==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=27-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER OXIDO-REDUCTASE 25-JAN-95 1DLS . COMPND 2 MOLECULE: DIHYDROFOLATE REDUCTASE; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR V.CODY,N.GALITSKY,J.R.LUFT,W.PANGBORN . 187 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10077.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 115 61.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 27 14.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 24 12.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 3 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 14 7.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 16 8.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 30 16.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 2 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 2 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 1 A V 0 0 115 0, 0.0 2,-0.3 0, 0.0 110,-0.0 0.000 360.0 360.0 360.0 78.9 8.0 21.0 2.2 2 2 A G - 0 0 47 110,-0.0 109,-0.2 0, 0.0 2,-0.1 -0.846 360.0 -20.8-178.0-164.1 9.1 20.5 -1.3 3 3 A S - 0 0 49 -2,-0.3 109,-2.7 1,-0.0 2,-0.5 -0.308 52.5-142.2 -63.9 152.6 10.8 17.6 -2.9 4 4 A L E +a 112 0A 24 126,-0.4 128,-1.3 107,-0.2 2,-0.3 -0.946 31.4 167.3-118.7 120.1 12.6 14.9 -1.0 5 5 A N E -ab 113 132A 3 107,-2.3 109,-2.5 -2,-0.5 2,-0.4 -0.983 29.0-147.8-136.6 152.1 15.8 13.6 -2.7 6 6 A C E -ab 114 133A 1 126,-2.1 128,-2.8 -2,-0.3 2,-0.4 -0.870 14.5-167.8-113.4 140.3 18.8 11.5 -2.0 7 7 A I E + b 0 134A 0 107,-2.3 2,-0.3 -2,-0.4 128,-0.2 -0.999 16.9 158.5-128.1 137.2 22.1 12.3 -3.7 8 8 A V E - b 0 135A 2 126,-2.5 128,-2.4 -2,-0.4 2,-0.5 -0.978 35.7-139.1-153.5 155.8 25.1 9.8 -3.6 9 9 A A E - b 0 136A 3 -2,-0.3 2,-0.3 126,-0.2 128,-0.2 -0.994 31.7-173.3-119.6 117.9 28.3 8.9 -5.5 10 10 A V E - b 0 137A 0 126,-2.8 128,-3.2 -2,-0.5 6,-0.2 -0.953 18.6-137.2-121.6 132.5 28.8 5.1 -5.7 11 11 A S > - 0 0 2 4,-1.9 3,-2.0 -2,-0.3 130,-0.2 -0.208 44.6 -92.6 -78.2 168.1 31.7 2.9 -7.0 12 12 A Q T 3 S+ 0 0 131 128,-2.0 129,-0.2 126,-0.3 127,-0.1 0.875 129.8 51.4 -51.0 -42.5 30.9 -0.2 -9.1 13 13 A N T 3 S- 0 0 53 127,-0.3 -1,-0.3 129,-0.1 131,-0.1 0.091 124.2-104.1 -88.4 19.8 30.8 -2.4 -6.0 14 14 A M < + 0 0 48 -3,-2.0 134,-2.0 1,-0.2 2,-0.3 0.652 68.7 152.4 69.6 29.8 28.4 0.1 -4.3 15 15 A G E +I 147 0B 0 132,-0.2 -4,-1.9 127,-0.1 132,-0.3 -0.657 21.9 170.4 -87.3 150.8 31.0 1.7 -2.0 16 16 A I E + 0 0 28 130,-2.9 2,-0.3 1,-0.3 131,-0.2 0.505 63.4 22.2-129.4 -9.3 30.6 5.3 -0.7 17 17 A G E -I 146 0B 7 129,-1.4 128,-2.4 5,-0.2 129,-1.2 -0.990 43.3-173.2-158.5 160.9 33.3 5.6 1.9 18 18 A K B > S-J 21 0C 74 3,-2.6 3,-1.5 -2,-0.3 126,-0.1 -0.931 80.7 -17.9-155.0 120.2 36.6 4.3 3.2 19 19 A N T 3 S- 0 0 134 -2,-0.3 3,-0.1 1,-0.3 125,-0.0 0.826 129.0 -45.3 44.4 45.2 38.2 5.5 6.6 20 20 A G T 3 S+ 0 0 31 1,-0.2 2,-0.3 0, 0.0 -1,-0.3 0.665 126.8 76.1 83.0 8.1 36.1 8.6 6.8 21 21 A D B < S-J 18 0C 75 -3,-1.5 -3,-2.6 39,-0.0 -1,-0.2 -0.878 90.3 -89.0-138.6-178.2 36.5 9.8 3.2 22 22 A Y - 0 0 29 -2,-0.3 -5,-0.2 -5,-0.2 -6,-0.1 -0.651 44.7-117.8 -91.0 156.6 35.1 8.8 -0.2 23 23 A P S S+ 0 0 25 0, 0.0 120,-0.1 0, 0.0 -1,-0.1 0.660 84.9 61.5 -71.9 -25.1 37.2 6.0 -1.8 24 24 A W S S- 0 0 13 1,-0.2 -2,-0.2 118,-0.1 3,-0.1 -0.514 94.8 -83.1 -97.6 170.6 38.4 7.7 -5.0 25 25 A P - 0 0 51 0, 0.0 -1,-0.2 0, 0.0 0, 0.0 -0.209 68.5 -76.1 -61.8 150.5 40.6 10.7 -5.7 26 26 A P - 0 0 44 0, 0.0 2,-0.6 0, 0.0 0, 0.0 -0.300 43.2-155.9 -51.3 130.5 38.6 14.1 -5.6 27 27 A L >> - 0 0 3 1,-0.1 4,-2.1 -3,-0.1 3,-0.8 -0.967 3.5-161.8-111.1 99.1 36.5 14.5 -8.9 28 28 A R H 3> S+ 0 0 138 -2,-0.6 4,-1.5 1,-0.2 -1,-0.1 0.663 88.1 46.3 -59.5 -31.3 36.0 18.3 -9.2 29 29 A N H 3> S+ 0 0 69 2,-0.2 4,-1.3 3,-0.2 -1,-0.2 0.587 109.4 55.0 -81.1 -20.2 33.1 18.2 -11.6 30 30 A E H <> S+ 0 0 3 -3,-0.8 4,-2.4 2,-0.2 -2,-0.2 0.877 113.3 43.1 -73.0 -45.7 31.4 15.5 -9.5 31 31 A F H X S+ 0 0 22 -4,-2.1 4,-2.6 2,-0.2 -2,-0.2 0.866 112.2 53.6 -62.4 -40.3 31.8 18.0 -6.6 32 32 A R H X S+ 0 0 152 -4,-1.5 4,-2.4 2,-0.2 -1,-0.2 0.892 111.5 45.0 -58.3 -44.6 30.6 20.9 -8.9 33 33 A Y H X S+ 0 0 4 -4,-1.3 4,-2.9 2,-0.2 5,-0.3 0.954 112.4 50.9 -62.0 -52.7 27.5 18.9 -9.8 34 34 A F H X S+ 0 0 0 -4,-2.4 4,-2.4 2,-0.2 5,-0.2 0.950 112.4 49.1 -51.9 -46.4 26.8 17.9 -6.1 35 35 A Q H X S+ 0 0 71 -4,-2.6 4,-2.4 1,-0.2 5,-0.3 0.919 113.6 44.0 -59.9 -50.6 27.1 21.6 -5.1 36 36 A R H X S+ 0 0 96 -4,-2.4 4,-2.2 2,-0.2 -1,-0.2 0.921 114.5 49.0 -68.3 -41.4 24.8 22.9 -7.9 37 37 A M H < S+ 0 0 25 -4,-2.9 -2,-0.2 -5,-0.2 -1,-0.2 0.941 117.9 39.6 -61.5 -47.3 22.1 20.2 -7.3 38 38 A T H < S+ 0 0 0 -4,-2.4 10,-0.2 -5,-0.3 -2,-0.2 0.838 120.2 44.8 -72.6 -30.6 22.0 20.6 -3.6 39 39 A T H < S+ 0 0 42 -4,-2.4 2,-0.4 -5,-0.2 9,-0.4 0.851 89.0 96.5 -83.4 -32.5 22.3 24.5 -3.6 40 40 A T < - 0 0 88 -4,-2.2 2,-0.5 -5,-0.3 71,-0.1 -0.228 57.1-161.7 -74.3 118.8 19.8 25.3 -6.4 41 41 A S - 0 0 28 -2,-0.4 4,-0.1 5,-0.2 -1,-0.1 -0.798 14.3-149.8-100.1 140.5 16.4 26.2 -5.2 42 42 A S S S+ 0 0 105 -2,-0.5 -1,-0.1 2,-0.1 2,-0.1 0.612 79.8 52.2 -72.2 -33.3 13.4 26.0 -7.5 43 43 A V S S- 0 0 72 1,-0.0 2,-0.5 0, 0.0 3,-0.2 -0.248 95.0 -92.9-101.2-175.2 11.4 28.8 -5.9 44 44 A E S S+ 0 0 182 1,-0.2 3,-0.1 -2,-0.1 -2,-0.1 -0.952 101.8 7.2-112.6 134.5 12.5 32.4 -5.0 45 45 A G S S+ 0 0 80 -2,-0.5 2,-0.3 1,-0.3 -1,-0.2 0.659 101.8 116.2 73.6 16.2 13.9 33.3 -1.7 46 46 A K - 0 0 65 -3,-0.2 2,-0.3 63,-0.0 -1,-0.3 -0.784 47.9-157.3-115.2 162.3 14.0 29.7 -0.5 47 47 A Q E -c 109 0A 80 61,-2.9 63,-1.8 -2,-0.3 2,-0.3 -0.939 21.3-115.3-129.9 155.7 17.1 27.6 0.3 48 48 A N E - 0 0 0 21,-0.4 23,-2.0 -9,-0.4 2,-0.4 -0.621 22.7-131.0 -92.4 154.9 17.4 23.9 0.3 49 49 A L E -cd 112 71A 0 62,-2.2 64,-2.7 -2,-0.3 2,-0.5 -0.835 14.4-154.9-102.4 133.6 18.0 21.8 3.5 50 50 A V E -cd 113 72A 0 21,-3.3 23,-2.9 -2,-0.4 2,-0.4 -0.965 5.9-160.9-110.8 126.3 20.8 19.2 3.5 51 51 A I E +cd 114 73A 0 62,-2.8 64,-2.8 -2,-0.5 65,-0.4 -0.952 18.9 163.7-110.2 132.8 20.5 16.3 6.0 52 52 A M E - d 0 74A 0 21,-1.9 23,-2.6 -2,-0.4 65,-0.3 -0.955 34.8-118.8-146.9 148.5 23.6 14.3 6.9 53 53 A G E > - d 0 75A 12 63,-1.6 4,-2.3 -2,-0.3 23,-0.1 -0.330 43.3 -99.0 -79.5 173.3 24.7 11.8 9.7 54 54 A K H > S+ 0 0 64 21,-0.9 4,-2.7 1,-0.2 5,-0.2 0.904 118.9 53.7 -67.5 -42.4 27.6 12.8 11.9 55 55 A K H > S+ 0 0 130 2,-0.2 4,-1.1 1,-0.2 -1,-0.2 0.902 110.2 51.1 -62.0 -35.5 30.4 10.9 10.3 56 56 A T H >> S+ 0 0 20 2,-0.2 3,-1.0 1,-0.2 4,-0.6 0.968 107.5 51.9 -66.1 -44.1 29.4 12.5 6.9 57 57 A W H >< S+ 0 0 0 -4,-2.3 3,-1.6 1,-0.3 -2,-0.2 0.969 111.4 48.6 -55.4 -54.1 29.5 16.0 8.5 58 58 A F H 3< S+ 0 0 105 -4,-2.7 -1,-0.3 1,-0.3 -2,-0.2 0.745 101.6 62.8 -68.4 -8.0 33.0 15.3 9.9 59 59 A S H << S+ 0 0 28 -4,-1.1 -1,-0.3 -3,-1.0 -2,-0.2 0.545 83.9 91.5 -87.8 -8.1 34.3 14.0 6.5 60 60 A I S << S- 0 0 2 -3,-1.6 5,-0.1 -4,-0.6 2,-0.0 -0.779 94.8-101.5 -83.8 142.7 33.8 17.4 4.8 61 61 A P > - 0 0 68 0, 0.0 3,-2.3 0, 0.0 4,-0.1 -0.327 26.7-121.0 -61.1 142.2 36.8 19.6 5.1 62 62 A E G > S+ 0 0 134 1,-0.3 3,-1.8 2,-0.2 -2,-0.0 0.823 112.4 60.5 -51.5 -41.7 36.5 22.2 7.9 63 63 A K G 3 S+ 0 0 204 1,-0.3 -1,-0.3 0, 0.0 -3,-0.0 0.827 106.6 47.6 -56.8 -39.2 37.0 25.0 5.3 64 64 A N G < S+ 0 0 69 -3,-2.3 -1,-0.3 124,-0.1 -2,-0.2 0.144 89.8 137.5 -89.3 14.7 33.9 23.8 3.5 65 65 A R < + 0 0 52 -3,-1.8 21,-0.1 -4,-0.1 2,-0.1 -0.938 61.5 30.2-111.8 129.9 31.7 23.5 6.7 66 66 A P S S- 0 0 44 0, 0.0 2,-0.5 0, 0.0 20,-0.1 0.592 101.9-114.3 -70.9 160.3 28.9 24.4 6.8 67 67 A L > - 0 0 1 1,-0.1 3,-1.2 -2,-0.1 -2,-0.1 -0.557 44.8-114.1 -64.4 113.7 28.0 23.7 3.1 68 68 A K T 3 S+ 0 0 154 -2,-0.5 -1,-0.1 1,-0.2 3,-0.1 -0.116 89.6 16.7 -59.7 140.0 27.4 27.3 1.9 69 69 A G T 3 S+ 0 0 40 1,-0.2 -21,-0.4 -3,-0.0 2,-0.3 0.560 109.0 90.3 78.7 8.8 24.0 28.5 0.7 70 70 A R S < S- 0 0 5 -3,-1.2 2,-0.5 -23,-0.1 -21,-0.2 -0.961 82.1-112.5-133.0 152.0 22.2 25.6 2.3 71 71 A I E -d 49 0A 13 -23,-2.0 -21,-3.3 -2,-0.3 2,-0.7 -0.748 39.0-148.0 -81.2 116.3 20.6 24.9 5.7 72 72 A N E -d 50 0A 0 -2,-0.5 15,-1.7 -23,-0.2 16,-1.5 -0.872 18.6-179.2 -96.5 112.0 22.9 22.2 7.2 73 73 A L E -de 51 88A 0 -23,-2.9 -21,-1.9 -2,-0.7 2,-0.4 -0.962 9.8-157.9-113.9 135.2 21.3 19.7 9.5 74 74 A V E -de 52 89A 0 14,-2.5 16,-2.1 -2,-0.5 2,-0.4 -0.848 8.8-142.2-108.2 141.8 23.2 16.9 11.2 75 75 A L E +de 53 90A 22 -23,-2.6 -21,-0.9 -2,-0.4 2,-0.3 -0.828 37.7 139.3-102.5 129.6 21.6 13.6 12.6 76 76 A S - 0 0 12 14,-2.5 -2,-0.0 -2,-0.4 16,-0.0 -0.895 40.5-163.0-165.3 141.9 22.9 12.2 15.8 77 77 A R S S+ 0 0 179 -2,-0.3 14,-0.1 1,-0.0 -1,-0.1 0.511 95.2 50.2-102.2 -5.3 21.5 10.6 18.9 78 78 A E S S+ 0 0 155 0, 0.0 -2,-0.1 0, 0.0 13,-0.0 0.826 89.1 85.9 -99.8 -46.0 24.7 11.2 20.9 79 79 A L - 0 0 48 1,-0.1 -3,-0.1 -4,-0.0 10,-0.0 -0.322 58.2-157.0 -65.7 154.1 25.5 14.9 20.4 80 80 A K S S+ 0 0 169 1,-0.2 -1,-0.1 2,-0.1 9,-0.1 0.572 77.2 13.5-103.1 -25.0 23.8 17.5 22.6 81 81 A E S S- 0 0 151 7,-0.1 -1,-0.2 3,-0.0 3,-0.1 -0.914 99.5 -75.4-146.4 162.9 24.0 20.5 20.3 82 82 A P - 0 0 44 0, 0.0 3,-0.1 0, 0.0 7,-0.1 -0.379 59.3-102.6 -62.0 146.5 24.9 20.9 16.5 83 83 A P > - 0 0 15 0, 0.0 3,-2.0 0, 0.0 -9,-0.1 -0.180 59.9 -68.2 -60.1 166.4 28.6 20.5 15.9 84 84 A Q T 3 S+ 0 0 167 1,-0.3 3,-0.1 -3,-0.1 -3,-0.0 -0.386 127.0 18.7 -59.8 128.8 30.4 23.8 15.4 85 85 A G T 3 S+ 0 0 33 1,-0.4 -1,-0.3 -3,-0.1 2,-0.1 -0.013 97.4 117.7 95.5 -19.9 29.2 25.3 12.0 86 86 A A < - 0 0 16 -3,-2.0 -1,-0.4 1,-0.1 -13,-0.1 -0.492 54.4-151.6 -81.6 144.7 26.0 23.2 11.8 87 87 A H S S+ 0 0 91 -15,-1.7 2,-0.3 1,-0.2 -14,-0.2 0.816 72.5 9.7 -87.8 -31.7 22.6 24.9 11.8 88 88 A F E -e 73 0A 48 -16,-1.5 -14,-2.5 -7,-0.1 2,-0.4 -0.969 55.6-152.0-152.9 150.4 20.4 22.2 13.4 89 89 A L E -e 74 0A 43 -2,-0.3 2,-0.3 -16,-0.2 -14,-0.2 -0.996 16.3-175.4-125.6 131.0 20.7 18.8 15.1 90 90 A S E -e 75 0A 10 -16,-2.1 -14,-2.5 -2,-0.4 3,-0.1 -0.928 24.4-146.3-126.0 151.5 18.0 16.1 14.9 91 91 A R S S+ 0 0 174 -2,-0.3 2,-0.3 -16,-0.2 -16,-0.1 0.543 83.3 14.5 -90.9 -14.3 17.7 12.8 16.6 92 92 A S S > S- 0 0 26 1,-0.1 4,-2.0 -16,-0.0 5,-0.2 -0.985 74.5-111.8-156.3 157.0 15.9 11.1 13.8 93 93 A L H > S+ 0 0 2 -2,-0.3 4,-2.5 1,-0.2 5,-0.1 0.915 116.9 54.8 -63.4 -32.9 15.0 11.5 10.1 94 94 A D H > S+ 0 0 67 1,-0.2 4,-3.5 2,-0.2 5,-0.2 0.911 109.1 46.5 -66.7 -38.9 11.3 11.9 11.1 95 95 A D H > S+ 0 0 66 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.855 109.2 55.4 -67.5 -36.1 12.1 14.7 13.4 96 96 A A H X S+ 0 0 0 -4,-2.0 4,-0.6 1,-0.2 -2,-0.2 0.928 115.2 39.2 -61.7 -41.7 14.3 16.3 10.8 97 97 A L H >< S+ 0 0 33 -4,-2.5 3,-1.2 -5,-0.2 4,-0.4 0.926 109.5 58.2 -76.7 -37.5 11.4 16.3 8.4 98 98 A K H >< S+ 0 0 100 -4,-3.5 3,-1.4 1,-0.2 -2,-0.2 0.867 102.3 60.8 -56.8 -30.4 8.8 17.3 11.2 99 99 A L H >< S+ 0 0 27 -4,-2.0 3,-1.3 1,-0.3 6,-0.6 0.805 90.5 64.2 -63.3 -30.7 11.1 20.4 11.6 100 100 A T T << S+ 0 0 9 -3,-1.2 -1,-0.3 -4,-0.6 9,-0.2 0.718 98.3 58.1 -66.6 -22.8 10.5 21.6 8.0 101 101 A E T < S+ 0 0 127 -3,-1.4 -1,-0.3 -4,-0.4 -2,-0.2 0.256 80.8 105.5 -94.1 3.9 6.9 22.0 9.0 102 102 A Q S <> S- 0 0 70 -3,-1.3 4,-4.4 1,-0.1 3,-0.4 -0.739 84.5-120.8 -84.4 134.1 7.8 24.5 11.9 103 103 A P H > S+ 0 0 100 0, 0.0 4,-1.0 0, 0.0 -1,-0.1 0.754 111.8 70.1 -44.8 -34.0 6.8 28.0 10.9 104 104 A E H 4 S+ 0 0 106 1,-0.2 3,-0.4 2,-0.2 4,-0.1 0.967 120.9 9.4 -45.0 -74.5 10.5 28.6 11.4 105 105 A L H >> S+ 0 0 6 -6,-0.6 3,-2.4 -3,-0.4 4,-1.7 0.727 107.3 92.6 -84.9 -26.1 11.6 26.7 8.4 106 106 A A H 3< S+ 0 0 35 -4,-4.4 -1,-0.2 1,-0.3 -2,-0.2 0.703 96.4 37.0 -42.7 -33.8 8.2 26.2 6.8 107 107 A N T 3< S+ 0 0 100 -4,-1.0 -1,-0.3 -3,-0.4 -2,-0.1 0.458 115.9 50.5 -99.6 -8.7 8.7 29.3 4.8 108 108 A K T <4 S+ 0 0 106 -3,-2.4 -61,-2.9 -8,-0.1 2,-0.5 0.625 89.2 83.8-102.5 -25.8 12.4 29.1 4.0 109 109 A V E < + c 0 47A 2 -4,-1.7 -61,-0.2 -63,-0.2 3,-0.1 -0.799 37.5 171.4 -95.4 136.4 13.0 25.7 2.6 110 110 A D E + 0 0 13 -63,-1.8 2,-0.2 -2,-0.5 -1,-0.2 0.852 66.8 6.5 -93.0 -97.2 12.6 24.4 -0.9 111 111 A M E - 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