==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=14-APR-2010 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 19-JAN-07 2E88 . COMPND 2 MOLECULE: HEAT SHOCK 70KDA PROTEIN 1A; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR M.SHIDA,R.ISHII,T.TAKAGI,S.KISHISHITA,M.SHIROUZU,S.YOKOYAMA, . 381 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 17083.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 283 74.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 21 5.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 60 15.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 6 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 25 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 46 12.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 118 31.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 5 1.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 1 2 1 0 1 1 0 1 1 0 0 0 0 0 3 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 0 2 1 2 2 0 2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 2 2 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A K 0 0 246 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -56.0 46.2 30.7 18.5 2 4 A A - 0 0 27 1,-0.1 2,-0.1 134,-0.1 135,-0.1 -0.313 360.0-120.6 -64.5 136.8 43.2 28.8 19.8 3 5 A A - 0 0 8 -2,-0.1 136,-0.3 1,-0.1 135,-0.3 -0.396 21.2-129.2 -74.6 151.2 40.2 27.9 17.5 4 6 A A - 0 0 2 15,-0.2 15,-0.6 368,-0.1 2,-0.3 -0.674 25.9-131.6 -94.5 155.5 36.7 29.2 18.4 5 7 A I E -Ab 18 140A 0 134,-2.3 136,-2.3 -2,-0.3 2,-0.5 -0.746 1.4-136.4-111.3 157.6 33.9 26.6 18.4 6 8 A G E -Ab 17 141A 0 11,-2.5 11,-2.4 -2,-0.3 2,-0.5 -0.952 24.0-166.4-108.5 127.9 30.4 26.5 16.9 7 9 A I E -Ab 16 142A 0 134,-2.8 136,-1.9 -2,-0.5 2,-0.9 -0.965 19.1-158.5-126.4 123.4 27.7 25.2 19.2 8 10 A D E -Ab 15 143A 25 7,-2.6 7,-1.7 -2,-0.5 2,-1.4 -0.853 16.3-161.5 -89.6 105.2 24.2 24.2 18.3 9 11 A L - 0 0 7 -2,-0.9 5,-0.2 134,-0.5 2,-0.1 -0.741 22.6-171.3 -93.1 88.7 22.5 24.6 21.8 10 12 A G - 0 0 9 -2,-1.4 59,-0.1 3,-0.3 57,-0.1 -0.448 35.3-121.3 -87.9 159.9 19.5 22.4 21.0 11 13 A T S S+ 0 0 27 -2,-0.1 56,-0.7 1,-0.1 58,-0.3 0.928 111.8 10.1 -61.4 -46.1 16.3 21.8 22.9 12 14 A T S S+ 0 0 30 1,-0.3 26,-2.7 54,-0.1 2,-0.3 0.825 137.9 17.0-102.2 -42.2 16.9 18.0 23.1 13 15 A Y E -E 37 0B 44 24,-0.3 -1,-0.3 25,-0.1 -3,-0.3 -0.962 62.3-153.2-131.8 153.5 20.5 17.6 21.9 14 16 A S E -E 36 0B 0 22,-3.3 22,-2.8 -2,-0.3 2,-0.3 -0.807 8.3-163.2-120.7 162.4 23.5 19.9 21.4 15 17 A C E -A 8 0A 1 -7,-1.7 -7,-2.6 -2,-0.3 2,-0.4 -0.995 3.1-156.4-147.9 143.2 26.4 19.6 19.0 16 18 A V E +A 7 0A 0 11,-0.4 11,-2.5 18,-0.4 2,-0.3 -0.987 12.9 176.1-128.8 137.0 29.8 21.2 18.8 17 19 A G E -AC 6 26A 0 -11,-2.4 -11,-2.5 -2,-0.4 2,-0.3 -0.882 9.1-162.1-131.2 163.7 32.1 21.8 15.8 18 20 A V E -AC 5 25A 0 7,-2.3 7,-2.5 -2,-0.3 2,-0.6 -0.995 18.4-132.7-148.9 141.7 35.4 23.5 15.2 19 21 A F E + C 0 24A 53 -15,-0.6 2,-0.3 353,-0.4 5,-0.2 -0.872 49.8 133.7 -94.9 119.8 37.2 24.7 12.1 20 22 A Q E > + C 0 23A 32 3,-2.4 3,-1.4 -2,-0.6 -2,-0.1 -0.970 54.3 27.6-160.9 151.4 40.8 23.5 12.1 21 23 A H T 3 S- 0 0 155 -2,-0.3 3,-0.1 1,-0.3 -1,-0.1 0.867 130.7 -60.2 62.0 34.7 43.3 21.9 9.7 22 24 A G T 3 S+ 0 0 64 1,-0.1 2,-0.3 -3,-0.0 -1,-0.3 0.500 121.2 68.2 73.1 6.4 41.4 23.5 6.8 23 25 A K E < S-C 20 0A 113 -3,-1.4 -3,-2.4 -5,-0.1 2,-0.4 -0.958 82.8-100.9-148.6 165.0 38.1 21.8 7.5 24 26 A V E -C 19 0A 18 -2,-0.3 2,-0.4 -5,-0.2 -5,-0.2 -0.750 34.5-168.3 -89.5 137.9 35.1 21.7 9.9 25 27 A E E -C 18 0A 40 -7,-2.5 -7,-2.3 -2,-0.4 2,-0.5 -0.996 14.9-143.6-126.6 128.2 35.2 18.8 12.3 26 28 A I E -C 17 0A 10 -2,-0.4 2,-0.4 -9,-0.2 -9,-0.3 -0.812 29.0-128.1 -89.1 132.1 32.1 17.9 14.4 27 29 A I - 0 0 3 -11,-2.5 -11,-0.4 -2,-0.5 2,-0.2 -0.699 11.2-142.9 -94.3 127.4 33.4 16.6 17.8 28 30 A A - 0 0 45 -2,-0.4 6,-0.3 1,-0.1 104,-0.1 -0.542 20.4-127.4 -80.3 148.2 32.4 13.4 19.4 29 31 A N > - 0 0 8 4,-3.0 3,-2.5 -2,-0.2 -1,-0.1 -0.205 40.7 -80.4 -85.2-175.3 31.9 13.3 23.2 30 32 A D T 3 S+ 0 0 117 1,-0.3 -1,-0.1 2,-0.2 -2,-0.0 0.593 132.1 53.4 -65.0 -10.5 33.6 10.7 25.5 31 33 A Q T 3 S- 0 0 120 2,-0.2 -1,-0.3 0, 0.0 -2,-0.0 0.299 123.4-105.8-100.7 4.3 31.0 8.1 24.7 32 34 A G S < S+ 0 0 52 -3,-2.5 2,-0.4 1,-0.3 -2,-0.2 0.569 72.9 146.1 83.8 9.2 31.8 8.6 21.0 33 35 A N - 0 0 68 1,-0.1 -4,-3.0 -5,-0.1 -1,-0.3 -0.680 44.1-154.1 -89.1 133.4 28.5 10.5 20.4 34 36 A R S S+ 0 0 112 -2,-0.4 -18,-0.4 -6,-0.3 2,-0.3 0.561 85.8 38.3 -77.5 -13.3 28.4 13.3 17.8 35 37 A T S S- 0 0 15 -20,-0.1 -20,-0.2 -9,-0.1 -6,-0.2 -0.951 77.1-147.8-133.5 152.5 25.5 15.0 19.6 36 38 A T E -E 14 0B 2 -22,-2.8 -22,-3.3 -2,-0.3 14,-0.1 -0.973 24.3-106.4-126.3 137.3 25.0 15.3 23.4 37 39 A P E -E 13 0B 0 0, 0.0 2,-2.0 0, 0.0 -24,-0.3 -0.372 24.7-129.3 -61.5 136.7 21.7 15.4 25.3 38 40 A S + 0 0 12 -26,-2.7 30,-0.4 11,-0.1 29,-0.4 -0.441 67.2 130.5 -85.1 62.8 20.8 18.8 26.7 39 41 A Y - 0 0 33 -2,-2.0 11,-2.7 27,-0.1 2,-0.4 -0.930 38.9-174.4-122.0 145.1 20.3 17.3 30.1 40 42 A V E -FG 49 65C 0 25,-2.2 25,-3.1 -2,-0.4 2,-0.4 -0.993 10.1-169.0-138.0 125.0 21.5 18.1 33.6 41 43 A A E -FG 48 64C 0 7,-2.9 7,-2.7 -2,-0.4 2,-0.5 -0.912 8.9-154.1-120.0 145.5 20.8 15.8 36.6 42 44 A F E +F 47 0C 0 21,-2.4 5,-0.2 -2,-0.4 62,-0.2 -0.967 20.5 173.1-118.0 130.6 21.3 16.5 40.3 43 45 A T - 0 0 29 3,-2.5 63,-2.5 -2,-0.5 64,-0.1 -0.600 51.8 -83.5-123.9-174.1 21.9 13.6 42.7 44 46 A D S S+ 0 0 130 61,-0.2 61,-0.1 -2,-0.2 3,-0.1 0.753 126.6 15.1 -64.6 -19.9 22.7 13.1 46.3 45 47 A T S S+ 0 0 101 1,-0.2 2,-0.3 61,-0.1 -1,-0.2 0.578 121.0 24.9-132.7 -12.6 26.4 13.4 45.3 46 48 A E - 0 0 104 2,-0.0 -3,-2.5 0, 0.0 2,-0.5 -0.955 56.8-119.9-152.3 172.8 26.9 14.9 41.9 47 49 A R E -F 42 0C 117 -2,-0.3 2,-0.4 -5,-0.2 -5,-0.2 -0.976 33.3-164.5-114.4 118.4 25.9 17.0 39.0 48 50 A L E -F 41 0C 31 -7,-2.7 -7,-2.9 -2,-0.5 2,-0.4 -0.854 4.8-170.6-108.4 141.1 25.7 15.0 35.7 49 51 A I E > -F 40 0C 32 -2,-0.4 3,-0.8 -9,-0.2 2,-0.3 -0.983 48.8 -11.8-133.9 141.7 25.5 16.6 32.3 50 52 A G T 3> S+ 0 0 0 -11,-2.7 4,-2.6 -2,-0.4 3,-0.5 -0.556 126.5 4.5 80.4-135.3 24.8 15.1 28.8 51 53 A D H 3> S+ 0 0 20 -2,-0.3 4,-2.6 1,-0.2 -1,-0.2 0.878 131.1 53.9 -56.4 -42.3 24.8 11.4 28.4 52 54 A A H <> S+ 0 0 45 -3,-0.8 4,-0.6 1,-0.2 -1,-0.2 0.853 112.1 45.7 -62.8 -34.7 25.3 10.6 32.0 53 55 A A H >4 S+ 0 0 0 -3,-0.5 3,-1.0 -14,-0.3 -2,-0.2 0.940 113.7 46.5 -73.6 -47.7 22.3 12.7 32.9 54 56 A K H >< S+ 0 0 40 -4,-2.6 3,-1.5 1,-0.2 4,-0.3 0.886 106.1 63.1 -62.0 -34.4 20.0 11.4 30.2 55 57 A N H 3< S+ 0 0 113 -4,-2.6 -1,-0.2 -5,-0.3 3,-0.2 0.733 109.2 37.2 -64.4 -24.0 21.1 7.9 31.2 56 58 A Q T XX S+ 0 0 24 -3,-1.0 4,-1.0 -4,-0.6 3,-0.6 0.123 79.4 112.3-114.9 23.6 19.6 8.1 34.7 57 59 A V T <4 S+ 0 0 32 -3,-1.5 3,-0.2 1,-0.2 7,-0.1 0.838 76.2 55.9 -64.3 -30.2 16.5 10.1 33.9 58 60 A A T 34 S+ 0 0 27 -4,-0.3 -1,-0.2 1,-0.2 -2,-0.1 0.782 109.6 45.5 -72.6 -26.1 14.3 7.1 34.7 59 61 A L T <4 S+ 0 0 123 -3,-0.6 -1,-0.2 1,-0.2 -2,-0.2 0.634 125.9 28.6 -90.2 -12.7 15.8 6.7 38.1 60 62 A N >< + 0 0 24 -4,-1.0 3,-0.8 -3,-0.2 4,-0.4 -0.307 64.4 155.1-148.2 57.0 15.6 10.4 39.0 61 63 A P G > S+ 0 0 31 0, 0.0 3,-0.6 0, 0.0 -1,-0.1 0.822 74.6 53.7 -57.1 -36.1 12.7 12.2 37.1 62 64 A Q G 3 S+ 0 0 140 1,-0.2 29,-0.5 28,-0.1 40,-0.0 0.796 116.7 36.0 -73.0 -24.9 12.3 15.0 39.6 63 65 A N G < S+ 0 0 25 -3,-0.8 -21,-2.4 40,-0.1 2,-0.7 0.192 92.9 94.3-114.3 15.6 15.9 16.1 39.6 64 66 A T E < -G 41 0C 0 -3,-0.6 2,-0.3 -4,-0.4 -23,-0.3 -0.935 63.1-159.2-110.3 108.9 16.8 15.5 35.9 65 67 A V E +G 40 0C 1 -25,-3.1 -25,-2.2 -2,-0.7 2,-0.3 -0.696 22.8 150.2 -95.2 139.2 16.3 18.8 34.1 66 68 A F + 0 0 34 -2,-0.3 -27,-0.1 -27,-0.2 -54,-0.1 -0.884 50.1 50.7-150.3 177.3 15.8 19.1 30.3 67 69 A D > + 0 0 18 -56,-0.7 3,-2.3 -29,-0.4 4,-0.5 0.700 57.4 147.0 60.6 21.0 14.0 21.4 27.9 68 70 A A G >> + 0 0 9 -30,-0.4 4,-1.9 1,-0.3 3,-1.3 0.787 63.6 69.4 -59.4 -23.5 15.6 24.4 29.6 69 71 A K G 34 S+ 0 0 21 1,-0.3 -1,-0.3 -58,-0.3 -58,-0.1 0.718 90.9 60.2 -66.0 -19.1 15.5 26.0 26.1 70 72 A R G <4 S+ 0 0 62 -3,-2.3 -1,-0.3 1,-0.2 -2,-0.2 0.684 113.2 36.8 -80.9 -17.4 11.8 26.2 26.4 71 73 A L T X4 S+ 0 0 0 -3,-1.3 3,-2.0 -4,-0.5 -2,-0.2 0.666 87.2 119.2-103.9 -23.1 12.2 28.4 29.5 72 74 A I T 3< S- 0 0 2 -4,-1.9 3,-0.1 1,-0.3 84,-0.1 -0.161 86.8 -1.1 -57.2 131.1 15.2 30.5 28.6 73 75 A G T 3 S+ 0 0 14 1,-0.2 -1,-0.3 79,-0.1 2,-0.2 0.568 106.5 118.7 70.7 8.4 14.7 34.2 28.4 74 76 A R < - 0 0 54 -3,-2.0 2,-0.2 77,-0.1 -1,-0.2 -0.656 63.8-114.9-105.6 165.5 11.0 33.9 29.3 75 77 A K > - 0 0 87 -2,-0.2 3,-1.8 23,-0.2 6,-0.3 -0.650 25.0-119.2 -95.0 151.7 8.9 35.2 32.2 76 78 A F T 3 S+ 0 0 37 21,-3.3 6,-0.1 1,-0.3 22,-0.1 0.890 115.3 51.6 -56.5 -41.8 7.2 32.9 34.7 77 79 A G T 3 S+ 0 0 46 20,-0.3 -1,-0.3 4,-0.1 21,-0.1 0.490 78.8 126.8 -75.8 -2.3 3.8 34.2 33.7 78 80 A D <> - 0 0 37 -3,-1.8 4,-2.9 19,-0.2 5,-0.2 -0.336 65.7-132.7 -56.1 130.2 4.5 33.6 30.0 79 81 A P H > S+ 0 0 101 0, 0.0 4,-2.0 0, 0.0 -1,-0.2 0.783 107.0 55.9 -58.2 -27.6 1.5 31.4 28.8 80 82 A V H > S+ 0 0 56 2,-0.2 4,-2.7 3,-0.2 5,-0.2 0.926 110.5 43.7 -69.7 -44.4 4.0 29.1 27.1 81 83 A V H > S+ 0 0 0 -6,-0.3 4,-2.2 2,-0.2 -1,-0.1 0.950 113.0 51.4 -65.6 -49.1 5.8 28.5 30.4 82 84 A Q H X S+ 0 0 87 -4,-2.9 4,-0.5 1,-0.2 -1,-0.2 0.892 114.9 43.8 -55.6 -41.0 2.6 28.1 32.3 83 85 A S H >< S+ 0 0 67 -4,-2.0 3,-0.8 -5,-0.2 4,-0.3 0.905 111.8 50.5 -72.8 -42.5 1.4 25.5 29.8 84 86 A D H >X S+ 0 0 36 -4,-2.7 3,-1.9 1,-0.2 4,-0.5 0.834 97.5 72.3 -63.7 -33.0 4.7 23.6 29.5 85 87 A M H >< S+ 0 0 41 -4,-2.2 3,-0.8 1,-0.3 -1,-0.2 0.766 85.6 61.5 -55.5 -33.6 5.0 23.2 33.2 86 88 A K T << S+ 0 0 171 -3,-0.8 -1,-0.3 -4,-0.5 -2,-0.1 0.682 105.4 50.7 -70.8 -13.0 2.2 20.7 33.6 87 89 A H T <4 S+ 0 0 133 -3,-1.9 -1,-0.2 -4,-0.3 -2,-0.2 0.559 90.4 88.9-100.5 -9.3 4.2 18.3 31.4 88 90 A W << - 0 0 23 -3,-0.8 4,-0.1 -4,-0.5 -23,-0.0 -0.692 63.4-148.5 -92.1 142.8 7.6 18.4 33.2 89 91 A P S S+ 0 0 56 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.596 80.4 75.2 -82.2 -11.3 8.5 16.0 36.0 90 92 A F S S- 0 0 9 -26,-0.1 2,-0.3 -24,-0.1 -2,-0.1 -0.681 90.1-104.5 -99.6 157.7 10.7 18.6 37.6 91 93 A Q E -H 102 0D 111 11,-0.9 11,-2.7 -29,-0.5 2,-0.4 -0.582 26.5-167.0 -85.4 139.6 9.5 21.6 39.5 92 94 A V E -H 101 0D 4 -2,-0.3 2,-0.3 9,-0.2 9,-0.2 -0.991 13.4-171.2-122.3 131.3 9.6 25.2 38.1 93 95 A I E -H 100 0D 41 7,-3.0 7,-1.9 -2,-0.4 2,-0.5 -0.827 24.6-106.8-123.6 165.3 9.0 28.1 40.5 94 96 A N E +H 99 0D 87 -2,-0.3 2,-0.3 5,-0.2 -19,-0.0 -0.782 33.5 170.3 -95.1 126.0 8.5 31.8 40.3 95 97 A D E > S-H 98 0D 66 3,-2.4 3,-1.0 -2,-0.5 -19,-0.1 -0.797 79.6 -30.2-136.9 92.6 11.3 34.2 41.2 96 98 A G T 3 S- 0 0 69 -2,-0.3 -2,-0.0 1,-0.3 -20,-0.0 0.842 120.4 -56.0 67.8 33.4 10.6 37.8 40.3 97 99 A D T 3 S+ 0 0 71 1,-0.3 -21,-3.3 -22,-0.1 -20,-0.3 0.566 119.7 112.9 71.6 10.8 8.5 36.7 37.4 98 100 A K E < -H 95 0D 58 -3,-1.0 -3,-2.4 -23,-0.3 -1,-0.3 -0.933 68.9-124.4-109.2 135.4 11.6 34.7 36.1 99 101 A P E -H 94 0D 1 0, 0.0 2,-0.3 0, 0.0 -5,-0.2 -0.527 25.7-171.3 -80.4 149.8 11.2 30.9 36.2 100 102 A K E -H 93 0D 29 -7,-1.9 -7,-3.0 13,-0.2 2,-0.5 -0.989 23.5-126.3-136.5 141.4 13.7 28.7 38.1 101 103 A V E -HI 92 112D 0 11,-2.8 11,-2.3 -2,-0.3 2,-0.5 -0.796 27.4-153.4 -89.0 127.2 14.0 25.0 38.0 102 104 A Q E +HI 91 111D 73 -11,-2.7 -11,-0.9 -2,-0.5 2,-0.3 -0.899 24.4 155.9-107.9 130.2 13.9 23.6 41.6 103 105 A V E - I 0 110D 4 7,-3.0 7,-2.7 -2,-0.5 2,-0.5 -0.849 45.7-101.9-141.5 174.9 15.6 20.3 42.5 104 106 A S E + I 0 109D 59 -2,-0.3 2,-0.4 5,-0.2 5,-0.2 -0.908 42.9 173.6-100.8 127.8 17.1 18.3 45.3 105 107 A Y E > - I 0 108D 31 3,-3.0 3,-1.4 -2,-0.5 -61,-0.2 -0.962 65.8 -14.7-142.5 120.3 20.9 18.4 45.1 106 108 A K T 3 S- 0 0 111 -63,-2.5 -62,-0.2 -2,-0.4 -1,-0.1 0.893 130.6 -50.4 53.3 44.6 23.3 16.9 47.7 107 109 A G T 3 S+ 0 0 66 1,-0.2 2,-0.3 -64,-0.1 -1,-0.3 0.512 121.2 90.6 77.1 4.7 20.4 16.6 50.1 108 110 A E E < S-I 105 0D 112 -3,-1.4 -3,-3.0 -64,-0.0 2,-0.4 -0.949 79.1-103.6-135.4 156.8 19.1 20.2 49.8 109 111 A T E +I 104 0D 91 -2,-0.3 2,-0.3 -5,-0.2 -5,-0.2 -0.616 44.2 171.9 -76.1 127.1 16.7 22.2 47.7 110 112 A K E -I 103 0D 84 -7,-2.7 -7,-3.0 -2,-0.4 2,-0.4 -0.967 16.7-155.1-135.1 148.6 18.4 24.3 45.1 111 113 A A E -I 102 0D 32 -2,-0.3 2,-0.4 -9,-0.2 -9,-0.2 -0.971 7.0-166.1-128.3 146.7 16.9 26.4 42.2 112 114 A F E -I 101 0D 31 -11,-2.3 -11,-2.8 -2,-0.4 -2,-0.0 -0.987 21.1-123.0-134.2 138.1 18.5 27.4 39.0 113 115 A Y >> - 0 0 62 -2,-0.4 4,-1.9 -13,-0.2 3,-0.9 -0.367 37.4-107.7 -70.7 158.8 17.6 30.0 36.3 114 116 A P H 3> S+ 0 0 1 0, 0.0 4,-2.7 0, 0.0 5,-0.2 0.892 121.0 54.3 -57.1 -39.4 17.2 28.6 32.8 115 117 A E H 3> S+ 0 0 25 1,-0.2 4,-1.5 2,-0.2 47,-0.1 0.783 104.8 55.2 -66.3 -24.7 20.5 30.2 31.7 116 118 A E H <> S+ 0 0 63 -3,-0.9 4,-1.2 2,-0.2 -1,-0.2 0.936 109.6 45.8 -71.3 -45.2 22.3 28.5 34.5 117 119 A I H >X S+ 0 0 3 -4,-1.9 4,-1.5 1,-0.2 3,-0.8 0.946 114.9 46.7 -60.3 -49.0 21.0 25.1 33.4 118 120 A S H 3X S+ 0 0 8 -4,-2.7 4,-2.8 1,-0.3 -1,-0.2 0.825 105.6 61.1 -65.4 -27.6 21.9 25.8 29.8 119 121 A S H 3X S+ 0 0 8 -4,-1.5 4,-2.1 -5,-0.2 -1,-0.3 0.834 102.2 52.6 -66.3 -30.2 25.3 27.1 30.9 120 122 A M H - 0 0 5 0, 0.0 3,-2.1 0, 0.0 27,-0.0 -0.370 40.2-119.3 -64.9 147.4 15.9 29.7 16.5 146 148 A A T 3 S+ 0 0 19 1,-0.3 26,-0.1 26,-0.0 71,-0.1 0.768 113.4 58.2 -57.7 -26.1 15.2 32.5 14.1 147 149 A Y T 3 S+ 0 0 109 2,-0.0 -1,-0.3 0, 0.0 2,-0.1 0.389 75.9 118.5 -88.0 4.8 12.0 33.3 16.2 148 150 A F < - 0 0 15 -3,-2.1 2,-0.1 4,-0.1 -4,-0.1 -0.462 57.6-139.4 -69.4 142.0 13.9 33.9 19.4 149 151 A N > - 0 0 83 -2,-0.1 4,-2.3 1,-0.0 5,-0.2 -0.318 31.8 -86.8 -92.6-178.4 13.4 37.4 20.7 150 152 A D H > S+ 0 0 137 1,-0.2 4,-2.6 2,-0.2 5,-0.2 0.854 126.7 51.6 -58.1 -40.1 16.0 39.7 22.3 151 153 A S H > S+ 0 0 53 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.887 110.8 47.5 -66.2 -41.0 15.4 38.4 25.8 152 154 A Q H > S+ 0 0 7 2,-0.2 4,-1.7 1,-0.2 -2,-0.2 0.897 113.7 48.8 -66.8 -38.3 15.9 34.8 24.7 153 155 A R H X S+ 0 0 55 -4,-2.3 4,-2.6 2,-0.2 -2,-0.2 0.929 111.3 49.5 -66.0 -44.1 19.0 35.8 22.8 154 156 A Q H X S+ 0 0 105 -4,-2.6 4,-2.9 1,-0.2 -2,-0.2 0.934 111.4 48.0 -58.7 -48.9 20.4 37.6 25.8 155 157 A A H X S+ 0 0 8 -4,-2.3 4,-1.9 2,-0.2 -1,-0.2 0.819 110.9 51.5 -64.4 -32.1 19.8 34.7 28.1 156 158 A T H X S+ 0 0 6 -4,-1.7 4,-1.8 2,-0.2 -1,-0.2 0.930 111.2 47.3 -70.5 -43.6 21.4 32.3 25.7 157 159 A K H X S+ 0 0 87 -4,-2.6 4,-2.4 1,-0.2 -2,-0.2 0.928 110.1 53.7 -60.9 -42.1 24.5 34.6 25.4 158 160 A D H X S+ 0 0 57 -4,-2.9 4,-2.8 1,-0.2 -1,-0.2 0.898 104.4 54.9 -59.4 -40.2 24.5 34.8 29.2 159 161 A A H X S+ 0 0 0 -4,-1.9 4,-1.6 1,-0.2 -1,-0.2 0.888 109.1 48.7 -59.5 -39.5 24.5 31.0 29.4 160 162 A G H <>S+ 0 0 0 -4,-1.8 5,-2.5 2,-0.2 -2,-0.2 0.905 111.7 47.0 -69.4 -39.9 27.6 31.0 27.2 161 163 A V H ><5S+ 0 0 78 -4,-2.4 3,-2.0 1,-0.2 -2,-0.2 0.895 108.3 55.2 -70.0 -37.7 29.4 33.6 29.3 162 164 A I H 3<5S+ 0 0 107 -4,-2.8 -1,-0.2 1,-0.3 -2,-0.2 0.902 105.4 55.1 -58.7 -38.8 28.5 31.7 32.5 163 165 A A T 3<5S- 0 0 6 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.434 127.4-103.2 -72.8 -0.5 30.2 28.7 30.9 164 166 A G T < 5S+ 0 0 41 -3,-2.0 2,-0.4 1,-0.3 -3,-0.2 0.723 78.1 133.3 86.2 21.8 33.3 30.8 30.3 165 167 A L < - 0 0 3 -5,-2.5 2,-0.7 -6,-0.1 -1,-0.3 -0.895 56.0-136.5-110.4 135.2 32.9 31.5 26.7 166 168 A N E -d 139 0A 93 -28,-3.2 -26,-2.2 -2,-0.4 2,-1.1 -0.792 29.2-137.2 -80.4 121.7 33.2 34.9 24.9 167 169 A V E -d 140 0A 9 -2,-0.7 -26,-0.2 1,-0.2 3,-0.1 -0.726 20.8-172.7 -89.1 100.3 30.2 34.8 22.7 168 170 A L E - 0 0 47 -28,-2.1 2,-0.3 -2,-1.1 -27,-0.2 0.885 67.8 -24.2 -57.1 -42.1 31.4 36.1 19.3 169 171 A R E -d 141 0A 120 -29,-0.7 -27,-1.8 -3,-0.1 2,-0.5 -0.970 49.9-131.8-168.3 155.3 27.9 36.1 18.0 170 172 A I E -d 142 0A 39 -2,-0.3 2,-0.3 -29,-0.2 -27,-0.2 -0.986 37.3-178.6-112.9 118.8 24.5 34.5 18.4 171 173 A I E -d 143 0A 13 -29,-1.6 -27,-1.7 -2,-0.5 2,-0.1 -0.883 31.0 -93.6-122.4 157.4 23.2 33.5 14.9 172 174 A N E > -d 144 0A 27 -2,-0.3 4,-2.5 -29,-0.2 5,-0.2 -0.413 28.4-126.7 -68.6 141.2 20.0 31.9 13.7 173 175 A E H > S+ 0 0 13 -29,-2.9 4,-2.2 1,-0.2 5,-0.2 0.922 109.9 47.5 -54.1 -51.2 19.8 28.1 13.4 174 176 A P H > S+ 0 0 9 0, 0.0 4,-1.9 0, 0.0 -1,-0.2 0.872 111.4 52.6 -62.7 -30.2 18.6 28.1 9.7 175 177 A T H > S+ 0 0 14 2,-0.2 4,-2.5 1,-0.2 -2,-0.2 0.925 107.6 51.2 -66.3 -45.8 21.3 30.7 8.9 176 178 A A H X S+ 0 0 0 -4,-2.5 4,-2.1 1,-0.2 -1,-0.2 0.902 108.5 51.9 -57.5 -42.8 24.0 28.5 10.4 177 179 A A H X S+ 0 0 0 -4,-2.2 4,-1.3 2,-0.2 -1,-0.2 0.894 109.7 49.2 -63.9 -37.2 22.7 25.6 8.3 178 180 A A H <>S+ 0 0 0 -4,-1.9 5,-2.3 1,-0.2 3,-0.3 0.920 110.4 50.7 -67.0 -41.2 22.9 27.7 5.1 179 181 A I H ><5S+ 0 0 9 -4,-2.5 3,-2.0 1,-0.2 -1,-0.2 0.873 102.6 61.0 -62.3 -37.5 26.4 28.7 6.0 180 182 A A H 3<5S+ 0 0 11 -4,-2.1 -1,-0.2 1,-0.3 -2,-0.2 0.890 107.4 44.9 -57.6 -38.7 27.4 25.1 6.5 181 183 A Y T 3<5S- 0 0 34 -4,-1.3 -1,-0.3 -3,-0.3 -2,-0.2 0.258 116.1-116.5 -88.9 11.2 26.5 24.4 2.8 182 184 A G T X 5 + 0 0 16 -3,-2.0 3,-1.0 1,-0.1 -3,-0.2 0.766 67.0 144.3 60.6 32.5 28.4 27.6 1.7 183 185 A L T 3 < + 0 0 27 -5,-2.3 3,-0.3 1,-0.2 30,-0.2 0.550 62.6 58.7 -80.5 -6.3 25.2 29.2 0.4 184 186 A D T 3 S+ 0 0 39 -6,-0.3 -1,-0.2 1,-0.2 -5,-0.1 0.100 82.4 86.2-107.0 23.1 26.2 32.7 1.4 185 187 A R < + 0 0 203 -3,-1.0 -1,-0.2 27,-0.0 -2,-0.1 0.456 66.9 90.8-103.4 0.2 29.4 32.8 -0.6 186 188 A T S S- 0 0 83 -3,-0.3 3,-0.1 1,-0.2 2,-0.1 0.131 73.0-115.9 -75.6-161.6 28.0 34.0 -3.9 187 189 A G - 0 0 28 1,-0.3 25,-1.8 25,-0.1 26,-0.3 -0.056 59.1 -19.4-115.3-142.3 27.7 37.6 -5.0 188 190 A K S S+ 0 0 158 23,-0.2 -1,-0.3 24,-0.2 23,-0.1 -0.386 92.6 76.4 -70.2 145.4 24.9 40.0 -5.8 189 191 A G S S- 0 0 36 -3,-0.1 23,-0.4 -2,-0.1 21,-0.1 0.176 82.4 -90.5 119.4 120.8 21.5 38.5 -6.7 190 192 A E - 0 0 106 21,-0.2 2,-0.4 19,-0.1 21,-0.2 -0.291 34.6-169.6 -63.7 136.5 18.9 37.0 -4.4 191 193 A R E -J 210 0E 93 19,-1.8 19,-2.9 -8,-0.0 2,-0.5 -0.987 13.5-144.6-123.8 133.9 19.0 33.2 -3.6 192 194 A N E -J 209 0E 14 -2,-0.4 138,-2.4 136,-0.3 139,-1.4 -0.902 18.8-172.6-102.8 124.4 16.0 31.7 -1.8 193 195 A V E -Jk 208 331E 1 15,-3.0 15,-2.6 -2,-0.5 2,-0.5 -0.951 11.3-156.1-121.0 133.6 16.9 28.9 0.6 194 196 A L E -Jk 207 332E 0 137,-2.9 139,-2.9 -2,-0.4 2,-0.6 -0.940 4.9-160.4-111.5 125.6 14.5 26.6 2.5 195 197 A I E -Jk 206 333E 3 11,-3.0 11,-2.2 -2,-0.5 2,-0.6 -0.922 2.9-166.5-102.7 120.4 15.6 24.9 5.7 196 198 A F E -Jk 205 334E 0 137,-2.7 139,-2.5 -2,-0.6 2,-0.6 -0.940 9.0-174.2-111.0 110.5 13.5 21.9 6.7 197 199 A D E +Jk 204 335E 25 7,-2.8 7,-2.2 -2,-0.6 2,-0.4 -0.899 13.0 159.0-117.0 104.5 14.4 21.0 10.4 198 200 A L + 0 0 0 137,-2.2 140,-1.1 -2,-0.6 141,-0.7 -0.982 45.6 46.2-131.3 136.1 12.8 17.8 11.7 199 201 A G S S+ 0 0 19 27,-0.4 137,-0.1 -2,-0.4 -1,-0.1 0.148 87.6 88.0 125.8 -18.6 13.7 15.5 14.6 200 202 A G S S- 0 0 19 2,-0.5 28,-3.3 28,-0.1 29,-0.3 0.064 102.9 -57.3 -92.3-155.7 14.3 17.9 17.4 201 203 A G S S+ 0 0 7 26,-0.2 2,-0.3 27,-0.1 26,-0.2 0.746 120.6 4.1 -58.7 -27.8 12.1 19.5 20.0 202 204 A T S S- 0 0 24 24,-0.1 2,-0.6 25,-0.1 -2,-0.5 -0.961 78.1-105.0-150.9 168.3 9.9 21.0 17.3 203 205 A F E - L 0 223E 0 20,-1.0 20,-1.4 -2,-0.3 2,-0.4 -0.881 40.5-175.6-100.6 120.5 9.5 21.0 13.5 204 206 A D E -JL 197 222E 19 -7,-2.2 -7,-2.8 -2,-0.6 2,-0.4 -0.965 14.8-172.3-122.6 137.4 10.8 24.2 11.9 205 207 A V E -JL 196 221E 1 16,-3.0 16,-2.6 -2,-0.4 2,-0.4 -0.991 13.2-178.6-122.5 128.4 10.6 25.3 8.3 206 208 A S E -JL 195 220E 7 -11,-2.2 -11,-3.0 -2,-0.4 2,-0.5 -0.988 15.6-159.7-130.0 142.6 12.5 28.6 7.4 207 209 A I E -JL 194 219E 0 12,-2.6 11,-2.6 -2,-0.4 12,-1.5 -0.988 18.4-179.3-122.3 120.3 12.8 30.4 4.1 208 210 A L E -JL 193 217E 0 -15,-2.6 -15,-3.0 -2,-0.5 2,-0.5 -0.863 20.9-145.1-116.0 150.4 15.7 32.8 3.9 209 211 A T E -JL 192 216E 4 7,-2.6 7,-2.0 -2,-0.3 2,-0.5 -0.968 16.0-161.1-113.8 134.1 16.8 35.1 1.1 210 212 A I E +JL 191 215E 0 -19,-2.9 -19,-1.8 -2,-0.5 2,-0.4 -0.973 12.5 175.0-117.0 126.2 20.6 35.5 0.7 211 213 A D E > S- L 0 214E 36 3,-2.3 3,-1.8 -2,-0.5 -23,-0.2 -0.943 72.4 -27.2-135.0 111.1 21.9 38.4 -1.2 212 214 A D T 3 S- 0 0 93 -25,-1.8 -24,-0.2 -23,-0.4 -25,-0.1 0.904 127.8 -46.6 53.3 43.6 25.7 39.1 -1.4 213 215 A G T 3 S+ 0 0 29 -26,-0.3 2,-0.5 1,-0.2 -1,-0.3 0.461 111.6 122.9 80.4 -0.8 26.1 37.3 2.0 214 216 A I E < -L 211 0E 118 -3,-1.8 -3,-2.3 2,-0.0 2,-0.4 -0.855 49.8-149.2 -98.7 127.1 23.2 39.1 3.7 215 217 A F E -L 210 0E 51 -2,-0.5 2,-0.4 -5,-0.2 -5,-0.2 -0.810 15.4-179.6-100.0 135.8 20.5 36.9 5.2 216 218 A E E -L 209 0E 106 -7,-2.0 -7,-2.6 -2,-0.4 2,-0.7 -0.999 26.5-131.7-131.2 129.8 16.8 37.9 5.5 217 219 A V E +L 208 0E 58 -2,-0.4 -9,-0.2 -9,-0.2 3,-0.1 -0.737 26.6 176.3 -84.3 115.2 14.2 35.7 7.0 218 220 A K E - 0 0 59 -11,-2.6 2,-0.3 -2,-0.7 -10,-0.2 0.744 63.2 -7.9 -89.6 -28.9 11.2 35.6 4.6 219 221 A A E -L 207 0E 9 -12,-1.5 -12,-2.6 103,-0.1 2,-0.4 -0.961 52.0-162.9-167.3 148.7 9.0 33.2 6.4 220 222 A T E +L 206 0E 64 -2,-0.3 2,-0.3 -14,-0.2 -14,-0.2 -0.997 20.0 159.2-137.2 137.8 9.0 30.8 9.3 221 223 A A E +L 205 0E 15 -16,-2.6 -16,-3.0 -2,-0.4 2,-0.3 -0.929 4.2 147.0-148.3 168.8 6.5 28.0 9.9 222 224 A G E -L 204 0E 35 -2,-0.3 2,-0.3 -18,-0.2 -18,-0.2 -0.974 37.1-115.3-178.8-168.5 6.3 24.8 11.9 223 225 A D E > -L 203 0E 40 -20,-1.4 3,-1.8 -2,-0.3 -20,-1.0 -0.819 5.3-161.0-156.4 110.5 4.3 22.3 13.8 224 226 A T G > S+ 0 0 103 -2,-0.3 3,-0.5 1,-0.3 -20,-0.0 0.563 92.8 67.7 -72.2 -4.4 4.7 21.7 17.5 225 227 A H G 3 S+ 0 0 132 1,-0.2 -1,-0.3 -22,-0.1 -23,-0.1 0.413 92.3 63.1 -89.7 0.5 2.9 18.4 17.0 226 228 A L G < + 0 0 2 -3,-1.8 -27,-0.4 -23,-0.1 -1,-0.2 -0.133 67.6 137.5-117.2 37.0 5.8 17.1 15.0 227 229 A G S X> S- 0 0 0 -3,-0.5 3,-1.8 -26,-0.2 4,-1.0 -0.395 71.8-103.7 -73.8 162.5 8.6 17.1 17.5 228 230 A G H 3> S+ 0 0 3 -28,-3.3 4,-1.5 1,-0.3 3,-0.4 0.834 123.2 60.6 -55.4 -31.7 10.9 14.0 17.5 229 231 A E H 3> S+ 0 0 66 -29,-0.3 4,-2.2 1,-0.2 -1,-0.3 0.710 95.4 60.6 -67.8 -24.6 9.1 12.9 20.6 230 232 A D H <> S+ 0 0 44 -3,-1.8 4,-0.9 2,-0.2 -1,-0.2 0.834 105.9 46.7 -75.9 -29.4 5.8 12.7 18.7 231 233 A F H X S+ 0 0 0 -4,-1.0 4,-1.4 -3,-0.4 -2,-0.2 0.871 111.5 52.7 -76.6 -35.5 7.2 10.2 16.4 232 234 A D H X S+ 0 0 14 -4,-1.5 4,-3.0 1,-0.2 -2,-0.2 0.890 102.4 57.9 -64.6 -41.5 8.6 8.3 19.4 233 235 A N H X S+ 0 0 56 -4,-2.2 4,-2.8 1,-0.2 -1,-0.2 0.854 103.2 54.6 -57.7 -35.6 5.2 8.3 21.0 234 236 A R H X S+ 0 0 70 -4,-0.9 4,-2.0 2,-0.2 -1,-0.2 0.909 110.2 45.3 -65.1 -42.0 3.9 6.4 17.9 235 237 A L H X S+ 0 0 0 -4,-1.4 4,-2.3 2,-0.2 5,-0.2 0.930 112.5 52.1 -65.8 -44.5 6.5 3.8 18.4 236 238 A V H X S+ 0 0 3 -4,-3.0 4,-2.5 1,-0.2 5,-0.2 0.952 110.8 46.2 -56.4 -52.1 5.8 3.6 22.1 237 239 A N H X S+ 0 0 101 -4,-2.8 4,-2.3 1,-0.2 -1,-0.2 0.887 109.4 56.6 -59.9 -39.1 2.1 3.1 21.6 238 240 A H H X S+ 0 0 25 -4,-2.0 4,-1.8 1,-0.2 -1,-0.2 0.935 112.9 39.6 -56.4 -50.6 2.8 0.5 18.9 239 241 A F H X S+ 0 0 0 -4,-2.3 4,-3.0 2,-0.2 5,-0.2 0.796 110.6 57.4 -72.6 -29.7 4.9 -1.6 21.3 240 242 A V H X S+ 0 0 12 -4,-2.5 4,-1.9 -5,-0.2 11,-0.2 0.925 111.2 45.2 -64.8 -41.3 2.6 -1.1 24.2 241 243 A E H X S+ 0 0 78 -4,-2.3 4,-2.1 -5,-0.2 -2,-0.2 0.886 112.7 50.6 -67.4 -37.8 -0.1 -2.6 22.1 242 244 A E H < S+ 0 0 38 -4,-1.8 -2,-0.2 1,-0.2 -1,-0.2 0.936 110.9 48.0 -64.6 -46.8 2.1 -5.4 20.9 243 245 A F H >X S+ 0 0 0 -4,-3.0 4,-2.2 1,-0.2 3,-1.1 0.863 109.6 56.3 -61.7 -36.3 3.1 -6.2 24.5 244 246 A K H 3X S+ 0 0 64 -4,-1.9 4,-1.6 1,-0.2 -1,-0.2 0.917 106.2 45.9 -66.0 -44.9 -0.6 -6.2 25.4 245 247 A R H 3< S+ 0 0 162 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.217 117.1 47.6 -86.4 21.9 -1.8 -8.7 22.9 246 248 A K H <4 S+ 0 0 119 -3,-1.1 -2,-0.2 3,-0.2 -1,-0.2 0.618 129.6 16.8-121.4 -40.0 1.1 -11.0 23.8 247 249 A H H < S- 0 0 43 -4,-2.2 -2,-0.2 2,-0.2 -3,-0.2 0.324 94.8-124.3-117.1 1.8 1.0 -11.0 27.6 248 250 A K S < S+ 0 0 177 -4,-1.6 2,-0.4 -5,-0.3 -4,-0.2 0.796 73.1 126.7 56.8 27.6 -2.6 -9.6 28.0 249 251 A K - 0 0 74 -6,-0.6 2,-0.7 -5,-0.2 -2,-0.2 -0.959 55.3-147.1-122.7 137.6 -0.9 -6.9 30.1 250 252 A D > + 0 0 74 -2,-0.4 3,-0.5 1,-0.1 4,-0.1 -0.887 15.0 179.0-103.4 108.1 -1.2 -3.1 29.7 251 253 A I G > + 0 0 0 -2,-0.7 3,-1.5 -11,-0.2 7,-0.4 0.450 54.0 103.5 -87.8 0.1 2.0 -1.5 30.8 252 254 A S G 3 S+ 0 0 52 1,-0.3 -1,-0.2 -12,-0.1 -12,-0.0 0.690 80.8 48.5 -58.3 -21.0 0.8 2.1 30.1 253 255 A Q G < S+ 0 0 157 -3,-0.5 2,-1.1 1,-0.1 -1,-0.3 0.616 88.1 90.7 -94.2 -13.1 0.2 2.9 33.7 254 256 A N <> - 0 0 66 -3,-1.5 4,-2.2 1,-0.2 5,-0.2 -0.719 64.3-162.0 -84.9 101.8 3.6 1.6 34.9 255 257 A K H > S+ 0 0 157 -2,-1.1 4,-1.2 1,-0.2 -1,-0.2 0.759 85.4 49.4 -59.2 -26.4 5.7 4.8 34.6 256 258 A R H > S+ 0 0 140 2,-0.2 4,-2.0 1,-0.1 5,-0.2 0.918 108.3 51.3 -79.8 -43.1 9.0 3.0 34.7 257 259 A A H > S+ 0 0 3 1,-0.2 4,-1.8 2,-0.2 5,-0.2 0.934 110.8 50.2 -56.9 -46.7 8.1 0.5 32.0 258 260 A V H X S+ 0 0 23 -4,-2.2 4,-1.9 -7,-0.4 -1,-0.2 0.878 106.8 55.3 -62.0 -37.1 7.0 3.3 29.7 259 261 A R H X S+ 0 0 69 -4,-1.2 4,-2.4 -5,-0.2 -1,-0.2 0.942 110.0 43.7 -60.3 -51.0 10.2 5.2 30.3 260 262 A R H X S+ 0 0 83 -4,-2.0 4,-2.4 1,-0.2 -1,-0.2 0.824 112.7 52.7 -65.1 -33.4 12.5 2.4 29.2 261 263 A L H X S+ 0 0 0 -4,-1.8 4,-2.2 -5,-0.2 -1,-0.2 0.864 107.9 52.3 -71.1 -32.7 10.3 1.6 26.2 262 264 A R H X S+ 0 0 111 -4,-1.9 4,-2.5 2,-0.2 5,-0.2 0.970 109.1 49.1 -64.2 -51.9 10.5 5.2 25.2 263 265 A T H X S+ 0 0 38 -4,-2.4 4,-2.1 1,-0.2 -2,-0.2 0.914 111.1 50.3 -53.0 -47.7 14.3 5.0 25.4 264 266 A A H X S+ 0 0 6 -4,-2.4 4,-2.4 1,-0.2 -1,-0.2 0.891 109.9 50.8 -59.3 -42.4 14.3 1.8 23.3 265 267 A C H X S+ 0 0 0 -4,-2.2 4,-3.2 2,-0.2 -2,-0.2 0.923 106.7 51.2 -65.3 -47.5 12.0 3.5 20.6 266 268 A E H X S+ 0 0 32 -4,-2.5 4,-1.9 1,-0.2 -1,-0.2 0.974 112.9 48.2 -52.7 -52.3 14.1 6.6 20.2 267 269 A R H X S+ 0 0 135 -4,-2.1 4,-1.6 1,-0.2 -2,-0.2 0.902 112.2 50.2 -52.2 -45.0 17.1 4.2 19.7 268 270 A A H X S+ 0 0 3 -4,-2.4 4,-1.7 1,-0.2 -1,-0.2 0.925 104.1 57.1 -61.8 -47.3 15.0 2.2 17.2 269 271 A K H < S+ 0 0 15 -4,-3.2 4,-0.4 1,-0.2 3,-0.4 0.927 105.9 51.4 -50.0 -51.5 14.0 5.2 15.2 270 272 A R H >X S+ 0 0 114 -4,-1.9 3,-2.3 1,-0.2 4,-0.7 0.952 109.2 46.7 -52.3 -60.1 17.6 6.2 14.5 271 273 A T H 3X S+ 0 0 66 -4,-1.6 4,-3.8 1,-0.3 3,-0.4 0.757 101.0 69.6 -58.4 -24.1 18.8 2.8 13.2 272 274 A L H 3< S+ 0 0 3 -4,-1.7 -1,-0.3 -3,-0.4 -2,-0.2 0.652 90.8 61.2 -69.6 -13.8 15.7 2.5 11.0 273 275 A S H <4 S+ 0 0 19 -3,-2.3 -1,-0.2 -4,-0.4 -2,-0.2 0.886 119.1 26.1 -76.6 -38.7 17.1 5.3 8.9 274 276 A S H < S+ 0 0 110 -4,-0.7 -2,-0.2 -3,-0.4 2,-0.2 0.753 125.1 52.2 -93.4 -30.7 20.1 3.2 8.1 275 277 A S < - 0 0 30 -4,-3.8 3,-0.1 -5,-0.2 21,-0.0 -0.501 67.7-140.3-101.7 174.2 18.5 -0.2 8.5 276 278 A T S S+ 0 0 68 -2,-0.2 21,-1.4 1,-0.2 2,-0.3 0.262 95.4 35.8-109.8 3.7 15.4 -1.8 7.1 277 279 A Q E -N 296 0F 109 19,-0.3 2,-0.4 -6,-0.2 19,-0.2 -0.993 63.8-163.6-154.2 150.2 14.9 -3.3 10.6 278 280 A A E -N 295 0F 2 17,-1.9 17,-2.5 -2,-0.3 2,-0.4 -0.999 14.7-141.2-140.4 136.6 15.5 -2.4 14.3 279 281 A S E -N 294 0F 85 -2,-0.4 2,-0.5 15,-0.2 15,-0.3 -0.782 4.3-158.0-102.9 141.0 15.6 -4.6 17.3 280 282 A L E +N 293 0F 3 13,-3.4 13,-2.9 -2,-0.4 2,-0.3 -0.968 13.6 176.0-113.4 128.4 14.3 -3.9 20.8 281 283 A E E +N 292 0F 118 -2,-0.5 2,-0.6 11,-0.2 11,-0.2 -0.711 7.3 164.8-138.3 84.4 15.8 -6.0 23.6 282 284 A I E -N 291 0F 4 9,-3.2 9,-3.1 -2,-0.3 3,-0.5 -0.894 25.9-146.4-106.5 118.1 14.5 -5.0 27.0 283 285 A D E S- 0 0 94 -2,-0.6 7,-0.2 1,-0.2 6,-0.1 -0.694 80.0 -4.6 -84.5 132.4 15.2 -7.3 29.9 284 286 A S E S+ 0 0 73 -2,-0.4 6,-0.3 4,-0.4 -1,-0.2 0.962 75.3 165.7 49.9 66.2 12.4 -7.4 32.6 285 287 A L E + 0 0 14 4,-3.2 2,-0.4 -3,-0.5 5,-0.2 0.945 66.3 10.5 -72.7 -50.4 10.2 -4.6 31.1 286 288 A F E > S-N 289 0F 22 3,-1.1 3,-3.4 1,-0.1 -1,-0.3 -0.996 136.0 -16.5-138.2 130.2 7.1 -5.3 33.1 287 289 A E T 3 S- 0 0 131 -2,-0.4 -1,-0.1 1,-0.3 -2,-0.1 0.895 127.9 -54.1 41.8 48.8 6.6 -7.6 36.1 288 290 A G T 3 S+ 0 0 54 -4,-0.2 -4,-0.4 1,-0.2 -1,-0.3 0.317 104.3 140.7 72.8 -8.7 9.9 -9.3 35.2 289 291 A I E < -N 286 0F 34 -3,-3.4 -4,-3.2 -5,-0.2 -3,-1.1 -0.441 46.3-136.1 -69.9 136.0 8.7 -10.0 31.7 290 292 A D E - 0 0 77 -6,-0.3 2,-0.5 -5,-0.2 -7,-0.2 -0.692 10.2-154.4 -93.0 147.8 11.3 -9.5 29.0 291 293 A F E +N 282 0F 4 -9,-3.1 -9,-3.2 -2,-0.3 2,-0.5 -0.932 21.6 163.1-127.9 104.4 10.5 -7.7 25.7 292 294 A Y E +N 281 0F 117 -2,-0.5 2,-0.3 -11,-0.2 -11,-0.2 -0.990 25.4 119.9-120.9 122.7 12.6 -8.6 22.6 293 295 A T E -N 280 0F 33 -13,-2.9 -13,-3.4 -2,-0.5 2,-0.3 -0.861 40.0-138.0-160.0-164.8 11.1 -7.6 19.3 294 296 A S E -N 279 0F 64 -15,-0.3 2,-0.4 -2,-0.3 -15,-0.2 -0.986 4.1-139.9-163.5 165.6 11.8 -5.6 16.3 295 297 A I E -N 278 0F 5 -17,-2.5 -17,-1.9 -2,-0.3 2,-0.3 -1.000 15.9-133.0-138.3 139.7 10.2 -3.2 13.8 296 298 A T E >> -N 277 0F 64 -2,-0.4 4,-2.4 -19,-0.2 3,-1.1 -0.634 26.7-117.3 -90.0 149.4 10.6 -2.9 10.1 297 299 A R H 3> S+ 0 0 58 -21,-1.4 4,-4.3 -2,-0.3 5,-0.2 0.796 112.1 45.5 -56.7 -33.9 11.1 0.6 8.6 298 300 A A H 34 S+ 0 0 60 -22,-0.3 4,-0.4 2,-0.3 -1,-0.3 0.606 109.5 54.5 -88.4 -11.1 7.9 0.7 6.5 299 301 A R H <> S+ 0 0 100 -3,-1.1 4,-2.8 3,-0.2 -2,-0.2 0.862 119.2 38.2 -78.0 -39.9 5.9 -0.6 9.4 300 302 A F H X S+ 0 0 1 -4,-2.4 4,-2.2 2,-0.3 -2,-0.3 0.931 116.9 45.9 -70.6 -53.0 7.5 2.4 11.0 301 303 A E H < S+ 0 0 27 -4,-4.3 -3,-0.2 1,-0.2 -1,-0.2 0.798 120.3 45.9 -62.6 -23.7 7.4 4.8 8.1 302 304 A E H >4 S+ 0 0 104 -4,-0.4 3,-1.2 2,-0.2 4,-0.4 0.874 106.6 55.7 -81.3 -44.0 3.8 3.5 7.9 303 305 A L H 3< S+ 0 0 27 -4,-2.8 -2,-0.2 1,-0.3 -3,-0.2 0.826 122.4 30.1 -58.6 -30.8 3.2 3.8 11.6 304 306 A C T 3X S+ 0 0 0 -4,-2.2 4,-2.7 1,-0.1 3,-0.4 0.230 84.0 117.9-113.1 13.1 4.2 7.5 11.2 305 307 A S H <> S+ 0 0 38 -3,-1.2 4,-2.5 1,-0.2 5,-0.2 0.847 78.5 47.8 -50.6 -42.1 3.0 8.1 7.6 306 308 A D H > S+ 0 0 58 -4,-0.4 4,-2.2 2,-0.2 -1,-0.2 0.892 112.1 49.6 -68.4 -38.0 0.5 10.7 8.6 307 309 A L H > S+ 0 0 20 -3,-0.4 4,-0.6 2,-0.2 -2,-0.2 0.937 113.5 45.5 -66.4 -45.3 3.0 12.6 10.8 308 310 A F H >< S+ 0 0 1 -4,-2.7 3,-1.3 1,-0.2 4,-0.3 0.923 112.1 51.1 -63.2 -43.5 5.6 12.6 8.0 309 311 A R H >< S+ 0 0 144 -4,-2.5 3,-1.9 -5,-0.3 4,-0.3 0.903 102.0 63.9 -60.9 -37.7 3.1 13.7 5.4 310 312 A S H >< S+ 0 0 50 -4,-2.2 3,-1.2 1,-0.3 -1,-0.3 0.702 83.6 76.2 -59.3 -22.3 2.0 16.5 7.8 311 313 A T T S+ 0 0 25 -3,-1.9 4,-2.5 -4,-0.3 -1,-0.2 0.716 87.1 69.7 -80.3 -19.0 4.5 19.4 4.1 313 315 A E H <> S+ 0 0 100 -3,-1.2 4,-2.6 -4,-0.3 -1,-0.2 0.949 100.3 46.2 -64.5 -46.2 1.7 21.6 5.3 314 316 A P H > S+ 0 0 7 0, 0.0 4,-2.8 0, 0.0 -1,-0.2 0.851 111.5 54.1 -66.1 -27.3 4.1 24.1 7.0 315 317 A V H X S+ 0 0 0 -4,-0.8 4,-2.2 2,-0.2 -2,-0.2 0.943 109.4 46.2 -66.9 -45.2 6.3 24.0 3.9 316 318 A E H X S+ 0 0 91 -4,-2.5 4,-2.1 1,-0.2 -1,-0.2 0.933 114.2 49.7 -62.3 -44.1 3.3 25.0 1.7 317 319 A K H X S+ 0 0 90 -4,-2.6 4,-3.0 1,-0.2 5,-0.2 0.921 108.8 51.2 -60.9 -47.3 2.4 27.7 4.3 318 320 A A H X S+ 0 0 0 -4,-2.8 4,-2.5 1,-0.2 -1,-0.2 0.892 110.5 48.8 -58.8 -42.6 5.9 29.1 4.4 319 321 A L H X>S+ 0 0 9 -4,-2.2 5,-2.5 2,-0.2 4,-0.7 0.898 111.7 50.2 -63.0 -41.3 6.1 29.4 0.6 320 322 A R H ><5S+ 0 0 142 -4,-2.1 3,-0.8 3,-0.2 -2,-0.2 0.948 113.4 45.2 -62.5 -48.3 2.7 31.1 0.6 321 323 A D H 3<5S+ 0 0 80 -4,-3.0 -2,-0.2 1,-0.2 -1,-0.2 0.862 114.1 48.0 -65.0 -34.8 3.8 33.6 3.3 322 324 A A H 3<5S- 0 0 13 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.568 109.2-128.4 -80.8 -6.6 7.2 34.2 1.5 323 325 A K T <<5 + 0 0 184 -3,-0.8 2,-0.3 -4,-0.7 -3,-0.2 0.866 63.3 132.9 60.3 41.4 5.2 34.7 -1.7 324 326 A L < - 0 0 23 -5,-2.5 -1,-0.2 -6,-0.1 2,-0.2 -0.910 52.8-133.3-121.8 148.5 7.3 32.2 -3.6 325 327 A D > - 0 0 117 -2,-0.3 3,-2.0 -3,-0.1 4,-0.3 -0.600 35.1-106.6 -90.9 161.4 6.5 29.3 -5.9 326 328 A K G > S+ 0 0 64 1,-0.3 3,-1.9 -2,-0.2 -1,-0.1 0.899 121.4 58.6 -52.9 -43.4 8.3 25.9 -5.3 327 329 A A G 3 S+ 0 0 89 1,-0.3 -1,-0.3 3,-0.0 25,-0.0 0.640 96.1 63.7 -63.6 -15.5 10.3 26.6 -8.4 328 330 A Q G < S+ 0 0 89 -3,-2.0 2,-0.5 -137,-0.0 -136,-0.3 0.487 77.9 97.2 -88.4 -3.6 11.6 29.8 -6.9 329 331 A I < - 0 0 2 -3,-1.9 -136,-0.2 -4,-0.3 3,-0.1 -0.768 55.4-168.7 -84.6 126.5 13.5 28.0 -4.1 330 332 A H + 0 0 75 -138,-2.4 2,-0.3 -2,-0.5 -137,-0.2 0.770 66.6 20.4 -86.3 -29.6 17.1 27.7 -5.1 331 333 A D E -k 193 0E 28 -139,-1.4 -137,-2.9 2,-0.0 2,-0.5 -0.996 57.4-153.5-146.6 140.6 18.2 25.2 -2.4 332 334 A L E -k 194 0E 1 24,-0.4 26,-2.5 -2,-0.3 2,-0.5 -0.944 19.8-164.6-110.5 128.3 16.6 22.8 0.0 333 335 A V E -km 195 358E 0 -139,-2.9 -137,-2.7 -2,-0.5 2,-0.4 -0.962 7.9-145.2-122.6 128.4 18.6 22.1 3.3 334 336 A L E +k 196 0E 1 24,-1.9 2,-0.3 -2,-0.5 -137,-0.2 -0.710 23.3 166.1 -92.4 128.9 18.1 19.3 5.7 335 337 A V E +k 197 0E 6 -139,-2.5 -137,-2.2 -2,-0.4 29,-0.3 -0.989 38.6 47.5-137.9 151.7 18.5 19.6 9.4 336 338 A G S > S- 0 0 8 27,-1.8 3,-1.8 -2,-0.3 28,-0.2 0.254 85.1 -90.5 97.5 141.8 17.5 17.4 12.3 337 339 A G G > S+ 0 0 39 1,-0.3 3,-1.5 26,-0.2 -138,-0.2 0.805 118.1 62.0 -55.5 -34.9 17.9 13.7 12.8 338 340 A S G > S+ 0 0 3 -140,-1.1 3,-1.3 1,-0.3 -1,-0.3 0.618 84.7 76.2 -72.2 -9.9 14.6 12.7 11.3 339 341 A T G < S+ 0 0 0 -3,-1.8 -1,-0.3 -141,-0.7 -2,-0.2 0.549 84.2 66.0 -77.8 -4.1 15.5 14.1 7.9 340 342 A R G < S+ 0 0 88 -3,-1.5 -1,-0.3 -4,-0.2 -2,-0.2 0.551 74.1 108.5 -89.8 -3.9 17.7 11.1 7.3 341 343 A I S X> S- 0 0 5 -3,-1.3 4,-1.7 1,-0.2 3,-0.7 -0.549 74.0-136.0 -68.8 124.4 14.6 8.9 7.3 342 344 A P H 3> S+ 0 0 45 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.878 101.4 55.9 -50.6 -42.2 14.1 7.9 3.6 343 345 A K H 3> S+ 0 0 67 1,-0.2 4,-2.4 2,-0.2 5,-0.1 0.884 106.3 51.4 -59.9 -38.5 10.3 8.6 3.6 344 346 A V H <> S+ 0 0 2 -3,-0.7 4,-2.1 -6,-0.2 -1,-0.2 0.903 109.9 47.8 -66.3 -43.0 10.9 12.1 4.8 345 347 A Q H X S+ 0 0 34 -4,-1.7 4,-2.7 2,-0.2 5,-0.2 0.900 111.3 51.6 -64.8 -40.5 13.4 12.8 2.0 346 348 A K H X S+ 0 0 102 -4,-2.4 4,-3.1 -5,-0.2 5,-0.3 0.929 109.1 51.0 -61.7 -45.5 11.1 11.3 -0.6 347 349 A L H X S+ 0 0 27 -4,-2.4 4,-2.4 2,-0.2 -2,-0.2 0.928 114.5 41.8 -60.1 -45.8 8.2 13.5 0.6 348 350 A L H X S+ 0 0 1 -4,-2.1 4,-1.8 2,-0.2 -1,-0.2 0.923 116.7 48.3 -68.5 -43.8 10.2 16.8 0.4 349 351 A Q H <>S+ 0 0 70 -4,-2.7 5,-2.4 1,-0.2 6,-0.9 0.905 114.7 45.6 -61.7 -44.7 11.8 15.8 -2.9 350 352 A D H ><5S+ 0 0 78 -4,-3.1 3,-2.0 3,-0.2 -1,-0.2 0.899 108.9 55.2 -65.7 -41.9 8.5 14.9 -4.4 351 353 A F H 3<5S+ 0 0 24 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.874 109.7 48.3 -60.2 -35.5 6.8 18.0 -3.1 352 354 A F T 3<5S- 0 0 5 -4,-1.8 3,-0.4 -5,-0.2 -1,-0.3 0.104 122.8-108.2 -92.5 24.1 9.5 20.0 -4.9 353 355 A N T < 5S- 0 0 131 -3,-2.0 -3,-0.2 1,-0.2 -2,-0.1 0.864 81.1 -36.5 56.2 45.4 9.0 18.0 -8.1 354 356 A G S > - 0 0 52 -2,-0.5 3,-2.3 1,-0.2 4,-1.0 -0.202 37.1-132.7 -41.6 124.2 24.7 14.8 8.8 363 365 A P T 34 S+ 0 0 2 0, 0.0 -27,-1.8 0, 0.0 4,-0.4 0.794 103.3 56.3 -58.2 -30.7 21.5 16.8 9.3 364 366 A D T 34 S+ 0 0 56 -29,-0.3 4,-0.2 -28,-0.2 -27,-0.1 0.468 113.3 43.2 -80.2 4.3 21.7 16.8 13.1 365 367 A E T <> S+ 0 0 8 -3,-2.3 4,-2.4 -29,-0.1 -1,-0.2 0.477 86.6 91.3-120.2 -10.1 25.2 18.4 12.8 366 368 A A H X S+ 0 0 0 -4,-1.0 4,-2.3 -3,-0.3 5,-0.2 0.840 85.5 51.1 -59.4 -39.3 24.6 21.0 10.1 367 369 A V H > S+ 0 0 6 -4,-0.4 4,-2.3 2,-0.2 -1,-0.2 0.955 113.1 44.2 -66.3 -46.8 23.8 23.8 12.5 368 370 A A H > S+ 0 0 0 1,-0.2 4,-2.2 2,-0.2 -351,-0.3 0.870 111.4 56.4 -64.0 -35.8 26.9 23.3 14.6 369 371 A Y H X S+ 0 0 55 -4,-2.4 4,-2.0 1,-0.2 -1,-0.2 0.945 109.8 44.1 -59.9 -48.4 28.9 23.0 11.4 370 372 A G H X S+ 0 0 0 -4,-2.3 4,-2.5 1,-0.2 -2,-0.2 0.880 111.2 53.2 -65.6 -36.7 27.7 26.4 10.2 371 373 A A H X S+ 0 0 0 -4,-2.3 4,-2.2 1,-0.2 -1,-0.2 0.887 108.6 51.9 -64.9 -35.8 28.3 27.9 13.6 372 374 A A H X S+ 0 0 0 -4,-2.2 4,-2.0 -366,-0.2 -353,-0.4 0.880 108.5 49.5 -68.5 -40.1 31.8 26.6 13.5 373 375 A V H X S+ 0 0 37 -4,-2.0 4,-2.3 2,-0.2 -2,-0.2 0.952 113.0 47.6 -62.4 -48.4 32.5 28.1 10.0 374 376 A Q H X S+ 0 0 28 -4,-2.5 4,-2.6 1,-0.2 -2,-0.2 0.880 108.8 53.8 -61.7 -38.6 31.1 31.5 11.3 375 377 A A H X S+ 0 0 0 -4,-2.2 4,-1.7 1,-0.2 -1,-0.2 0.930 109.5 48.2 -62.5 -42.8 33.2 31.3 14.4 376 378 A A H X>S+ 0 0 6 -4,-2.0 5,-2.6 2,-0.2 4,-1.9 0.909 110.0 52.2 -64.4 -40.7 36.3 30.8 12.3 377 379 A I H <5S+ 0 0 114 -4,-2.3 -1,-0.2 1,-0.2 -2,-0.2 0.934 110.9 47.4 -59.6 -46.8 35.4 33.7 10.1 378 380 A L H <5S+ 0 0 59 -4,-2.6 -1,-0.2 1,-0.2 -2,-0.2 0.794 113.0 48.5 -67.0 -28.5 35.0 36.0 13.1 379 381 A M H <5S- 0 0 71 -4,-1.7 -1,-0.2 -5,-0.2 -2,-0.2 0.771 113.4-118.8 -80.5 -27.3 38.3 34.9 14.5 380 382 A G T <5 0 0 68 -4,-1.9 -3,-0.2 -5,-0.2 -2,-0.1 0.854 360.0 360.0 89.8 41.4 40.1 35.4 11.2 381 383 A D < 0 0 91 -5,-2.6 -4,-0.2 -6,-0.1 -5,-0.1 0.562 360.0 360.0-141.5 360.0 41.2 31.8 10.8