==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=8-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 30-MAY-08 3DAZ . COMPND 2 MOLECULE: CARBONIC ANHYDRASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.GENIS,K.H.SIPPEL,N.CASE,L.GOVINDASAMY,M.AGBANDJE-MCKENNA, . 257 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11873.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 165 64.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 57 22.2 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 23 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 14.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 2 1 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A H 0 0 204 0, 0.0 2,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 162.6 10.0 -0.0 8.9 2 5 A W + 0 0 33 1,-0.1 2,-0.2 2,-0.1 7,-0.2 -0.366 360.0 132.9 -75.8 157.5 7.8 -1.8 11.4 3 6 A G - 0 0 7 5,-2.6 10,-0.1 2,-0.1 -1,-0.1 -0.761 63.3 -82.8-166.4-144.9 5.4 -4.6 10.4 4 7 A Y S S+ 0 0 33 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.171 82.8 107.8-129.8 15.7 4.4 -8.1 11.5 5 8 A G S >> S- 0 0 37 1,-0.1 4,-1.0 4,-0.1 3,-0.6 -0.222 85.7 -92.9 -87.7-175.4 7.1 -10.2 10.0 6 9 A K T 34 S+ 0 0 172 1,-0.2 3,-0.1 2,-0.2 -1,-0.1 0.868 121.9 42.7 -73.1 -26.5 9.9 -12.0 11.9 7 10 A H T 34 S+ 0 0 153 1,-0.2 -1,-0.2 -5,-0.0 -3,-0.0 0.662 129.2 23.4 -94.5 -3.3 12.4 -9.2 11.6 8 11 A N T <4 S+ 0 0 54 -3,-0.6 -5,-2.6 -6,-0.0 -2,-0.2 0.199 92.0 124.0-145.1 19.2 10.2 -6.2 12.2 9 12 A G S >X S- 0 0 4 -4,-1.0 3,-3.1 -5,-0.2 4,-0.6 0.062 79.3 -66.9 -82.4-176.3 7.3 -7.5 14.2 10 13 A P G >4 S+ 0 0 27 0, 0.0 3,-0.9 0, 0.0 4,-0.5 0.767 126.6 61.2 -48.4 -32.0 5.9 -6.5 17.6 11 14 A E G 34 S+ 0 0 136 1,-0.3 3,-0.0 2,-0.1 -5,-0.0 0.632 107.5 46.9 -77.5 -5.4 8.8 -7.6 19.6 12 15 A H G X4 S+ 0 0 65 -3,-3.1 3,-1.8 1,-0.1 4,-0.5 0.538 86.1 89.9-100.8 -15.4 11.0 -5.2 17.7 13 16 A W G XX S+ 0 0 4 -3,-0.9 4,-2.8 -4,-0.6 3,-1.3 0.803 73.4 69.0 -59.2 -34.7 8.7 -2.1 18.0 14 17 A H G 34 S+ 0 0 67 -4,-0.5 -1,-0.3 1,-0.3 7,-0.1 0.735 87.6 66.6 -62.3 -19.8 10.2 -0.8 21.2 15 18 A K G <4 S+ 0 0 134 -3,-1.8 -1,-0.3 1,-0.2 -2,-0.2 0.878 118.7 22.9 -69.6 -32.5 13.5 0.0 19.5 16 19 A D T <4 S+ 0 0 123 -3,-1.3 -2,-0.2 -4,-0.5 -1,-0.2 0.738 136.5 35.8 -99.0 -24.3 11.7 2.7 17.4 17 20 A F >< - 0 0 55 -4,-2.8 3,-2.5 1,-0.1 -1,-0.2 -0.785 64.4-179.4-130.4 82.5 8.7 3.3 19.8 18 21 A P G > S+ 0 0 102 0, 0.0 3,-2.0 0, 0.0 -4,-0.1 0.739 75.6 76.3 -64.8 -18.9 9.9 3.0 23.3 19 22 A I G > S+ 0 0 50 1,-0.3 3,-2.0 179,-0.1 -5,-0.1 0.674 72.0 87.9 -62.4 -13.8 6.4 3.6 24.7 20 23 A A G < S+ 0 0 7 -3,-2.5 -1,-0.3 1,-0.3 -6,-0.1 0.764 89.2 48.2 -50.2 -27.6 5.8 -0.0 23.5 21 24 A K G < S+ 0 0 151 -3,-2.0 -1,-0.3 -4,-0.1 -2,-0.1 -0.183 94.1 130.4-107.0 37.2 7.1 -0.8 27.0 22 25 A G S < S- 0 0 16 -3,-2.0 3,-0.5 1,-0.1 -3,-0.0 -0.204 70.3-105.7 -86.4 178.6 4.7 1.7 28.6 23 26 A E S S+ 0 0 112 1,-0.2 226,-0.2 -2,-0.1 -1,-0.1 0.462 111.4 37.9 -86.7 -9.1 2.3 1.4 31.6 24 27 A R S S+ 0 0 50 224,-0.1 -1,-0.2 168,-0.1 2,-0.1 -0.170 79.4 152.5-143.0 52.4 -1.0 1.4 29.6 25 28 A Q - 0 0 3 -3,-0.5 220,-0.1 221,-0.3 170,-0.1 -0.448 34.0-100.8 -82.5 151.4 -0.3 -0.6 26.5 26 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.1 -2,-0.1 -0.869 76.5 40.9-122.5 160.0 -2.9 -2.6 24.5 27 30 A P + 0 0 0 0, 0.0 218,-2.6 0, 0.0 2,-0.3 0.622 64.7 176.0 -83.6-175.9 -4.2 -5.2 23.8 28 31 A V - 0 0 1 216,-0.3 77,-1.3 -2,-0.2 2,-0.4 -0.917 36.0 -98.9-140.9 166.2 -4.6 -7.2 27.0 29 32 A D E -a 105 0A 35 216,-0.4 2,-0.9 -2,-0.3 77,-0.2 -0.765 33.9-138.2 -83.9 133.0 -6.1 -10.4 28.2 30 33 A I E -a 106 0A 0 75,-2.9 77,-2.8 -2,-0.4 2,-0.8 -0.826 11.2-159.4 -94.7 108.0 -9.5 -10.0 29.7 31 34 A D >> - 0 0 59 -2,-0.9 4,-1.1 75,-0.2 3,-0.8 -0.801 4.3-160.3 -84.2 113.0 -9.7 -12.2 32.8 32 35 A T T 34 S+ 0 0 47 -2,-0.8 -1,-0.2 1,-0.3 222,-0.0 0.711 85.0 55.5 -73.4 -21.0 -13.5 -12.4 33.2 33 36 A H T 34 S+ 0 0 166 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.695 112.6 40.4 -84.4 -21.2 -13.3 -13.5 36.8 34 37 A T T <4 S+ 0 0 96 -3,-0.8 -2,-0.2 2,-0.1 218,-0.2 0.455 86.9 108.1-107.5 -4.4 -11.2 -10.5 38.0 35 38 A A S < S- 0 0 18 -4,-1.1 2,-0.6 216,-0.1 218,-0.2 -0.511 71.0-126.2 -66.8 142.7 -13.0 -7.8 35.9 36 39 A K E -c 253 0B 132 216,-2.4 218,-2.6 -2,-0.1 2,-0.2 -0.817 8.5-131.1 -98.5 121.4 -15.1 -5.6 38.2 37 40 A Y E -c 254 0B 90 -2,-0.6 218,-0.2 216,-0.2 220,-0.1 -0.512 25.1-166.7 -61.2 128.4 -18.7 -5.1 37.6 38 41 A D > - 0 0 30 216,-2.8 3,-2.4 -2,-0.2 -1,-0.1 -0.851 15.3-172.8-125.7 102.3 -19.3 -1.3 37.8 39 42 A P T 3 S+ 0 0 96 0, 0.0 -1,-0.1 0, 0.0 216,-0.1 0.595 82.3 74.2 -73.4 -1.3 -22.9 -0.3 38.0 40 43 A S T 3 S+ 0 0 82 2,-0.1 2,-0.2 -3,-0.0 215,-0.1 0.677 77.0 102.9 -75.8 -15.0 -21.8 3.3 37.6 41 44 A L < - 0 0 28 -3,-2.4 3,-0.1 213,-0.2 38,-0.1 -0.419 66.4-141.8 -73.9 135.7 -21.2 2.5 34.0 42 45 A K - 0 0 134 37,-0.9 39,-0.1 -2,-0.2 -1,-0.1 -0.524 25.7 -91.8 -91.7 163.2 -23.8 3.7 31.5 43 46 A P - 0 0 103 0, 0.0 36,-1.8 0, 0.0 2,-0.2 -0.413 48.8-103.2 -61.3 149.7 -25.1 1.9 28.4 44 47 A L E -D 78 0B 16 141,-0.3 2,-0.5 34,-0.3 34,-0.2 -0.473 26.8-148.5 -66.2 144.8 -23.3 2.7 25.3 45 48 A S E -D 77 0B 43 32,-2.7 32,-2.0 -2,-0.2 2,-0.6 -0.933 15.8-176.8-119.8 104.6 -25.0 5.1 22.8 46 49 A V E -D 76 0B 35 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.879 3.8-179.3-103.1 119.9 -24.1 4.3 19.2 47 50 A S E +D 75 0B 43 28,-2.7 28,-2.0 -2,-0.6 3,-0.2 -0.792 24.4 141.4-121.9 90.4 -25.6 6.8 16.8 48 51 A Y > + 0 0 3 -2,-0.6 3,-1.7 26,-0.2 130,-0.2 0.191 34.0 106.2-113.0 9.2 -24.6 5.7 13.3 49 52 A D T 3 S+ 0 0 74 1,-0.3 -1,-0.1 -3,-0.1 25,-0.1 0.873 86.2 43.6 -66.2 -27.9 -27.7 6.3 11.3 50 53 A Q T 3 S+ 0 0 120 23,-0.7 -1,-0.3 -3,-0.2 24,-0.2 0.269 84.1 142.6 -98.1 18.4 -26.2 9.4 9.6 51 54 A A < - 0 0 23 -3,-1.7 2,-0.5 22,-0.2 123,-0.1 -0.175 34.9-159.0 -58.8 142.1 -22.8 7.8 8.9 52 55 A T - 0 0 48 16,-0.3 16,-2.8 122,-0.1 2,-0.2 -0.857 2.7-161.6-125.2 103.5 -21.1 8.6 5.6 53 56 A S E +E 67 0B 1 -2,-0.5 121,-0.5 122,-0.4 14,-0.3 -0.505 12.1 175.4 -75.9 149.3 -18.4 6.2 4.4 54 57 A L E - 0 0 80 12,-3.2 118,-2.5 1,-0.4 2,-0.3 0.712 51.0 -7.0-114.0 -48.2 -16.0 7.6 1.8 55 58 A R E -EF 66 171B 85 11,-1.1 11,-2.5 116,-0.3 2,-0.4 -0.969 45.3-135.4-154.6 155.5 -13.2 5.2 0.9 56 59 A I E -EF 65 170B 0 114,-2.6 114,-2.2 -2,-0.3 2,-0.4 -0.993 29.2-172.4-123.6 137.4 -11.5 1.8 1.6 57 60 A L E -EF 64 169B 30 7,-2.3 7,-2.7 -2,-0.4 2,-0.8 -0.989 26.9-144.8-133.8 135.5 -7.7 1.8 1.7 58 61 A N E -E 63 0B 0 110,-2.8 109,-2.7 -2,-0.4 5,-0.2 -0.870 22.3-178.8 -89.1 108.5 -5.0 -0.9 1.9 59 62 A N - 0 0 57 3,-1.9 4,-0.1 -2,-0.8 -1,-0.1 0.299 52.2-100.0 -96.6 13.6 -2.4 0.9 4.0 60 63 A G S S+ 0 0 5 2,-0.4 106,-0.1 166,-0.2 3,-0.1 0.225 117.9 53.3 91.7 -13.1 0.1 -2.0 4.0 61 64 A H S S- 0 0 46 1,-0.5 2,-0.3 -58,-0.1 166,-0.1 0.575 123.7 -26.2-123.1 -25.3 -0.9 -3.2 7.6 62 65 A A S S- 0 0 6 -5,-0.1 -3,-1.9 165,-0.1 -1,-0.5 -0.917 70.5 -92.0-166.0-177.6 -4.7 -3.6 7.3 63 66 A F E -E 58 0B 0 29,-0.3 29,-0.5 -2,-0.3 2,-0.4 -0.965 38.1-158.7-112.4 143.6 -7.5 -2.3 5.3 64 67 A N E -EG 57 91B 16 -7,-2.7 -7,-2.3 -2,-0.4 2,-0.6 -0.954 13.0-149.8-117.2 138.4 -9.4 0.7 6.6 65 68 A V E -EG 56 90B 0 25,-2.8 25,-1.9 -2,-0.4 2,-0.3 -0.943 26.8-151.1 -99.8 125.1 -12.9 2.0 5.8 66 69 A E E -EG 55 89B 49 -11,-2.5 -12,-3.2 -2,-0.6 -11,-1.1 -0.739 9.6-161.3-102.7 145.8 -12.9 5.8 6.2 67 70 A F E -E 53 0B 6 21,-2.5 2,-0.6 -2,-0.3 -14,-0.2 -0.839 31.4 -99.7-120.7 155.0 -15.8 8.0 7.2 68 71 A D + 0 0 41 -16,-2.8 -16,-0.3 -2,-0.3 5,-0.3 -0.652 42.3 170.5 -71.1 115.7 -16.5 11.7 6.9 69 72 A D + 0 0 42 -2,-0.6 -1,-0.1 1,-0.1 17,-0.1 -0.012 44.4 106.3-116.9 27.4 -15.8 13.0 10.4 70 73 A S S S+ 0 0 80 56,-0.0 2,-0.3 2,-0.0 -1,-0.1 0.467 89.6 23.4 -86.6 1.4 -16.0 16.8 9.7 71 74 A Q S S- 0 0 120 -3,-0.2 2,-2.2 3,-0.1 3,-0.4 -0.943 100.0 -84.0-153.6 165.0 -19.4 16.8 11.5 72 75 A D S S+ 0 0 89 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.393 76.5 128.7 -73.3 60.8 -21.2 14.9 14.2 73 76 A K S S+ 0 0 49 -2,-2.2 -23,-0.7 1,-0.3 2,-0.5 0.943 75.3 19.6 -74.7 -59.7 -22.7 12.3 11.7 74 77 A A S S+ 0 0 6 -3,-0.4 13,-2.7 -6,-0.3 2,-0.3 -0.976 84.3 168.1-120.2 107.5 -21.7 9.0 13.4 75 78 A V E -DH 47 86B 12 -28,-2.0 -28,-2.7 -2,-0.5 2,-0.4 -0.874 30.0-146.9-132.0 160.7 -20.9 9.3 17.1 76 79 A L E +DH 46 85B 0 9,-2.5 9,-2.4 -2,-0.3 2,-0.3 -0.977 29.5 156.0-121.5 131.4 -20.3 7.3 20.2 77 80 A K E +D 45 0B 75 -32,-2.0 -32,-2.7 -2,-0.4 7,-0.1 -0.892 37.9 36.1-143.2 174.9 -21.3 8.6 23.6 78 81 A G E > S+D 44 0B 24 5,-0.3 3,-2.3 -2,-0.3 -34,-0.3 -0.418 70.7 88.3 78.5-155.7 -22.2 7.1 27.0 79 82 A G T 3 S- 0 0 5 -36,-1.8 -37,-0.9 1,-0.3 -1,-0.1 -0.431 119.7 -30.2 56.1-136.8 -20.5 4.0 28.5 80 83 A P T 3 S+ 0 0 41 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.216 115.2 111.9 -90.8 8.5 -17.4 5.3 30.4 81 84 A L < - 0 0 12 -3,-2.3 2,-0.4 -39,-0.1 -3,-0.2 -0.524 54.2-154.0 -86.2 150.1 -17.0 8.3 28.1 82 85 A D - 0 0 130 -2,-0.2 2,-0.1 53,-0.1 -1,-0.0 -0.966 66.7 -0.3-110.3 131.9 -17.5 11.9 28.7 83 86 A G S S- 0 0 42 -2,-0.4 2,-0.4 38,-0.1 -5,-0.3 -0.405 99.0 -47.2 89.8-175.7 -18.4 14.0 25.7 84 87 A T - 0 0 37 -7,-0.1 38,-2.5 -2,-0.1 2,-0.5 -0.891 42.2-162.3-113.6 129.3 -18.9 13.0 22.1 85 88 A Y E -HI 76 121B 4 -9,-2.4 -9,-2.5 -2,-0.4 2,-0.4 -0.956 12.4-144.0-116.9 127.3 -16.6 10.8 20.0 86 89 A R E -HI 75 120B 47 34,-3.1 34,-1.9 -2,-0.5 2,-0.3 -0.709 16.8-119.9 -93.9 137.8 -16.7 10.8 16.2 87 90 A L E + I 0 119B 2 -13,-2.7 32,-0.2 -2,-0.4 -13,-0.2 -0.566 37.1 164.4 -67.5 128.7 -16.2 7.8 14.0 88 91 A I E - 0 0 34 30,-2.6 -21,-2.5 1,-0.4 2,-0.3 0.658 59.4 -23.6-114.9 -33.6 -13.3 8.3 11.7 89 92 A Q E -GI 66 118B 35 29,-1.2 29,-2.6 -23,-0.2 -1,-0.4 -0.993 46.8-145.1-165.5 163.2 -12.5 4.7 10.4 90 93 A F E +GI 65 117B 0 -25,-1.9 -25,-2.8 -2,-0.3 2,-0.3 -0.972 21.8 164.6-135.3 157.3 -12.8 1.0 11.1 91 94 A H E -GI 64 116B 24 25,-1.8 25,-2.9 -2,-0.3 2,-0.3 -0.928 23.3-123.8-154.2 173.5 -10.4 -1.8 10.3 92 95 A F E - I 0 115B 0 -29,-0.5 2,-0.4 -2,-0.3 -29,-0.3 -0.847 2.0-151.7-123.3 162.4 -9.7 -5.4 11.3 93 96 A H E + I 0 114B 4 21,-1.8 21,-2.1 -2,-0.3 2,-0.3 -0.981 30.9 169.1-121.0 136.9 -6.9 -7.6 12.6 94 97 A W E - I 0 113B 0 -2,-0.4 146,-1.3 19,-0.2 145,-0.7 -0.936 23.3-117.8-149.0 172.5 -7.0 -11.3 11.6 95 98 A G - 0 0 0 17,-1.3 6,-0.1 5,-0.6 3,-0.1 -0.486 22.9-121.4-109.6 174.4 -5.0 -14.5 11.6 96 99 A S S S+ 0 0 44 -2,-0.2 2,-0.3 142,-0.1 5,-0.1 0.584 105.0 32.6 -81.3 -15.3 -3.5 -17.0 9.3 97 100 A L S > S- 0 0 109 3,-0.3 3,-1.5 15,-0.1 -2,-0.2 -0.928 89.9-111.1-138.5 154.0 -5.7 -19.7 10.9 98 101 A D T 3 S+ 0 0 68 -2,-0.3 48,-0.2 1,-0.3 15,-0.1 0.712 110.2 66.6 -67.4 -15.5 -9.2 -19.6 12.5 99 102 A G T 3 S+ 0 0 56 13,-0.1 2,-0.3 2,-0.1 -1,-0.3 0.322 107.5 31.8 -87.2 9.4 -7.7 -20.1 16.0 100 103 A Q < + 0 0 50 -3,-1.5 -5,-0.6 12,-0.1 -3,-0.3 -0.989 64.5 97.6-154.6 165.2 -5.9 -16.8 16.2 101 104 A G + 0 0 0 1,-0.6 13,-0.3 -2,-0.3 11,-0.2 0.028 55.4 106.5 142.5 -34.1 -6.3 -13.3 14.9 102 105 A S - 0 0 1 9,-1.9 -1,-0.6 11,-0.3 12,-0.1 -0.389 54.0-150.5 -78.7 161.9 -7.8 -11.2 17.6 103 106 A E S S+ 0 0 2 -10,-0.1 -1,-0.1 -3,-0.1 2,-0.1 0.871 83.6 51.5 -92.7 -56.0 -5.7 -8.7 19.6 104 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.487 75.8-158.0 -75.8 156.3 -7.7 -8.9 22.9 105 108 A T E -a 29 0A 13 -77,-1.3 -75,-2.9 -2,-0.1 2,-0.5 -0.897 11.5-138.1-127.4 162.7 -8.3 -12.3 24.3 106 109 A V E > S-aB 30 109A 20 3,-1.8 3,-2.1 -2,-0.3 -75,-0.2 -0.969 88.0 -21.1-123.2 112.5 -10.9 -13.4 26.8 107 110 A D T 3 S- 0 0 68 -77,-2.8 -1,-0.2 -2,-0.5 -76,-0.1 0.918 128.1 -55.1 47.5 48.2 -9.6 -15.8 29.5 108 111 A K T 3 S+ 0 0 162 1,-0.2 2,-0.4 -78,-0.1 -1,-0.3 0.358 106.3 137.6 66.7 1.4 -6.7 -16.4 27.1 109 112 A K B < -B 106 0A 116 -3,-2.1 -3,-1.8 -9,-0.0 2,-0.4 -0.587 42.0-150.4 -75.5 131.3 -9.2 -17.4 24.3 110 113 A K - 0 0 92 -2,-0.4 2,-0.2 -11,-0.2 -5,-0.1 -0.799 5.4-149.0 -98.7 144.2 -8.3 -16.0 20.9 111 114 A Y - 0 0 27 -7,-0.4 -9,-1.9 -2,-0.4 34,-0.2 -0.588 27.9-107.6-104.7 171.0 -10.9 -15.2 18.2 112 115 A A S S- 0 0 3 32,-1.4 -17,-1.3 -11,-0.2 2,-0.3 0.737 93.0 -14.1 -73.1 -25.4 -10.5 -15.4 14.4 113 116 A A E -IJ 94 144B 0 31,-1.2 31,-2.6 -19,-0.2 2,-0.4 -0.975 58.6-135.0-167.0 168.5 -10.4 -11.6 14.0 114 117 A E E -IJ 93 143B 0 -21,-2.1 -21,-1.8 -13,-0.3 2,-0.4 -0.991 11.8-147.4-141.0 128.7 -11.1 -8.3 15.8 115 118 A L E -IJ 92 142B 0 27,-3.1 27,-2.4 -2,-0.4 2,-0.5 -0.831 11.8-161.8 -93.5 132.0 -13.0 -5.3 14.4 116 119 A H E -IJ 91 141B 3 -25,-2.9 -25,-1.8 -2,-0.4 2,-0.6 -0.989 6.5-167.1-118.4 117.5 -11.9 -1.8 15.7 117 120 A L E -IJ 90 140B 0 23,-2.6 23,-2.5 -2,-0.5 2,-0.4 -0.939 20.3-152.6 -98.5 112.0 -14.2 1.2 15.3 118 121 A V E +IJ 89 139B 12 -29,-2.6 -30,-2.6 -2,-0.6 -29,-1.2 -0.793 17.9 176.7 -97.6 128.7 -12.0 4.2 16.0 119 122 A H E -IJ 87 138B 0 19,-2.2 19,-2.4 -2,-0.4 2,-0.4 -0.942 14.5-148.7-129.6 147.8 -13.5 7.4 17.4 120 123 A W E -IJ 86 137B 6 -34,-1.9 -34,-3.1 -2,-0.3 2,-0.5 -0.927 27.1-105.8-125.4 148.0 -12.0 10.7 18.5 121 124 A N E > -I 85 0B 0 15,-2.8 3,-2.1 -2,-0.4 -36,-0.2 -0.550 23.3-148.7 -72.1 115.5 -13.0 13.2 21.1 122 125 A T G > S+ 0 0 38 -38,-2.5 3,-1.9 -2,-0.5 -1,-0.1 0.693 88.0 77.0 -66.5 -15.3 -14.5 16.2 19.4 123 127 A K G 3 S+ 0 0 112 -39,-0.3 -1,-0.3 1,-0.3 -38,-0.1 0.738 90.8 56.7 -67.4 -12.9 -13.4 18.5 22.2 124 128 A Y G < S- 0 0 55 -3,-2.1 2,-1.9 12,-0.1 -1,-0.3 0.366 101.7-135.7 -97.6 3.7 -9.8 18.4 20.7 125 129 A G S < S+ 0 0 56 -3,-1.9 2,-0.3 -4,-0.1 -3,-0.1 -0.060 72.9 31.4 77.7 -41.0 -11.0 19.6 17.3 126 130 A D S >> S- 0 0 69 -2,-1.9 4,-2.0 -5,-0.2 3,-0.6 -0.992 79.4-111.5-148.6 163.8 -9.1 17.1 15.2 127 131 A F H 3> S+ 0 0 69 -2,-0.3 4,-1.8 1,-0.2 -1,-0.1 0.862 113.4 56.9 -55.3 -44.1 -7.8 13.5 15.2 128 132 A G H 34 S+ 0 0 33 1,-0.2 -1,-0.2 2,-0.2 4,-0.2 0.795 110.8 43.4 -66.0 -29.0 -4.1 14.5 15.4 129 133 A K H X4 S+ 0 0 109 -3,-0.6 3,-1.3 -5,-0.2 -1,-0.2 0.865 109.4 59.0 -75.8 -38.3 -4.7 16.6 18.5 130 134 A A H >< S+ 0 0 0 -4,-2.0 3,-2.2 1,-0.3 -2,-0.2 0.846 95.9 60.2 -61.1 -38.4 -6.8 13.9 20.1 131 135 A V T 3< S+ 0 0 21 -4,-1.8 -1,-0.3 1,-0.3 -2,-0.1 0.639 97.9 61.3 -71.5 -8.7 -4.1 11.2 20.0 132 136 A Q T < S+ 0 0 137 -3,-1.3 -1,-0.3 -4,-0.2 -2,-0.2 0.391 94.4 80.2 -90.0 3.2 -2.0 13.4 22.2 133 137 A Q S X S- 0 0 68 -3,-2.2 3,-1.6 69,-0.1 4,-0.3 -0.853 79.0-131.5-116.0 145.9 -4.6 13.3 25.0 134 138 A P T 3 S+ 0 0 77 0, 0.0 58,-0.2 0, 0.0 3,-0.1 0.750 113.7 34.4 -65.6 -23.5 -5.2 10.5 27.6 135 139 A D T 3 S+ 0 0 58 1,-0.1 -14,-0.1 -5,-0.1 -53,-0.1 -0.122 89.3 110.4-115.1 29.7 -8.9 10.6 26.8 136 140 A G S < S+ 0 0 0 -3,-1.6 -15,-2.8 -6,-0.2 2,-0.3 0.869 71.6 36.8 -80.9 -30.0 -8.6 11.4 23.1 137 141 A L E -Jk 120 203B 0 65,-3.0 67,-2.4 -4,-0.3 2,-0.4 -0.872 53.1-164.7-120.5 154.2 -9.7 8.2 21.4 138 142 A A E -Jk 119 204B 0 -19,-2.4 -19,-2.2 -2,-0.3 2,-0.5 -0.992 12.7-166.4-132.7 124.5 -12.4 5.6 22.1 139 143 A V E -Jk 118 205B 3 65,-1.8 67,-2.5 -2,-0.4 2,-0.6 -0.968 10.3-149.5-116.2 125.3 -12.1 2.3 20.2 140 144 A L E -Jk 117 206B 0 -23,-2.5 -23,-2.6 -2,-0.5 2,-0.5 -0.851 17.4-159.8 -87.9 119.0 -15.0 -0.1 20.0 141 145 A G E -Jk 116 207B 0 65,-3.0 67,-3.0 -2,-0.6 2,-0.4 -0.912 11.1-178.3-108.0 131.6 -13.6 -3.7 19.7 142 146 A I E -J 115 0B 0 -27,-2.4 -27,-3.1 -2,-0.5 2,-0.2 -0.988 19.6-134.9-129.2 130.8 -15.7 -6.5 18.4 143 147 A F E -J 114 0B 0 -2,-0.4 69,-2.8 65,-0.4 2,-0.5 -0.613 12.1-148.1 -83.6 147.6 -14.6 -10.1 18.2 144 148 A L E -Jl 113 212B 0 -31,-2.6 -32,-1.4 -2,-0.2 -31,-1.2 -0.962 13.9-175.4-111.6 131.1 -15.2 -12.3 15.1 145 149 A K E - l 0 213B 96 67,-2.6 69,-2.4 -2,-0.5 2,-0.5 -0.910 30.6-109.0-121.2 155.1 -15.8 -16.0 15.3 146 150 A V E S+ l 0 214B 50 -2,-0.3 69,-0.2 67,-0.2 2,-0.2 -0.691 74.4 86.6 -88.7 128.0 -16.2 -18.4 12.4 147 151 A G S S+ 0 0 43 67,-2.5 69,-0.5 -2,-0.5 2,-0.2 -0.525 78.9 17.6-171.8-114.3 -19.7 -19.8 11.9 148 152 A S S S- 0 0 89 -2,-0.2 -1,-0.2 67,-0.1 -3,-0.1 -0.576 84.9 -96.8 -84.4 145.1 -22.6 -18.3 9.9 149 153 A A - 0 0 55 65,-0.3 65,-0.1 -2,-0.2 -1,-0.1 -0.102 25.8-132.8 -55.9 151.0 -22.0 -15.5 7.4 150 154 A K >> - 0 0 41 1,-0.2 3,-1.6 62,-0.1 4,-0.7 -0.924 13.4-161.2-106.2 107.7 -22.5 -11.9 8.3 151 155 A P G >4 S+ 0 0 111 0, 0.0 3,-1.4 0, 0.0 4,-0.4 0.895 87.3 59.4 -59.9 -40.1 -24.6 -10.4 5.6 152 156 A G G 34 S+ 0 0 26 27,-0.4 4,-0.2 1,-0.3 27,-0.1 0.594 102.7 55.0 -65.7 -10.3 -23.6 -6.8 6.5 153 157 A L G X> S+ 0 0 2 -3,-1.6 4,-2.1 1,-0.1 3,-0.8 0.664 83.7 84.4 -90.9 -16.6 -19.9 -7.6 6.0 154 158 A Q H S+ 0 0 89 -4,-0.4 4,-0.9 1,-0.2 -1,-0.3 0.893 109.9 45.4 -56.8 -38.8 -20.1 -5.4 0.8 156 160 A V H X> S+ 0 0 0 -3,-0.8 3,-0.8 -4,-0.2 4,-0.7 0.947 111.7 50.6 -67.5 -47.2 -16.6 -5.1 2.4 157 161 A V H >< S+ 0 0 2 -4,-2.1 3,-0.9 1,-0.2 4,-0.3 0.906 105.6 58.1 -58.9 -39.3 -15.5 -8.5 1.4 158 162 A D H 3< S+ 0 0 97 -4,-2.7 3,-0.4 1,-0.2 -1,-0.2 0.748 105.3 47.1 -67.6 -26.2 -16.6 -7.9 -2.2 159 163 A V H X< S+ 0 0 35 -4,-0.9 3,-2.4 -3,-0.8 4,-0.3 0.573 82.9 94.5 -89.6 -8.1 -14.3 -4.9 -2.8 160 164 A L G X< S+ 0 0 7 -3,-0.9 3,-1.7 -4,-0.7 -1,-0.2 0.821 75.6 64.9 -59.6 -28.6 -11.2 -6.4 -1.3 161 165 A D G > S+ 0 0 127 -3,-0.4 3,-0.8 -4,-0.3 -1,-0.3 0.791 97.3 56.8 -56.5 -35.9 -10.0 -7.5 -4.8 162 166 A S G < S+ 0 0 66 -3,-2.4 -1,-0.3 1,-0.2 -2,-0.2 0.415 112.9 38.4 -84.3 3.7 -9.8 -3.9 -5.8 163 167 A I G < S+ 0 0 0 -3,-1.7 -1,-0.2 -4,-0.3 63,-0.2 -0.193 71.7 137.7-139.6 45.8 -7.3 -3.0 -3.0 164 168 A K < + 0 0 79 -3,-0.8 62,-2.5 61,-0.1 2,-0.2 0.844 61.5 47.6 -65.7 -34.3 -5.2 -6.0 -2.9 165 169 A T S > S- 0 0 16 60,-0.2 3,-1.9 1,-0.1 -107,-0.3 -0.704 99.1 -74.5-114.1 162.6 -1.8 -4.3 -2.5 166 170 A K T 3 S+ 0 0 114 62,-2.5 64,-0.5 1,-0.3 -107,-0.2 -0.225 113.9 19.8 -54.4 132.4 -0.4 -1.5 -0.3 167 171 A G T 3 S+ 0 0 54 -109,-2.7 2,-0.3 1,-0.3 -1,-0.3 0.238 88.9 128.2 89.8 -10.7 -1.5 2.0 -1.3 168 172 A K < + 0 0 82 -3,-1.9 -110,-2.8 -110,-0.2 -1,-0.3 -0.583 31.9 177.4 -78.2 142.5 -4.6 1.0 -3.3 169 173 A S E -F 57 0B 55 -2,-0.3 2,-0.3 -112,-0.2 -112,-0.2 -0.931 10.9-164.1-138.1 160.7 -7.9 2.6 -2.4 170 174 A A E -F 56 0B 24 -114,-2.2 -114,-2.6 -2,-0.3 2,-0.1 -0.991 34.7 -96.4-144.5 147.9 -11.4 2.5 -3.8 171 175 A D E +F 55 0B 153 -2,-0.3 -116,-0.3 -116,-0.2 2,-0.2 -0.396 41.6 179.7 -56.7 133.0 -14.6 4.7 -3.4 172 176 A F + 0 0 8 -118,-2.5 3,-0.4 -2,-0.1 2,-0.2 -0.579 12.1 163.8-144.1 78.4 -16.7 3.1 -0.7 173 177 A T + 0 0 78 1,-0.2 -119,-0.2 -2,-0.2 -121,-0.1 -0.587 51.7 22.4-102.2 160.7 -19.9 5.0 -0.2 174 178 A N S S+ 0 0 143 -121,-0.5 2,-0.5 1,-0.2 -1,-0.2 0.752 73.3 151.9 56.7 35.7 -23.2 4.3 1.5 175 179 A F - 0 0 8 -3,-0.4 -122,-0.4 -20,-0.0 -1,-0.2 -0.832 35.4-148.4 -92.6 131.0 -21.8 1.5 3.8 176 180 A D > - 0 0 67 -2,-0.5 3,-1.6 1,-0.1 4,-0.1 -0.859 7.2-162.4-102.3 107.3 -23.8 1.3 7.0 177 181 A P G > S+ 0 0 0 0, 0.0 3,-2.1 0, 0.0 4,-0.2 0.666 79.6 82.3 -71.4 -7.5 -21.6 0.2 9.9 178 182 A R G > S+ 0 0 123 1,-0.3 3,-1.5 -130,-0.2 -26,-0.1 0.816 78.8 68.7 -61.6 -25.7 -24.7 -0.8 12.0 179 183 A G G < S+ 0 0 33 -3,-1.6 -27,-0.4 1,-0.3 -1,-0.3 0.527 94.0 58.6 -71.3 -0.9 -24.7 -4.0 10.1 180 184 A L G < S+ 0 0 1 -3,-2.1 -1,-0.3 -28,-0.1 -2,-0.2 0.379 84.1 102.4-104.2 -2.7 -21.5 -5.0 11.9 181 185 A L < - 0 0 33 -3,-1.5 4,-0.1 -4,-0.2 -39,-0.0 -0.585 67.8-125.2 -89.4 144.6 -22.8 -4.8 15.5 182 186 A P - 0 0 11 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.214 31.2-105.4 -73.7 175.9 -23.8 -7.7 17.7 183 187 A E S S+ 0 0 179 2,-0.0 2,-0.3 1,-0.0 29,-0.0 0.912 103.1 52.5 -70.5 -42.9 -27.3 -7.8 19.3 184 188 A S - 0 0 29 1,-0.1 26,-0.3 2,-0.1 -1,-0.0 -0.744 62.1-159.4 -96.7 143.4 -26.1 -6.9 22.8 185 189 A L + 0 0 56 -2,-0.3 -141,-0.3 23,-0.1 -1,-0.1 0.132 43.5 137.3-107.3 21.1 -23.9 -3.9 23.7 186 190 A D + 0 0 57 -143,-0.1 23,-2.2 22,-0.1 24,-0.5 -0.387 34.4 174.4 -61.1 145.6 -22.6 -5.2 27.1 187 191 A Y E -M 208 0B 2 21,-0.3 68,-2.7 22,-0.1 2,-0.3 -0.933 37.7-128.7-150.6 166.5 -18.9 -4.4 27.3 188 192 A W E -MN 207 254B 13 19,-2.6 19,-2.6 -2,-0.3 2,-0.3 -0.869 29.9-164.5-110.4 152.6 -15.7 -4.4 29.2 189 193 A T E +MN 206 253B 7 64,-2.8 64,-3.0 -2,-0.3 17,-0.2 -0.999 17.0 155.1-143.4 147.9 -13.6 -1.2 29.4 190 194 A Y E -M 205 0B 5 15,-1.4 15,-2.6 -2,-0.3 2,-0.4 -0.960 44.7-100.1-161.0 153.1 -10.0 -0.2 30.4 191 195 A P E +M 204 0B 52 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.682 61.3 132.6 -78.5 130.4 -7.6 2.6 29.6 192 196 A G E -M 203 0B 0 11,-3.6 11,-1.5 -2,-0.4 2,-0.2 -0.560 41.5 -89.5-152.0-144.6 -5.0 1.6 27.0 193 197 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 7,-0.1 -0.811 43.2 -78.0-136.8 169.3 -3.2 2.4 23.8 194 198 A L - 0 0 32 6,-2.2 -168,-0.5 -2,-0.2 9,-0.0 -0.486 40.9-139.2 -61.9 148.3 -3.1 2.2 20.0 195 199 A T S S+ 0 0 6 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.439 82.3 48.1-101.0 3.3 -2.1 -1.3 19.1 196 200 A T S > S- 0 0 39 4,-0.1 3,-2.5 46,-0.0 4,-0.2 -0.932 104.5 -39.3-127.1 160.5 0.2 -0.4 16.2 197 201 A P T 3 S+ 0 0 11 0, 0.0 -2,-0.1 0, 0.0 -1,-0.0 -0.220 124.1 42.5 -50.2 141.6 2.9 2.3 16.1 198 202 A P T 3 S- 0 0 66 0, 0.0 -179,-0.1 0, 0.0 -178,-0.0 -0.975 83.4-163.9 -80.2 8.4 3.0 5.0 17.3 199 203 A L < - 0 0 0 -3,-2.5 -173,-0.1 1,-0.2 -4,-0.0 0.731 18.7-178.8 62.4 25.1 1.4 3.1 20.2 200 204 A L - 0 0 56 -4,-0.2 -6,-2.2 -7,-0.1 2,-1.5 -0.233 32.0-127.8 -61.6 141.3 0.2 6.3 21.9 201 205 A E S S+ 0 0 49 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.485 74.8 110.2 -90.1 71.4 -1.6 5.8 25.2 202 206 A C + 0 0 1 -2,-1.5 -65,-3.0 -67,-0.1 2,-0.4 0.122 47.6 109.6-129.9 14.7 -4.7 7.8 24.3 203 207 A V E -kM 137 192B 0 -11,-1.5 -11,-3.6 -3,-0.2 2,-0.7 -0.887 49.4-159.4-115.0 132.5 -7.4 5.2 24.1 204 208 A T E -kM 138 191B 27 -67,-2.4 -65,-1.8 -2,-0.4 2,-0.4 -0.936 31.6-147.1 -91.0 110.6 -10.5 4.3 26.2 205 209 A W E -kM 139 190B 4 -15,-2.6 -15,-1.4 -2,-0.7 2,-0.5 -0.711 18.3-173.5 -85.5 135.8 -11.0 0.7 25.0 206 210 A I E -kM 140 189B 0 -67,-2.5 -65,-3.0 -2,-0.4 2,-0.5 -0.976 7.6-171.7-123.3 108.7 -14.6 -0.6 24.9 207 211 A V E -kM 141 188B 1 -19,-2.6 -19,-2.6 -2,-0.5 2,-0.2 -0.929 18.7-133.4-110.8 122.3 -14.6 -4.3 24.1 208 212 A L E - M 0 187B 0 -67,-3.0 -65,-0.4 -2,-0.5 -21,-0.3 -0.533 3.6-145.8 -76.6 140.2 -18.0 -5.9 23.4 209 213 A K S S+ 0 0 70 -23,-2.2 -1,-0.1 -2,-0.2 -22,-0.1 0.833 81.0 71.5 -71.5 -33.7 -18.7 -9.2 25.2 210 214 A E S S- 0 0 58 -24,-0.5 -67,-0.2 -26,-0.3 -2,-0.1 -0.732 75.1-146.5 -90.6 121.0 -20.8 -10.7 22.3 211 215 A P - 0 0 31 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.319 9.5-130.8 -74.7 162.5 -18.8 -11.7 19.2 212 216 A I E -l 144 0B 4 -69,-2.8 -67,-2.6 -30,-0.1 2,-0.4 -0.809 22.7-130.2-102.1 154.8 -20.3 -11.5 15.7 213 217 A S E -l 145 0B 27 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.867 24.6-179.4-108.8 144.9 -20.0 -14.6 13.5 214 218 A V E -l 146 0B 0 -69,-2.4 -67,-2.5 -2,-0.4 -65,-0.3 -0.909 30.9-100.4-130.4 162.2 -18.6 -14.5 10.0 215 219 A S > - 0 0 13 -2,-0.3 4,-2.2 -69,-0.2 3,-0.3 -0.452 25.5-115.8 -86.3 161.6 -18.2 -17.4 7.5 216 220 A S H > S+ 0 0 44 -69,-0.5 4,-2.1 1,-0.2 5,-0.1 0.909 118.2 53.5 -49.4 -44.6 -15.0 -19.2 6.7 217 221 A E H > S+ 0 0 125 1,-0.2 4,-1.2 2,-0.2 -1,-0.2 0.824 105.1 53.6 -63.9 -37.8 -15.3 -17.9 3.2 218 222 A Q H >> S+ 0 0 5 -3,-0.3 4,-0.9 1,-0.2 3,-0.5 0.953 112.2 42.5 -64.8 -49.0 -15.6 -14.3 4.4 219 223 A V H 3X S+ 0 0 1 -4,-2.2 4,-1.4 1,-0.2 3,-0.4 0.852 106.3 63.5 -66.5 -30.0 -12.4 -14.4 6.5 220 224 A L H 3< S+ 0 0 81 -4,-2.1 4,-0.2 -5,-0.3 -1,-0.2 0.891 98.0 56.5 -61.9 -33.3 -10.6 -16.3 3.8 221 225 A K H X< S+ 0 0 78 -4,-1.2 3,-1.1 -3,-0.5 -1,-0.3 0.841 101.4 56.9 -67.9 -29.9 -11.0 -13.3 1.5 222 226 A F H >< S+ 0 0 0 -4,-0.9 3,-1.3 -3,-0.4 -1,-0.2 0.880 101.4 57.7 -61.7 -39.1 -9.3 -11.2 4.2 223 227 A R T 3< S+ 0 0 29 -4,-1.4 -1,-0.2 1,-0.3 -2,-0.2 0.470 92.7 68.5 -72.0 -3.8 -6.3 -13.5 4.0 224 228 A K T < S+ 0 0 121 -3,-1.1 -1,-0.3 -4,-0.2 -2,-0.2 0.486 78.1 103.9 -96.2 -1.3 -5.8 -12.9 0.2 225 229 A L < - 0 0 2 -3,-1.3 12,-3.2 12,-0.3 2,-0.4 -0.293 66.7-127.6 -72.4 166.9 -4.7 -9.3 0.8 226 230 A N B -O 236 0C 5 -62,-2.5 -166,-0.2 10,-0.3 10,-0.2 -0.938 15.7-157.9-120.8 140.6 -1.1 -8.3 0.5 227 231 A F S S+ 0 0 41 8,-2.3 9,-0.1 -2,-0.4 -1,-0.1 0.808 80.2 76.1 -74.8 -35.1 1.2 -6.4 2.8 228 232 A N S S- 0 0 15 7,-0.6 -62,-2.5 5,-0.1 2,-0.2 -0.225 85.5-111.1 -74.4 164.8 3.4 -5.5 -0.2 229 233 A G > - 0 0 8 -64,-0.3 3,-1.9 1,-0.2 -62,-0.1 -0.521 50.7 -72.3 -92.6 164.8 2.8 -2.9 -2.9 230 234 A E T 3 S+ 0 0 139 -64,-0.5 -1,-0.2 1,-0.3 4,-0.0 -0.185 120.6 24.5 -54.5 140.8 2.1 -3.8 -6.5 231 235 A G T 3 S+ 0 0 83 1,-0.3 -1,-0.3 -3,-0.1 3,-0.1 0.178 103.6 104.7 89.6 -25.1 5.1 -5.1 -8.4 232 236 A E S < S- 0 0 108 -3,-1.9 -1,-0.3 1,-0.2 2,-0.1 -0.387 86.8 -70.9 -87.8 170.3 6.8 -6.3 -5.2 233 237 A P - 0 0 112 0, 0.0 2,-0.3 0, 0.0 -1,-0.2 -0.353 59.4-106.7 -57.4 131.6 7.2 -9.8 -3.9 234 238 A E + 0 0 111 -3,-0.1 2,-0.4 -2,-0.1 -8,-0.0 -0.464 41.4 172.7 -68.3 123.6 3.9 -11.2 -2.6 235 239 A E - 0 0 127 -2,-0.3 -8,-2.3 -3,-0.1 -7,-0.6 -0.974 32.1-126.5-129.1 116.9 3.5 -11.4 1.1 236 240 A L B -O 226 0C 77 -2,-0.4 2,-1.4 -10,-0.2 -10,-0.3 -0.348 19.2-119.5 -71.3 142.6 0.0 -12.3 2.3 237 241 A M + 0 0 0 -12,-3.2 -12,-0.3 -15,-0.2 2,-0.3 -0.657 63.4 130.4 -83.6 94.5 -1.6 -10.0 4.8 238 242 A V + 0 0 33 -2,-1.4 -143,-0.2 1,-0.1 -142,-0.1 -0.969 52.0 24.6-143.5 157.2 -2.1 -12.3 7.7 239 243 A D + 0 0 41 -145,-0.7 2,-0.7 -2,-0.3 -144,-0.2 0.907 62.3 158.5 55.4 48.2 -1.5 -12.3 11.5 240 244 A N + 0 0 1 -146,-1.3 2,-0.3 -3,-0.1 -1,-0.2 -0.263 35.8 114.0 -96.1 51.8 -1.5 -8.5 11.7 241 245 A W - 0 0 46 -2,-0.7 -139,-0.1 -148,-0.1 -138,-0.1 -0.900 61.5-133.5-121.2 150.4 -2.2 -8.6 15.4 242 246 A R - 0 0 5 -2,-0.3 3,-0.1 -233,-0.1 -2,-0.1 -0.833 31.1-115.7 -99.8 137.4 -0.2 -7.6 18.5 243 247 A P - 0 0 42 0, 0.0 -140,-0.1 0, 0.0 -139,-0.1 -0.309 44.2 -75.4 -72.7 160.5 -0.0 -10.0 21.4 244 248 A A - 0 0 50 -141,-0.1 -216,-0.3 1,-0.1 -218,-0.1 -0.160 48.8-147.6 -54.4 137.9 -1.5 -9.3 24.8 245 249 A Q - 0 0 38 -218,-2.6 -216,-0.4 -220,-0.1 -1,-0.1 -0.715 31.8 -78.4-107.1 159.0 0.5 -6.9 26.9 246 250 A P - 0 0 77 0, 0.0 -221,-0.3 0, 0.0 -1,-0.1 -0.338 30.7-142.2 -63.4 137.3 0.9 -6.7 30.8 247 251 A L + 0 0 51 1,-0.2 3,-0.4 -223,-0.1 -219,-0.0 0.827 37.2 170.8 -71.2 -27.9 -2.0 -5.2 32.5 248 252 A K - 0 0 92 1,-0.2 2,-1.5 -224,-0.1 -1,-0.2 -0.257 65.3 -5.3 54.5-143.5 0.3 -3.5 35.0 249 253 A N S S+ 0 0 146 -226,-0.2 2,-0.3 2,-0.0 -1,-0.2 -0.162 108.0 112.5 -77.2 44.5 -1.6 -1.0 37.3 250 254 A R - 0 0 25 -2,-1.5 2,-0.4 -3,-0.4 -3,-0.1 -0.875 51.3-150.9-123.9 153.2 -5.0 -1.3 35.5 251 255 A Q - 0 0 140 -2,-0.3 2,-0.5 -216,-0.0 -216,-0.1 -0.964 14.7-141.3-115.1 131.7 -8.5 -2.6 36.4 252 256 A I - 0 0 11 -2,-0.4 -216,-2.4 -218,-0.2 2,-0.4 -0.823 20.3-154.9 -89.3 131.4 -10.8 -3.9 33.7 253 257 A K E -cN 36 189B 88 -64,-3.0 -64,-2.8 -2,-0.5 2,-0.4 -0.858 1.7-150.4-107.9 148.5 -14.4 -2.9 34.4 254 258 A A E -cN 37 188B 5 -218,-2.6 -216,-2.8 -2,-0.4 -66,-0.2 -0.909 12.2-152.7-115.3 139.8 -17.5 -4.7 33.2 255 259 A S S S+ 0 0 27 -68,-2.7 2,-0.3 -2,-0.4 -67,-0.1 0.345 81.2 55.7 -87.7 4.5 -20.9 -3.1 32.4 256 260 A F 0 0 47 -69,-0.3 -218,-0.1 -70,-0.0 -2,-0.1 -0.976 360.0 360.0-144.1 150.1 -22.7 -6.4 33.2 257 261 A K 0 0 208 -2,-0.3 -221,-0.0 -220,-0.1 -2,-0.0 -0.852 360.0 360.0-127.8 360.0 -23.0 -8.9 36.0