==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 08-NOV-05 2EXB . COMPND 2 MOLECULE: PENICILLIN-BINDING PROTEIN 4; . SOURCE 2 ORGANISM_SCIENTIFIC: ESCHERICHIA COLI; . AUTHOR H.KISHIDA,S.UNZAI,D.I.ROPER,A.LLOYD,S.-Y.PARK,J.R.H.TAME . 446 2 2 2 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 19909.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 323 72.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 29 6.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 74 16.6 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 2 0.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 1 0.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 40 9.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 52 11.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 103 23.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 7 1.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 1 1 0 0 0 0 0 1 1 2 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 1 1 1 2 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 4 0 1 1 0 4 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 24 A D 0 0 155 0, 0.0 4,-0.4 0, 0.0 28,-0.0 0.000 360.0 360.0 360.0 -55.2 69.6 -25.3 48.6 2 25 A E > + 0 0 145 2,-0.1 3,-0.6 1,-0.1 4,-0.2 0.858 360.0 54.3 -73.1 -37.7 70.6 -27.7 45.8 3 26 A Y G > S+ 0 0 42 1,-0.2 3,-3.3 2,-0.2 4,-0.3 0.891 92.7 67.7 -64.3 -45.1 72.9 -24.9 44.4 4 27 A I G > S+ 0 0 39 1,-0.3 3,-2.2 2,-0.2 -1,-0.2 0.794 88.7 67.8 -48.1 -36.1 74.9 -24.3 47.6 5 28 A T G < S+ 0 0 117 -3,-0.6 -1,-0.3 -4,-0.4 -2,-0.2 0.690 85.6 71.5 -58.4 -21.6 76.4 -27.8 47.3 6 29 A Q G < S+ 0 0 66 -3,-3.3 -1,-0.3 -4,-0.2 -2,-0.2 0.672 91.4 74.5 -66.9 -18.5 78.2 -26.5 44.1 7 30 A L S < S- 0 0 18 -3,-2.2 418,-0.0 -4,-0.3 425,-0.0 -0.658 94.4 -93.6-101.2 152.4 80.5 -24.4 46.4 8 31 A P > - 0 0 29 0, 0.0 3,-1.2 0, 0.0 -1,-0.1 -0.223 34.7-122.6 -48.8 148.8 83.5 -25.3 48.6 9 32 A A T 3 S+ 0 0 110 1,-0.2 -2,-0.0 -4,-0.1 -4,-0.0 0.708 107.2 72.1 -75.8 -15.7 82.4 -25.9 52.3 10 33 A G T 3 S+ 0 0 68 2,-0.1 2,-0.3 414,-0.0 -1,-0.2 0.583 84.0 99.8 -68.4 -9.6 84.8 -23.2 53.4 11 34 A A < - 0 0 26 -3,-1.2 2,-0.7 414,-0.1 413,-0.2 -0.592 63.5-144.5 -98.0 144.3 82.5 -20.6 51.9 12 35 A N E -A 423 0A 67 411,-1.7 411,-2.1 -2,-0.3 2,-0.4 -0.874 19.0-173.8-106.9 107.4 79.9 -18.3 53.4 13 36 A L E +A 422 0A 12 -2,-0.7 2,-0.4 409,-0.2 409,-0.2 -0.900 11.8 173.6-104.2 131.5 76.8 -17.6 51.3 14 37 A A E +A 421 0A 0 407,-2.7 407,-3.2 -2,-0.4 2,-0.4 -0.991 20.2 173.7-129.7 122.5 74.0 -15.1 52.3 15 38 A L E +AB 420 29A 6 14,-2.8 14,-3.3 -2,-0.4 2,-0.4 -0.995 18.5 176.5-141.7 135.2 71.5 -14.7 49.5 16 39 A M E -AB 419 28A 17 403,-2.3 403,-2.6 -2,-0.4 2,-0.4 -0.999 2.0-179.5-139.6 132.4 68.1 -12.9 49.0 17 40 A V E +AB 418 27A 1 10,-2.5 9,-2.2 -2,-0.4 10,-1.7 -0.989 12.7 168.5-131.4 126.9 66.0 -12.8 45.7 18 41 A Q E -A 417 0A 22 399,-2.9 399,-3.4 -2,-0.4 3,-0.1 -0.993 36.8-114.5-145.6 131.7 62.8 -10.8 45.7 19 42 A K E > -A 416 0A 110 5,-0.4 3,-1.8 -2,-0.4 397,-0.3 -0.300 53.4 -91.6 -54.4 140.8 60.4 -9.7 43.0 20 43 A V T 3 S+ 0 0 43 395,-2.8 -1,-0.1 1,-0.3 395,-0.1 -0.467 111.3 5.8 -64.4 126.3 60.3 -5.9 42.8 21 44 A G T 3 S+ 0 0 63 1,-0.3 -1,-0.3 -2,-0.2 2,-0.1 0.344 96.3 136.0 85.8 -6.3 57.5 -4.7 45.1 22 45 A A < - 0 0 31 -3,-1.8 -1,-0.3 1,-0.1 -4,-0.0 -0.371 55.3-138.7 -74.1 153.9 56.7 -8.2 46.5 23 46 A S S S+ 0 0 132 1,-0.1 -1,-0.1 -3,-0.1 -2,-0.0 0.698 85.5 40.9 -86.6 -17.3 56.1 -8.6 50.2 24 47 A A S S- 0 0 66 -5,-0.0 -5,-0.4 0, 0.0 2,-0.1 -0.975 82.9-113.4-136.4 145.2 58.0 -11.8 50.4 25 48 A P - 0 0 46 0, 0.0 -7,-0.3 0, 0.0 3,-0.1 -0.437 5.0-147.8 -77.2 150.2 61.3 -13.2 48.9 26 49 A A S S+ 0 0 60 -9,-2.2 2,-0.4 1,-0.3 -8,-0.2 0.774 94.1 24.7 -79.5 -35.0 61.6 -16.0 46.3 27 50 A I E +B 17 0A 39 -10,-1.7 -10,-2.5 2,-0.0 2,-0.4 -0.998 67.7 172.6-132.9 129.4 64.9 -17.1 47.8 28 51 A D E +B 16 0A 87 -2,-0.4 2,-0.5 -12,-0.2 -12,-0.2 -0.867 7.0 161.6-142.1 104.9 66.0 -16.4 51.3 29 52 A Y E S-B 15 0A 66 -14,-3.3 -14,-2.8 -2,-0.4 4,-0.0 -0.880 78.8 -35.3-133.5 102.0 69.2 -17.9 52.6 30 53 A H S > S+ 0 0 101 -2,-0.5 3,-1.3 -16,-0.2 -14,-0.1 0.846 82.9 159.7 52.7 40.7 70.8 -16.4 55.7 31 54 A S T 3 + 0 0 2 -16,-0.3 314,-3.0 1,-0.3 315,-0.3 0.656 65.8 53.5 -67.7 -19.2 69.6 -13.1 54.4 32 55 A Q T 3 S+ 0 0 160 312,-0.2 2,-0.4 311,-0.1 -1,-0.3 0.531 83.0 108.8 -92.4 -5.8 69.8 -11.4 57.9 33 56 A Q S < S- 0 0 72 -3,-1.3 2,-0.2 1,-0.1 312,-0.1 -0.586 72.6-124.3 -77.5 127.0 73.4 -12.4 58.3 34 57 A M + 0 0 74 -2,-0.4 309,-0.3 309,-0.2 2,-0.3 -0.423 35.0 176.8 -77.5 137.7 75.8 -9.5 58.0 35 58 A A B -F 342 0B 15 307,-3.0 307,-2.5 -2,-0.2 387,-0.0 -0.904 40.7 -91.7-136.8 160.6 78.6 -9.6 55.5 36 59 A L - 0 0 46 -2,-0.3 305,-0.2 305,-0.2 302,-0.1 -0.679 35.9-165.5 -66.9 118.0 81.5 -7.5 54.0 37 60 A P > - 0 0 0 0, 0.0 3,-1.6 0, 0.0 -1,-0.1 0.738 12.8-176.8 -80.3 -23.6 79.8 -5.7 51.0 38 61 A A G > S- 0 0 4 299,-0.3 3,-2.3 1,-0.2 4,-0.2 -0.301 71.0 -7.1 48.5-139.6 83.1 -4.6 49.4 39 62 A S G > S+ 0 0 20 1,-0.3 3,-1.9 2,-0.2 -1,-0.2 0.620 120.0 79.6 -68.3 -10.1 82.3 -2.5 46.2 40 63 A T G X> S+ 0 0 0 -3,-1.6 3,-1.6 1,-0.3 4,-0.7 0.717 76.8 79.4 -63.8 -14.9 78.5 -3.2 46.4 41 64 A Q H X> S+ 0 0 0 -3,-2.3 4,-1.9 1,-0.3 3,-0.6 0.873 77.0 71.6 -54.9 -33.7 78.8 -0.4 49.1 42 65 A K H <> S+ 0 0 0 -3,-1.9 4,-2.8 292,-0.4 -1,-0.3 0.729 86.0 64.6 -57.7 -24.3 78.8 1.9 46.0 43 66 A V H <> S+ 0 0 0 -3,-1.6 4,-2.4 -4,-0.2 -1,-0.2 0.964 106.3 41.8 -61.1 -50.6 75.1 1.2 45.4 44 67 A I H S+ 0 0 0 -4,-2.5 4,-2.8 -5,-0.3 5,-1.4 0.913 108.0 48.9 -65.0 -47.5 74.4 11.0 46.8 50 73 A L H <5S+ 0 0 14 -4,-2.5 4,-0.4 3,-0.2 -1,-0.2 0.911 115.7 44.8 -60.2 -42.9 71.5 11.4 44.3 51 74 A I H <5S+ 0 0 48 -4,-2.2 -2,-0.2 -5,-0.2 -1,-0.2 0.942 124.2 32.1 -67.6 -45.2 69.1 12.1 47.2 52 75 A Q H <5S+ 0 0 47 -4,-2.8 -3,-0.2 -5,-0.2 -2,-0.2 0.946 136.1 19.6 -80.3 -48.0 71.3 14.5 49.0 53 76 A L T <5S- 0 0 29 -4,-2.8 -3,-0.2 -5,-0.3 3,-0.2 0.772 99.9-136.7 -96.4 -29.2 73.4 16.2 46.3 54 77 A G > < - 0 0 15 -5,-1.4 3,-1.5 -4,-0.4 218,-0.2 0.162 30.7 -76.7 81.6 159.4 71.2 15.6 43.3 55 78 A P T 3 S+ 0 0 59 0, 0.0 218,-2.7 0, 0.0 219,-0.3 0.681 127.2 54.7 -65.6 -18.8 72.1 14.5 39.8 56 79 A D T 3 S+ 0 0 120 216,-0.2 -2,-0.1 215,-0.2 -6,-0.0 0.447 74.8 124.6 -99.5 -3.5 73.3 18.0 38.8 57 80 A F < - 0 0 52 -3,-1.5 215,-2.5 -4,-0.1 2,-0.4 -0.278 40.6-167.4 -49.5 138.9 75.9 18.5 41.7 58 81 A R - 0 0 104 213,-0.2 2,-0.1 214,-0.1 212,-0.1 -0.997 22.2-120.0-130.5 138.7 79.3 19.4 40.4 59 82 A F - 0 0 1 211,-0.4 210,-1.8 -2,-0.4 2,-0.4 -0.474 35.3-148.4 -67.9 151.7 82.6 19.4 42.5 60 83 A T E -G 268 0C 55 23,-0.3 2,-0.4 208,-0.2 208,-0.2 -0.984 21.2-176.8-133.9 134.8 84.2 22.9 42.5 61 84 A T E -G 267 0C 4 206,-2.7 206,-2.1 -2,-0.4 2,-0.3 -0.985 18.8-178.8-123.2 137.2 87.7 24.2 42.6 62 85 A T E -GH 266 81C 11 19,-2.2 19,-2.3 -2,-0.4 2,-0.5 -0.950 30.6-143.2-135.6 154.8 88.5 27.9 42.7 63 86 A L E -GH 265 80C 5 202,-2.3 201,-2.7 -2,-0.3 202,-1.6 -0.993 34.3-177.3-107.4 125.2 91.2 30.6 42.8 64 87 A E E -GH 263 79C 4 15,-2.8 15,-3.4 -2,-0.5 2,-0.4 -0.936 19.1-143.4-124.4 145.0 90.1 33.4 45.1 65 88 A T E -GH 262 78C 10 197,-1.8 197,-2.4 -2,-0.3 2,-0.5 -0.919 6.0-167.1-109.1 133.5 91.7 36.7 46.0 66 89 A K E + H 0 77C 64 11,-2.1 11,-1.3 -2,-0.4 2,-0.2 -0.930 63.7 31.0-114.8 97.6 91.4 38.2 49.5 67 90 A G E S- H 0 76C 42 -2,-0.5 2,-0.3 9,-0.2 9,-0.2 -0.755 93.4 -56.2 140.6 171.5 92.6 41.8 49.1 68 91 A N E - H 0 75C 137 7,-0.8 7,-2.8 -2,-0.2 2,-0.8 -0.665 39.2-135.5 -86.6 137.8 92.9 44.8 46.7 69 92 A V E + H 0 74C 75 -2,-0.3 2,-0.6 5,-0.2 5,-0.2 -0.835 28.7 178.0 -95.0 107.1 94.5 44.5 43.3 70 93 A E E > - H 0 73C 145 3,-2.7 3,-1.2 -2,-0.8 -2,-0.0 -0.927 67.1 -23.4-112.5 110.6 96.8 47.6 42.8 71 94 A N T 3 S- 0 0 157 -2,-0.6 -1,-0.2 1,-0.3 3,-0.1 0.910 128.1 -46.7 64.1 40.9 98.9 47.9 39.7 72 95 A G T 3 S+ 0 0 12 1,-0.2 34,-2.9 -3,-0.1 35,-1.6 0.501 117.3 116.6 77.2 6.2 98.9 44.2 39.0 73 96 A V E < -Hi 70 107C 33 -3,-1.2 -3,-2.7 33,-0.2 2,-0.6 -0.926 58.9-145.0-113.7 119.9 99.8 43.5 42.6 74 97 A L E -Hi 69 108C 0 33,-3.0 35,-3.4 -2,-0.5 2,-1.2 -0.748 9.1-154.1 -79.8 119.0 97.4 41.6 45.0 75 98 A K E S+Hi 68 109C 131 -7,-2.8 -7,-0.8 -2,-0.6 2,-0.3 -0.807 71.8 19.8 -95.7 92.9 97.8 43.1 48.4 76 99 A G E S-H 67 0C 17 -2,-1.2 2,-0.3 33,-1.1 -9,-0.2 -0.972 102.6 -30.7 142.8-158.8 96.7 40.0 50.3 77 100 A D E -H 66 0C 46 -11,-1.3 -11,-2.1 -2,-0.3 2,-0.5 -0.711 34.8-138.6-104.2 144.9 96.5 36.3 49.8 78 101 A L E -Hj 65 112C 0 33,-2.1 35,-3.7 -2,-0.3 2,-0.5 -0.900 25.9-159.3 -87.7 129.8 95.8 34.0 46.9 79 102 A V E -Hj 64 113C 0 -15,-3.4 -15,-2.8 -2,-0.5 2,-0.8 -0.949 11.9-164.5-114.8 119.2 93.5 31.2 48.0 80 103 A A E -Hj 63 114C 1 33,-3.4 35,-2.5 -2,-0.5 2,-0.9 -0.918 16.0-161.5 -99.8 106.2 93.3 28.0 46.0 81 104 A R E -Hj 62 115C 46 -19,-2.3 -19,-2.2 -2,-0.8 2,-0.2 -0.803 3.7-159.2 -97.1 105.7 90.1 26.4 47.4 82 105 A F - 0 0 6 33,-2.3 36,-0.4 -2,-0.9 62,-0.2 -0.536 10.6-168.8 -82.4 151.7 90.0 22.7 46.7 83 106 A G - 0 0 8 60,-0.3 -23,-0.3 -2,-0.2 61,-0.1 0.051 50.0 -97.4-134.9 25.7 86.7 20.9 46.7 84 107 A A + 0 0 0 59,-2.1 60,-0.1 1,-0.2 210,-0.1 0.665 57.4 172.8 70.4 19.9 87.5 17.2 46.5 85 108 A D > - 0 0 3 58,-0.4 3,-1.0 1,-0.2 -1,-0.2 -0.512 20.4-159.6 -61.9 113.9 87.0 17.1 42.8 86 109 A P T 3 S+ 0 0 0 0, 0.0 62,-0.3 0, 0.0 -1,-0.2 0.600 87.4 52.3 -70.2 -12.7 88.2 13.5 41.9 87 110 A T T 3 S+ 0 0 33 60,-0.1 -2,-0.1 183,-0.1 2,-0.1 0.358 74.5 130.7-111.1 2.5 88.7 14.5 38.2 88 111 A L < - 0 0 1 -3,-1.0 59,-2.7 57,-0.1 60,-0.5 -0.328 40.4-159.5 -57.5 134.1 90.8 17.6 38.6 89 112 A K >> - 0 0 109 57,-0.2 3,-1.2 58,-0.1 4,-1.2 -0.822 30.2-113.4-118.1 156.5 93.9 17.5 36.4 90 113 A R H >> S+ 0 0 72 -2,-0.3 4,-2.3 1,-0.3 3,-0.6 0.898 119.1 57.2 -45.0 -46.4 97.4 19.4 36.4 91 114 A Q H 3> S+ 0 0 136 1,-0.2 4,-2.2 2,-0.2 -1,-0.3 0.833 99.8 58.6 -63.5 -28.3 96.3 21.1 33.2 92 115 A D H <> S+ 0 0 23 -3,-1.2 4,-2.3 2,-0.2 -1,-0.2 0.854 106.4 47.5 -64.9 -36.1 93.2 22.5 35.0 93 116 A I H S+ 0 0 0 -4,-2.0 5,-1.4 2,-0.2 3,-0.2 0.955 112.3 43.8 -57.9 -52.3 94.4 34.6 37.3 101 124 A K H ><5S+ 0 0 67 -4,-2.4 3,-3.0 1,-0.2 -2,-0.2 0.959 110.3 54.9 -57.2 -54.2 97.2 36.2 35.3 102 125 A K H 3<5S+ 0 0 187 -4,-2.6 -1,-0.2 1,-0.3 -2,-0.2 0.801 98.4 64.0 -53.2 -31.7 94.8 37.3 32.5 103 126 A S T 3<5S- 0 0 69 -4,-1.6 -1,-0.3 -3,-0.2 -2,-0.2 0.489 128.8 -94.8 -71.3 -2.6 92.7 39.0 35.2 104 127 A G T < 5S+ 0 0 32 -3,-3.0 2,-0.7 1,-0.2 -3,-0.2 0.494 80.9 135.5 104.6 5.0 95.7 41.4 35.8 105 128 A V < + 0 0 2 -5,-1.4 -1,-0.2 -4,-0.2 -32,-0.2 -0.797 8.5 152.4 -90.4 113.8 97.5 39.7 38.8 106 129 A N + 0 0 72 -34,-2.9 140,-1.5 -2,-0.7 2,-0.3 0.510 67.5 28.0-106.5 -18.3 101.3 39.6 38.2 107 130 A Q E -ik 73 246C 81 -35,-1.6 -33,-3.0 138,-0.2 2,-0.5 -0.999 60.3-147.4-152.3 140.7 102.3 39.6 41.8 108 131 A I E -ik 74 247C 0 138,-3.0 140,-2.0 -2,-0.3 2,-1.6 -0.950 3.6-163.4-115.3 116.2 101.0 38.5 45.2 109 132 A D E S+i 75 0C 65 -35,-3.4 -33,-1.1 -2,-0.5 2,-0.3 -0.636 75.6 28.7 -91.4 75.0 102.1 40.6 48.2 110 133 A G S S- 0 0 14 -2,-1.6 139,-2.0 -35,-0.1 138,-0.2 -0.977 99.0 -38.9 163.8-163.2 101.1 37.8 50.6 111 134 A N - 0 0 48 -2,-0.3 -33,-2.1 138,-0.2 2,-0.6 -0.571 38.2-129.9 -99.0 158.6 100.7 34.1 51.0 112 135 A V E -jl 78 251C 0 138,-2.2 140,-2.4 -2,-0.2 2,-0.5 -0.958 31.2-154.9-107.6 119.6 99.5 31.4 48.7 113 136 A L E -jl 79 252C 14 -35,-3.7 -33,-3.4 -2,-0.6 2,-0.9 -0.814 14.2-156.0-105.8 129.3 96.9 29.4 50.6 114 137 A I E -jl 80 253C 7 138,-3.1 140,-2.9 -2,-0.5 2,-0.7 -0.872 22.4-159.3-102.2 100.7 96.0 25.8 49.9 115 138 A D E +jl 81 254C 0 -35,-2.5 -33,-2.3 -2,-0.9 140,-0.2 -0.746 31.2 159.0 -94.3 119.1 92.6 25.6 51.3 116 139 A T > + 0 0 4 138,-2.5 3,-1.9 -2,-0.7 139,-0.2 0.079 33.1 125.9-119.7 20.3 91.2 22.2 52.2 117 140 A S T 3 + 0 0 8 137,-0.6 140,-0.1 1,-0.3 -1,-0.1 0.589 55.1 79.4 -62.5 -16.5 88.5 23.4 54.7 118 141 A I T 3 S+ 0 0 31 -36,-0.4 186,-3.0 185,-0.1 -1,-0.3 0.828 104.9 30.1 -54.2 -34.4 85.8 21.6 52.8 119 142 A F B < S-m 304 0D 8 -3,-1.9 2,-0.3 184,-0.3 186,-0.2 -0.771 71.1-171.3-121.7 162.0 87.0 18.4 54.6 120 143 A A + 0 0 42 184,-2.3 186,-0.2 -2,-0.3 -3,-0.0 -0.973 45.5 27.6-148.8 171.2 88.6 17.7 58.0 121 144 A S S S- 0 0 88 -2,-0.3 -2,-0.0 184,-0.1 183,-0.0 -0.210 103.7 -9.7 69.3-165.0 90.3 14.9 59.9 122 145 A H - 0 0 137 1,-0.1 184,-0.2 2,-0.1 -2,-0.1 -0.261 50.0-140.9 -68.7 151.0 92.0 12.0 58.2 123 146 A D S S+ 0 0 31 103,-0.1 2,-0.4 2,-0.1 -1,-0.1 0.277 86.0 74.1 -87.8 4.9 91.9 11.4 54.4 124 147 A K S S- 0 0 91 16,-0.2 182,-0.1 4,-0.0 -2,-0.1 -0.987 83.6-125.4-122.4 130.8 91.7 7.6 55.0 125 148 A A > - 0 0 7 -2,-0.4 3,-1.4 1,-0.1 207,-0.1 -0.378 35.8 -91.4 -68.8 154.6 88.5 6.0 56.3 126 149 A P T 3 S+ 0 0 66 0, 0.0 213,-0.4 0, 0.0 -1,-0.1 -0.361 111.2 31.4 -59.5 139.6 88.5 3.8 59.4 127 150 A G T 3 S+ 0 0 21 1,-0.3 211,-2.5 210,-0.2 213,-0.1 0.479 79.3 138.4 90.5 -1.2 89.1 0.1 58.6 128 151 A W < - 0 0 30 -3,-1.4 -1,-0.3 209,-0.2 209,-0.1 -0.693 61.5-112.0 -74.0 132.2 91.3 0.6 55.5 129 152 A P > - 0 0 29 0, 0.0 3,-1.1 0, 0.0 4,-0.3 -0.387 19.9-138.0 -62.9 130.2 94.3 -1.9 55.5 130 153 A W G > S+ 0 0 197 1,-0.2 3,-1.9 2,-0.2 4,-0.3 0.863 96.9 63.5 -57.3 -38.1 97.5 0.1 56.0 131 154 A N G 3 S+ 0 0 91 1,-0.3 3,-0.3 2,-0.1 -1,-0.2 0.675 99.3 53.7 -69.9 -16.1 99.5 -1.9 53.4 132 155 A D G X S+ 0 0 27 -3,-1.1 3,-1.9 1,-0.2 6,-0.4 0.496 79.6 95.6 -91.5 -3.1 97.2 -0.6 50.5 133 156 A M T < S+ 0 0 35 -3,-1.9 -1,-0.2 1,-0.3 -2,-0.1 0.775 84.5 49.4 -66.2 -27.2 97.7 3.1 51.4 134 157 A T T 3 S+ 0 0 14 -4,-0.3 90,-2.4 -3,-0.3 2,-0.3 0.492 93.0 95.5 -86.2 -4.6 100.5 3.5 48.8 135 158 A Q S X S- 0 0 81 -3,-1.9 3,-1.8 88,-0.2 88,-0.2 -0.694 79.6-127.5 -87.9 142.3 98.5 1.8 46.0 136 159 A a G > S+ 0 0 34 86,-0.4 3,-1.6 -2,-0.3 -1,-0.1 0.817 106.4 61.8 -56.7 -33.3 96.5 4.0 43.5 137 160 A F G 3 S+ 0 0 98 1,-0.3 -1,-0.3 148,-0.1 148,-0.1 0.716 114.3 36.9 -65.8 -18.5 93.2 2.1 44.1 138 161 A S G < S+ 0 0 2 -3,-1.8 -1,-0.3 -6,-0.4 -2,-0.2 0.025 83.1 149.6-117.8 25.1 93.4 3.2 47.7 139 162 A A < - 0 0 6 -3,-1.6 87,-0.1 1,-0.1 -5,-0.1 -0.377 62.6 -94.8 -62.6 133.0 94.9 6.7 47.2 140 163 A P - 0 0 6 0, 0.0 2,-2.0 0, 0.0 -16,-0.2 -0.273 31.3-136.3 -51.5 120.8 93.6 9.0 50.0 141 164 A P + 0 0 1 0, 0.0 4,-0.1 0, 0.0 8,-0.0 -0.495 42.9 172.0 -81.3 69.6 90.6 10.8 48.6 142 165 A A - 0 0 2 -2,-2.0 -59,-0.1 2,-0.3 3,-0.1 -0.091 50.8-106.9 -74.8 169.3 91.6 14.2 49.9 143 166 A A S S+ 0 0 2 1,-0.2 -59,-2.1 -27,-0.1 2,-0.8 0.842 113.9 61.3 -59.3 -36.5 90.1 17.6 49.3 144 167 A A S S+ 0 0 1 -62,-0.2 2,-0.4 -60,-0.1 -2,-0.3 -0.849 70.2 160.0-100.7 107.8 93.2 18.3 47.2 145 168 A I + 0 0 1 -2,-0.8 2,-0.4 -60,-0.2 -62,-0.1 -0.988 12.5 175.2-127.4 131.8 93.3 15.8 44.3 146 169 A V S > S- 0 0 0 -2,-0.4 3,-2.0 1,-0.1 4,-0.4 -0.984 76.8 -12.0-137.0 124.1 95.3 16.3 41.0 147 170 A D G > S- 0 0 53 -59,-2.7 3,-1.5 -2,-0.4 -58,-0.1 0.941 126.6 -59.6 46.1 49.5 95.4 13.5 38.4 148 171 A R G 3 S- 0 0 99 -60,-0.5 -1,-0.3 -62,-0.3 3,-0.1 0.498 79.5 -87.3 65.9 10.0 93.9 11.1 40.9 149 172 A N G < S+ 0 0 1 -3,-2.0 76,-2.8 1,-0.2 2,-0.4 0.867 97.8 119.4 59.3 40.2 96.8 11.6 43.4 150 173 A a E < +N 224 0E 33 -3,-1.5 2,-0.3 -4,-0.4 -1,-0.2 -0.983 35.8 173.7-138.3 138.6 98.7 8.8 41.6 151 174 A F E -N 223 0E 2 72,-2.1 72,-2.2 -2,-0.4 2,-0.3 -0.906 19.7-131.2-139.3 168.8 102.1 9.0 39.9 152 175 A S E -N 222 0E 59 -2,-0.3 18,-0.5 70,-0.2 2,-0.3 -0.895 16.1-173.9-133.6 161.5 104.4 6.5 38.4 153 176 A V E -NO 221 169E 4 68,-2.7 68,-2.5 -2,-0.3 2,-0.5 -0.901 19.9-130.9-146.9 155.2 108.1 5.7 38.6 154 177 A S E -NO 220 168E 37 14,-2.8 14,-2.7 -2,-0.3 2,-0.6 -0.990 15.9-156.0-118.4 128.0 110.6 3.4 36.9 155 178 A L E -NO 219 167E 0 64,-3.1 64,-4.0 -2,-0.5 2,-0.4 -0.926 10.7-166.6-106.7 123.9 112.9 1.2 38.9 156 179 A Y E - O 0 166E 59 10,-2.9 10,-2.4 -2,-0.6 2,-0.1 -0.906 17.9-129.0-109.2 131.6 116.1 0.1 37.2 157 180 A S - 0 0 16 -2,-0.4 7,-0.1 58,-0.3 8,-0.1 -0.432 34.1-106.6 -70.8 150.6 118.4 -2.6 38.5 158 181 A A - 0 0 5 5,-0.4 7,-0.1 2,-0.1 5,-0.1 -0.559 19.2-124.1 -75.1 142.4 122.0 -1.7 38.7 159 182 A P S S+ 0 0 115 0, 0.0 -1,-0.1 0, 0.0 -2,-0.0 0.891 101.3 51.7 -50.6 -44.8 124.5 -3.2 36.1 160 183 A K S > S- 0 0 154 4,-0.1 3,-1.9 25,-0.0 23,-0.2 -0.879 95.1-118.5 -99.9 122.8 126.6 -4.6 38.9 161 184 A P T 3 S+ 0 0 57 0, 0.0 23,-0.2 0, 0.0 3,-0.1 -0.234 100.6 35.4 -51.3 140.7 125.0 -6.7 41.6 162 185 A G T 3 S+ 0 0 46 21,-2.8 2,-0.2 1,-0.4 22,-0.1 0.069 94.7 115.9 93.4 -22.9 125.2 -5.2 45.1 163 186 A D S < S- 0 0 93 -3,-1.9 20,-1.7 1,-0.1 -1,-0.4 -0.513 79.7 -90.1 -77.7 153.1 124.9 -1.7 43.6 164 187 A M B -P 182 0F 107 18,-0.2 18,-0.2 -2,-0.2 -1,-0.1 -0.399 36.7-126.7 -67.3 122.3 121.9 0.5 44.4 165 188 A A - 0 0 0 16,-2.8 16,-0.4 -2,-0.2 2,-0.3 -0.420 33.9-135.4 -63.4 146.1 118.9 0.0 42.1 166 189 A F E -O 156 0E 67 -10,-2.4 -10,-2.9 -2,-0.1 2,-0.5 -0.859 8.3-137.1-124.0 152.4 117.9 3.5 40.7 167 190 A I E -O 155 0E 31 -2,-0.3 2,-0.5 -12,-0.2 -12,-0.2 -0.850 8.2-166.7-112.7 127.1 114.7 5.4 40.2 168 191 A R E +O 154 0E 148 -14,-2.7 -14,-2.8 -2,-0.5 2,-0.3 -0.913 14.9 171.8-108.9 135.6 113.5 7.5 37.3 169 192 A V E -O 153 0E 53 -2,-0.5 -16,-0.1 -16,-0.2 8,-0.0 -0.999 38.3 -97.3-140.5 140.2 110.5 9.8 37.7 170 193 A A > - 0 0 32 -18,-0.5 3,-1.8 -2,-0.3 -18,-0.0 -0.265 29.7-124.5 -58.6 140.7 109.0 12.4 35.5 171 194 A S T 3 S+ 0 0 124 1,-0.3 -1,-0.1 3,-0.1 0, 0.0 0.737 105.4 67.0 -54.2 -29.2 109.9 16.0 36.3 172 195 A Y T 3 S+ 0 0 109 2,-0.1 -1,-0.3 1,-0.0 -2,-0.1 0.354 80.1 87.9 -86.4 6.7 106.3 17.0 36.6 173 196 A Y < - 0 0 46 -3,-1.8 2,-2.2 2,-0.1 -22,-0.0 -0.942 69.9-148.0-104.5 113.9 105.6 15.0 39.7 174 197 A P + 0 0 42 0, 0.0 2,-0.3 0, 0.0 60,-0.1 -0.505 58.4 114.7 -78.5 72.4 106.4 16.9 42.9 175 198 A V - 0 0 18 -2,-2.2 2,-0.5 50,-0.0 30,-0.2 -0.871 61.5-130.6-130.4 165.1 107.5 13.9 44.9 176 199 A T E - q 0 205F 62 28,-2.3 30,-3.1 -2,-0.3 2,-0.4 -0.976 23.1-163.6-123.4 114.7 110.9 12.9 46.3 177 200 A M E - q 0 206F 31 -2,-0.5 2,-0.4 28,-0.2 30,-0.2 -0.820 8.4-178.2-101.4 136.1 112.2 9.4 45.6 178 201 A F E - q 0 207F 108 28,-2.6 30,-3.0 -2,-0.4 2,-0.5 -0.993 13.4-148.3-126.7 141.8 115.0 7.6 47.4 179 202 A S E + q 0 208F 16 -2,-0.4 30,-0.2 28,-0.2 -15,-0.1 -0.934 30.3 158.9-113.4 127.0 116.4 4.2 46.7 180 203 A Q E + q 0 209F 136 28,-3.2 30,-0.8 -2,-0.5 2,-0.5 -0.103 40.8 134.4-121.4 30.8 117.8 1.8 49.3 181 204 A V E - q 0 210F 2 -16,-0.4 -16,-2.8 28,-0.2 2,-0.5 -0.703 47.8-145.9 -91.3 123.5 117.2 -1.2 47.0 182 205 A R E -Pq 164 211F 102 28,-3.1 30,-2.2 -2,-0.5 2,-0.4 -0.779 15.3-130.8 -92.8 129.2 120.1 -3.7 46.6 183 206 A T E - q 0 212F 1 -20,-1.7 -21,-2.8 -2,-0.5 -20,-0.1 -0.700 24.9-143.8 -79.7 128.1 120.4 -5.2 43.2 184 207 A L E - q 0 213F 2 28,-2.9 30,-2.2 -2,-0.4 3,-0.1 -0.772 12.9-116.1 -99.6 140.3 120.7 -9.0 43.5 185 208 A P > - 0 0 63 0, 0.0 3,-1.9 0, 0.0 -1,-0.0 -0.368 50.6 -89.1 -60.4 142.0 122.8 -11.3 41.3 186 209 A R T 3 S+ 0 0 168 1,-0.2 29,-0.0 27,-0.1 0, 0.0 -0.306 116.8 23.5 -52.3 138.0 120.6 -13.7 39.4 187 210 A G T 3 S+ 0 0 86 1,-0.2 -1,-0.2 -3,-0.1 0, 0.0 0.502 84.8 163.5 78.8 7.2 120.0 -16.8 41.5 188 211 A S X - 0 0 30 -3,-1.9 3,-1.3 1,-0.1 4,-0.3 -0.244 45.1-133.9 -56.4 140.1 120.7 -15.1 44.9 189 212 A A G > S+ 0 0 99 1,-0.2 3,-0.8 2,-0.1 4,-0.4 0.774 103.8 67.2 -63.0 -26.5 119.5 -17.0 47.9 190 213 A E G 3> S+ 0 0 77 1,-0.2 4,-1.6 2,-0.1 -1,-0.2 0.652 78.2 79.5 -65.5 -19.0 118.1 -13.7 49.1 191 214 A A G <4 S+ 0 0 47 -3,-1.3 -1,-0.2 1,-0.2 -2,-0.1 0.788 82.8 61.6 -72.9 -22.0 115.5 -13.4 46.4 192 215 A Q T <4 S+ 0 0 156 -3,-0.8 -1,-0.2 -4,-0.3 -2,-0.1 0.956 122.0 15.7 -67.7 -48.9 112.9 -15.7 48.0 193 216 A Y T 4 S+ 0 0 185 -4,-0.4 2,-0.7 -3,-0.2 -2,-0.2 0.399 96.6 103.4-111.8 4.1 112.3 -13.7 51.2 194 217 A b < - 0 0 38 -4,-1.6 2,-0.1 16,-0.0 17,-0.0 -0.789 62.7-148.6 -88.1 117.0 113.7 -10.3 50.5 195 218 A E - 0 0 122 -2,-0.7 16,-1.6 15,-0.1 2,-0.6 -0.418 11.6-133.8 -82.3 156.1 110.8 -8.0 49.8 196 219 A L E -R 210 0F 55 14,-0.2 2,-0.3 -2,-0.1 14,-0.2 -0.977 42.5-178.8-102.8 116.0 110.7 -4.9 47.5 197 220 A D E -R 209 0F 79 12,-2.5 12,-2.5 -2,-0.6 2,-0.4 -0.875 30.3-144.3-125.9 154.0 109.0 -2.3 49.6 198 221 A V E -R 208 0F 31 -2,-0.3 10,-0.2 10,-0.2 -64,-0.1 -0.950 14.4-170.1-111.4 132.2 107.8 1.3 49.5 199 222 A V E -R 207 0F 75 8,-2.6 8,-2.4 -2,-0.4 2,-0.1 -0.917 12.1-149.5-125.4 104.5 108.0 3.4 52.6 200 223 A P E -R 206 0F 42 0, 0.0 6,-0.2 0, 0.0 2,-0.2 -0.434 17.4-176.5 -71.8 142.9 106.3 6.8 52.5 201 224 A G E >> -R 205 0F 37 4,-3.0 4,-0.6 1,-0.2 3,-0.5 -0.661 37.9 -58.2-122.6-175.2 107.7 9.7 54.5 202 225 A D G >4 S+ 0 0 128 -2,-0.2 3,-0.6 1,-0.2 -1,-0.2 -0.277 113.3 21.6 -63.5 151.1 106.6 13.3 55.1 203 226 A L G 34 S- 0 0 98 1,-0.2 -1,-0.2 -3,-0.1 -27,-0.1 0.881 134.2 -57.5 63.5 40.8 106.0 15.8 52.2 204 227 A N G <4 S+ 0 0 4 -3,-0.5 -28,-2.3 1,-0.2 2,-0.4 0.831 91.7 153.4 58.3 37.2 105.5 13.2 49.5 205 228 A R E << -qR 176 201F 111 -3,-0.6 -4,-3.0 -4,-0.6 2,-0.4 -0.767 22.2-169.7 -86.8 139.7 108.9 11.5 50.1 206 229 A F E -qR 177 200F 0 -30,-3.1 -28,-2.6 -2,-0.4 2,-0.5 -0.996 7.5-163.4-131.9 135.3 109.1 7.9 49.2 207 230 A T E -qR 178 199F 29 -8,-2.4 -8,-2.6 -2,-0.4 2,-0.4 -0.961 8.7-151.1-117.1 128.5 111.9 5.4 50.0 208 231 A L E +qR 179 198F 1 -30,-3.0 -28,-3.2 -2,-0.5 2,-0.3 -0.820 25.1 177.7 -93.1 131.9 112.2 2.1 48.1 209 232 A T E +qR 180 197F 30 -12,-2.5 -12,-2.5 -2,-0.4 2,-0.4 -0.896 30.5 31.6-133.0 165.7 113.9 -0.6 50.2 210 233 A G E S-qR 181 196F 24 -30,-0.8 -28,-3.1 -2,-0.3 2,-0.4 -0.750 87.9 -26.1 98.4-138.2 114.9 -4.3 50.0 211 234 A b E -q 182 0F 6 -16,-1.6 -28,-0.2 -2,-0.4 -2,-0.1 -0.927 33.8-173.1-130.0 146.9 115.9 -6.2 47.0 212 235 A L E -q 183 0F 6 -30,-2.2 -28,-2.9 -2,-0.4 3,-0.1 -0.988 26.3-131.5-133.0 121.4 115.5 -6.3 43.2 213 236 A P E -q 184 0F 63 0, 0.0 -56,-0.1 0, 0.0 -27,-0.1 -0.419 44.7 -87.3 -63.0 144.8 116.9 -9.2 41.1 214 237 A Q + 0 0 48 -30,-2.2 2,-0.3 -57,-0.1 -58,-0.0 -0.308 58.6 179.0 -49.3 133.3 118.8 -8.0 38.1 215 238 A R - 0 0 98 -3,-0.1 -58,-0.3 -57,-0.1 4,-0.1 -0.977 35.1-133.9-145.0 153.4 116.4 -7.4 35.2 216 239 A S S S+ 0 0 107 -2,-0.3 -1,-0.1 2,-0.1 -2,-0.0 0.795 90.6 41.5 -81.0 -34.9 116.8 -6.3 31.6 217 240 A E S S- 0 0 132 1,-0.1 -60,-0.2 -61,-0.0 -62,-0.0 -0.820 96.1 -95.8-109.6 154.0 113.9 -3.7 31.6 218 241 A P - 0 0 29 0, 0.0 -62,-0.3 0, 0.0 -1,-0.1 -0.254 36.1-117.0 -59.0 152.6 112.9 -1.2 34.4 219 242 A L E -N 155 0E 39 -64,-4.0 -64,-3.1 -4,-0.1 2,-0.4 -0.867 27.7-140.4 -90.3 119.4 110.2 -2.2 36.8 220 243 A P E -N 154 0E 99 0, 0.0 2,-0.4 0, 0.0 -66,-0.2 -0.675 25.2-180.0 -82.1 133.7 107.2 0.2 36.4 221 244 A L E -N 153 0E 42 -68,-2.5 -68,-2.7 -2,-0.4 2,-0.4 -0.979 16.1-159.1-135.2 141.8 105.5 1.2 39.7 222 245 A A E -N 152 0E 47 -2,-0.4 -86,-0.4 -70,-0.2 2,-0.3 -0.989 15.6-174.3-122.9 133.3 102.6 3.4 40.4 223 246 A F E -N 151 0E 11 -72,-2.2 -72,-2.1 -2,-0.4 2,-0.4 -0.895 24.2-116.1-126.3 154.1 102.1 5.0 43.9 224 247 A A E -N 150 0E 0 -90,-2.4 -74,-0.3 -2,-0.3 2,-0.2 -0.758 31.4-117.4 -86.4 137.4 99.5 7.1 45.7 225 248 A V - 0 0 1 -76,-2.8 3,-0.2 -2,-0.4 -50,-0.0 -0.538 22.8-162.3 -67.6 128.5 100.3 10.6 46.9 226 249 A Q S S+ 0 0 37 -2,-0.2 2,-0.5 1,-0.2 -1,-0.1 0.674 80.3 46.0 -86.1 -25.1 100.0 10.6 50.7 227 250 A D > + 0 0 42 1,-0.2 4,-2.2 2,-0.1 -1,-0.2 -0.772 63.1 176.7-125.7 82.9 99.8 14.4 51.2 228 251 A G H > S+ 0 0 3 -2,-0.5 4,-2.9 -3,-0.2 5,-0.3 0.852 78.3 54.2 -55.2 -42.4 97.4 15.8 48.6 229 252 A A H > S+ 0 0 7 2,-0.2 4,-2.6 1,-0.2 -1,-0.2 0.934 111.1 44.5 -58.2 -46.7 97.6 19.4 49.9 230 253 A S H > S+ 0 0 42 2,-0.2 4,-2.3 1,-0.2 -1,-0.2 0.885 115.0 49.3 -65.7 -41.7 101.4 19.5 49.6 231 254 A Y H X S+ 0 0 2 -4,-2.2 4,-2.3 2,-0.2 -2,-0.2 0.959 113.8 44.2 -62.7 -52.0 101.3 17.9 46.2 232 255 A A H X S+ 0 0 0 -4,-2.9 4,-2.8 2,-0.2 -2,-0.2 0.882 113.3 53.4 -60.2 -42.7 98.6 20.3 44.9 233 256 A G H X S+ 0 0 4 -4,-2.6 4,-2.7 -5,-0.3 -1,-0.2 0.940 107.6 49.6 -55.2 -47.5 100.5 23.2 46.4 234 257 A A H X S+ 0 0 38 -4,-2.3 4,-2.6 1,-0.2 -2,-0.2 0.921 111.8 48.5 -64.0 -41.0 103.7 22.3 44.7 235 258 A I H X S+ 0 0 8 -4,-2.3 4,-2.8 1,-0.2 -1,-0.2 0.945 112.4 48.3 -65.5 -42.6 101.9 22.0 41.4 236 259 A L H X S+ 0 0 2 -4,-2.8 4,-3.1 2,-0.2 -2,-0.2 0.914 110.8 51.5 -61.9 -40.7 100.2 25.4 41.9 237 260 A K H X S+ 0 0 94 -4,-2.7 4,-2.2 2,-0.2 -1,-0.2 0.923 109.9 49.3 -63.4 -44.2 103.5 26.9 42.8 238 261 A Y H X S+ 0 0 117 -4,-2.6 4,-2.3 -5,-0.2 -2,-0.2 0.956 113.1 46.7 -56.7 -51.3 105.1 25.5 39.7 239 262 A E H X S+ 0 0 19 -4,-2.8 4,-2.0 1,-0.2 6,-0.2 0.905 109.7 53.5 -63.7 -40.3 102.2 26.9 37.5 240 263 A L H <>S+ 0 0 0 -4,-3.1 5,-2.3 1,-0.2 -1,-0.2 0.945 111.1 46.7 -54.7 -48.5 102.4 30.3 39.2 241 264 A K H ><5S+ 0 0 118 -4,-2.2 3,-1.8 1,-0.2 -2,-0.2 0.904 109.7 53.1 -63.3 -43.4 106.1 30.6 38.4 242 265 A Q H 3<5S+ 0 0 124 -4,-2.3 -1,-0.2 1,-0.3 -2,-0.2 0.844 107.4 51.3 -62.3 -34.8 105.7 29.5 34.8 243 266 A A T 3<5S- 0 0 35 -4,-2.0 -1,-0.3 -5,-0.2 -2,-0.2 0.365 120.5-112.1 -83.5 6.7 103.0 32.1 34.3 244 267 A G T < 5 + 0 0 46 -3,-1.8 2,-0.4 1,-0.3 -3,-0.2 0.574 68.5 144.8 75.9 12.0 105.5 34.7 35.7 245 268 A I < - 0 0 2 -5,-2.3 2,-0.3 -6,-0.2 -1,-0.3 -0.707 28.6-167.8 -84.0 127.7 103.5 35.4 38.9 246 269 A T E -k 107 0C 79 -140,-1.5 -138,-3.0 -2,-0.4 2,-0.3 -0.776 6.4-167.7-109.2 161.0 105.6 36.0 42.0 247 270 A W E -k 108 0C 38 -2,-0.3 -138,-0.2 -140,-0.2 -136,-0.1 -0.992 19.7-146.3-145.8 150.3 104.6 36.2 45.7 248 271 A S S S+ 0 0 79 -140,-2.0 -137,-0.1 -2,-0.3 -139,-0.1 0.664 80.4 53.8 -89.3 -16.1 106.5 37.4 48.8 249 272 A G S S- 0 0 26 -139,-2.0 2,-0.3 -141,-0.3 -138,-0.2 0.319 85.8 -93.8 -97.8-141.9 105.1 34.9 51.3 250 273 A T - 0 0 80 -138,-0.0 -138,-2.2 0, 0.0 2,-0.7 -0.874 35.2 -88.5-134.9 174.2 104.9 31.2 51.5 251 274 A L E +l 112 0C 53 -2,-0.3 2,-0.4 -140,-0.2 -138,-0.2 -0.751 52.4 177.4 -81.4 114.5 102.7 28.3 50.6 252 275 A L E -l 113 0C 76 -140,-2.4 -138,-3.1 -2,-0.7 2,-0.3 -0.944 28.4-123.0-121.6 147.7 100.4 27.6 53.6 253 276 A R E -l 114 0C 122 -2,-0.4 2,-0.5 -140,-0.2 -138,-0.2 -0.654 18.4-157.1 -82.3 142.4 97.6 25.2 54.3 254 277 A Q E +l 115 0C 40 -140,-2.9 -138,-2.5 -2,-0.3 -137,-0.6 -0.977 24.1 160.0-119.1 114.8 94.3 26.6 55.3 255 278 A T + 0 0 64 -2,-0.5 2,-0.3 -140,-0.2 -1,-0.1 0.556 45.1 92.5-110.0 -14.6 92.1 24.1 57.2 256 279 A Q S S- 0 0 140 1,-0.1 -139,-0.2 -136,-0.0 -138,-0.1 -0.638 84.8-102.5 -89.6 138.5 89.6 26.4 59.0 257 280 A V + 0 0 104 -2,-0.3 2,-0.3 -140,-0.1 -1,-0.1 -0.268 53.2 166.7 -55.9 144.6 86.3 27.3 57.5 258 281 A N - 0 0 36 -3,-0.0 3,-0.1 3,-0.0 -1,-0.0 -0.975 41.2 -86.3-157.4 157.8 86.4 30.9 56.1 259 282 A E - 0 0 160 -2,-0.3 0, 0.0 1,-0.1 0, 0.0 -0.516 53.9-105.5 -72.0 135.7 84.4 33.2 53.9 260 283 A P - 0 0 78 0, 0.0 -1,-0.1 0, 0.0 3,-0.1 -0.312 29.5-137.6 -60.4 146.2 85.2 32.9 50.2 261 284 A G - 0 0 18 1,-0.1 2,-0.6 -182,-0.1 -195,-0.2 -0.044 50.1 -57.4 -78.8-166.2 87.3 35.6 48.5 262 285 A T E -G 65 0C 98 -197,-2.4 -197,-1.8 -195,-0.1 2,-0.7 -0.710 58.8-125.8 -76.7 121.1 86.5 37.0 45.1 263 286 A V E +G 64 0C 77 -2,-0.6 -199,-0.3 -199,-0.2 3,-0.1 -0.579 38.1 167.2 -76.0 113.2 86.5 34.0 42.7 264 287 A V E + 0 0 34 -201,-2.7 2,-0.3 -2,-0.7 -200,-0.2 0.723 67.5 11.2 -97.6 -29.0 88.9 34.8 39.8 265 288 A A E +G 63 0C 7 -202,-1.6 -202,-2.3 2,-0.0 2,-0.3 -0.983 67.6 178.8-146.6 158.8 89.0 31.4 38.3 266 289 A S E -G 62 0C 75 -2,-0.3 2,-0.3 -204,-0.2 -204,-0.2 -0.990 16.2-161.6-158.3 154.3 87.1 28.1 38.6 267 290 A K E -G 61 0C 65 -206,-2.1 -206,-2.7 -2,-0.3 2,-0.4 -0.977 11.5-165.3-140.6 132.4 86.7 24.5 37.4 268 291 A Q E -G 60 0C 98 -2,-0.3 -208,-0.2 -208,-0.2 2,-0.1 -0.916 18.9-126.0-117.7 142.5 83.6 22.4 37.9 269 292 A S - 0 0 1 -210,-1.8 3,-0.1 -2,-0.4 -184,-0.0 -0.302 43.5 -77.7 -73.4 166.8 83.5 18.6 37.4 270 293 A A S S- 0 0 40 1,-0.1 -211,-0.4 -212,-0.1 -1,-0.2 -0.224 71.9 -76.4 -48.4 154.4 81.1 16.8 35.1 271 294 A P >> - 0 0 16 0, 0.0 4,-1.7 0, 0.0 3,-0.8 -0.245 44.2-108.7 -61.6 153.7 77.6 16.6 36.8 272 295 A L H 3> S+ 0 0 0 -215,-2.5 4,-3.5 1,-0.3 5,-0.3 0.844 116.6 60.9 -54.8 -39.0 77.2 14.0 39.5 273 296 A H H 3> S+ 0 0 77 -218,-2.7 4,-1.7 1,-0.2 -1,-0.3 0.941 107.5 46.8 -57.3 -40.3 74.9 11.7 37.5 274 297 A D H <> S+ 0 0 72 -3,-0.8 4,-1.6 -219,-0.3 -1,-0.2 0.865 114.4 46.6 -64.5 -43.4 77.9 11.4 35.0 275 298 A L H X S+ 0 0 2 -4,-1.7 4,-2.8 2,-0.2 -1,-0.2 0.854 108.6 53.9 -68.7 -39.7 80.4 10.7 37.8 276 299 A L H X S+ 0 0 0 -4,-3.5 4,-2.4 2,-0.2 -2,-0.2 0.870 106.5 53.9 -65.6 -31.8 78.1 8.2 39.5 277 300 A K H X S+ 0 0 92 -4,-1.7 4,-2.7 -5,-0.3 5,-0.2 0.924 110.8 45.1 -63.6 -45.9 77.9 6.3 36.2 278 301 A I H X S+ 0 0 71 -4,-1.6 4,-2.5 1,-0.2 5,-0.4 0.957 113.2 52.7 -57.6 -48.6 81.7 6.1 35.9 279 302 A M H X>S+ 0 0 0 -4,-2.8 5,-1.2 1,-0.2 4,-1.2 0.876 115.4 38.5 -56.0 -43.3 81.8 5.1 39.6 280 303 A L H <5S+ 0 0 0 -4,-2.4 -1,-0.2 3,-0.2 -2,-0.2 0.840 118.1 48.0 -80.8 -36.8 79.3 2.2 39.1 281 304 A K H <5S+ 0 0 43 -4,-2.7 94,-0.7 -5,-0.2 -2,-0.2 0.794 128.9 23.7 -72.5 -30.0 80.6 1.0 35.7 282 305 A K H <5S- 0 0 150 -4,-2.5 -2,-0.2 -5,-0.2 3,-0.2 0.477 99.2-122.3-116.3 -5.7 84.3 1.0 36.9 283 306 A S T <5 - 0 0 27 -4,-1.2 2,-1.0 -5,-0.4 -3,-0.2 0.982 38.5-167.4 55.9 56.8 83.9 0.7 40.7 284 307 A D >< - 0 0 18 -5,-1.2 4,-2.0 -6,-0.2 -1,-0.2 -0.699 12.9-168.4 -82.5 104.4 85.9 4.0 41.0 285 308 A N H > S+ 0 0 24 -2,-1.0 4,-2.8 1,-0.2 5,-0.2 0.866 82.9 55.9 -60.8 -34.3 86.8 4.2 44.8 286 309 A M H > S+ 0 0 7 1,-0.2 4,-2.2 2,-0.2 5,-0.3 0.911 108.7 44.9 -74.5 -38.8 87.9 7.8 44.5 287 310 A I H > S+ 0 0 2 2,-0.2 4,-2.2 -3,-0.2 -1,-0.2 0.925 114.7 51.8 -65.3 -39.5 84.7 9.1 43.1 288 311 A A H X S+ 0 0 0 -4,-2.0 4,-2.0 1,-0.2 -2,-0.2 0.922 114.2 40.8 -62.0 -45.7 82.8 6.9 45.8 289 312 A D H X S+ 0 0 2 -4,-2.8 4,-2.0 2,-0.2 -1,-0.2 0.789 113.3 50.1 -82.0 -32.1 84.8 8.3 48.7 290 313 A T H X S+ 0 0 0 -4,-2.2 4,-2.0 -5,-0.2 -1,-0.2 0.932 114.4 48.3 -66.0 -44.3 85.0 12.0 47.7 291 314 A V H X S+ 0 0 0 -4,-2.2 4,-2.2 -5,-0.3 -2,-0.2 0.938 108.4 56.5 -56.8 -42.4 81.2 11.8 47.2 292 315 A F H X S+ 0 0 0 -4,-2.0 4,-1.3 1,-0.3 -1,-0.2 0.919 110.8 39.2 -63.8 -47.7 80.8 10.1 50.6 293 316 A R H X S+ 0 0 0 -4,-2.0 4,-2.2 1,-0.2 -1,-0.3 0.836 111.7 60.2 -72.8 -26.2 82.5 12.8 52.6 294 317 A M H X S+ 0 0 10 -4,-2.0 4,-3.1 2,-0.2 -2,-0.2 0.890 99.9 56.6 -61.8 -39.8 80.7 15.4 50.4 295 318 A I H X S+ 0 0 0 -4,-2.2 4,-2.7 2,-0.2 5,-0.2 0.918 108.3 46.4 -55.0 -47.1 77.3 14.0 51.5 296 319 A G H X S+ 0 0 0 -4,-1.3 4,-2.6 2,-0.2 5,-0.3 0.939 112.3 50.3 -64.8 -46.9 78.2 14.6 55.2 297 320 A H H X>S+ 0 0 53 -4,-2.2 4,-2.1 1,-0.2 5,-0.7 0.961 115.2 43.6 -52.0 -55.9 79.5 18.1 54.5 298 321 A A H <5S+ 0 0 30 -4,-3.1 -2,-0.2 1,-0.2 -1,-0.2 0.837 115.3 47.1 -58.3 -40.5 76.2 18.9 52.6 299 322 A R H <5S+ 0 0 50 -4,-2.7 -1,-0.2 -5,-0.2 -2,-0.2 0.895 127.2 23.8 -74.7 -36.6 73.8 17.3 55.1 300 323 A F H <5S- 0 0 64 -4,-2.6 -2,-0.2 -5,-0.2 -1,-0.2 0.489 94.1-127.4-110.8 -4.6 75.3 18.8 58.2 301 324 A N T <5S+ 0 0 139 -4,-2.1 -3,-0.2 -5,-0.3 -4,-0.1 0.950 71.1 114.3 54.6 54.1 77.1 21.9 57.0 302 325 A V S - 0 0 32 -186,-0.2 4,-2.5 -2,-0.2 -9,-0.2 -0.838 48.0-107.1-129.7 169.6 84.6 13.7 57.8 306 329 A W H > S+ 0 0 13 -2,-0.3 4,-2.4 -184,-0.2 5,-0.1 0.894 121.2 49.2 -63.4 -40.3 84.2 10.0 57.6 307 330 A R H > S+ 0 0 191 2,-0.2 4,-2.4 1,-0.2 5,-0.2 0.904 110.6 49.7 -67.2 -42.4 81.9 10.0 60.7 308 331 A A H > S+ 0 0 9 1,-0.2 4,-2.6 2,-0.2 -2,-0.2 0.919 110.8 51.2 -60.7 -44.2 79.8 12.8 59.2 309 332 A G H X S+ 0 0 0 -4,-2.5 4,-2.5 2,-0.2 5,-0.2 0.929 111.0 47.4 -56.4 -50.0 79.5 10.8 56.0 310 333 A S H X S+ 0 0 24 -4,-2.4 4,-2.2 1,-0.2 -2,-0.2 0.906 114.1 45.8 -61.0 -47.6 78.4 7.6 57.8 311 334 A D H X S+ 0 0 72 -4,-2.4 4,-2.4 2,-0.2 -1,-0.2 0.907 114.0 50.2 -59.4 -45.0 75.8 9.5 60.0 312 335 A A H X S+ 0 0 0 -4,-2.6 4,-2.8 -5,-0.2 5,-0.2 0.942 110.9 47.1 -64.2 -45.4 74.4 11.3 56.9 313 336 A V H X S+ 0 0 0 -4,-2.5 4,-2.7 1,-0.2 5,-0.3 0.944 112.8 50.1 -64.3 -45.1 74.0 8.2 54.7 314 337 A R H X S+ 0 0 88 -4,-2.2 4,-1.9 1,-0.2 11,-0.2 0.923 114.7 44.8 -54.9 -45.5 72.3 6.4 57.6 315 338 A Q H X S+ 0 0 64 -4,-2.4 4,-3.0 2,-0.2 5,-0.4 0.898 112.2 50.3 -67.4 -42.4 70.0 9.4 58.0 316 339 A I H X>S+ 0 0 0 -4,-2.8 4,-2.2 1,-0.2 5,-1.0 0.900 111.7 48.8 -64.6 -46.3 69.3 9.8 54.3 317 340 A L H X5S+ 0 0 0 -4,-2.7 6,-3.1 -5,-0.2 4,-0.5 0.889 117.4 41.5 -63.0 -39.1 68.4 6.1 53.9 318 341 A R H X5S+ 0 0 133 -4,-1.9 4,-0.6 -5,-0.3 -2,-0.2 0.954 124.3 32.2 -72.4 -47.7 66.1 6.2 57.0 319 342 A Q H <5S+ 0 0 118 -4,-3.0 -3,-0.2 -5,-0.2 -2,-0.2 0.874 132.1 27.0 -88.2 -38.5 64.3 9.5 56.4 320 343 A Q H <5S+ 0 0 80 -4,-2.2 -3,-0.2 -5,-0.4 -1,-0.1 0.731 132.6 31.8 -94.7 -27.3 64.2 9.8 52.6 321 344 A A H < - 0 0 4 -2,-0.8 3,-2.2 -11,-0.2 -1,-0.1 0.506 17.9-173.9 -80.8 -3.8 69.7 0.1 58.4 326 349 A G T 3 + 0 0 34 1,-0.3 -1,-0.2 -12,-0.1 -3,-0.0 -0.199 67.1 2.5 56.2-126.0 69.7 -0.9 62.0 327 350 A N T 3 S+ 0 0 140 2,-0.1 -1,-0.3 0, 0.0 -2,-0.1 0.317 96.7 129.4 -79.3 3.7 73.0 -2.5 63.1 328 351 A T < - 0 0 2 -3,-2.2 2,-0.5 1,-0.1 14,-0.2 -0.277 51.5-142.4 -51.5 145.8 74.6 -2.0 59.7 329 352 A I B -S 341 0G 83 12,-2.7 12,-2.5 10,-0.1 2,-0.5 -0.985 15.3-172.1-116.6 122.5 78.0 -0.3 59.8 330 353 A I + 0 0 11 -2,-0.5 -16,-0.1 10,-0.2 3,-0.1 -0.975 14.9 162.6-110.3 120.1 78.8 2.1 57.0 331 354 A A - 0 0 6 -2,-0.5 2,-0.3 1,-0.2 -21,-0.2 0.632 61.8 -6.5-113.3 -27.0 82.4 3.2 57.1 332 355 A D - 0 0 0 5,-0.1 -1,-0.2 -207,-0.1 -43,-0.1 -0.916 62.3-109.3-152.0-172.9 83.0 4.6 53.7 333 356 A G S S+ 0 0 0 -2,-0.3 -288,-0.3 -48,-0.1 -287,-0.1 0.748 107.8 48.3 -92.3 -31.4 81.6 5.2 50.2 334 357 A S S S- 0 0 0 -49,-0.1 -292,-0.4 -293,-0.1 -293,-0.2 0.681 101.5-119.6 -84.8 -22.1 83.7 2.8 48.1 335 358 A G S S+ 0 0 6 -294,-0.2 -297,-0.2 -295,-0.1 -296,-0.1 0.496 77.2 124.0 84.3 8.5 83.5 -0.4 50.3 336 359 A L + 0 0 21 -298,-0.1 -297,-0.1 -297,-0.1 2,-0.1 0.884 47.9 94.0 -60.8 -39.3 87.3 -0.4 50.8 337 360 A S > - 0 0 0 1,-0.2 3,-0.9 -209,-0.1 -299,-0.3 -0.337 67.7-149.5 -64.5 137.2 86.9 -0.4 54.5 338 361 A R T 3 S+ 0 0 113 -211,-2.5 -1,-0.2 1,-0.2 -211,-0.1 0.482 95.2 70.2 -79.5 -4.0 86.9 -3.8 56.3 339 362 A H T 3 S+ 0 0 104 -213,-0.4 -1,-0.2 -303,-0.0 -212,-0.1 0.661 70.6 108.6 -81.6 -17.5 84.5 -2.2 58.9 340 363 A N < + 0 0 2 -3,-0.9 2,-0.3 -213,-0.1 -10,-0.2 -0.433 46.6 173.7 -65.5 132.0 81.6 -2.0 56.4 341 364 A L B +S 329 0G 62 -12,-2.5 -12,-2.7 -305,-0.2 2,-0.3 -0.936 5.3 153.5-150.5 121.5 79.1 -4.6 57.5 342 365 A I B -F 35 0B 0 -307,-2.5 -307,-3.0 -2,-0.3 -309,-0.0 -0.993 33.2-129.2-154.1 141.2 75.6 -5.2 56.0 343 366 A A >> - 0 0 4 -2,-0.3 4,-2.3 -309,-0.3 3,-0.9 -0.728 27.8-119.0 -88.4 146.0 73.0 -8.0 55.6 344 367 A P H 3> S+ 0 0 0 0, 0.0 4,-2.8 0, 0.0 -312,-0.2 0.853 115.1 60.8 -46.6 -39.6 71.4 -9.0 52.2 345 368 A A H 3> S+ 0 0 19 -314,-3.0 4,-1.2 2,-0.2 -313,-0.1 0.848 106.7 44.4 -61.0 -40.0 68.1 -8.1 53.8 346 369 A T H X> S+ 0 0 18 -3,-0.9 4,-1.5 -315,-0.3 3,-0.6 0.951 114.2 47.0 -69.7 -49.7 69.2 -4.5 54.4 347 370 A M H 3X S+ 0 0 0 -4,-2.3 4,-2.8 1,-0.2 -2,-0.2 0.846 107.0 61.0 -61.0 -32.3 70.8 -4.1 50.9 348 371 A M H 3X S+ 0 0 3 -4,-2.8 4,-2.9 -5,-0.3 -1,-0.2 0.887 101.4 52.1 -58.9 -39.8 67.5 -5.6 49.5 349 372 A Q H < S+ 0 0 13 -4,-3.3 3,-1.5 1,-0.2 4,-0.3 0.945 112.5 50.6 -61.1 -45.8 63.7 -0.2 41.6 356 379 A Q H 3< S+ 0 0 146 -4,-2.7 -1,-0.2 1,-0.3 3,-0.2 0.798 121.5 33.6 -58.3 -32.2 60.5 1.4 42.9 357 380 A H T >X S+ 0 0 39 -4,-2.0 4,-2.3 -3,-0.3 3,-1.3 0.130 82.7 115.5-110.1 20.1 61.9 4.9 42.2 358 381 A D H <> + 0 0 20 -3,-1.5 4,-2.5 1,-0.3 5,-0.3 0.837 68.9 60.6 -69.4 -29.0 63.9 4.1 39.1 359 382 A N H 34 S+ 0 0 172 -4,-0.3 -1,-0.3 -3,-0.2 -2,-0.1 0.811 114.4 40.2 -62.6 -24.8 61.9 6.2 36.7 360 383 A E H <4 S+ 0 0 146 -3,-1.3 -2,-0.2 1,-0.1 -1,-0.2 0.853 122.1 36.9 -85.1 -42.6 63.0 9.1 39.0 361 384 A L H < S- 0 0 33 -4,-2.3 -2,-0.2 -7,-0.2 -3,-0.2 0.768 83.9-145.3 -84.1 -26.6 66.6 8.2 39.8 362 385 A N < + 0 0 102 -4,-2.5 -3,-0.1 -5,-0.3 -4,-0.1 0.967 54.2 140.1 48.8 57.9 67.6 6.8 36.4 363 386 A F > + 0 0 0 -5,-0.3 3,-2.2 -9,-0.2 4,-0.4 0.902 47.6 58.7 -95.9 -51.0 69.7 4.5 38.5 364 387 A I G > S+ 0 0 6 1,-0.3 3,-1.4 2,-0.2 43,-0.1 0.813 98.5 61.2 -60.3 -34.5 69.5 1.0 37.0 365 388 A S G 3 S+ 0 0 51 1,-0.3 -1,-0.3 27,-0.1 -2,-0.1 0.739 98.6 60.0 -63.4 -20.4 70.9 2.1 33.6 366 389 A M G < S+ 0 0 9 -3,-2.2 -1,-0.3 -4,-0.1 -2,-0.2 0.643 87.3 90.7 -80.2 -20.7 74.1 3.2 35.5 367 390 A L S < S- 0 0 1 -3,-1.4 -86,-0.1 -4,-0.4 27,-0.1 -0.516 96.9 -85.7 -76.4 151.1 74.9 -0.4 36.8 368 391 A P - 0 0 0 0, 0.0 25,-1.9 0, 0.0 2,-0.5 -0.286 43.0-140.0 -52.2 131.5 77.0 -2.7 34.8 369 392 A L B > -C 392 0A 50 4,-0.4 3,-2.2 23,-0.2 23,-0.2 -0.898 25.0-110.2-101.0 123.8 74.8 -4.6 32.2 370 393 A A T 3 S+ 0 0 0 21,-3.0 19,-2.6 -2,-0.5 7,-0.2 -0.243 101.2 15.6 -56.6 131.0 75.8 -8.2 31.9 371 394 A G T 3 S+ 0 0 28 5,-3.1 2,-0.3 1,-0.3 -1,-0.3 0.460 111.8 93.7 85.9 0.4 77.4 -9.0 28.5 372 395 A Y S < S- 0 0 135 -3,-2.2 -1,-0.3 4,-0.1 4,-0.3 -0.831 94.4 -62.8-122.8 161.0 78.0 -5.3 27.7 373 396 A D S S+ 0 0 135 -2,-0.3 -4,-0.4 4,-0.1 2,-0.3 -0.161 100.1 59.0 -41.7 122.9 81.0 -3.0 28.3 374 397 A G S > S- 0 0 27 -6,-0.1 3,-1.7 1,-0.1 4,-0.2 -0.889 108.7 -41.0 144.9-168.7 81.6 -2.8 32.1 375 398 A S T 3 S+ 0 0 51 -94,-0.7 3,-0.2 1,-0.3 -2,-0.1 0.662 136.2 45.1 -64.4 -14.9 82.4 -5.0 35.1 376 399 A L T > S+ 0 0 1 -4,-0.3 -5,-3.1 -7,-0.2 3,-0.5 0.117 70.8 121.1-117.0 20.6 79.9 -7.7 33.8 377 400 A Q T < S+ 0 0 99 -3,-1.7 2,-0.3 1,-0.3 -1,-0.1 0.909 95.9 4.0 -47.2 -46.3 81.1 -7.7 30.2 378 401 A Y T 3 + 0 0 153 -4,-0.2 2,-0.6 -3,-0.2 -1,-0.3 -0.785 69.5 160.9-145.4 102.3 81.8 -11.4 30.7 379 402 A R X> - 0 0 10 -3,-0.5 4,-2.8 -2,-0.3 3,-0.6 -0.981 33.5-145.3-119.1 113.2 81.0 -13.1 33.9 380 403 A A H 3> S+ 0 0 12 -2,-0.6 4,-3.0 1,-0.3 5,-0.2 0.808 94.2 53.6 -55.0 -40.5 81.0 -16.7 33.0 381 404 A G H 3> S+ 0 0 0 2,-0.2 4,-1.7 1,-0.2 -1,-0.3 0.926 114.5 41.5 -57.4 -46.9 78.2 -17.7 35.4 382 405 A L H <4>S+ 0 0 0 -3,-0.6 5,-2.1 2,-0.2 4,-0.5 0.916 115.0 50.5 -71.4 -43.6 75.9 -15.1 34.0 383 406 A H H ><5S+ 0 0 95 -4,-2.8 3,-1.6 1,-0.2 5,-0.3 0.953 114.2 44.1 -57.9 -50.2 76.9 -15.7 30.4 384 407 A Q H 3<5S+ 0 0 74 -4,-3.0 -1,-0.2 1,-0.3 -2,-0.2 0.787 106.2 61.2 -67.8 -26.3 76.3 -19.5 30.8 385 408 A A T 3<5S- 0 0 2 -4,-1.7 -1,-0.3 -5,-0.2 -2,-0.2 0.592 113.8-120.1 -73.1 -11.0 73.1 -18.9 32.7 386 409 A G T < 5S+ 0 0 44 -3,-1.6 -3,-0.2 -4,-0.5 -2,-0.1 0.698 78.4 121.2 81.0 22.0 71.8 -17.2 29.5 387 410 A V >>< + 0 0 0 -5,-2.1 3,-2.5 -6,-0.1 4,-0.8 0.204 21.8 135.5-108.4 16.2 71.2 -13.9 31.3 388 411 A D T 34 S+ 0 0 47 -6,-0.3 -17,-0.2 -5,-0.3 -11,-0.1 -0.423 82.6 20.3 -57.6 139.0 73.5 -11.4 29.3 389 412 A G T 34 S+ 0 0 31 -19,-2.6 -1,-0.3 2,-0.3 -18,-0.1 0.284 115.9 76.1 82.6 -7.5 71.3 -8.4 28.8 390 413 A K T <4 S+ 0 0 73 -3,-2.5 19,-2.6 1,-0.1 2,-0.5 0.585 81.5 66.7-110.2 -14.6 69.1 -9.4 31.6 391 414 A V E < - D 0 408A 0 -4,-0.8 -21,-3.0 17,-0.2 2,-0.5 -0.962 48.1-178.0-118.2 129.2 71.1 -8.5 34.7 392 415 A S E +CD 369 407A 21 15,-2.4 15,-3.4 -2,-0.5 2,-0.3 -0.995 33.4 146.9-117.8 113.0 72.1 -5.0 35.9 393 416 A A E - D 0 406A 0 -25,-1.9 2,-0.4 -2,-0.5 13,-0.3 -1.000 47.6-124.0-155.1 151.2 74.3 -5.4 39.0 394 417 A K E - D 0 405A 0 11,-3.9 11,-2.3 -2,-0.3 2,-0.2 -0.834 28.7-144.7 -96.2 132.0 77.1 -4.1 41.1 395 418 A T E - D 0 404A 17 -2,-0.4 2,-0.3 9,-0.2 9,-0.2 -0.518 10.5-165.5 -86.9 159.1 80.0 -6.5 41.9 396 419 A G E + D 0 403A 0 7,-1.7 7,-2.9 -357,-0.2 2,-0.4 -0.832 23.6 175.7-142.5 103.4 82.0 -6.5 45.1 397 420 A S E + D 0 402A 67 -2,-0.3 2,-0.3 5,-0.2 5,-0.2 -0.929 14.1 144.6-123.0 138.1 85.2 -8.5 44.5 398 421 A L E > - D 0 401A 53 3,-1.5 3,-2.5 -2,-0.4 2,-0.2 -0.906 67.5 -61.0-152.6 167.3 88.2 -9.3 46.7 399 422 A Q T 3 S+ 0 0 189 -2,-0.3 25,-0.2 1,-0.3 27,-0.1 -0.447 132.1 5.1 -54.8 122.5 90.4 -12.4 47.1 400 423 A G T 3 S+ 0 0 7 25,-0.5 25,-2.3 -2,-0.2 2,-0.4 0.549 112.6 104.9 80.0 5.6 87.8 -14.9 48.2 401 424 A V E < +D 398 0A 13 -3,-2.5 -3,-1.5 22,-0.2 22,-0.2 -0.987 35.8 170.4-126.6 129.2 84.9 -12.5 47.9 402 425 A Y E +D 397 0A 44 20,-3.1 2,-0.3 -2,-0.4 -5,-0.2 -0.616 16.4 168.9-136.0 72.3 82.3 -12.7 45.0 403 426 A N E -D 396 0A 2 -7,-2.9 -7,-1.7 -2,-0.2 2,-0.4 -0.612 9.8-177.2 -90.9 146.1 79.4 -10.3 45.9 404 427 A L E +DE 395 420A 0 16,-2.6 16,-3.6 -2,-0.3 2,-0.4 -0.979 3.4 176.0-139.9 132.1 76.7 -9.3 43.5 405 428 A A E +DE 394 419A 1 -11,-2.3 -11,-3.9 -2,-0.4 2,-0.3 -0.989 36.6 64.6-135.3 127.6 73.9 -6.9 44.1 406 429 A G E S-DE 393 418A 0 12,-2.3 12,-2.6 -2,-0.4 2,-0.3 -0.948 70.1 -45.9 169.0-138.7 71.3 -5.7 41.6 407 430 A F E -DE 392 417A 3 -15,-3.4 -15,-2.4 -2,-0.3 2,-0.4 -0.939 27.5-165.6-135.4 148.5 68.4 -6.7 39.3 408 431 A I E -DE 391 416A 0 8,-2.6 8,-3.1 -2,-0.3 2,-0.5 -0.996 15.2-143.7-131.2 139.5 67.5 -9.4 36.9 409 432 A T E - E 0 415A 47 -19,-2.6 6,-0.2 -2,-0.4 2,-0.1 -0.902 30.2-142.1 -99.0 125.9 64.6 -9.4 34.3 410 433 A T > - 0 0 3 4,-2.9 3,-3.0 -2,-0.5 35,-0.2 -0.325 27.1 -92.8 -89.3 171.8 63.2 -12.9 34.1 411 434 A A T 3 S+ 0 0 56 33,-3.2 34,-0.1 1,-0.3 33,-0.1 0.803 128.7 49.4 -47.9 -37.4 61.9 -15.0 31.2 412 435 A S T 3 S- 0 0 84 32,-0.4 -1,-0.3 2,-0.1 33,-0.1 0.329 121.4-108.7 -89.7 7.2 58.4 -13.8 32.0 413 436 A G S < S+ 0 0 55 -3,-3.0 2,-0.3 1,-0.3 -2,-0.1 0.624 72.2 137.8 80.6 14.5 59.6 -10.2 32.1 414 437 A Q - 0 0 45 33,-0.4 -4,-2.9 -395,-0.0 2,-0.5 -0.681 50.7-128.1 -89.1 146.8 59.3 -9.6 35.8 415 438 A R E - E 0 409A 91 -2,-0.3 -395,-2.8 -6,-0.2 2,-0.4 -0.850 24.8-171.2 -98.5 130.5 62.1 -7.7 37.5 416 439 A M E -AE 19 408A 3 -8,-3.1 -8,-2.6 -2,-0.5 2,-0.3 -0.934 14.6-142.4-118.9 141.9 63.7 -9.3 40.6 417 440 A A E -AE 18 407A 0 -399,-3.4 -399,-2.9 -2,-0.4 2,-0.3 -0.803 25.1-174.8 -97.0 147.0 66.1 -7.7 43.0 418 441 A F E -AE 17 406A 0 -12,-2.6 -12,-2.3 -2,-0.3 2,-0.4 -0.993 21.5-164.8-144.3 147.0 68.9 -9.9 44.3 419 442 A V E -AE 16 405A 0 -403,-2.6 -403,-2.3 -2,-0.3 2,-0.6 -0.980 9.5-175.5-131.9 118.8 71.8 -9.7 46.9 420 443 A Q E -AE 15 404A 0 -16,-3.6 -16,-2.6 -2,-0.4 2,-0.7 -0.961 2.2-179.6-114.6 103.9 74.5 -12.4 46.7 421 444 A Y E +A 14 0A 2 -407,-3.2 -407,-2.7 -2,-0.6 2,-0.4 -0.938 13.2 165.4-108.2 110.4 77.0 -12.1 49.5 422 445 A L E +A 13 0A 0 -2,-0.7 -20,-3.1 -409,-0.2 2,-0.2 -0.990 6.1 159.0-133.3 117.6 79.6 -14.9 49.0 423 446 A S E +A 12 0A 36 -411,-2.1 -411,-1.7 -2,-0.4 -22,-0.2 -0.757 44.4 49.6-135.1-179.3 82.9 -15.0 50.8 424 447 A G + 0 0 39 -24,-0.4 2,-2.8 -2,-0.2 -23,-0.2 0.647 60.3 150.7 57.5 16.4 85.9 -17.1 51.9 425 448 A Y + 0 0 10 -25,-2.3 -25,-0.5 1,-0.2 -1,-0.2 -0.382 14.9 135.1 -72.1 58.5 85.9 -18.5 48.4 426 449 A A 0 0 84 -2,-2.8 -1,-0.2 1,-0.8 -27,-0.0 -0.178 360.0 360.0 -82.9 36.9 89.7 -19.1 48.8 427 450 A V 0 0 110 -419,-0.1 -1,-0.8 -27,-0.0 -420,-0.0 -0.590 360.0 360.0 73.3 360.0 88.1 -22.1 47.3 428 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 429 459 A R 0 0 141 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 56.3 86.9 -20.3 39.0 430 460 A I > + 0 0 119 3,-0.1 4,-3.0 4,-0.0 5,-0.2 0.530 360.0 47.1-125.8 -55.3 84.7 -23.4 38.4 431 461 A P H > S+ 0 0 39 0, 0.0 4,-2.4 0, 0.0 5,-0.2 0.900 114.6 50.1 -56.1 -42.1 82.5 -23.9 41.5 432 462 A L H > S+ 0 0 0 2,-0.2 4,-2.8 1,-0.2 5,-0.3 0.952 112.6 46.4 -59.2 -49.4 81.6 -20.2 41.4 433 463 A V H > S+ 0 0 6 1,-0.2 4,-3.0 2,-0.2 5,-0.3 0.938 113.4 48.9 -58.9 -46.2 80.7 -20.5 37.7 434 464 A R H X S+ 0 0 115 -4,-3.0 4,-1.6 1,-0.2 -1,-0.2 0.867 112.9 47.8 -63.7 -36.6 78.7 -23.6 38.3 435 465 A F H X S+ 0 0 2 -4,-2.4 4,-2.9 -5,-0.2 -2,-0.2 0.951 116.4 41.7 -67.1 -51.0 76.9 -22.0 41.3 436 466 A E H X S+ 0 0 0 -4,-2.8 4,-2.9 2,-0.2 5,-0.5 0.848 111.3 56.2 -68.9 -36.9 76.0 -18.8 39.4 437 467 A S H X S+ 0 0 14 -4,-3.0 4,-1.8 -5,-0.3 -1,-0.2 0.944 115.8 38.5 -55.9 -50.6 75.1 -20.6 36.1 438 468 A R H X S+ 0 0 90 -4,-1.6 4,-2.7 -5,-0.3 -2,-0.2 0.937 118.4 47.8 -66.4 -48.1 72.6 -22.7 38.0 439 469 A L H X S+ 0 0 0 -4,-2.9 4,-2.2 2,-0.2 -2,-0.2 0.942 117.5 38.4 -64.1 -54.2 71.3 -19.9 40.3 440 470 A Y H X S+ 0 0 0 -4,-2.9 4,-2.5 2,-0.2 5,-0.2 0.889 115.0 54.8 -67.0 -35.5 70.8 -17.2 37.7 441 471 A K H X S+ 0 0 93 -4,-1.8 4,-2.6 -5,-0.5 5,-0.3 0.954 110.8 47.3 -58.6 -51.0 69.5 -19.7 35.1 442 472 A D H X S+ 0 0 33 -4,-2.7 4,-2.2 1,-0.2 -2,-0.2 0.902 113.1 46.8 -52.6 -51.9 66.9 -20.9 37.7 443 473 A I H < S+ 0 0 1 -4,-2.2 4,-0.3 -5,-0.2 -1,-0.2 0.897 115.1 47.3 -60.8 -41.8 65.8 -17.3 38.7 444 474 A Y H >< S+ 0 0 57 -4,-2.5 -33,-3.2 1,-0.2 3,-0.5 0.955 122.0 31.0 -69.3 -49.6 65.5 -16.2 35.0 445 475 A Q H 3< S+ 0 0 105 -4,-2.6 -2,-0.2 -5,-0.2 -1,-0.2 0.731 118.2 53.3 -87.5 -19.6 63.5 -19.2 33.7 446 476 A N T 3< 0 0 99 -4,-2.2 -1,-0.2 -5,-0.3 -2,-0.1 0.240 360.0 360.0 -97.6 10.9 61.5 -20.1 36.8 447 477 A N < 0 0 49 -3,-0.5 -33,-0.4 -4,-0.3 -37,-0.2 0.117 360.0 360.0-141.1 360.0 60.1 -16.6 37.4