==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=30-DEC-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER LYASE 28-OCT-05 2EU2 . COMPND 2 MOLECULE: CARBONIC ANHYDRASE 2; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR S.Z.FISHER,L.GOVINDASAMY,N.BOYLE,M.AGBANDJE-MCKENNA, . 257 1 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 12061.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 156 60.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 55 21.4 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 2 0.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 20 7.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 12.8 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 6.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 2 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 3 2 0 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 4 A H 0 0 186 0, 0.0 2,-0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0-157.2 10.4 -0.1 8.8 2 5 A W + 0 0 47 1,-0.1 2,-0.2 2,-0.1 7,-0.2 -0.270 360.0 127.6 -83.6 156.2 7.9 -1.7 11.2 3 6 A G - 0 0 7 5,-2.4 10,-0.1 2,-0.2 -1,-0.1 -0.791 64.3 -79.7-165.4-146.3 5.7 -4.7 10.5 4 7 A Y S S+ 0 0 39 -2,-0.2 5,-0.2 5,-0.2 237,-0.1 0.295 83.6 105.5-123.8 6.7 4.6 -8.2 11.7 5 8 A G S >> S- 0 0 40 4,-0.1 4,-1.7 1,-0.1 3,-0.5 -0.195 85.0 -95.0 -82.8 177.9 7.5 -10.4 10.6 6 9 A K T 34 S+ 0 0 162 1,-0.2 -1,-0.1 2,-0.2 5,-0.1 0.820 122.8 39.7 -63.3 -31.6 10.4 -12.0 12.5 7 10 A H T 34 S+ 0 0 144 1,-0.1 -1,-0.2 5,-0.0 -3,-0.0 0.598 131.4 22.5-100.0 -7.7 12.8 -9.2 11.8 8 11 A N T <4 S+ 0 0 60 -3,-0.5 -5,-2.4 -6,-0.1 -2,-0.2 0.215 96.7 115.7-138.2 15.6 10.4 -6.1 12.1 9 12 A G S >X S- 0 0 3 -4,-1.7 3,-2.8 -5,-0.2 4,-0.8 0.091 83.9 -64.2 -83.8-173.7 7.6 -7.4 14.3 10 13 A P T 34 S+ 0 0 27 0, 0.0 4,-0.4 0, 0.0 3,-0.3 0.697 127.3 59.9 -45.0 -34.0 6.2 -6.6 17.8 11 14 A E T 34 S+ 0 0 146 1,-0.2 -5,-0.0 2,-0.1 -2,-0.0 0.577 110.1 43.9 -77.6 -6.3 9.4 -7.7 19.7 12 15 A H T X4 S+ 0 0 61 -3,-2.8 3,-1.8 1,-0.1 4,-0.5 0.623 87.5 88.7-103.1 -18.2 11.5 -5.1 17.7 13 16 A W G >X S+ 0 0 7 -4,-0.8 4,-2.2 -3,-0.3 3,-0.8 0.788 74.1 70.0 -59.6 -31.8 9.1 -2.0 17.9 14 17 A H G 34 S+ 0 0 68 -4,-0.4 -1,-0.3 1,-0.2 7,-0.1 0.753 86.4 66.9 -61.8 -23.1 10.5 -0.7 21.2 15 18 A K G <4 S+ 0 0 138 -3,-1.8 -1,-0.2 1,-0.2 -2,-0.2 0.919 117.4 23.7 -68.0 -37.3 13.9 0.4 19.5 16 19 A D T <4 S+ 0 0 113 -3,-0.8 -2,-0.2 -4,-0.5 -1,-0.2 0.725 136.1 36.6 -91.5 -25.0 12.1 3.1 17.5 17 20 A F >< - 0 0 51 -4,-2.2 3,-2.4 1,-0.1 -1,-0.2 -0.751 65.0-179.0-130.8 77.9 9.1 3.5 19.9 18 21 A P G > S+ 0 0 103 0, 0.0 3,-1.9 0, 0.0 -4,-0.1 0.711 75.6 76.7 -58.3 -23.5 10.3 3.1 23.5 19 22 A I G > S+ 0 0 65 1,-0.3 3,-2.5 179,-0.2 -5,-0.1 0.648 70.9 87.9 -60.3 -12.8 6.7 3.7 24.8 20 23 A A G < S+ 0 0 7 -3,-2.4 -1,-0.3 1,-0.3 -6,-0.1 0.746 90.8 45.8 -53.7 -28.3 6.2 0.0 23.6 21 24 A K G < S+ 0 0 143 -3,-1.9 -1,-0.3 -7,-0.1 -2,-0.2 -0.001 96.9 130.0-102.2 26.5 7.4 -0.9 27.1 22 25 A G S < S- 0 0 13 -3,-2.5 3,-0.4 1,-0.1 -3,-0.1 0.112 71.8-102.0 -76.7-174.3 5.1 1.7 28.8 23 26 A E S S+ 0 0 123 1,-0.2 226,-0.3 225,-0.1 -1,-0.1 0.545 112.0 36.2 -90.1 -9.4 2.7 1.6 31.6 24 27 A R S S+ 0 0 50 224,-0.1 -1,-0.2 2,-0.0 2,-0.2 -0.237 78.8 154.2-141.8 54.5 -0.7 1.5 29.6 25 28 A Q - 0 0 4 -3,-0.4 220,-0.2 221,-0.3 170,-0.1 -0.446 33.0-100.4 -86.7 153.3 -0.0 -0.6 26.5 26 29 A S S S+ 0 0 0 168,-0.5 2,-0.2 -2,-0.2 -2,-0.0 -0.891 76.9 38.7-126.2 157.2 -2.6 -2.5 24.5 27 30 A P + 0 0 0 0, 0.0 218,-2.7 0, 0.0 2,-0.3 0.606 65.2 177.7 -79.5-177.7 -4.0 -5.1 23.8 28 31 A V - 0 0 1 216,-0.3 77,-1.2 -2,-0.2 2,-0.4 -0.921 35.9 -99.0-137.1 162.0 -4.3 -7.1 27.1 29 32 A D E -a 105 0A 30 216,-0.4 2,-0.8 -2,-0.3 77,-0.2 -0.719 34.2-139.7 -77.6 133.4 -5.8 -10.4 28.2 30 33 A I E -a 106 0A 0 75,-2.9 77,-2.5 -2,-0.4 2,-0.9 -0.869 10.0-158.1 -97.2 104.5 -9.3 -9.9 29.7 31 34 A D >> - 0 0 66 -2,-0.8 4,-1.9 75,-0.2 3,-0.6 -0.759 4.4-161.4 -83.5 107.7 -9.6 -12.2 32.8 32 35 A T T 34 S+ 0 0 46 -2,-0.9 -1,-0.2 1,-0.3 222,-0.0 0.751 86.6 53.7 -68.5 -26.1 -13.4 -12.5 33.1 33 36 A H T 34 S+ 0 0 167 1,-0.2 -1,-0.3 -3,-0.1 -2,-0.0 0.840 113.5 43.1 -77.0 -30.1 -13.3 -13.7 36.7 34 37 A T T <4 S+ 0 0 114 -3,-0.6 -2,-0.2 2,-0.1 -1,-0.2 0.662 90.6 95.7 -86.8 -28.4 -11.1 -10.6 37.8 35 38 A A < - 0 0 17 -4,-1.9 2,-0.5 218,-0.1 218,-0.2 -0.336 68.9-142.8 -62.0 142.7 -13.0 -7.9 35.8 36 39 A K E -c 253 0B 133 216,-1.9 218,-2.5 221,-0.0 2,-0.1 -0.899 12.2-112.3-123.5 143.1 -15.5 -6.2 38.1 37 40 A Y E -c 254 0B 100 -2,-0.5 218,-0.2 216,-0.2 220,-0.1 -0.429 31.2-154.0 -60.4 131.1 -19.0 -4.8 37.4 38 41 A D > - 0 0 34 216,-2.4 3,-1.0 -2,-0.1 -1,-0.1 -0.924 15.6-170.7-114.7 106.7 -19.0 -0.9 37.7 39 42 A P T 3 S+ 0 0 102 0, 0.0 -1,-0.1 0, 0.0 216,-0.0 0.650 83.0 70.8 -67.8 -14.6 -22.3 0.8 38.6 40 43 A S T 3 S+ 0 0 87 2,-0.1 2,-0.1 40,-0.0 -2,-0.0 0.748 74.7 105.3 -76.5 -16.9 -20.8 4.3 37.8 41 44 A L < - 0 0 33 -3,-1.0 38,-0.0 213,-0.2 213,-0.0 -0.358 69.3-135.1 -62.4 136.3 -20.8 3.5 34.1 42 45 A K - 0 0 97 37,-1.7 37,-0.4 -2,-0.1 39,-0.1 -0.563 37.0 -86.4 -92.0 159.3 -23.6 5.3 32.1 43 46 A P - 0 0 134 0, 0.0 35,-0.1 0, 0.0 -2,-0.1 0.340 55.8-114.3 -50.4 -31.2 -25.6 3.3 29.5 44 47 A L - 0 0 17 33,-0.1 2,-0.5 1,-0.1 34,-0.2 0.783 24.2-151.9 94.0 134.3 -23.5 3.4 26.1 45 48 A S E -D 77 0B 38 32,-2.8 32,-2.2 2,-0.0 2,-0.6 -0.972 11.9-175.5-129.0 108.3 -24.8 5.2 23.0 46 49 A V E -D 76 0B 33 -2,-0.5 2,-0.6 30,-0.2 30,-0.2 -0.945 8.5-178.4-102.8 112.6 -23.8 4.2 19.5 47 50 A S E +D 75 0B 41 28,-2.8 28,-1.8 -2,-0.6 3,-0.2 -0.794 22.9 144.1-121.4 89.2 -25.4 6.8 17.1 48 51 A Y > + 0 0 5 -2,-0.6 3,-1.7 26,-0.2 130,-0.2 0.291 32.3 110.1-112.3 8.4 -24.5 5.8 13.5 49 52 A D T 3 S+ 0 0 96 1,-0.3 -1,-0.2 127,-0.1 25,-0.1 0.772 86.1 40.2 -57.4 -32.1 -27.8 6.7 11.6 50 53 A Q T 3 S+ 0 0 131 23,-0.9 -1,-0.3 -3,-0.2 24,-0.2 0.172 83.5 146.3-104.2 21.4 -26.1 9.6 9.7 51 54 A A < - 0 0 25 -3,-1.7 2,-0.5 22,-0.1 123,-0.1 -0.247 32.0-160.7 -60.5 139.5 -22.8 7.9 9.0 52 55 A T - 0 0 46 16,-0.3 16,-2.6 122,-0.1 2,-0.1 -0.859 4.1-164.3-122.3 97.2 -21.1 8.8 5.7 53 56 A S E +E 67 0B 1 -2,-0.5 121,-0.5 122,-0.4 14,-0.3 -0.373 11.8 173.6 -73.1 154.7 -18.5 6.3 4.5 54 57 A L E - 0 0 78 12,-2.9 118,-1.9 1,-0.4 2,-0.3 0.714 49.2 -6.2-127.0 -43.2 -16.1 7.6 1.8 55 58 A R E -EF 66 171B 86 11,-1.0 11,-2.7 116,-0.3 -1,-0.4 -0.981 45.0-134.5-160.8 158.0 -13.3 5.2 0.9 56 59 A I E -EF 65 170B 0 114,-2.3 114,-2.2 -2,-0.3 2,-0.4 -0.987 27.4-172.6-124.8 134.3 -11.4 1.9 1.6 57 60 A L E -EF 64 169B 34 7,-2.2 7,-2.4 -2,-0.4 2,-0.7 -0.994 24.7-143.9-135.0 132.3 -7.6 1.9 1.7 58 61 A N E -E 63 0B 0 110,-2.6 109,-3.0 -2,-0.4 5,-0.2 -0.878 21.4-178.7 -87.5 110.9 -4.8 -0.9 2.0 59 62 A N - 0 0 54 3,-1.9 4,-0.1 -2,-0.7 -1,-0.1 0.249 52.2 -99.9 -95.8 6.7 -2.1 0.8 4.1 60 63 A G S S+ 0 0 8 2,-0.5 3,-0.1 166,-0.2 106,-0.1 0.337 118.5 53.5 92.8 -9.8 0.4 -2.1 4.1 61 64 A H S S- 0 0 44 1,-0.6 2,-0.2 -58,-0.1 -1,-0.1 0.671 124.7 -31.3-125.0 -40.8 -0.7 -3.3 7.6 62 65 A A S S- 0 0 7 -5,-0.1 -3,-1.9 31,-0.1 -1,-0.6 -0.774 71.0 -89.4-156.7-166.8 -4.5 -3.7 7.4 63 66 A F E -E 58 0B 0 29,-0.3 29,-0.5 -5,-0.2 2,-0.4 -0.985 33.4-151.3-119.6 141.4 -7.3 -2.0 5.4 64 67 A N E -E 57 0B 26 -7,-2.4 -7,-2.2 -2,-0.4 2,-0.6 -0.932 7.9-153.2-109.1 133.3 -9.2 1.1 6.7 65 68 A V E -EG 56 90B 0 25,-2.7 25,-1.9 -2,-0.4 2,-0.3 -0.937 29.0-151.6 -96.9 118.1 -12.8 2.1 5.8 66 69 A E E -EG 55 89B 45 -11,-2.7 -12,-2.9 -2,-0.6 -11,-1.0 -0.700 10.7-159.9 -98.1 145.1 -12.8 5.9 6.2 67 70 A F E -E 53 0B 10 21,-2.4 2,-0.8 -2,-0.3 -14,-0.2 -0.810 31.1-100.5-119.6 155.8 -15.7 8.3 7.2 68 71 A D + 0 0 39 -16,-2.6 -16,-0.3 -2,-0.3 3,-0.3 -0.668 41.3 171.4 -73.4 113.0 -16.6 12.0 6.9 69 72 A D + 0 0 45 -2,-0.8 -1,-0.1 1,-0.2 17,-0.1 0.012 45.2 107.1-112.2 25.7 -15.7 13.3 10.4 70 73 A S S S+ 0 0 84 2,-0.0 2,-0.3 1,-0.0 -1,-0.2 0.552 90.4 20.2 -82.2 -7.2 -16.1 17.1 9.5 71 74 A Q S S- 0 0 123 -3,-0.3 2,-2.1 3,-0.1 3,-0.3 -0.931 101.2 -83.2-147.9 164.7 -19.4 17.2 11.5 72 75 A D S S+ 0 0 88 -2,-0.3 3,-0.2 1,-0.2 -22,-0.1 -0.270 74.9 132.7 -69.1 61.9 -21.1 15.0 14.3 73 76 A K S S+ 0 0 57 -2,-2.1 -23,-0.9 1,-0.3 2,-0.4 0.833 73.6 17.9 -83.7 -38.5 -22.6 12.4 11.9 74 77 A A S S+ 0 0 8 -3,-0.3 13,-2.7 -24,-0.2 2,-0.3 -0.934 83.8 168.4-143.5 110.6 -21.7 9.1 13.6 75 78 A V E -DH 47 86B 15 -28,-1.8 -28,-2.8 -2,-0.4 2,-0.4 -0.930 31.3-144.0-136.7 153.9 -20.7 9.4 17.2 76 79 A L E +DH 46 85B 0 9,-2.8 9,-2.0 -2,-0.3 2,-0.3 -0.971 31.6 157.9-115.2 132.1 -20.1 7.3 20.3 77 80 A K E +D 45 0B 90 -32,-2.2 -32,-2.8 -2,-0.4 -33,-0.1 -0.903 35.4 31.8-142.2 170.3 -21.1 8.7 23.8 78 81 A G S > S+ 0 0 21 5,-0.4 3,-2.4 3,-0.3 -2,-0.0 -0.321 72.6 81.4 77.7-163.2 -21.9 7.3 27.2 79 82 A G T 3 S- 0 0 0 -37,-0.4 -37,-1.7 1,-0.3 -1,-0.1 -0.446 121.9 -19.9 61.0-130.5 -20.5 4.3 29.0 80 83 A P T 3 S+ 0 0 38 0, 0.0 -1,-0.3 0, 0.0 2,-0.2 0.458 115.6 109.4 -82.1 -2.8 -17.1 5.4 30.4 81 84 A L < - 0 0 7 -3,-2.4 2,-0.5 -39,-0.1 -3,-0.3 -0.499 55.1-153.5 -89.4 142.7 -16.9 8.4 28.1 82 85 A D - 0 0 110 -2,-0.2 2,-0.2 -5,-0.1 -1,-0.0 -0.935 68.5 -12.7-103.5 124.6 -17.2 12.1 28.9 83 86 A G S S- 0 0 51 -2,-0.5 -5,-0.4 38,-0.1 2,-0.4 -0.509 100.5 -36.3 86.5-155.8 -18.4 14.1 25.9 84 87 A T - 0 0 35 -2,-0.2 38,-2.5 -7,-0.1 2,-0.5 -0.948 42.0-164.8-123.3 131.1 -18.7 13.2 22.2 85 88 A Y E -HI 76 121B 5 -9,-2.0 -9,-2.8 -2,-0.4 2,-0.4 -0.980 14.8-143.9-121.8 124.8 -16.4 11.0 20.1 86 89 A R E -HI 75 120B 45 34,-2.6 34,-1.9 -2,-0.5 2,-0.3 -0.734 18.1-117.8 -92.5 132.4 -16.6 11.1 16.3 87 90 A L E + I 0 119B 3 -13,-2.7 32,-0.2 -2,-0.4 -13,-0.1 -0.511 38.1 165.2 -65.2 126.8 -16.1 8.0 14.1 88 91 A I E - 0 0 36 30,-2.6 -21,-2.4 1,-0.4 2,-0.3 0.735 59.7 -25.8-109.5 -40.3 -13.1 8.5 11.8 89 92 A Q E -GI 66 118B 34 29,-1.2 29,-2.8 -23,-0.2 -1,-0.4 -0.985 47.3-142.0-164.8 159.3 -12.3 4.9 10.4 90 93 A F E +GI 65 117B 0 -25,-1.9 -25,-2.7 -2,-0.3 2,-0.3 -0.968 23.3 163.4-126.0 158.1 -12.7 1.1 11.1 91 94 A H E - I 0 116B 23 25,-1.8 25,-3.0 -2,-0.3 2,-0.3 -0.926 22.7-126.8-154.2 175.6 -10.3 -1.7 10.4 92 95 A F E - I 0 115B 0 -29,-0.5 2,-0.3 -2,-0.3 -29,-0.3 -0.864 0.9-150.0-127.4 161.6 -9.6 -5.4 11.4 93 96 A H E + I 0 114B 5 21,-2.0 21,-2.2 -2,-0.3 2,-0.3 -0.980 31.0 169.7-123.5 137.8 -6.8 -7.6 12.7 94 97 A W E - I 0 113B 0 -2,-0.3 146,-1.2 19,-0.2 145,-0.9 -0.939 22.5-120.7-149.7 170.5 -6.9 -11.4 11.7 95 98 A G - 0 0 0 17,-1.4 6,-0.1 5,-0.6 3,-0.1 -0.463 23.7-120.7-107.7 175.8 -4.9 -14.7 11.6 96 99 A S S S+ 0 0 48 -2,-0.1 2,-0.3 142,-0.1 5,-0.1 0.601 104.2 32.7 -83.5 -19.5 -3.6 -17.3 9.3 97 100 A L S > S- 0 0 109 3,-0.2 3,-1.6 15,-0.1 -2,-0.2 -0.924 91.1-109.2-136.1 157.5 -5.8 -20.0 11.0 98 101 A D T 3 S+ 0 0 70 -2,-0.3 48,-0.2 1,-0.3 15,-0.1 0.711 111.7 63.8 -67.9 -18.7 -9.2 -19.7 12.7 99 102 A G T 3 S+ 0 0 56 13,-0.1 2,-0.3 2,-0.1 11,-0.3 0.264 106.5 38.3 -87.7 12.6 -7.7 -20.2 16.2 100 103 A Q < + 0 0 52 -3,-1.6 -5,-0.6 12,-0.1 -3,-0.2 -0.979 65.3 91.2-151.8 162.0 -5.7 -16.9 16.2 101 104 A G + 0 0 0 1,-0.5 13,-0.3 -2,-0.3 11,-0.2 0.015 56.6 107.6 140.6 -31.5 -6.0 -13.3 14.9 102 105 A S - 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