==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=27-NOV-2009 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER GROWTH FACTOR/GROWTH FACTOR RECEPTOR 19-APR-00 1EV2 . COMPND 2 MOLECULE: PROTEIN (FIBROBLAST GROWTH FACTOR 2); . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR A.N.PLOTNIKOV,S.R.HUBBARD,J.SCHLESSINGER,M.MOHAMMADI . 1310 14 8 4 4 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 56851.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 808 61.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 39 3.0 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 463 35.3 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 13 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 20 1.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 22 1.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 1 0.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 7 0.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 116 8.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 138 10.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 16 1.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 13 1.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 0 2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 24 20 8 17 11 12 0 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 12 4 0 8 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 16 A H > 0 0 94 0, 0.0 3,-1.5 0, 0.0 651,-0.1 0.000 360.0 360.0 360.0 119.3 66.6 -7.6 7.4 2 17 A F T 3 + 0 0 6 1,-0.3 38,-0.2 651,-0.2 679,-0.1 0.750 360.0 58.1 -57.9 -29.8 70.3 -6.7 7.7 3 18 A K T 3 S+ 0 0 54 678,-0.1 -1,-0.3 36,-0.1 679,-0.1 0.638 85.9 98.7 -80.3 -10.0 71.5 -10.3 7.5 4 19 A D S < S- 0 0 89 -3,-1.5 36,-0.3 1,-0.1 0, 0.0 -0.453 83.2-104.1 -76.6 146.9 69.9 -10.9 4.1 5 20 A P - 0 0 33 0, 0.0 124,-0.9 0, 0.0 2,-0.3 -0.230 44.3-165.9 -64.0 159.9 72.1 -10.6 0.9 6 21 A K E -AB 38 128A 23 32,-2.8 32,-3.1 122,-0.2 2,-0.4 -0.944 24.2-124.6-147.0 166.7 71.7 -7.5 -1.2 7 22 A R E - B 0 127A 40 120,-3.0 120,-3.0 -2,-0.3 2,-0.7 -0.872 25.1-140.5-109.3 144.5 72.4 -5.8 -4.5 8 23 A L E - B 0 126A 1 -2,-0.4 9,-2.7 28,-0.4 2,-0.5 -0.919 16.5-158.4-112.6 106.5 74.2 -2.5 -4.4 9 24 A Y E -CB 16 125A 1 116,-2.1 116,-2.6 -2,-0.7 2,-0.5 -0.710 7.9-142.1 -86.6 124.3 72.7 -0.1 -7.0 10 25 A C E >> -CB 15 124A 0 5,-3.2 4,-1.3 -2,-0.5 5,-0.6 -0.771 4.5-148.5 -91.6 124.7 75.0 2.8 -8.1 11 26 A K T 45S+ 0 0 63 112,-2.8 2,-1.0 -2,-0.5 -1,-0.2 0.840 82.7 87.0 -57.1 -32.9 73.2 6.1 -8.7 12 27 A N T >45S- 0 0 29 108,-0.7 3,-0.7 111,-0.5 -2,-0.1 -0.575 122.1 -23.8 -73.2 102.5 75.8 6.8 -11.4 13 28 A G T 345S- 0 0 12 -2,-1.0 -1,-0.2 1,-0.2 -2,-0.2 0.237 101.0 -93.4 81.3 -17.1 74.3 5.2 -14.5 14 29 A G T 3<5S+ 0 0 2 -4,-1.3 2,-0.3 1,-0.2 -1,-0.2 0.891 71.8 156.7 76.6 39.3 72.2 2.7 -12.5 15 30 A F E < < -C 10 0A 16 -3,-0.7 -5,-3.2 -5,-0.6 2,-0.5 -0.751 40.2-130.0 -99.7 146.5 74.6 -0.2 -12.5 16 31 A F E -CD 9 28A 3 12,-3.6 12,-1.4 -2,-0.3 -7,-0.2 -0.818 33.5-108.4 -94.2 129.0 74.5 -3.0 -9.9 17 32 A L E - D 0 27A 1 -9,-2.7 2,-0.4 -2,-0.5 -9,-0.3 -0.360 42.2-160.6 -57.3 129.1 78.0 -3.7 -8.4 18 33 A R E - D 0 26A 45 8,-3.4 8,-1.6 -11,-0.1 2,-0.6 -0.954 17.3-163.7-122.9 134.7 79.2 -7.0 -9.8 19 34 A I E - D 0 25A 1 16,-2.7 36,-0.5 -2,-0.4 6,-0.2 -0.922 18.6-148.9-118.8 105.9 81.8 -9.4 -8.5 20 35 A H > - 0 0 38 4,-2.4 3,-2.3 -2,-0.6 49,-0.1 -0.325 24.2-113.7 -71.5 152.5 83.0 -12.0 -11.0 21 36 A P T 3 S+ 0 0 79 0, 0.0 -1,-0.1 0, 0.0 31,-0.0 0.805 117.4 53.0 -55.4 -32.6 84.2 -15.5 -10.2 22 37 A D T 3 S- 0 0 135 2,-0.1 47,-0.1 35,-0.0 -2,-0.1 0.343 125.1 -99.9 -88.0 7.4 87.7 -14.7 -11.3 23 38 A G S < S+ 0 0 12 -3,-2.3 46,-1.9 1,-0.3 2,-0.2 0.506 74.2 140.1 92.1 4.0 87.9 -11.6 -9.1 24 39 A R - 0 0 42 44,-0.2 -4,-2.4 -5,-0.0 2,-0.5 -0.570 37.8-148.6 -82.0 146.7 87.1 -8.8 -11.6 25 40 A V E +D 19 0A 7 42,-0.5 84,-0.6 -2,-0.2 2,-0.2 -0.965 35.0 121.2-123.4 126.5 84.9 -5.9 -10.5 26 41 A D E -DE 18 108A 19 -8,-1.6 -8,-3.4 -2,-0.5 2,-0.3 -0.836 48.9 -95.7-155.9-168.1 82.5 -3.9 -12.6 27 42 A G E -D 17 0A 6 80,-2.8 2,-0.3 -2,-0.2 -10,-0.2 -0.890 27.7-178.6-126.0 155.6 78.8 -2.9 -12.9 28 43 A V E -D 16 0A 24 -12,-1.4 -12,-3.6 -2,-0.3 79,-0.1 -0.986 26.1-142.9-149.4 153.9 75.8 -4.2 -14.9 29 44 A R + 0 0 95 -2,-0.3 2,-0.9 -14,-0.2 -1,-0.1 0.682 68.9 105.2 -93.0 -19.4 72.2 -3.2 -15.3 30 45 A E > - 0 0 61 1,-0.2 3,-2.1 -14,-0.1 -2,-0.0 -0.488 55.1-160.3 -69.0 104.5 70.7 -6.7 -15.6 31 46 A K T 3 S+ 0 0 48 -2,-0.9 -1,-0.2 1,-0.3 5,-0.1 0.631 87.6 64.7 -58.5 -12.5 69.0 -7.4 -12.3 32 47 A S T 3 + 0 0 93 3,-0.0 -1,-0.3 2,-0.0 -2,-0.1 0.626 68.8 120.9 -88.3 -14.3 69.1 -11.1 -13.1 33 48 A D X - 0 0 25 -3,-2.1 3,-1.1 1,-0.2 4,-0.1 -0.283 58.1-146.0 -54.8 125.8 72.9 -11.4 -13.1 34 49 A P T 3 S+ 0 0 77 0, 0.0 3,-0.5 0, 0.0 20,-0.4 0.583 91.1 66.3 -70.9 -9.8 73.9 -14.0 -10.5 35 50 A H T 3 S+ 0 0 44 1,-0.2 -16,-2.7 19,-0.1 -2,-0.1 0.204 85.9 66.9 -99.6 17.0 77.1 -12.1 -9.6 36 51 A I < + 0 0 0 -3,-1.1 2,-0.8 -18,-0.2 -28,-0.4 0.370 69.2 107.9-112.0 0.1 75.5 -9.0 -8.1 37 52 A K - 0 0 89 -3,-0.5 16,-2.0 -4,-0.1 17,-0.5 -0.720 55.2-175.3 -80.6 112.1 74.1 -10.8 -5.1 38 53 A L E -AF 6 52A 0 -32,-3.1 -32,-2.8 -2,-0.8 2,-0.5 -0.752 25.2-144.9-113.8 159.5 76.3 -9.6 -2.2 39 54 A Q E - F 0 51A 57 12,-2.3 12,-2.2 -2,-0.3 2,-0.3 -0.953 15.1-161.8-124.5 111.4 76.6 -10.3 1.5 40 55 A L E + F 0 50A 3 -2,-0.5 2,-0.3 -36,-0.3 10,-0.2 -0.646 10.9 178.7 -90.8 150.0 77.6 -7.5 3.8 41 56 A Q E - F 0 49A 10 8,-1.5 8,-2.2 -2,-0.3 2,-0.3 -0.939 25.4-127.7-153.7 126.6 79.0 -8.2 7.3 42 57 A A E - F 0 48A 0 615,-0.4 6,-0.3 -2,-0.3 617,-0.2 -0.571 18.7-177.7 -77.2 135.8 80.1 -5.7 10.0 43 58 A E E S- 0 0 57 4,-2.5 2,-0.3 1,-0.5 5,-0.2 0.696 75.9 -14.1-101.2 -29.4 83.6 -6.3 11.4 44 59 A E E > S- F 0 47A 94 3,-1.1 3,-2.7 632,-0.0 -1,-0.5 -0.934 106.9 -43.9-160.5 170.2 83.3 -3.5 13.9 45 60 A R T 3 S- 0 0 131 -2,-0.3 661,-0.2 1,-0.3 3,-0.1 -0.163 126.8 -6.4 -47.5 119.7 81.0 -0.5 14.4 46 61 A G T 3 S+ 0 0 8 610,-0.4 35,-2.5 659,-0.4 2,-0.4 0.544 111.7 106.9 71.8 7.0 80.4 1.2 11.0 47 62 A V E < +FG 44 80A 0 -3,-2.7 -4,-2.5 33,-0.2 -3,-1.1 -0.971 44.5 176.1-122.0 129.3 82.9 -1.0 9.2 48 63 A V E -FG 42 79A 0 31,-2.8 31,-2.8 -2,-0.4 2,-0.4 -0.861 26.1-140.5-130.8 164.8 81.9 -3.8 6.8 49 64 A S E -F 41 0A 2 -8,-2.2 -8,-1.5 -2,-0.3 2,-0.5 -0.899 21.0-144.7-116.5 147.6 83.3 -6.4 4.3 50 65 A I E -F 40 0A 1 27,-0.5 9,-3.3 -2,-0.4 2,-0.5 -0.960 16.8-170.4-120.6 116.0 81.4 -7.0 1.1 51 66 A K E -FH 39 58A 54 -12,-2.2 -12,-2.3 -2,-0.5 2,-0.7 -0.897 22.6-133.7-114.5 129.3 81.4 -10.6 -0.3 52 67 A G E >> -FH 38 57A 2 5,-2.6 4,-1.6 -2,-0.5 5,-0.9 -0.661 17.3-153.4 -75.8 115.9 80.1 -11.8 -3.7 53 68 A V T 45S+ 0 0 61 -16,-2.0 -1,-0.2 -2,-0.7 -15,-0.1 0.938 90.4 38.8 -56.8 -51.8 78.0 -14.8 -2.9 54 69 A S T 45S+ 0 0 65 -17,-0.5 -1,-0.2 -20,-0.4 -19,-0.1 0.969 120.4 43.0 -64.1 -56.2 78.5 -16.6 -6.3 55 70 A A T 45S- 0 0 16 -36,-0.5 -1,-0.2 2,-0.1 -2,-0.2 0.693 96.8-142.5 -64.0 -18.8 82.2 -15.7 -6.8 56 71 A N T <5 + 0 0 102 -4,-1.6 2,-0.3 1,-0.2 -3,-0.2 0.881 59.6 122.4 54.9 40.2 82.8 -16.5 -3.1 57 72 A R E < -H 52 0A 7 -5,-0.9 -5,-2.6 -38,-0.1 2,-0.4 -0.885 61.1-120.7-129.9 160.6 85.3 -13.6 -3.0 58 73 A Y E -HI 51 70A 33 12,-3.1 12,-3.0 -2,-0.3 -7,-0.2 -0.881 27.6-116.1-107.4 131.4 85.6 -10.4 -0.9 59 74 A L E + I 0 69A 0 -9,-3.3 -9,-0.3 -2,-0.4 2,-0.3 -0.312 42.6 174.8 -61.3 143.0 85.7 -6.9 -2.5 60 75 A A E - I 0 68A 6 8,-2.5 8,-2.2 -11,-0.1 2,-0.5 -0.995 28.9-140.1-152.1 153.3 89.0 -5.1 -1.9 61 76 A M E - I 0 67A 1 15,-1.9 6,-0.2 -2,-0.3 35,-0.1 -0.978 24.0-145.5-119.5 122.3 90.7 -1.9 -2.9 62 77 A K > - 0 0 30 4,-2.6 3,-1.8 -2,-0.5 50,-0.1 -0.191 31.6 -95.7 -79.3 172.2 94.4 -2.0 -3.7 63 78 A E T 3 S+ 0 0 81 1,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.779 124.1 53.2 -59.7 -30.1 97.2 0.6 -3.1 64 79 A D T 3 S- 0 0 119 2,-0.1 49,-0.3 48,-0.0 -1,-0.3 0.402 123.4-103.0 -87.6 3.5 96.8 2.1 -6.6 65 80 A G S < S+ 0 0 6 -3,-1.8 47,-3.0 1,-0.3 2,-0.2 0.593 74.7 141.4 87.9 12.2 93.1 2.5 -6.1 66 81 A R - 0 0 18 45,-0.2 -4,-2.6 46,-0.1 2,-0.4 -0.578 44.9-131.4 -87.9 150.5 92.0 -0.5 -8.2 67 82 A L E +I 61 0A 9 -6,-0.2 -42,-0.5 -2,-0.2 2,-0.3 -0.836 36.5 147.0-105.4 140.8 89.1 -2.7 -7.2 68 83 A L E -I 60 0A 76 -8,-2.2 -8,-2.5 -2,-0.4 2,-0.5 -0.952 42.2-112.1-158.0 168.8 89.2 -6.5 -7.2 69 84 A A E -I 59 0A 11 -46,-1.9 -10,-0.3 -2,-0.3 2,-0.3 -0.957 29.1-151.5-118.2 120.3 87.7 -9.5 -5.2 70 85 A S E -I 58 0A 29 -12,-3.0 -12,-3.1 -2,-0.5 -47,-0.1 -0.627 17.5-140.4 -93.9 145.3 90.0 -11.6 -3.0 71 86 A K S S+ 0 0 87 -2,-0.3 2,-0.4 -14,-0.2 -1,-0.1 0.900 93.8 36.6 -65.9 -41.8 89.6 -15.3 -2.1 72 87 A S S S- 0 0 79 -14,-0.1 2,-0.2 -15,-0.1 -1,-0.1 -0.882 96.2-100.9-117.1 149.1 90.7 -14.6 1.4 73 88 A V + 0 0 45 -2,-0.4 2,-0.2 2,-0.1 -13,-0.1 -0.439 44.4 169.0 -68.7 129.1 90.1 -11.6 3.6 74 89 A T > - 0 0 66 -2,-0.2 3,-1.8 -16,-0.0 -4,-0.1 -0.760 52.9 -89.5-129.6 177.3 92.8 -9.0 3.9 75 90 A D T 3 S+ 0 0 116 1,-0.3 3,-0.5 -2,-0.2 20,-0.2 0.545 121.8 65.4 -67.6 -5.8 93.0 -5.5 5.4 76 91 A E T 3 S+ 0 0 16 1,-0.2 -15,-1.9 19,-0.1 -1,-0.3 0.263 87.0 72.8 -97.3 10.0 92.0 -4.1 2.0 77 92 A C S < S+ 0 0 0 -3,-1.8 -27,-0.5 -17,-0.2 2,-0.4 0.279 77.3 90.7-107.9 10.3 88.6 -5.7 2.3 78 93 A F - 0 0 15 -3,-0.5 16,-2.4 -29,-0.1 17,-0.5 -0.916 50.0-178.0-114.6 134.6 87.1 -3.4 5.0 79 94 A F E -GJ 48 93A 0 -31,-2.8 -31,-2.8 -2,-0.4 2,-0.4 -0.981 31.2-118.2-134.4 139.1 85.0 -0.2 4.3 80 95 A F E -GJ 47 92A 67 12,-3.5 12,-2.2 -2,-0.4 2,-0.5 -0.593 33.3-149.7 -71.0 123.6 83.4 2.5 6.5 81 96 A E E + J 0 91A 7 -35,-2.5 2,-0.4 -2,-0.4 10,-0.2 -0.867 20.2 177.6 -99.7 129.7 79.7 2.3 5.6 82 97 A R E - J 0 90A 126 8,-1.9 8,-1.7 -2,-0.5 2,-0.8 -0.995 29.0-142.4-137.2 133.9 77.8 5.6 5.9 83 98 A L E - J 0 89A 20 -2,-0.4 6,-0.2 6,-0.2 2,-0.1 -0.849 33.1-145.7 -91.3 111.0 74.2 6.6 5.3 84 99 A E > - 0 0 39 4,-2.7 3,-2.5 -2,-0.8 4,-0.0 -0.319 24.4-105.2 -76.7 163.2 74.5 10.1 3.8 85 100 A S T 3 S+ 0 0 71 1,-0.3 1141,-0.2 2,-0.1 -1,-0.1 0.745 121.8 61.7 -58.6 -24.2 72.0 13.0 4.3 86 101 A N T 3 S- 0 0 58 2,-0.1 -1,-0.3 1223,-0.0 3,-0.1 0.444 118.6-113.4 -81.4 0.2 70.8 12.3 0.7 87 102 A N S < S+ 0 0 18 -3,-2.5 2,-0.3 1,-0.3 -2,-0.1 0.653 80.2 114.6 75.4 19.0 69.8 8.8 1.8 88 103 A Y - 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