==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=27-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER COMPLEX (CYTOKINE RECEPTOR/PEPTIDE) 07-MAY-96 1EBP . COMPND 2 MOLECULE: EPO RECEPTOR; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR O.LIVNAH,E.A.STURA,I.A.WILSON . 454 4 6 6 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 25512.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 271 59.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 9 2.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 154 33.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 4 0.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 36 7.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 37 8.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 3.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 1 7 5 2 2 5 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 4 6 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 10 A K >> 0 0 190 0, 0.0 4,-2.2 0, 0.0 3,-1.4 0.000 360.0 360.0 360.0 -87.4 39.6 30.1 21.0 2 11 A F H 3> + 0 0 173 1,-0.3 4,-2.8 2,-0.2 5,-0.3 0.786 360.0 43.3 -33.4 -55.0 36.9 32.6 22.0 3 12 A E H 3> S+ 0 0 163 1,-0.2 4,-2.5 2,-0.2 -1,-0.3 0.888 116.3 50.6 -65.1 -33.2 38.9 34.0 24.9 4 13 A S H <> S+ 0 0 57 -3,-1.4 4,-3.3 2,-0.2 -2,-0.2 0.958 114.4 40.6 -65.1 -54.1 41.9 34.1 22.6 5 14 A K H X S+ 0 0 136 -4,-2.2 4,-0.8 2,-0.3 -2,-0.2 0.834 116.6 50.8 -62.5 -35.9 40.1 35.9 19.7 6 15 A A H >X S+ 0 0 45 -4,-2.8 3,-1.0 -5,-0.4 4,-0.7 0.936 111.2 48.7 -66.3 -44.9 38.4 38.2 22.2 7 16 A A H >< S+ 0 0 33 -4,-2.5 3,-2.0 -5,-0.3 -2,-0.3 0.971 108.0 56.1 -56.6 -50.6 41.8 38.8 23.6 8 17 A L H 3< S+ 0 0 69 -4,-3.3 -1,-0.3 1,-0.3 -2,-0.2 0.601 109.3 44.7 -57.4 -21.1 43.0 39.5 20.0 9 18 A L H << S+ 0 0 157 -3,-1.0 -1,-0.3 -4,-0.8 -2,-0.2 0.424 90.5 116.2-103.8 -3.2 40.4 42.2 19.4 10 19 A A << - 0 0 66 -3,-2.0 -3,-0.1 -4,-0.7 -4,-0.0 0.097 68.1 -97.2 -58.4 177.4 40.9 43.9 22.8 11 20 A A - 0 0 75 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 0.126 34.3-143.0 -81.2-163.9 42.2 47.5 23.3 12 21 A R - 0 0 191 0, 0.0 0, 0.0 0, 0.0 0, 0.0 -0.888 9.0-152.8-172.5 139.2 45.8 48.7 24.1 13 22 A G - 0 0 64 1,-0.3 3,-0.1 -2,-0.3 0, 0.0 -0.264 43.6 -80.2 -96.4-174.3 47.7 51.2 26.0 14 23 A P - 0 0 122 0, 0.0 -1,-0.3 0, 0.0 2,-0.1 -0.029 67.3 -51.7 -77.2-171.5 51.3 52.5 25.1 15 24 A E + 0 0 87 16,-0.1 2,-0.3 2,-0.0 18,-0.1 -0.368 62.3 172.4 -60.4 138.5 54.7 51.0 25.7 16 25 A E - 0 0 132 16,-0.2 2,-0.5 -3,-0.1 16,-0.3 -0.929 34.9-122.1-159.3 128.4 55.4 50.0 29.3 17 26 A L - 0 0 7 -2,-0.3 2,-0.5 14,-0.1 14,-0.2 -0.609 33.8-159.8 -71.8 120.7 58.1 48.0 31.0 18 27 A L E +A 30 0A 74 12,-3.2 12,-2.2 -2,-0.5 2,-0.3 -0.916 17.2 167.1-116.5 121.5 56.6 45.0 32.7 19 28 A a E +A 29 0A 3 -2,-0.5 2,-0.3 10,-0.3 10,-0.2 -0.859 2.0 165.1-124.4 154.4 58.2 43.0 35.6 20 29 A F E -A 28 0A 39 8,-1.9 8,-2.2 -2,-0.3 2,-0.3 -0.962 24.6-139.5-164.1 154.7 56.8 40.4 37.9 21 30 A T B -d 110 0B 0 88,-2.0 90,-2.9 -2,-0.3 6,-0.1 -0.926 11.5-175.2-118.2 148.3 58.0 37.7 40.5 22 31 A E S S+ 0 0 51 1,-0.4 91,-0.4 -2,-0.3 2,-0.3 0.729 77.4 12.5-111.4 -48.2 56.4 34.2 40.8 23 32 A R S S- 0 0 54 89,-0.1 3,-0.4 116,-0.1 -1,-0.4 -0.669 103.1 -94.7-114.2 177.9 58.0 32.4 43.7 24 33 A L S S+ 0 0 6 -2,-0.3 59,-0.1 1,-0.2 406,-0.1 0.295 113.5 60.2 -96.6 30.7 60.1 34.7 45.7 25 34 A E S S+ 0 0 105 57,-0.1 2,-0.3 81,-0.0 -1,-0.2 -0.352 94.5 64.5-137.6 51.1 63.5 34.2 44.1 26 35 A D - 0 0 31 -3,-0.4 2,-0.3 55,-0.2 -4,-0.1 -0.980 51.4-165.0-167.6 155.5 63.0 35.2 40.5 27 36 A L - 0 0 2 49,-0.5 49,-1.2 -2,-0.3 2,-0.4 -0.980 1.6-168.3-151.9 137.9 62.1 38.3 38.3 28 37 A V E -AB 20 75A 24 -8,-2.2 -8,-1.9 -2,-0.3 2,-0.3 -0.985 8.2-177.5-127.7 134.9 61.0 38.6 34.7 29 38 A a E +AB 19 74A 2 45,-1.9 45,-0.8 -2,-0.4 2,-0.3 -0.994 12.6 152.3-133.0 143.7 60.8 41.9 32.8 30 39 A F E -AB 18 73A 41 -12,-2.2 -12,-3.2 -2,-0.3 2,-0.3 -0.966 23.4-160.0-161.2 166.4 59.6 42.5 29.3 31 40 A W E - B 0 72A 1 41,-2.1 41,-2.5 -2,-0.3 2,-0.2 -0.976 17.0-138.0-152.8 145.0 58.1 45.0 26.8 32 41 A E E + B 0 71A 57 -2,-0.3 2,-0.3 -16,-0.3 39,-0.2 -0.691 27.7 150.7-106.8 161.3 56.3 44.5 23.6 33 42 A E E - B 0 70A 31 37,-1.4 37,-2.8 -2,-0.2 2,-0.2 -0.953 45.7 -57.5-166.4-175.7 56.4 46.4 20.2 34 43 A A E - B 0 69A 75 -2,-0.3 35,-0.2 35,-0.3 34,-0.1 -0.534 57.9 -95.9 -81.9 146.6 56.0 46.0 16.4 35 44 A A - 0 0 65 33,-0.9 2,-0.4 -2,-0.2 -1,-0.1 -0.087 44.1-156.4 -54.5 150.2 57.9 43.5 14.2 36 45 A S > - 0 0 77 3,-0.2 3,-0.9 0, 0.0 2,-0.5 -0.985 22.4-123.7-145.2 134.7 61.0 44.9 12.5 37 46 A A T 3 S+ 0 0 103 -2,-0.4 0, 0.0 1,-0.3 0, 0.0 -0.611 104.0 1.3 -68.4 113.6 63.0 44.1 9.5 38 47 A G T 3 S+ 0 0 78 -2,-0.5 2,-0.4 1,-0.2 -1,-0.3 0.941 96.7 123.5 69.7 53.6 66.5 43.8 11.0 39 48 A V < + 0 0 42 -3,-0.9 -3,-0.2 0, 0.0 -1,-0.2 -0.981 28.4 164.9-142.4 127.4 66.0 44.3 14.8 40 49 A G > - 0 0 24 -2,-0.4 3,-1.9 1,-0.0 4,-0.1 -0.780 55.6 -85.4-133.0 179.7 66.9 41.8 17.4 41 50 A P G > S+ 0 0 45 0, 0.0 3,-1.4 0, 0.0 19,-0.2 0.843 120.4 69.9 -58.2 -27.6 67.5 41.5 21.1 42 51 A G G 3 S+ 0 0 71 1,-0.3 3,-0.0 17,-0.1 19,-0.0 0.349 80.0 78.9 -73.2 10.8 71.1 42.8 20.5 43 52 A N G < S+ 0 0 67 -3,-1.9 51,-3.1 50,-0.1 2,-0.3 0.551 96.7 37.0 -95.1 -10.0 69.7 46.2 19.6 44 53 A Y E < S-F 93 0C 28 -3,-1.4 2,-0.5 49,-0.3 49,-0.3 -0.962 72.7-132.0-136.0 160.2 69.1 47.4 23.2 45 54 A S E -F 92 0C 61 47,-3.3 47,-2.6 -2,-0.3 2,-0.7 -0.940 13.4-157.0-116.8 128.1 71.0 46.9 26.5 46 55 A F E +FG 91 58C 2 12,-0.7 12,-3.5 -2,-0.5 2,-0.3 -0.894 22.2 170.5-108.3 103.0 69.1 45.9 29.6 47 56 A S E -FG 90 57C 9 43,-2.4 43,-1.6 -2,-0.7 2,-0.3 -0.860 11.5-169.5-118.1 150.8 70.9 46.9 32.8 48 57 A Y E -FG 89 56C 3 8,-2.1 8,-2.2 -2,-0.3 2,-0.3 -0.837 12.6-155.5-129.9 163.9 69.9 46.9 36.5 49 58 A Q E -F 88 0C 58 39,-1.7 39,-2.6 -2,-0.3 2,-0.7 -0.833 6.1-158.9-144.8 102.4 71.2 48.1 39.8 50 59 A L E > -F 87 0C 15 4,-0.4 3,-1.9 -2,-0.3 37,-0.2 -0.780 57.0 -81.3 -79.2 115.8 70.2 46.4 43.0 51 60 A E T 3 S- 0 0 115 35,-2.0 -1,-0.1 -2,-0.7 36,-0.0 0.155 112.7 -0.3 -29.6 118.3 70.8 49.3 45.6 52 61 A D T 3 S+ 0 0 163 1,-0.4 -1,-0.3 -3,-0.0 -3,-0.0 0.654 109.4 103.3 67.5 22.4 74.5 49.4 46.5 53 62 A E S < S- 0 0 29 -3,-1.9 -1,-0.4 3,-0.0 2,-0.1 -0.814 83.6-100.8-113.3 153.8 75.4 46.5 44.2 54 63 A P - 0 0 89 0, 0.0 -4,-0.4 0, 0.0 -6,-0.1 -0.421 45.3 -79.6 -78.8 161.4 77.1 47.7 41.0 55 64 A W + 0 0 98 -6,-0.1 2,-0.3 -2,-0.1 -6,-0.2 -0.325 56.5 179.4 -59.8 134.7 75.3 48.1 37.6 56 65 A K E -G 48 0C 73 -8,-2.2 -8,-2.1 -3,-0.1 2,-0.4 -0.843 20.5-119.0-130.5 174.1 74.9 44.8 35.8 57 66 A L E -G 47 0C 119 -2,-0.3 2,-0.4 -10,-0.2 -10,-0.2 -0.897 10.3-160.1-122.3 145.6 73.4 43.5 32.6 58 67 A b E -G 46 0C 18 -12,-3.5 -12,-0.7 -2,-0.4 2,-0.4 -0.927 26.7-122.8-118.6 139.5 70.7 41.1 31.7 59 68 A R - 0 0 190 -2,-0.4 16,-0.3 16,-0.2 2,-0.1 -0.791 25.5-130.6 -88.5 134.1 70.6 39.5 28.2 60 69 A L - 0 0 8 -2,-0.4 2,-0.3 -16,-0.3 14,-0.2 -0.333 16.8-165.2 -82.3 154.9 67.4 40.0 26.1 61 70 A H E -C 73 0A 60 12,-1.5 12,-1.2 -2,-0.1 2,-0.3 -0.725 12.5-141.0-126.0 170.0 65.4 37.4 24.3 62 71 A Q E +C 72 0A 75 -2,-0.3 10,-0.2 10,-0.2 8,-0.0 -0.985 19.7 176.2-143.9 128.0 62.8 38.0 21.7 63 72 A A E -C 71 0A 29 8,-2.2 8,-3.4 -2,-0.3 2,-0.1 -0.994 31.4-112.5-136.4 138.8 59.5 36.2 21.2 64 73 A P E -C 70 0A 114 0, 0.0 2,-0.4 0, 0.0 6,-0.2 -0.472 26.8-136.8 -72.9 141.4 56.6 36.7 18.8 65 74 A T > - 0 0 7 4,-3.0 3,-3.4 -2,-0.1 4,-0.4 -0.849 23.2-116.3 -94.2 138.1 53.3 37.8 20.3 66 75 A A T 3 S+ 0 0 90 -2,-0.4 -1,-0.1 1,-0.3 -58,-0.0 0.805 115.8 59.8 -42.6 -36.4 50.1 36.1 19.0 67 76 A R T 3 S- 0 0 140 1,-0.1 -1,-0.3 2,-0.0 3,-0.1 0.390 123.6-100.0 -74.3 -4.2 49.1 39.6 17.7 68 77 A G S < S+ 0 0 60 -3,-3.4 -33,-0.9 1,-0.4 2,-0.3 0.707 86.7 116.9 92.1 17.1 52.1 40.0 15.5 69 78 A A E -B 34 0A 21 -4,-0.4 -4,-3.0 -35,-0.2 -1,-0.4 -0.728 63.3-116.1-111.2 163.3 54.2 42.2 17.8 70 79 A V E -BC 33 64A 22 -37,-2.8 -37,-1.4 -2,-0.3 2,-0.5 -0.847 19.1-143.8-107.5 145.2 57.5 41.2 19.2 71 80 A R E -BC 32 63A 84 -8,-3.4 -8,-2.2 -2,-0.4 2,-0.5 -0.902 7.3-164.8-115.9 122.7 58.4 40.6 22.8 72 81 A F E +BC 31 62A 0 -41,-2.5 -41,-2.1 -2,-0.5 2,-0.2 -0.859 26.0 153.2-101.4 131.0 61.7 41.5 24.5 73 82 A W E -BC 30 61A 78 -12,-1.2 -12,-1.5 -2,-0.5 2,-0.2 -0.772 21.8-175.3-142.4-175.9 62.3 39.9 27.9 74 83 A b E -B 29 0A 2 -45,-0.8 -45,-1.9 -2,-0.2 2,-0.5 -0.790 20.6-135.1-179.7 142.5 65.0 38.7 30.3 75 84 A S E -B 28 0A 61 -16,-0.3 -47,-0.2 -2,-0.2 -16,-0.2 -0.967 26.9-119.6-117.5 123.3 64.9 37.0 33.6 76 85 A L - 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