==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=18-JAN-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE/TRANSFERASE INHIBITOR 06-FEB-12 4DLI . COMPND 2 MOLECULE: MITOGEN-ACTIVATED PROTEIN KINASE 14; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR C.GRUETTER,M.GETLIK,J.R.SIMARD,D.RAUH . 334 4 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 17116.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 210 62.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 43 12.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 24 7.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 43 12.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 92 27.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 1 0 0 0 1 1 0 1 1 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 1 2 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 5 A R 0 0 148 0, 0.0 3,-0.1 0, 0.0 88,-0.0 0.000 360.0 360.0 360.0 129.9 -24.0 3.5 -7.3 2 6 A P - 0 0 74 0, 0.0 2,-0.4 0, 0.0 0, 0.0 -0.291 360.0 -97.9 -69.0 160.9 -23.8 4.8 -10.8 3 7 A T - 0 0 88 -2,-0.0 15,-2.3 2,-0.0 2,-0.3 -0.701 44.3-152.9 -75.0 133.5 -26.2 3.9 -13.6 4 8 A F E -A 17 0A 25 -2,-0.4 2,-0.3 13,-0.2 11,-0.0 -0.782 7.8-159.0-106.1 151.2 -24.6 1.1 -15.7 5 9 A Y E -A 16 0A 58 11,-2.7 11,-2.2 -2,-0.3 2,-0.3 -0.961 8.7-139.7-129.3 155.0 -25.2 0.3 -19.3 6 10 A R E +A 15 0A 158 -2,-0.3 2,-0.3 9,-0.2 9,-0.2 -0.851 24.8 158.1-114.7 143.8 -24.5 -2.9 -21.3 7 11 A Q E -A 14 0A 58 7,-2.0 7,-2.8 -2,-0.3 2,-0.6 -0.986 37.6-114.3-155.0 161.0 -23.2 -3.6 -24.8 8 12 A E E -A 13 0A 148 -2,-0.3 2,-0.5 5,-0.2 5,-0.2 -0.865 28.1-176.4 -98.9 124.9 -21.5 -6.3 -26.8 9 13 A L E > -A 12 0A 21 3,-2.6 3,-2.1 -2,-0.6 15,-0.1 -0.952 69.1 -37.9-123.4 110.7 -18.0 -5.6 -27.9 10 14 A N T 3 S- 0 0 142 -2,-0.5 -1,-0.1 1,-0.3 3,-0.1 0.882 128.6 -33.1 39.0 63.3 -16.4 -8.2 -30.2 11 15 A K T 3 S+ 0 0 83 1,-0.2 -1,-0.3 0, 0.0 2,-0.3 -0.066 118.5 103.0 93.1 -27.9 -18.0 -11.2 -28.4 12 16 A T E < -A 9 0A 36 -3,-2.1 -3,-2.6 1,-0.0 2,-0.9 -0.638 66.9-130.8 -99.4 145.0 -18.1 -9.8 -24.8 13 17 A I E -A 8 0A 88 -2,-0.3 2,-0.5 -5,-0.2 -5,-0.2 -0.778 27.8-165.7 -85.8 99.9 -20.8 -8.3 -22.6 14 18 A W E -A 7 0A 2 -7,-2.8 -7,-2.0 -2,-0.9 2,-0.5 -0.757 8.7-175.2 -88.5 125.3 -19.4 -5.0 -21.2 15 19 A E E +A 6 0A 47 -2,-0.5 -9,-0.2 -9,-0.2 -2,-0.0 -0.945 21.0 160.3-121.7 107.4 -21.4 -3.5 -18.3 16 20 A V E -A 5 0A 0 -11,-2.2 -11,-2.7 -2,-0.5 -2,-0.0 -0.879 43.6 -90.9-130.8 152.9 -19.9 -0.1 -17.4 17 21 A P E > -A 4 0A 5 0, 0.0 3,-2.1 0, 0.0 -13,-0.2 -0.303 40.8-114.2 -59.3 149.0 -20.9 3.2 -15.5 18 22 A E T 3 S+ 0 0 107 -15,-2.3 21,-0.1 1,-0.3 -14,-0.1 0.768 110.1 80.4 -59.7 -30.0 -22.5 5.9 -17.7 19 23 A R T 3 S+ 0 0 48 -16,-0.3 20,-2.9 1,-0.1 2,-0.7 0.815 83.3 68.6 -36.6 -43.6 -19.3 7.9 -17.0 20 24 A Y E < S+B 38 0B 0 -3,-2.1 2,-0.2 18,-0.2 18,-0.2 -0.786 70.5 176.2 -96.2 115.3 -17.5 5.9 -19.7 21 25 A Q E +B 37 0B 68 16,-2.8 16,-2.9 -2,-0.7 -2,-0.0 -0.680 49.1 24.6-117.1 166.6 -18.7 6.6 -23.2 22 26 A N E S- 0 0 123 -2,-0.2 -1,-0.2 14,-0.2 2,-0.1 0.878 71.7-161.0 45.6 54.6 -17.8 5.6 -26.8 23 27 A L E + 0 0 16 -3,-0.2 13,-0.2 13,-0.1 -1,-0.2 -0.399 12.7 179.6 -62.4 137.0 -16.2 2.3 -25.9 24 28 A S E -B 35 0B 65 11,-1.9 11,-2.9 -2,-0.1 -15,-0.0 -0.900 28.3-118.8-149.2 111.1 -13.9 1.1 -28.8 25 29 A P E +B 34 0B 51 0, 0.0 9,-0.3 0, 0.0 3,-0.1 -0.146 31.3 172.3 -57.3 139.9 -11.9 -2.2 -28.6 26 30 A V E - 0 0 87 7,-2.7 2,-0.2 1,-0.4 8,-0.2 0.495 60.2 -33.6-124.6 -11.0 -8.1 -1.8 -28.8 27 31 A G E B 33 0B 39 6,-1.1 6,-2.8 0, 0.0 -1,-0.4 -0.789 360.0 360.0 161.1 155.3 -6.9 -5.3 -28.1 28 32 A S 0 0 137 4,-0.2 4,-0.3 -2,-0.2 6,-0.0 -0.991 360.0 360.0-126.6 360.0 -7.4 -8.6 -26.1 29 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 30 35 A Y 0 0 109 0, 0.0 21,-1.0 0, 0.0 2,-0.2 0.000 360.0 360.0 360.0 -48.1 -5.7 -12.0 -19.2 31 36 A G E - C 0 50B 16 19,-0.3 2,-0.2 2,-0.0 19,-0.2 -0.611 360.0 -84.1 136.6 170.1 -8.6 -9.8 -20.5 32 37 A S E - C 0 49B 18 17,-1.2 17,-2.4 -4,-0.3 2,-0.4 -0.707 28.9-143.2-112.9 160.8 -9.6 -7.2 -23.2 33 38 A V E -BC 27 48B 38 -6,-2.8 -7,-2.7 -2,-0.2 -6,-1.1 -0.942 9.4-169.8-128.6 138.3 -9.3 -3.4 -23.4 34 39 A C E -BC 25 47B 2 13,-2.3 13,-2.9 -2,-0.4 2,-0.3 -0.972 22.5-130.1-122.6 140.3 -11.5 -0.6 -24.8 35 40 A A E +BC 24 46B 17 -11,-2.9 -11,-1.9 -2,-0.4 2,-0.3 -0.650 38.2 176.9 -73.5 145.1 -10.7 3.0 -25.3 36 41 A A E - C 0 45B 4 9,-2.2 9,-2.8 -2,-0.3 2,-0.6 -0.982 35.5-116.7-147.0 158.4 -13.4 5.3 -23.8 37 42 A F E -BC 21 44B 87 -16,-2.9 -16,-2.8 -2,-0.3 2,-0.9 -0.881 28.7-143.2 -91.3 124.1 -14.2 8.9 -23.2 38 43 A D E >>> -BC 20 43B 1 5,-2.7 4,-2.7 -2,-0.6 3,-1.3 -0.819 9.3-162.9 -91.3 107.6 -14.3 9.6 -19.5 39 44 A T T 345S+ 0 0 75 -20,-2.9 -1,-0.1 -2,-0.9 -19,-0.1 0.669 84.3 62.5 -69.2 -15.4 -17.1 12.1 -19.1 40 45 A K T 345S+ 0 0 126 -21,-0.2 -1,-0.3 1,-0.1 -20,-0.1 0.769 122.8 14.3 -79.7 -27.6 -15.9 13.0 -15.7 41 46 A T T <45S- 0 0 44 -3,-1.3 -2,-0.2 2,-0.2 -1,-0.1 0.557 93.3-122.5-123.6 -16.2 -12.6 14.4 -16.8 42 47 A G T <5S+ 0 0 45 -4,-2.7 2,-0.3 1,-0.3 -3,-0.2 0.557 72.2 124.9 75.4 13.2 -12.8 14.8 -20.6 43 48 A L E < -C 38 0B 74 -5,-0.6 -5,-2.7 -6,-0.0 2,-0.3 -0.715 67.2-112.1-102.9 152.1 -9.8 12.5 -21.0 44 49 A R E -C 37 0B 197 -2,-0.3 59,-1.6 -7,-0.2 2,-0.3 -0.652 42.3-171.3 -76.7 138.8 -9.5 9.3 -23.1 45 50 A V E -CD 36 102B 0 -9,-2.8 -9,-2.2 -2,-0.3 2,-0.5 -0.869 25.6-124.5-131.7 158.7 -9.1 6.2 -20.9 46 51 A A E -CD 35 101B 12 55,-3.1 55,-2.3 -2,-0.3 2,-0.5 -0.933 23.3-163.5-100.2 129.2 -8.4 2.5 -21.2 47 52 A V E -CD 34 100B 0 -13,-2.9 -13,-2.3 -2,-0.5 2,-0.6 -0.973 4.9-164.0-113.2 121.4 -11.0 0.2 -19.6 48 53 A K E -CD 33 99B 33 51,-3.4 51,-2.4 -2,-0.5 2,-0.6 -0.922 6.4-158.9-110.3 119.1 -9.8 -3.4 -19.0 49 54 A K E -CD 32 98B 19 -17,-2.4 -17,-1.2 -2,-0.6 49,-0.2 -0.868 24.0-129.8 -92.6 119.3 -12.4 -6.1 -18.4 50 55 A L E -C 31 0B 6 47,-2.7 2,-0.5 -2,-0.6 47,-0.3 -0.435 16.6-128.9 -70.8 140.9 -10.7 -9.0 -16.6 51 56 A S S S- 0 0 57 -21,-1.0 -1,-0.1 1,-0.2 45,-0.0 -0.823 79.0 -22.7 -91.7 122.9 -11.3 -12.4 -18.2 52 57 A R S > S- 0 0 165 -2,-0.5 3,-1.6 1,-0.1 4,-0.2 0.885 76.4-179.3 46.3 53.1 -12.4 -15.2 -15.7 53 58 A P T 3 S+ 0 0 1 0, 0.0 10,-0.4 0, 0.0 11,-0.2 0.721 75.5 28.8 -59.8 -23.7 -10.9 -13.2 -12.8 54 59 A F T 3 S+ 0 0 13 41,-0.3 -2,-0.1 1,-0.1 267,-0.1 -0.021 80.1 117.3-129.2 30.1 -12.0 -15.9 -10.2 55 60 A Q S < S+ 0 0 105 -3,-1.6 2,-0.3 1,-0.1 -1,-0.1 0.659 84.0 9.8 -79.3 -17.1 -12.0 -19.1 -12.1 56 61 A S S > S- 0 0 40 -4,-0.2 4,-3.0 -3,-0.1 5,-0.2 -0.954 81.6-102.2-148.9 166.9 -9.2 -20.8 -10.1 57 62 A I H > S+ 0 0 74 -2,-0.3 4,-2.6 1,-0.2 5,-0.2 0.867 125.4 50.8 -54.3 -36.3 -7.3 -20.1 -6.9 58 63 A I H > S+ 0 0 107 2,-0.2 4,-2.2 1,-0.2 -1,-0.2 0.932 111.5 43.3 -71.2 -49.6 -4.5 -19.0 -9.2 59 64 A H H > S+ 0 0 39 2,-0.2 4,-2.5 1,-0.2 -2,-0.2 0.892 114.8 53.4 -59.4 -42.5 -6.6 -16.6 -11.3 60 65 A A H X S+ 0 0 0 -4,-3.0 4,-2.1 1,-0.2 -2,-0.2 0.927 110.7 43.0 -64.4 -45.9 -8.2 -15.3 -8.1 61 66 A K H X S+ 0 0 27 -4,-2.6 4,-2.7 2,-0.2 -1,-0.2 0.854 113.8 53.4 -67.4 -36.2 -4.9 -14.5 -6.4 62 67 A R H X S+ 0 0 99 -4,-2.2 4,-2.6 2,-0.2 -2,-0.2 0.910 107.8 50.7 -63.1 -42.4 -3.6 -13.0 -9.7 63 68 A T H X S+ 0 0 9 -4,-2.5 4,-2.4 -10,-0.4 -2,-0.2 0.943 112.9 46.0 -58.1 -47.6 -6.7 -10.7 -9.9 64 69 A Y H X S+ 0 0 14 -4,-2.1 4,-2.9 1,-0.2 -2,-0.2 0.919 112.6 50.4 -60.8 -50.1 -6.1 -9.6 -6.3 65 70 A R H X S+ 0 0 74 -4,-2.7 4,-2.4 2,-0.2 -1,-0.2 0.873 110.2 50.1 -52.5 -44.9 -2.3 -9.1 -6.9 66 71 A E H X S+ 0 0 15 -4,-2.6 4,-2.6 2,-0.2 5,-0.2 0.922 113.2 45.2 -66.5 -45.1 -3.1 -7.0 -10.0 67 72 A L H X S+ 0 0 4 -4,-2.4 4,-2.8 2,-0.2 -2,-0.2 0.931 112.7 50.7 -63.5 -47.7 -5.5 -4.8 -8.2 68 73 A R H X S+ 0 0 33 -4,-2.9 4,-1.3 2,-0.2 -2,-0.2 0.922 113.6 46.1 -53.1 -47.8 -3.2 -4.4 -5.1 69 74 A L H X S+ 0 0 43 -4,-2.4 4,-1.5 2,-0.2 3,-0.3 0.931 114.8 45.4 -63.0 -48.1 -0.3 -3.3 -7.4 70 75 A L H < S+ 0 0 7 -4,-2.6 11,-0.8 1,-0.3 -1,-0.2 0.891 111.3 53.4 -66.6 -39.3 -2.3 -0.9 -9.5 71 76 A K H < S+ 0 0 41 -4,-2.8 -1,-0.3 -5,-0.2 -2,-0.2 0.811 109.9 50.0 -62.2 -30.6 -3.9 0.6 -6.4 72 77 A H H < S+ 0 0 35 -4,-1.3 2,-0.4 -3,-0.3 -1,-0.2 0.842 85.6 95.8 -77.8 -33.5 -0.5 1.2 -5.0 73 78 A M < + 0 0 15 -4,-1.5 8,-0.4 -3,-0.1 2,-0.3 -0.454 35.9 158.4 -74.7 114.1 1.3 2.9 -7.9 74 79 A K + 0 0 167 -2,-0.4 2,-0.3 6,-0.1 5,-0.1 -0.701 33.5 109.9-133.6 81.6 1.2 6.7 -7.6 75 80 A H B > S-F 78 0C 14 3,-0.5 3,-1.6 -2,-0.3 56,-0.0 -0.990 70.2-121.0-156.9 144.0 4.0 8.1 -9.8 76 81 A E T 3 S+ 0 0 100 -2,-0.3 4,-0.1 1,-0.3 -1,-0.1 0.777 112.8 45.4 -63.6 -27.9 4.3 9.9 -13.0 77 82 A N T 3 S+ 0 0 6 82,-0.1 83,-2.6 2,-0.1 2,-0.4 0.096 104.9 71.7-106.4 22.1 6.3 7.2 -14.8 78 83 A V B < S-Fg 75 160C 6 -3,-1.6 -3,-0.5 81,-0.3 83,-0.2 -1.000 89.2-106.3-134.6 135.8 4.2 4.3 -13.6 79 84 A I - 0 0 20 81,-2.7 2,-0.3 -2,-0.4 -6,-0.1 -0.286 43.1-165.9 -56.2 137.5 0.7 3.3 -14.8 80 85 A G - 0 0 20 -4,-0.1 2,-0.6 -6,-0.1 22,-0.4 -0.835 23.2-101.4-127.7 169.7 -1.9 4.2 -12.1 81 86 A L + 0 0 13 -11,-0.8 20,-0.2 -8,-0.4 3,-0.1 -0.807 27.5 177.0 -97.3 116.3 -5.5 3.3 -11.5 82 87 A L S S- 0 0 23 18,-2.9 2,-0.3 -2,-0.6 19,-0.2 0.782 73.7 -15.7 -78.7 -31.2 -8.1 5.9 -12.4 83 88 A D E -E 100 0B 20 17,-1.5 17,-3.0 250,-0.1 -1,-0.3 -0.977 49.5-163.0-167.2 154.3 -11.0 3.7 -11.4 84 89 A V E +E 99 0B 6 -2,-0.3 2,-0.3 15,-0.2 15,-0.2 -0.957 26.8 162.8-143.5 137.7 -12.0 0.1 -10.6 85 90 A F E -E 98 0B 14 13,-1.9 13,-2.2 -2,-0.3 244,-0.0 -0.987 24.9-155.5-151.2 160.0 -15.6 -1.0 -10.7 86 91 A T - 0 0 14 -2,-0.3 11,-0.1 11,-0.2 -70,-0.1 -0.993 23.8-134.9-134.3 146.2 -17.9 -4.0 -10.8 87 92 A P S S+ 0 0 15 0, 0.0 2,-0.2 0, 0.0 -83,-0.1 0.611 77.9 107.4 -66.8 -9.6 -21.5 -4.2 -12.0 88 93 A A - 0 0 14 8,-0.3 -2,-0.2 1,-0.1 6,-0.1 -0.442 57.5-159.4 -80.7 142.4 -22.2 -6.3 -8.9 89 94 A R S S+ 0 0 173 -2,-0.2 2,-0.3 1,-0.1 -1,-0.1 0.658 74.9 20.0 -94.2 -14.9 -24.2 -4.9 -5.9 90 95 A S S > S- 0 0 37 1,-0.1 3,-0.9 0, 0.0 4,-0.4 -0.957 81.5-103.6-145.2 162.6 -22.9 -7.4 -3.3 91 96 A L G > S+ 0 0 53 -2,-0.3 3,-1.7 1,-0.2 -1,-0.1 0.911 115.4 63.8 -48.4 -45.3 -20.1 -9.9 -2.7 92 97 A E G 3 S+ 0 0 162 1,-0.3 -1,-0.2 -3,-0.1 -4,-0.0 0.751 110.6 34.7 -60.4 -28.2 -22.4 -12.8 -3.5 93 98 A E G < S+ 0 0 109 -3,-0.9 2,-0.6 2,-0.0 -1,-0.3 0.283 86.4 126.8-104.6 10.5 -22.9 -11.7 -7.2 94 99 A F < + 0 0 0 -3,-1.7 3,-0.1 -4,-0.4 231,-0.1 -0.562 16.9 128.7 -74.2 111.6 -19.3 -10.3 -7.6 95 100 A N + 0 0 89 -2,-0.6 2,-0.4 1,-0.2 -41,-0.3 0.380 54.7 61.5-140.3 -3.4 -17.8 -12.0 -10.7 96 101 A D - 0 0 52 -44,-0.1 2,-0.4 -43,-0.1 -8,-0.3 -0.982 52.3-170.5-136.2 140.2 -16.4 -9.2 -13.0 97 102 A V - 0 0 2 -2,-0.4 -47,-2.7 -47,-0.3 2,-0.4 -0.999 2.7-167.9-133.8 133.3 -13.7 -6.6 -12.4 98 103 A Y E -DE 49 85B 1 -13,-2.2 -13,-1.9 -2,-0.4 2,-0.4 -0.966 6.3-157.7-122.9 138.6 -13.0 -3.6 -14.7 99 104 A L E -DE 48 84B 5 -51,-2.4 -51,-3.4 -2,-0.4 2,-0.5 -0.942 3.7-157.2-119.7 135.6 -9.8 -1.5 -14.4 100 105 A V E +DE 47 83B 0 -17,-3.0 -18,-2.9 -2,-0.4 -17,-1.5 -0.958 20.7 158.6-119.9 126.8 -9.5 2.1 -15.7 101 106 A T E -D 46 0B 19 -55,-2.3 -55,-3.1 -2,-0.5 -20,-0.1 -0.873 49.3 -75.0-135.2 165.8 -6.2 3.7 -16.5 102 107 A H E -D 45 0B 76 -22,-0.4 2,-0.6 -2,-0.3 -57,-0.2 -0.349 49.4-118.4 -56.5 140.5 -5.0 6.7 -18.7 103 108 A L - 0 0 61 -59,-1.6 2,-0.3 -67,-0.1 -59,-0.1 -0.787 32.9-155.5 -83.1 119.6 -5.0 5.8 -22.4 104 109 A M - 0 0 33 -2,-0.6 49,-0.1 1,-0.1 3,-0.1 -0.706 17.7-120.7 -98.2 154.9 -1.4 6.1 -23.6 105 110 A G S S- 0 0 64 -2,-0.3 2,-0.2 47,-0.1 48,-0.2 0.937 72.5 -39.3 -56.9 -60.4 -0.5 6.8 -27.2 106 111 A A E -H 152 0C 38 46,-1.7 46,-2.4 5,-0.0 2,-0.2 -0.838 61.5 -93.0-156.6-178.1 1.7 3.8 -28.2 107 112 A D E > -H 151 0C 32 44,-0.2 4,-1.2 -2,-0.2 44,-0.2 -0.705 36.9-107.4-112.5 167.2 4.3 1.5 -26.8 108 113 A L T 4 S+ 0 0 0 42,-1.9 40,-0.2 39,-1.4 43,-0.1 0.774 122.2 55.1 -67.9 -25.7 8.1 1.8 -27.0 109 114 A N T >4 S+ 0 0 60 38,-0.5 3,-0.5 41,-0.2 -1,-0.2 0.950 103.3 55.8 -65.9 -48.3 8.2 -1.1 -29.5 110 115 A N T 34 S+ 0 0 116 1,-0.3 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A I - 0 0 18 -10,-2.1 2,-0.1 -2,-0.2 -1,-0.1 -0.290 34.0-127.1 -66.4 149.9 24.2 -0.2 -10.9 281 298 A T > - 0 0 57 1,-0.1 4,-2.3 -92,-0.1 5,-0.1 -0.452 23.2-107.9 -90.5 170.3 20.8 0.4 -9.1 282 299 A A H > S+ 0 0 3 2,-0.2 4,-2.0 1,-0.2 -149,-0.2 0.936 120.6 51.5 -64.2 -45.0 18.1 2.6 -10.5 283 300 A A H > S+ 0 0 49 1,-0.2 4,-0.8 2,-0.2 -1,-0.2 0.908 113.5 44.8 -57.4 -43.9 18.8 5.3 -7.8 284 301 A Q H >4 S+ 0 0 113 1,-0.2 3,-0.5 2,-0.2 4,-0.4 0.863 109.0 56.0 -69.8 -36.7 22.5 5.3 -8.8 285 302 A A H >< S+ 0 0 0 -4,-2.3 3,-1.6 1,-0.2 6,-0.2 0.888 100.3 60.3 -62.0 -37.3 21.8 5.3 -12.5 286 303 A L H 3< S+ 0 0 0 -4,-2.0 -1,-0.2 1,-0.3 -2,-0.2 0.810 103.7 50.1 -59.4 -35.1 19.7 8.4 -12.1 287 304 A A T << S+ 0 0 62 -4,-0.8 -1,-0.3 -3,-0.5 -2,-0.2 0.489 85.7 120.1 -84.2 -3.8 22.7 10.3 -10.8 288 305 A H S X S- 0 0 21 -3,-1.6 3,-1.9 -4,-0.4 7,-0.2 -0.257 76.6-116.0 -59.9 147.5 24.9 9.2 -13.7 289 306 A A G > S+ 0 0 56 1,-0.3 3,-2.0 2,-0.2 4,-0.2 0.780 108.7 72.6 -59.7 -29.7 26.4 11.9 -15.9 290 307 A Y G 3 S+ 0 0 3 -27,-0.3 3,-0.3 1,-0.3 -1,-0.3 0.778 98.3 48.7 -55.4 -26.3 24.4 10.8 -18.9 291 308 A F G X> S+ 0 0 0 -3,-1.9 4,-3.2 -6,-0.2 3,-2.2 0.129 73.9 126.5-103.0 19.8 21.2 12.2 -17.3 292 309 A A T <4 S+ 0 0 81 -3,-2.0 -1,-0.2 1,-0.3 -2,-0.1 0.806 71.1 49.4 -45.9 -41.8 22.8 15.6 -16.4 293 310 A Q T 34 S+ 0 0 119 -3,-0.3 -1,-0.3 -4,-0.2 -2,-0.1 0.565 124.1 28.6 -84.2 -4.1 20.1 17.7 -18.1 294 311 A Y T <4 S+ 0 0 74 -3,-2.2 -2,-0.2 -8,-0.1 -1,-0.2 0.646 87.0 110.7-120.1 -31.7 17.2 15.8 -16.4 295 312 A H < + 0 0 59 -4,-3.2 -8,-0.1 -7,-0.2 5,-0.1 -0.301 33.1 169.3 -59.6 132.4 18.4 14.5 -13.1 296 313 A D > - 0 0 68 3,-0.1 3,-2.3 1,-0.0 -1,-0.0 -0.849 22.8-159.1-142.8 105.5 16.8 16.3 -10.1 297 314 A P T 3 S+ 0 0 86 0, 0.0 3,-0.4 0, 0.0 -2,-0.0 0.637 94.4 53.6 -62.2 -12.8 17.5 14.6 -6.7 298 315 A D T 3 S+ 0 0 153 1,-0.2 -3,-0.0 3,-0.0 0, 0.0 0.458 107.0 49.7-102.0 -2.8 14.5 16.4 -5.2 299 316 A D S < S+ 0 0 77 -3,-2.3 -1,-0.2 1,-0.1 -3,-0.1 -0.214 85.1 88.3-127.2 44.8 12.0 15.2 -7.9 300 317 A E - 0 0 10 -3,-0.4 -1,-0.1 -5,-0.1 -14,-0.0 -0.635 67.0-169.6-136.9 70.5 12.7 11.4 -7.9 301 318 A P - 0 0 57 0, 0.0 2,-0.2 0, 0.0 -2,-0.1 -0.131 13.9-133.3 -72.1 159.1 10.4 10.2 -5.1 302 319 A V - 0 0 91 -165,-0.1 2,-0.2 -166,-0.1 -168,-0.2 -0.634 28.5-101.2-104.4 166.8 10.2 6.8 -3.5 303 320 A A - 0 0 13 -169,-0.6 3,-0.1 -170,-0.3 -230,-0.1 -0.584 28.7-104.3 -89.7 151.9 7.1 4.7 -2.9 304 321 A D - 0 0 120 -2,-0.2 -1,-0.1 -232,-0.2 -232,-0.0 -0.308 60.7 -81.4 -56.6 149.6 5.0 4.2 0.3 305 322 A P - 0 0 121 0, 0.0 2,-0.5 0, 0.0 -1,-0.1 -0.308 45.7-144.4 -59.9 146.2 5.7 0.7 1.7 306 323 A Y - 0 0 20 -168,-0.4 2,-1.1 -3,-0.1 -237,-0.0 -0.970 8.4-132.5-119.3 122.7 3.7 -2.1 -0.0 307 324 A D + 0 0 90 -2,-0.5 3,-0.4 1,-0.2 -169,-0.0 -0.619 32.4 166.5 -76.0 101.5 2.4 -5.1 1.9 308 325 A Q > + 0 0 58 -2,-1.1 3,-1.7 1,-0.2 4,-0.4 0.220 42.3 110.6 -96.4 12.0 3.4 -8.1 -0.1 309 326 A S G > + 0 0 39 1,-0.3 3,-1.7 2,-0.2 4,-0.3 0.835 64.8 69.1 -65.5 -28.0 2.6 -10.6 2.7 310 327 A F G > S+ 0 0 5 -3,-0.4 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