==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=19-JAN-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 12-JUN-08 3DFJ . COMPND 2 MOLECULE: PROSTASIN; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR H.P.SU,K.W.RICKERT,P.L.DARKE,S.K.MUNSHI . 248 1 4 4 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11911.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 150 60.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 73 29.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 2.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 16 6.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 29 11.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 14 5.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 3 4 1 4 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 45 A I 0 0 1 0, 0.0 2,-0.4 0, 0.0 3,-0.3 0.000 360.0 360.0 360.0 123.1 -23.4 5.3 2.6 2 46 A T B +A 188 0A 18 186,-2.9 186,-1.2 1,-0.2 131,-0.1 -0.860 360.0 11.9-103.1 138.2 -25.5 7.7 0.5 3 47 A G S S+ 0 0 47 129,-0.5 -1,-0.2 -2,-0.4 184,-0.1 0.631 103.2 108.7 77.0 14.5 -28.2 6.5 -1.9 4 48 A G - 0 0 32 -3,-0.3 2,-0.3 184,-0.1 143,-0.2 -0.024 62.7-113.1 -99.7-154.1 -28.1 3.0 -0.6 5 49 A S E -B 146 0B 58 141,-2.3 141,-2.8 -3,-0.1 2,-0.4 -0.929 32.7 -88.8-139.9 161.7 -30.5 0.8 1.4 6 50 A S E -B 145 0B 63 -2,-0.3 139,-0.2 139,-0.2 138,-0.1 -0.618 42.8-136.1 -71.1 128.9 -30.6 -0.8 4.8 7 51 A A - 0 0 5 137,-2.8 2,-0.3 -2,-0.4 -1,-0.1 -0.229 23.5-105.3 -68.8 170.9 -29.1 -4.3 4.7 8 52 A V > - 0 0 103 1,-0.1 3,-2.2 135,-0.1 4,-0.3 -0.761 50.0 -81.1 -96.1 150.4 -30.8 -7.1 6.6 9 53 A A T 3 S+ 0 0 50 -2,-0.3 50,-0.1 1,-0.3 -1,-0.1 -0.255 115.6 8.6 -53.1 130.2 -29.3 -8.4 9.8 10 54 A G T 3 S+ 0 0 29 48,-0.2 -1,-0.3 95,-0.1 49,-0.1 0.437 90.2 120.4 81.3 1.9 -26.4 -10.8 9.2 11 55 A Q S < S+ 0 0 86 -3,-2.2 -2,-0.1 1,-0.3 3,-0.1 0.802 84.8 30.3 -68.9 -30.4 -26.3 -10.2 5.5 12 56 A W S > S+ 0 0 15 -4,-0.3 3,-2.1 1,-0.1 -1,-0.3 -0.666 74.2 172.5-127.9 71.3 -22.7 -8.9 5.6 13 57 A P T 3 S+ 0 0 19 0, 0.0 94,-1.3 0, 0.0 44,-0.3 0.519 73.1 59.4 -73.4 -3.7 -21.3 -10.9 8.5 14 58 A W T 3 S+ 0 0 25 92,-0.2 16,-2.4 94,-0.1 2,-0.3 0.568 79.6 109.4 -89.4 -13.7 -17.7 -9.8 7.9 15 59 A Q E < +J 29 0C 3 -3,-2.1 42,-0.5 14,-0.2 43,-0.4 -0.473 47.7 180.0 -69.8 127.1 -18.6 -6.1 8.3 16 60 A V E -J 28 0C 1 12,-2.3 12,-1.2 -2,-0.3 2,-0.5 -0.882 25.4-130.7-123.4 158.1 -17.3 -4.6 11.6 17 61 A S E -JK 27 55C 3 38,-2.1 38,-3.0 -2,-0.3 2,-0.5 -0.930 18.7-155.2-104.3 131.8 -17.4 -1.2 13.2 18 62 A I E -JK 26 54C 0 8,-2.9 7,-3.0 -2,-0.5 8,-1.7 -0.945 13.4-169.8-110.4 124.0 -14.1 0.3 14.4 19 63 A T E -JK 24 53C 18 34,-2.5 34,-1.8 -2,-0.5 2,-0.4 -0.826 15.5-157.6-112.1 151.1 -14.3 2.8 17.3 20 64 A Y E > S-JK 23 52C 43 3,-2.4 3,-1.7 -2,-0.3 32,-0.2 -0.996 86.6 -11.9-125.5 123.9 -11.7 5.1 18.8 21 65 A E T 3 S- 0 0 147 30,-2.6 31,-0.1 -2,-0.4 -1,-0.1 0.879 133.3 -52.7 48.8 42.6 -12.5 6.3 22.3 22 66 A G T 3 S+ 0 0 61 29,-0.5 2,-0.5 1,-0.2 -1,-0.3 0.341 115.5 111.5 85.2 -5.3 -16.0 4.9 21.9 23 67 A V E < S-J 20 0C 96 -3,-1.7 -3,-2.4 1,-0.0 2,-0.2 -0.889 72.9-115.3-108.7 128.2 -16.8 6.7 18.7 24 68 A H E +J 19 0C 44 -2,-0.5 -5,-0.3 -5,-0.3 3,-0.1 -0.415 44.6 158.8 -58.8 123.6 -17.3 4.9 15.3 25 69 A V E + 0 0 56 -7,-3.0 167,-0.3 1,-0.3 2,-0.3 0.662 57.0 0.5-117.2 -31.7 -14.5 6.1 13.0 26 70 A a E -J 18 0C 6 -8,-1.7 -8,-2.9 167,-0.1 -1,-0.3 -0.955 60.2-117.3-153.1 165.1 -14.1 3.4 10.3 27 71 A G E +J 17 0C 0 167,-3.0 12,-0.4 -2,-0.3 2,-0.3 -0.507 29.5 179.1 -96.1 175.1 -15.4 0.1 8.9 28 72 A G E -J 16 0C 0 -12,-1.2 -12,-2.3 -2,-0.2 2,-0.4 -0.956 22.6-118.8-163.4 175.0 -13.4 -3.1 8.6 29 73 A S E -JL 15 37C 0 8,-2.5 8,-3.0 -2,-0.3 2,-0.3 -0.992 19.1-129.4-130.6 127.7 -13.7 -6.8 7.5 30 74 A L E + L 0 36C 1 -16,-2.4 79,-2.3 -2,-0.4 6,-0.2 -0.570 31.8 167.4 -69.3 129.7 -13.3 -9.9 9.5 31 75 A V - 0 0 19 4,-2.6 2,-0.3 -2,-0.3 5,-0.2 0.517 61.7 -4.3-123.5 -12.3 -10.9 -12.2 7.6 32 76 A S S S- 0 0 24 3,-1.3 -1,-0.3 75,-0.1 68,-0.1 -0.928 89.3 -74.3-162.8-176.2 -10.0 -14.9 10.2 33 77 A E S S+ 0 0 76 -2,-0.3 67,-2.7 1,-0.2 65,-0.1 0.774 130.0 17.0 -62.5 -25.6 -10.6 -15.8 13.9 34 78 A Q S S+ 0 0 6 65,-0.2 62,-2.6 1,-0.0 2,-0.4 0.376 111.0 83.5-128.2 3.2 -8.2 -13.0 15.1 35 79 A W E - M 0 95C 1 60,-0.2 -4,-2.6 -3,-0.1 -3,-1.3 -0.937 43.1-177.2-122.8 136.1 -7.7 -10.7 12.1 36 80 A V E -LM 30 94C 0 58,-2.2 58,-3.0 -2,-0.4 2,-0.5 -0.968 17.7-144.3-120.1 137.8 -9.6 -7.7 10.7 37 81 A L E +LM 29 93C 0 -8,-3.0 -8,-2.5 -2,-0.4 2,-0.2 -0.908 34.7 144.0-100.9 131.2 -8.6 -5.8 7.6 38 82 A S E - M 0 92C 0 54,-2.4 54,-2.4 -2,-0.5 2,-0.4 -0.674 51.3 -68.8-141.7-164.1 -9.2 -2.1 7.4 39 83 A A > - 0 0 0 -12,-0.4 3,-1.5 52,-0.3 52,-0.2 -0.812 28.1-136.2-100.5 140.6 -7.5 1.0 6.0 40 84 A A G > S+ 0 0 3 -2,-0.4 3,-2.1 1,-0.3 -1,-0.1 0.815 101.9 67.9 -60.2 -31.9 -4.2 2.3 7.2 41 85 A H G 3 S+ 0 0 59 1,-0.3 -1,-0.3 43,-0.1 44,-0.1 0.700 90.7 64.5 -64.2 -17.5 -5.5 5.9 7.1 42 86 A a G < S+ 0 0 11 -3,-1.5 -1,-0.3 1,-0.2 -2,-0.2 0.551 98.3 58.7 -78.0 -8.6 -7.8 5.0 10.0 43 87 A F < - 0 0 14 -3,-2.1 -1,-0.2 -4,-0.2 6,-0.0 -0.627 67.4-169.7-131.8 73.8 -4.9 4.4 12.4 44 88 A P > - 0 0 43 0, 0.0 3,-1.5 0, 0.0 -3,-0.0 -0.346 31.3-123.3 -60.8 142.9 -2.6 7.3 13.0 45 89 A S T 3 S+ 0 0 121 1,-0.3 -2,-0.0 3,-0.0 0, 0.0 0.715 107.6 64.1 -65.6 -22.2 0.6 6.2 14.9 46 90 A E T 3 S+ 0 0 137 2,-0.1 -1,-0.3 0, 0.0 2,-0.1 0.691 83.9 94.9 -74.2 -20.7 -0.1 8.8 17.7 47 91 A H S < S- 0 0 61 -3,-1.5 2,-0.4 1,-0.1 5,-0.0 -0.466 81.7-117.0 -72.0 143.1 -3.3 7.0 18.6 48 92 A H > - 0 0 113 -2,-0.1 3,-1.9 1,-0.1 4,-0.3 -0.710 9.6-139.0 -87.2 131.5 -3.1 4.4 21.4 49 93 A K G > S+ 0 0 84 -2,-0.4 3,-1.6 1,-0.3 24,-0.4 0.842 101.2 61.0 -51.6 -40.8 -4.0 0.8 20.6 50 94 A E G 3 S+ 0 0 139 1,-0.3 -1,-0.3 22,-0.1 24,-0.0 0.538 93.4 65.4 -72.4 -6.0 -5.9 0.4 23.8 51 95 A A G < S+ 0 0 25 -3,-1.9 -30,-2.6 -30,-0.1 -29,-0.5 0.519 88.6 87.6 -91.8 -6.8 -8.4 3.2 22.8 52 96 A Y E < -K 20 0C 2 -3,-1.6 21,-0.4 -4,-0.3 2,-0.3 -0.622 52.7-174.7 -92.5 150.6 -9.8 1.2 19.9 53 97 A E E -K 19 0C 83 -34,-1.8 -34,-2.5 -2,-0.2 2,-0.4 -0.974 14.8-147.5-135.8 157.5 -12.6 -1.3 19.7 54 98 A V E -KN 18 71C 0 17,-2.5 17,-2.6 -2,-0.3 2,-0.6 -0.994 10.2-157.9-121.4 124.1 -14.0 -3.6 17.0 55 99 A K E -KN 17 70C 48 -38,-3.0 -38,-2.1 -2,-0.4 2,-0.3 -0.930 16.0-174.5-106.3 119.7 -17.7 -4.4 17.0 56 100 A L E + N 0 69C 1 13,-3.2 13,-2.4 -2,-0.6 -40,-0.1 -0.746 58.2 25.5-111.9 155.3 -18.7 -7.6 15.2 57 101 A G S S+ 0 0 8 -42,-0.5 2,-0.3 48,-0.3 -1,-0.2 0.687 85.6 143.0 69.5 21.6 -22.0 -9.2 14.3 58 102 A A + 0 0 15 -43,-0.4 -1,-0.2 -3,-0.3 -48,-0.2 -0.665 27.1 164.7 -97.4 146.5 -23.9 -5.9 14.4 59 103 A H S S+ 0 0 36 1,-0.4 85,-1.3 -2,-0.3 2,-0.7 0.619 82.2 29.9-114.5 -65.9 -26.7 -4.6 12.3 60 104 A Q B > S-P 143 0D 74 83,-0.2 3,-1.3 1,-0.1 -1,-0.4 -0.891 75.8-154.4 -95.5 112.3 -28.1 -1.6 14.1 61 105 A L T 3 S+ 0 0 19 81,-2.0 81,-0.2 -2,-0.7 -1,-0.1 0.845 90.9 45.5 -56.8 -39.2 -25.2 -0.1 16.0 62 106 A D T 3 S+ 0 0 88 79,-2.0 2,-0.3 -3,-0.1 -1,-0.3 0.484 97.6 88.4 -87.8 -4.1 -27.3 1.5 18.8 63 107 A S S < S- 0 0 45 -3,-1.3 2,-0.3 78,-0.5 -4,-0.1 -0.722 82.4-115.2 -93.4 143.7 -29.5 -1.6 19.3 64 108 A Y + 0 0 192 -2,-0.3 2,-0.4 -6,-0.1 -2,-0.1 -0.615 37.1 178.6 -75.8 136.1 -28.6 -4.3 21.8 65 109 A S > - 0 0 38 -2,-0.3 3,-0.6 1,-0.1 -2,-0.0 -0.989 32.7-152.9-139.7 130.7 -28.0 -7.7 20.2 66 110 A E T 3 S+ 0 0 151 -2,-0.4 -1,-0.1 1,-0.2 -2,-0.0 0.639 101.5 60.4 -69.4 -13.9 -26.9 -10.9 21.9 67 111 A D T 3 S+ 0 0 66 -10,-0.1 -1,-0.2 2,-0.0 2,-0.1 0.693 87.6 88.3 -87.6 -22.7 -25.3 -11.8 18.5 68 112 A A < - 0 0 18 -3,-0.6 2,-0.3 -13,-0.0 -11,-0.2 -0.431 58.3-166.5 -77.2 152.3 -22.9 -8.8 18.5 69 113 A K E -N 56 0C 102 -13,-2.4 -13,-3.2 -2,-0.1 2,-0.4 -0.996 8.0-149.7-140.1 141.8 -19.5 -9.0 20.1 70 114 A V E +N 55 0C 80 -2,-0.3 2,-0.3 -15,-0.2 -15,-0.2 -0.947 18.1 180.0-117.6 136.2 -17.0 -6.3 21.0 71 115 A S E -N 54 0C 18 -17,-2.6 -17,-2.5 -2,-0.4 2,-0.2 -0.897 19.8-140.4-128.4 156.1 -13.2 -6.8 21.1 72 116 A T - 0 0 59 -2,-0.3 25,-2.5 -19,-0.2 2,-0.4 -0.519 33.4-105.0-100.2-179.5 -10.1 -4.7 21.8 73 117 A L E -O 96 0C 7 -21,-0.4 23,-0.3 -24,-0.4 3,-0.1 -0.912 20.8-170.9-117.4 137.4 -6.9 -5.0 19.7 74 118 A K E S+ 0 0 118 21,-3.0 2,-0.3 -2,-0.4 22,-0.2 0.734 81.6 5.8 -86.6 -31.3 -3.5 -6.7 20.5 75 119 A D E -O 95 0C 62 20,-1.4 20,-2.5 -26,-0.1 2,-0.4 -0.995 52.3-155.1-153.9 150.4 -1.9 -5.1 17.5 76 120 A I E -O 94 0C 32 -2,-0.3 18,-0.2 18,-0.2 -27,-0.1 -0.990 18.4-175.7-127.0 118.2 -2.4 -2.6 14.6 77 121 A I E -O 93 0C 24 16,-3.1 16,-2.5 -2,-0.4 2,-0.1 -0.818 3.8-170.4-122.7 90.5 -0.2 -3.3 11.6 78 122 A P E -O 92 0C 53 0, 0.0 14,-0.3 0, 0.0 12,-0.1 -0.486 45.6 -89.1 -71.0 150.2 -0.5 -0.8 8.7 79 123 A H > - 0 0 34 12,-2.5 3,-2.0 10,-0.5 12,-0.1 -0.397 35.9-126.1 -58.9 134.9 1.3 -1.9 5.6 80 124 A P T 3 S+ 0 0 103 0, 0.0 -1,-0.2 0, 0.0 9,-0.0 0.747 106.8 62.6 -56.8 -24.2 4.9 -0.7 5.8 81 125 A S T 3 S+ 0 0 53 8,-0.1 2,-0.3 6,-0.0 7,-0.2 0.621 77.6 108.3 -77.2 -13.7 4.6 1.1 2.4 82 126 A Y < + 0 0 43 -3,-2.0 7,-0.1 7,-0.3 3,-0.1 -0.511 36.5 155.8 -71.5 125.1 1.9 3.4 3.7 83 127 A L - 0 0 139 1,-0.5 2,-0.1 5,-0.4 -1,-0.1 0.574 52.3 -10.0-111.0-100.1 3.1 7.0 4.1 84 128 A Q S > S- 0 0 163 1,-0.2 3,-2.1 4,-0.0 -1,-0.5 -0.440 92.7 -60.6 -97.8 173.9 0.8 10.0 4.0 85 129 A E T 3 S+ 0 0 155 1,-0.2 -1,-0.2 -2,-0.1 3,-0.1 -0.291 125.8 25.8 -49.8 132.7 -2.9 10.3 3.0 86 130 A G T 3 S+ 0 0 40 1,-0.3 -1,-0.2 127,-0.1 88,-0.1 0.280 93.6 127.3 93.0 -10.4 -3.3 9.2 -0.6 87 131 A S < - 0 0 19 -3,-2.1 3,-0.3 1,-0.1 -1,-0.3 -0.344 66.3 -94.4 -80.0 161.7 -0.3 6.9 -0.7 88 132 A Q S S+ 0 0 76 1,-0.2 -5,-0.4 -7,-0.2 -1,-0.1 -0.177 102.5 51.7 -61.5 162.1 -0.2 3.3 -1.8 89 133 A G + 0 0 0 1,-0.2 2,-2.3 -7,-0.1 -10,-0.5 0.733 59.9 163.2 79.6 23.4 -0.5 0.6 0.9 90 134 A D + 0 0 2 -3,-0.3 2,-0.3 -51,-0.1 138,-0.2 -0.472 40.9 101.9 -76.2 76.7 -3.7 2.0 2.5 91 135 A I - 0 0 0 -2,-2.3 -12,-2.5 -52,-0.2 2,-0.4 -0.978 48.6-167.1-158.0 144.2 -4.4 -1.3 4.3 92 136 A A E -MO 38 78C 0 -54,-2.4 -54,-2.4 -2,-0.3 2,-0.5 -0.997 16.3-141.1-144.0 138.1 -4.0 -2.5 7.9 93 137 A L E -MO 37 77C 0 -16,-2.5 -16,-3.1 -2,-0.4 2,-0.5 -0.862 19.2-160.9 -93.8 126.5 -4.2 -5.7 9.7 94 138 A L E -MO 36 76C 0 -58,-3.0 -58,-2.2 -2,-0.5 2,-0.7 -0.950 5.3-151.0-111.8 122.3 -5.8 -5.5 13.1 95 139 A Q E -MO 35 75C 8 -20,-2.5 -21,-3.0 -2,-0.5 -20,-1.4 -0.843 17.0-133.1 -96.5 116.5 -5.1 -8.3 15.6 96 140 A L E - O 0 73C 1 -62,-2.6 -23,-0.3 -2,-0.7 -43,-0.0 -0.354 19.2-118.8 -65.5 147.6 -8.0 -8.9 18.0 97 141 A S S S+ 0 0 40 -25,-2.5 -24,-0.1 1,-0.1 -1,-0.1 0.825 99.4 7.5 -56.8 -35.8 -7.0 -9.2 21.7 98 142 A R S S- 0 0 201 -26,-0.3 -1,-0.1 -65,-0.1 2,-0.1 -0.969 94.2 -94.5-140.9 153.5 -8.5 -12.7 21.6 99 143 A P - 0 0 55 0, 0.0 -65,-0.2 0, 0.0 2,-0.2 -0.420 40.3-135.8 -68.8 144.7 -9.8 -14.9 18.8 100 144 A I - 0 0 20 -67,-2.7 2,-0.5 -68,-0.1 -4,-0.0 -0.555 13.6-116.1 -93.7 164.8 -13.6 -14.7 18.3 101 145 A T - 0 0 125 -2,-0.2 2,-0.0 6,-0.0 5,-0.0 -0.900 31.2-121.3-101.2 129.2 -15.9 -17.6 17.6 102 146 A F + 0 0 74 -2,-0.5 2,-0.3 3,-0.1 5,-0.2 -0.359 38.1 167.3 -67.5 147.9 -17.7 -17.6 14.2 103 147 A S - 0 0 39 3,-2.1 3,-0.5 -90,-0.1 -46,-0.1 -0.824 56.1 -84.4-144.0-178.3 -21.5 -17.6 14.2 104 148 A R S S+ 0 0 223 -2,-0.3 3,-0.1 1,-0.2 -2,-0.0 0.743 133.9 41.6 -64.7 -22.2 -24.2 -17.0 11.5 105 149 A Y S S+ 0 0 82 1,-0.2 2,-0.4 -38,-0.1 -48,-0.3 0.530 114.7 52.8 -99.2 -12.7 -23.7 -13.3 12.3 106 150 A I S S+ 0 0 2 -3,-0.5 -3,-2.1 -50,-0.1 -1,-0.2 -0.894 70.3 144.1-131.8 99.0 -19.9 -13.3 12.5 107 151 A R - 0 0 112 -94,-1.3 -77,-0.2 -2,-0.4 2,-0.1 -0.987 45.0-114.5-138.3 143.0 -18.1 -14.8 9.5 108 152 A P - 0 0 43 0, 0.0 2,-0.4 0, 0.0 -77,-0.3 -0.462 26.2-126.2 -75.5 149.5 -14.9 -14.1 7.6 109 153 A I - 0 0 4 -79,-2.3 2,-0.1 -2,-0.1 98,-0.1 -0.791 30.5-107.8 -91.5 139.7 -14.9 -12.9 4.0 110 154 A S B -c 207 0B 63 96,-0.8 98,-2.4 -2,-0.4 -1,-0.0 -0.434 32.0-132.7 -65.8 137.0 -12.8 -14.8 1.5 111 155 A L - 0 0 58 96,-0.2 2,-0.1 -80,-0.1 98,-0.1 -0.728 18.4-117.6 -93.6 140.4 -9.6 -13.0 0.4 112 156 A P - 0 0 6 0, 0.0 -1,-0.0 0, 0.0 122,-0.0 -0.468 28.7-111.4 -74.5 147.9 -8.7 -12.8 -3.3 113 157 A A > - 0 0 65 -2,-0.1 3,-1.5 1,-0.1 120,-0.1 -0.268 34.8-102.5 -64.7 162.4 -5.5 -14.3 -4.6 114 158 A A T 3 S+ 0 0 58 1,-0.3 -1,-0.1 118,-0.1 117,-0.0 0.848 125.0 42.4 -53.8 -36.6 -2.7 -12.0 -5.8 115 159 A N T 3 S+ 0 0 158 2,-0.1 2,-0.3 117,-0.0 -1,-0.3 0.263 82.7 126.3-100.4 9.2 -3.7 -12.8 -9.4 116 160 A A < - 0 0 34 -3,-1.5 2,-0.4 115,-0.1 115,-0.1 -0.548 44.9-158.6 -68.2 127.2 -7.5 -12.6 -8.9 117 161 A S - 0 0 106 -2,-0.3 -2,-0.1 114,-0.0 -4,-0.1 -0.893 11.2-162.1-109.4 141.6 -9.0 -10.2 -11.4 118 162 A F - 0 0 28 -2,-0.4 3,-0.1 91,-0.1 2,-0.0 -0.992 28.0-125.2-122.4 119.6 -12.3 -8.5 -11.0 119 163 A P > - 0 0 79 0, 0.0 3,-2.1 0, 0.0 32,-0.3 -0.303 25.9 -93.7 -74.6 147.5 -13.6 -7.1 -14.3 120 164 A N T 3 S+ 0 0 118 1,-0.3 32,-0.2 30,-0.1 3,-0.1 -0.246 112.6 26.4 -47.3 135.4 -14.7 -3.6 -15.0 121 165 A G T 3 S+ 0 0 39 30,-2.3 -1,-0.3 1,-0.3 31,-0.1 0.274 79.8 147.5 90.1 -10.7 -18.5 -3.3 -14.5 122 166 A L < - 0 0 39 -3,-2.1 29,-1.7 28,-0.1 2,-1.2 -0.371 52.6-122.7 -59.7 134.6 -18.9 -6.1 -12.0 123 167 A H E +D 150 0B 104 27,-0.2 2,-0.1 78,-0.1 -1,-0.1 -0.693 44.8 166.3 -86.3 96.6 -21.7 -5.2 -9.6 124 168 A b E -D 149 0B 0 25,-2.3 25,-3.0 -2,-1.2 2,-0.4 -0.436 29.0-121.0-100.6 176.9 -20.1 -5.3 -6.1 125 169 A T E -DE 148 199B 16 74,-2.6 74,-2.9 23,-0.2 2,-0.4 -0.985 13.1-162.4-127.1 132.2 -21.4 -4.0 -2.8 126 170 A V E -DE 147 198B 0 21,-2.5 21,-1.7 -2,-0.4 2,-0.3 -0.917 18.0-172.3-107.1 139.1 -20.0 -1.4 -0.4 127 171 A T E +D 146 0B 0 70,-1.1 2,-0.3 -2,-0.4 19,-0.2 -0.915 15.7 124.1-131.2 153.9 -21.4 -1.4 3.2 128 172 A G E -D 145 0B 1 17,-2.0 17,-2.0 -2,-0.3 65,-0.2 -0.945 57.3-110.1 170.4 172.6 -21.0 0.8 6.3 129 173 A W S S+ 0 0 6 63,-0.5 9,-0.4 -2,-0.3 64,-0.1 0.069 72.7 121.7-109.3 19.9 -22.4 3.0 9.1 130 174 A G S S- 0 0 1 1,-0.2 62,-0.3 60,-0.1 61,-0.1 0.033 73.3 -46.8 -73.9-174.6 -21.0 6.3 7.7 131 175 A H - 0 0 29 60,-2.5 6,-0.3 6,-0.1 -1,-0.2 -0.144 38.6-148.5 -56.0 147.5 -23.0 9.4 6.7 132 176 A V S S+ 0 0 47 4,-2.1 -129,-0.5 1,-0.2 5,-0.1 0.458 84.5 5.3 -96.6 -4.0 -26.1 9.0 4.6 133 177 A A B > S-Q 136 0E 31 3,-1.0 3,-2.7 -131,-0.1 -1,-0.2 -0.931 111.7 -52.8-167.0 159.9 -25.6 12.4 2.9 134 178 A P T 3 S- 0 0 89 0, 0.0 -2,-0.1 0, 0.0 3,-0.1 -0.179 123.7 -12.1 -48.4 127.2 -22.8 15.0 3.0 135 179 A S T 3 S+ 0 0 117 1,-0.1 2,-0.6 -4,-0.0 55,-0.0 0.494 110.4 119.1 57.2 10.9 -22.1 16.0 6.7 136 180 A V B < -Q 133 0E 78 -3,-2.7 -4,-2.1 3,-0.0 -3,-1.0 -0.886 57.0-141.6-114.4 107.2 -25.3 14.1 7.7 137 181 A S - 0 0 65 -2,-0.6 2,-0.3 -6,-0.3 -6,-0.1 -0.228 26.5 -99.3 -66.2 147.6 -24.9 11.2 10.1 138 182 A L - 0 0 14 -9,-0.4 -1,-0.1 -8,-0.1 2,-0.1 -0.524 50.5-119.6 -60.9 126.7 -26.8 7.9 9.9 139 183 A L > - 0 0 143 -2,-0.3 3,-2.3 1,-0.1 -1,-0.1 -0.425 43.1 -57.9 -77.9 147.8 -29.6 8.3 12.5 140 184 A T T 3 S+ 0 0 99 1,-0.3 -1,-0.1 2,-0.1 -80,-0.0 -0.260 122.3 37.5 -50.4 141.5 -30.1 6.0 15.5 141 185 A P T 3 S- 0 0 50 0, 0.0 -79,-2.0 0, 0.0 -78,-0.5 -0.952 94.1-147.7 -84.3 12.5 -30.5 3.1 15.7 142 186 A K < - 0 0 50 -3,-2.3 -81,-2.0 -82,-0.2 2,-0.2 0.959 10.5-158.6 64.7 62.2 -28.0 3.1 12.8 143 187 A P B -P 60 0D 21 0, 0.0 -83,-0.2 0, 0.0 -1,-0.1 -0.496 32.8 -96.2 -69.4 138.7 -28.9 0.1 10.6 144 188 A L - 0 0 6 -85,-1.3 -137,-2.8 -2,-0.2 2,-0.3 -0.294 42.3-141.6 -55.9 132.6 -26.0 -1.0 8.3 145 189 A Q E -BD 6 128B 19 -17,-2.0 -17,-2.0 -139,-0.2 2,-0.3 -0.739 15.8-167.6-100.4 149.9 -26.2 0.5 4.9 146 190 A Q E -BD 5 127B 35 -141,-2.8 -141,-2.3 -2,-0.3 2,-0.3 -0.955 4.9-174.0-134.2 151.2 -25.4 -1.2 1.6 147 191 A L E - D 0 126B 10 -21,-1.7 -21,-2.5 -2,-0.3 2,-0.4 -0.950 22.6-132.9-149.6 127.1 -24.9 0.1 -2.0 148 192 A E E + D 0 125B 95 -2,-0.3 -23,-0.2 -23,-0.2 -25,-0.1 -0.672 32.6 178.4 -76.6 128.4 -24.4 -1.8 -5.3 149 193 A V E - D 0 124B 0 -25,-3.0 -25,-2.3 -2,-0.4 2,-0.2 -0.998 24.6-132.4-135.9 127.9 -21.5 -0.2 -7.2 150 194 A P E - D 0 123B 24 0, 0.0 31,-2.0 0, 0.0 -27,-0.2 -0.594 35.7-104.3 -76.7 142.3 -20.0 -1.2 -10.5 151 195 A L E -F 180 0B 6 -29,-1.7 -30,-2.3 -32,-0.3 2,-0.4 -0.423 34.9-164.0 -67.3 137.4 -16.2 -1.5 -10.7 152 196 A I E -F 179 0B 24 27,-2.8 27,-2.3 -32,-0.2 30,-0.0 -0.992 23.0-113.7-126.4 127.0 -14.4 1.4 -12.4 153 197 A S > - 0 0 20 -2,-0.4 4,-2.6 25,-0.2 5,-0.2 -0.161 22.9-118.5 -58.4 153.2 -10.8 1.1 -13.6 154 198 A R H > S+ 0 0 43 23,-0.3 4,-2.7 1,-0.2 19,-0.2 0.831 114.2 56.7 -60.9 -31.8 -8.2 3.3 -11.9 155 199 A E H > S+ 0 0 120 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.926 110.5 40.9 -68.0 -46.5 -7.5 4.9 -15.3 156 200 A T H > S+ 0 0 75 2,-0.2 4,-2.2 1,-0.2 -2,-0.2 0.922 115.5 54.0 -63.7 -41.7 -11.1 6.0 -15.9 157 201 A c H X S+ 0 0 0 -4,-2.6 4,-2.7 1,-0.2 -2,-0.2 0.902 105.3 51.8 -61.4 -45.0 -11.3 7.0 -12.2 158 202 A N H X S+ 0 0 19 -4,-2.7 4,-1.2 1,-0.2 -1,-0.2 0.895 110.0 49.3 -58.8 -41.2 -8.2 9.2 -12.4 159 203 A A H < S+ 0 0 59 -4,-1.6 4,-0.4 2,-0.2 -1,-0.2 0.887 111.3 49.9 -66.9 -37.8 -9.7 11.0 -15.4 160 204 A L H >< S+ 0 0 18 -4,-2.2 3,-1.7 1,-0.2 -2,-0.2 0.928 107.8 52.7 -64.4 -45.2 -13.0 11.5 -13.6 161 205 A Y H 3< S+ 0 0 4 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.780 102.7 60.9 -62.3 -25.4 -11.2 12.9 -10.5 162 206 A N T >< S+ 0 0 112 -4,-1.2 3,-1.1 -5,-0.2 2,-0.5 0.593 79.8 102.2 -77.5 -11.0 -9.4 15.4 -12.7 163 207 A I T < S- 0 0 74 -3,-1.7 -3,-0.0 -4,-0.4 -4,-0.0 -0.663 107.6 -14.1 -77.5 120.6 -12.8 16.9 -13.8 164 208 A D T 3 S+ 0 0 106 -2,-0.5 -1,-0.3 1,-0.2 -2,-0.1 0.859 97.1 174.7 51.7 40.3 -13.3 20.2 -11.8 165 209 A A < - 0 0 53 -3,-1.1 -1,-0.2 1,-0.0 -3,-0.1 -0.369 23.2-139.0 -72.8 155.0 -10.4 19.1 -9.5 166 210 A K > - 0 0 111 3,-0.5 3,-1.7 1,-0.1 -1,-0.0 -0.962 10.5-139.0-119.7 134.0 -9.2 21.5 -6.8 167 211 A P T 3 S+ 0 0 121 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.782 106.1 60.3 -60.9 -26.1 -5.5 21.9 -5.9 168 212 A E T 3 S+ 0 0 143 1,-0.3 -3,-0.0 -3,-0.0 0, 0.0 0.611 109.1 44.1 -75.9 -13.9 -6.5 22.0 -2.2 169 213 A E S < S- 0 0 86 -3,-1.7 -3,-0.5 2,-0.0 -1,-0.3 -0.581 80.8-174.5-130.4 73.0 -8.0 18.5 -2.6 170 214 A P - 0 0 104 0, 0.0 2,-0.3 0, 0.0 -2,-0.0 -0.376 3.4-179.1 -69.4 142.8 -5.5 16.4 -4.6 171 215 A H + 0 0 52 -2,-0.1 2,-0.3 -13,-0.1 -2,-0.0 -0.997 12.1 171.5-142.2 140.6 -6.4 12.8 -5.6 172 216 A F - 0 0 114 -2,-0.3 2,-0.8 -86,-0.1 -14,-0.0 -0.938 28.0-137.6-147.2 127.2 -4.6 10.1 -7.4 173 217 A V - 0 0 2 -2,-0.3 -15,-0.1 -19,-0.2 4,-0.1 -0.763 32.5-143.9 -85.7 111.2 -5.8 6.5 -7.8 174 218 A Q > - 0 0 43 -2,-0.8 3,-1.7 -88,-0.1 -20,-0.0 -0.112 24.5 -99.6 -75.1 171.5 -2.6 4.4 -7.2 175 219 A E T 3 S+ 0 0 151 1,-0.3 -1,-0.1 -21,-0.0 -21,-0.1 0.706 123.4 55.1 -66.4 -19.9 -1.7 1.2 -8.9 176 220 A D T 3 S+ 0 0 4 -22,-0.0 53,-2.9 2,-0.0 2,-0.3 0.086 101.6 82.6 -96.5 21.3 -2.9 -0.8 -5.9 177 221 A M E < - G 0 228B 6 -3,-1.7 2,-0.3 51,-0.3 -23,-0.3 -0.873 50.6-174.7-127.6 157.3 -6.3 0.8 -6.1 178 222 A V E - G 0 227B 17 49,-2.3 49,-3.3 -2,-0.3 2,-0.3 -0.900 17.8-135.3-136.4 164.6 -9.6 0.4 -8.0 179 223 A c E -FG 152 226B 0 -27,-2.3 -27,-2.8 -2,-0.3 2,-0.3 -0.763 14.3-171.8-116.8 169.6 -12.8 2.6 -8.0 180 224 A A E +FG 151 225B 0 45,-1.6 45,-1.1 -29,-0.3 2,-0.3 -0.932 39.9 55.2-159.1 138.4 -16.5 1.8 -7.9 181 225 A G S S- 0 0 2 -31,-2.0 2,-0.3 -2,-0.3 7,-0.1 -1.000 75.1 -45.2 144.6-143.1 -19.6 3.8 -8.3 182 226 A Y - 0 0 56 -2,-0.3 41,-0.4 5,-0.3 40,-0.2 -0.913 23.7-136.2-136.1 150.5 -21.2 6.2 -10.8 183 227 A V S S+ 0 0 68 -2,-0.3 39,-2.6 39,-0.1 2,-0.1 0.871 95.5 63.9 -72.7 -39.9 -20.2 9.1 -13.0 184 228 A E S S- 0 0 146 37,-0.2 3,-0.4 1,-0.1 -2,-0.2 -0.482 95.8-100.3 -82.2 159.4 -23.4 10.9 -11.9 185 229 A G S S+ 0 0 41 1,-0.2 35,-0.2 -2,-0.1 -1,-0.1 -0.085 82.8 59.3 -76.3 168.7 -24.0 11.9 -8.3 186 230 A G S S+ 0 0 36 33,-2.4 2,-0.4 -4,-0.1 -1,-0.2 0.207 81.9 77.4 109.7 -13.6 -26.0 10.5 -5.4 187 231 A K + 0 0 87 -3,-0.4 -5,-0.3 32,-0.1 2,-0.3 -0.810 63.0 86.5-137.9 94.9 -24.7 7.0 -4.8 188 232 A D B S-A 2 0A 4 -186,-1.2 -186,-2.9 -2,-0.4 -184,-0.1 -0.967 71.9 -64.9-164.7-179.7 -21.4 6.3 -2.9 189 233 A A - 0 0 0 -2,-0.3 29,-1.6 -188,-0.2 30,-0.3 -0.456 47.3-164.8 -71.3 152.7 -19.5 5.8 0.4 190 234 A d > - 0 0 0 -59,-0.2 3,-2.3 27,-0.2 4,-0.4 -0.777 40.1 -49.7-129.8 174.8 -19.4 8.7 2.9 191 235 A Q T 3 S+ 0 0 111 25,-0.3 -60,-2.5 1,-0.3 -1,-0.1 -0.176 126.0 32.3 -44.2 132.3 -17.3 9.7 6.0 192 236 A G T 3 S+ 0 0 12 -167,-0.3 -63,-0.5 -62,-0.3 -1,-0.3 0.177 100.6 83.0 100.6 -16.7 -17.3 6.8 8.4 193 237 A D X + 0 0 0 -3,-2.3 3,-1.8 22,-0.3 19,-0.2 0.676 62.1 112.4 -88.4 -21.7 -17.5 4.1 5.7 194 238 A S T 3 S+ 0 0 8 -4,-0.4 -167,-3.0 1,-0.3 19,-0.2 -0.094 71.9 33.3 -60.0 153.7 -13.7 4.0 5.0 195 239 A G T 3 S+ 0 0 0 17,-2.6 -1,-0.3 1,-0.3 -166,-0.2 0.178 97.8 121.0 83.5 -17.6 -11.8 0.9 5.9 196 240 A G < - 0 0 0 -3,-1.8 16,-2.7 1,-0.1 -1,-0.3 -0.147 66.0 -81.8 -76.5 172.1 -15.0 -1.1 5.0 197 241 A P E - H 0 211B 0 0, 0.0 -70,-1.1 0, 0.0 2,-0.6 -0.483 15.5-158.5 -81.2 140.6 -15.5 -3.8 2.5 198 242 A L E -EH 126 210B 0 12,-2.4 12,-1.5 -2,-0.2 11,-1.5 -0.978 29.0-162.0-103.0 106.7 -16.1 -3.8 -1.2 199 243 A S E -EH 125 208B 0 -74,-2.9 -74,-2.6 -2,-0.6 9,-0.2 -0.836 5.5-165.6 -99.2 122.6 -17.6 -7.3 -1.5 200 244 A b E - H 0 207B 0 7,-2.6 7,-2.3 -2,-0.5 2,-0.5 -0.913 16.2-131.7-114.1 136.4 -17.7 -8.8 -5.0 201 245 A P E + H 0 206B 48 0, 0.0 2,-0.4 0, 0.0 5,-0.2 -0.746 33.0 165.1 -86.9 120.8 -19.7 -11.8 -6.2 202 246 A V E > - H 0 205B 46 3,-1.9 3,-2.0 -2,-0.5 -2,-0.0 -0.973 66.1 -22.4-139.4 122.7 -17.7 -14.4 -8.2 203 247 A E T 3 S- 0 0 189 -2,-0.4 3,-0.1 1,-0.3 -1,-0.1 0.867 126.2 -46.5 45.4 52.3 -18.8 -17.9 -9.0 204 248 A G T 3 S+ 0 0 80 1,-0.3 -1,-0.3 0, 0.0 2,-0.2 0.318 123.3 90.6 82.3 -8.0 -21.3 -18.2 -6.1 205 249 A L E < - H 0 202B 92 -3,-2.0 -3,-1.9 -5,-0.0 2,-0.4 -0.568 69.6-124.8-112.2 175.0 -18.9 -16.8 -3.5 206 250 A W E - H 0 201B 97 -5,-0.2 -96,-0.8 -2,-0.2 2,-0.3 -0.986 24.2-168.5-122.8 135.7 -18.1 -13.3 -2.2 207 251 A Y E -cH 110 200B 57 -7,-2.3 -7,-2.6 -2,-0.4 2,-1.6 -0.925 31.4-117.5-124.1 147.9 -14.6 -11.9 -2.1 208 252 A L E + H 0 199B 0 -98,-2.4 22,-0.2 -2,-0.3 -9,-0.2 -0.661 43.9 164.3 -78.9 86.9 -13.0 -8.8 -0.4 209 253 A T E + 0 0 1 -2,-1.6 21,-1.9 -11,-1.5 22,-0.5 0.902 60.2 11.1 -71.5 -41.1 -12.1 -7.1 -3.7 210 254 A G E -IH 229 198B 0 -12,-1.5 -12,-2.4 19,-0.2 2,-0.4 -0.918 53.4-144.3-141.9 160.7 -11.5 -3.7 -2.0 211 255 A I E -IH 228 197B 0 17,-1.6 17,-2.7 -2,-0.3 2,-0.2 -0.999 45.3-104.5-123.0 124.8 -11.1 -1.8 1.2 212 256 A V E +I 227 0B 0 -16,-2.7 -17,-2.6 -2,-0.4 15,-0.3 -0.313 48.9 164.6 -56.2 116.4 -12.5 1.8 1.2 213 257 A S E S+ 0 0 12 13,-2.8 2,-0.5 1,-0.3 14,-0.2 0.832 73.8 19.8-101.4 -50.8 -9.5 4.1 0.9 214 258 A W E S+I 226 0B 46 12,-2.2 12,-2.3 1,-0.1 -1,-0.3 -0.939 71.6 146.5-119.6 107.0 -11.1 7.4 -0.1 215 259 A G + 0 0 1 -2,-0.5 -22,-0.3 -3,-0.2 3,-0.3 0.036 42.6 94.8-127.2 26.0 -14.8 7.3 0.8 216 260 A D + 0 0 66 -26,-0.2 -25,-0.3 1,-0.2 -1,-0.1 0.492 56.6 91.0 -96.9 -3.8 -15.5 10.9 1.7 217 261 A A > - 0 0 19 -27,-0.1 3,-1.1 -3,-0.1 -1,-0.2 0.818 68.8-165.8 -60.9 -34.8 -16.8 12.0 -1.7 218 262 A d T 3 - 0 0 10 -29,-1.6 -28,-0.2 -3,-0.3 -1,-0.1 0.843 65.9 -39.0 50.8 49.2 -20.3 11.0 -0.6 219 263 A G T 3 S+ 0 0 13 -30,-0.3 -33,-2.4 4,-0.3 -1,-0.3 0.545 88.7 152.2 85.7 8.0 -22.1 11.0 -3.9 220 264 A A X - 0 0 49 -3,-1.1 3,-1.0 -35,-0.2 -1,-0.3 -0.419 55.4 -98.0 -61.7 145.7 -20.5 14.0 -5.6 221 265 A R T 3 S+ 0 0 146 1,-0.2 -37,-0.2 -36,-0.1 -38,-0.1 -0.339 105.3 16.6 -65.5 150.2 -20.4 13.7 -9.4 222 266 A N T 3 S+ 0 0 19 -39,-2.6 -1,-0.2 -40,-0.2 -59,-0.2 0.721 102.6 101.0 59.6 26.2 -17.2 12.4 -11.0 223 267 A R < + 0 0 37 -3,-1.0 -4,-0.3 -41,-0.4 -3,-0.2 -0.439 48.0 176.2-137.8 61.6 -16.0 11.1 -7.6 224 268 A P - 0 0 0 0, 0.0 -43,-0.2 0, 0.0 -36,-0.1 -0.360 46.0 -84.0 -66.1 151.4 -16.5 7.3 -7.4 225 269 A G E -G 180 0B 1 -45,-1.1 -45,-1.6 -10,-0.1 2,-0.5 -0.194 40.5-136.2 -55.3 142.9 -15.2 5.7 -4.2 226 270 A V E -GI 179 214B 8 -12,-2.3 -13,-2.8 -47,-0.2 -12,-2.2 -0.907 24.1-171.3-107.6 130.6 -11.5 4.7 -4.2 227 271 A Y E -GI 178 212B 0 -49,-3.3 -49,-2.3 -2,-0.5 2,-0.4 -0.941 25.5-124.6-126.9 141.9 -10.5 1.3 -2.8 228 272 A T E -GI 177 211B 0 -17,-2.7 -17,-1.6 -2,-0.4 2,-0.5 -0.721 36.5-120.9 -77.7 130.1 -7.3 -0.5 -2.0 229 273 A L E > - I 0 210B 33 -53,-2.9 3,-0.9 -2,-0.4 4,-0.3 -0.644 13.0-154.7 -74.1 119.9 -7.2 -3.9 -3.9 230 274 A A G > S+ 0 0 0 -21,-1.9 3,-1.8 -2,-0.5 4,-0.2 0.827 93.0 67.0 -63.1 -30.4 -6.9 -6.7 -1.4 231 275 A S G > S+ 0 0 15 -22,-0.5 3,-1.1 1,-0.3 4,-0.3 0.835 90.2 63.1 -58.4 -33.2 -5.2 -8.8 -4.2 232 276 A S G < S+ 0 0 58 -3,-0.9 -1,-0.3 1,-0.2 -2,-0.2 0.638 111.9 37.4 -66.2 -12.3 -2.2 -6.4 -4.1 233 277 A Y G <> S+ 0 0 19 -3,-1.8 4,-2.9 -4,-0.3 5,-0.2 0.223 78.2 111.3-126.7 13.7 -1.6 -7.6 -0.5 234 278 A A H <> S+ 0 0 22 -3,-1.1 4,-2.5 -4,-0.2 5,-0.2 0.892 82.7 48.4 -54.9 -44.0 -2.5 -11.3 -0.6 235 279 A S H > S+ 0 0 95 -4,-0.3 4,-2.1 2,-0.2 -1,-0.2 0.922 113.6 45.7 -64.6 -46.9 1.2 -12.3 -0.1 236 280 A W H > S+ 0 0 41 2,-0.2 4,-2.4 1,-0.2 -2,-0.2 0.906 113.6 49.4 -62.7 -46.1 1.7 -9.9 2.9 237 281 A I H X S+ 0 0 6 -4,-2.9 4,-2.9 1,-0.2 5,-0.3 0.943 111.7 47.9 -60.5 -49.1 -1.6 -11.0 4.5 238 282 A Q H X S+ 0 0 139 -4,-2.5 4,-2.2 -5,-0.2 5,-0.2 0.891 111.7 51.4 -61.4 -38.8 -0.9 -14.7 4.2 239 283 A S H X S+ 0 0 71 -4,-2.1 4,-2.3 -5,-0.2 -1,-0.2 0.945 114.4 42.1 -62.3 -48.3 2.6 -14.2 5.6 240 284 A K H X S+ 0 0 47 -4,-2.4 4,-2.0 2,-0.2 -2,-0.2 0.920 115.9 47.7 -65.5 -46.9 1.4 -12.3 8.6 241 285 A V H < S+ 0 0 39 -4,-2.9 4,-0.4 -5,-0.2 -1,-0.2 0.887 114.8 46.7 -62.9 -40.6 -1.6 -14.6 9.3 242 286 A T H >< S+ 0 0 69 -4,-2.2 3,-0.7 -5,-0.3 -2,-0.2 0.918 113.4 46.1 -70.4 -45.1 0.6 -17.7 9.0 243 287 A E H 3< S+ 0 0 147 -4,-2.3 -1,-0.2 -5,-0.2 -2,-0.2 0.874 120.6 39.3 -65.0 -36.2 3.5 -16.5 11.2 244 288 A L T 3< S+ 0 0 58 -4,-2.0 -1,-0.2 -5,-0.2 -2,-0.2 0.278 81.3 141.2-101.1 10.1 1.2 -15.2 13.9 245 289 A Q < - 0 0 134 -3,-0.7 2,-0.1 -4,-0.4 -3,-0.1 -0.226 46.6-128.3 -56.8 137.2 -1.5 -18.0 13.9 246 290 A L - 0 0 58 1,-0.1 -1,-0.1 0, 0.0 -212,-0.0 -0.386 27.7 -88.7 -84.0 162.8 -2.7 -19.0 17.4 247 291 A V 0 0 130 1,-0.1 -1,-0.1 -2,-0.1 0, 0.0 -0.455 360.0 360.0 -64.5 142.9 -2.9 -22.4 18.9 248 292 A P 0 0 173 0, 0.0 -1,-0.1 0, 0.0 0, 0.0 0.068 360.0 360.0 -72.4 360.0 -6.2 -24.2 18.1