==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER ISOMERASE 12-JUN-08 3DG3 . COMPND 2 MOLECULE: MUCONATE CYCLOISOMERASE; . SOURCE 2 ORGANISM_SCIENTIFIC: MYCOBACTERIUM SMEGMATIS; . AUTHOR A.A.FEDOROV,E.V.FEDOROV,A.SAKAI,J.A.GERLT,S.C.ALMO . 355 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14247.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 243 68.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 31 8.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 33 9.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 13 3.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 29 8.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 117 33.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 2.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 2 0 1 1 0 4 1 0 1 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 4 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 5 0 1 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A M 0 0 65 0, 0.0 68,-2.1 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 48.5 42.5 29.3 -5.5 2 2 A K B -A 68 0A 87 66,-0.2 27,-1.8 67,-0.1 2,-0.4 -0.826 360.0-117.3-102.6 138.8 43.6 26.4 -7.7 3 3 A I E +B 28 0B 1 64,-3.1 63,-2.5 -2,-0.4 25,-0.3 -0.613 35.4 170.4 -74.8 123.7 44.4 23.0 -6.3 4 4 A V E + 0 0 71 23,-2.9 2,-0.3 -2,-0.4 24,-0.2 0.611 64.6 1.6-107.0 -19.3 48.1 22.2 -7.0 5 5 A A E -B 27 0B 37 22,-1.4 22,-3.2 59,-0.1 2,-0.4 -0.973 50.1-157.8-166.9 152.0 48.4 19.1 -4.9 6 6 A I E -B 26 0B 15 -2,-0.3 2,-0.3 20,-0.2 20,-0.2 -0.983 20.2-170.7-136.9 121.5 46.5 16.7 -2.5 7 7 A G E -B 25 0B 20 18,-2.6 18,-2.2 -2,-0.4 2,-0.4 -0.795 15.3-156.8-116.4 158.9 48.4 14.6 0.0 8 8 A A E -B 24 0B 6 -2,-0.3 16,-0.2 16,-0.2 49,-0.1 -0.931 13.0-175.2-135.7 108.7 47.4 11.7 2.4 9 9 A I E -B 23 0B 7 14,-3.0 14,-3.3 -2,-0.4 2,-0.2 -0.907 16.3-142.8-111.2 115.9 49.6 11.2 5.4 10 10 A P E +B 22 0B 18 0, 0.0 345,-2.6 0, 0.0 346,-0.4 -0.505 27.2 172.1 -75.1 141.2 49.0 8.2 7.7 11 11 A F E -BC 21 354B 0 10,-2.4 10,-0.8 343,-0.3 2,-0.4 -0.971 19.8-149.7-145.7 158.9 49.5 8.8 11.5 12 12 A S E +B 20 0B 33 341,-2.4 8,-0.2 -2,-0.3 10,-0.0 -0.991 10.9 179.3-138.1 129.8 48.9 6.9 14.7 13 13 A I E -B 19 0B 0 6,-1.8 6,-3.3 -2,-0.4 306,-0.0 -0.990 29.3-123.6-130.1 121.6 48.1 8.2 18.2 14 14 A P - 0 0 67 0, 0.0 304,-2.4 0, 0.0 305,-0.3 -0.227 22.7-122.7 -62.6 150.7 47.6 5.9 21.1 15 15 A Y B E 317 0C 68 302,-0.2 302,-0.2 1,-0.2 301,-0.1 -0.642 360.0 360.0 -92.0 153.2 44.4 6.0 23.2 16 16 A T 0 0 148 300,-3.1 -1,-0.2 -2,-0.2 302,-0.1 0.691 360.0 360.0 -79.1 360.0 44.4 6.6 26.9 17 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 18 28 A A 0 0 80 0, 0.0 2,-0.9 0, 0.0 299,-0.0 0.000 360.0 360.0 360.0 146.5 44.9 3.8 19.0 19 29 A A E -B 13 0B 2 -6,-3.3 -6,-1.8 1,-0.1 2,-1.0 -0.771 360.0-178.7 -89.9 104.7 43.7 6.3 16.4 20 30 A E E +B 12 0B 107 -2,-0.9 -8,-0.2 -8,-0.2 2,-0.1 -0.747 26.3 152.5-104.3 83.0 45.2 5.3 13.0 21 31 A H E -B 11 0B 0 -2,-1.0 -10,-2.4 -10,-0.8 2,-0.4 -0.380 42.7-118.4-105.1-177.2 43.9 8.1 10.8 22 32 A V E -BD 10 38B 0 16,-1.2 16,-2.0 -12,-0.2 2,-0.6 -0.990 15.7-142.9-127.7 124.3 45.0 9.8 7.6 23 33 A L E -BD 9 37B 0 -14,-3.3 -14,-3.0 -2,-0.4 2,-0.5 -0.773 19.4-159.5 -86.9 122.1 45.8 13.5 7.4 24 34 A V E -BD 8 36B 0 12,-3.3 12,-1.4 -2,-0.6 2,-0.4 -0.891 7.7-170.6-106.5 130.3 44.5 14.9 4.1 25 35 A R E -BD 7 35B 69 -18,-2.2 -18,-2.6 -2,-0.5 2,-0.6 -0.976 11.5-161.9-127.6 127.0 46.0 18.1 2.8 26 36 A V E -BD 6 34B 0 8,-2.6 8,-2.7 -2,-0.4 2,-0.4 -0.923 14.7-159.6-106.7 114.4 44.8 20.2 -0.2 27 37 A H E -BD 5 33B 51 -22,-3.2 -23,-2.9 -2,-0.6 -22,-1.4 -0.774 5.8-160.8 -96.9 137.0 47.4 22.6 -1.4 28 38 A T E > -B 3 0B 7 4,-2.4 3,-1.6 -2,-0.4 -25,-0.2 -0.685 33.6-111.2-112.6 167.8 46.5 25.7 -3.5 29 39 A D T 3 S+ 0 0 85 -27,-1.8 -26,-0.1 1,-0.3 -1,-0.0 0.426 115.4 65.9 -75.6 2.7 48.5 28.0 -5.9 30 40 A D T 3 S- 0 0 93 -28,-0.2 -1,-0.3 2,-0.2 3,-0.1 0.297 119.6-107.3-103.0 4.4 48.0 30.7 -3.2 31 41 A G S < S+ 0 0 68 -3,-1.6 2,-0.3 1,-0.3 -2,-0.1 0.506 76.8 137.4 82.1 3.7 50.2 28.8 -0.7 32 42 A I - 0 0 31 67,-0.0 -4,-2.4 68,-0.0 2,-0.5 -0.622 38.3-159.7 -85.8 141.9 47.1 27.9 1.3 33 43 A V E -D 27 0B 49 -2,-0.3 2,-0.3 -6,-0.2 -6,-0.2 -0.965 1.5-162.2-125.9 115.3 46.8 24.4 2.7 34 44 A G E -D 26 0B 0 -8,-2.7 -8,-2.6 -2,-0.5 2,-0.3 -0.700 15.7-164.2 -92.3 148.1 43.4 23.0 3.8 35 45 A V E +D 25 0B 10 -2,-0.3 2,-0.3 -10,-0.2 -10,-0.2 -0.908 21.6 150.5-135.2 163.1 43.3 20.0 6.0 36 46 A A E -D 24 0B 0 -12,-1.4 -12,-3.3 -2,-0.3 2,-0.3 -0.937 33.1-117.1-171.8 168.7 41.0 17.2 7.4 37 47 A E E -D 23 0B 3 -2,-0.3 -14,-0.2 -14,-0.2 57,-0.1 -0.881 8.5-149.7-122.3 156.1 41.3 13.7 8.6 38 48 A A E -D 22 0B 0 -16,-2.0 -16,-1.2 -2,-0.3 50,-0.1 -0.969 12.6-152.8-125.0 111.4 40.0 10.4 7.3 39 49 A P - 0 0 0 0, 0.0 2,-0.5 0, 0.0 -18,-0.2 -0.760 15.2-136.4 -87.8 113.7 39.3 7.7 10.0 40 50 A P + 0 0 11 0, 0.0 -20,-0.2 0, 0.0 9,-0.1 -0.561 27.0 175.5 -72.1 121.3 39.6 4.2 8.5 41 51 A R >>> + 0 0 40 -2,-0.5 4,-3.1 1,-0.1 3,-2.1 -0.751 8.3 175.9-126.7 81.9 36.7 2.1 9.8 42 52 A P T 345S+ 0 0 62 0, 0.0 -1,-0.1 0, 0.0 6,-0.1 0.803 82.5 54.4 -57.4 -27.2 36.9 -1.3 8.1 43 53 A F T 345S+ 0 0 178 2,-0.1 -2,-0.0 1,-0.1 0, 0.0 0.356 120.2 30.1 -89.9 6.3 33.9 -2.5 10.2 44 54 A T T <45S+ 0 0 52 -3,-2.1 -1,-0.1 3,-0.1 0, 0.0 0.614 143.1 4.1-127.1 -44.5 31.7 0.4 9.2 45 55 A Y T <5S- 0 0 39 -4,-3.1 40,-0.3 2,-0.2 -2,-0.1 0.526 91.2-118.0-121.3 -16.2 32.7 1.4 5.6 46 56 A G < + 0 0 53 -5,-1.6 2,-0.2 1,-0.3 -3,-0.1 0.533 66.0 138.0 88.5 5.9 35.4 -1.2 4.7 47 57 A E - 0 0 10 -6,-0.5 -1,-0.3 -8,-0.1 2,-0.3 -0.562 35.4-160.0 -85.5 150.1 38.2 1.4 4.4 48 58 A T > - 0 0 69 -2,-0.2 4,-2.5 -7,-0.1 5,-0.2 -0.852 31.6-112.6-123.0 161.5 41.7 0.7 5.7 49 59 A Q H > S+ 0 0 38 -2,-0.3 4,-1.8 1,-0.2 5,-0.2 0.936 121.8 46.2 -59.7 -44.2 44.4 3.2 6.5 50 60 A T H > S+ 0 0 114 1,-0.2 4,-2.0 2,-0.2 -1,-0.2 0.902 112.3 51.7 -63.8 -41.1 46.5 1.8 3.6 51 61 A G H > S+ 0 0 27 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.854 106.4 52.6 -65.0 -37.7 43.4 1.9 1.3 52 62 A I H X S+ 0 0 0 -4,-2.5 4,-2.1 2,-0.2 5,-0.2 0.937 110.7 46.6 -64.3 -48.2 42.6 5.5 2.0 53 63 A V H X S+ 0 0 22 -4,-1.8 4,-2.6 -5,-0.2 5,-0.3 0.915 113.8 51.0 -60.6 -41.0 46.1 6.7 1.2 54 64 A A H X S+ 0 0 28 -4,-2.0 4,-2.8 1,-0.2 5,-0.4 0.930 109.9 46.0 -64.0 -48.1 46.0 4.6 -2.0 55 65 A V H X>S+ 0 0 12 -4,-2.6 5,-2.2 2,-0.2 4,-1.9 0.867 116.0 47.2 -66.4 -33.3 42.7 5.8 -3.4 56 66 A I H <>S+ 0 0 0 -4,-2.1 5,-3.1 3,-0.2 -2,-0.2 0.950 118.0 39.4 -72.0 -48.2 43.6 9.4 -2.7 57 67 A E H <5S+ 0 0 116 -4,-2.6 -2,-0.2 -5,-0.2 -3,-0.2 0.884 126.2 36.2 -68.7 -38.6 47.1 9.2 -4.2 58 68 A Q H <5S+ 0 0 125 -4,-2.8 -3,-0.2 -5,-0.3 -2,-0.2 0.765 135.1 7.2 -88.1 -28.0 46.1 7.0 -7.1 59 69 A Y T X5S+ 0 0 142 -4,-1.9 4,-1.1 -5,-0.4 -3,-0.2 0.759 124.5 40.2-121.0 -58.2 42.6 8.2 -8.0 60 70 A F H >> -A 2 0A 33 -66,-0.3 3,-1.1 -2,-0.1 -66,-0.2 -0.513 25.9-107.7 -91.3 166.8 39.6 25.8 -8.2 69 79 A L T 3 S+ 0 0 1 -68,-2.1 3,-0.2 1,-0.3 -67,-0.1 0.532 117.9 61.7 -71.9 -4.5 38.1 25.9 -4.7 70 80 A T T 3 S+ 0 0 94 -69,-0.3 -1,-0.3 1,-0.2 3,-0.1 -0.114 84.1 75.8-113.0 34.4 34.9 27.2 -6.2 71 81 A E X> + 0 0 73 -3,-1.1 4,-2.1 1,-0.1 3,-0.9 -0.280 52.2 142.3-132.4 41.4 34.2 24.2 -8.4 72 82 A R H 3> + 0 0 76 1,-0.3 4,-2.8 -3,-0.2 5,-0.1 0.830 69.2 54.6 -54.9 -37.1 33.0 22.0 -5.6 73 83 A E H 3> S+ 0 0 79 2,-0.2 4,-2.2 1,-0.2 -1,-0.3 0.806 106.6 51.1 -71.1 -26.7 30.3 20.4 -7.7 74 84 A V H <> S+ 0 0 51 -3,-0.9 4,-2.6 2,-0.2 -2,-0.2 0.923 113.4 45.1 -72.3 -43.3 32.9 19.3 -10.3 75 85 A A H X S+ 0 0 5 -4,-2.1 4,-2.6 2,-0.2 5,-0.3 0.912 113.0 51.5 -63.8 -41.7 35.0 17.8 -7.6 76 86 A H H X S+ 0 0 58 -4,-2.8 4,-1.8 -5,-0.2 -2,-0.2 0.925 112.5 45.1 -60.7 -46.6 31.9 16.2 -6.1 77 87 A T H < S+ 0 0 88 -4,-2.2 4,-0.4 2,-0.2 -2,-0.2 0.887 113.5 49.3 -66.7 -41.6 30.9 14.7 -9.4 78 88 A R H >< S+ 0 0 111 -4,-2.6 3,-1.3 1,-0.2 4,-0.4 0.932 113.0 45.8 -65.8 -45.6 34.4 13.4 -10.3 79 89 A M H >< S+ 0 0 14 -4,-2.6 3,-1.7 1,-0.3 -1,-0.2 0.857 102.9 66.8 -65.2 -32.5 34.9 11.8 -6.9 80 90 A A T 3< S+ 0 0 58 -4,-1.8 -1,-0.3 1,-0.3 -2,-0.2 0.649 83.4 74.1 -63.2 -15.9 31.4 10.2 -7.2 81 91 A R T < S+ 0 0 217 -3,-1.3 2,-0.5 -4,-0.4 -1,-0.3 0.844 88.2 69.8 -65.9 -32.3 32.6 8.1 -10.1 82 92 A T S < S- 0 0 37 -3,-1.7 2,-0.2 -4,-0.4 -23,-0.0 -0.751 88.8-132.0 -87.9 130.0 34.5 6.0 -7.5 83 93 A V - 0 0 129 -2,-0.5 -2,-0.1 2,-0.0 -3,-0.0 -0.533 63.7 -15.1 -81.9 147.8 32.1 4.0 -5.3 84 94 A G S S+ 0 0 40 -2,-0.2 5,-0.2 1,-0.1 -2,-0.1 -0.306 70.3 124.6 65.0-142.1 32.4 3.9 -1.6 85 95 A N > + 0 0 44 -40,-0.3 4,-2.0 3,-0.1 5,-0.2 0.901 38.9 171.5 49.2 47.7 35.6 5.2 0.0 86 96 A P H > + 0 0 18 0, 0.0 4,-2.7 0, 0.0 5,-0.2 0.890 66.9 43.9 -55.6 -50.7 33.5 7.6 2.1 87 97 A T H > S+ 0 0 0 2,-0.2 4,-2.4 1,-0.2 5,-0.2 0.834 111.4 55.5 -69.7 -28.9 36.0 9.1 4.5 88 98 A A H > S+ 0 0 0 2,-0.2 4,-1.7 1,-0.2 -1,-0.2 0.947 113.9 40.3 -65.1 -47.5 38.6 9.5 1.8 89 99 A K H X S+ 0 0 47 -4,-2.0 4,-2.3 1,-0.2 -2,-0.2 0.915 115.3 51.7 -65.5 -45.5 36.2 11.6 -0.2 90 100 A A H X S+ 0 0 4 -4,-2.7 4,-2.7 168,-0.3 172,-0.2 0.893 107.3 52.7 -60.0 -42.4 34.8 13.4 2.8 91 101 A A H X S+ 0 0 0 -4,-2.4 4,-2.5 167,-0.2 -1,-0.2 0.916 109.6 48.5 -61.7 -43.6 38.3 14.4 4.0 92 102 A I H X S+ 0 0 0 -4,-1.7 4,-2.2 2,-0.2 -1,-0.2 0.929 112.2 49.4 -63.0 -43.8 39.1 15.9 0.6 93 103 A D H X S+ 0 0 20 -4,-2.3 4,-2.1 1,-0.2 -2,-0.2 0.932 113.8 45.0 -60.8 -46.1 35.9 17.9 0.5 94 104 A M H X S+ 0 0 2 -4,-2.7 4,-2.2 1,-0.2 -59,-0.2 0.868 111.7 51.9 -68.3 -35.4 36.4 19.2 4.0 95 105 A A H X S+ 0 0 0 -4,-2.5 4,-2.5 -5,-0.2 -1,-0.2 0.876 109.4 51.3 -67.1 -36.5 40.0 20.1 3.3 96 106 A M H X S+ 0 0 4 -4,-2.2 4,-2.4 -5,-0.2 -2,-0.2 0.918 110.6 47.8 -65.0 -43.3 38.9 22.0 0.2 97 107 A W H X S+ 0 0 16 -4,-2.1 4,-2.6 2,-0.2 -2,-0.2 0.867 110.2 52.8 -64.1 -37.1 36.3 23.9 2.3 98 108 A D H X S+ 0 0 2 -4,-2.2 4,-2.4 2,-0.2 -2,-0.2 0.951 111.0 46.5 -62.8 -48.1 39.0 24.6 4.9 99 109 A A H X S+ 0 0 0 -4,-2.5 4,-2.2 1,-0.2 -2,-0.2 0.885 111.8 51.5 -61.1 -40.5 41.3 26.1 2.1 100 110 A L H X S+ 0 0 11 -4,-2.4 4,-1.8 2,-0.2 -1,-0.2 0.929 109.5 49.8 -63.2 -45.2 38.4 28.1 0.7 101 111 A G H X>S+ 0 0 0 -4,-2.6 5,-2.4 1,-0.2 4,-1.2 0.905 111.0 48.7 -60.9 -42.7 37.6 29.5 4.1 102 112 A Q H <5S+ 0 0 68 -4,-2.4 -1,-0.2 237,-0.2 3,-0.2 0.894 110.6 52.1 -64.2 -38.6 41.2 30.5 4.7 103 113 A S H <5S+ 0 0 35 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.805 119.4 34.4 -67.2 -30.8 41.3 32.1 1.2 104 114 A L H <5S- 0 0 81 -4,-1.8 -1,-0.2 2,-0.2 -2,-0.2 0.443 106.8-120.8-103.4 -3.4 38.1 34.2 1.9 105 115 A R T <5S+ 0 0 202 -4,-1.2 2,-0.3 1,-0.3 -3,-0.2 0.902 73.1 124.4 62.8 41.6 38.8 34.8 5.6 106 116 A L < - 0 0 62 -5,-2.4 234,-3.3 -6,-0.2 -1,-0.3 -0.974 63.1-116.4-131.7 145.8 35.5 33.1 6.5 107 117 A S B > -f 340 0D 3 -2,-0.3 4,-2.2 232,-0.3 234,-0.2 -0.469 23.9-122.2 -78.0 153.8 34.8 30.2 8.8 108 118 A V H > S+ 0 0 0 232,-2.2 4,-2.3 1,-0.2 5,-0.2 0.926 112.2 58.5 -60.2 -43.0 33.4 27.0 7.3 109 119 A S H >>S+ 0 0 1 231,-0.4 5,-2.4 1,-0.2 4,-0.9 0.914 108.7 42.4 -53.4 -49.3 30.4 27.3 9.7 110 120 A E H >45S+ 0 0 83 3,-0.2 3,-0.6 1,-0.2 -1,-0.2 0.897 111.3 54.6 -69.5 -37.0 29.4 30.8 8.4 111 121 A M H 3<5S+ 0 0 45 -4,-2.2 -1,-0.2 1,-0.2 -2,-0.2 0.875 109.0 50.7 -62.3 -34.3 30.0 29.8 4.7 112 122 A L H 3<5S- 0 0 21 -4,-2.3 -1,-0.2 -5,-0.2 -2,-0.2 0.692 141.7 -65.6 -76.8 -20.1 27.6 26.9 5.2 113 123 A G T <<5 - 0 0 51 -4,-0.9 -3,-0.2 -3,-0.6 -2,-0.1 0.161 49.5-136.0 159.2 -28.7 24.8 29.0 6.8 114 124 A G < + 0 0 37 -5,-2.4 186,-0.2 -6,-0.2 -4,-0.1 0.800 42.2 157.0 52.4 39.6 26.0 30.4 10.2 115 125 A Y - 0 0 146 185,-1.0 2,-0.3 -6,-0.2 185,-0.2 0.926 67.5 -11.1 -59.7 -46.2 22.8 29.6 12.1 116 126 A T - 0 0 46 183,-2.6 -1,-0.1 -7,-0.1 -2,-0.1 -0.863 57.3-124.2-145.1 179.2 24.6 29.5 15.4 117 127 A D S S+ 0 0 61 -2,-0.3 218,-2.2 1,-0.1 2,-0.3 0.369 83.0 28.7-112.9 5.7 28.1 29.5 17.0 118 128 A R E -G 334 0E 91 216,-0.3 2,-0.3 181,-0.1 216,-0.2 -0.992 57.4-142.9-159.8 163.2 28.0 26.5 19.2 119 129 A M E -G 333 0E 2 214,-2.3 214,-2.4 -2,-0.3 2,-0.2 -0.954 26.4-115.3-130.2 149.7 26.6 23.0 19.8 120 130 A R E -G 332 0E 83 -2,-0.3 189,-3.0 185,-0.3 2,-0.4 -0.584 38.8-131.0 -78.0 149.0 25.6 21.1 22.9 121 131 A V E -i 309 0F 1 210,-3.0 27,-0.7 187,-0.2 26,-0.5 -0.843 17.7-162.8-109.9 139.7 27.8 18.1 23.5 122 132 A S E -ij 310 148F 2 187,-2.3 189,-0.8 -2,-0.4 190,-0.6 -0.811 7.9-149.5-113.9 159.1 26.8 14.5 24.2 123 133 A H E - j 0 149F 8 25,-2.2 27,-2.6 -2,-0.3 2,-0.4 -0.986 7.3-143.5-129.7 139.0 29.1 11.7 25.6 124 134 A M E + j 0 150F 45 -2,-0.4 2,-0.3 25,-0.2 27,-0.2 -0.842 28.7 152.2-107.2 141.7 28.8 8.0 24.9 125 135 A L E + j 0 151F 8 25,-1.9 27,-2.8 -2,-0.4 2,-0.3 -0.964 9.5 107.2-155.1 167.3 29.5 5.3 27.4 126 136 A G E + j 0 152F 20 -2,-0.3 27,-0.1 25,-0.2 3,-0.1 -0.909 28.7 99.0 149.0-176.7 28.6 1.7 28.2 127 137 A F S S+ 0 0 106 25,-0.5 2,-0.3 1,-0.3 26,-0.1 0.836 81.3 81.5 68.0 35.8 29.6 -2.0 28.3 128 138 A D S S- 0 0 57 32,-0.1 -1,-0.3 33,-0.0 36,-0.1 -0.898 91.3 -56.3-153.2 178.4 30.5 -1.9 32.0 129 139 A D > - 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