==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 31-DEC-05 2DC8 . COMPND 2 MOLECULE: CATHEPSIN B; . SOURCE 2 ORGANISM_SCIENTIFIC: BOS TAURUS; . AUTHOR D.WATANABE . 251 2 7 6 1 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11060.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 154 61.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 7 2.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 48 19.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 20 8.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 27 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 43 17.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 0 1 0 0 1 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 6 1 0 0 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A L 0 0 116 0, 0.0 4,-0.1 0, 0.0 160,-0.1 0.000 360.0 360.0 360.0 140.2 20.1 47.1 3.2 2 2 A P - 0 0 49 0, 0.0 3,-0.0 0, 0.0 0, 0.0 -0.233 360.0-116.2 -68.3 160.8 16.5 48.4 2.5 3 3 A E S S+ 0 0 139 1,-0.1 2,-0.3 204,-0.0 0, 0.0 0.783 100.1 21.5 -67.9 -28.3 13.5 47.1 4.4 4 4 A S - 0 0 63 202,-0.1 2,-0.3 2,-0.0 202,-0.3 -0.953 64.6-179.0-138.5 156.9 12.1 45.8 1.1 5 5 A F E -A 205 0A 7 200,-2.7 200,-2.2 -2,-0.3 2,-0.5 -0.921 6.8-173.3-160.2 130.1 13.5 44.9 -2.3 6 6 A D E >> -A 204 0A 23 -2,-0.3 4,-2.1 198,-0.2 3,-1.4 -0.929 13.6-157.8-130.4 106.7 11.9 43.7 -5.5 7 7 A A H 3> S+ 0 0 0 196,-2.5 4,-1.8 -2,-0.5 -1,-0.1 0.774 93.8 64.0 -53.3 -28.2 14.3 42.7 -8.3 8 8 A R H 34 S+ 0 0 67 195,-0.2 -1,-0.3 1,-0.2 6,-0.2 0.887 110.2 36.5 -64.1 -39.0 11.4 43.3 -10.8 9 9 A E H <4 S+ 0 0 140 -3,-1.4 -2,-0.2 1,-0.2 -1,-0.2 0.811 115.8 53.9 -82.2 -34.1 11.3 47.0 -9.9 10 10 A Q H < S+ 0 0 105 -4,-2.1 -2,-0.2 1,-0.3 -3,-0.2 0.769 116.5 35.9 -74.1 -27.8 15.1 47.4 -9.5 11 11 A W >< + 0 0 55 -4,-1.8 3,-1.8 -5,-0.2 -1,-0.3 -0.611 66.4 165.4-127.1 71.8 16.0 46.0 -12.9 12 12 A P T 3 S+ 0 0 84 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 0.697 73.3 63.4 -58.3 -24.8 13.2 47.2 -15.2 13 13 A N T 3 S+ 0 0 122 1,-0.2 -5,-0.1 -3,-0.1 -3,-0.0 0.354 90.3 73.3 -85.8 7.5 15.2 46.3 -18.3 14 14 A a X + 0 0 3 -3,-1.8 3,-1.6 -6,-0.2 4,-0.3 -0.727 55.3 174.2-123.1 81.1 15.2 42.6 -17.4 15 15 A P G >> S+ 0 0 65 0, 0.0 3,-1.4 0, 0.0 4,-0.7 0.697 70.9 74.2 -60.6 -21.9 11.7 41.3 -18.1 16 16 A T G >4 S+ 0 0 5 1,-0.3 3,-0.8 2,-0.2 24,-0.2 0.821 85.3 68.4 -62.7 -25.8 12.7 37.6 -17.4 17 17 A I G <4 S+ 0 0 0 -3,-1.6 -1,-0.3 1,-0.3 -9,-0.2 0.820 102.1 44.9 -61.1 -29.5 12.7 38.7 -13.7 18 18 A K G <4 S+ 0 0 125 -3,-1.4 -1,-0.3 -4,-0.3 -2,-0.2 0.589 94.7 107.4 -89.0 -13.4 8.9 39.1 -13.9 19 19 A E << - 0 0 73 -3,-0.8 2,-0.4 -4,-0.7 -3,-0.0 -0.341 50.8-160.5 -72.4 147.8 8.4 35.8 -15.8 20 20 A I - 0 0 23 -2,-0.1 202,-0.2 199,-0.0 2,-0.1 -0.997 13.7-163.4-126.5 127.0 6.8 32.7 -14.3 21 21 A R - 0 0 12 -2,-0.4 200,-2.2 197,-0.4 2,-0.4 -0.455 16.0-126.4-104.1 179.2 7.5 29.4 -16.1 22 22 A D B -I 220 0B 13 198,-0.2 198,-0.2 -2,-0.1 71,-0.2 -0.951 9.1-166.6-132.4 111.7 5.8 25.9 -15.9 23 23 A Q - 0 0 12 196,-2.5 5,-0.2 -2,-0.4 197,-0.1 0.583 34.4-154.7 -72.4 -9.5 8.0 22.9 -15.3 24 24 A G - 0 0 3 195,-0.3 2,-1.8 1,-0.2 -1,-0.2 -0.215 52.4 -23.8 68.0-160.3 5.1 20.6 -16.3 25 25 A S S S+ 0 0 21 80,-0.5 2,-0.3 -3,-0.1 -1,-0.2 -0.541 112.9 94.6 -86.7 72.2 4.7 17.0 -15.2 26 26 A b S S- 0 0 8 -2,-1.8 2,-2.1 78,-0.1 3,-0.1 -0.942 80.1-122.4-162.0 135.5 8.4 16.6 -14.4 27 27 A G B +j 71 0C 27 43,-1.9 45,-0.6 95,-0.3 3,-0.3 -0.309 69.2 126.1 -80.3 57.5 10.4 17.0 -11.2 28 28 A S >> + 0 0 0 -2,-2.1 4,-2.2 -5,-0.2 3,-1.0 0.117 19.2 119.6-102.5 21.5 12.7 19.6 -12.8 29 29 A C H 3> S+ 0 0 16 1,-0.3 4,-2.8 2,-0.2 5,-0.3 0.853 72.6 62.2 -54.6 -34.3 12.3 22.4 -10.3 30 30 A W H 3> S+ 0 0 5 -3,-0.3 4,-1.0 1,-0.2 -1,-0.3 0.893 108.7 41.7 -57.5 -39.8 16.1 22.2 -9.7 31 31 A A H <> S+ 0 0 0 -3,-1.0 4,-2.7 2,-0.2 5,-0.2 0.873 114.4 50.9 -75.3 -40.2 16.7 23.1 -13.3 32 32 A F H X S+ 0 0 3 -4,-2.2 4,-2.2 2,-0.2 5,-0.3 0.929 106.1 52.2 -66.5 -45.9 14.0 25.8 -13.5 33 33 A G H X S+ 0 0 0 -4,-2.8 4,-1.7 1,-0.2 -1,-0.2 0.902 115.3 46.5 -56.5 -37.6 15.1 27.7 -10.4 34 34 A A H X S+ 0 0 0 -4,-1.0 4,-2.8 -5,-0.3 -2,-0.2 0.966 112.6 43.0 -69.6 -57.6 18.5 27.8 -12.0 35 35 A V H X S+ 0 0 0 -4,-2.7 4,-2.2 1,-0.2 18,-0.4 0.805 113.7 54.7 -63.6 -27.0 17.8 28.8 -15.6 36 36 A E H X S+ 0 0 9 -4,-2.2 4,-2.1 -5,-0.2 -1,-0.2 0.965 113.1 39.7 -69.4 -52.2 15.3 31.5 -14.4 37 37 A A H X S+ 0 0 0 -4,-1.7 4,-2.7 -5,-0.3 -2,-0.2 0.867 115.5 53.8 -64.5 -35.8 17.9 33.1 -12.1 38 38 A I H X S+ 0 0 0 -4,-2.8 4,-2.5 2,-0.2 -1,-0.2 0.914 106.5 51.2 -65.7 -41.3 20.6 32.7 -14.7 39 39 A S H X S+ 0 0 0 -4,-2.2 4,-1.6 -5,-0.2 12,-0.4 0.930 111.5 48.9 -59.7 -44.6 18.4 34.4 -17.3 40 40 A D H X S+ 0 0 1 -4,-2.1 4,-2.6 1,-0.2 -2,-0.2 0.935 113.0 46.5 -60.0 -48.5 17.9 37.3 -14.9 41 41 A R H X S+ 0 0 0 -4,-2.7 4,-2.9 2,-0.2 -1,-0.2 0.821 105.7 57.8 -66.6 -33.4 21.7 37.5 -14.1 42 42 A I H < S+ 0 0 9 -4,-2.5 -1,-0.2 2,-0.2 -2,-0.2 0.917 112.9 42.6 -62.9 -39.8 22.7 37.4 -17.8 43 43 A a H >< S+ 0 0 1 -4,-1.6 3,-0.9 -5,-0.2 -2,-0.2 0.924 114.8 49.2 -70.4 -45.7 20.5 40.5 -18.3 44 44 A I H 3< S+ 0 0 24 -4,-2.6 3,-0.5 1,-0.3 2,-0.4 0.894 117.2 41.3 -62.0 -41.1 21.7 42.2 -15.2 45 45 A H T 3< S+ 0 0 50 -4,-2.9 -1,-0.3 1,-0.2 -2,-0.1 -0.396 112.9 50.6-107.2 56.1 25.3 41.6 -15.9 46 46 A S < 0 0 37 -3,-0.9 -1,-0.2 -2,-0.4 -2,-0.1 0.110 360.0 360.0-174.1 29.9 25.4 42.4 -19.7 47 47 A N 0 0 142 -3,-0.5 -3,-0.1 2,-0.0 -2,-0.0 0.156 360.0 360.0-101.7 360.0 23.7 45.7 -20.1 48 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 49 50 A V 0 0 102 0, 0.0 2,-0.6 0, 0.0 -4,-0.1 0.000 360.0 360.0 360.0 149.1 21.4 41.2 -23.6 50 51 A N + 0 0 86 -7,-0.1 2,-0.4 -6,-0.0 -10,-0.1 -0.911 360.0 173.0-108.9 122.4 18.2 39.4 -22.8 51 52 A V - 0 0 10 -2,-0.6 2,-1.2 -12,-0.4 -8,-0.2 -0.990 32.5-142.5-133.7 131.7 18.1 35.6 -23.1 52 53 A E - 0 0 27 -2,-0.4 38,-3.0 -12,-0.0 2,-0.2 -0.784 34.3-141.8 -86.1 97.2 15.5 33.0 -22.2 53 54 A V B -K 89 0D 2 -2,-1.2 2,-0.4 -18,-0.4 36,-0.2 -0.444 21.4-107.2 -66.7 132.8 17.9 30.4 -20.9 54 55 A S > - 0 0 0 34,-2.6 4,-1.6 -2,-0.2 5,-0.1 -0.451 26.8-171.6 -67.5 113.5 16.7 26.8 -21.9 55 56 A A H > S+ 0 0 3 -2,-0.4 4,-3.1 35,-0.4 5,-0.2 0.842 91.5 59.8 -68.0 -32.6 15.3 24.8 -19.1 56 57 A E H > S+ 0 0 9 44,-0.5 4,-2.8 2,-0.2 5,-0.4 0.913 102.3 49.3 -60.8 -46.5 15.4 21.9 -21.6 57 58 A D H > S+ 0 0 0 43,-0.4 4,-2.1 2,-0.2 5,-0.4 0.924 116.6 42.2 -61.5 -45.0 19.2 22.2 -22.1 58 59 A M H X S+ 0 0 0 -4,-1.6 4,-1.4 2,-0.2 5,-0.3 0.959 116.9 47.6 -64.7 -52.4 19.8 22.1 -18.3 59 60 A L H < S+ 0 0 4 -4,-3.1 4,-0.3 1,-0.2 -2,-0.2 0.885 123.1 30.1 -56.2 -47.6 17.2 19.4 -17.6 60 61 A T H < S+ 0 0 15 -4,-2.8 67,-0.3 -5,-0.2 -1,-0.2 0.820 122.9 39.1 -89.1 -33.6 18.3 17.0 -20.3 61 62 A c H < S+ 0 0 20 -4,-2.1 -3,-0.2 -5,-0.4 -2,-0.1 0.618 93.4 75.2 -98.4 -12.0 22.0 17.5 -20.9 62 63 A d S >< S+ 0 0 15 -4,-1.4 3,-0.6 -5,-0.4 -1,-0.1 0.939 73.1 179.7 -66.6 -43.3 23.6 18.0 -17.4 63 64 A G G > - 0 0 43 -4,-0.3 3,-2.1 -5,-0.3 4,-0.4 -0.394 53.3 -12.5 81.2-157.5 23.4 14.4 -16.4 64 65 A G G > S+ 0 0 64 1,-0.3 3,-1.3 2,-0.2 -1,-0.2 0.755 122.3 71.6 -52.9 -31.3 24.5 12.9 -13.1 65 66 A E G < S+ 0 0 88 -3,-0.6 -1,-0.3 1,-0.3 -2,-0.1 0.805 108.8 36.7 -58.0 -26.4 26.4 16.0 -12.1 66 67 A d G < S- 0 0 0 -3,-2.1 8,-2.5 1,-0.2 2,-0.5 0.362 119.0-109.8-106.0 1.4 23.0 17.6 -11.5 67 68 A G B < -L 73 0E 19 -3,-1.3 6,-0.3 -4,-0.4 -1,-0.2 -0.917 63.4 -29.0 115.2-126.2 21.1 14.6 -10.2 68 69 A D > - 0 0 97 4,-3.0 3,-2.6 -2,-0.5 5,-0.1 -0.246 66.3-127.1-136.5 50.9 18.4 12.7 -12.1 69 70 A G T > S+ 0 0 10 1,-0.3 3,-1.8 -6,-0.3 -1,-0.3 -0.141 93.6 7.2 48.1-124.0 16.5 14.9 -14.5 70 71 A b T 3 S+ 0 0 9 1,-0.3 -43,-1.9 -42,-0.1 -1,-0.3 0.523 126.2 68.3 -67.6 -2.9 12.7 14.7 -14.0 71 72 A N B < S-j 27 0C 127 -3,-2.6 -1,-0.3 1,-0.4 -2,-0.2 0.317 119.6 -83.0 -96.9 6.9 13.4 12.7 -10.9 72 73 A G < - 0 0 25 -3,-1.8 -4,-3.0 -45,-0.6 -1,-0.4 -0.209 50.7-159.6 109.9 158.0 15.0 15.6 -9.0 73 74 A G B -L 67 0E 24 -6,-0.3 -6,-0.3 -5,-0.1 -7,-0.1 -0.882 25.4 -82.0-157.8-170.5 18.4 17.2 -8.9 74 75 A F >> - 0 0 117 -8,-2.5 4,-1.6 -2,-0.3 3,-0.7 -0.914 23.2-153.9-113.7 111.7 21.0 19.4 -7.3 75 76 A P H >> S+ 0 0 4 0, 0.0 4,-1.7 0, 0.0 3,-0.6 0.898 97.9 50.2 -47.7 -51.6 20.8 23.2 -7.6 76 77 A S H 3> S+ 0 0 51 1,-0.3 4,-1.6 2,-0.2 5,-0.1 0.847 107.3 57.0 -59.2 -30.9 24.5 23.8 -7.2 77 78 A G H <> S+ 0 0 2 -3,-0.7 4,-1.8 1,-0.2 -1,-0.3 0.879 102.6 54.8 -66.8 -35.5 25.1 21.2 -9.8 78 79 A A H S+ 0 0 12 -4,-1.8 4,-2.7 1,-0.2 5,-1.8 0.894 104.1 56.5 -60.5 -39.2 26.8 23.0 -15.7 82 83 A W H <5S+ 0 0 0 -4,-1.6 64,-1.8 1,-0.2 -1,-0.2 0.870 112.7 41.0 -61.0 -36.9 26.3 26.6 -16.7 83 84 A T H <5S+ 0 0 45 -4,-1.4 -1,-0.2 62,-0.3 -2,-0.2 0.808 123.1 39.2 -81.5 -30.0 30.0 27.3 -16.1 84 85 A K H <5S+ 0 0 149 -4,-2.4 -2,-0.2 -5,-0.1 -3,-0.2 0.933 137.6 6.0 -85.9 -52.3 31.3 24.0 -17.6 85 86 A K T <5S- 0 0 112 -4,-2.7 -3,-0.2 -5,-0.2 -2,-0.1 0.579 95.3-139.4-109.0 -16.3 29.1 23.4 -20.6 86 87 A G < - 0 0 0 -5,-1.8 2,-0.4 -6,-0.2 59,-0.2 -0.038 17.1 -96.2 77.8 172.3 27.1 26.6 -20.8 87 88 A L B -M 144 0F 1 57,-2.3 57,-2.2 -5,-0.2 2,-0.1 -0.993 23.6-142.6-133.8 136.8 23.4 26.8 -21.7 88 89 A V - 0 0 0 -2,-0.4 -34,-2.6 55,-0.2 -31,-0.2 -0.349 35.3 -91.2 -86.8 175.2 21.6 27.6 -25.0 89 90 A S B +K 53 0D 10 -36,-0.2 11,-2.8 53,-0.2 -36,-0.2 -0.411 49.8 156.8 -83.4 163.8 18.5 29.7 -25.3 90 91 A G - 0 0 0 -38,-3.0 -35,-0.4 9,-0.2 8,-0.3 -0.560 19.3-156.3 171.4 120.7 15.0 28.2 -25.2 91 92 A G - 0 0 5 6,-3.2 11,-2.6 1,-0.2 -35,-0.2 0.106 42.0 -43.9 -89.9-157.5 11.5 29.5 -24.4 92 93 A L S > S- 0 0 94 9,-0.2 3,-2.2 1,-0.2 4,-0.4 -0.129 77.3 -68.5 -68.3 164.2 8.2 28.1 -23.2 93 94 A Y T 3 S+ 0 0 93 1,-0.3 -1,-0.2 11,-0.2 10,-0.1 -0.294 121.2 1.7 -55.4 131.4 6.5 25.0 -24.5 94 95 A N T 3 S+ 0 0 109 8,-0.5 -1,-0.3 -3,-0.1 -2,-0.1 0.619 98.2 115.5 63.6 15.9 5.3 25.5 -28.1 95 96 A S < - 0 0 40 -3,-2.2 -2,-0.1 7,-0.2 3,-0.1 0.756 66.1-146.7 -83.1 -26.1 6.8 29.0 -28.2 96 97 A H + 0 0 130 -4,-0.4 2,-0.5 1,-0.2 -3,-0.1 0.731 49.7 144.2 62.5 23.5 9.3 28.2 -30.9 97 98 A V - 0 0 73 -5,-0.4 -6,-3.2 38,-0.0 -1,-0.2 -0.821 51.3 -14.1 -97.8 125.8 11.6 30.7 -29.1 98 99 A G S S- 0 0 9 -2,-0.5 34,-0.3 -8,-0.3 -8,-0.2 -0.096 97.1 -53.2 82.0-179.9 15.3 30.0 -28.9 99 100 A e S S+ 0 0 1 1,-0.2 33,-2.4 32,-0.1 -9,-0.2 0.934 126.7 15.4 -62.7 -52.3 17.5 27.0 -29.6 100 101 A R S S- 0 0 18 -11,-2.8 -44,-0.5 31,-0.2 -43,-0.4 -0.737 73.6-166.2-132.7 87.8 15.7 24.5 -27.3 101 102 A P - 0 0 25 0, 0.0 -9,-0.2 0, 0.0 -8,-0.1 -0.269 45.1 -80.2 -65.2 156.9 12.2 25.5 -26.1 102 103 A Y - 0 0 10 -11,-2.6 -8,-0.5 1,-0.1 -7,-0.2 -0.378 38.5-159.9 -62.5 133.6 10.8 23.4 -23.2 103 104 A S + 0 0 56 -10,-0.1 -1,-0.1 -3,-0.1 -11,-0.0 0.448 63.7 88.5 -96.5 -2.0 9.3 20.1 -24.5 104 105 A I S S- 0 0 19 -82,-0.1 -11,-0.2 18,-0.0 -82,-0.1 -0.884 81.2-117.8-103.5 121.9 7.1 19.2 -21.6 105 106 A P - 0 0 64 0, 0.0 -80,-0.5 0, 0.0 -2,-0.1 -0.139 27.8-108.6 -55.8 143.4 3.5 20.7 -21.8 106 107 A P + 0 0 41 0, 0.0 2,-0.3 0, 0.0 -81,-0.1 -0.342 44.6 178.3 -69.9 157.2 2.2 23.1 -19.1 107 108 A f - 0 0 5 8,-0.1 2,-0.7 -83,-0.0 -83,-0.2 -0.919 36.0 -79.5-152.1 175.0 -0.4 21.8 -16.7 108 109 A E B -n 117 0G 9 8,-2.4 10,-2.2 -2,-0.3 2,-1.0 -0.753 37.4-155.3 -87.9 117.0 -2.5 22.6 -13.7 109 110 A H S S- 0 0 10 -2,-0.7 3,-0.1 111,-0.5 111,-0.1 -0.781 71.5 -40.4 -96.6 97.4 -0.5 22.5 -10.5 110 111 A H S S+ 0 0 104 -2,-1.0 2,-0.3 1,-0.2 -1,-0.2 0.787 122.9 87.4 56.5 32.0 -2.9 21.8 -7.6 111 112 A V S S- 0 0 29 113,-0.1 2,-0.3 2,-0.0 -1,-0.2 -0.955 80.8-106.5-149.6 161.5 -5.5 24.2 -9.0 112 113 A N + 0 0 168 -2,-0.3 2,-0.3 111,-0.1 -3,-0.1 -0.727 55.2 128.5 -93.5 145.8 -8.4 23.9 -11.5 113 114 A G - 0 0 50 -2,-0.3 -5,-0.1 2,-0.3 -2,-0.0 -0.947 68.7 -76.3-171.1-170.1 -8.0 25.4 -14.9 114 115 A S S S+ 0 0 128 -2,-0.3 -2,-0.0 2,-0.1 -6,-0.0 0.625 100.5 82.2 -82.8 -16.1 -8.2 24.9 -18.7 115 116 A R S S- 0 0 49 1,-0.1 -2,-0.3 -8,-0.0 -8,-0.1 -0.469 95.4 -90.2 -86.0 161.1 -4.9 22.9 -18.9 116 117 A P - 0 0 91 0, 0.0 -8,-2.4 0, 0.0 -1,-0.1 -0.353 53.1 -95.8 -67.0 152.2 -4.7 19.2 -18.2 117 118 A P B -n 108 0G 100 0, 0.0 -8,-0.2 0, 0.0 2,-0.1 -0.422 45.5-103.3 -68.7 146.4 -4.0 18.4 -14.5 118 119 A f - 0 0 39 -10,-2.2 2,-0.4 -3,-0.1 -8,-0.1 -0.401 32.2-151.9 -68.8 146.9 -0.3 17.7 -13.8 119 120 A T - 0 0 78 2,-0.1 -1,-0.0 1,-0.1 -10,-0.0 -0.954 16.5-134.3-120.1 139.1 0.7 14.1 -13.3 120 121 A G S S+ 0 0 82 -2,-0.4 2,-0.6 1,-0.1 -93,-0.2 0.801 86.3 84.0 -62.5 -27.5 3.7 13.2 -11.2 121 122 A E + 0 0 182 -95,-0.1 2,-0.3 -3,-0.0 -2,-0.1 -0.687 50.7 138.7 -86.2 116.6 5.0 10.8 -13.9 122 123 A G - 0 0 22 -2,-0.6 -95,-0.3 -52,-0.1 2,-0.3 -0.952 41.1-131.6-154.3 132.5 7.1 12.4 -16.6 123 124 A D - 0 0 149 -2,-0.3 -54,-0.1 -97,-0.1 -98,-0.0 -0.635 29.1-103.3 -91.9 148.2 10.3 11.2 -18.2 124 125 A T - 0 0 56 -2,-0.3 3,-0.1 -56,-0.1 -1,-0.1 -0.474 42.4-124.6 -66.2 125.1 13.4 13.2 -18.7 125 126 A P - 0 0 29 0, 0.0 -1,-0.1 0, 0.0 -55,-0.1 -0.250 35.1 -85.4 -67.6 163.1 13.6 14.2 -22.4 126 127 A K - 0 0 179 1,-0.1 2,-1.1 -65,-0.0 -66,-0.1 -0.280 34.8-115.1 -68.4 152.9 16.7 13.3 -24.5 127 128 A c + 0 0 49 -67,-0.3 2,-0.6 -3,-0.1 -1,-0.1 -0.805 41.5 178.5 -89.7 100.3 19.8 15.5 -24.5 128 129 A S - 0 0 50 -2,-1.1 2,-1.3 2,-0.1 -67,-0.1 -0.939 22.5-154.6-108.0 117.2 19.8 16.7 -28.1 129 130 A K + 0 0 138 -2,-0.6 2,-0.3 2,-0.0 10,-0.2 -0.334 65.4 90.8 -88.7 55.3 22.6 19.0 -29.0 130 131 A T S S- 0 0 83 -2,-1.3 2,-0.2 9,-0.1 -2,-0.1 -0.937 70.8-121.4-141.5 160.0 20.7 20.7 -31.9 131 132 A e - 0 0 28 -2,-0.3 -31,-0.2 1,-0.1 -32,-0.1 -0.653 39.6 -85.9-103.3 162.5 18.4 23.7 -32.2 132 133 A E > - 0 0 43 -33,-2.4 3,-1.7 -34,-0.3 -1,-0.1 -0.224 63.2 -81.5 -60.0 155.0 14.8 23.8 -33.4 133 134 A P T 3 S+ 0 0 129 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.337 116.5 23.8 -62.2 138.6 14.5 24.1 -37.2 134 135 A G T 3 S+ 0 0 85 1,-0.3 2,-0.2 -3,-0.1 -2,-0.1 0.171 94.4 120.5 94.4 -18.6 14.9 27.7 -38.4 135 136 A Y < - 0 0 64 -3,-1.7 -1,-0.3 -36,-0.1 -4,-0.1 -0.583 51.8-128.5 -85.7 144.1 16.9 28.9 -35.4 136 137 A S + 0 0 95 -2,-0.2 2,-0.2 -3,-0.1 -38,-0.1 -0.973 67.1 39.7-138.5 149.4 20.4 30.3 -35.7 137 138 A P S S- 0 0 49 0, 0.0 5,-0.1 0, 0.0 -2,-0.0 0.495 90.3 -94.5 -78.5-166.0 23.2 30.1 -34.6 138 139 A S > - 0 0 55 -2,-0.2 4,-1.4 1,-0.1 5,-0.1 -0.154 38.5-100.6 -66.0 165.9 24.1 26.5 -34.1 139 140 A Y T >4 S+ 0 0 23 1,-0.2 3,-0.6 -10,-0.2 4,-0.3 0.930 124.6 47.7 -53.7 -50.7 23.7 24.7 -30.7 140 141 A K G >4 S+ 0 0 176 1,-0.2 3,-1.1 -11,-0.2 -1,-0.2 0.910 113.0 47.9 -58.7 -44.8 27.4 25.1 -29.9 141 142 A E G 34 S+ 0 0 139 1,-0.2 -1,-0.2 3,-0.0 -2,-0.2 0.669 105.2 60.7 -72.0 -17.0 27.4 28.8 -30.9 142 143 A D G << S+ 0 0 11 -4,-1.4 -1,-0.2 -3,-0.6 -53,-0.2 0.413 77.3 120.8 -91.6 2.3 24.3 29.5 -28.9 143 144 A K < - 0 0 31 -3,-1.1 2,-0.5 -4,-0.3 -55,-0.2 -0.455 46.9-159.5 -71.1 134.8 25.8 28.5 -25.5 144 145 A H B -M 87 0F 59 -57,-2.2 -57,-2.3 -2,-0.2 2,-0.3 -0.974 14.8-150.7-115.1 124.0 26.0 31.1 -22.8 145 146 A F - 0 0 91 -2,-0.5 106,-2.3 -59,-0.2 2,-0.3 -0.708 8.7-142.3-102.8 149.3 28.6 30.4 -20.1 146 147 A G E -B 250 0A 2 -64,-1.8 3,-0.1 -2,-0.3 -60,-0.1 -0.741 5.3-155.9 -98.0 150.9 28.8 31.3 -16.4 147 148 A g E S+ 0 0 89 102,-3.5 2,-0.3 -2,-0.3 -1,-0.1 0.363 74.7 24.2-109.9 4.3 32.2 32.2 -15.0 148 149 A S E -B 249 0A 40 101,-0.9 101,-0.5 -69,-0.1 2,-0.4 -0.960 54.4-168.3-164.1 148.4 31.5 31.3 -11.4 149 150 A S E +B 248 0A 36 -2,-0.3 2,-0.3 99,-0.2 99,-0.3 -0.962 25.7 158.3-142.3 119.7 29.2 29.0 -9.4 150 151 A Y E -B 247 0A 65 97,-2.5 97,-2.3 -2,-0.4 2,-0.5 -0.885 36.8-119.3-141.7 171.2 29.0 29.4 -5.6 151 152 A S E -B 246 0A 86 -2,-0.3 2,-0.3 95,-0.2 95,-0.3 -0.961 23.9-139.3-117.3 126.6 26.9 28.7 -2.5 152 153 A V E -B 245 0A 22 93,-1.8 93,-0.6 -2,-0.5 7,-0.1 -0.660 30.5-105.9 -85.9 137.6 25.6 31.5 -0.3 153 154 A A - 0 0 47 -2,-0.3 2,-2.9 1,-0.2 6,-0.1 -0.129 32.1-100.9 -60.3 155.1 25.7 30.9 3.4 154 155 A N S S+ 0 0 84 89,-0.2 2,-0.4 4,-0.1 -1,-0.2 -0.476 85.1 122.4 -75.5 71.1 22.6 30.2 5.5 155 156 A N > - 0 0 68 -2,-2.9 4,-2.6 87,-0.2 5,-0.2 -0.929 58.8-148.9-143.9 111.8 22.7 33.8 6.6 156 157 A E H > S+ 0 0 37 -2,-0.4 4,-2.5 1,-0.2 5,-0.2 0.871 99.3 46.0 -45.1 -51.5 19.7 36.2 6.0 157 158 A K H > S+ 0 0 116 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.899 112.7 49.0 -64.2 -42.4 21.9 39.3 5.6 158 159 A E H > S+ 0 0 103 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.874 112.5 49.3 -65.9 -35.3 24.4 37.6 3.3 159 160 A I H X S+ 0 0 1 -4,-2.6 4,-2.2 2,-0.2 -2,-0.2 0.929 111.9 47.7 -68.5 -44.5 21.5 36.3 1.1 160 161 A M H X S+ 0 0 11 -4,-2.5 4,-2.9 -5,-0.2 -2,-0.2 0.912 111.9 50.9 -61.5 -42.8 19.9 39.7 1.0 161 162 A A H X S+ 0 0 45 -4,-2.6 4,-2.3 2,-0.2 5,-0.3 0.893 108.6 51.6 -62.2 -41.5 23.2 41.3 0.1 162 163 A E H X S+ 0 0 28 -4,-2.0 4,-3.1 2,-0.2 5,-0.5 0.925 113.8 42.9 -61.6 -47.6 23.8 38.8 -2.7 163 164 A I H X S+ 0 0 0 -4,-2.2 4,-2.2 3,-0.2 -2,-0.2 0.943 112.6 54.3 -63.4 -47.8 20.4 39.5 -4.3 164 165 A Y H < S+ 0 0 117 -4,-2.9 -2,-0.2 -5,-0.2 -1,-0.2 0.870 121.6 28.7 -53.9 -42.5 20.8 43.2 -3.8 165 166 A K H < S+ 0 0 155 -4,-2.3 -2,-0.2 -5,-0.2 -1,-0.2 0.894 135.5 21.5 -89.0 -44.5 24.1 43.3 -5.6 166 167 A N H < S- 0 0 19 -4,-3.1 -3,-0.2 1,-0.3 -2,-0.2 0.474 102.3-113.5-109.3 -3.7 23.9 40.5 -8.1 167 168 A G < - 0 0 0 -4,-2.2 -1,-0.3 -5,-0.5 -2,-0.1 -0.408 60.0 -6.5 103.9 179.4 20.3 39.6 -8.7 168 169 A P - 0 0 0 0, 0.0 2,-0.2 0, 0.0 35,-0.2 -0.077 60.6-159.5 -51.3 147.8 17.9 36.7 -8.0 169 170 A V E -C 202 0A 0 33,-2.0 33,-2.2 78,-0.1 2,-0.4 -0.741 18.6-109.4-123.5 171.1 19.3 33.5 -6.6 170 171 A E E +CD 201 246A 0 76,-2.4 76,-2.5 -2,-0.2 2,-0.3 -0.841 41.5 165.8-103.5 144.2 18.1 29.9 -6.6 171 172 A G E -C 200 0A 0 29,-2.4 29,-2.7 -2,-0.4 2,-0.3 -0.832 19.6-145.7-143.0-179.1 17.0 28.3 -3.3 172 173 A A E +C 199 0A 7 68,-0.3 72,-0.4 69,-0.3 71,-0.3 -0.993 12.5 178.6-153.9 151.0 15.1 25.3 -2.0 173 174 A F E -C 198 0A 8 25,-1.7 25,-1.9 -2,-0.3 2,-0.5 -0.964 38.2 -91.8-149.2 164.0 12.8 24.4 0.8 174 175 A S E -C 197 0A 42 65,-2.7 2,-0.5 -2,-0.3 23,-0.2 -0.685 39.9-143.7 -80.9 125.4 10.8 21.5 2.2 175 176 A V E -C 196 0A 7 21,-2.8 20,-4.0 -2,-0.5 21,-0.9 -0.808 17.1-174.7 -96.2 124.8 7.2 21.4 0.8 176 177 A Y E >> -C 194 0A 59 -2,-0.5 3,-2.2 18,-0.3 4,-0.6 -0.810 41.5-102.3-109.8 155.9 4.4 20.3 3.1 177 178 A S H >> S+ 0 0 37 16,-1.9 3,-0.9 -2,-0.3 4,-0.5 0.747 115.3 66.7 -52.9 -30.0 0.9 19.9 1.8 178 179 A D H 34 S+ 0 0 39 13,-1.3 3,-0.5 1,-0.2 -1,-0.3 0.745 93.9 61.7 -66.4 -17.9 -0.4 23.1 3.2 179 180 A F H X4 S+ 0 0 0 -3,-2.2 3,-2.1 1,-0.2 -1,-0.2 0.831 88.1 71.6 -73.5 -31.3 1.9 25.0 0.8 180 181 A L H << S+ 0 0 24 -3,-0.9 45,-0.2 -4,-0.6 -1,-0.2 0.798 98.8 47.2 -54.9 -32.7 0.1 23.5 -2.2 181 182 A L T 3< S+ 0 0 124 -4,-0.5 -1,-0.3 -3,-0.5 -2,-0.2 0.302 80.0 143.1 -94.5 8.6 -3.0 25.7 -1.6 182 183 A Y < + 0 0 15 -3,-2.1 43,-0.6 1,-0.2 3,-0.1 -0.172 11.0 157.5 -51.0 138.5 -1.1 29.0 -1.1 183 184 A K - 0 0 116 1,-0.5 2,-0.3 41,-0.1 -1,-0.2 0.573 59.3 -22.7-131.4 -39.7 -2.9 32.0 -2.5 184 185 A S S S+ 0 0 88 42,-0.1 -1,-0.5 47,-0.0 2,-0.0 -0.965 89.8 50.4-164.6 176.6 -1.6 35.1 -0.7 185 186 A G S S- 0 0 19 -2,-0.3 2,-0.7 -3,-0.1 46,-0.7 -0.263 95.9 -40.2 79.0-170.1 0.1 36.4 2.4 186 187 A V E -e 231 0A 26 22,-0.1 46,-0.2 44,-0.1 2,-0.1 -0.848 63.9-129.1 -98.2 113.4 3.3 35.2 4.0 187 188 A Y E +e 232 0A 15 44,-3.1 46,-2.1 -2,-0.7 2,-0.4 -0.373 30.7 173.5 -65.5 133.6 3.5 31.4 4.0 188 189 A Q - 0 0 96 44,-0.2 2,-0.2 -2,-0.1 44,-0.0 -0.977 33.3-118.6-141.4 122.8 4.2 29.7 7.3 189 190 A H + 0 0 56 -2,-0.4 3,-0.1 1,-0.2 50,-0.1 -0.451 47.9 147.1 -66.5 126.1 4.1 25.9 7.6 190 191 A V + 0 0 122 1,-0.4 2,-0.3 -2,-0.2 -1,-0.2 0.561 61.9 2.9-130.5 -26.3 1.5 24.6 10.1 191 192 A S S S+ 0 0 78 2,-0.1 -13,-1.3 -15,-0.0 -1,-0.4 -0.979 72.7 79.1-158.3 168.3 0.2 21.3 8.8 192 193 A G - 0 0 28 -2,-0.3 3,-0.1 -15,-0.2 2,-0.0 0.024 68.4 -72.4 107.7 147.2 0.4 18.6 6.1 193 194 A E - 0 0 146 -17,-0.1 -16,-1.9 1,-0.1 2,-0.2 -0.340 59.5 -92.4 -70.5 153.2 2.5 15.6 5.1 194 195 A I E -C 176 0A 108 -18,-0.2 -18,-0.3 1,-0.1 -1,-0.1 -0.475 35.9-174.4 -68.4 133.4 6.0 16.2 3.6 195 196 A M E - 0 0 82 -20,-4.0 2,-0.2 1,-0.4 -19,-0.2 0.592 46.5-102.7-103.0 -18.1 5.9 16.4 -0.2 196 197 A G E -C 175 0A 29 -21,-0.9 -21,-2.8 2,-0.0 -1,-0.4 -0.638 52.9 -37.2 121.5 179.6 9.7 16.6 -0.7 197 198 A G E -C 174 0A 68 -23,-0.2 2,-0.4 -2,-0.2 -23,-0.2 -0.443 50.6-163.8 -77.5 152.8 12.2 19.3 -1.5 198 199 A H E -C 173 0A 13 -25,-1.9 -25,-1.7 -2,-0.1 2,-0.3 -0.946 8.5-147.3-143.9 119.1 11.4 22.1 -4.0 199 200 A A E +C 172 0A 5 -2,-0.4 -27,-0.3 -27,-0.2 2,-0.2 -0.649 28.9 162.6 -86.0 139.9 13.8 24.4 -5.7 200 201 A I E -C 171 0A 2 -29,-2.7 -29,-2.4 -2,-0.3 2,-0.5 -0.791 38.5 -98.6-143.1-176.5 12.7 28.0 -6.5 201 202 A R E -CF 170 217A 1 16,-1.7 16,-3.0 -2,-0.2 2,-0.6 -0.959 24.6-156.5-117.2 120.0 13.9 31.5 -7.4 202 203 A I E +CF 169 216A 0 -33,-2.2 -33,-2.0 -2,-0.5 14,-0.2 -0.859 20.7 165.4 -97.7 118.2 14.2 34.1 -4.7 203 204 A L E - 0 0 0 12,-2.2 -196,-2.5 -2,-0.6 2,-0.3 0.210 57.0 -30.4-118.2 14.3 14.0 37.6 -6.2 204 205 A G E -AF 6 215A 0 11,-0.7 11,-2.5 -198,-0.2 2,-0.3 -0.994 51.5-123.1 165.0-168.6 13.5 39.9 -3.2 205 206 A W E +AF 5 214A 4 -200,-2.2 -200,-2.7 -2,-0.3 2,-0.3 -0.973 23.5 153.9-161.7 168.4 12.1 40.5 0.3 206 207 A G E - F 0 213A 0 7,-1.8 7,-2.7 -2,-0.3 2,-0.4 -0.942 38.8 -93.0-175.2-166.6 9.8 42.7 2.3 207 208 A V E - F 0 212A 51 -2,-0.3 2,-0.5 5,-0.2 -2,-0.0 -0.997 27.0-170.8-136.1 127.6 7.6 42.9 5.4 208 209 A E E > S- F 0 211A 56 3,-2.6 3,-1.9 -2,-0.4 -22,-0.1 -0.970 75.9 -20.9-124.2 117.7 3.9 42.1 5.4 209 210 A N T 3 S- 0 0 155 -2,-0.5 -1,-0.1 1,-0.3 0, 0.0 0.871 129.7 -49.6 54.8 39.3 1.8 42.9 8.5 210 211 A G T 3 S+ 0 0 67 1,-0.2 -1,-0.3 -3,-0.0 -3,-0.0 0.464 114.8 120.1 81.3 1.4 5.0 42.8 10.6 211 212 A T E < -F 208 0A 38 -3,-1.9 -3,-2.6 22,-0.0 -1,-0.2 -0.884 59.4-137.3-105.4 115.7 6.1 39.5 9.1 212 213 A P E +F 207 0A 43 0, 0.0 22,-2.2 0, 0.0 2,-0.3 -0.435 33.6 175.7 -68.6 140.3 9.5 39.5 7.2 213 214 A Y E -FG 206 233A 29 -7,-2.7 -7,-1.8 20,-0.3 2,-0.4 -0.934 33.5-122.3-145.6 167.1 9.4 37.5 4.0 214 215 A W E -FG 205 232A 0 18,-2.2 18,-1.4 -2,-0.3 2,-0.7 -0.891 28.0-131.2-107.5 138.4 11.2 36.3 0.9 215 216 A L E -FG 204 231A 14 -11,-2.5 -12,-2.2 -2,-0.4 -11,-0.7 -0.843 36.6-173.7 -91.7 118.9 9.6 37.2 -2.5 216 217 A V E -FG 202 230A 0 14,-2.8 14,-2.2 -2,-0.7 2,-0.6 -0.930 25.4-147.8-126.1 140.9 9.7 33.9 -4.5 217 218 A G E -FG 201 229A 1 -16,-3.0 -16,-1.7 -2,-0.4 12,-0.2 -0.898 20.2-159.5-103.1 122.8 8.9 32.8 -8.0 218 219 A N - 0 0 0 10,-2.2 -197,-0.4 -2,-0.6 3,-0.2 -0.496 19.3-131.7 -93.9 168.2 7.5 29.3 -8.4 219 220 A S S S+ 0 0 2 -20,-0.2 -196,-2.5 -2,-0.2 -195,-0.3 -0.202 78.7 100.0-114.2 41.1 7.5 27.2 -11.5 220 221 A W B S-I 22 0B 20 1,-0.4 -111,-0.5 8,-0.3 -198,-0.2 -0.104 91.6-100.6-115.6 32.9 3.9 26.1 -11.5 221 222 A N > - 0 0 28 -200,-2.2 3,-0.7 1,-0.2 -1,-0.4 0.064 45.1 -70.8 71.2 175.5 2.5 28.6 -14.0 222 223 A T T 3 S+ 0 0 74 1,-0.2 5,-0.3 -202,-0.2 6,-0.2 0.587 120.6 65.5 -82.0 -13.2 0.6 31.8 -13.3 223 224 A D T 3 S+ 0 0 53 -3,-0.2 2,-0.4 4,-0.2 -1,-0.2 0.429 87.4 82.9 -91.2 4.0 -2.7 30.4 -12.0 224 225 A W S <> S- 0 0 0 -3,-0.7 4,-1.9 -4,-0.2 -6,-0.1 -0.838 102.2 -24.4-102.6 144.3 -1.1 28.8 -9.0 225 226 A G T 4 S- 0 0 13 -43,-0.6 2,-1.2 -2,-0.4 5,-0.2 -0.222 124.7 -11.5 59.5-141.6 -0.5 31.0 -5.9 226 227 A D B >4 S-H 229 0A 64 3,-2.5 3,-2.1 1,-0.2 -1,-0.2 -0.703 128.5 -48.6 -96.4 82.1 -0.2 34.7 -6.3 227 228 A N T 34 S- 0 0 113 -2,-1.2 -1,-0.2 1,-0.3 -4,-0.2 0.806 115.7 -48.2 59.4 29.3 0.2 35.0 -10.1 228 229 A G T 3< S+ 0 0 0 -4,-1.9 -10,-2.2 1,-0.4 -8,-0.3 0.217 125.7 95.6 97.4 -15.5 2.8 32.3 -9.8 229 230 A F E < -HG 226 217A 15 -3,-2.1 -3,-2.5 -12,-0.2 -1,-0.4 -0.522 48.9-175.3-101.9 170.8 4.7 33.9 -7.0 230 231 A F E - G 0 216A 1 -14,-2.2 -14,-2.8 -2,-0.2 2,-0.4 -0.976 19.7-130.6-159.4 161.7 4.5 33.5 -3.2 231 232 A K E -eG 186 215A 41 -46,-0.7 -44,-3.1 -2,-0.3 2,-0.3 -0.951 22.9-171.2-119.0 141.1 6.0 34.9 -0.0 232 233 A I E -eG 187 214A 1 -18,-1.4 -18,-2.2 -2,-0.4 -44,-0.2 -0.974 37.3 -81.9-134.3 147.4 7.5 32.8 2.7 233 234 A L E - G 0 213A 17 -46,-2.1 2,-0.3 -2,-0.3 5,-0.3 -0.159 48.2-152.7 -47.6 132.1 8.7 33.6 6.2 234 235 A R + 0 0 14 -22,-2.2 -1,-0.1 1,-0.1 -29,-0.0 -0.866 63.2 30.1-113.9 144.9 12.2 35.1 6.3 235 236 A G S S+ 0 0 24 -2,-0.3 -1,-0.1 3,-0.1 -79,-0.1 0.305 101.0 72.4 98.3 -9.1 14.9 35.0 9.0 236 237 A Q S S- 0 0 148 -3,-0.1 3,-0.2 -80,-0.0 4,-0.2 0.184 102.0-114.8-121.3 14.8 14.1 31.6 10.7 237 238 A D > - 0 0 52 1,-0.2 3,-2.4 2,-0.1 2,-0.2 0.897 47.0-161.4 48.9 42.3 15.4 29.3 7.9 238 239 A H G > - 0 0 35 -5,-0.3 3,-2.0 1,-0.3 -1,-0.2 -0.354 68.6 -9.8 -60.4 123.0 11.8 28.3 7.7 239 240 A C G 3 S- 0 0 22 1,-0.3 -65,-2.7 -3,-0.2 -1,-0.3 0.697 126.5 -68.8 58.7 18.7 11.4 25.0 5.9 240 241 A G G X S+ 0 0 14 -3,-2.4 3,-1.7 -67,-0.2 4,-0.5 0.669 89.9 148.9 76.2 19.1 15.1 25.4 5.1 241 242 A I T < S+ 0 0 1 -3,-2.0 -69,-0.3 1,-0.3 3,-0.2 0.744 77.3 39.6 -57.0 -25.5 14.4 28.4 2.7 242 243 A E T 3 S+ 0 0 6 1,-0.1 3,-0.4 -71,-0.1 -1,-0.3 0.408 99.6 79.7-104.0 2.2 17.8 29.9 3.6 243 244 A S S < S+ 0 0 66 -3,-1.7 -2,-0.2 -71,-0.3 -89,-0.2 0.584 95.6 35.8 -88.7 -10.9 19.8 26.6 3.8 244 245 A E S S+ 0 0 85 -4,-0.5 2,-0.4 -72,-0.4 -1,-0.2 -0.260 71.8 154.7-139.3 50.5 20.4 25.9 0.1 245 246 A I E +B 152 0A 2 -93,-0.6 -93,-1.8 -3,-0.4 2,-0.3 -0.662 14.9 172.3 -83.7 129.8 21.0 29.2 -1.7 246 247 A V E +BD 151 170A 4 -76,-2.5 -76,-2.4 -2,-0.4 2,-0.3 -0.969 6.3 145.3-137.3 152.9 23.1 29.0 -4.8 247 248 A A E -B 150 0A 0 -97,-2.3 -97,-2.5 -2,-0.3 2,-0.3 -0.871 16.5-167.0-162.4-167.0 24.1 31.4 -7.6 248 249 A G E -B 149 0A 0 -99,-0.3 -99,-0.2 -2,-0.3 -207,-0.0 -0.947 24.2-104.1 176.8 169.8 26.9 32.4 -9.9 249 250 A M E -B 148 0A 49 -101,-0.5 -102,-3.5 -2,-0.3 -101,-0.9 -0.921 30.6-120.0-118.0 139.4 28.0 35.2 -12.3 250 251 A P E -B 146 0A 18 0, 0.0 -104,-0.3 0, 0.0 2,-0.2 -0.349 37.4 -97.7 -72.9 156.0 28.0 35.1 -16.1 251 252 A g 0 0 42 -106,-2.3 -106,-0.1 1,-0.1 -206,-0.0 -0.514 360.0 360.0 -70.8 143.8 31.1 35.4 -18.1 252 253 A T 0 0 178 -2,-0.2 -1,-0.1 -3,-0.1 -106,-0.0 0.599 360.0 360.0 -11.2 360.0 31.7 39.0 -19.3