==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=14-MAR-2012 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER METAL BINDING PROTEIN 09-FEB-12 4DO0 . COMPND 2 MOLECULE: HISTONE LYSINE DEMETHYLASE PHF8; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR T.KROJER,M.DANIEL,S.S.NG,L.J.WALPORT,R.CHOWDHURY,C.H.ARROWSM . 363 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 16752.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 252 69.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 61 16.8 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 6.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 40 11.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 108 29.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 4 1.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 1 1 1 1 1 0 1 0 2 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 1 1 3 2 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 80 A V 0 0 109 0, 0.0 2,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 106.5 -10.5 -12.9 4.9 2 81 A K > - 0 0 61 1,-0.1 3,-1.4 210,-0.0 2,-0.4 -0.691 360.0-101.2 -99.0 138.6 -12.7 -15.5 6.8 3 82 A T T 3 S+ 0 0 12 207,-3.2 82,-0.3 -2,-0.3 -1,-0.1 -0.359 108.6 30.1 -58.7 106.9 -13.1 -15.8 10.6 4 83 A G T 3 S+ 0 0 3 -2,-0.4 -1,-0.2 1,-0.3 5,-0.2 -0.269 84.5 125.2 141.2 -47.7 -10.8 -18.7 11.6 5 84 A S S <> S- 0 0 25 -3,-1.4 4,-3.4 1,-0.1 -1,-0.3 0.169 71.0-114.6 -45.9 154.3 -8.0 -18.7 9.0 6 85 A P H > S+ 0 0 92 0, 0.0 4,-1.2 0, 0.0 -1,-0.1 0.642 122.5 51.0 -63.4 -17.2 -4.2 -18.5 9.9 7 86 A T H > S+ 0 0 85 2,-0.2 4,-2.2 3,-0.2 5,-0.2 0.826 110.6 48.1 -88.0 -39.7 -4.2 -15.2 8.2 8 87 A F H > S+ 0 0 17 -6,-0.3 4,-3.0 2,-0.2 5,-0.2 0.965 116.6 42.3 -59.4 -55.2 -7.2 -14.0 10.3 9 88 A V H X S+ 0 0 3 -4,-3.4 4,-3.2 1,-0.2 5,-0.2 0.952 112.0 55.9 -55.8 -49.0 -5.5 -15.3 13.5 10 89 A R H X S+ 0 0 54 -4,-1.2 4,-0.7 -5,-0.3 -1,-0.2 0.867 111.6 43.0 -53.7 -40.3 -2.2 -13.8 12.3 11 90 A E H >X S+ 0 0 117 -4,-2.2 3,-1.6 2,-0.2 4,-1.2 0.967 112.0 53.0 -70.9 -50.4 -3.9 -10.4 11.9 12 91 A L H >< S+ 0 0 10 -4,-3.0 3,-1.4 1,-0.3 -2,-0.2 0.908 101.9 60.0 -46.7 -48.2 -5.7 -10.7 15.2 13 92 A R H 3< S+ 0 0 89 -4,-3.2 -1,-0.3 1,-0.3 -2,-0.2 0.802 110.6 42.6 -55.0 -29.4 -2.4 -11.5 17.0 14 93 A S H << S+ 0 0 97 -3,-1.6 -1,-0.3 -4,-0.7 -2,-0.2 0.712 87.0 130.4 -85.4 -21.1 -1.2 -8.1 15.8 15 94 A R << - 0 0 29 -3,-1.4 -3,-0.1 -4,-1.2 -4,-0.0 -0.001 53.0-140.2 -59.8 136.6 -4.4 -6.2 16.6 16 95 A T + 0 0 142 207,-0.0 207,-0.1 0, 0.0 -1,-0.1 0.962 37.1 166.1 -49.4 -81.8 -4.2 -2.9 18.6 17 96 A F - 0 0 36 205,-0.1 2,-0.3 2,-0.1 205,-0.2 0.447 42.9 -75.7 72.6 153.8 -7.2 -2.9 21.0 18 97 A D E -a 222 0A 45 203,-1.8 205,-1.9 1,-0.1 2,-0.0 -0.648 58.1-103.4 -79.1 137.1 -8.4 -0.9 24.1 19 98 A S E > -a 223 0A 56 -2,-0.3 3,-1.0 203,-0.2 4,-0.4 -0.317 14.3-139.8 -67.0 142.5 -6.6 -1.9 27.3 20 99 A S T 3> S+ 0 0 19 203,-0.9 4,-1.9 1,-0.2 3,-0.5 0.659 94.9 78.5 -70.9 -21.3 -8.4 -4.2 29.8 21 100 A D T 34 S+ 0 0 107 1,-0.2 -1,-0.2 2,-0.2 5,-0.1 0.741 83.8 66.8 -64.4 -23.3 -6.9 -2.1 32.7 22 101 A E T <4 S+ 0 0 115 -3,-1.0 -1,-0.2 1,-0.1 -2,-0.2 0.923 117.8 13.4 -57.4 -51.5 -9.6 0.5 31.9 23 102 A V T 4 S+ 0 0 18 -3,-0.5 -2,-0.2 -4,-0.4 -1,-0.1 0.626 101.9 93.2-107.3 -17.8 -12.7 -1.6 32.9 24 103 A I < - 0 0 15 -4,-1.9 2,-0.4 20,-0.1 22,-0.2 -0.393 60.9-136.9 -85.7 159.4 -11.6 -4.7 34.8 25 104 A L B -e 46 0B 55 20,-2.0 22,-2.4 -2,-0.1 -2,-0.1 -0.886 9.1-162.5-108.0 147.6 -11.4 -5.1 38.5 26 105 A K + 0 0 115 -2,-0.4 23,-0.1 20,-0.2 22,-0.1 -0.414 25.7 158.1-127.4 56.2 -8.4 -6.9 40.0 27 106 A P - 0 0 8 0, 0.0 22,-0.4 0, 0.0 2,-0.2 -0.104 40.3-110.8 -62.7 177.1 -9.3 -7.9 43.6 28 107 A T >> - 0 0 79 20,-0.1 4,-1.1 21,-0.1 3,-0.8 -0.649 34.4 -98.1-106.3 166.0 -7.6 -10.7 45.4 29 108 A G G >4 S+ 0 0 3 23,-0.7 3,-0.9 21,-0.4 24,-0.2 0.885 123.6 47.5 -53.5 -44.0 -9.2 -13.9 46.4 30 109 A N G 34 S+ 0 0 118 22,-0.3 -1,-0.3 1,-0.3 23,-0.1 0.755 109.6 54.0 -74.3 -23.9 -10.0 -12.8 49.9 31 110 A Q G <4 S+ 0 0 110 -3,-0.8 2,-1.4 1,-0.1 -1,-0.3 0.620 88.0 86.9 -77.8 -19.0 -11.4 -9.5 48.7 32 111 A L << + 0 0 10 -4,-1.1 2,-0.2 -3,-0.9 -1,-0.1 -0.650 62.4 139.5 -91.3 85.0 -13.8 -11.2 46.2 33 112 A T S > S- 0 0 62 -2,-1.4 4,-1.9 1,-0.1 5,-0.2 -0.635 70.6 -98.5-119.1 171.8 -16.8 -11.9 48.5 34 113 A V H > S+ 0 0 45 -2,-0.2 4,-2.2 1,-0.2 5,-0.1 0.885 125.1 51.4 -58.3 -39.7 -20.5 -11.7 48.1 35 114 A E H > S+ 0 0 43 1,-0.2 4,-2.9 2,-0.2 5,-0.3 0.944 105.5 55.9 -63.2 -44.8 -20.4 -8.2 49.9 36 115 A F H > S+ 0 0 38 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.898 112.8 40.6 -56.6 -42.4 -17.7 -7.0 47.5 37 116 A L H X S+ 0 0 4 -4,-1.9 4,-1.1 2,-0.2 -1,-0.2 0.790 113.2 53.5 -80.3 -29.3 -20.0 -7.8 44.4 38 117 A E H < S+ 0 0 84 -4,-2.2 -2,-0.2 -5,-0.2 -1,-0.2 0.947 117.7 37.7 -62.7 -48.3 -23.2 -6.5 46.1 39 118 A E H < S+ 0 0 167 -4,-2.9 -2,-0.2 1,-0.2 -3,-0.2 0.952 128.3 33.0 -68.5 -53.6 -21.4 -3.2 46.8 40 119 A N H < S- 0 0 82 -4,-2.7 3,-0.3 -5,-0.3 -1,-0.2 0.653 104.9-137.3 -76.0 -15.2 -19.4 -2.9 43.6 41 120 A S < - 0 0 49 -4,-1.1 2,-0.2 -5,-0.2 3,-0.2 -0.052 19.5-100.7 66.9 173.4 -22.1 -4.7 41.5 42 121 A F S S+ 0 0 3 1,-0.1 194,-0.3 217,-0.1 -1,-0.2 -0.574 80.1 119.4-128.4 66.9 -20.9 -7.3 39.0 43 122 A S + 0 0 57 -3,-0.3 -1,-0.1 -2,-0.2 -2,-0.1 0.334 65.2 51.7-118.0 3.2 -21.0 -5.4 35.8 44 123 A V S S- 0 0 24 -3,-0.2 -20,-0.1 147,-0.1 -19,-0.1 -0.971 94.1 -90.7-136.3 152.7 -17.4 -5.5 34.7 45 124 A P - 0 0 0 0, 0.0 -20,-2.0 0, 0.0 2,-0.4 -0.244 36.4-147.6 -63.5 152.6 -15.0 -8.4 34.3 46 125 A I E -eF 25 233B 1 187,-1.9 187,-2.1 -22,-0.2 2,-0.7 -0.979 10.1-168.1-131.3 116.6 -12.9 -9.4 37.2 47 126 A L E - F 0 232B 11 -22,-2.4 2,-0.6 -2,-0.4 185,-0.2 -0.893 3.3-164.9-109.4 106.1 -9.4 -10.9 36.9 48 127 A V E - F 0 231B 1 183,-2.5 183,-2.3 -2,-0.7 -20,-0.1 -0.825 8.0-155.1 -87.7 127.7 -7.8 -12.4 40.0 49 128 A L S S+ 0 0 89 -2,-0.6 2,-0.4 -22,-0.4 -1,-0.1 0.905 75.8 28.3 -70.0 -42.6 -4.1 -12.9 39.6 50 129 A K S S- 0 0 116 2,-0.2 -21,-0.4 180,-0.1 -1,-0.1 -0.955 73.4-131.5-126.5 145.3 -3.5 -15.7 42.2 51 130 A K > > + 0 0 87 -2,-0.4 3,-2.1 178,-0.3 5,-0.5 0.523 67.0 119.3 -75.2 -8.9 -6.0 -18.4 43.2 52 131 A D T 3 5S+ 0 0 123 1,-0.3 -23,-0.7 2,-0.1 -22,-0.3 -0.418 81.1 21.3 -61.4 130.2 -5.4 -17.9 47.0 53 132 A G T 3 5S+ 0 0 32 -24,-0.2 -1,-0.3 -23,-0.1 -2,-0.1 0.102 96.5 96.8 96.8 -19.6 -8.7 -16.9 48.6 54 133 A L T < 5S- 0 0 5 -3,-2.1 75,-3.0 -4,-0.1 76,-0.4 0.583 86.7-129.2 -75.4 -11.5 -11.0 -18.2 45.7 55 134 A G T 5 + 0 0 41 -4,-0.4 2,-0.3 1,-0.2 -3,-0.1 0.741 55.0 152.2 67.3 20.3 -11.7 -21.5 47.6 56 135 A M < - 0 0 7 -5,-0.5 2,-0.4 72,-0.1 -1,-0.2 -0.653 35.4-158.5 -84.7 144.7 -10.7 -23.5 44.5 57 136 A T B +M 126 0C 83 69,-1.2 69,-2.7 -2,-0.3 67,-0.0 -0.971 28.5 157.5-111.3 131.4 -9.3 -27.0 44.5 58 137 A L - 0 0 29 -2,-0.4 67,-0.2 67,-0.2 69,-0.0 -0.989 42.3-103.4-147.8 154.5 -7.4 -27.9 41.3 59 138 A P - 0 0 25 0, 0.0 65,-0.0 0, 0.0 -1,-0.0 -0.141 58.2 -76.7 -68.6-178.5 -4.8 -30.3 40.1 60 139 A S > - 0 0 57 1,-0.1 3,-2.3 2,-0.0 121,-0.0 -0.356 41.5-101.3 -81.2 161.7 -1.3 -29.0 39.6 61 140 A P T 3 S+ 0 0 70 0, 0.0 -1,-0.1 0, 0.0 167,-0.0 0.402 119.5 66.2 -57.8 2.9 -0.0 -26.8 36.7 62 141 A S T 3 + 0 0 85 2,-0.1 120,-0.0 120,-0.0 119,-0.0 0.359 68.7 121.4-111.3 -0.8 1.5 -30.1 35.4 63 142 A F < - 0 0 15 -3,-2.3 2,-0.3 1,-0.1 186,-0.1 -0.222 49.7-157.6 -48.4 152.5 -1.8 -31.9 34.7 64 143 A T > - 0 0 38 1,-0.1 4,-2.1 0, 0.0 5,-0.1 -0.877 35.2-100.2-139.1 167.9 -2.1 -32.8 31.0 65 144 A V H > S+ 0 0 8 -2,-0.3 4,-2.1 1,-0.2 3,-0.2 0.936 124.2 54.7 -55.2 -45.8 -4.4 -33.7 28.2 66 145 A R H > S+ 0 0 129 1,-0.2 4,-2.9 2,-0.2 -1,-0.2 0.876 103.0 54.8 -56.7 -42.5 -3.5 -37.3 28.9 67 146 A D H > S+ 0 0 50 2,-0.2 4,-2.7 1,-0.2 -1,-0.2 0.924 106.0 53.6 -56.4 -38.5 -4.6 -36.9 32.6 68 147 A V H X S+ 0 0 0 -4,-2.1 4,-3.0 2,-0.2 5,-0.4 0.949 108.6 48.1 -59.9 -49.0 -7.9 -35.7 31.3 69 148 A E H X S+ 0 0 25 -4,-2.1 4,-2.0 1,-0.2 -1,-0.2 0.934 109.6 54.6 -57.1 -46.0 -8.3 -38.8 29.2 70 149 A H H < S+ 0 0 110 -4,-2.9 -2,-0.2 1,-0.2 -1,-0.2 0.961 116.3 35.2 -51.3 -54.4 -7.4 -40.9 32.2 71 150 A Y H < S+ 0 0 58 -4,-2.7 49,-1.1 1,-0.2 50,-0.5 0.794 125.4 36.8 -80.2 -26.1 -10.1 -39.3 34.4 72 151 A V H < S- 0 0 19 -4,-3.0 -3,-0.2 -5,-0.2 -1,-0.2 0.859 110.6-106.2 -90.3 -40.3 -12.9 -38.8 31.8 73 152 A G >< - 0 0 28 -4,-2.0 3,-1.9 -5,-0.4 20,-0.3 0.301 10.5-113.4 111.4 118.7 -12.6 -41.9 29.6 74 153 A S T 3 S+ 0 0 54 1,-0.2 20,-2.5 -5,-0.2 21,-0.3 0.739 113.5 54.1 -37.2 -39.3 -11.3 -42.4 26.1 75 154 A D T 3 S+ 0 0 135 18,-0.2 -1,-0.2 17,-0.2 -2,-0.1 0.525 76.9 116.6 -85.8 -6.9 -14.8 -43.4 24.8 76 155 A K < - 0 0 53 -3,-1.9 17,-2.2 16,-0.1 2,-0.3 -0.363 68.1-120.8 -66.2 137.6 -16.7 -40.3 26.0 77 156 A E E -G 92 0B 112 15,-0.2 2,-0.4 16,-0.1 15,-0.2 -0.652 33.9-171.7 -76.2 135.5 -18.2 -38.2 23.2 78 157 A I E -G 91 0B 4 13,-2.6 13,-0.7 -2,-0.3 2,-0.3 -0.993 25.1-121.6-133.6 139.7 -17.0 -34.6 23.1 79 158 A D E -G 90 0B 49 -2,-0.4 34,-0.4 11,-0.2 33,-0.3 -0.574 35.4-176.6 -77.2 133.5 -18.1 -31.6 21.1 80 159 A V E -G 89 0B 0 9,-3.0 9,-1.9 -2,-0.3 2,-0.4 -0.882 15.2-143.0-124.0 158.0 -15.2 -30.2 19.1 81 160 A I E -GH 88 110B 24 29,-1.5 29,-1.2 -2,-0.3 2,-0.7 -0.995 10.6-136.8-126.4 136.6 -15.1 -27.1 16.9 82 161 A D E >> -GH 87 109B 25 5,-2.7 5,-1.1 -2,-0.4 4,-0.6 -0.806 17.1-162.3 -88.3 114.0 -13.1 -26.8 13.6 83 162 A V T 45S+ 0 0 0 25,-2.9 2,-0.5 -2,-0.7 -1,-0.1 0.708 85.8 53.7 -79.2 -21.5 -11.6 -23.4 13.9 84 163 A T T 45S+ 0 0 60 24,-0.3 -1,-0.3 1,-0.2 -80,-0.1 -0.510 124.6 29.6-102.4 58.9 -10.7 -23.0 10.2 85 164 A R T 45S- 0 0 61 -2,-0.5 -2,-0.2 -3,-0.5 -1,-0.2 0.197 95.5-133.7 169.4 -14.9 -14.4 -23.7 9.5 86 165 A Q T <5 + 0 0 69 -4,-0.6 2,-0.3 1,-0.1 -3,-0.2 0.783 60.7 138.3 36.1 43.2 -16.2 -22.5 12.6 87 166 A A E < -G 82 0B 50 -5,-1.1 -5,-2.7 2,-0.0 2,-0.3 -0.902 47.5-130.7-122.9 147.1 -18.2 -25.8 12.6 88 167 A D E +G 81 0B 126 -2,-0.3 2,-0.3 -7,-0.2 -7,-0.2 -0.683 30.3 155.3 -98.9 140.9 -19.4 -28.3 15.4 89 168 A C E -G 80 0B 58 -9,-1.9 -9,-3.0 -2,-0.3 2,-0.2 -0.989 39.0-110.4-154.5 157.2 -19.0 -32.1 15.6 90 169 A K E +G 79 0B 130 -2,-0.3 2,-0.3 -11,-0.2 -11,-0.2 -0.494 37.8 172.1 -78.8 157.2 -18.8 -35.0 18.0 91 170 A M E -G 78 0B 36 -13,-0.7 -13,-2.6 -2,-0.2 2,-0.4 -0.955 37.7-102.3-163.7 151.1 -15.5 -36.9 18.4 92 171 A K E >> -G 77 0B 52 -2,-0.3 4,-2.3 -15,-0.2 3,-0.7 -0.706 29.5-127.3 -84.4 132.7 -14.2 -39.6 20.8 93 172 A L H 3> S+ 0 0 0 -17,-2.2 4,-2.9 -2,-0.4 -18,-0.2 0.873 110.0 58.8 -41.3 -46.9 -12.0 -38.1 23.5 94 173 A G H 3> S+ 0 0 14 -20,-2.5 4,-3.3 1,-0.3 -1,-0.2 0.901 105.6 46.5 -50.3 -48.3 -9.3 -40.7 22.4 95 174 A D H <> S+ 0 0 83 -3,-0.7 4,-3.0 -21,-0.3 -1,-0.3 0.894 110.0 54.8 -67.7 -35.0 -9.2 -39.4 18.9 96 175 A F H X S+ 0 0 0 -4,-2.3 4,-4.2 2,-0.2 -2,-0.2 0.966 110.6 45.5 -57.9 -50.3 -9.0 -35.9 20.3 97 176 A V H X S+ 0 0 12 -4,-2.9 4,-2.9 2,-0.2 5,-0.4 0.917 110.5 53.0 -61.0 -45.3 -6.0 -37.0 22.3 98 177 A K H X S+ 0 0 106 -4,-3.3 4,-2.1 1,-0.2 -1,-0.2 0.981 115.3 42.3 -46.4 -59.9 -4.4 -38.8 19.3 99 178 A Y H X S+ 0 0 28 -4,-3.0 4,-1.3 1,-0.2 5,-0.5 0.935 113.8 53.6 -55.1 -51.0 -4.9 -35.5 17.4 100 179 A Y H < S+ 0 0 39 -4,-4.2 3,-0.4 -5,-0.2 -2,-0.2 0.963 114.2 35.9 -50.1 -66.2 -3.7 -33.5 20.3 101 180 A Y H < S+ 0 0 114 -4,-2.9 -1,-0.2 1,-0.2 -2,-0.2 0.709 105.7 73.1 -73.1 -16.0 -0.3 -35.1 21.0 102 181 A S H < S- 0 0 75 -4,-2.1 -1,-0.2 -5,-0.4 -2,-0.2 0.983 90.7-139.8 -49.0 -62.6 0.4 -35.8 17.3 103 182 A G < + 0 0 47 -4,-1.3 2,-2.0 -3,-0.4 -3,-0.1 0.376 50.4 145.5 105.5 3.2 1.1 -32.1 16.4 104 183 A K > + 0 0 59 -5,-0.5 2,-1.7 1,-0.1 3,-0.9 -0.486 21.0 176.9 -78.6 78.6 -0.8 -32.4 13.1 105 184 A R T 3 + 0 0 90 -2,-2.0 -1,-0.1 1,-0.2 3,-0.1 -0.187 45.2 113.0 -76.5 46.5 -2.1 -28.8 13.0 106 185 A E T 3 S+ 0 0 95 -2,-1.7 2,-0.4 1,-0.2 -1,-0.2 0.835 87.5 32.4 -85.2 -38.7 -3.7 -29.3 9.6 107 186 A K S < S- 0 0 124 -3,-0.9 2,-0.7 -24,-0.0 -1,-0.2 -0.881 83.6-144.1-103.8 147.1 -7.0 -29.0 11.3 108 187 A V - 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