==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=27-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE (SERINE PROTEASE) 13-SEP-95 1DST . COMPND 2 MOLECULE: FACTOR D; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.V.L.NARAYANA,J.E.VOLANAKIS . 228 1 4 4 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 10629.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 143 62.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 4 1.8 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 71 31.1 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 1.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 21 9.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 23 10.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 14 6.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 2 2 5 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A I > 0 0 2 0, 0.0 3,-0.6 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 116.3 -14.5 21.9 73.5 2 17 A L B 3 +A 177 0A 24 175,-2.1 175,-1.9 1,-0.2 130,-0.1 -0.688 360.0 1.3 -84.4 132.3 -18.1 20.9 72.7 3 18 A G T 3 S+ 0 0 39 128,-0.7 -1,-0.2 -2,-0.4 129,-0.1 0.566 101.4 115.5 71.6 15.2 -20.5 20.9 75.6 4 19 A G < - 0 0 32 -3,-0.6 2,-0.3 173,-0.1 140,-0.2 0.049 55.3-122.9 -96.0-155.1 -18.2 22.0 78.4 5 20 A R E -B 143 0B 151 138,-2.0 138,-1.9 -3,-0.1 2,-0.3 -0.877 39.6 -71.8-144.6 170.5 -18.0 25.0 80.6 6 21 A E E -B 142 0B 117 -2,-0.3 136,-0.3 136,-0.2 135,-0.1 -0.538 51.1-127.3 -69.6 130.0 -15.4 27.7 81.4 7 22 A A - 0 0 4 134,-3.1 2,-0.4 -2,-0.3 -1,-0.1 -0.316 30.4 -95.8 -72.7 162.3 -12.5 26.4 83.5 8 23 A E > - 0 0 101 1,-0.1 3,-2.3 134,-0.0 4,-0.4 -0.703 56.9 -88.5 -80.7 131.1 -11.5 28.2 86.7 9 24 A A T 3 S- 0 0 61 -2,-0.4 -1,-0.1 1,-0.3 49,-0.1 -0.130 101.3 -15.0 -46.7 116.1 -8.7 30.6 86.0 10 25 A H T 3 S+ 0 0 53 47,-0.2 -1,-0.3 2,-0.1 48,-0.1 0.659 93.7 125.6 62.2 21.3 -5.3 29.0 86.3 11 26 A A S < S+ 0 0 60 -3,-2.3 -2,-0.1 1,-0.3 -1,-0.1 0.629 74.9 49.8 -80.5 -16.2 -6.7 25.9 88.1 12 27 A R S > S+ 0 0 30 -4,-0.4 3,-2.0 1,-0.1 -1,-0.3 -0.672 71.6 174.7-120.2 76.1 -5.0 23.7 85.5 13 28 A P T 3 S+ 0 0 27 0, 0.0 93,-0.9 0, 0.0 43,-0.4 0.572 70.3 66.8 -59.8 -13.6 -1.5 25.2 85.5 14 29 A Y T 3 S+ 0 0 24 91,-0.2 16,-2.5 93,-0.1 2,-0.3 0.466 74.5 116.2 -85.0 -8.0 -0.1 22.6 83.1 15 30 A M E < -J 29 0C 5 -3,-2.0 41,-0.4 14,-0.2 42,-0.4 -0.485 43.7-175.3 -70.5 127.8 -2.3 23.9 80.2 16 31 A A E -J 28 0C 0 12,-2.1 12,-1.1 -2,-0.3 2,-0.5 -0.897 20.8-143.8-123.8 151.7 -0.4 25.3 77.2 17 32 A S E -JK 27 54C 0 37,-2.1 37,-2.8 -2,-0.3 2,-0.7 -0.984 12.7-151.3-115.1 119.3 -1.5 27.0 74.1 18 33 A V E -JK 26 53C 3 8,-3.4 7,-3.0 -2,-0.5 8,-2.2 -0.862 25.3-161.1 -91.7 116.2 0.6 26.2 71.1 19 34 A Q E -JK 24 52C 16 33,-3.2 33,-2.3 -2,-0.7 2,-0.6 -0.831 21.8-154.2-110.4 145.2 0.4 29.3 68.9 20 35 A L E > S-JK 23 51C 35 3,-2.9 3,-1.7 -2,-0.4 31,-0.2 -0.926 85.1 -27.9-116.1 104.3 1.0 30.0 65.2 21 36 A N T 3 S- 0 0 114 29,-2.5 -1,-0.2 -2,-0.6 30,-0.1 0.948 128.0 -46.6 55.2 49.2 1.9 33.6 64.6 22 38 A G T 3 S+ 0 0 50 28,-0.3 2,-0.3 1,-0.2 -1,-0.3 0.167 117.0 108.3 84.1 -20.8 -0.1 34.7 67.6 23 39 A A E < S-J 20 0C 56 -3,-1.7 -3,-2.9 1,-0.1 2,-0.3 -0.687 79.6-107.0 -92.4 141.3 -3.2 32.6 66.9 24 40 A H E +J 19 0C 28 -2,-0.3 -5,-0.3 -5,-0.2 3,-0.1 -0.570 44.1 168.9 -65.1 128.7 -3.9 29.6 69.0 25 41 A L E - 0 0 26 -7,-3.0 2,-0.3 1,-0.4 -6,-0.2 0.761 56.6 -10.0-108.8 -49.5 -3.2 26.5 66.9 26 42 A a E -J 18 0C 3 -8,-2.2 -8,-3.4 156,-0.1 -1,-0.4 -0.946 65.1-105.0-150.7 163.3 -3.3 23.6 69.3 27 43 A G E -J 17 0C 0 156,-2.7 12,-0.4 -2,-0.3 2,-0.3 -0.340 37.3-177.0 -81.8 172.5 -3.4 22.6 73.0 28 44 A G E -J 16 0C 0 -12,-1.1 -12,-2.1 10,-0.1 2,-0.4 -0.959 20.6-129.7-164.2 165.5 -0.4 21.3 74.8 29 45 A V E -JL 15 37C 0 8,-2.8 8,-3.2 -2,-0.3 2,-0.7 -0.988 18.4-131.3-132.0 123.8 0.7 20.0 78.2 30 46 A L E + L 0 36C 0 -16,-2.5 78,-1.9 -2,-0.4 6,-0.2 -0.645 33.6 167.1 -73.5 113.3 3.7 21.2 80.3 31 47 A V E + 0 0 13 4,-2.1 2,-0.3 -2,-0.7 -1,-0.2 0.464 64.8 3.6-106.1 -8.0 5.5 17.9 81.2 32 48 A A E > S- L 0 35C 25 3,-1.3 3,-0.9 -3,-0.1 -1,-0.3 -0.964 89.0 -83.2-165.1 171.6 8.7 19.4 82.4 33 49 A E T 3 S+ 0 0 87 -2,-0.3 66,-3.3 1,-0.3 64,-0.1 0.820 128.4 19.4 -54.0 -36.7 10.4 22.8 83.0 34 50 A Q T 3 S+ 0 0 43 64,-0.2 61,-2.2 62,-0.1 2,-0.4 0.257 111.6 84.7-122.7 17.0 11.4 23.1 79.4 35 51 A W E < -LM 32 94C 30 -3,-0.9 -4,-2.1 59,-0.2 -3,-1.3 -0.966 46.2-169.8-132.4 134.6 9.1 20.7 77.5 36 52 A V E -LM 30 93C 0 57,-3.1 57,-3.1 -2,-0.4 2,-0.4 -0.979 14.3-150.0-119.7 123.4 5.6 20.9 76.2 37 53 A L E +LM 29 92C 0 -8,-3.2 -8,-2.8 -2,-0.5 2,-0.2 -0.775 34.8 137.7 -93.5 135.7 3.7 17.7 74.9 38 54 A S E - M 0 91C 0 53,-2.4 53,-2.7 -2,-0.4 2,-0.4 -0.758 54.3 -63.6-154.7-164.8 1.2 18.1 72.1 39 55 A A > - 0 0 0 -12,-0.4 3,-1.1 51,-0.3 4,-0.3 -0.811 31.2-137.6-103.9 138.1 0.1 16.4 68.9 40 56 A A T >> S+ 0 0 2 -2,-0.4 3,-2.1 1,-0.2 4,-0.6 0.867 99.0 65.0 -56.6 -44.0 2.4 15.9 65.8 41 57 A H H >> S+ 0 0 3 1,-0.3 4,-1.2 2,-0.2 3,-0.6 0.722 86.2 74.5 -56.4 -20.9 -0.2 16.8 63.2 42 58 A a H <> S+ 0 0 4 -3,-1.1 4,-0.6 1,-0.2 -1,-0.3 0.860 92.1 55.4 -60.8 -33.8 -0.3 20.3 64.6 43 59 A L H X4 S+ 0 0 57 -3,-2.1 3,-0.5 -4,-0.3 -1,-0.2 0.774 98.2 61.6 -68.5 -29.0 3.1 20.9 62.9 44 60 A E H << S+ 0 0 72 -3,-0.6 3,-0.3 -4,-0.6 -1,-0.2 0.878 100.0 54.9 -63.9 -38.1 1.6 19.9 59.5 45 61 A D H 3< S+ 0 0 65 -4,-1.2 2,-0.8 -3,-0.3 -1,-0.2 0.742 100.3 64.4 -67.9 -22.3 -0.8 22.8 59.8 46 61AA A << + 0 0 17 -4,-0.6 -1,-0.2 -3,-0.5 5,-0.1 -0.579 59.8 158.2-104.1 72.6 2.1 25.2 60.3 47 61BA A S S+ 0 0 80 -2,-0.8 -1,-0.2 -3,-0.3 -2,-0.1 0.733 79.4 1.5 -67.7 -30.3 4.0 25.0 57.0 48 61CA D S S+ 0 0 163 2,-0.0 -1,-0.2 0, 0.0 2,-0.1 0.323 106.7 103.7-140.7 7.8 6.0 28.3 57.0 49 62 A G S S- 0 0 35 1,-0.1 2,-0.6 -29,-0.0 -3,-0.1 -0.311 71.2 -98.7 -98.0 177.3 5.1 30.0 60.3 50 63 A K - 0 0 106 -2,-0.1 -29,-2.5 21,-0.0 2,-0.4 -0.838 33.6-157.9 -95.6 115.2 6.5 30.8 63.8 51 64 A V E +K 20 0C 27 -2,-0.6 21,-0.9 -31,-0.2 2,-0.3 -0.780 20.9 162.5 -94.6 132.2 5.3 28.4 66.5 52 65 A Q E -KN 19 71C 29 -33,-2.3 -33,-3.2 -2,-0.4 2,-0.4 -0.901 29.5-127.4-140.2 164.3 5.5 29.6 70.1 53 66 A V E -KN 18 70C 0 17,-2.3 17,-2.3 -2,-0.3 2,-0.5 -0.985 9.6-149.3-128.5 129.7 3.8 28.4 73.3 54 67 A L E -KN 17 69C 13 -37,-2.8 -37,-2.1 -2,-0.4 2,-0.2 -0.870 19.7-176.7 -95.8 124.7 1.8 30.5 75.7 55 68 A L E + N 0 68C 1 13,-2.7 13,-1.8 -2,-0.5 -39,-0.1 -0.743 58.2 33.7-115.8 164.6 1.8 29.4 79.4 56 69 A G S S+ 0 0 2 -41,-0.4 10,-0.4 -43,-0.4 2,-0.2 0.612 88.0 141.0 66.2 18.5 0.1 30.7 82.5 57 70 A A + 0 0 9 -42,-0.4 -47,-0.2 -3,-0.2 -1,-0.2 -0.587 32.5 157.9-101.1 152.6 -3.0 31.7 80.6 58 71 A H S S+ 0 0 13 1,-0.6 83,-1.2 -2,-0.2 2,-0.4 0.500 82.4 40.0-121.4 -65.4 -6.8 31.6 81.0 59 72 A S B S-P 140 0D 0 81,-0.2 -1,-0.6 1,-0.1 81,-0.3 -0.722 72.9-147.7 -87.3 133.0 -8.0 34.3 78.6 60 73 A L S S+ 0 0 47 79,-3.1 -1,-0.1 -2,-0.4 80,-0.1 0.728 95.2 29.4 -73.0 -22.7 -6.1 34.2 75.3 61 74 A S S S+ 0 0 90 78,-0.2 -1,-0.1 2,-0.1 79,-0.1 0.753 99.0 86.0-109.2 -30.5 -6.4 38.0 74.9 62 75 A Q S S- 0 0 111 77,-0.1 2,-0.2 1,-0.1 -4,-0.2 -0.433 82.3-109.1 -76.5 145.1 -6.6 39.6 78.3 63 76 A P - 0 0 123 0, 0.0 -1,-0.1 0, 0.0 -2,-0.1 -0.537 42.0-178.4 -71.9 137.6 -3.4 40.5 80.2 64 77 A E > - 0 0 30 -2,-0.2 3,-1.2 3,-0.0 -7,-0.0 -0.997 36.4-119.9-139.4 143.5 -2.8 38.2 83.2 65 78 A P T 3 S+ 0 0 144 0, 0.0 -8,-0.1 0, 0.0 -1,-0.0 0.667 111.3 41.6 -52.6 -26.6 -0.1 38.1 85.8 66 79 A S T 3 S+ 0 0 22 -10,-0.4 -9,-0.2 38,-0.0 2,-0.1 0.529 82.6 117.8-104.0 -5.9 1.1 34.6 84.9 67 80 A K < + 0 0 44 -3,-1.2 2,-0.3 -11,-0.2 -11,-0.2 -0.396 33.4 168.6 -66.4 134.5 1.0 34.7 81.1 68 81 A R E -N 55 0C 113 -13,-1.8 -13,-2.7 -2,-0.1 2,-0.4 -0.970 22.9-147.4-148.7 128.8 4.4 34.2 79.5 69 82 A L E -N 54 0C 77 -2,-0.3 2,-0.3 -15,-0.2 -15,-0.2 -0.846 18.9-169.2 -99.0 135.2 5.0 33.6 75.8 70 83 A Y E -N 53 0C 9 -17,-2.3 -17,-2.3 -2,-0.4 2,-0.2 -0.931 18.8-128.5-127.4 151.9 8.0 31.4 74.8 71 84 A D E -N 52 0C 66 -2,-0.3 25,-3.0 -19,-0.2 2,-0.6 -0.613 30.5-116.2 -90.8 155.5 9.8 30.5 71.5 72 85 A V E -O 95 0C 36 -21,-0.9 23,-0.3 23,-0.2 3,-0.1 -0.867 23.6-171.9-100.4 120.7 10.3 26.9 70.6 73 86 A L E S+ 0 0 96 21,-2.1 2,-0.3 -2,-0.6 22,-0.2 0.849 73.6 4.9 -73.8 -43.5 13.9 25.8 70.4 74 87 A R E -O 94 0C 168 20,-1.0 20,-2.8 2,-0.0 2,-0.5 -0.988 59.6-151.0-149.0 138.7 13.3 22.3 69.0 75 88 A A E -O 93 0C 45 -2,-0.3 18,-0.2 18,-0.2 -3,-0.0 -0.964 14.2-171.7-113.1 121.6 10.2 20.5 67.8 76 89 A V E -O 92 0C 40 16,-3.4 16,-2.3 -2,-0.5 2,-0.1 -0.814 3.0-172.4-118.9 89.5 10.5 16.7 68.2 77 90 A P E -O 91 0C 56 0, 0.0 14,-0.2 0, 0.0 12,-0.1 -0.414 46.6 -80.7 -74.5 155.2 7.6 14.8 66.5 78 91 A H > - 0 0 10 12,-2.7 3,-1.9 10,-0.4 13,-0.0 -0.355 41.7-126.0 -56.8 133.9 7.3 11.0 67.2 79 92 A P T 3 S+ 0 0 92 0, 0.0 -1,-0.1 0, 0.0 9,-0.0 0.758 106.6 47.6 -52.7 -31.5 9.9 9.3 64.8 80 93 A D T 3 S+ 0 0 93 8,-0.1 2,-0.3 2,-0.1 -2,-0.1 0.309 79.9 127.5 -98.7 11.7 7.2 6.9 63.3 81 94 A Y < - 0 0 26 -3,-1.9 7,-0.1 7,-0.2 5,-0.0 -0.530 39.3-167.0 -75.8 128.7 4.5 9.6 62.7 82 95 A Q - 0 0 121 5,-0.4 5,-0.1 -2,-0.3 -2,-0.1 -0.955 27.5-112.5-116.9 114.6 3.3 9.5 59.0 83 96 A P S S+ 0 0 82 0, 0.0 3,-0.1 0, 0.0 -42,-0.0 -0.265 102.1 25.3 -53.8 135.1 1.2 12.5 57.8 84 97 A D S S+ 0 0 151 1,-0.4 2,-0.3 2,-0.0 0, 0.0 0.945 104.1 95.3 64.5 63.2 -2.4 11.5 57.2 85 98 A T - 0 0 57 2,-0.1 -1,-0.4 -3,-0.0 -4,-0.0 -0.847 68.9-138.4-163.7 156.4 -2.4 8.6 59.5 86 99 A I > + 0 0 75 -2,-0.3 3,-0.7 -3,-0.1 113,-0.1 0.714 67.7 90.3-104.9 -22.5 -3.6 8.7 63.1 87 100 A D T 3 S+ 0 0 52 1,-0.2 -5,-0.4 -5,-0.1 3,-0.1 -0.347 85.2 23.3 -78.4 160.8 -1.0 6.7 65.2 88 101 A H T 3 S+ 0 0 25 1,-0.2 2,-2.8 -7,-0.1 -10,-0.4 0.639 73.3 161.4 56.0 35.7 2.1 8.1 66.9 89 102 A D < + 0 0 0 -3,-0.7 2,-0.4 -50,-0.1 -1,-0.2 -0.281 26.0 123.2 -82.7 62.5 0.5 11.5 66.9 90 103 A L - 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