 101,-0.1 -0.565 25.9-150.0 -83.4 142.7 -50.2 34.3 41.7 54 60 A P - 0 0 84 0, 0.0 21,-0.2 0, 0.0 3,-0.1 -0.459 12.4-177.2 -92.0 161.0 -50.8 37.8 42.8 55 61 A L + 0 0 21 -2,-0.2 3,-0.2 20,-0.1 -2,-0.0 -0.126 39.0 116.6-161.1 64.2 -53.2 40.2 41.0 56 62 A S + 0 0 94 2,-0.2 4,-0.2 1,-0.1 5,-0.1 0.128 51.9 88.9-124.8 19.0 -53.4 43.6 42.4 57 63 A S S S+ 0 0 38 11,-0.1 -1,-0.1 2,-0.1 12,-0.1 0.521 104.3 29.1 -87.7 -8.6 -52.0 45.8 39.5 58 64 A b S S+ 0 0 20 -3,-0.2 4,-0.4 10,-0.1 3,-0.3 0.834 79.8 99.9-112.2 -50.6 -55.5 46.0 38.2 59 65 A P S S- 0 0 65 0, 0.0 -2,-0.1 0, 0.0 -3,-0.1 0.503 123.2 -50.4 -24.7 -46.4 -58.3 45.8 40.9 60 66 A S S S+ 0 0 87 -4,-0.2 -2,-0.1 101,-0.0 -3,-0.1 0.215 86.2 146.7-174.4 27.9 -58.5 49.7 40.6 61 67 A Q S S- 0 0 138 -3,-0.3 2,-0.3 -5,-0.1 -3,-0.1 0.472 82.3 -59.8 -53.0 -11.7 -54.7 51.0 40.9 62 68 A A - 0 0 63 -4,-0.4 3,-0.0 0, 0.0 -5,-0.0 -0.950 68.0 -71.6 169.7-144.3 -55.7 53.8 38.6 63 69 A L S S+ 0 0 169 -2,-0.3 2,-0.4 105,-0.0 -5,-0.1 -0.323 90.8 111.8-136.3 48.2 -57.0 53.7 35.1 64 70 A Q - 0 0 156 1,-0.1 -3,-0.1 -6,-0.1 0, 0.0 -0.951 43.5-175.8-116.9 115.9 -53.7 52.6 33.2 65 71 A L > + 0 0 34 -2,-0.4 3,-2.7 2,-0.1 5,-0.2 0.993 49.5 71.5 -62.2-107.2 -53.9 48.9 31.7 66 72 A A T 3 S+ 0 0 31 1,-0.3 55,-0.1 2,-0.2 -2,-0.0 0.197 97.2 46.5 -18.4 159.9 -51.0 47.1 30.0 67 73 A G T 3> S+ 0 0 49 53,-0.2 4,-1.0 1,-0.1 -1,-0.3 -0.053 115.1 59.8 68.0 -31.0 -48.5 46.1 32.7 68 74 A b H <> S+ 0 0 7 -3,-2.7 4,-2.3 2,-0.2 -2,-0.2 0.904 103.1 42.6 -81.5 -60.6 -51.8 45.0 34.2 69 75 A L H > S+ 0 0 5 1,-0.2 4,-1.3 2,-0.2 5,-0.3 0.888 111.7 64.8 -46.9 -38.2 -52.9 42.5 31.5 70 76 A S H > S+ 0 0 36 -5,-0.2 4,-2.4 1,-0.2 -1,-0.2 0.954 103.5 39.1 -51.0 -58.4 -49.3 41.8 31.9 71 77 A Q H X S+ 0 0 43 -4,-1.0 4,-2.6 2,-0.2 -2,-0.2 0.955 116.4 52.5 -56.5 -61.0 -49.7 40.6 35.5 72 78 A L H >X S+ 0 0 4 -4,-2.3 3,-1.5 1,-0.2 4,-1.3 0.914 110.1 46.6 -28.4 -98.7 -52.9 38.8 34.7 73 79 A H H 3X S+ 0 0 5 -4,-1.3 4,-3.1 1,-0.2 -1,-0.2 0.710 109.5 55.8 -11.2 -60.1 -51.4 37.0 31.9 74 80 A S H 3X S+ 0 0 59 -4,-2.4 4,-2.5 -5,-0.3 -1,-0.2 0.907 108.4 48.5 -57.2 -48.2 -48.3 36.0 34.0 75 81 A G H X S+ 0 0 36 -4,-2.5 3,-1.7 -3,-0.2 4,-1.5 0.990 110.8 45.7 -61.1 -60.3 -47.9 30.5 36.2 79 85 A Y H >X S+ 0 0 3 -4,-2.7 4,-3.8 1,-0.3 3,-0.6 0.895 107.5 60.4 -49.1 -40.7 -50.9 28.3 37.1 80 86 A Q H 3X S+ 0 0 41 -4,-2.6 4,-1.0 -5,-0.4 -1,-0.3 0.836 107.2 46.2 -58.5 -32.8 -50.5 26.7 33.6 81 87 A G H S+ 0 0 2 -4,-3.8 5,-0.6 1,-0.2 3,-0.4 0.839 111.8 51.0 -63.2 -32.9 -51.1 22.3 36.5 84 90 A Q H ><5S+ 0 0 128 -4,-1.0 3,-2.4 -5,-0.3 -1,-0.2 0.939 108.4 50.5 -62.3 -50.7 -48.4 21.0 34.1 85 91 A A T 3<5S+ 0 0 9 -4,-1.5 -1,-0.2 1,-0.3 -2,-0.2 0.526 93.7 75.2 -73.2 -0.4 -46.3 20.1 37.0 86 92 A L T > 5S- 0 0 1 -4,-0.5 3,-1.5 -3,-0.4 -1,-0.3 0.652 94.5-144.3 -79.9 -17.3 -49.3 18.4 38.6 87 93 A E T < 5 - 0 0 119 -3,-2.4 -3,-0.1 1,-0.3 7,-0.1 0.911 57.3 -62.4 53.2 49.7 -48.6 15.6 36.0 88 94 A G T 3 > S- 0 0 18 -2,-2.1 4,-1.9 50,-0.1 3,-1.7 -0.959 75.3 -98.9-151.0 146.2 -53.8 10.1 38.5 91 97 A P T 34 S+ 0 0 128 0, 0.0 -2,-0.0 0, 0.0 -1,-0.0 0.788 117.8 57.0 -33.9 -44.8 -55.4 8.3 35.6 92 98 A E T 34 S+ 0 0 135 2,-0.1 4,-0.2 1,-0.1 -3,-0.1 0.735 119.4 32.6 -72.1 -16.9 -59.0 8.8 36.7 93 99 A L T X> S+ 0 0 0 -3,-1.7 3,-1.7 -5,-0.3 4,-1.0 0.880 87.8 94.2 -98.3 -68.3 -58.4 12.5 36.7 94 100 A G H 3X S+ 0 0 17 -4,-1.9 4,-1.6 -6,-1.5 -2,-0.1 0.408 88.4 50.7 17.6 -61.0 -55.9 13.3 34.0 95 101 A P H 3> S+ 0 0 81 0, 0.0 4,-2.0 0, 0.0 -1,-0.3 0.978 112.4 45.5 -65.7 -54.3 -58.7 14.1 31.5 96 102 A T H <> S+ 0 0 29 -3,-1.7 4,-1.3 1,-0.3 -2,-0.2 0.891 117.4 46.0 -48.7 -41.6 -60.6 16.5 33.8 97 103 A L H X S+ 0 0 0 -4,-1.0 4,-2.5 1,-0.2 -1,-0.3 0.890 109.4 56.0 -73.1 -32.6 -57.3 18.0 34.6 98 104 A D H X S+ 0 0 73 -4,-1.6 4,-1.6 -5,-0.3 -2,-0.2 0.782 100.5 54.7 -76.2 -27.9 -56.3 18.2 31.0 99 105 A T H X S+ 0 0 53 -4,-2.0 4,-2.5 2,-0.2 5,-0.2 0.966 111.9 46.2 -66.0 -47.6 -59.3 20.1 29.8 100 106 A L H X S+ 0 0 0 -4,-1.3 4,-2.9 1,-0.3 5,-0.4 0.934 109.3 55.4 -55.4 -49.0 -58.5 22.9 32.4 101 107 A Q H X S+ 0 0 30 -4,-2.5 4,-1.6 1,-0.2 -1,-0.3 0.911 112.6 42.6 -52.6 -44.9 -54.9 22.8 31.5 102 108 A L H X S+ 0 0 42 -4,-1.6 4,-0.9 2,-0.2 -1,-0.2 0.866 115.1 46.6 -68.7 -41.5 -55.8 23.4 28.0 103 109 A D H >X S+ 0 0 6 -4,-2.5 4,-1.6 2,-0.2 3,-0.6 0.882 110.1 51.9 -69.8 -46.5 -58.4 26.1 28.5 104 110 A V H >X S+ 0 0 0 -4,-2.9 4,-2.4 1,-0.2 3,-0.6 0.948 107.2 57.8 -52.8 -44.7 -56.3 28.0 30.9 105 111 A A H 3X S+ 0 0 18 -4,-1.6 4,-1.7 -5,-0.4 -1,-0.2 0.793 105.4 48.8 -50.3 -35.2 -53.7 27.9 28.2 106 112 A D H X S+ 0 0 1 -4,-2.4 4,-1.8 -5,-0.3 3,-0.6 0.932 111.9 34.5 -59.7 -51.0 -53.4 32.7 28.7 109 115 A T H 3X S+ 0 0 44 -4,-1.7 4,-2.1 1,-0.2 5,-0.3 0.762 105.9 70.3 -84.0 -9.9 -52.7 33.4 25.0 110 116 A T H 3X S+ 0 0 8 -4,-1.5 4,-0.8 2,-0.2 -1,-0.2 0.778 108.1 39.5 -67.8 -16.4 -55.9 35.2 24.4 111 117 A I H X S+ 0 0 40 -4,-2.1 4,-2.5 2,-0.2 3,-1.6 0.996 108.1 52.2 -70.0 -63.3 -52.0 38.4 21.8 114 120 A Q H 3< S+ 0 0 10 -4,-0.8 -2,-0.2 -5,-0.3 -1,-0.2 0.817 109.9 55.1 -32.3 -36.9 -54.3 41.3 22.7 115 121 A M H >< S+ 0 0 2 -4,-2.2 6,-1.2 1,-0.2 3,-0.9 0.876 108.3 44.5 -71.2 -38.7 -51.1 42.6 24.4 116 122 A E H X< S+ 0 0 94 -3,-1.6 3,-2.3 -4,-1.6 -2,-0.2 0.910 106.5 62.1 -68.4 -38.5 -49.1 42.3 21.2 117 123 A E T 3< S+ 0 0 140 -4,-2.5 -1,-0.2 1,-0.3 -2,-0.2 0.246 112.1 38.7 -71.0 11.1 -52.0 44.0 19.3 118 124 A L T < S- 0 0 67 -3,-0.9 -1,-0.3 -5,-0.3 -2,-0.2 0.170 113.5-118.2-138.3 7.4 -51.4 47.0 21.6 119 125 A G S < S+ 0 0 62 -3,-2.3 -3,-0.2 1,-0.1 -4,-0.1 0.064 86.9 107.7 82.7 -24.5 -47.6 46.8 21.6 120 126 A M + 0 0 79 -5,-0.5 -4,-0.2 -2,-0.1 -53,-0.2 0.455 50.6 103.9 -69.9 -4.7 -47.3 46.2 25.4 121 127 A A S S- 0 0 11 -6,-1.2 4,-0.1 -8,-0.1 -2,-0.0 -0.751 83.0-117.7 -77.5 116.6 -46.3 42.7 24.9 122 128 A P - 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