==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=27-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 24-MAR-00 1EOU . COMPND 2 MOLECULE: CARBONIC ANHYDRASE II (CA II); . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR R.RECACHA,M.J.COSTANZO,B.E.MARYANOFF,D.CHATTOPADHYAY . 258 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 11905.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 168 65.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 18 7.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 58 22.5 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 26 10.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 35 13.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 17 6.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 1 0 2 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 3 A H 0 0 149 0, 0.0 3,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 84.1 9.9 0.9 5.5 2 4 A H - 0 0 140 1,-0.3 0, 0.0 7,-0.0 0, 0.0 0.463 360.0 -4.9 -95.5-123.6 9.6 1.2 9.3 3 5 A W + 0 0 59 1,-0.1 -1,-0.3 11,-0.1 2,-0.2 -0.196 65.3 154.6 -69.8 163.5 7.8 -1.1 11.7 4 6 A G - 0 0 11 5,-2.8 10,-0.1 2,-0.1 -1,-0.1 -0.772 53.1 -89.8-161.4-153.9 5.7 -4.1 10.6 5 7 A Y S S+ 0 0 36 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.243 82.6 107.1-122.1 12.2 4.5 -7.4 11.8 6 8 A G S > S- 0 0 41 4,-0.1 4,-1.4 1,-0.1 3,-0.3 -0.109 86.3 -92.9 -82.1-176.5 7.3 -9.6 10.7 7 9 A K T 4 S+ 0 0 180 1,-0.2 5,-0.1 2,-0.2 -1,-0.1 0.892 123.7 37.7 -63.7 -40.6 10.1 -11.4 12.6 8 10 A H T 4 S+ 0 0 162 1,-0.2 -1,-0.2 5,-0.0 -3,-0.0 0.514 131.2 24.1 -93.9 -5.5 12.5 -8.5 12.1 9 11 A N T 4 S+ 0 0 60 -3,-0.3 -5,-2.8 -6,-0.1 -2,-0.2 0.248 94.1 115.5-141.2 12.2 10.2 -5.5 12.5 10 12 A G S >X S- 0 0 3 -4,-1.4 3,-2.9 -5,-0.2 4,-1.0 0.027 84.9 -63.1 -76.5-172.1 7.3 -6.8 14.5 11 13 A P T 34 S+ 0 0 27 0, 0.0 4,-0.5 0, 0.0 -6,-0.1 0.694 129.0 58.8 -41.9 -35.8 5.9 -5.8 18.0 12 14 A E T 34 S+ 0 0 146 1,-0.2 4,-0.1 2,-0.1 -5,-0.0 0.607 109.9 45.5 -76.4 -9.2 9.0 -7.0 19.9 13 15 A H T X4 S+ 0 0 57 -3,-2.9 3,-1.9 1,-0.1 4,-0.4 0.697 89.3 85.3-101.4 -27.1 11.1 -4.5 17.9 14 16 A W G >X S+ 0 0 7 -4,-1.0 4,-2.4 1,-0.3 3,-0.9 0.757 73.6 71.2 -47.4 -38.6 8.9 -1.5 18.1 15 17 A H G 34 S+ 0 0 71 -4,-0.5 -1,-0.3 1,-0.2 6,-0.1 0.803 86.6 69.0 -53.7 -30.0 10.2 -0.2 21.4 16 18 A K G <4 S+ 0 0 124 -3,-1.9 -1,-0.2 1,-0.2 -2,-0.2 0.918 115.6 22.4 -57.8 -46.9 13.5 0.8 19.7 17 19 A D T <4 S+ 0 0 111 -3,-0.9 -1,-0.2 -4,-0.4 -2,-0.2 0.700 135.1 40.8 -91.4 -21.5 11.9 3.6 17.7 18 20 A F >< - 0 0 48 -4,-2.4 3,-2.4 1,-0.1 -1,-0.2 -0.735 63.2-179.6-131.3 82.1 9.0 4.0 20.1 19 21 A P G > S+ 0 0 102 0, 0.0 3,-2.1 0, 0.0 -1,-0.1 0.763 77.3 73.7 -49.9 -33.1 10.1 3.7 23.8 20 22 A I G > S+ 0 0 63 1,-0.3 3,-2.8 2,-0.2 -5,-0.1 0.695 71.9 88.8 -58.7 -16.3 6.5 4.3 25.0 21 23 A A G < S+ 0 0 6 -3,-2.4 -1,-0.3 1,-0.3 -6,-0.1 0.770 90.9 45.5 -53.1 -25.7 5.9 0.7 23.7 22 24 A K G < S+ 0 0 143 -3,-2.1 -1,-0.3 -4,-0.1 -2,-0.2 -0.044 96.1 130.6-107.3 29.4 7.0 -0.4 27.2 23 25 A G S < S- 0 0 11 -3,-2.8 3,-0.4 1,-0.1 -3,-0.0 0.115 72.0 -98.6 -75.4-171.4 4.8 2.2 29.0 24 26 A E S S+ 0 0 120 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.591 113.9 34.5 -86.2 -14.1 2.3 2.2 31.8 25 27 A R S S+ 0 0 48 224,-0.1 -1,-0.2 168,-0.1 2,-0.2 -0.280 79.3 154.8-140.2 59.7 -0.8 2.1 29.8 26 28 A Q - 0 0 3 -3,-0.4 220,-0.2 221,-0.4 170,-0.1 -0.523 32.8 -99.0 -90.2 152.4 -0.2 0.1 26.6 27 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.2 -2,-0.0 -0.888 78.7 35.7-125.6 154.0 -2.8 -1.8 24.5 28 30 A P + 0 0 0 0, 0.0 218,-2.5 0, 0.0 2,-0.3 0.596 66.5 172.9 -82.5-175.6 -4.0 -4.4 23.9 29 31 A V - 0 0 1 216,-0.3 77,-1.4 -2,-0.2 2,-0.4 -0.904 38.0 -94.5-143.7 168.8 -4.3 -6.4 27.1 30 32 A D E -a 106 0A 28 216,-0.5 2,-0.8 -2,-0.3 77,-0.2 -0.754 35.3-138.4 -88.7 137.4 -5.9 -9.6 28.3 31 33 A I E -a 107 0A 0 75,-3.3 77,-1.8 -2,-0.4 2,-1.3 -0.841 8.8-155.5-101.1 104.5 -9.3 -9.1 29.7 32 34 A D >> - 0 0 63 -2,-0.8 4,-2.9 1,-0.2 3,-0.9 -0.636 3.7-164.1 -79.2 95.1 -9.7 -11.3 32.9 33 35 A T T 34 S+ 0 0 44 -2,-1.3 -1,-0.2 1,-0.3 74,-0.0 0.783 88.3 50.0 -50.0 -32.5 -13.5 -11.7 33.0 34 36 A H T 34 S+ 0 0 167 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.1 0.819 115.5 42.2 -78.8 -30.8 -13.4 -12.8 36.6 35 37 A T T <4 S+ 0 0 107 -3,-0.9 -2,-0.2 2,-0.1 -1,-0.2 0.814 88.8 100.3 -85.9 -31.4 -11.2 -9.9 37.7 36 38 A A < - 0 0 17 -4,-2.9 2,-0.4 218,-0.1 218,-0.2 -0.333 69.0-139.7 -56.6 131.4 -13.0 -7.1 35.7 37 39 A K E -c 254 0B 138 216,-1.5 218,-2.7 1,-0.0 2,-0.1 -0.797 11.9-113.8-104.0 136.1 -15.3 -5.3 38.2 38 40 A Y E -c 255 0B 83 -2,-0.4 218,-0.2 216,-0.2 220,-0.1 -0.427 30.1-154.4 -62.0 129.2 -18.9 -4.0 37.5 39 41 A D > - 0 0 31 216,-2.8 3,-1.5 -2,-0.1 -1,-0.1 -0.886 15.2-174.3-112.4 103.4 -18.8 -0.2 37.6 40 42 A P T 3 S+ 0 0 93 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.703 80.8 71.0 -69.1 -15.7 -22.2 1.3 38.5 41 43 A S T 3 S+ 0 0 94 2,-0.1 2,-0.3 40,-0.0 215,-0.1 0.424 74.9 110.0 -79.5 2.6 -20.8 4.8 37.9 42 44 A L < - 0 0 29 -3,-1.5 3,-0.1 213,-0.2 213,-0.0 -0.606 64.7-138.2 -80.4 138.2 -20.7 4.0 34.1 43 45 A K E -D 80 0B 91 37,-1.8 37,-0.6 -2,-0.3 39,-0.1 -0.608 38.8 -78.5 -91.5 156.4 -23.3 5.9 32.1 44 46 A P E - 0 0 117 0, 0.0 36,-0.6 0, 0.0 2,-0.1 -0.268 52.1-114.2 -55.5 135.8 -25.3 4.2 29.3 45 47 A L E -D 79 0B 24 34,-0.3 2,-0.4 141,-0.1 34,-0.2 -0.464 30.1-159.0 -70.4 143.4 -23.2 3.8 26.1 46 48 A S E +D 78 0B 43 32,-2.9 32,-2.5 -2,-0.1 2,-0.6 -0.914 14.2 179.0-133.1 109.7 -24.4 5.8 23.2 47 49 A V E -D 77 0B 34 -2,-0.4 2,-0.7 30,-0.2 30,-0.2 -0.927 5.3-178.7-109.9 111.9 -23.5 4.9 19.6 48 50 A S E +D 76 0B 45 28,-2.9 28,-2.2 -2,-0.6 3,-0.1 -0.854 23.9 142.4-115.7 96.2 -25.1 7.3 17.1 49 51 A Y > + 0 0 4 -2,-0.7 3,-2.3 26,-0.2 130,-0.2 0.271 33.1 112.2-113.6 6.4 -24.2 6.3 13.5 50 52 A D T 3 S+ 0 0 92 1,-0.3 -1,-0.1 128,-0.1 25,-0.1 0.812 88.4 38.3 -52.9 -30.1 -27.6 7.0 11.8 51 53 A Q T 3 S+ 0 0 126 23,-0.8 -1,-0.3 -3,-0.1 24,-0.2 0.162 84.6 144.4-107.4 19.9 -26.0 9.9 9.9 52 54 A A < - 0 0 25 -3,-2.3 2,-0.6 1,-0.1 18,-0.1 -0.270 35.9-154.3 -60.6 139.8 -22.5 8.4 9.3 53 55 A T - 0 0 47 16,-0.3 16,-2.6 122,-0.1 2,-0.1 -0.866 6.4-162.7-122.7 99.0 -21.0 9.3 5.9 54 56 A S E +E 68 0B 1 -2,-0.6 121,-0.7 122,-0.3 14,-0.3 -0.487 13.0 172.8 -77.1 148.9 -18.5 6.7 4.6 55 57 A L E - 0 0 74 12,-3.0 118,-2.7 1,-0.4 119,-0.4 0.748 47.9 -13.7-122.7 -53.4 -16.1 7.9 1.9 56 58 A R E -EF 67 172B 91 11,-0.6 11,-2.9 117,-0.3 2,-0.4 -0.987 47.1-129.4-157.0 158.2 -13.4 5.6 0.8 57 59 A I E -EF 66 171B 0 114,-2.9 114,-2.3 -2,-0.3 2,-0.4 -0.950 27.4-171.2-116.7 135.5 -11.5 2.4 1.7 58 60 A L E -EF 65 170B 31 7,-2.2 7,-3.0 -2,-0.4 2,-0.8 -0.984 25.2-143.6-133.7 139.9 -7.7 2.3 1.7 59 61 A N E -E 64 0B 0 110,-2.8 109,-2.4 -2,-0.4 5,-0.2 -0.893 21.4-177.4 -96.5 109.4 -5.0 -0.3 2.0 60 62 A N - 0 0 45 3,-2.5 4,-0.1 -2,-0.8 -1,-0.1 0.170 52.5 -95.8 -95.6 16.5 -2.3 1.4 4.1 61 63 A G S S+ 0 0 12 2,-0.3 106,-0.1 166,-0.3 3,-0.1 0.137 119.2 42.0 95.5 -27.1 0.2 -1.4 4.1 62 64 A H S S- 0 0 47 1,-0.5 2,-0.3 -58,-0.1 -1,-0.1 0.444 127.5 -13.1-128.4 -9.1 -0.7 -3.0 7.4 63 65 A A S S- 0 0 3 164,-0.1 -3,-2.5 165,-0.1 -1,-0.5 -0.952 70.7 -98.2-171.8 178.2 -4.5 -2.9 7.3 64 66 A F E -E 59 0B 0 -2,-0.3 2,-0.5 -5,-0.2 29,-0.5 -0.956 30.1-151.4-117.1 140.3 -7.4 -1.3 5.4 65 67 A N E -E 58 0B 23 -7,-3.0 -7,-2.2 -2,-0.4 2,-0.8 -0.925 9.4-155.1-113.3 132.0 -9.2 1.7 6.5 66 68 A V E -EG 57 91B 0 25,-2.5 25,-1.7 -2,-0.5 -9,-0.2 -0.916 30.4-153.0-100.8 110.9 -12.9 2.6 5.8 67 69 A E E -EG 56 90B 47 -11,-2.9 -12,-3.0 -2,-0.8 -11,-0.6 -0.571 10.0-158.6 -90.0 151.0 -12.8 6.4 6.2 68 70 A F E -E 54 0B 8 21,-2.2 2,-0.8 -14,-0.3 -14,-0.2 -0.933 29.6-105.3-128.4 151.2 -15.6 8.7 7.2 69 71 A D + 0 0 37 -16,-2.6 -16,-0.3 -2,-0.3 5,-0.3 -0.639 42.0 170.1 -72.9 110.9 -16.4 12.4 6.7 70 72 A D + 0 0 37 -2,-0.8 -1,-0.2 1,-0.1 17,-0.1 0.153 42.5 110.6-111.5 18.4 -15.7 13.7 10.2 71 73 A S S S+ 0 0 84 2,-0.1 2,-0.3 3,-0.0 -1,-0.1 0.571 89.5 28.0 -68.2 -6.0 -15.9 17.4 9.4 72 74 A Q S S- 0 0 118 -3,-0.2 2,-2.7 3,-0.0 3,-0.4 -0.958 100.0 -90.2-148.3 164.5 -19.1 17.3 11.4 73 75 A D S S+ 0 0 85 -2,-0.3 3,-0.2 1,-0.2 -3,-0.1 -0.346 72.3 135.8 -75.0 61.9 -20.8 15.4 14.3 74 76 A K S S+ 0 0 57 -2,-2.7 -23,-0.8 1,-0.3 2,-0.4 0.864 73.7 16.1 -80.1 -37.7 -22.3 12.9 11.8 75 77 A A S S+ 0 0 6 -3,-0.4 13,-2.4 13,-0.2 -1,-0.3 -0.973 82.5 170.3-138.6 118.6 -21.5 9.7 13.7 76 78 A V E -DH 48 87B 15 -28,-2.2 -28,-2.9 -2,-0.4 2,-0.4 -0.895 28.8-144.5-135.1 163.3 -20.5 9.9 17.4 77 79 A L E +DH 47 86B 0 9,-2.0 9,-1.6 -2,-0.3 2,-0.3 -0.986 32.9 152.2-124.7 130.8 -19.9 7.8 20.5 78 80 A K E +D 46 0B 73 -32,-2.5 -32,-2.9 -2,-0.4 7,-0.1 -0.890 33.9 39.6-147.5 178.0 -20.8 9.1 23.9 79 81 A G E > S+D 45 0B 15 5,-0.4 3,-1.8 3,-0.4 -34,-0.3 -0.234 73.6 81.4 72.6-165.4 -21.8 8.0 27.3 80 82 A G E 3 S-D 43 0B 1 -36,-0.6 -37,-1.8 -37,-0.6 -1,-0.1 -0.507 122.1 -24.1 66.2-131.9 -20.3 5.0 29.0 81 83 A P T 3 S+ 0 0 46 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.506 118.9 101.4 -89.5 -3.7 -17.0 6.0 30.5 82 84 A L < - 0 0 4 -3,-1.8 2,-0.5 -39,-0.1 -3,-0.4 -0.508 54.4-160.0 -85.8 146.2 -16.6 9.0 28.1 83 85 A D + 0 0 98 -2,-0.2 2,-0.1 -5,-0.1 -5,-0.0 -0.992 65.6 10.4-120.7 129.2 -17.4 12.6 28.8 84 86 A G S S- 0 0 42 -2,-0.5 2,-0.4 39,-0.1 -5,-0.4 -0.456 99.6 -53.5 100.0-175.2 -17.9 14.7 25.7 85 87 A T - 0 0 28 -2,-0.1 38,-2.6 -7,-0.1 2,-0.5 -0.894 39.7-161.0-111.7 134.2 -18.4 13.7 22.1 86 88 A Y E -HI 77 122B 2 -9,-1.6 -9,-2.0 -2,-0.4 2,-0.4 -0.967 14.9-142.4-116.0 121.6 -16.1 11.5 20.1 87 89 A R E -HI 76 121B 45 34,-2.6 34,-2.2 -2,-0.5 2,-0.3 -0.703 16.4-120.8 -89.1 130.3 -16.3 11.6 16.3 88 90 A L E + I 0 120B 3 -13,-2.4 32,-0.3 -2,-0.4 -13,-0.2 -0.490 37.0 166.0 -68.1 126.9 -15.9 8.5 14.1 89 91 A I E - 0 0 34 30,-2.8 -21,-2.2 1,-0.4 2,-0.3 0.695 60.1 -28.1-112.8 -33.2 -13.0 8.9 11.7 90 92 A Q E -GI 67 119B 34 29,-1.2 29,-2.6 -23,-0.2 -1,-0.4 -0.974 47.3-139.2-173.3 162.9 -12.5 5.4 10.5 91 93 A F E +GI 66 118B 0 -25,-1.7 -25,-2.5 -2,-0.3 2,-0.3 -0.969 24.5 163.6-133.4 152.1 -12.7 1.7 11.2 92 94 A H E - I 0 117B 22 25,-2.1 25,-3.3 -2,-0.3 2,-0.3 -0.908 22.6-124.8-152.1 177.4 -10.3 -1.1 10.5 93 95 A F E - I 0 116B 0 -29,-0.5 2,-0.4 -2,-0.3 -29,-0.2 -0.851 1.8-152.3-131.2 166.9 -9.5 -4.7 11.5 94 96 A H E + I 0 115B 3 21,-1.2 21,-1.9 -2,-0.3 2,-0.3 -0.991 32.4 164.3-135.6 130.2 -6.7 -6.9 12.8 95 97 A W E - I 0 114B 0 -2,-0.4 146,-1.1 19,-0.2 145,-0.8 -0.920 24.8-115.1-146.8 172.5 -6.8 -10.5 11.9 96 98 A G - 0 0 0 17,-1.4 6,-0.1 5,-0.6 3,-0.1 -0.302 24.8-117.0-106.6-173.6 -4.8 -13.8 11.7 97 99 A S S S+ 0 0 40 142,-0.2 2,-0.3 1,-0.1 5,-0.1 0.588 106.2 24.7 -92.0 -16.4 -3.4 -16.3 9.3 98 100 A L S > S- 0 0 115 3,-0.3 3,-1.6 15,-0.1 -2,-0.2 -0.948 89.4-105.5-143.3 161.3 -5.7 -18.9 10.9 99 101 A D T 3 S+ 0 0 68 -2,-0.3 48,-0.1 1,-0.3 15,-0.1 0.723 110.6 68.2 -63.0 -23.0 -9.0 -18.8 12.9 100 102 A G T 3 S+ 0 0 57 13,-0.1 2,-0.3 2,-0.1 11,-0.3 0.467 107.8 28.9 -78.3 -0.4 -7.3 -19.4 16.2 101 103 A Q < + 0 0 55 -3,-1.6 -5,-0.6 12,-0.1 -3,-0.3 -0.986 67.3 92.8-153.8 160.1 -5.6 -16.0 16.2 102 104 A G + 0 0 0 1,-0.6 13,-0.3 -2,-0.3 11,-0.2 0.036 56.3 106.4 145.4 -32.6 -5.9 -12.4 15.0 103 105 A S - 0 0 1 9,-2.0 -1,-0.6 11,-0.3 12,-0.1 -0.382 53.9-151.2 -74.0 156.2 -7.6 -10.4 17.8 104 106 A E S S+ 0 0 1 -10,-0.1 -1,-0.1 -3,-0.1 2,-0.1 0.876 82.0 52.0 -94.2 -54.1 -5.5 -8.0 19.7 105 107 A H S S- 0 0 0 -77,-0.1 7,-0.4 140,-0.1 2,-0.3 -0.477 78.8-154.7 -76.0 157.6 -7.4 -8.0 23.0 106 108 A T E -a 30 0A 9 -77,-1.4 -75,-3.3 5,-0.1 2,-0.6 -0.927 10.4-135.9-131.4 157.0 -8.0 -11.4 24.5 107 109 A V E > S-aB 31 110A 16 3,-1.9 3,-2.1 -2,-0.3 -75,-0.2 -0.942 89.1 -20.9-118.6 110.2 -10.7 -12.7 26.9 108 110 A D T 3 S- 0 0 66 -77,-1.8 -1,-0.2 -2,-0.6 -76,-0.1 0.918 129.0 -55.1 56.3 40.8 -9.4 -15.0 29.6 109 111 A K T 3 S+ 0 0 159 1,-0.2 2,-0.4 -3,-0.1 -1,-0.3 0.358 106.7 138.3 73.3 -3.4 -6.4 -15.5 27.3 110 112 A K B < -B 107 0A 112 -3,-2.1 -3,-1.9 -9,-0.0 2,-0.4 -0.595 42.9-148.1 -78.1 128.6 -8.7 -16.6 24.4 111 113 A K - 0 0 91 -2,-0.4 2,-0.2 -11,-0.3 -5,-0.1 -0.784 8.1-147.4 -95.4 136.7 -7.8 -15.1 21.0 112 114 A Y - 0 0 29 -7,-0.4 -9,-2.0 -2,-0.4 34,-0.2 -0.549 28.2-107.2 -97.2 166.9 -10.6 -14.5 18.4 113 115 A A S S- 0 0 4 32,-1.1 -17,-1.4 -11,-0.2 2,-0.3 0.773 93.8 -15.0 -65.4 -27.7 -10.2 -14.8 14.7 114 116 A A E -IJ 95 145B 1 31,-1.3 31,-2.6 -19,-0.2 2,-0.3 -0.959 57.9-135.6-163.8 174.6 -10.2 -11.0 14.2 115 117 A E E -IJ 94 144B 0 -21,-1.9 -21,-1.2 -2,-0.3 2,-0.4 -0.946 11.6-146.7-149.1 123.9 -11.0 -7.7 15.9 116 118 A L E -IJ 93 143B 0 27,-3.6 27,-2.3 -2,-0.3 2,-0.5 -0.766 13.1-162.8 -92.0 131.8 -12.9 -4.6 14.5 117 119 A H E -IJ 92 142B 1 -25,-3.3 -25,-2.1 -2,-0.4 2,-0.7 -0.965 6.6-166.4-119.9 116.8 -11.8 -1.2 15.7 118 120 A L E -IJ 91 141B 0 23,-2.4 23,-2.7 -2,-0.5 2,-0.5 -0.917 19.8-150.6-103.8 109.0 -14.0 1.8 15.3 119 121 A V E +IJ 90 140B 9 -29,-2.6 -30,-2.8 -2,-0.7 -29,-1.2 -0.733 18.8 176.1 -89.7 124.7 -11.8 4.9 15.9 120 122 A H E -IJ 88 139B 0 19,-1.8 19,-2.4 -2,-0.5 2,-0.4 -0.959 16.2-145.9-127.2 141.9 -13.3 8.1 17.3 121 123 A W E -IJ 87 138B 11 -34,-2.2 -34,-2.6 -2,-0.3 2,-0.5 -0.899 27.6-107.0-114.5 140.5 -11.6 11.4 18.4 122 124 A N E > -I 86 0B 2 15,-3.0 3,-2.4 -2,-0.4 -36,-0.2 -0.426 24.7-149.9 -61.3 109.4 -12.6 13.8 21.2 123 125 A T G > S+ 0 0 37 -38,-2.6 3,-1.4 -2,-0.5 -1,-0.2 0.649 88.3 78.2 -59.3 -14.8 -14.1 16.8 19.4 124 126 A K G 3 S+ 0 0 118 -39,-0.4 -1,-0.3 1,-0.2 -2,-0.1 0.744 91.4 55.1 -66.7 -19.1 -13.0 19.0 22.3 125 127 A Y G < S- 0 0 54 -3,-2.4 2,-1.4 12,-0.1 -1,-0.2 0.326 102.5-131.0 -97.3 6.6 -9.5 18.9 20.7 126 128 A G S < S+ 0 0 54 -3,-1.4 2,-0.3 -4,-0.1 -3,-0.1 -0.133 73.9 22.1 80.0 -48.5 -10.4 20.1 17.2 127 129 A D S > S- 0 0 65 -2,-1.4 4,-1.8 -5,-0.2 3,-0.4 -0.954 79.9-105.2-147.7 168.1 -8.7 17.5 15.0 128 130 A F H > S+ 0 0 69 -2,-0.3 4,-2.2 1,-0.2 -1,-0.1 0.921 115.1 58.7 -59.9 -47.1 -7.5 13.9 15.2 129 131 A G H 4 S+ 0 0 32 1,-0.2 -1,-0.2 2,-0.2 4,-0.2 0.804 110.3 41.2 -55.4 -35.3 -3.8 15.0 15.3 130 132 A K H >4 S+ 0 0 107 -3,-0.4 3,-1.1 -5,-0.2 -1,-0.2 0.828 109.6 59.5 -83.1 -32.2 -4.3 17.1 18.4 131 133 A A H >< S+ 0 0 0 -4,-1.8 3,-2.3 1,-0.2 6,-0.3 0.906 96.4 60.5 -61.9 -42.1 -6.5 14.5 20.1 132 134 A V T 3< S+ 0 0 20 -4,-2.2 -1,-0.2 1,-0.3 -2,-0.2 0.687 97.1 61.6 -62.4 -13.3 -3.8 11.8 19.9 133 135 A Q T < S+ 0 0 137 -3,-1.1 -1,-0.3 -4,-0.2 -2,-0.2 0.331 95.8 79.6 -91.6 6.6 -1.6 14.1 22.1 134 136 A Q S X S- 0 0 60 -3,-2.3 3,-2.2 69,-0.1 4,-0.3 -0.922 80.9-129.4-119.7 141.9 -4.1 13.9 24.9 135 137 A P T 3 S+ 0 0 80 0, 0.0 3,-0.2 0, 0.0 58,-0.1 0.823 115.1 32.3 -54.7 -35.2 -4.8 11.2 27.5 136 138 A D T 3 S+ 0 0 39 1,-0.1 68,-0.1 56,-0.1 -14,-0.1 -0.147 87.8 117.3-113.1 36.0 -8.5 11.2 26.7 137 139 A G S < S+ 0 0 0 -3,-2.2 -15,-3.0 -6,-0.3 2,-0.3 0.846 71.2 33.5 -72.8 -36.2 -8.0 12.0 23.0 138 140 A L E -Jk 121 204B 0 65,-3.1 67,-2.3 -4,-0.3 2,-0.4 -0.859 53.2-161.9-124.8 158.2 -9.5 8.9 21.5 139 141 A A E -Jk 120 205B 0 -19,-2.4 -19,-1.8 -2,-0.3 2,-0.5 -0.978 15.9-166.4-133.8 115.8 -12.2 6.3 22.1 140 142 A V E -Jk 119 206B 6 65,-1.6 67,-2.3 -2,-0.4 2,-0.7 -0.939 9.3-150.6-111.5 124.2 -11.8 3.1 20.2 141 143 A L E -Jk 118 207B 0 -23,-2.7 -23,-2.4 -2,-0.5 2,-0.4 -0.820 16.6-159.6 -91.8 116.0 -14.8 0.6 20.1 142 144 A G E -Jk 117 208B 0 65,-3.3 67,-2.5 -2,-0.7 2,-0.4 -0.826 12.1-177.7-102.3 138.3 -13.5 -2.9 19.8 143 145 A I E -J 116 0B 0 -27,-2.3 -27,-3.6 -2,-0.4 2,-0.1 -0.985 20.3-136.4-134.8 119.4 -15.7 -5.8 18.4 144 146 A F E -J 115 0B 0 65,-0.4 69,-2.4 -2,-0.4 2,-0.4 -0.412 13.2-143.9 -73.7 151.8 -14.3 -9.4 18.3 145 147 A L E -Jl 114 213B 3 -31,-2.6 -31,-1.3 67,-0.2 -32,-1.1 -0.970 16.1-176.9-119.7 130.4 -14.9 -11.6 15.2 146 148 A K E - l 0 214B 82 67,-2.3 69,-2.6 -2,-0.4 2,-0.5 -0.938 31.2-111.2-123.8 148.8 -15.5 -15.3 15.4 147 149 A V E S+ l 0 215B 45 -2,-0.4 69,-0.2 67,-0.2 2,-0.2 -0.694 72.6 92.8 -85.4 122.1 -16.0 -17.6 12.5 148 150 A G S S+ 0 0 39 67,-3.3 69,-0.4 -2,-0.5 2,-0.1 -0.489 79.6 8.3-165.5-118.8 -19.5 -19.0 12.0 149 151 A S S S- 0 0 88 -2,-0.2 -1,-0.4 67,-0.1 2,-0.0 -0.471 86.8 -93.4 -79.3 156.1 -22.3 -17.6 10.0 150 152 A A - 0 0 53 65,-0.3 65,-0.2 -2,-0.1 -1,-0.1 -0.323 28.4-128.0 -68.0 148.5 -21.7 -14.7 7.6 151 153 A K >> - 0 0 41 1,-0.2 3,-2.0 65,-0.1 4,-0.9 -0.867 13.9-158.1 -99.3 106.9 -22.2 -11.1 8.7 152 154 A P H >> S+ 0 0 112 0, 0.0 3,-1.3 0, 0.0 4,-0.5 0.923 90.7 58.0 -51.0 -47.7 -24.5 -9.5 6.0 153 155 A G H 34 S+ 0 0 23 27,-0.5 27,-0.2 1,-0.2 4,-0.2 0.596 105.3 51.5 -60.6 -11.7 -23.3 -6.0 7.0 154 156 A L H X> S+ 0 0 1 -3,-2.0 4,-2.2 26,-0.2 3,-0.9 0.625 85.0 84.3 -99.8 -17.3 -19.7 -6.9 6.3 155 157 A Q H S+ 0 0 0 -3,-0.9 3,-0.8 2,-0.2 4,-0.8 0.949 111.7 49.0 -70.0 -49.8 -16.5 -4.6 2.7 158 160 A V H >< S+ 0 0 3 -4,-2.2 3,-0.8 1,-0.2 4,-0.4 0.890 107.3 55.8 -56.4 -43.5 -15.4 -8.1 1.7 159 161 A D H 3< S+ 0 0 94 -4,-3.2 3,-0.4 1,-0.2 -1,-0.2 0.739 105.2 50.6 -65.0 -25.8 -16.4 -7.6 -1.9 160 162 A V H X< S+ 0 0 26 -4,-0.8 3,-1.7 -3,-0.8 4,-0.3 0.614 84.3 86.8 -89.8 -11.6 -14.3 -4.4 -2.5 161 163 A L G X< S+ 0 0 7 -3,-0.8 3,-1.4 -4,-0.8 -1,-0.2 0.786 78.1 68.0 -58.4 -27.9 -11.0 -5.9 -1.1 162 164 A D G > S+ 0 0 135 -3,-0.4 3,-0.6 -4,-0.4 -1,-0.3 0.828 99.2 51.4 -60.0 -31.9 -10.3 -7.3 -4.6 163 165 A S G < S+ 0 0 49 -3,-1.7 -1,-0.3 1,-0.2 -2,-0.2 0.476 114.1 40.6 -86.8 -4.0 -9.8 -3.7 -5.8 164 166 A I G < + 0 0 0 -3,-1.4 -1,-0.2 -4,-0.3 63,-0.2 -0.178 69.4 137.7-135.6 42.5 -7.4 -2.6 -3.0 165 167 A K < + 0 0 98 -3,-0.6 62,-3.6 61,-0.1 2,-0.2 0.856 61.9 50.2 -57.2 -41.3 -5.1 -5.7 -2.7 166 168 A T S > S- 0 0 9 60,-0.2 3,-2.0 1,-0.1 64,-0.3 -0.627 98.0 -77.2-108.2 162.0 -1.8 -3.8 -2.5 167 169 A K B 3 S+o 230 0C 91 62,-2.7 64,-0.5 1,-0.3 -107,-0.2 -0.188 113.4 20.9 -54.6 135.2 -0.4 -1.0 -0.4 168 170 A G T 3 S+ 0 0 55 -109,-2.4 -1,-0.3 1,-0.3 2,-0.2 0.195 91.1 127.0 91.9 -16.2 -1.5 2.5 -1.5 169 171 A K < + 0 0 85 -3,-2.0 -110,-2.8 -110,-0.1 -1,-0.3 -0.508 32.0 174.7 -79.6 143.6 -4.6 1.3 -3.3 170 172 A S E -F 58 0B 54 -112,-0.2 2,-0.3 -2,-0.2 -112,-0.2 -0.952 12.6-162.2-141.8 160.8 -8.0 2.9 -2.4 171 173 A A E -F 57 0B 19 -114,-2.3 -114,-2.9 -2,-0.3 -116,-0.0 -0.992 35.4 -93.1-146.0 147.4 -11.5 2.7 -3.7 172 174 A D E +F 56 0B 119 -2,-0.3 -116,-0.3 -116,-0.2 -117,-0.1 -0.353 41.2 175.3 -57.8 134.7 -14.6 4.8 -3.4 173 175 A F + 0 0 20 -118,-2.7 3,-0.5 -106,-0.1 -117,-0.3 -0.174 15.5 154.1-140.7 47.1 -16.7 3.5 -0.5 174 176 A T + 0 0 60 -119,-0.4 -119,-0.2 1,-0.2 -121,-0.1 -0.272 55.8 27.4 -74.5 160.8 -19.6 5.9 -0.0 175 177 A N S S+ 0 0 151 -121,-0.7 2,-0.5 1,-0.2 -1,-0.2 0.781 75.3 146.2 59.8 35.8 -23.0 4.9 1.5 176 178 A F - 0 0 17 -3,-0.5 -122,-0.3 -20,-0.0 -1,-0.2 -0.894 40.6-143.5-103.7 128.8 -21.8 2.2 3.8 177 179 A D > - 0 0 68 -2,-0.5 3,-1.7 1,-0.1 -127,-0.1 -0.789 7.6-164.1 -94.3 108.6 -23.7 1.8 7.1 178 180 A P G > S+ 0 0 1 0, 0.0 3,-1.8 0, 0.0 4,-0.2 0.609 79.6 81.4 -65.8 -11.5 -21.4 0.8 10.0 179 181 A R G > S+ 0 0 115 1,-0.3 3,-1.1 -130,-0.2 -26,-0.1 0.708 78.7 71.5 -66.9 -16.4 -24.4 -0.2 12.2 180 182 A G G < S+ 0 0 30 -3,-1.7 -27,-0.5 1,-0.2 -1,-0.3 0.491 91.1 57.7 -77.8 -2.0 -24.4 -3.4 10.2 181 183 A L G < S+ 0 0 0 -3,-1.8 -1,-0.2 -28,-0.1 -2,-0.2 0.366 85.0 101.8-106.8 1.6 -21.2 -4.5 12.0 182 184 A L < - 0 0 34 -3,-1.1 -29,-0.1 -4,-0.2 4,-0.1 -0.632 66.5-129.6 -92.1 145.4 -22.5 -4.3 15.6 183 185 A P - 0 0 12 0, 0.0 30,-0.1 0, 0.0 -1,-0.1 -0.254 33.6-101.9 -78.4 176.1 -23.6 -7.2 17.8 184 186 A E S S+ 0 0 189 -2,-0.0 2,-0.2 2,-0.0 29,-0.0 0.910 101.0 57.7 -67.0 -46.8 -27.0 -7.1 19.5 185 187 A S - 0 0 32 1,-0.1 26,-0.2 2,-0.0 24,-0.0 -0.583 59.3-159.4 -91.4 151.9 -25.7 -6.2 23.0 186 188 A L + 0 0 65 -2,-0.2 -1,-0.1 23,-0.1 -141,-0.1 0.243 44.5 137.6-109.1 9.1 -23.6 -3.3 24.0 187 189 A D + 0 0 58 22,-0.1 23,-1.8 1,-0.0 24,-0.5 -0.277 34.5 167.3 -52.0 141.4 -22.3 -4.8 27.2 188 190 A Y E -M 209 0B 5 21,-0.3 68,-2.6 22,-0.1 69,-0.4 -0.964 40.2-126.2-155.6 172.3 -18.6 -4.0 27.4 189 191 A W E -MN 208 255B 15 19,-2.3 19,-2.9 -2,-0.3 2,-0.3 -0.937 29.9-166.7-120.4 143.4 -15.3 -3.7 29.3 190 192 A T E +MN 207 254B 9 64,-2.5 64,-2.5 -2,-0.4 17,-0.2 -0.989 16.5 151.4-137.8 147.6 -13.4 -0.5 29.5 191 193 A Y E -M 206 0B 6 15,-1.4 15,-2.3 -2,-0.3 2,-0.5 -0.969 46.5 -94.4-164.4 156.6 -9.9 0.6 30.5 192 194 A P E +M 205 0B 57 0, 0.0 13,-0.2 0, 0.0 2,-0.2 -0.677 63.1 128.0 -81.4 125.2 -7.4 3.4 29.7 193 195 A G E -M 204 0B 0 11,-3.4 11,-1.7 -2,-0.5 2,-0.2 -0.509 41.8 -92.6-147.5-143.5 -4.8 2.4 27.1 194 196 A S - 0 0 0 8,-0.2 8,-0.2 9,-0.2 7,-0.1 -0.765 42.9 -69.8-141.5-178.6 -3.1 3.2 23.8 195 197 A L - 0 0 29 6,-2.0 -168,-0.5 -2,-0.2 -1,-0.1 -0.492 39.7-140.9 -69.8 150.3 -2.9 2.9 20.1 196 198 A T S S+ 0 0 7 -2,-0.1 -1,-0.1 -170,-0.1 -170,-0.0 0.438 83.2 55.6 -96.0 0.0 -2.0 -0.7 19.2 197 199 A T S > S- 0 0 30 4,-0.1 3,-2.8 1,-0.0 4,-0.2 -0.891 102.8 -50.4-124.5 156.5 0.3 0.4 16.4 198 200 A P T 3 S+ 0 0 9 0, 0.0 -2,-0.1 0, 0.0 -1,-0.0 -0.333 123.0 45.8 -55.9 151.4 3.2 2.8 16.5 199 201 A P T 3 S- 0 0 58 0, 0.0 -179,-0.1 0, 0.0 -178,-0.0 -0.958 84.0-163.2 -72.4 9.9 3.4 5.6 17.6 200 202 A L < - 0 0 0 -3,-2.8 -173,-0.1 1,-0.2 -182,-0.0 0.749 16.4-174.0 50.5 27.9 1.6 3.7 20.4 201 203 A L - 0 0 57 -4,-0.2 -6,-2.0 1,-0.1 2,-1.7 -0.227 29.6-127.2 -52.7 137.6 0.5 7.0 22.0 202 204 A E S S+ 0 0 46 -8,-0.2 -8,-0.2 1,-0.2 -1,-0.1 -0.476 75.5 114.1 -88.9 68.1 -1.3 6.5 25.3 203 205 A C + 0 0 1 -2,-1.7 -65,-3.1 -67,-0.1 2,-0.4 0.140 46.5 108.7-122.1 16.9 -4.3 8.5 24.2 204 206 A V E -kM 138 193B 0 -11,-1.7 -11,-3.4 -3,-0.2 2,-0.7 -0.840 48.1-162.7-115.3 138.3 -7.1 5.9 24.2 205 207 A T E -kM 139 192B 26 -67,-2.3 -65,-1.6 -2,-0.4 2,-0.4 -0.943 31.7-148.7-105.0 110.3 -10.1 5.0 26.2 206 208 A W E -kM 140 191B 5 -15,-2.3 -15,-1.4 -2,-0.7 2,-0.5 -0.677 18.0-174.2 -87.4 134.8 -10.9 1.4 25.1 207 209 A I E -kM 141 190B 0 -67,-2.3 -65,-3.3 -2,-0.4 2,-0.6 -0.969 8.4-172.8-127.0 107.8 -14.4 0.1 25.0 208 210 A V E -kM 142 189B 0 -19,-2.9 -19,-2.3 -2,-0.5 -65,-0.2 -0.924 18.8-135.1-111.4 116.7 -14.4 -3.6 24.1 209 211 A L E - M 0 188B 0 -67,-2.5 -65,-0.4 -2,-0.6 -21,-0.3 -0.433 4.5-146.3 -68.6 136.5 -17.8 -5.2 23.5 210 212 A K S S+ 0 0 65 -23,-1.8 -1,-0.1 -2,-0.1 -22,-0.1 0.848 80.9 74.7 -72.8 -34.9 -18.3 -8.6 25.3 211 213 A E S S- 0 0 58 -24,-0.5 -67,-0.1 -26,-0.2 -2,-0.1 -0.692 74.4-149.0 -86.4 118.1 -20.4 -10.0 22.5 212 214 A P - 0 0 30 0, 0.0 2,-0.3 0, 0.0 -67,-0.2 -0.355 11.5-126.5 -79.4 161.8 -18.6 -11.0 19.3 213 215 A I E -l 145 0B 4 -69,-2.4 -67,-2.3 -30,-0.1 2,-0.4 -0.802 23.6-122.5-103.7 153.5 -20.1 -10.8 15.8 214 216 A S E +l 146 0B 33 -2,-0.3 2,-0.3 -69,-0.2 -67,-0.2 -0.810 29.7 177.6 -99.0 135.9 -20.0 -13.9 13.6 215 217 A V E -l 147 0B 1 -69,-2.6 -67,-3.3 -2,-0.4 -65,-0.3 -0.916 29.7-108.3-129.6 157.0 -18.4 -13.8 10.2 216 218 A S > - 0 0 11 -2,-0.3 4,-2.3 -69,-0.2 5,-0.2 -0.495 22.6-117.0 -87.3 159.0 -18.1 -16.7 7.7 217 219 A S H > S+ 0 0 46 -69,-0.4 4,-3.2 1,-0.2 5,-0.2 0.928 118.8 55.8 -55.0 -45.3 -14.9 -18.5 6.8 218 220 A E H > S+ 0 0 132 1,-0.2 4,-1.2 2,-0.2 -1,-0.2 0.870 106.9 50.7 -53.4 -43.8 -15.4 -17.2 3.2 219 221 A Q H >> S+ 0 0 1 -3,-0.2 4,-1.1 2,-0.2 3,-0.7 0.968 113.7 41.6 -62.0 -56.0 -15.5 -13.7 4.6 220 222 A V H >X S+ 0 0 4 -4,-2.3 4,-1.9 1,-0.2 3,-0.8 0.913 107.7 61.8 -59.9 -42.8 -12.3 -13.9 6.7 221 223 A L H 3< S+ 0 0 88 -4,-3.2 4,-0.3 1,-0.3 -1,-0.2 0.850 100.4 55.1 -54.0 -33.0 -10.4 -15.8 3.9 222 224 A K H X< S+ 0 0 88 -4,-1.2 3,-1.3 -3,-0.7 -1,-0.3 0.867 102.2 55.9 -68.7 -34.4 -10.9 -12.8 1.7 223 225 A F H X< S+ 0 0 2 -4,-1.1 3,-1.7 -3,-0.8 -2,-0.2 0.931 103.4 56.7 -59.7 -43.5 -9.2 -10.6 4.4 224 226 A R T 3< S+ 0 0 26 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.526 93.7 68.0 -68.8 -3.9 -6.2 -12.9 4.1 225 227 A K T < S+ 0 0 135 -3,-1.3 -1,-0.3 -4,-0.3 -2,-0.2 0.496 78.4 102.5 -92.4 -5.9 -5.9 -12.3 0.4 226 228 A L < - 0 0 2 -3,-1.7 12,-3.6 12,-0.3 2,-0.3 -0.363 68.8-127.1 -73.6 159.2 -4.8 -8.7 0.8 227 229 A N B -P 237 0D 3 -62,-3.6 -166,-0.3 10,-0.3 10,-0.2 -0.860 15.9-157.6-113.3 147.9 -1.1 -7.7 0.5 228 230 A F S S+ 0 0 41 8,-2.6 -1,-0.1 -2,-0.3 9,-0.1 0.788 81.6 76.9 -81.9 -36.2 1.2 -5.8 2.9 229 231 A N S S- 0 0 3 7,-0.5 -62,-2.7 5,-0.1 -2,-0.1 -0.200 85.9-111.3 -73.5 164.5 3.3 -5.1 -0.2 230 232 A G B > -o 167 0C 7 -64,-0.3 3,-1.6 1,-0.2 -1,-0.1 -0.451 55.0 -61.7 -90.3 170.0 2.7 -2.5 -2.9 231 233 A E T 3 S+ 0 0 155 -64,-0.5 -1,-0.2 1,-0.2 4,-0.0 -0.124 119.6 15.5 -53.8 140.0 1.8 -3.4 -6.5 232 234 A G T 3 S+ 0 0 84 1,-0.3 -1,-0.2 -3,-0.1 3,-0.1 0.492 99.6 114.5 76.7 1.9 4.4 -5.4 -8.5 233 235 A E S < S- 0 0 98 -3,-1.6 -1,-0.3 1,-0.1 3,-0.1 -0.673 82.1 -75.1-103.0 159.2 6.4 -6.5 -5.5 234 236 A P - 0 0 114 0, 0.0 2,-0.3 0, 0.0 -1,-0.1 -0.220 63.6 -98.8 -50.9 138.1 6.8 -10.0 -4.1 235 237 A E + 0 0 117 -3,-0.1 2,-0.5 -7,-0.1 -8,-0.0 -0.453 40.5 179.0 -69.0 127.7 3.6 -11.0 -2.4 236 238 A E - 0 0 110 -2,-0.3 -8,-2.6 -3,-0.1 -7,-0.5 -0.929 30.9-131.2-124.9 97.0 3.5 -10.8 1.3 237 239 A L B -P 227 0D 87 -2,-0.5 2,-1.4 -10,-0.2 -10,-0.3 -0.249 18.1-120.8 -53.2 133.0 -0.0 -11.9 2.4 238 240 A M + 0 0 0 -12,-3.6 -12,-0.3 -15,-0.2 2,-0.3 -0.631 64.0 128.9 -78.6 91.9 -1.6 -9.4 4.8 239 241 A V + 0 0 29 -2,-1.4 -143,-0.2 1,-0.1 -142,-0.2 -0.971 51.1 25.5-144.6 158.9 -2.2 -11.6 7.9 240 242 A D + 0 0 43 -145,-0.8 2,-0.8 -2,-0.3 -144,-0.2 0.889 63.5 157.2 54.9 44.5 -1.4 -11.6 11.6 241 243 A N + 0 0 0 -146,-1.1 2,-0.4 -3,-0.1 -1,-0.2 -0.304 34.7 115.6 -93.4 51.2 -1.3 -7.8 11.8 242 244 A W - 0 0 35 -2,-0.8 -139,-0.1 -148,-0.1 -138,-0.1 -0.932 62.6-133.5-123.7 144.2 -2.1 -7.8 15.5 243 245 A R - 0 0 4 -2,-0.4 3,-0.1 -141,-0.1 -2,-0.1 -0.792 32.9-120.6 -92.6 133.9 -0.1 -6.7 18.5 244 246 A P - 0 0 40 0, 0.0 -140,-0.1 0, 0.0 -1,-0.1 -0.187 43.2 -68.3 -69.7 169.3 -0.1 -9.3 21.4 245 247 A A - 0 0 47 -216,-0.1 -216,-0.3 -141,-0.1 -218,-0.1 -0.260 51.8-152.2 -59.1 141.3 -1.4 -8.6 24.9 246 248 A Q - 0 0 39 -218,-2.5 -216,-0.5 -220,-0.2 -1,-0.1 -0.665 33.4 -71.6-111.5 165.7 0.7 -6.1 27.0 247 249 A P - 0 0 74 0, 0.0 -221,-0.4 0, 0.0 -1,-0.1 -0.306 31.9-146.8 -60.4 136.1 1.2 -5.8 30.8 248 250 A L + 0 0 60 1,-0.2 3,-0.1 -223,-0.1 -219,-0.0 0.854 37.3 166.5 -70.9 -35.3 -1.9 -4.5 32.6 249 251 A K - 0 0 92 1,-0.2 2,-1.6 -224,-0.1 -1,-0.2 -0.232 64.3 -3.3 56.1-138.1 0.3 -2.8 35.1 250 252 A N S S+ 0 0 156 -226,-0.3 2,-0.3 2,-0.0 -1,-0.2 -0.312 107.8 109.2 -84.4 57.7 -1.5 -0.2 37.3 251 253 A R - 0 0 26 -2,-1.6 2,-0.4 -3,-0.1 -3,-0.0 -0.930 51.9-151.0-133.8 156.1 -4.9 -0.5 35.6 252 254 A Q - 0 0 143 -2,-0.3 2,-0.6 -62,-0.0 -216,-0.1 -0.988 15.8-140.3-126.7 124.8 -8.4 -1.9 36.4 253 255 A I - 0 0 11 -2,-0.4 -216,-1.5 -62,-0.1 2,-0.3 -0.757 22.7-155.6 -86.8 121.8 -10.7 -3.2 33.7 254 256 A K E -cN 37 190B 43 -64,-2.5 -64,-2.5 -2,-0.6 2,-0.4 -0.717 2.8-141.7 -98.7 148.6 -14.3 -2.1 34.5 255 257 A A E -cN 38 189B 4 -218,-2.7 -216,-2.8 -2,-0.3 -66,-0.2 -0.878 9.2-151.4-111.0 142.8 -17.4 -3.8 33.3 256 258 A S S S+ 0 0 29 -68,-2.6 2,-0.4 -2,-0.4 -67,-0.1 0.590 80.5 69.1 -81.5 -12.9 -20.6 -2.1 32.1 257 259 A F 0 0 50 -69,-0.4 -2,-0.1 1,-0.1 -218,-0.0 -0.891 360.0 360.0-118.5 141.7 -22.6 -5.2 33.2 258 260 A K 0 0 218 -2,-0.4 -220,-0.1 -220,-0.1 -1,-0.1 0.514 360.0 360.0 -69.4 360.0 -23.5 -6.7 36.6