==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=1-APR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 02-FEB-12 4DJW . COMPND 2 MOLECULE: BETA-SECRETASE 1; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.STRICKLAND,J.CUMMING . 779 2 6 6 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 33160.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 516 66.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 36 4.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 223 28.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 6 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 6 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 79 10.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 82 10.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 64 8.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 6 0 2 0 2 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 8 4 6 6 8 0 1 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 2 0 4 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 58 A G 0 0 60 0, 0.0 3,-0.3 0, 0.0 183,-0.1 0.000 360.0 360.0 360.0 108.2 36.7 -15.3 29.5 2 59 A S + 0 0 103 181,-0.3 3,-0.1 1,-0.2 182,-0.1 0.385 360.0 61.3 -99.4 5.6 33.8 -17.3 28.2 3 60 A F >> + 0 0 59 1,-0.1 3,-1.5 2,-0.1 4,-1.3 -0.390 54.3 151.4-127.5 55.7 32.6 -15.0 25.4 4 61 A V T 34 + 0 0 116 -3,-0.3 3,-0.2 1,-0.3 -1,-0.1 0.833 69.0 62.6 -54.5 -38.3 35.7 -14.9 23.1 5 62 A E T 34 S+ 0 0 98 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.1 0.769 112.4 37.1 -60.1 -27.3 33.6 -14.2 20.0 6 63 A M T X4 S+ 0 0 12 -3,-1.5 3,-1.2 171,-0.0 172,-0.7 0.627 88.5 108.8-102.3 -15.5 32.4 -10.9 21.5 7 64 A V T 3< S+ 0 0 35 -4,-1.3 170,-0.1 1,-0.2 87,-0.0 -0.412 90.7 9.4 -63.1 136.0 35.6 -9.7 23.2 8 65 A D T 3 S+ 0 0 88 149,-0.1 -1,-0.2 1,-0.1 169,-0.2 0.774 84.7 133.0 65.7 33.2 37.2 -6.7 21.4 9 66 A N < + 0 0 19 -3,-1.2 12,-0.6 84,-0.1 2,-0.3 0.408 50.0 82.8 -94.3 3.8 34.2 -6.2 19.1 10 67 A L E -AB 20 176A 0 166,-2.4 165,-2.3 10,-0.1 166,-0.9 -0.780 51.0-178.9-106.6 155.5 34.0 -2.3 19.7 11 68 A R E +A 19 0A 74 8,-1.7 8,-2.9 -2,-0.3 2,-0.3 -0.922 37.4 63.5-139.8 163.1 36.0 0.5 18.2 12 69 A G E -A 18 0A 8 158,-0.5 2,-0.3 -2,-0.3 6,-0.2 -0.837 62.9-100.8 124.7-160.0 35.9 4.3 18.7 13 70 A K E >> -A 17 0A 63 4,-1.3 4,-2.3 -2,-0.3 3,-0.9 -0.956 36.0 -91.5-161.5 164.2 36.6 6.7 21.6 14 71 A S T 34 S+ 0 0 11 -2,-0.3 325,-0.2 1,-0.2 4,-0.1 0.853 119.1 49.3 -52.7 -44.5 34.8 8.8 24.2 15 72 A G T 34 S+ 0 0 28 1,-0.2 -1,-0.2 2,-0.1 221,-0.1 0.695 124.3 27.3 -70.9 -25.5 34.4 12.0 22.1 16 73 A Q T <4 S- 0 0 51 -3,-0.9 -2,-0.2 1,-0.2 -1,-0.2 0.504 114.8-108.7-115.6 -8.2 33.0 10.3 18.9 17 74 A G E < -A 13 0A 8 -4,-2.3 -4,-1.3 17,-0.1 2,-0.4 -0.028 24.7 -88.5 98.1 159.9 31.3 7.2 20.5 18 75 A Y E -A 12 0A 1 17,-0.4 17,-3.0 215,-0.3 2,-0.3 -0.885 46.1-167.6-105.5 133.1 32.0 3.4 20.6 19 76 A Y E -AC 11 34A 5 -8,-2.9 -8,-1.7 -2,-0.4 2,-0.3 -0.901 15.4-155.1-128.3 156.2 30.5 1.3 17.9 20 77 A V E -AC 10 33A 2 13,-2.5 13,-3.0 -2,-0.3 2,-0.3 -0.903 30.0-109.1-122.5 149.3 29.8 -2.3 17.0 21 78 A E E + C 0 32A 60 -12,-0.6 72,-0.4 -2,-0.3 2,-0.3 -0.629 42.4 171.3 -79.3 138.9 29.5 -3.9 13.5 22 79 A M E - C 0 31A 0 9,-3.0 9,-2.7 -2,-0.3 2,-0.4 -0.915 23.5-140.1-138.2 162.2 26.0 -5.0 12.6 23 80 A T E -DC 90 30A 18 67,-2.4 67,-1.9 -2,-0.3 2,-0.4 -0.975 15.5-169.7-125.1 143.8 24.3 -6.3 9.5 24 81 A V E > +DC 89 29A 1 5,-2.0 5,-2.1 -2,-0.4 65,-0.2 -0.995 44.9 4.0-131.8 141.1 20.7 -5.3 8.3 25 82 A G T 5S- 0 0 6 63,-2.2 4,-0.1 -2,-0.4 36,-0.1 -0.089 88.3 -44.4 86.3 178.3 18.6 -6.8 5.5 26 83 A S T 5S+ 0 0 28 2,-0.1 36,-2.9 1,-0.1 37,-0.3 -0.987 131.0 29.3-134.2 116.9 18.9 -9.7 3.0 27 84 A P T 5S- 0 0 102 0, 0.0 -1,-0.1 0, 0.0 -3,-0.1 0.632 121.9-102.0 -65.3 157.6 21.5 -10.0 1.6 28 85 A P T 5 - 0 0 90 0, 0.0 2,-0.6 0, 0.0 -3,-0.2 -0.293 29.8-153.6 -60.6 135.8 23.2 -8.5 4.7 29 86 A Q E < -C 24 0A 31 -5,-2.1 -5,-2.0 -4,-0.1 2,-0.3 -0.948 17.6-136.4-107.3 114.4 24.3 -4.8 4.6 30 87 A T E +C 23 0A 53 -2,-0.6 2,-0.3 -7,-0.2 -7,-0.2 -0.597 31.2 167.2 -77.1 133.6 27.2 -4.2 7.0 31 88 A L E -C 22 0A 3 -9,-2.7 -9,-3.0 -2,-0.3 2,-0.5 -0.978 35.3-123.8-141.5 152.7 27.0 -1.0 9.1 32 89 A N E -C 21 0A 2 -2,-0.3 88,-3.3 -11,-0.2 89,-0.8 -0.849 33.5-160.9 -98.1 127.7 28.9 0.4 12.1 33 90 A I E -Ce 20 121A 0 -13,-3.0 -13,-2.5 -2,-0.5 89,-0.3 -0.960 17.2-123.6-124.8 124.0 26.5 1.2 14.9 34 91 A L E -Ce 19 122A 16 87,-3.0 89,-3.5 -2,-0.5 2,-0.7 -0.360 24.7-130.4 -62.0 130.2 27.0 3.5 17.9 35 92 A V E + e 0 123A 1 -17,-3.0 2,-0.5 87,-0.2 -17,-0.4 -0.745 34.4 179.2 -85.1 111.4 26.4 1.6 21.3 36 93 A D E > + e 0 124A 18 87,-2.5 89,-2.8 -2,-0.7 3,-1.0 -0.867 26.2 173.9-124.0 99.5 23.9 3.9 23.1 37 94 A T T 3 S+ 0 0 0 -2,-0.5 166,-0.5 1,-0.2 194,-0.2 0.448 80.6 68.8 -80.1 2.2 22.6 3.1 26.6 38 95 A G T 3 S+ 0 0 14 164,-0.1 2,-0.3 88,-0.1 -1,-0.2 0.231 101.9 37.6-102.6 8.5 21.0 6.5 26.7 39 96 A S < - 0 0 28 -3,-1.0 87,-2.8 84,-0.1 92,-0.1 -0.921 63.8-143.1-150.8 170.3 18.3 6.0 24.0 40 97 A S + 0 0 2 90,-0.4 2,-0.4 -2,-0.3 100,-0.2 0.293 62.8 95.4-130.1 12.8 16.0 3.2 22.9 41 98 A N - 0 0 10 98,-0.1 83,-1.5 89,-0.1 2,-0.7 -0.858 61.1-141.0-105.2 145.1 15.7 3.3 19.0 42 99 A F E +F 123 0A 6 -2,-0.4 62,-2.5 81,-0.2 2,-0.4 -0.900 39.8 169.2 -97.3 109.5 17.7 1.3 16.5 43 100 A A E -Fg 122 104A 0 79,-2.1 79,-3.1 -2,-0.7 2,-0.3 -0.997 12.1-176.4-134.8 127.8 18.1 4.1 13.8 44 101 A V E -Fg 121 105A 0 60,-2.3 62,-3.4 -2,-0.4 77,-0.3 -0.956 36.8 -98.8-126.9 146.2 20.4 4.0 10.8 45 102 A G E + g 0 106A 1 75,-3.1 11,-2.7 -2,-0.3 62,-0.2 -0.379 41.3 172.1 -57.2 128.3 21.4 6.4 8.0 46 103 A A + 0 0 10 60,-2.8 12,-0.2 9,-0.2 -1,-0.1 0.105 57.9 47.4-131.0 19.6 19.2 5.4 5.0 47 104 A A S S- 0 0 26 59,-0.3 -1,-0.1 7,-0.1 9,-0.1 -0.976 99.0 -75.2-154.8 153.4 19.9 8.2 2.6 48 105 A P + 0 0 104 0, 0.0 -2,-0.1 0, 0.0 5,-0.1 -0.214 50.9 171.9 -55.9 141.5 23.1 10.0 1.4 49 106 A H > - 0 0 49 3,-0.4 3,-1.8 -4,-0.1 5,-0.1 -0.971 43.4-116.4-146.9 143.7 24.7 12.3 3.9 50 107 A P T 3 S+ 0 0 117 0, 0.0 -1,-0.0 0, 0.0 0, 0.0 0.772 115.2 47.3 -53.3 -30.2 28.1 14.2 3.6 51 108 A F T 3 S+ 0 0 91 64,-0.1 2,-0.4 62,-0.0 65,-0.3 0.337 98.4 80.7 -96.0 4.6 29.5 12.2 6.7 52 109 A L < - 0 0 21 -3,-1.8 -3,-0.4 1,-0.1 3,-0.1 -0.945 46.9-176.0-113.4 131.3 28.4 8.7 5.6 53 110 A H S S+ 0 0 138 -2,-0.4 2,-0.3 1,-0.2 -1,-0.1 0.450 81.4 19.0-100.6 -1.0 30.3 6.5 3.2 54 111 A R + 0 0 76 -7,-0.1 2,-0.3 -5,-0.1 -1,-0.2 -0.974 66.0 176.3-158.5 158.6 27.5 3.9 3.4 55 112 A Y - 0 0 65 -2,-0.3 2,-0.4 -9,-0.1 -9,-0.2 -0.971 41.7 -76.0-161.0 163.5 23.9 3.6 4.5 56 113 A Y - 0 0 2 -11,-2.7 2,-0.7 -2,-0.3 -31,-0.1 -0.575 36.3-160.4 -70.4 123.7 20.9 1.2 4.6 57 114 A Q > - 0 0 62 -2,-0.4 3,-1.8 1,-0.2 4,-0.3 -0.870 6.2-173.1-110.8 92.2 19.3 0.7 1.2 58 115 A R G > S+ 0 0 40 -2,-0.7 3,-1.5 1,-0.3 6,-0.3 0.818 81.3 62.9 -55.9 -34.5 15.8 -0.7 1.9 59 116 A Q G 3 S+ 0 0 145 1,-0.3 -1,-0.3 3,-0.0 -2,-0.0 0.599 101.2 53.7 -68.2 -14.9 15.1 -1.4 -1.8 60 117 A L G < S+ 0 0 97 -3,-1.8 2,-0.6 -33,-0.0 -1,-0.3 0.425 91.3 88.3 -97.5 -1.7 18.0 -3.9 -1.8 61 118 A S X - 0 0 10 -3,-1.5 3,-1.0 -4,-0.3 -36,-0.1 -0.881 56.6-165.5-104.2 118.4 16.6 -5.9 1.1 62 119 A S T 3 S+ 0 0 104 -36,-2.9 -1,-0.1 -2,-0.6 -4,-0.0 0.697 92.8 50.8 -69.7 -21.2 14.2 -8.7 0.3 63 120 A T T 3 S+ 0 0 29 -37,-0.3 -1,-0.2 25,-0.1 -38,-0.1 0.355 79.3 125.2 -98.2 1.3 13.2 -8.9 4.0 64 121 A Y < - 0 0 54 -3,-1.0 2,-0.4 -6,-0.3 23,-0.2 -0.409 41.1-167.0 -63.0 136.2 12.5 -5.2 4.4 65 122 A R E -H 86 0A 149 21,-2.2 21,-2.3 -2,-0.1 2,-0.5 -0.997 13.8-139.0-129.4 123.7 9.0 -4.5 5.8 66 123 A D E -H 85 0A 83 -2,-0.4 19,-0.2 19,-0.2 18,-0.0 -0.740 10.1-166.4 -86.8 123.9 7.6 -0.9 5.7 67 124 A L E - 0 0 75 17,-1.9 18,-0.2 -2,-0.5 -1,-0.1 0.530 33.0-133.7 -83.1 -7.5 5.6 0.1 8.8 68 125 A R E + 0 0 223 16,-0.5 2,-0.3 1,-0.2 17,-0.1 0.885 66.7 111.7 55.7 46.8 4.2 3.2 6.9 69 126 A K E - 0 0 91 15,-0.5 15,-3.2 2,-0.0 -1,-0.2 -0.984 58.0-138.2-150.4 137.8 4.9 5.6 9.7 70 127 A G E -H 83 0A 50 -2,-0.3 2,-0.4 13,-0.2 13,-0.2 -0.474 11.0-152.6 -91.8 161.2 7.4 8.5 10.2 71 128 A V E -H 82 0A 6 11,-2.3 11,-2.4 -2,-0.2 2,-0.5 -0.997 3.7-164.0-138.0 133.0 9.4 9.2 13.3 72 129 A Y E -H 81 0A 123 -2,-0.4 9,-0.2 9,-0.2 -2,-0.0 -0.985 6.7-178.1-124.2 115.3 10.7 12.7 14.4 73 130 A V E +H 80 0A 16 7,-2.9 7,-1.3 -2,-0.5 2,-0.2 -0.705 4.4 176.6-120.0 80.7 13.4 12.9 17.0 74 131 A P E +H 79 0A 52 0, 0.0 2,-0.3 0, 0.0 5,-0.3 -0.593 11.2 173.9 -80.1 142.3 14.3 16.5 17.9 75 132 A Y E > -H 78 0A 91 3,-3.2 3,-1.1 -2,-0.2 -2,-0.0 -0.838 45.3 -78.3-138.5 176.2 17.0 16.8 20.7 76 133 A T T 3 S+ 0 0 142 -2,-0.3 -1,-0.1 1,-0.2 3,-0.0 0.914 124.5 18.9 -38.4 -70.2 19.0 19.5 22.4 77 134 A Q T 3 S- 0 0 149 34,-0.1 2,-0.3 -3,-0.1 -1,-0.2 0.105 132.4 -29.9 -99.5 22.1 21.7 20.0 19.8 78 135 A G E < -H 75 0A 13 -3,-1.1 -3,-3.2 2,-0.0 2,-0.3 -0.985 58.2-115.6 166.7-156.7 20.1 18.6 16.7 79 136 A K E -HI 74 110A 56 31,-2.5 31,-3.0 -2,-0.3 2,-0.3 -0.984 2.5-150.8-168.7 164.4 17.6 16.0 15.3 80 137 A W E -HI 73 109A 9 -7,-1.3 -7,-2.9 -2,-0.3 2,-0.3 -0.984 13.4-172.3-142.8 147.4 17.0 13.0 13.1 81 138 A E E +HI 72 108A 56 27,-3.0 26,-1.9 -2,-0.3 27,-1.8 -0.984 18.7 136.0-139.2 148.4 13.9 12.1 11.2 82 139 A G E -HI 71 106A 5 -11,-2.4 -11,-2.3 -2,-0.3 2,-0.4 -0.924 45.5 -77.5-169.5-166.4 13.0 8.9 9.4 83 140 A E E -HI 70 105A 81 22,-2.0 22,-3.0 -2,-0.3 -13,-0.2 -0.948 39.1-127.0-119.3 133.0 10.7 6.1 8.3 84 141 A L E + I 0 104A 0 -15,-3.2 -17,-1.9 -2,-0.4 -16,-0.5 -0.545 42.9 134.1 -84.1 143.7 9.8 3.1 10.5 85 142 A G E -HI 66 103A 2 18,-1.5 18,-3.1 -19,-0.2 2,-0.3 -0.926 41.5-115.0-164.0-177.9 10.2 -0.5 9.3 86 143 A T E +HI 65 102A 17 -21,-2.3 -21,-2.2 -2,-0.3 2,-0.3 -0.943 32.0 157.1-129.8 156.2 11.4 -3.9 10.2 87 144 A D E - I 0 101A 0 14,-1.7 14,-2.4 -2,-0.3 2,-0.4 -0.965 48.4 -76.7-164.3 171.6 14.2 -6.2 8.8 88 145 A L E - I 0 100A 50 -2,-0.3 -63,-2.2 12,-0.2 2,-0.4 -0.669 50.1-170.0 -81.6 129.3 16.5 -9.0 9.8 89 146 A V E +DI 24 99A 1 10,-2.9 10,-2.7 -2,-0.4 2,-0.3 -0.971 10.1 174.1-127.4 139.0 19.4 -7.9 12.0 90 147 A S E -D 23 0A 26 -67,-1.9 -67,-2.4 -2,-0.4 8,-0.1 -0.886 27.1-140.1-137.7 162.6 22.6 -9.7 13.1 91 148 A I > - 0 0 8 6,-0.5 3,-0.8 4,-0.5 -69,-0.2 -0.950 14.7-157.3-124.5 100.9 25.8 -8.8 15.1 92 149 A P T 3 S+ 0 0 47 0, 0.0 2,-0.9 0, 0.0 -1,-0.1 0.886 95.0 39.8 -50.3 -44.0 28.7 -10.5 13.3 93 150 A H T 3 S+ 0 0 99 -72,-0.4 -84,-0.1 -84,-0.1 3,-0.1 -0.553 116.2 68.4-102.6 61.1 30.9 -10.4 16.5 94 151 A G S < S- 0 0 0 -2,-0.9 2,-0.1 -3,-0.8 -87,-0.1 -0.623 99.5 -26.6-149.8-155.8 28.0 -11.2 18.7 95 152 A P - 0 0 19 0, 0.0 2,-1.9 0, 0.0 -4,-0.5 -0.416 66.2-113.8 -67.5 149.9 25.5 -14.0 19.6 96 153 A N S S+ 0 0 125 -6,-0.1 2,-0.3 -2,-0.1 -6,-0.0 -0.380 80.3 106.5 -86.7 65.0 25.1 -16.3 16.6 97 154 A V - 0 0 47 -2,-1.9 -6,-0.5 -6,-0.2 2,-0.4 -0.953 57.4-145.4-139.0 156.5 21.4 -15.3 16.0 98 155 A T - 0 0 82 -2,-0.3 2,-0.3 -8,-0.1 -8,-0.2 -0.984 23.5-172.0-123.3 130.4 19.4 -13.3 13.5 99 156 A V E - I 0 89A 3 -10,-2.7 -10,-2.9 -2,-0.4 2,-0.7 -0.916 28.2-122.3-124.8 155.1 16.4 -11.3 14.7 100 157 A R E + I 0 88A 50 -2,-0.3 2,-0.3 -12,-0.2 -12,-0.2 -0.861 47.9 169.7 -93.1 119.4 13.5 -9.3 13.2 101 158 A A E - I 0 87A 3 -14,-2.4 -14,-1.7 -2,-0.7 2,-0.2 -0.901 39.4 -97.7-130.3 160.2 13.8 -5.8 14.7 102 159 A N E - I 0 86A 28 36,-0.5 2,-0.4 -2,-0.3 -16,-0.3 -0.489 38.6-168.8 -72.3 141.7 12.4 -2.4 14.2 103 160 A I E - I 0 85A 4 -18,-3.1 -18,-1.5 -2,-0.2 2,-0.7 -0.989 16.8-149.1-135.8 127.0 14.6 -0.0 12.2 104 161 A A E -gI 43 84A 1 -62,-2.5 -60,-2.3 -2,-0.4 2,-0.8 -0.869 18.7-146.6 -94.1 113.4 14.2 3.7 11.9 105 162 A A E -gI 44 83A 2 -22,-3.0 -22,-2.0 -2,-0.7 2,-0.5 -0.773 15.6-137.2 -84.6 105.0 15.5 4.5 8.4 106 163 A I E +gI 45 82A 4 -62,-3.4 -60,-2.8 -2,-0.8 -59,-0.3 -0.591 35.3 163.7 -72.3 119.1 17.1 8.0 8.8 107 164 A T E + 0 0 44 -26,-1.9 2,-0.3 -2,-0.5 -25,-0.2 0.594 67.8 20.4-107.7 -20.9 16.2 10.2 5.8 108 165 A E E + I 0 81A 116 -27,-1.8 -27,-3.0 2,-0.0 -1,-0.3 -0.983 66.8 164.6-151.3 141.5 17.0 13.7 7.3 109 166 A S E - 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