==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE/HYDROLASE INHIBITOR 23-DEC-99 1DP5 . COMPND 2 MOLECULE: PROTEINASE A; . SOURCE 2 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; . AUTHOR M.LI,H.L.PHYLIP,W.E.LEES,J.R.WINTHER,B.M.DUNN,A.WLODAWER,J.K . 360 2 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 14347.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 267 74.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 20 5.6 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 108 30.0 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 5 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 39 10.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 10.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 49 13.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 8 2.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 3 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 RESIDUES PER ALPHA HELIX . 1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 5 2 4 4 2 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 2 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 0 A G 0 0 85 0, 0.0 174,-0.1 0, 0.0 2,-0.1 0.000 360.0 360.0 360.0-134.6 17.2 127.3 2.9 2 1 A G - 0 0 25 145,-0.0 2,-0.7 172,-0.0 170,-0.2 0.023 360.0 -24.3-122.2-128.9 14.8 129.0 5.2 3 2 A H E -A 171 0A 44 168,-3.0 168,-2.4 -2,-0.1 2,-0.3 -0.825 62.5-145.8 -99.2 113.7 12.0 131.5 4.4 4 3 A D E -A 170 0A 73 -2,-0.7 90,-0.3 166,-0.2 166,-0.2 -0.556 11.1-165.5 -79.2 137.5 12.6 133.3 1.1 5 4 A V E -A 169 0A 1 164,-3.0 164,-2.6 -2,-0.3 -2,-0.0 -0.983 20.3-126.0-128.2 117.1 11.4 136.9 0.8 6 5 A P E -A 168 0A 92 0, 0.0 2,-0.4 0, 0.0 12,-0.3 -0.263 21.2-149.1 -59.6 143.3 11.2 138.5 -2.6 7 6 A L - 0 0 8 160,-1.6 159,-0.6 10,-0.1 2,-0.6 -0.970 3.6-143.9-119.7 134.6 13.0 141.8 -3.2 8 7 A T E -F 16 0B 62 8,-3.1 8,-2.2 -2,-0.4 2,-0.5 -0.857 16.4-152.1 -97.9 125.4 11.9 144.6 -5.5 9 8 A N E -F 15 0B 27 -2,-0.6 2,-0.7 6,-0.2 6,-0.2 -0.865 7.5-165.7-101.4 124.7 14.8 146.4 -7.2 10 9 A Y E >> S-F 14 0B 46 4,-2.8 3,-2.3 -2,-0.5 4,-1.2 -0.907 72.6 -40.3-112.3 103.8 14.4 149.9 -8.3 11 10 A L T 34 S- 0 0 29 -2,-0.7 -1,-0.1 1,-0.3 4,-0.1 0.645 98.3 -77.4 58.4 19.0 17.1 151.1 -10.6 12 11 A N T 34 S+ 0 0 8 2,-0.3 -1,-0.3 1,-0.1 3,-0.1 0.624 123.7 94.8 66.7 10.6 19.8 149.2 -8.7 13 12 A A T <4 S+ 0 0 1 -3,-2.3 209,-0.5 1,-0.3 2,-0.3 0.675 88.0 16.1-103.8 -24.5 19.5 152.1 -6.3 14 13 A Q E < -F 10 0B 16 -4,-1.2 -4,-2.8 207,-0.1 2,-0.4 -0.984 58.1-160.9-154.1 139.0 17.1 150.8 -3.7 15 14 A Y E +F 9 0B 11 -2,-0.3 17,-0.4 204,-0.2 2,-0.3 -0.979 19.8 166.8-122.5 131.0 15.7 147.4 -2.7 16 15 A Y E -F 8 0B 20 -8,-2.2 -8,-3.1 -2,-0.4 2,-0.3 -0.919 16.0-155.6-139.8 169.8 12.5 146.9 -0.7 17 16 A T E -G 30 0C 5 13,-2.7 13,-3.0 -2,-0.3 2,-0.3 -0.942 24.1-104.8-141.4 164.0 10.0 144.2 0.3 18 17 A D E +G 29 0C 95 -2,-0.3 75,-0.5 -12,-0.3 2,-0.3 -0.680 38.4 165.0 -90.2 139.8 6.4 143.9 1.4 19 18 A I E -G 28 0C 2 9,-2.2 9,-2.0 -2,-0.3 2,-0.3 -0.848 21.2-142.4-138.6 174.0 5.5 143.2 5.0 20 19 A T E -GH 27 91C 25 71,-1.6 71,-2.0 -2,-0.3 2,-0.3 -0.972 8.2-165.5-139.8 154.5 2.2 143.4 6.9 21 20 A L E > +GH 26 90C 0 5,-1.7 5,-2.6 -2,-0.3 69,-0.2 -0.969 50.0 11.9-134.8 148.0 1.3 144.5 10.4 22 21 A G T 5S- 0 0 6 67,-1.1 4,-0.1 -2,-0.3 40,-0.1 0.137 87.5 -49.0 79.9 170.0 -1.9 143.9 12.3 23 22 A T T 5S+ 0 0 61 2,-0.1 40,-2.6 1,-0.1 41,-0.2 -0.965 129.6 29.0-130.8 113.7 -5.1 141.9 11.9 24 23 A P T 5S- 0 0 93 0, 0.0 -3,-0.1 0, 0.0 -1,-0.1 0.533 122.1 -98.2 -67.9 161.4 -6.4 142.1 9.3 25 24 A P T 5 - 0 0 83 0, 0.0 2,-0.5 0, 0.0 -3,-0.2 -0.218 31.9-156.9 -57.1 131.7 -3.0 142.6 7.6 26 25 A Q E < -G 21 0C 33 -5,-2.6 -5,-1.7 -4,-0.1 2,-0.2 -0.943 21.5-130.0-108.6 126.4 -2.0 146.2 6.7 27 26 A N E +G 20 0C 106 -2,-0.5 2,-0.3 -7,-0.2 -7,-0.2 -0.550 29.4 170.7 -84.0 140.8 0.6 146.4 3.9 28 27 A F E -G 19 0C 3 -9,-2.0 -9,-2.2 -2,-0.2 2,-0.6 -0.996 29.2-136.8-145.7 146.6 3.9 148.3 3.9 29 28 A K E +G 18 0C 80 -2,-0.3 90,-3.0 -11,-0.2 91,-1.6 -0.919 36.7 174.9-101.0 125.3 6.9 148.5 1.6 30 29 A V E -Gi 17 120C 0 -13,-3.0 -13,-2.7 -2,-0.6 2,-0.5 -0.935 34.0-118.6-132.7 156.7 10.1 148.5 3.8 31 30 A I E - i 0 121C 5 89,-1.5 91,-2.5 -2,-0.3 2,-1.0 -0.826 24.2-135.1 -90.7 127.4 13.8 148.5 3.2 32 31 A L E - i 0 122C 5 -2,-0.5 2,-0.6 -17,-0.4 91,-0.2 -0.765 36.1-169.7 -80.8 108.9 15.5 145.4 4.8 33 32 A D E > - i 0 123C 0 89,-2.4 91,-2.8 -2,-1.0 3,-1.4 -0.861 32.7-178.8-115.4 103.5 18.4 147.3 6.3 34 33 A T T 3 S+ 0 0 1 -2,-0.6 160,-0.5 1,-0.2 92,-0.2 0.552 83.1 72.0 -73.5 -0.8 21.4 145.6 7.9 35 34 A G T 3 S+ 0 0 3 158,-0.1 2,-0.3 90,-0.1 -1,-0.2 0.435 104.7 29.1 -92.6 1.5 22.6 149.1 8.7 36 35 A S < - 0 0 18 -3,-1.4 89,-2.4 86,-0.1 88,-0.6 -0.955 64.6-141.5-151.1 169.4 20.1 149.7 11.5 37 36 A S + 0 0 1 92,-0.4 2,-0.3 -2,-0.3 93,-0.1 0.176 63.4 88.0-127.1 19.0 18.1 147.7 14.0 38 37 A N - 0 0 11 98,-0.1 85,-1.7 91,-0.1 2,-0.5 -0.892 57.2-142.3-119.1 150.9 14.6 149.2 14.4 39 38 A L E +J 122 0C 3 -2,-0.3 64,-2.3 83,-0.3 2,-0.3 -0.909 33.0 161.0-104.4 135.9 11.3 148.5 12.5 40 39 A W E +Jk 121 103C 6 81,-2.1 81,-1.5 -2,-0.5 64,-0.2 -0.980 14.3 178.7-152.8 148.2 9.2 151.6 12.0 41 40 A V E - k 0 104C 0 62,-1.8 64,-2.7 -2,-0.3 79,-0.2 -0.916 44.8 -77.1-141.0 164.4 6.3 152.5 9.7 42 41 A P E - k 0 105C 0 0, 0.0 15,-3.2 0, 0.0 2,-0.2 -0.417 45.3-129.9 -67.4 138.2 4.2 155.7 9.4 43 42 A S B > -n 57 0D 0 62,-2.9 3,-1.6 13,-0.2 15,-0.2 -0.612 10.6-130.4 -86.1 149.7 1.6 156.3 12.0 44 43 A N T 3 S+ 0 0 84 13,-2.0 -1,-0.1 1,-0.3 14,-0.1 0.783 111.5 59.3 -66.1 -25.4 -2.0 157.1 10.9 45 44 A E T 3 S+ 0 0 98 12,-0.3 2,-0.3 2,-0.0 -1,-0.3 0.347 80.9 118.7 -83.1 3.4 -1.7 159.9 13.5 46 45 A a < - 0 0 5 -3,-1.6 61,-0.2 59,-0.2 60,-0.1 -0.544 45.0-168.6 -78.9 133.9 1.3 161.4 11.8 47 46 A G + 0 0 62 59,-1.2 2,-0.3 -2,-0.3 -1,-0.1 0.174 48.1 113.1-106.5 17.9 0.9 165.0 10.4 48 47 A S S > S- 0 0 22 58,-0.1 4,-1.7 1,-0.1 3,-0.4 -0.633 74.2-121.6 -88.4 152.4 4.1 165.2 8.3 49 48 A L H > S+ 0 0 112 -2,-0.3 4,-1.7 1,-0.2 -1,-0.1 0.885 112.3 58.7 -54.7 -43.3 4.0 165.5 4.5 50 49 A A H 4 S+ 0 0 0 58,-0.5 -1,-0.2 1,-0.2 4,-0.1 0.890 103.9 52.5 -57.7 -39.0 6.1 162.3 4.2 51 50 A a H >4 S+ 0 0 0 -3,-0.4 3,-1.8 1,-0.2 -1,-0.2 0.911 104.9 53.3 -65.0 -41.8 3.4 160.4 6.1 52 51 A F H 3< S+ 0 0 136 -4,-1.7 -1,-0.2 1,-0.3 -2,-0.2 0.858 106.6 55.0 -60.4 -33.5 0.6 161.5 3.8 53 52 A L T 3< S+ 0 0 91 -4,-1.7 -1,-0.3 2,-0.1 2,-0.3 0.391 109.3 53.3 -82.6 5.3 2.6 160.3 0.9 54 53 A H S < S- 0 0 21 -3,-1.8 2,-0.2 -4,-0.1 65,-0.1 -0.856 94.3 -84.5-135.1 169.1 3.0 156.7 2.3 55 54 A S - 0 0 59 -2,-0.3 2,-0.3 -26,-0.1 -26,-0.1 -0.512 49.8-149.9 -70.0 143.1 0.9 153.8 3.6 56 55 A K - 0 0 53 -2,-0.2 2,-0.5 -15,-0.1 -13,-0.2 -0.885 11.7-118.6-121.9 150.5 0.2 154.3 7.3 57 56 A Y B -n 43 0D 0 -15,-3.2 -13,-2.0 -2,-0.3 2,-0.7 -0.728 21.7-166.0 -86.6 126.5 -0.4 152.0 10.2 58 57 A D > - 0 0 48 -2,-0.5 3,-1.4 -15,-0.2 4,-0.2 -0.851 5.4-174.6-113.3 95.9 -3.8 152.3 11.9 59 58 A H G > S+ 0 0 19 -2,-0.7 3,-1.0 1,-0.3 6,-0.3 0.733 80.7 64.4 -65.9 -18.4 -3.7 150.4 15.2 60 59 A E G 3 S+ 0 0 162 1,-0.2 -1,-0.3 3,-0.0 -2,-0.0 0.758 99.4 53.7 -73.8 -22.5 -7.4 151.0 15.9 61 60 A A G < S+ 0 0 53 -3,-1.4 2,-0.6 1,-0.0 -1,-0.2 0.409 96.2 86.4 -89.4 3.3 -8.2 148.8 12.9 62 61 A S X - 0 0 11 -3,-1.0 3,-0.9 -4,-0.2 -40,-0.1 -0.903 54.8-167.9-113.5 120.9 -6.0 146.0 14.2 63 62 A S T 3 S+ 0 0 103 -40,-2.6 -1,-0.1 -2,-0.6 -4,-0.0 0.687 91.8 53.6 -73.6 -18.9 -7.4 143.4 16.7 64 63 A S T 3 S+ 0 0 34 -41,-0.2 -1,-0.2 25,-0.1 35,-0.2 0.411 80.6 119.1 -95.6 2.2 -3.8 142.1 17.4 65 64 A Y < - 0 0 56 -3,-0.9 2,-0.4 -6,-0.3 23,-0.2 -0.445 42.5-169.3 -68.0 138.8 -2.4 145.6 18.4 66 65 A K E -L 87 0C 120 21,-2.8 21,-2.2 -2,-0.1 2,-0.1 -0.994 21.2-123.9-127.8 134.8 -1.1 145.9 21.9 67 66 A A E +L 86 0C 53 -2,-0.4 19,-0.2 19,-0.2 18,-0.0 -0.380 41.1 152.0 -79.0 157.6 -0.3 149.4 23.2 68 67 A N E - 0 0 76 17,-0.6 18,-0.2 -2,-0.1 -1,-0.1 0.296 23.0-165.4-145.2 -61.7 3.1 150.4 24.7 69 68 A G E + 0 0 44 16,-2.7 17,-0.1 1,-0.2 3,-0.1 0.364 25.6 156.0 84.8 -5.6 3.6 154.2 24.0 70 69 A T E - 0 0 71 15,-0.2 15,-2.2 14,-0.1 -1,-0.2 -0.335 50.5-104.8 -59.7 129.9 7.3 154.5 24.7 71 70 A E E -L 84 0C 167 13,-0.2 2,-0.4 -2,-0.1 13,-0.3 -0.303 37.2-167.2 -60.0 139.3 8.8 157.5 23.0 72 71 A F E +L 83 0C 4 11,-3.1 11,-2.4 32,-0.1 2,-0.3 -0.988 14.8 157.3-129.3 132.6 10.8 156.9 19.9 73 72 A A E -L 82 0C 44 -2,-0.4 2,-0.4 9,-0.2 9,-0.2 -0.971 19.5-175.4-159.0 142.9 13.1 159.4 18.1 74 73 A I E -L 81 0C 13 7,-2.5 7,-2.7 -2,-0.3 2,-0.5 -0.990 26.0-135.3-135.2 128.0 16.0 159.4 15.7 75 74 A Q E -L 80 0C 101 -2,-0.4 2,-0.3 5,-0.2 5,-0.2 -0.742 21.5-177.0 -89.9 124.5 17.6 162.8 14.8 76 75 A Y E > -L 79 0C 12 3,-2.0 3,-1.1 -2,-0.5 271,-0.1 -0.794 40.7-106.1-111.1 161.8 18.5 163.4 11.2 77 76 A G T 3 S+ 0 0 82 269,-0.3 3,-0.1 -2,-0.3 -1,-0.1 0.841 118.3 39.7 -57.1 -30.8 20.2 166.6 10.0 78 77 A T T 3 S- 0 0 75 1,-0.3 2,-0.3 31,-0.0 -1,-0.2 0.464 131.5 -35.2-101.3 -4.9 17.1 168.0 8.5 79 78 A G E < -L 76 0C 27 -3,-1.1 -3,-2.0 30,-0.1 2,-0.4 -0.907 68.5 -83.4 163.5 172.0 14.5 167.0 11.0 80 79 A S E -L 75 0C 26 -2,-0.3 2,-0.6 -5,-0.2 -5,-0.2 -0.850 17.4-137.4-115.4 146.5 13.6 164.2 13.4 81 80 A L E +L 74 0C 0 -7,-2.7 -7,-2.5 -2,-0.4 2,-0.3 -0.843 40.3 171.6 -89.1 119.4 11.9 160.9 13.0 82 81 A E E +LM 73 107C 84 25,-2.3 25,-1.9 -2,-0.6 24,-1.4 -0.946 13.1 110.7-134.3 155.0 9.6 160.6 16.1 83 82 A G E -LM 72 105C 8 -11,-2.4 -11,-3.1 -2,-0.3 2,-0.3 -0.939 50.1 -93.1 172.9-158.0 6.9 158.3 17.2 84 83 A Y E -LM 71 104C 41 20,-1.8 20,-2.6 -2,-0.3 -13,-0.2 -0.957 37.0 -89.4-146.6 163.2 6.2 155.7 19.9 85 84 A I E + M 0 103C 4 -15,-2.2 -16,-2.7 -2,-0.3 -17,-0.6 -0.507 41.2 170.8 -80.1 138.2 6.3 152.0 20.3 86 85 A S E -LM 67 102C 0 16,-3.1 16,-2.6 -2,-0.2 2,-0.4 -0.911 21.9-136.8-135.9 162.9 3.4 149.7 19.5 87 86 A Q E +LM 66 101C 46 -21,-2.2 -21,-2.8 -2,-0.3 2,-0.3 -0.989 35.2 136.1-130.8 134.8 3.2 145.9 19.3 88 87 A D E - M 0 100C 1 12,-2.0 12,-2.9 -2,-0.4 2,-0.4 -0.942 55.0 -70.8-159.1 178.0 1.5 143.8 16.7 89 88 A T E - 0 0 32 -2,-0.3 -67,-1.1 10,-0.2 2,-0.4 -0.683 45.0-156.4 -84.4 131.0 1.9 140.8 14.5 90 89 A L E -HM 21 97C 0 7,-3.0 7,-4.0 -2,-0.4 2,-0.4 -0.871 8.1-169.1-112.2 139.9 4.4 141.0 11.7 91 90 A S E +HM 20 96C 26 -71,-2.0 -71,-1.6 -2,-0.4 2,-0.4 -0.995 10.7 168.3-130.7 133.9 4.5 139.0 8.5 92 91 A I E > - M 0 95C 8 3,-1.3 3,-2.3 -2,-0.4 2,-0.2 -0.963 69.5 -33.6-144.7 121.0 7.3 138.8 6.0 93 92 A G T 3 S- 0 0 46 -75,-0.5 -88,-0.1 -2,-0.4 -90,-0.0 -0.480 126.7 -29.6 64.3-130.8 7.3 136.2 3.2 94 93 A D T 3 S+ 0 0 116 -90,-0.3 2,-0.3 -2,-0.2 -1,-0.3 0.220 115.7 106.5-102.3 15.9 5.7 133.2 4.8 95 94 A L E < - M 0 92C 9 -3,-2.3 -3,-1.3 -92,-0.1 2,-0.5 -0.692 50.6-163.7 -91.5 147.7 6.9 134.0 8.4 96 95 A T E - M 0 91C 77 -2,-0.3 -5,-0.2 -5,-0.2 -2,-0.0 -0.980 3.7-170.2-132.5 115.6 4.5 135.3 10.9 97 96 A I E - M 0 90C 6 -7,-4.0 -7,-3.0 -2,-0.5 3,-0.4 -0.895 12.4-154.8-113.6 101.2 6.1 136.9 13.9 98 97 A P E + 0 0 44 0, 0.0 -9,-0.2 0, 0.0 -10,-0.0 -0.222 68.8 18.9 -69.7 158.5 3.6 137.6 16.7 99 98 A K E S+ 0 0 150 1,-0.2 2,-0.5 -35,-0.2 -10,-0.2 0.851 77.2 171.0 47.0 49.8 4.0 140.3 19.4 100 99 A Q E - M 0 88C 2 -12,-2.9 -12,-2.0 -3,-0.4 2,-0.3 -0.777 27.0-139.1 -90.3 126.8 6.6 142.3 17.5 101 100 A D E + M 0 87C 45 -2,-0.5 2,-0.3 34,-0.3 -14,-0.2 -0.653 36.7 155.0 -81.7 142.0 7.5 145.8 19.1 102 101 A F E - M 0 86C 1 -16,-2.6 -16,-3.1 -2,-0.3 2,-0.4 -0.974 40.9-103.9-159.1 165.9 7.9 148.5 16.5 103 102 A A E -kM 40 85C 1 -64,-2.3 -62,-1.8 -2,-0.3 2,-0.6 -0.823 17.8-156.8-102.3 135.4 7.7 152.3 16.2 104 103 A E E -kM 41 84C 1 -20,-2.6 -20,-1.8 -2,-0.4 2,-0.5 -0.961 26.4-131.0-107.7 124.2 4.8 154.0 14.5 105 104 A A E +kM 42 83C 0 -64,-2.7 -62,-2.9 -2,-0.6 -22,-0.3 -0.654 29.8 177.2 -83.4 121.3 6.0 157.5 13.4 106 105 A T E S+ 0 0 45 -24,-1.4 -59,-1.2 -2,-0.5 2,-0.3 0.446 80.7 34.2 -96.0 -1.7 4.0 160.6 14.2 107 106 A S E + M 0 82C 33 -25,-1.9 -25,-2.3 -61,-0.2 -1,-0.3 -0.932 64.7 178.2-156.5 125.8 6.7 162.7 12.6 108 107 A E - 0 0 6 -2,-0.3 -58,-0.5 -27,-0.2 -57,-0.2 -0.994 32.4-114.9-134.2 131.3 8.9 162.1 9.6 109 108 A P >> - 0 0 9 0, 0.0 4,-2.5 0, 0.0 5,-0.5 -0.392 22.1-141.6 -65.3 128.7 11.5 164.5 8.1 110 109 A G H >>S+ 0 0 33 2,-0.2 4,-1.6 3,-0.2 5,-0.5 0.896 94.8 43.7 -60.7 -51.2 10.7 165.5 4.5 111 110 A L H 45S+ 0 0 114 1,-0.2 4,-0.2 2,-0.2 -1,-0.2 0.887 118.8 48.3 -65.9 -32.4 14.0 165.5 2.7 112 111 A T H 45S+ 0 0 4 1,-0.1 -2,-0.2 2,-0.1 -1,-0.2 0.911 134.2 2.0 -73.0 -42.6 14.9 162.3 4.4 113 112 A F H ><5S+ 0 0 3 -4,-2.5 3,-1.2 2,-0.1 -3,-0.2 0.640 100.5 91.0-122.8 -20.1 11.7 160.3 3.7 114 113 A A T 3< - 0 0 4 66,-1.9 3,-1.5 -92,-0.2 -1,-0.2 -0.266 43.1-122.1 -64.1 148.5 22.6 143.9 16.1 127 126 A D G > S+ 0 0 73 1,-0.3 3,-1.4 2,-0.2 -1,-0.1 0.632 102.0 82.5 -68.5 -10.9 20.2 144.6 19.0 128 127 A T G 3 S+ 0 0 69 1,-0.3 -1,-0.3 64,-0.1 64,-0.1 0.806 97.1 40.6 -62.0 -30.5 22.9 146.7 20.6 129 128 A I G < S+ 0 0 7 -3,-1.5 2,-0.5 63,-0.2 -92,-0.4 0.178 83.0 125.8-106.8 19.8 22.0 149.7 18.4 130 129 A S X - 0 0 6 -3,-1.4 3,-2.5 -94,-0.1 -92,-0.1 -0.659 66.9-117.4 -78.1 120.6 18.2 149.3 18.6 131 130 A V G > S+ 0 0 21 -2,-0.5 3,-1.6 1,-0.3 -2,-0.1 -0.337 101.7 7.9 -59.0 137.9 16.6 152.5 19.7 132 131 A D G 3 S- 0 0 75 1,-0.3 -1,-0.3 -47,-0.0 3,-0.1 0.623 121.0 -91.2 62.6 12.9 14.7 152.0 23.0 133 132 A K G < - 0 0 174 -3,-2.5 2,-0.3 1,-0.2 -1,-0.3 0.847 66.6-179.6 50.8 39.6 16.4 148.6 22.9 134 133 A V < - 0 0 11 -3,-1.6 -1,-0.2 1,-0.1 -4,-0.0 -0.545 37.3-108.9 -67.7 129.0 13.4 147.2 21.1 135 134 A V - 0 0 76 -2,-0.3 -34,-0.3 -3,-0.1 -1,-0.1 -0.444 42.3-122.9 -59.9 119.5 14.0 143.5 20.4 136 135 A P > - 0 0 2 0, 0.0 4,-2.9 0, 0.0 5,-0.2 -0.243 16.7-108.6 -67.7 157.3 14.5 143.4 16.6 137 136 A P H > S+ 0 0 7 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.894 118.7 48.8 -48.2 -50.3 12.2 141.3 14.3 138 137 A F H > S+ 0 0 9 -15,-0.4 4,-1.9 1,-0.2 5,-0.2 0.915 113.8 46.6 -60.3 -43.6 15.0 138.8 13.5 139 138 A Y H > S+ 0 0 40 1,-0.2 4,-2.7 2,-0.2 -1,-0.2 0.888 111.9 51.5 -64.8 -38.8 15.9 138.4 17.2 140 139 A N H X S+ 0 0 21 -4,-2.9 4,-1.3 2,-0.2 -2,-0.2 0.870 107.5 52.6 -66.3 -37.5 12.2 138.0 18.0 141 140 A A H <>S+ 0 0 3 -4,-2.4 5,-2.6 -5,-0.2 6,-0.4 0.907 111.7 46.0 -64.4 -43.6 11.8 135.3 15.3 142 141 A I H ><5S+ 0 0 30 -4,-1.9 3,-2.4 1,-0.2 -2,-0.2 0.935 109.2 55.2 -64.3 -48.2 14.7 133.3 16.8 143 142 A Q H 3<5S+ 0 0 150 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.784 108.4 49.2 -57.4 -28.3 13.3 133.8 20.4 144 143 A Q T 3<5S- 0 0 63 -4,-1.3 -1,-0.3 -5,-0.1 -2,-0.2 0.237 113.8-118.8 -96.5 14.8 10.0 132.3 19.2 145 144 A D T < 5S+ 0 0 145 -3,-2.4 -3,-0.2 1,-0.1 -2,-0.1 0.838 71.8 135.0 53.4 39.3 11.8 129.3 17.6 146 145 A L < + 0 0 59 -5,-2.6 2,-0.4 -6,-0.1 -4,-0.2 0.585 54.5 65.9 -91.8 -10.3 10.4 130.2 14.2 147 146 A L - 0 0 25 -6,-0.4 25,-0.1 -5,-0.2 3,-0.1 -0.900 67.2-144.7-118.6 145.8 13.7 129.7 12.4 148 147 A D S S+ 0 0 146 -2,-0.4 2,-0.3 24,-0.3 25,-0.1 0.821 89.2 17.7 -70.6 -35.2 15.9 126.6 11.7 149 148 A E S S- 0 0 78 23,-0.3 2,-1.6 2,-0.2 -1,-0.1 -0.970 78.7-112.5-139.4 157.4 19.1 128.6 12.0 150 149 A K S S+ 0 0 103 -2,-0.3 169,-1.9 22,-0.1 168,-1.0 -0.492 84.9 74.0 -88.3 65.3 20.3 131.9 13.4 151 150 A R E -B 317 0A 37 -2,-1.6 21,-2.6 166,-0.2 22,-0.7 -0.980 53.3-159.0-165.9 161.5 21.2 133.7 10.2 152 151 A F E -BC 316 171A 0 164,-1.7 164,-3.4 -2,-0.3 2,-0.3 -0.921 13.7-153.7-141.7 164.0 19.7 135.3 7.2 153 152 A A E -BC 315 170A 0 17,-2.1 17,-2.6 -2,-0.3 2,-0.4 -0.986 4.9-142.6-145.6 155.8 21.1 136.0 3.7 154 153 A F E -BC 314 169A 4 160,-2.7 160,-2.0 -2,-0.3 2,-0.5 -0.966 10.5-177.9-123.8 135.2 20.8 138.4 0.8 155 154 A Y E - C 0 168A 15 13,-2.7 13,-3.2 -2,-0.4 2,-0.5 -0.998 24.3-150.7-120.9 128.6 21.0 137.8 -3.0 156 155 A L E - C 0 167A 4 153,-0.5 11,-0.3 -2,-0.5 10,-0.1 -0.895 6.0-132.5-110.6 128.7 20.6 141.1 -4.8 157 156 A G - 0 0 0 9,-2.6 2,-0.3 -2,-0.5 9,-0.2 -0.137 14.8-149.6 -67.1 168.2 19.1 141.5 -8.3 158 157 A D > > - 0 0 5 7,-0.4 5,-1.6 1,-0.1 3,-0.5 -0.900 13.9-165.9-147.9 111.6 20.8 143.6 -11.0 159 158 A T G > 5S+ 0 0 79 -2,-0.3 3,-1.0 1,-0.2 -1,-0.1 0.803 91.6 64.5 -66.5 -29.2 18.9 145.4 -13.8 160 159 A S G 3 5S+ 0 0 77 1,-0.3 -1,-0.2 2,-0.1 -2,-0.0 0.879 110.4 38.0 -62.9 -33.7 22.2 145.9 -15.7 161 159AA K G < 5S- 0 0 140 -3,-0.5 -1,-0.3 0, 0.0 -2,-0.2 0.354 112.5-124.8 -95.1 3.0 22.4 142.1 -16.0 162 159BA D T < 5 - 0 0 139 -3,-1.0 -3,-0.2 -4,-0.2 -2,-0.1 0.939 36.1-167.0 54.5 55.8 18.6 141.8 -16.6 163 159CA T < - 0 0 43 -5,-1.6 -1,-0.1 1,-0.1 -6,-0.0 -0.373 32.9-110.7 -73.2 154.8 18.0 139.3 -13.8 164 160 A E S S- 0 0 194 -2,-0.0 2,-0.2 2,-0.0 -1,-0.1 0.804 94.7 -5.3 -51.0 -36.2 14.6 137.6 -13.6 165 161 A N S S- 0 0 80 -7,-0.0 -7,-0.4 -157,-0.0 -2,-0.1 -0.863 82.8 -86.0-149.3-176.5 13.7 139.6 -10.4 166 162 A G S S- 0 0 10 -159,-0.6 -9,-2.6 -2,-0.2 2,-0.3 0.519 77.0 -96.2 -79.2 -5.0 15.0 142.1 -7.9 167 163 A G E - C 0 156A 3 -11,-0.3 -160,-1.6 -160,-0.1 2,-0.3 -0.783 35.4 -94.9 125.8-167.8 16.6 139.5 -5.6 168 164 A E E -AC 6 155A 25 -13,-3.2 -13,-2.7 -2,-0.3 2,-0.4 -0.970 9.8-156.8-161.2 137.4 15.9 137.6 -2.4 169 165 A A E -AC 5 154A 0 -164,-2.6 -164,-3.0 -2,-0.3 2,-0.5 -0.954 17.9-158.7-113.3 136.8 16.4 137.6 1.3 170 166 A T E -AC 4 153A 0 -17,-2.6 -17,-2.1 -2,-0.4 2,-0.5 -0.969 1.0-158.8-120.1 125.0 16.3 134.3 3.2 171 167 A F E S+AC 3 152A 14 -168,-2.4 -168,-3.0 -2,-0.5 -19,-0.2 -0.897 75.8 13.2-106.1 128.2 15.6 134.1 6.9 172 168 A G S S+ 0 0 0 -21,-2.6 -24,-0.3 -2,-0.5 -23,-0.3 0.651 131.1 12.6 87.3 17.9 16.6 131.1 8.9 173 169 A G S S- 0 0 0 -22,-0.7 2,-0.3 -3,-0.4 -1,-0.3 -0.971 79.3 -98.8 171.5-167.5 18.9 129.7 6.2 174 170 A I - 0 0 8 -2,-0.3 2,-0.6 -3,-0.1 3,-0.1 -0.833 26.0-115.1-134.8 172.2 20.6 130.5 3.0 175 171 A D > - 0 0 23 -2,-0.3 3,-1.9 -174,-0.1 4,-0.2 -0.905 17.5-168.1-117.0 103.7 19.9 129.8 -0.7 176 172 A E G > S+ 0 0 131 -2,-0.6 3,-0.9 1,-0.3 -1,-0.1 0.724 86.2 64.3 -59.8 -24.5 22.5 127.6 -2.3 177 173 A S G 3 S+ 0 0 65 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.621 93.2 63.1 -77.0 -10.8 21.1 128.4 -5.7 178 174 A K G < S+ 0 0 34 -3,-1.9 151,-2.4 150,-0.1 2,-0.3 0.489 107.5 28.3 -95.0 -1.1 22.1 132.1 -5.4 179 175 A F E < -D 328 0A 20 -3,-0.9 2,-0.3 149,-0.3 149,-0.2 -0.933 60.6-146.7-148.7 171.9 25.9 131.7 -5.1 180 176 A K E +D 327 0A 131 147,-2.4 147,-0.7 -2,-0.3 -3,-0.0 -0.942 57.5 22.0-139.0 159.6 28.8 129.5 -6.1 181 177 A G E S- 0 0 62 -2,-0.3 2,-0.1 145,-0.1 -2,-0.0 -0.239 99.6 -31.8 80.3-170.5 32.1 128.6 -4.6 182 178 A D E - 0 0 149 1,-0.0 2,-0.5 144,-0.0 145,-0.4 -0.418 56.0-119.6 -83.0 161.3 33.0 128.7 -0.9 183 179 A I E - 0 0 38 143,-0.1 2,-0.6 -2,-0.1 143,-0.2 -0.848 23.6-147.2 -96.0 128.7 31.6 131.1 1.7 184 180 A T E -D 325 0A 39 141,-3.0 141,-2.3 -2,-0.5 2,-0.3 -0.908 16.4-141.5-100.4 122.8 34.4 133.1 3.2 185 181 A W E -D 324 0A 90 -2,-0.6 139,-0.2 139,-0.2 137,-0.0 -0.655 15.1-168.1 -89.0 141.2 33.5 133.9 6.8 186 182 A L E -D 323 0A 0 137,-3.2 137,-3.2 -2,-0.3 3,-0.1 -0.924 20.7-133.6-128.1 102.1 34.3 137.3 8.4 187 183 A P E -D 322 0A 78 0, 0.0 10,-0.4 0, 0.0 135,-0.3 -0.292 35.8-100.0 -57.3 138.1 34.0 137.5 12.2 188 184 A V - 0 0 21 133,-2.8 8,-0.2 1,-0.2 3,-0.2 -0.391 26.9-155.5 -61.7 125.0 32.1 140.6 13.3 189 185 A R S S+ 0 0 76 6,-3.5 2,-0.3 1,-0.3 7,-0.2 0.906 80.8 2.9 -68.6 -44.7 34.6 143.3 14.4 190 186 A R S >S- 0 0 58 5,-0.5 2,-1.0 3,-0.2 5,-0.8 -0.990 77.9-121.6-143.2 138.5 32.0 145.1 16.6 191 187 A K B 5S+O 194 0E 109 -2,-0.3 3,-0.1 -3,-0.2 -66,-0.0 -0.708 89.3 68.2 -87.6 102.5 28.4 144.0 17.2 192 188 A A T 5S+ 0 0 0 1,-1.8 -66,-1.9 -2,-1.0 -63,-0.2 -0.188 104.4 26.7-170.3 -79.8 26.2 147.0 16.1 193 189 A Y T 5S- 0 0 4 -68,-0.2 2,-2.0 -3,-0.2 -1,-1.8 -0.434 103.3 -96.5 -81.8 171.4 26.5 147.2 12.3 194 190 A W B 5 -O 191 0E 2 -160,-0.5 23,-2.7 23,-0.3 2,-0.4 -0.663 68.8-179.2 -89.1 79.6 27.4 143.9 10.7 195 191 A E E < -P 216 0F 0 -2,-2.0 -6,-3.5 -5,-0.8 -5,-0.5 -0.725 19.2-174.9 -95.0 130.9 30.9 145.2 10.8 196 192 A V E -P 215 0F 0 19,-2.5 19,-2.2 -2,-0.4 2,-0.5 -0.758 41.3 -86.3-115.7 164.2 34.1 143.4 9.5 197 193 A K E -P 214 0F 98 -10,-0.4 69,-2.1 -2,-0.3 2,-1.3 -0.604 34.8-152.3 -72.7 117.8 37.8 144.4 9.7 198 194 A F E +T 265 0G 2 15,-1.8 15,-0.4 -2,-0.5 67,-0.2 -0.745 28.3 164.6 -93.9 89.7 38.5 146.7 6.8 199 195 A E E + 0 0 72 65,-1.9 11,-2.0 -2,-1.3 2,-0.3 0.681 54.4 1.8 -86.0 -19.1 42.2 145.8 6.4 200 196 A G E -TU 264 209G 0 64,-1.2 64,-3.2 9,-0.3 2,-0.4 -0.967 49.8-159.2-169.0 150.8 43.0 147.1 3.0 201 197 A I E +TU 263 208G 6 7,-2.1 7,-2.6 -2,-0.3 2,-0.3 -0.982 16.8 179.3-133.8 143.4 41.8 148.9 -0.1 202 198 A G E -TU 262 207G 3 60,-2.1 60,-3.5 -2,-0.4 2,-0.5 -1.000 19.8-160.3-149.9 146.7 43.1 148.9 -3.5 203 199 A L E > -TU 261 206G 2 3,-2.3 3,-2.1 -2,-0.3 2,-0.3 -0.976 69.5 -49.8-126.9 115.5 42.5 150.4 -7.0 204 200 A G T 3 S- 0 0 25 56,-2.8 54,-0.0 -2,-0.5 58,-0.0 -0.429 126.3 -11.2 63.2-118.2 44.1 148.6 -9.9 205 201 A D T 3 S+ 0 0 174 -2,-0.3 2,-0.4 -3,-0.1 -1,-0.3 0.589 120.3 85.2 -91.9 -14.4 47.7 148.2 -9.1 206 202 A E E < +U 203 0G 87 -3,-2.1 -3,-2.3 2,-0.0 2,-0.3 -0.770 51.6 166.1 -92.7 135.6 47.8 150.4 -6.0 207 203 A Y E -U 202 0G 88 -2,-0.4 2,-0.4 -5,-0.3 -5,-0.3 -0.965 10.8-172.7-149.6 128.9 46.8 148.9 -2.7 208 204 A A E -U 201 0G 57 -7,-2.6 -7,-2.1 -2,-0.3 2,-0.2 -0.963 22.4-124.2-128.0 142.2 47.3 150.3 0.8 209 205 A E E -U 200 0G 147 -2,-0.4 2,-0.3 -9,-0.2 -9,-0.3 -0.510 26.5-144.4 -79.7 150.4 46.7 148.7 4.2 210 206 A L - 0 0 27 -11,-2.0 2,-0.4 -2,-0.2 3,-0.2 -0.860 3.9-134.8-117.4 152.8 44.4 150.6 6.6 211 207 A E S S- 0 0 148 -2,-0.3 -12,-0.0 1,-0.2 -11,-0.0 -0.903 78.1 -13.0-111.3 134.6 44.7 150.9 10.4 212 208 A S S S+ 0 0 88 -2,-0.4 2,-0.4 1,-0.2 -1,-0.2 0.843 91.2 149.7 47.6 41.0 41.7 150.5 12.8 213 209 A H - 0 0 33 -15,-0.4 -15,-1.8 -3,-0.2 2,-0.3 -0.840 27.3-165.5-103.7 144.4 39.2 150.7 10.0 214 210 A G E -Pq 197 301F 0 86,-1.6 88,-2.3 -2,-0.4 2,-0.4 -0.839 7.4-151.1-122.0 161.3 35.8 148.9 10.0 215 212 A A E -Pq 196 302F 0 -19,-2.2 -19,-2.5 -2,-0.3 2,-0.5 -0.943 7.1-148.7-138.7 115.1 33.4 148.1 7.2 216 213 A A E -Pq 195 303F 1 86,-2.4 88,-2.9 -2,-0.4 2,-1.0 -0.711 14.4-139.9 -82.5 123.6 29.6 147.8 7.8 217 214 A I E - q 0 304F 1 -23,-2.7 2,-0.5 -2,-0.5 -23,-0.3 -0.778 33.6-175.6 -86.3 109.0 28.0 145.3 5.3 218 215 A D > - 0 0 1 86,-2.5 3,-1.0 -2,-1.0 88,-0.3 -0.880 32.8-179.8-122.0 105.8 24.9 147.3 4.6 219 216 A T T 3 S+ 0 0 5 -2,-0.5 -204,-0.2 1,-0.2 87,-0.2 0.731 76.6 78.5 -67.7 -22.2 21.9 146.1 2.5 220 217 A G T 3 S+ 0 0 11 -189,-0.1 2,-0.3 -206,-0.1 -1,-0.2 0.512 95.0 37.9 -68.3 -9.6 20.1 149.4 3.2 221 218 A T < - 0 0 3 -3,-1.0 85,-3.0 2,-0.2 86,-0.1 -0.969 61.6-146.6-138.6 152.0 22.0 151.7 0.7 222 219 A S S S+ 0 0 1 -209,-0.5 85,-1.2 -2,-0.3 86,-0.1 0.566 75.6 96.4 -91.5 -10.0 23.3 151.1 -2.7 223 220 A L - 0 0 0 -210,-0.2 82,-1.6 83,-0.1 2,-0.4 -0.231 65.1-145.0 -75.6 166.8 26.2 153.5 -2.0 224 221 A I E -rS 289 304F 0 64,-2.4 66,-2.3 80,-0.2 2,-0.3 -0.946 21.9-162.2-129.8 105.4 29.8 152.5 -0.8 225 222 A T E +rS 290 303F 0 78,-2.7 78,-1.1 -2,-0.4 64,-0.1 -0.710 11.1 177.6 -96.2 148.0 31.1 155.2 1.6 226 223 A L E -r 291 0F 0 64,-2.1 66,-2.5 -2,-0.3 76,-0.1 -0.937 46.2 -76.6-139.8 156.7 34.7 155.6 2.5 227 224 A P >> - 0 0 17 0, 0.0 4,-2.6 0, 0.0 3,-0.8 -0.330 57.3-110.4 -51.7 138.0 36.6 158.1 4.6 228 225 A S H 3> S+ 0 0 42 1,-0.3 4,-3.3 2,-0.2 5,-0.4 0.846 115.6 56.2 -44.2 -49.6 36.8 161.3 2.5 229 226 A G H 3> S+ 0 0 56 1,-0.2 4,-2.0 2,-0.2 -1,-0.3 0.925 115.0 39.9 -50.6 -47.5 40.5 161.1 1.8 230 227 A L H <> S+ 0 0 34 -3,-0.8 4,-2.7 2,-0.2 5,-0.2 0.956 115.7 50.0 -66.0 -52.3 40.0 157.6 0.3 231 228 A A H X S+ 0 0 0 -4,-2.6 4,-2.6 1,-0.2 5,-0.2 0.926 114.0 45.1 -55.1 -47.4 36.7 158.3 -1.4 232 229 A E H X S+ 0 0 87 -4,-3.3 4,-2.4 -5,-0.2 5,-0.3 0.909 111.1 52.7 -65.0 -41.4 38.1 161.5 -3.1 233 230 A M H X S+ 0 0 91 -4,-2.0 4,-2.3 -5,-0.4 -1,-0.2 0.946 114.4 43.4 -58.9 -47.0 41.4 159.8 -4.2 234 231 A I H X S+ 0 0 2 -4,-2.7 4,-2.0 2,-0.2 -2,-0.2 0.894 112.5 50.0 -67.9 -42.6 39.4 157.0 -5.8 235 232 A N H <>S+ 0 0 1 -4,-2.6 5,-3.2 -5,-0.2 4,-0.3 0.924 113.0 47.2 -63.9 -41.1 36.8 159.1 -7.5 236 233 A A H ><5S+ 0 0 74 -4,-2.4 3,-1.7 -5,-0.2 -2,-0.2 0.949 110.3 54.8 -62.1 -46.0 39.5 161.4 -9.0 237 234 A E H 3<5S+ 0 0 87 -4,-2.3 -1,-0.2 -5,-0.3 -2,-0.2 0.835 111.3 42.5 -55.5 -39.6 41.4 158.3 -10.0 238 235 A I T 3<5S- 0 0 2 -4,-2.0 -1,-0.3 2,-0.1 -2,-0.2 0.294 119.2-106.3 -93.8 9.8 38.4 156.8 -12.0 239 236 A G T < 5 + 0 0 51 -3,-1.7 2,-0.7 -4,-0.3 12,-0.3 0.762 66.7 152.1 74.1 25.4 37.5 160.2 -13.5 240 237 A A < - 0 0 5 -5,-3.2 2,-0.4 -6,-0.2 -1,-0.2 -0.812 19.8-178.0 -92.7 118.2 34.4 160.7 -11.4 241 238 A K E -W 249 0H 149 8,-2.6 8,-2.5 -2,-0.7 2,-1.2 -0.931 31.7-121.7-120.0 140.9 33.7 164.4 -10.9 242 239 A K E +W 248 0H 109 -2,-0.4 6,-0.2 6,-0.3 -2,-0.0 -0.685 48.2 174.3 -82.7 97.4 31.0 166.0 -8.9 243 240 A G > - 0 0 34 4,-1.3 3,-2.0 -2,-1.2 -1,-0.0 0.095 49.2 -59.7 -89.8-159.0 29.1 168.0 -11.5 244 241 A W T 3 S+ 0 0 216 1,-0.3 -2,-0.1 2,-0.1 -1,-0.0 0.713 125.0 65.4 -59.3 -23.3 26.0 170.1 -11.7 245 242 A T T 3 S- 0 0 36 2,-0.2 -1,-0.3 1,-0.1 3,-0.1 0.525 109.0-118.2 -79.0 -5.3 23.8 167.2 -10.7 246 243 A G S < S+ 0 0 25 -3,-2.0 2,-0.3 1,-0.3 -2,-0.1 0.499 82.9 98.7 82.8 1.4 25.3 167.0 -7.2 247 244 A Q S S- 0 0 9 -6,-0.1 -4,-1.3 94,-0.0 2,-0.6 -0.830 82.1-107.9-118.8 157.5 26.6 163.5 -7.8 248 245 A Y E +W 242 0H 30 39,-0.3 39,-2.5 -2,-0.3 2,-0.3 -0.777 49.5 176.7 -83.7 122.6 30.1 162.2 -8.8 249 246 A T E -WX 241 286H 41 -8,-2.5 -8,-2.6 -2,-0.6 2,-0.3 -0.880 12.7-169.6-126.7 159.6 29.6 161.0 -12.4 250 247 A L E - X 0 285H 15 35,-2.5 35,-0.8 -2,-0.3 2,-0.7 -0.906 39.0 -79.3-142.0 167.9 32.0 159.6 -15.1 251 248 A D > - 0 0 94 -12,-0.3 3,-1.8 -2,-0.3 4,-0.5 -0.608 35.0-145.7 -76.2 113.9 32.1 158.8 -18.8 252 249 A b G > S+ 0 0 14 -2,-0.7 3,-0.8 1,-0.3 4,-0.2 0.740 95.7 59.3 -51.0 -29.0 30.3 155.5 -19.3 253 250 A N G 3 S+ 0 0 114 1,-0.2 -1,-0.3 2,-0.1 -2,-0.1 0.110 92.8 67.4 -93.2 27.9 32.6 154.5 -22.1 254 251 A T G X S+ 0 0 44 -3,-1.8 3,-2.2 2,-0.1 -1,-0.2 0.514 76.4 89.3-110.4 -19.2 35.7 154.7 -19.9 255 252 A R G X S+ 0 0 24 -3,-0.8 3,-1.5 -4,-0.5 -2,-0.1 0.796 75.3 63.0 -49.9 -39.3 34.5 151.7 -17.9 256 253 A D G 3 S+ 0 0 121 1,-0.3 -1,-0.3 -4,-0.2 -2,-0.1 0.665 112.4 36.9 -65.8 -15.9 36.2 149.2 -20.1 257 254 A N G < S+ 0 0 127 -3,-2.2 -1,-0.3 2,-0.1 -2,-0.2 0.041 91.7 108.5-124.8 28.8 39.6 150.6 -19.2 258 255 A L S < S- 0 0 23 -3,-1.5 -20,-0.1 1,-0.1 -54,-0.0 -0.807 70.2-109.8-100.6 145.0 39.0 151.5 -15.5 259 256 A P - 0 0 38 0, 0.0 2,-0.2 0, 0.0 -1,-0.1 -0.159 30.1-100.9 -71.3 166.3 40.7 149.4 -12.8 260 257 A D - 0 0 73 13,-0.1 -56,-2.8 14,-0.1 2,-0.5 -0.591 28.6-128.6 -87.7 148.5 39.1 147.0 -10.3 261 258 A L E -TV 203 272G 0 11,-3.1 11,-2.3 -2,-0.2 2,-0.5 -0.858 21.6-156.1-100.4 130.8 38.4 148.0 -6.7 262 259 A I E -TV 202 271G 33 -60,-3.5 -60,-2.1 -2,-0.5 2,-0.5 -0.938 7.1-167.4-114.3 126.2 39.7 145.7 -4.1 263 260 A F E -TV 201 270G 0 7,-3.3 7,-3.2 -2,-0.5 2,-0.7 -0.940 6.8-157.2-110.9 126.8 38.3 145.4 -0.6 264 261 A N E +TV 200 269G 16 -64,-3.2 -65,-1.9 -2,-0.5 -64,-1.2 -0.897 14.6 178.0-107.2 109.8 40.3 143.5 2.1 265 262 A F E > S-TV 198 268G 0 3,-2.5 3,-2.3 -2,-0.7 -67,-0.2 -0.956 71.5 -20.6-112.9 123.2 38.1 142.3 4.9 266 263 A N T 3 S- 0 0 30 -69,-2.1 -1,-0.1 -2,-0.5 -68,-0.1 0.699 130.1 -48.2 54.1 25.3 39.7 140.2 7.7 267 264 A G T 3 S+ 0 0 44 1,-0.3 2,-0.4 -70,-0.3 -1,-0.3 0.384 116.9 109.0 99.4 -4.3 42.6 139.3 5.4 268 265 A Y E < -V 265 0G 118 -3,-2.3 -3,-2.5 -84,-0.0 2,-0.4 -0.882 62.9-130.4-109.6 141.8 40.5 138.3 2.4 269 266 A N E -V 264 0G 90 -2,-0.4 2,-0.4 -5,-0.2 -5,-0.2 -0.729 20.2-175.1 -93.3 132.8 40.2 140.3 -0.9 270 267 A F E -V 263 0G 9 -7,-3.2 -7,-3.3 -2,-0.4 2,-0.4 -0.994 13.3-161.7-126.2 126.6 36.9 141.0 -2.5 271 268 A T E +V 262 0G 34 -2,-0.4 2,-0.3 -9,-0.2 -9,-0.2 -0.838 16.1 179.2-119.6 145.8 36.8 142.7 -5.8 272 269 A I E -V 261 0G 0 -11,-2.3 -11,-3.1 -2,-0.4 36,-0.1 -0.989 20.1-134.9-137.8 147.4 34.3 144.7 -7.9 273 270 A G >> - 0 0 9 -2,-0.3 3,-3.1 -13,-0.2 4,-2.3 -0.419 36.9 -88.6 -97.0 175.3 34.8 146.3 -11.3 274 271 A P T 34 S+ 0 0 10 0, 0.0 4,-0.2 0, 0.0 -19,-0.1 0.659 125.2 61.2 -55.5 -18.3 33.8 149.7 -12.9 275 272 A Y T 34 S+ 0 0 99 2,-0.1 5,-0.2 1,-0.1 -115,-0.1 0.548 113.4 36.0 -85.8 -7.8 30.5 148.2 -13.8 276 273 A D T <4 S+ 0 0 23 -3,-3.1 -1,-0.1 3,-0.1 34,-0.1 0.707 113.4 51.4-113.1 -33.7 29.7 147.6 -10.2 277 274 A Y S < S+ 0 0 2 -4,-2.3 11,-2.6 10,-0.1 12,-0.5 0.441 114.3 50.4 -86.3 4.9 31.2 150.5 -8.4 278 275 A T E S-Y 287 0H 3 -5,-0.3 2,-0.5 9,-0.3 9,-0.2 -0.932 77.8-140.8-130.3 158.7 29.4 152.9 -10.8 279 276 A L E -Y 286 0H 7 7,-2.9 7,-2.9 -2,-0.3 2,-0.5 -0.984 9.6-142.7-127.8 126.8 25.7 152.8 -11.7 280 277 A E E +Y 285 0H 104 -2,-0.5 2,-0.3 5,-0.2 5,-0.2 -0.775 31.8 153.4 -92.9 121.6 24.4 153.4 -15.2 281 278 A V E > -Y 284 0H 11 3,-2.7 3,-2.8 -2,-0.5 -2,-0.1 -0.990 65.5 -3.1-147.8 140.5 21.1 155.4 -15.6 282 279 A S T 3 S- 0 0 56 -2,-0.3 3,-0.1 1,-0.3 -1,-0.1 0.801 128.7 -56.7 49.7 34.4 19.7 157.6 -18.4 283 280 A G T 3 S+ 0 0 62 1,-0.3 -1,-0.3 -31,-0.0 -31,-0.3 0.340 118.9 107.0 82.7 -8.9 22.9 157.1 -20.3 284 281 A S E < - Y 0 281H 37 -3,-2.8 -3,-2.7 -33,-0.1 2,-0.5 -0.648 62.9-136.6-103.4 161.5 25.0 158.5 -17.5 285 282 A b E -XY 250 280H 0 -35,-0.8 -35,-2.5 -5,-0.2 2,-0.5 -0.941 16.2-166.6-122.8 109.5 27.3 156.7 -15.0 286 283 A I E -XY 249 279H 0 -7,-2.9 -7,-2.9 -2,-0.5 -37,-0.3 -0.815 20.5-128.6 -96.5 128.2 27.1 157.7 -11.3 287 284 A S E - Y 0 278H 4 -39,-2.5 -39,-0.3 -2,-0.5 -9,-0.3 -0.479 6.1-153.2 -72.4 144.3 29.9 156.6 -9.0 288 285 A A + 0 0 1 -11,-2.6 -64,-2.4 -2,-0.1 2,-0.6 0.550 64.2 110.8 -92.1 -8.8 28.7 154.8 -5.9 289 286 A I E -r 224 0F 0 -12,-0.5 -64,-0.2 -66,-0.2 -41,-0.1 -0.564 49.5-176.5 -72.3 116.5 31.8 155.9 -4.0 290 287 A T E -r 225 0F 11 -66,-2.3 -64,-2.1 -2,-0.6 2,-0.2 -0.957 25.9-127.4-122.7 127.4 30.8 158.5 -1.4 291 288 A P E +r 226 0F 35 0, 0.0 2,-0.3 0, 0.0 -66,-0.1 -0.507 42.2 155.2 -70.7 128.4 33.0 160.5 1.0 292 289 A M - 0 0 11 -66,-2.5 2,-0.5 -2,-0.2 9,-0.2 -0.862 24.0-163.3-159.1 123.1 31.8 160.1 4.5 293 290 A D - 0 0 98 -2,-0.3 9,-0.1 -66,-0.2 6,-0.0 -0.943 3.5-163.6-112.0 125.2 33.6 160.5 7.8 294 291 A F - 0 0 17 -2,-0.5 7,-0.1 7,-0.2 2,-0.1 -0.892 22.8-124.9-105.2 136.3 32.3 159.2 11.0 295 292 A P >> - 0 0 98 0, 0.0 4,-1.8 0, 0.0 3,-0.8 -0.357 48.9 -53.6 -75.0 158.8 33.9 160.5 14.3 296 293 A E T 34 S+ 0 0 146 1,-0.3 60,-0.0 2,-0.3 0, 0.0 -0.318 118.7 37.6 -61.1 155.8 35.3 158.2 16.8 297 294 A P T 34 S+ 0 0 41 0, 0.0 -1,-0.3 0, 0.0 -3,-0.0 -0.986 130.7 35.0 -79.2 -13.8 34.4 155.8 18.3 298 295 A V T <4 S+ 0 0 2 -3,-0.8 -2,-0.3 54,-0.1 -84,-0.1 0.983 103.2 93.6 -63.0 -64.6 32.5 154.8 15.2 299 296 A G < + 0 0 4 -4,-1.8 2,-0.1 2,-0.1 -6,-0.1 -0.222 39.9 70.2 -72.7 167.3 34.9 155.9 12.4 300 297 A P S S+ 0 0 35 0, 0.0 -86,-1.6 0, 0.0 2,-0.3 0.409 83.5 138.8 -71.9 134.4 37.0 155.3 10.6 301 298 A L E -q 214 0F 1 -9,-0.2 2,-0.3 -88,-0.2 -86,-0.2 -0.998 42.2-149.6-149.0 141.1 34.4 153.2 8.9 302 299 A A E -q 215 0F 0 -88,-2.3 -86,-2.4 -2,-0.3 2,-0.6 -0.840 14.7-142.0-106.9 147.1 33.2 152.4 5.4 303 300 A I E -qS 216 225F 0 -78,-1.1 -78,-2.7 -2,-0.3 2,-0.8 -0.964 16.4-160.0-111.3 119.4 29.6 151.6 4.6 304 301 A V E +qS 217 224F 0 -88,-2.9 -86,-2.5 -2,-0.6 -80,-0.2 -0.868 21.5 169.8-109.7 102.8 29.5 148.9 2.0 305 302 A G >> - 0 0 0 -82,-1.6 4,-2.2 -2,-0.8 3,-1.8 0.064 48.2 -51.4 -96.7-157.6 26.2 148.8 0.2 306 303 A D H 3> S+ 0 0 1 -85,-3.0 4,-1.8 -88,-0.3 -84,-0.2 0.659 119.0 68.8 -56.4 -24.2 24.4 147.2 -2.7 307 304 A A H 34 S+ 0 0 1 -85,-1.2 -1,-0.3 -84,-0.2 4,-0.2 0.880 114.5 30.9 -66.0 -32.2 26.9 148.2 -5.3 308 305 A F H X> S+ 0 0 0 -3,-1.8 3,-1.6 -85,-0.2 4,-1.1 0.878 117.4 56.3 -86.9 -45.2 29.3 145.7 -3.7 309 306 A L H 3< S+ 0 0 2 -4,-2.2 -153,-0.5 1,-0.3 -2,-0.2 0.682 90.9 72.3 -62.3 -21.6 26.6 143.3 -2.5 310 307 A R T 3< S+ 0 0 12 -4,-1.8 -1,-0.3 -5,-0.2 -2,-0.1 0.819 106.6 38.9 -62.9 -29.3 25.3 142.8 -6.0 311 308 A K T <4 S+ 0 0 47 -3,-1.6 17,-2.3 -4,-0.2 2,-0.5 0.762 116.8 53.9 -90.7 -28.2 28.5 140.8 -6.7 312 309 A Y E < S- E 0 327A 25 -4,-1.1 15,-0.2 15,-0.2 -1,-0.2 -0.917 74.2-139.7-119.5 112.9 28.7 139.0 -3.4 313 310 A Y E - E 0 326A 0 13,-1.6 13,-2.0 -2,-0.5 2,-0.4 -0.386 32.1-150.1 -57.8 137.2 25.9 136.9 -1.9 314 311 A S E -BE 154 325A 0 -160,-2.0 -160,-2.7 11,-0.2 2,-0.4 -0.957 16.4-164.9-124.6 139.9 26.0 137.8 1.8 315 312 A I E -BE 153 324A 0 9,-3.0 9,-3.2 -2,-0.4 2,-0.7 -0.967 7.8-155.3-121.6 134.6 25.1 135.8 4.9 316 313 A Y E -BE 152 323A 0 -164,-3.4 -164,-1.7 -2,-0.4 2,-0.9 -0.913 11.7-171.5-116.4 101.9 24.6 137.3 8.3 317 314 A D E > +BE 151 322A 25 5,-2.4 5,-2.3 -2,-0.7 4,-0.4 -0.808 16.5 168.6 -99.6 95.8 25.2 134.7 10.9 318 315 A L T > 5S+ 0 0 15 -168,-1.0 3,-2.0 -2,-0.9 -1,-0.2 0.963 77.8 65.7 -61.9 -53.2 24.2 136.0 14.3 319 316 A G T 3 5S+ 0 0 40 -169,-1.9 -1,-0.2 1,-0.3 -168,-0.1 0.747 119.9 22.0 -37.4 -47.5 24.6 132.4 15.7 320 317 A N T 3 5S- 0 0 116 -170,-0.3 -1,-0.3 2,-0.2 -2,-0.2 0.308 105.3-124.0-110.8 8.2 28.3 132.6 15.0 321 318 A N T < 5 + 0 0 49 -3,-2.0 -133,-2.8 -4,-0.4 2,-0.3 0.916 69.6 117.4 48.2 55.8 28.7 136.4 14.9 322 319 A A E < -DE 187 317A 3 -5,-2.3 -5,-2.4 -135,-0.3 2,-0.5 -0.992 61.6-131.1-148.6 153.3 30.1 136.5 11.4 323 320 A V E -DE 186 316A 0 -137,-3.2 -137,-3.2 -2,-0.3 2,-0.4 -0.900 24.5-157.2-103.5 135.0 29.4 137.8 8.0 324 321 A G E -DE 185 315A 0 -9,-3.2 -9,-3.0 -2,-0.5 2,-0.4 -0.947 7.4-169.5-115.3 135.2 29.8 135.3 5.2 325 322 A L E +DE 184 314A 1 -141,-2.3 -141,-3.0 -2,-0.4 2,-0.3 -0.977 10.1 167.2-124.3 137.5 30.5 136.3 1.6 326 323 A A E - E 0 313A 3 -13,-2.0 -13,-1.6 -2,-0.4 2,-0.3 -0.955 48.5 -85.3-142.0 155.5 30.4 134.1 -1.6 327 324 A K E -DE 180 312A 69 -147,-0.7 -147,-2.4 -145,-0.4 -15,-0.2 -0.502 50.8-129.0 -64.8 121.9 30.4 135.0 -5.3 328 325 A A E D 179 0A 2 -17,-2.3 -149,-0.3 -2,-0.3 -1,-0.1 -0.364 360.0 360.0 -72.4 153.0 26.7 135.6 -6.3 329 326 A I 0 0 131 -151,-2.4 -150,-0.1 -2,-0.1 -1,-0.1 0.708 360.0 360.0 -68.2 360.0 25.1 133.9 -9.2 330 !* 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 331 2 B N > 0 0 77 0, 0.0 4,-2.8 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 42.3 17.5 162.0 -17.4 332 3 B T H > + 0 0 69 2,-0.2 4,-3.1 1,-0.2 5,-0.2 0.835 360.0 54.3 -66.6 -31.5 14.8 161.4 -14.9 333 4 B D H > S+ 0 0 79 2,-0.2 4,-3.1 1,-0.2 -1,-0.2 0.971 113.6 46.1 -61.4 -46.4 15.9 157.8 -14.0 334 5 B Q H > S+ 0 0 11 1,-0.2 4,-2.8 2,-0.2 -2,-0.2 0.920 112.9 49.0 -58.0 -43.5 19.2 159.5 -13.3 335 6 B Q H X S+ 0 0 96 -4,-2.8 4,-2.2 1,-0.2 -1,-0.2 0.888 111.1 50.7 -64.0 -38.6 17.4 162.3 -11.4 336 7 B K H X S+ 0 0 72 -4,-3.1 4,-2.4 2,-0.2 -2,-0.2 0.929 111.0 47.2 -66.4 -44.8 15.5 159.7 -9.4 337 8 B V H X S+ 0 0 0 -4,-3.1 4,-3.0 2,-0.2 -2,-0.2 0.949 111.2 51.6 -62.4 -43.2 18.7 157.8 -8.5 338 9 B S H X S+ 0 0 13 -4,-2.8 4,-2.7 1,-0.2 -1,-0.2 0.920 108.5 52.3 -58.5 -42.9 20.4 161.0 -7.5 339 10 B E H X S+ 0 0 92 -4,-2.2 4,-2.0 1,-0.2 5,-0.3 0.942 109.6 48.4 -57.8 -49.2 17.4 161.8 -5.3 340 11 B I H X S+ 0 0 15 -4,-2.4 4,-2.0 1,-0.2 -2,-0.2 0.911 111.4 51.6 -60.2 -40.5 17.7 158.4 -3.6 341 12 B F H X S+ 0 0 2 -4,-3.0 4,-2.2 2,-0.2 -2,-0.2 0.942 107.2 51.1 -64.1 -44.7 21.4 159.0 -3.1 342 13 B Q H X S+ 0 0 92 -4,-2.7 4,-1.6 1,-0.2 -2,-0.2 0.939 114.2 42.5 -57.2 -50.1 21.1 162.4 -1.4 343 14 B S H X S+ 0 0 21 -4,-2.0 4,-2.0 1,-0.2 -1,-0.2 0.843 110.1 58.1 -69.3 -29.3 18.5 161.2 1.1 344 15 B S H X S+ 0 0 11 -4,-2.0 4,-3.2 -5,-0.3 -1,-0.2 0.912 104.0 52.2 -65.0 -41.6 20.5 158.0 1.7 345 16 B K H X S+ 0 0 38 -4,-2.2 4,-2.1 1,-0.2 -1,-0.2 0.929 108.7 49.7 -59.9 -45.7 23.5 160.0 2.8 346 17 B E H X S+ 0 0 24 -4,-1.6 4,-2.1 1,-0.2 -269,-0.3 0.900 114.0 46.8 -60.2 -41.2 21.5 162.0 5.3 347 18 B K H X S+ 0 0 21 -4,-2.0 4,-3.0 2,-0.2 5,-0.3 0.928 108.8 52.8 -68.4 -44.1 20.1 158.8 6.7 348 19 B L H X S+ 0 0 6 -4,-3.2 4,-1.7 1,-0.2 -2,-0.2 0.899 111.3 49.0 -57.7 -37.8 23.5 157.0 6.9 349 20 B Q H X S+ 0 0 111 -4,-2.1 4,-1.1 -5,-0.2 -1,-0.2 0.915 112.2 46.9 -69.2 -42.9 24.8 160.0 8.8 350 21 B G H >X S+ 0 0 7 -4,-2.1 4,-1.2 1,-0.2 3,-0.6 0.931 111.3 50.5 -65.5 -45.0 21.9 160.0 11.2 351 22 B D H 3X S+ 0 0 11 -4,-3.0 4,-1.9 1,-0.2 -1,-0.2 0.825 104.5 58.6 -63.7 -31.5 22.0 156.2 11.8 352 23 B A H 3X S+ 0 0 5 -4,-1.7 4,-2.9 -5,-0.3 -1,-0.2 0.830 100.9 56.1 -68.1 -29.9 25.7 156.4 12.6 353 24 B K H < S+ 0 0 34 -4,-1.8 3,-0.6 -5,-0.2 -2,-0.2 0.928 110.6 46.6 -69.5 -45.3 25.2 153.4 21.8 359 30 B F H 3< S+ 0 0 60 -4,-2.4 2,-1.6 1,-0.3 -2,-0.2 0.906 100.8 67.6 -62.9 -43.0 29.0 152.9 22.0 360 31 B M T 3< 0 0 130 -4,-2.7 -1,-0.3 -5,-0.2 -2,-0.1 -0.022 360.0 360.0 -71.7 36.3 29.5 155.9 24.2 361 32 B M < 0 0 194 -2,-1.6 -3,-0.0 -3,-0.6 -4,-0.0 -0.709 360.0 360.0-124.1 360.0 27.7 154.2 27.0