==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 20-FEB-07 2EF4 . COMPND 2 MOLECULE: ARGINASE; . SOURCE 2 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS; . AUTHOR T.S.KUMAREVEL,P.KARTHE,S.KURAMITSU,S.YOKOYAMA,RIKEN STRUCTUR . 282 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11457.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 206 73.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 48 17.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 19 6.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 11.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 86 30.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 9 3.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 0 3 2 0 1 1 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 0 1 2 2 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 2 A E 0 0 163 0, 0.0 40,-2.3 0, 0.0 2,-0.4 0.000 360.0 360.0 360.0 -34.6 44.6 -4.9 -0.6 2 3 A R E -ab 41 80A 115 77,-0.8 79,-3.3 38,-0.2 2,-0.4 -0.875 360.0-176.8-105.7 135.0 46.6 -8.1 -0.3 3 4 A V E -ab 42 81A 5 38,-1.7 40,-1.7 -2,-0.4 2,-0.4 -0.976 8.6-160.8-129.4 141.1 45.6 -11.4 -1.7 4 5 A A E -ab 43 82A 4 77,-2.4 79,-3.0 -2,-0.4 2,-0.4 -0.978 6.4-157.7-122.9 135.3 47.3 -14.8 -1.5 5 6 A V E +ab 44 83A 0 38,-2.0 40,-3.3 -2,-0.4 41,-0.5 -0.944 15.3 170.4-116.0 135.2 46.5 -17.6 -3.8 6 7 A V E - b 0 84A 3 77,-2.1 79,-3.1 -2,-0.4 2,-0.3 -0.996 17.5-147.6-141.9 138.9 47.2 -21.3 -3.0 7 8 A G E -ab 47 85A 0 39,-2.5 41,-2.7 -2,-0.3 79,-0.2 -0.794 8.6-161.3-110.9 154.4 46.1 -24.4 -4.9 8 9 A V E - b 0 86A 1 77,-1.8 2,-2.8 -2,-0.3 79,-0.8 -0.806 7.8-163.0-132.6 86.8 45.2 -27.8 -3.6 9 10 A P + 0 0 36 0, 0.0 2,-0.5 0, 0.0 11,-0.2 -0.413 35.7 155.0 -71.1 70.0 45.5 -30.2 -6.7 10 11 A M + 0 0 2 -2,-2.8 78,-2.6 9,-0.3 12,-0.1 -0.894 24.2 158.8-111.7 131.3 43.5 -32.9 -4.9 11 12 A D + 0 0 1 -2,-0.5 2,-0.5 40,-0.3 42,-0.3 -0.555 25.5 149.7-144.7 67.1 41.4 -35.6 -6.5 12 13 A L + 0 0 0 4,-0.1 116,-0.3 40,-0.1 2,-0.3 -0.927 22.9 89.3-113.6 120.0 41.1 -38.2 -3.7 13 14 A G S S- 0 0 5 -2,-0.5 45,-0.1 113,-0.1 113,-0.0 -0.952 90.7 -45.5-177.2-167.8 38.1 -40.5 -3.5 14 15 A A S S- 0 0 55 -2,-0.3 2,-0.3 1,-0.1 44,-0.1 0.831 126.3 -3.7 -49.6 -36.3 36.5 -43.8 -4.6 15 16 A N S S- 0 0 126 38,-0.0 2,-0.1 -3,-0.0 -1,-0.1 -0.953 89.7 -90.7-150.8 161.6 37.7 -43.0 -8.1 16 17 A R - 0 0 115 -2,-0.3 -4,-0.1 38,-0.2 -5,-0.0 -0.434 28.9-177.4 -76.3 156.7 39.5 -40.1 -9.7 17 18 A R - 0 0 43 -2,-0.1 -1,-0.1 -6,-0.0 242,-0.1 0.457 46.1-112.9-126.6 -16.5 37.3 -37.3 -11.2 18 19 A G S > S+ 0 0 1 -7,-0.1 3,-1.4 241,-0.1 241,-0.3 0.476 76.9 127.0 94.9 5.2 40.1 -35.1 -12.6 19 20 A V G > + 0 0 0 1,-0.3 3,-2.1 238,-0.2 -9,-0.3 0.598 52.5 83.1 -73.2 -7.9 39.6 -32.1 -10.3 20 21 A D G 3 S+ 0 0 28 1,-0.3 4,-0.3 -11,-0.2 -1,-0.3 0.716 86.0 60.9 -66.1 -17.8 43.3 -32.1 -9.3 21 22 A M G <> S+ 0 0 82 -3,-1.4 4,-1.9 1,-0.2 -1,-0.3 0.431 78.0 95.9 -86.5 -0.2 43.8 -30.1 -12.5 22 23 A G H <> S+ 0 0 0 -3,-2.1 4,-2.6 234,-0.3 5,-0.2 0.912 77.7 53.0 -58.5 -47.3 41.5 -27.4 -11.2 23 24 A P H > S+ 0 0 1 0, 0.0 4,-2.5 0, 0.0 -1,-0.2 0.897 110.4 46.5 -57.9 -41.8 44.2 -25.1 -9.8 24 25 A S H > S+ 0 0 82 -4,-0.3 4,-2.0 2,-0.2 -2,-0.2 0.907 112.8 50.4 -65.5 -43.5 46.2 -25.0 -13.1 25 26 A A H X S+ 0 0 7 -4,-1.9 4,-1.2 2,-0.2 -1,-0.2 0.907 111.9 47.9 -60.6 -44.7 43.1 -24.4 -15.1 26 27 A L H ><>S+ 0 0 0 -4,-2.6 5,-1.0 2,-0.2 3,-0.6 0.921 112.6 47.4 -63.8 -45.1 42.1 -21.5 -12.8 27 28 A R H ><5S+ 0 0 61 -4,-2.5 3,-1.3 1,-0.2 -1,-0.2 0.849 108.1 58.7 -63.7 -30.6 45.6 -20.0 -12.9 28 29 A Y H 3<5S+ 0 0 180 -4,-2.0 -1,-0.2 1,-0.3 -2,-0.2 0.809 94.9 62.1 -67.2 -30.8 45.3 -20.5 -16.7 29 30 A A T <<5S- 0 0 6 -4,-1.2 -1,-0.3 -3,-0.6 -2,-0.2 0.158 120.8-111.4 -80.3 16.4 42.2 -18.3 -16.7 30 31 A R T <>5 + 0 0 158 -3,-1.3 4,-2.3 -5,-0.1 5,-0.2 0.829 58.9 160.6 56.4 43.4 44.5 -15.5 -15.5 31 32 A L H > S+ 0 0 38 2,-0.2 4,-2.0 1,-0.2 3,-0.3 0.948 111.6 48.3 -63.3 -51.9 46.3 -13.5 -10.7 33 34 A E H > S+ 0 0 86 1,-0.2 4,-2.3 2,-0.2 -1,-0.2 0.918 113.5 48.5 -56.2 -44.3 46.8 -11.0 -13.5 34 35 A Q H X S+ 0 0 53 -4,-2.3 4,-1.0 1,-0.2 -1,-0.2 0.786 107.2 55.1 -68.4 -28.1 43.1 -10.0 -13.3 35 36 A L H X>S+ 0 0 0 -4,-1.5 5,-2.1 -3,-0.3 4,-0.6 0.864 110.4 47.1 -70.9 -34.6 43.3 -9.5 -9.5 36 37 A E H ><5S+ 0 0 108 -4,-2.0 3,-1.4 1,-0.2 -2,-0.2 0.913 106.9 55.5 -70.3 -42.0 46.2 -7.2 -10.1 37 38 A D H 3<5S+ 0 0 124 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.783 104.4 57.4 -58.3 -26.9 44.3 -5.3 -12.9 38 39 A L H 3<5S- 0 0 56 -4,-1.0 -1,-0.3 -5,-0.2 -2,-0.2 0.724 128.7 -98.7 -76.8 -24.3 41.7 -4.9 -10.1 39 40 A G T <<5S+ 0 0 61 -3,-1.4 2,-0.3 -4,-0.6 -3,-0.2 0.444 79.7 129.2 119.5 3.5 44.2 -3.1 -7.9 40 41 A Y < - 0 0 60 -5,-2.1 2,-0.7 -38,-0.0 -1,-0.4 -0.631 56.9-131.4 -90.2 146.4 45.3 -5.9 -5.6 41 42 A T E -a 2 0A 70 -40,-2.3 -38,-1.7 -2,-0.3 2,-0.3 -0.893 38.6-163.9 -96.1 120.0 48.9 -6.8 -4.9 42 43 A V E -a 3 0A 23 -2,-0.7 2,-0.4 -40,-0.2 -38,-0.2 -0.833 22.5-172.1-114.5 145.3 49.0 -10.5 -5.3 43 44 A E E -a 4 0A 126 -40,-1.7 -38,-2.0 -2,-0.3 2,-0.7 -0.991 17.9-143.9-133.5 125.6 51.3 -13.4 -4.4 44 45 A D E -a 5 0A 54 -2,-0.4 -38,-0.2 -40,-0.2 3,-0.1 -0.804 8.9-166.5 -89.3 118.0 50.9 -16.9 -5.6 45 46 A L E - 0 0 29 -40,-3.3 2,-0.2 -2,-0.7 -39,-0.2 0.461 34.9-132.2 -83.0 -1.7 52.0 -19.2 -2.7 46 47 A G E - 0 0 26 -41,-0.5 -39,-2.5 2,-0.0 2,-0.3 -0.562 41.3 -34.3 88.4-152.1 52.0 -22.2 -5.0 47 48 A D E -a 7 0A 82 -41,-0.2 -39,-0.2 -2,-0.2 -41,-0.0 -0.828 46.6-119.9-116.4 151.8 50.4 -25.6 -4.3 48 49 A V - 0 0 6 -41,-2.7 2,-0.1 -2,-0.3 17,-0.1 -0.711 44.0-105.4 -83.9 131.7 49.9 -27.7 -1.2 49 50 A P - 0 0 104 0, 0.0 2,-0.4 0, 0.0 19,-0.1 -0.383 46.2-174.7 -58.8 128.6 51.6 -31.1 -1.6 50 51 A V - 0 0 34 -2,-0.1 2,-0.1 -41,-0.1 12,-0.1 -0.995 24.4-128.8-133.2 134.3 49.0 -33.7 -2.2 51 52 A S - 0 0 50 -2,-0.4 -40,-0.3 10,-0.3 2,-0.2 -0.392 30.0-143.0 -69.9 148.1 49.3 -37.5 -2.5 52 53 A L - 0 0 88 -42,-0.1 2,-0.3 -2,-0.1 -40,-0.1 -0.711 7.3-125.7-110.3 172.1 47.6 -38.9 -5.7 53 54 A A 0 0 18 -42,-0.3 -37,-0.0 -2,-0.2 -38,-0.0 -0.838 360.0 360.0-114.7 149.2 45.7 -42.0 -6.2 54 55 A R 0 0 140 -2,-0.3 -38,-0.2 -39,-0.0 -1,-0.2 0.460 360.0 360.0-102.5 360.0 46.2 -44.8 -8.7 55 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 56 64 A L > 0 0 87 0, 0.0 3,-1.3 0, 0.0 70,-0.1 0.000 360.0 360.0 360.0 49.5 36.4 -43.8 3.3 57 65 A A T 3 - 0 0 41 1,-0.2 70,-0.3 2,-0.1 -43,-0.1 -0.277 360.0 -0.8 -62.0 135.4 39.3 -43.9 0.8 58 66 A Y T 3> S+ 0 0 72 1,-0.1 4,-3.1 3,-0.1 5,-0.3 0.690 78.7 147.2 60.7 24.3 42.4 -41.6 1.4 59 67 A L H <> S+ 0 0 15 -3,-1.3 4,-3.2 1,-0.2 5,-0.2 0.938 74.8 44.6 -54.8 -49.3 40.9 -40.1 4.6 60 68 A E H > S+ 0 0 78 1,-0.2 4,-2.6 2,-0.2 -1,-0.2 0.895 115.0 47.9 -63.7 -39.2 44.4 -39.8 6.1 61 69 A E H > S+ 0 0 79 2,-0.2 4,-1.8 1,-0.2 -10,-0.3 0.870 115.3 45.1 -69.6 -35.7 45.9 -38.4 2.9 62 70 A I H X S+ 0 0 1 -4,-3.1 4,-2.6 2,-0.2 5,-0.2 0.925 114.2 49.6 -70.2 -45.1 43.0 -35.9 2.5 63 71 A R H X S+ 0 0 33 -4,-3.2 4,-1.7 -5,-0.3 -2,-0.2 0.886 110.5 51.8 -58.3 -41.8 43.3 -35.1 6.2 64 72 A A H X S+ 0 0 47 -4,-2.6 4,-1.7 2,-0.2 -1,-0.2 0.878 111.8 44.2 -65.3 -42.4 47.1 -34.6 5.8 65 73 A A H X S+ 0 0 5 -4,-1.8 4,-2.3 2,-0.2 -2,-0.2 0.900 113.2 50.7 -70.2 -41.7 46.8 -32.2 2.9 66 74 A A H X S+ 0 0 2 -4,-2.6 4,-2.7 1,-0.2 -2,-0.2 0.829 108.9 53.9 -65.2 -31.3 44.0 -30.2 4.5 67 75 A L H X S+ 0 0 54 -4,-1.7 4,-2.6 -5,-0.2 5,-0.2 0.920 107.5 48.2 -68.8 -46.3 46.1 -29.9 7.6 68 76 A V H X S+ 0 0 71 -4,-1.7 4,-2.0 1,-0.2 -2,-0.2 0.914 114.4 48.8 -60.3 -41.5 49.1 -28.4 5.7 69 77 A L H X S+ 0 0 0 -4,-2.3 4,-2.4 2,-0.2 5,-0.2 0.925 110.1 49.6 -63.2 -47.1 46.6 -26.1 4.0 70 78 A K H X S+ 0 0 49 -4,-2.7 4,-2.3 1,-0.2 -2,-0.2 0.937 112.7 47.2 -58.3 -49.1 45.0 -25.0 7.4 71 79 A E H X S+ 0 0 110 -4,-2.6 4,-1.1 1,-0.2 -1,-0.2 0.876 110.9 53.1 -60.3 -39.8 48.4 -24.3 8.9 72 80 A R H < S+ 0 0 117 -4,-2.0 4,-0.4 -5,-0.2 3,-0.4 0.929 113.1 41.4 -63.0 -47.6 49.5 -22.4 5.9 73 81 A L H >< S+ 0 0 1 -4,-2.4 3,-0.9 1,-0.2 -2,-0.2 0.832 108.6 59.6 -71.8 -32.3 46.4 -20.0 5.9 74 82 A A H 3< S+ 0 0 46 -4,-2.3 -1,-0.2 -5,-0.2 -2,-0.2 0.786 103.8 54.7 -65.5 -25.0 46.5 -19.6 9.7 75 83 A A T 3< S+ 0 0 80 -4,-1.1 -1,-0.2 -3,-0.4 -2,-0.2 0.603 80.8 109.5 -85.7 -13.9 50.0 -18.2 9.3 76 84 A L S < S- 0 0 18 -3,-0.9 4,-0.1 -4,-0.4 3,-0.1 -0.371 81.0-100.9 -64.2 140.8 49.1 -15.5 6.8 77 85 A P > - 0 0 70 0, 0.0 3,-1.4 0, 0.0 -1,-0.1 -0.223 44.5 -97.7 -58.1 150.4 49.3 -11.9 8.2 78 86 A E T 3 S+ 0 0 147 1,-0.2 3,-0.1 -3,-0.1 -3,-0.0 -0.431 113.0 45.7 -67.3 148.6 46.0 -10.5 9.1 79 87 A G T 3 S+ 0 0 59 1,-0.3 -77,-0.8 -3,-0.1 2,-0.6 0.348 84.3 117.6 98.1 -8.7 44.7 -8.3 6.3 80 88 A V E < -b 2 0A 13 -3,-1.4 -1,-0.3 -79,-0.1 -77,-0.2 -0.849 58.0-146.0 -96.9 123.0 45.7 -10.8 3.7 81 89 A F E -b 3 0A 29 -79,-3.3 -77,-2.4 -2,-0.6 2,-0.3 -0.785 18.1-148.7 -88.8 115.9 42.7 -12.1 1.7 82 90 A P E -b 4 0A 1 0, 0.0 169,-2.3 0, 0.0 2,-0.5 -0.671 13.7-168.4 -92.8 140.4 43.2 -15.8 0.9 83 91 A I E -bc 5 251A 0 -79,-3.0 -77,-2.1 -2,-0.3 2,-0.6 -0.964 8.0-160.7-125.3 110.9 41.9 -17.6 -2.2 84 92 A V E -bc 6 252A 1 167,-2.6 169,-2.9 -2,-0.5 2,-0.3 -0.836 6.2-160.4 -96.8 119.3 42.2 -21.3 -2.2 85 93 A L E +bc 7 253A 0 -79,-3.1 -77,-1.8 -2,-0.6 2,-0.3 -0.715 28.1 139.7 -94.5 146.6 42.0 -22.9 -5.7 86 94 A G E -b 8 0A 0 167,-2.4 170,-1.0 -2,-0.3 2,-0.1 -0.857 54.5-127.6-161.5-166.6 41.2 -26.5 -5.9 87 95 A G S S+ 0 0 0 -79,-0.8 168,-2.5 1,-0.4 -76,-0.2 0.155 88.1 43.7-122.2-115.3 39.8 -29.8 -7.0 88 96 A D S > S- 0 0 0 -78,-2.6 3,-1.7 1,-0.2 -1,-0.4 0.063 71.1-136.9 -39.6 131.2 38.1 -31.8 -4.1 89 97 A H G > S+ 0 0 0 1,-0.3 3,-1.7 39,-0.2 4,-0.2 0.602 93.3 89.1 -68.4 -7.5 35.8 -29.7 -1.9 90 98 A S G > S+ 0 0 0 1,-0.3 3,-1.8 2,-0.2 4,-0.5 0.780 70.7 73.3 -58.6 -27.7 37.4 -31.6 0.9 91 99 A L G X> S+ 0 0 1 -3,-1.7 4,-2.3 1,-0.3 3,-1.5 0.792 77.7 74.7 -59.6 -28.9 40.0 -28.9 1.0 92 100 A S H <>>S+ 0 0 0 -3,-1.7 4,-2.2 1,-0.3 5,-0.5 0.737 81.3 69.7 -60.2 -19.9 37.6 -26.5 2.6 93 101 A M H <>5S+ 0 0 0 -3,-1.8 4,-1.1 -4,-0.2 -1,-0.3 0.938 111.6 33.5 -60.2 -40.3 38.0 -28.4 5.9 94 102 A G H <>5S+ 0 0 0 -3,-1.5 4,-1.9 -4,-0.5 -2,-0.2 0.881 118.7 49.9 -82.0 -42.0 41.4 -26.9 5.8 95 103 A S H X5S+ 0 0 0 -4,-2.3 4,-3.4 2,-0.2 5,-0.3 0.937 114.9 43.0 -64.9 -47.5 40.7 -23.5 4.2 96 104 A V H X5S+ 0 0 1 -4,-2.2 4,-1.4 1,-0.2 -1,-0.2 0.947 117.3 45.8 -63.9 -47.5 37.8 -22.6 6.5 97 105 A A H <5S+ 0 0 0 -4,-1.9 3,-0.8 2,-0.2 -2,-0.2 0.917 114.8 46.3 -82.5 -46.8 42.7 -22.0 8.6 99 107 A A H 3<5S+ 0 0 1 -4,-3.4 -2,-0.2 1,-0.2 -3,-0.2 0.667 103.3 66.8 -70.3 -16.7 41.3 -18.7 7.2 100 108 A A T ><5S- 0 0 2 -4,-1.4 3,-2.0 -5,-0.3 -1,-0.2 0.812 85.1-158.0 -73.9 -28.5 39.1 -18.4 10.3 101 109 A R T < 5 - 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0 0 30 -4,-1.2 4,-1.4 -5,-0.6 5,-0.1 -0.060 32.5 -85.5 92.8 157.6 15.6 -14.7 -6.7 189 197 A V H > S+ 0 0 7 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.788 121.8 63.0 -73.5 -26.4 19.3 -14.5 -5.8 190 198 A A H > S+ 0 0 36 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.955 107.8 40.3 -62.9 -51.1 19.2 -10.9 -4.7 191 199 A R H > S+ 0 0 130 -4,-0.5 4,-2.4 2,-0.2 -1,-0.2 0.872 116.4 51.1 -65.2 -38.4 16.7 -11.5 -1.8 192 200 A I H X S+ 0 0 0 -4,-1.4 4,-1.8 2,-0.2 -1,-0.2 0.910 108.6 51.9 -65.3 -40.4 18.5 -14.7 -0.9 193 201 A A H X S+ 0 0 0 -4,-2.7 4,-2.3 1,-0.2 -2,-0.2 0.905 110.4 48.7 -61.4 -41.0 21.8 -12.9 -0.8 194 202 A E H X S+ 0 0 110 -4,-2.0 4,-2.2 1,-0.2 -2,-0.2 0.906 110.9 49.5 -64.8 -43.1 20.3 -10.3 1.5 195 203 A E H X S+ 0 0 45 -4,-2.4 4,-2.7 2,-0.2 -1,-0.2 0.780 108.8 54.6 -66.1 -28.5 18.9 -13.0 3.8 196 204 A V H X S+ 0 0 0 -4,-1.8 4,-1.5 2,-0.2 -2,-0.2 0.958 110.0 44.7 -68.4 -51.6 22.4 -14.6 3.8 197 205 A L H < S+ 0 0 22 -4,-2.3 6,-0.2 1,-0.2 -2,-0.2 0.867 117.0 46.7 -59.8 -38.0 24.0 -11.4 5.0 198 206 A K H >< S+ 0 0 137 -4,-2.2 3,-1.9 1,-0.2 -2,-0.2 0.937 108.9 52.8 -71.2 -47.6 21.3 -10.9 7.6 199 207 A H H 3< S+ 0 0 61 -4,-2.7 -1,-0.2 1,-0.3 -2,-0.2 0.779 122.3 33.1 -58.9 -27.2 21.3 -14.5 8.8 200 208 A L T >< S+ 0 0 2 -4,-1.5 3,-1.5 -5,-0.1 -1,-0.3 -0.032 89.7 160.6-118.5 31.1 25.1 -14.1 9.3 201 209 A Q T < + 0 0 122 -3,-1.9 -3,-0.1 1,-0.2 -4,-0.0 -0.159 61.6 19.3 -61.1 142.9 25.2 -10.4 10.2 202 210 A G T 3 S+ 0 0 69 1,-0.2 -1,-0.2 -5,-0.1 -4,-0.1 0.451 100.6 115.4 79.8 2.3 28.2 -8.9 12.0 203 211 A L S < S- 0 0 17 -3,-1.5 -1,-0.2 -6,-0.2 -98,-0.2 -0.757 72.2-113.4-109.3 149.1 30.4 -11.8 11.0 204 212 A P - 0 0 39 0, 0.0 -98,-3.3 0, 0.0 2,-0.5 -0.541 44.1-130.0 -70.9 148.0 33.5 -12.0 8.8 205 213 A L E -dg 106 248A 0 42,-3.5 44,-3.9 -100,-0.2 45,-1.3 -0.899 22.9-169.2-114.3 130.9 32.5 -14.1 5.7 206 214 A H E -dg 107 250A 2 -100,-3.1 -98,-2.6 -2,-0.5 2,-0.6 -0.954 14.8-156.4-110.8 119.4 34.2 -17.1 4.1 207 215 A V E -dg 108 251A 0 43,-2.5 45,-2.5 -2,-0.6 2,-0.7 -0.872 6.4-167.2-101.5 123.3 32.7 -18.0 0.7 208 216 A S E -dg 109 252A 0 -100,-2.5 -98,-2.4 -2,-0.6 2,-0.7 -0.915 10.6-168.1-110.2 105.4 33.2 -21.6 -0.5 209 217 A L E -dg 110 253A 1 43,-2.3 45,-2.1 -2,-0.7 2,-0.5 -0.844 6.5-164.3-103.1 111.4 32.3 -21.7 -4.2 210 218 A D E > - g 0 254A 2 -100,-2.9 3,-2.1 -2,-0.7 4,-0.3 -0.814 20.2-138.1 -91.8 127.9 31.9 -25.1 -5.9 211 219 A A G > S+ 0 0 0 43,-2.1 3,-1.5 -2,-0.5 -1,-0.1 0.782 97.7 70.3 -54.6 -30.4 31.9 -24.9 -9.7 212 220 A D G 3 S+ 0 0 2 1,-0.3 14,-0.3 42,-0.1 -1,-0.3 0.527 76.1 79.7 -68.9 -5.9 29.0 -27.4 -9.9 213 221 A V G < S+ 0 0 0 -3,-2.1 17,-2.2 -103,-0.3 -1,-0.3 0.848 81.7 82.2 -68.9 -29.4 26.6 -24.9 -8.5 214 222 A L B < S-i 230 0C 1 -3,-1.5 12,-0.3 -4,-0.3 17,-0.2 -0.431 104.5 -91.2 -73.2 146.4 26.5 -23.5 -12.0 215 223 A D >> - 0 0 36 15,-2.5 4,-2.5 1,-0.2 3,-1.4 -0.385 32.6-134.1 -58.4 128.3 24.3 -25.2 -14.6 216 224 A P T 34 S+ 0 0 27 0, 0.0 -1,-0.2 0, 0.0 6,-0.1 0.652 103.7 65.6 -61.0 -15.4 26.4 -27.9 -16.3 217 225 A T T 34 S+ 0 0 114 2,-0.2 -2,-0.1 1,-0.1 -3,-0.0 0.837 114.6 31.5 -72.8 -33.0 25.1 -26.7 -19.7 218 226 A L T <4 S+ 0 0 59 -3,-1.4 -1,-0.1 1,-0.2 -3,-0.1 0.794 135.2 27.7 -91.5 -35.9 26.9 -23.5 -19.1 219 227 A A < + 0 0 0 -4,-2.5 -1,-0.2 1,-0.1 -2,-0.2 -0.683 65.3 163.1-132.6 79.0 29.8 -24.8 -17.0 220 228 A P + 0 0 30 0, 0.0 2,-2.2 0, 0.0 41,-0.2 0.744 53.8 87.7 -67.5 -29.7 30.5 -28.5 -17.9 221 229 A G + 0 0 0 39,-0.1 36,-3.1 41,-0.1 2,-0.3 -0.382 63.1 119.8 -76.3 67.6 34.0 -28.8 -16.4 222 230 A V B -J 256 0D 1 -2,-2.2 34,-0.2 34,-0.3 33,-0.1 -0.919 69.6-118.6-130.5 156.6 33.1 -29.8 -12.8 223 231 A G S S+ 0 0 9 32,-1.8 -1,-0.1 -2,-0.3 33,-0.1 0.915 106.8 13.1 -56.6 -49.4 33.9 -32.8 -10.6 224 232 A T S S- 0 0 52 31,-0.1 -1,-0.3 -3,-0.1 2,-0.1 -0.827 82.5-151.1-134.7 93.5 30.2 -33.9 -10.2 225 233 A P - 0 0 64 0, 0.0 -10,-0.1 0, 0.0 -13,-0.1 -0.370 11.7-172.3 -66.6 139.9 27.8 -32.2 -12.6 226 234 A V - 0 0 17 -14,-0.3 3,-0.1 -12,-0.3 -64,-0.0 -0.972 23.9-119.6-137.7 119.0 24.2 -31.7 -11.6 227 235 A P S S+ 0 0 104 0, 0.0 -12,-0.1 0, 0.0 -13,-0.0 -0.169 84.0 28.8 -59.5 145.6 21.5 -30.4 -14.0 228 236 A G S S+ 0 0 44 1,-0.1 -13,-0.1 2,-0.1 3,-0.1 0.947 79.0 146.8 73.3 54.9 19.6 -27.2 -13.5 229 237 A G - 0 0 9 1,-0.2 -15,-0.2 -3,-0.1 -14,-0.1 -0.181 51.2 -49.0-104.5-161.6 21.8 -24.8 -11.5 230 238 A L B -i 214 0C 0 -17,-2.2 -15,-2.5 -71,-0.1 -1,-0.2 -0.327 52.6-123.9 -68.7 151.6 22.5 -21.1 -11.3 231 239 A T > - 0 0 64 -17,-0.2 4,-1.9 1,-0.1 5,-0.2 -0.410 29.9-106.0 -85.1 172.6 23.1 -19.1 -14.4 232 240 A Y H > S+ 0 0 64 1,-0.2 4,-1.6 2,-0.2 -1,-0.1 0.872 120.7 51.1 -68.8 -37.7 26.4 -17.2 -14.7 233 241 A R H > S+ 0 0 212 2,-0.2 4,-2.6 1,-0.2 5,-0.2 0.898 108.8 53.2 -66.5 -39.0 24.6 -13.8 -14.1 234 242 A E H > S+ 0 0 54 1,-0.2 4,-2.3 2,-0.2 -2,-0.2 0.941 108.6 46.9 -61.1 -49.9 22.9 -15.2 -11.0 235 243 A A H X S+ 0 0 0 -4,-1.9 4,-2.0 1,-0.2 -1,-0.2 0.851 113.0 53.4 -59.8 -33.9 26.2 -16.4 -9.4 236 244 A H H X S+ 0 0 33 -4,-1.6 4,-2.6 2,-0.2 -2,-0.2 0.942 106.4 48.5 -64.8 -52.1 27.6 -13.0 -10.3 237 245 A L H X S+ 0 0 72 -4,-2.6 4,-2.5 1,-0.2 5,-0.2 0.888 109.8 54.9 -57.1 -41.3 24.8 -11.0 -8.6 238 246 A L H X S+ 0 0 0 -4,-2.3 4,-2.0 1,-0.2 -1,-0.2 0.945 110.2 44.7 -57.3 -49.5 25.3 -13.2 -5.6 239 247 A M H X S+ 0 0 1 -4,-2.0 4,-2.4 2,-0.2 -2,-0.2 0.865 111.7 53.7 -62.7 -40.0 29.0 -12.4 -5.4 240 248 A E H X S+ 0 0 43 -4,-2.6 4,-2.4 2,-0.2 -2,-0.2 0.946 109.8 46.0 -61.0 -51.0 28.4 -8.7 -6.0 241 249 A I H X S+ 0 0 17 -4,-2.5 4,-1.0 1,-0.2 -1,-0.2 0.887 113.9 48.2 -62.2 -39.4 25.9 -8.4 -3.1 242 250 A L H >X>S+ 0 0 0 -4,-2.0 5,-0.6 -5,-0.2 4,-0.6 0.902 110.3 53.7 -66.7 -38.4 28.2 -10.3 -0.7 243 251 A A H ><5S+ 0 0 26 -4,-2.4 3,-1.6 1,-0.2 -2,-0.2 0.906 102.1 58.4 -60.3 -42.5 31.0 -8.0 -1.9 244 252 A E H 3<5S+ 0 0 132 -4,-2.4 -1,-0.2 1,-0.3 -2,-0.2 0.796 92.5 67.5 -58.9 -30.5 28.9 -5.0 -1.0 245 253 A S H <<5S- 0 0 35 -4,-1.0 -1,-0.3 -3,-0.6 -2,-0.2 0.801 94.5-144.6 -60.7 -27.6 28.6 -6.2 2.6 246 254 A G T <<5S+ 0 0 68 -3,-1.6 -3,-0.1 -4,-0.6 -1,-0.1 0.599 73.8 102.7 71.7 10.9 32.4 -5.5 2.9 247 255 A R < + 0 0 60 -5,-0.6 -42,-3.5 -43,-0.1 2,-0.3 0.484 38.4 115.6-105.2 -3.8 32.5 -8.6 5.2 248 256 A V E + g 0 205A 22 -6,-0.4 -42,-0.2 -44,-0.2 3,-0.1 -0.519 31.1 169.7 -69.4 127.2 34.0 -11.3 2.9 249 257 A Q E + 0 0 27 -44,-3.9 2,-0.3 -2,-0.3 -43,-0.2 0.519 57.3 11.5-117.5 -10.0 37.4 -12.4 4.2 250 258 A S E - g 0 206A 1 -45,-1.3 -43,-2.5 -169,-0.2 2,-0.3 -0.984 58.0-154.2-164.6 160.3 38.3 -15.5 2.3 251 259 A L E -cg 83 207A 0 -169,-2.3 -167,-2.6 -2,-0.3 2,-0.4 -0.999 6.7-157.5-149.2 141.5 37.3 -17.6 -0.7 252 260 A D E -cg 84 208A 0 -45,-2.5 -43,-2.3 -2,-0.3 2,-0.5 -0.946 3.9-170.5-114.2 136.9 37.5 -21.1 -2.1 253 261 A L E +cg 85 209A 0 -169,-2.9 -167,-2.4 -2,-0.4 2,-0.2 -0.908 33.3 160.2-126.7 97.5 37.2 -21.8 -5.9 254 262 A V E + g 0 210A 0 -45,-2.1 -43,-2.1 -2,-0.5 -167,-0.2 -0.638 31.2 38.0-122.1 175.2 36.9 -25.6 -6.1 255 263 A E + 0 0 4 -168,-2.5 -32,-1.8 1,-0.2 2,-0.3 0.617 59.4 161.0 62.5 21.9 35.9 -28.6 -8.1 256 264 A V B -J 222 0D 0 -170,-1.0 -234,-0.3 -237,-0.2 -34,-0.3 -0.575 19.8-166.6 -72.4 131.6 37.1 -27.4 -11.5 257 265 A N >> - 0 0 3 -36,-3.1 3,-1.5 -2,-0.3 4,-1.0 -0.811 12.2-174.3-126.0 89.4 37.4 -30.4 -13.8 258 266 A P T 34 S+ 0 0 32 0, 0.0 6,-0.2 0, 0.0 5,-0.1 0.763 79.9 69.5 -51.7 -32.2 39.3 -29.6 -17.1 259 267 A I T 34 S+ 0 0 112 -241,-0.3 -241,-0.1 1,-0.2 -38,-0.1 0.861 110.3 31.1 -58.0 -38.3 38.6 -33.0 -18.5 260 268 A L T <4 S+ 0 0 91 -3,-1.5 -1,-0.2 -40,-0.1 -39,-0.1 0.542 101.8 106.9 -97.0 -10.5 34.9 -32.3 -18.9 261 269 A D < - 0 0 17 -4,-1.0 2,-0.6 -41,-0.2 -42,-0.1 -0.139 66.8-131.6 -68.5 163.5 35.4 -28.6 -19.6 262 270 A E S > S- 0 0 100 1,-0.1 3,-1.5 -41,-0.0 -41,-0.1 -0.919 83.2 -31.8-119.1 100.9 35.0 -26.8 -22.9 263 271 A R T 3 S- 0 0 214 -2,-0.6 -1,-0.1 1,-0.3 -2,-0.0 0.850 109.6 -68.7 56.4 38.1 38.0 -24.6 -23.6 264 272 A N T 3> S+ 0 0 23 -6,-0.2 4,-1.9 1,-0.1 -1,-0.3 0.670 94.1 140.1 60.0 20.7 38.5 -23.8 -19.9 265 273 A R H <> + 0 0 95 -3,-1.5 4,-1.9 1,-0.2 -2,-0.1 0.817 67.9 53.1 -66.7 -29.6 35.2 -21.8 -19.8 266 274 A T H > S+ 0 0 0 2,-0.2 4,-2.0 1,-0.2 -1,-0.2 0.886 109.5 48.5 -70.6 -38.7 34.2 -23.2 -16.4 267 275 A A H > S+ 0 0 0 1,-0.2 4,-1.8 2,-0.2 -2,-0.2 0.875 111.4 51.5 -68.0 -35.3 37.6 -22.1 -14.9 268 276 A E H X S+ 0 0 104 -4,-1.9 4,-2.4 2,-0.2 -2,-0.2 0.863 107.0 53.1 -68.6 -37.0 37.1 -18.7 -16.5 269 277 A M H X S+ 0 0 16 -4,-1.9 4,-2.7 2,-0.2 -2,-0.2 0.920 109.0 48.2 -65.8 -43.2 33.6 -18.3 -15.0 270 278 A L H X S+ 0 0 0 -4,-2.0 4,-2.3 2,-0.2 -1,-0.2 0.882 110.7 51.6 -65.6 -36.0 34.9 -19.0 -11.5 271 279 A V H X S+ 0 0 1 -4,-1.8 4,-2.0 2,-0.2 -1,-0.2 0.938 110.8 48.8 -64.3 -42.6 37.7 -16.5 -12.0 272 280 A G H X S+ 0 0 13 -4,-2.4 4,-1.9 1,-0.2 -2,-0.2 0.907 110.4 51.0 -61.0 -41.9 35.1 -14.0 -13.1 273 281 A L H X S+ 0 0 0 -4,-2.7 4,-2.2 1,-0.2 -1,-0.2 0.874 107.7 53.3 -63.4 -37.3 33.0 -14.8 -10.0 274 282 A A H X S+ 0 0 0 -4,-2.3 4,-1.5 1,-0.2 -1,-0.2 0.882 105.9 53.3 -65.9 -38.7 36.0 -14.3 -7.8 275 283 A L H <>S+ 0 0 2 -4,-2.0 5,-2.6 2,-0.2 3,-0.2 0.934 108.9 48.6 -63.8 -43.3 36.6 -10.9 -9.3 276 284 A S H ><5S+ 0 0 5 -4,-1.9 3,-2.1 1,-0.3 -1,-0.2 0.912 108.1 54.2 -62.0 -41.5 33.0 -9.8 -8.6 277 285 A L H 3<5S+ 0 0 6 -4,-2.2 -1,-0.3 1,-0.3 -2,-0.2 0.835 109.5 50.2 -61.8 -27.8 33.3 -11.1 -5.0 278 286 A L T 3<5S- 0 0 13 -4,-1.5 -1,-0.3 -3,-0.2 -2,-0.2 0.257 132.9 -88.9 -95.2 14.0 36.4 -8.9 -4.8 279 287 A G T < 5 + 0 0 45 -3,-2.1 2,-0.4 1,-0.3 -3,-0.2 0.598 68.8 155.5 97.1 11.0 34.6 -5.8 -6.1 280 288 A K < + 0 0 94 -5,-2.6 2,-0.3 -6,-0.1 -1,-0.3 -0.589 17.9 179.7 -75.5 130.4 34.9 -5.9 -9.9 281 289 A R - 0 0 136 -2,-0.4 -5,-0.0 1,-0.1 -6,-0.0 -0.887 40.4-118.0-125.8 157.6 32.1 -4.0 -11.5 282 290 A I 0 0 175 -2,-0.3 -1,-0.1 1,-0.3 -2,-0.0 0.928 360.0 360.0 -60.9 -43.2 31.3 -3.4 -15.2 283 291 A F 0 0 253 -3,-0.1 -1,-0.3 0, 0.0 -3,-0.0 -0.304 360.0 360.0 -93.4 360.0 31.7 0.4 -14.6