==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=20-JUL-2011 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER HYDROLASE 23-OCT-08 3EZP . COMPND 2 MOLECULE: HISTONE DEACETYLASE 8; . SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; . AUTHOR D.P.DOWLING,S.L.GANTT,S.G.GATTIS,C.A.FIERKE,D.W.CHRISTIANON . 712 6 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 27604.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 489 68.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 76 10.7 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 12 1.7 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 4 0.6 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 49 6.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 100 14.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 208 29.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 10 1.4 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 2 0 1 3 0 2 3 1 2 0 2 4 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 2 2 4 0 6 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 14 A L 0 0 184 0, 0.0 111,-0.1 0, 0.0 110,-0.1 0.000 360.0 360.0 360.0 2.6 -0.5 -22.1 29.9 2 15 A V - 0 0 52 109,-0.3 112,-0.2 1,-0.1 40,-0.1 -0.845 360.0-103.3-100.3 127.2 -1.6 -19.8 27.1 3 16 A P - 0 0 21 0, 0.0 39,-2.3 0, 0.0 2,-0.4 -0.149 35.1-127.6 -47.2 129.6 -1.0 -16.0 27.5 4 17 A V E -ab 42 115A 0 110,-2.6 112,-2.8 37,-0.2 2,-0.6 -0.697 18.5-159.7 -86.0 133.5 -4.2 -14.1 28.4 5 18 A Y E -ab 43 116A 12 37,-1.8 39,-2.7 -2,-0.4 2,-1.2 -0.945 11.6-142.8-116.3 112.7 -5.1 -11.1 26.2 6 19 A I E +a 44 0A 8 110,-2.7 2,-0.3 -2,-0.6 39,-0.2 -0.640 47.1 138.8 -79.5 98.9 -7.4 -8.5 27.8 7 20 A Y + 0 0 51 -2,-1.2 3,-0.1 37,-1.0 -2,-0.1 -0.954 19.7 153.0-140.9 158.1 -9.6 -7.5 24.9 8 21 A S >> - 0 0 6 -2,-0.3 4,-2.1 37,-0.2 3,-0.7 -0.765 46.5-119.4-179.7 133.7 -13.2 -6.7 24.0 9 22 A P H 3> S+ 0 0 73 0, 0.0 4,-1.9 0, 0.0 5,-0.1 0.864 116.2 52.1 -50.5 -39.6 -14.6 -4.4 21.2 10 23 A E H 3> S+ 0 0 114 2,-0.2 4,-1.0 3,-0.2 5,-0.0 0.857 111.6 48.3 -65.8 -36.1 -16.4 -2.2 23.8 11 24 A Y H X> S+ 0 0 10 -3,-0.7 4,-2.3 2,-0.2 3,-1.2 0.990 111.9 44.4 -67.3 -65.2 -13.0 -1.9 25.7 12 25 A V H 3X S+ 0 0 15 -4,-2.1 4,-1.9 1,-0.3 14,-0.2 0.873 113.5 53.5 -49.1 -40.1 -10.7 -1.0 22.8 13 26 A S H 3< S+ 0 0 75 -4,-1.9 -1,-0.3 -5,-0.4 -2,-0.2 0.840 108.0 51.0 -64.2 -32.6 -13.4 1.4 21.6 14 27 A M H X< S+ 0 0 80 -3,-1.2 3,-1.0 -4,-1.0 -2,-0.2 0.892 110.0 48.7 -69.9 -42.6 -13.4 3.0 25.1 15 28 A C H >< S+ 0 0 6 -4,-2.3 3,-2.3 1,-0.3 -2,-0.2 0.805 97.8 67.1 -69.0 -32.1 -9.7 3.4 25.0 16 29 A D T 3< S+ 0 0 24 -4,-1.9 7,-0.9 1,-0.3 -1,-0.3 0.614 91.0 68.9 -63.6 -11.1 -9.7 5.0 21.6 17 30 A S T < + 0 0 90 -3,-1.0 2,-0.4 -4,-0.2 -1,-0.3 0.418 68.9 115.9 -87.9 -1.7 -11.5 7.8 23.3 18 31 A L < - 0 0 39 -3,-2.3 3,-0.3 3,-0.3 6,-0.2 -0.592 66.4-137.0 -71.4 125.5 -8.4 8.8 25.3 19 32 A A S S+ 0 0 70 -2,-0.4 -1,-0.1 1,-0.2 -3,-0.0 0.909 95.7 44.7 -46.1 -62.1 -7.4 12.4 24.2 20 33 A K S S+ 0 0 73 1,-0.3 -1,-0.2 113,-0.1 -2,-0.0 0.768 121.1 37.2 -59.8 -32.6 -3.7 12.0 23.9 21 34 A I S >> S- 0 0 19 -3,-0.3 3,-1.7 -6,-0.2 4,-0.5 -0.485 78.7-171.1-123.4 63.4 -3.7 8.7 22.1 22 35 A P T 34 S- 0 0 39 0, 0.0 -5,-0.1 0, 0.0 -6,-0.1 -0.335 75.5 -10.6 -59.9 124.7 -6.7 8.7 19.7 23 36 A K T 3> S+ 0 0 109 -7,-0.9 4,-2.3 -2,-0.1 5,-0.2 0.477 95.8 125.2 65.4 4.3 -7.3 5.4 18.1 24 37 A R H <> S+ 0 0 9 -3,-1.7 4,-2.3 1,-0.2 5,-0.2 0.872 70.5 56.0 -61.2 -35.9 -4.0 4.0 19.5 25 38 A A H X S+ 0 0 9 -4,-0.5 4,-2.3 2,-0.2 -1,-0.2 0.921 108.6 45.6 -62.4 -44.6 -5.9 1.2 21.1 26 39 A S H > S+ 0 0 26 -14,-0.2 4,-3.4 1,-0.2 5,-0.3 0.932 111.7 52.6 -63.2 -46.2 -7.4 0.1 17.8 27 40 A M H X S+ 0 0 10 -4,-2.3 4,-1.5 1,-0.2 5,-0.2 0.886 110.8 46.1 -56.8 -44.7 -4.1 0.4 16.0 28 41 A V H X S+ 0 0 5 -4,-2.3 4,-2.2 -5,-0.2 -1,-0.2 0.937 117.7 44.2 -64.6 -47.3 -2.3 -1.8 18.5 29 42 A H H X S+ 0 0 13 -4,-2.3 4,-3.0 -5,-0.2 5,-0.3 0.986 113.7 46.9 -61.5 -61.3 -5.1 -4.4 18.5 30 43 A S H X S+ 0 0 11 -4,-3.4 4,-1.7 1,-0.2 -1,-0.2 0.759 114.4 49.0 -54.5 -29.1 -5.6 -4.5 14.7 31 44 A L H X S+ 0 0 0 -4,-1.5 4,-0.5 -5,-0.3 -1,-0.2 0.907 112.2 46.8 -77.5 -42.1 -1.9 -4.8 14.1 32 45 A I H <>S+ 0 0 0 -4,-2.2 5,-1.9 1,-0.2 3,-0.5 0.891 118.2 44.8 -62.9 -37.1 -1.5 -7.6 16.7 33 46 A E H ><5S+ 0 0 84 -4,-3.0 3,-1.9 1,-0.2 -2,-0.2 0.793 102.5 62.3 -76.7 -31.7 -4.5 -9.2 15.1 34 47 A A H 3<5S+ 0 0 33 -4,-1.7 -1,-0.2 1,-0.3 -2,-0.2 0.625 104.7 51.2 -69.3 -11.9 -3.4 -8.7 11.5 35 48 A Y T 3<5S- 0 0 28 -4,-0.5 -1,-0.3 -3,-0.5 -2,-0.2 0.320 113.3-126.1-102.4 3.6 -0.5 -10.9 12.6 36 49 A A T X 5 + 0 0 45 -3,-1.9 3,-0.7 1,-0.1 4,-0.2 0.806 67.2 137.4 54.3 34.8 -3.0 -13.5 13.9 37 50 A L G > < + 0 0 2 -5,-1.9 3,-1.1 1,-0.2 -4,-0.2 0.690 59.4 69.6 -80.7 -19.0 -1.2 -13.4 17.3 38 51 A H G > S+ 0 0 36 -6,-0.3 3,-0.7 1,-0.2 5,-0.3 0.552 86.2 70.3 -74.3 -6.8 -4.6 -13.4 19.0 39 52 A K G < S+ 0 0 162 -3,-0.7 -1,-0.2 1,-0.2 -2,-0.2 0.742 98.5 47.2 -80.2 -24.6 -5.0 -17.0 17.8 40 53 A Q G < S+ 0 0 73 -3,-1.1 2,-0.3 -4,-0.2 -1,-0.2 0.021 105.4 77.6-104.9 27.0 -2.4 -18.2 20.2 41 54 A M S < S- 0 0 12 -3,-0.7 2,-1.3 -39,-0.1 -37,-0.2 -0.994 82.4-115.9-139.9 145.3 -3.8 -16.3 23.2 42 55 A R E -a 4 0A 127 -39,-2.3 -37,-1.8 -2,-0.3 2,-0.3 -0.629 35.1-146.5 -79.8 94.0 -6.6 -16.7 25.7 43 56 A I E -a 5 0A 74 -2,-1.3 2,-0.5 -5,-0.3 -37,-0.2 -0.480 18.7-171.4 -65.4 120.4 -8.8 -13.7 24.9 44 57 A V E -a 6 0A 26 -39,-2.7 -37,-1.0 -2,-0.3 59,-0.0 -0.967 21.5-127.7-120.2 124.5 -10.4 -12.5 28.1 45 58 A K - 0 0 130 -2,-0.5 2,-0.2 -39,-0.2 -37,-0.2 -0.441 32.1-119.7 -67.1 134.9 -13.2 -9.8 28.3 46 59 A P - 0 0 18 0, 0.0 2,-0.3 0, 0.0 53,-0.2 -0.549 18.6-138.9 -82.0 144.5 -12.3 -7.0 30.7 47 60 A K - 0 0 86 51,-0.7 55,-0.3 -2,-0.2 2,-0.3 -0.722 23.0-112.0 -97.4 145.5 -14.5 -6.3 33.7 48 61 A V - 0 0 90 -2,-0.3 47,-0.2 50,-0.1 2,-0.1 -0.597 35.1-112.6 -79.5 139.1 -15.2 -2.7 34.8 49 62 A A - 0 0 7 45,-2.3 2,-0.2 -2,-0.3 49,-0.1 -0.466 30.8-130.5 -71.2 141.0 -13.7 -1.8 38.1 50 63 A S >> - 0 0 37 -2,-0.1 4,-2.1 1,-0.1 3,-1.1 -0.488 23.4-107.0 -89.7 162.7 -16.1 -1.1 40.9 51 64 A M H 3> S+ 0 0 55 1,-0.3 4,-0.6 2,-0.2 -1,-0.1 0.719 122.8 49.7 -60.2 -21.2 -16.2 1.9 43.2 52 65 A E H 34 S+ 0 0 145 2,-0.2 -1,-0.3 1,-0.1 -3,-0.0 0.632 106.3 53.5 -92.6 -17.8 -14.9 -0.3 45.9 53 66 A E H X4 S+ 0 0 24 -3,-1.1 3,-1.2 2,-0.2 -2,-0.2 0.871 111.5 45.5 -81.6 -38.6 -12.0 -1.8 43.9 54 67 A M H >X S+ 0 0 2 -4,-2.1 4,-2.5 1,-0.3 3,-1.6 0.810 103.1 66.1 -72.2 -28.9 -10.7 1.6 43.0 55 68 A A T 3< S+ 0 0 39 -4,-0.6 -1,-0.3 -5,-0.3 -2,-0.2 0.531 78.6 82.3 -71.0 -4.2 -11.1 2.6 46.6 56 69 A T T <4 S+ 0 0 79 -3,-1.2 -1,-0.3 1,-0.1 -2,-0.2 0.604 117.9 6.6 -75.0 -8.4 -8.4 0.1 47.5 57 70 A F T <4 S+ 0 0 35 -3,-1.6 2,-0.2 1,-0.2 -2,-0.2 0.531 121.0 67.9-135.9 -44.9 -5.9 2.9 46.5 58 71 A H S < S- 0 0 4 -4,-2.5 -1,-0.2 1,-0.1 70,-0.2 -0.585 80.5-113.4 -88.8 146.5 -7.8 6.1 45.8 59 72 A T > - 0 0 44 68,-2.1 4,-3.2 -2,-0.2 5,-0.2 -0.446 19.3-124.4 -75.8 149.2 -9.6 8.2 48.4 60 73 A D H > S+ 0 0 90 1,-0.2 4,-3.2 2,-0.2 5,-0.4 0.865 113.5 57.1 -59.8 -39.0 -13.4 8.6 48.3 61 74 A A H > S+ 0 0 49 2,-0.2 4,-1.6 1,-0.2 -1,-0.2 0.939 113.3 40.7 -58.3 -45.1 -13.1 12.3 48.2 62 75 A Y H > S+ 0 0 0 2,-0.2 4,-3.2 1,-0.2 5,-0.2 0.972 117.7 45.8 -65.8 -56.7 -10.9 11.9 45.0 63 76 A L H X S+ 0 0 0 -4,-3.2 4,-1.8 1,-0.2 -2,-0.2 0.872 115.5 46.3 -54.7 -44.3 -13.0 9.2 43.4 64 77 A Q H X S+ 0 0 103 -4,-3.2 4,-2.3 -5,-0.2 -1,-0.2 0.859 114.3 48.3 -69.4 -35.0 -16.4 10.9 44.1 65 78 A H H X S+ 0 0 27 -4,-1.6 4,-2.1 -5,-0.4 -2,-0.2 0.918 110.2 51.0 -69.6 -44.1 -14.9 14.2 42.8 66 79 A L H X S+ 0 0 0 -4,-3.2 4,-1.2 1,-0.2 24,-0.4 0.883 112.0 50.3 -59.0 -37.6 -13.6 12.5 39.7 67 80 A Q H < S+ 0 0 76 -4,-1.8 4,-0.3 -5,-0.2 -2,-0.2 0.915 108.4 48.0 -68.3 -47.3 -17.1 11.1 39.3 68 81 A K H >< S+ 0 0 142 -4,-2.3 3,-1.0 1,-0.2 -1,-0.2 0.868 113.2 50.8 -62.5 -34.5 -19.0 14.4 39.6 69 82 A V H 3< S+ 0 0 26 -4,-2.1 -1,-0.2 1,-0.2 -2,-0.2 0.780 93.6 73.6 -71.7 -29.4 -16.6 15.9 37.1 70 83 A S T 3< 0 0 2 -4,-1.2 18,-1.7 -5,-0.2 -1,-0.2 0.595 360.0 360.0 -61.9 -11.6 -17.1 13.0 34.7 71 84 A Q < 0 0 156 -3,-1.0 -1,-0.1 -4,-0.3 16,-0.1 -0.725 360.0 360.0 -90.8 360.0 -20.6 14.5 33.9 72 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 73 92 A D 0 0 177 0, 0.0 3,-0.3 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 -2.8 -12.7 24.5 42.0 74 93 A S > + 0 0 42 1,-0.2 2,-2.5 2,-0.1 3,-0.9 0.866 360.0 71.1 -66.3 -40.3 -12.0 21.6 39.5 75 94 A I T 3 S+ 0 0 131 1,-0.2 -1,-0.2 3,-0.1 3,-0.2 -0.212 71.6 105.2 -74.5 49.6 -8.2 22.0 39.6 76 95 A E T 3 S+ 0 0 108 -2,-2.5 -1,-0.2 -3,-0.3 2,-0.2 0.837 79.7 35.8 -96.6 -45.0 -8.4 20.5 43.1 77 96 A Y S < S- 0 0 42 -3,-0.9 53,-2.7 -15,-0.1 -1,-0.1 -0.333 131.2 -77.3-108.4 50.4 -7.1 17.0 42.6 78 97 A G S >S+ 0 0 27 51,-0.2 2,-1.6 -3,-0.2 5,-0.6 0.644 88.4 141.9 67.8 14.0 -4.5 17.7 39.9 79 98 A L T 5 + 0 0 4 -5,-0.5 6,-0.2 3,-0.1 -1,-0.2 -0.363 39.5 99.8 -85.3 58.6 -7.3 18.0 37.3 80 99 A G T 5S- 0 0 21 -2,-1.6 5,-0.1 4,-0.2 -4,-0.0 0.309 88.7 -23.4-110.0-125.4 -5.7 20.9 35.5 81 100 A Y T 5S+ 0 0 74 1,-0.1 -2,-0.1 3,-0.1 566,-0.0 0.917 137.4 36.0 -58.9 -51.2 -3.7 21.3 32.2 82 101 A N T 5S+ 0 0 53 1,-0.3 -1,-0.1 -4,-0.1 -3,-0.1 0.973 128.3 33.6 -68.8 -57.9 -2.3 17.7 32.1 83 102 A C S - 0 0 69 1,-0.1 3,-1.7 -2,-0.1 2,-0.3 -0.021 35.1-105.6 -44.4 132.3 -13.0 15.7 30.5 87 106 A E T 3 S+ 0 0 161 1,-0.3 -16,-0.2 2,-0.1 -17,-0.2 -0.438 104.3 14.4 -63.6 118.9 -16.6 14.5 30.4 88 107 A G T 3 S+ 0 0 31 -18,-1.7 -1,-0.3 -2,-0.3 3,-0.1 0.590 81.3 126.3 93.8 10.9 -16.6 10.7 30.9 89 108 A I < + 0 0 20 -3,-1.7 5,-0.3 1,-0.2 -2,-0.1 0.864 69.7 61.2 -69.1 -35.3 -13.1 10.2 32.3 90 109 A F 0 0 26 -24,-0.4 4,-1.5 -4,-0.3 -1,-0.2 0.886 360.0 360.0 -57.2 -38.2 -14.4 8.5 35.4 91 110 A D 0 0 87 2,-0.2 4,-1.5 3,-0.1 -1,-0.2 0.816 360.0 360.0 -74.2 360.0 -15.9 5.8 33.1 92 ! 0 0 0 0, 0.0 0, 0.0 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 360.0 0.0 0.0 0.0 93 112 A A > 0 0 10 0, 0.0 4,-2.8 0, 0.0 5,-0.2 0.000 360.0 360.0 360.0 -34.0 -10.5 5.1 34.1 94 113 A A H > + 0 0 6 -4,-1.5 4,-2.4 -5,-0.3 -45,-2.3 0.890 360.0 48.7 -68.0 -37.9 -12.9 2.5 35.6 95 114 A A H > S+ 0 0 10 -4,-1.5 4,-0.8 -47,-0.2 -1,-0.2 0.918 116.7 40.9 -66.8 -46.4 -12.7 0.5 32.4 96 115 A I H > S+ 0 0 7 2,-0.2 4,-0.8 1,-0.2 -2,-0.2 0.870 116.0 50.3 -71.0 -38.9 -8.9 0.6 32.2 97 116 A G H >X S+ 0 0 1 -4,-2.8 4,-2.0 1,-0.2 3,-1.0 0.940 113.0 45.0 -64.7 -47.2 -8.5 0.0 36.0 98 117 A G H 3X S+ 0 0 0 -4,-2.4 4,-2.2 1,-0.3 -51,-0.7 0.698 104.5 64.9 -69.7 -18.4 -10.8 -3.0 35.9 99 118 A A H 3X S+ 0 0 0 -4,-0.8 4,-0.9 2,-0.2 -1,-0.3 0.766 107.9 40.3 -74.2 -24.9 -9.0 -4.2 32.8 100 119 A T H X S+ 0 0 0 -4,-2.5 4,-1.3 1,-0.2 3,-0.6 0.915 102.7 56.9 -65.5 -42.9 -4.3 -9.7 37.7 105 124 A Q H 3< S+ 0 0 53 -4,-2.2 3,-0.3 1,-0.2 -1,-0.2 0.871 101.2 56.1 -56.2 -42.3 -7.0 -12.2 38.8 106 125 A C H ><>S+ 0 0 5 -4,-1.2 3,-1.2 1,-0.2 5,-1.0 0.824 103.5 55.4 -60.9 -33.6 -6.1 -14.6 36.0 107 126 A L H X<5S+ 0 0 9 -4,-0.9 3,-0.8 -3,-0.6 -1,-0.2 0.866 108.5 47.5 -67.6 -35.9 -2.5 -14.7 37.3 108 127 A I T 3<5S+ 0 0 10 -4,-1.3 -1,-0.3 -3,-0.3 -2,-0.2 -0.014 110.0 55.2 -94.1 28.4 -3.7 -15.7 40.7 109 128 A D T < 5S- 0 0 91 -3,-1.2 -1,-0.2 3,-0.3 -2,-0.2 0.236 103.9-123.9-135.8 1.0 -5.9 -18.4 39.2 110 129 A G T < 5S+ 0 0 65 -3,-0.8 -3,-0.2 2,-0.2 -4,-0.1 0.545 74.6 130.6 63.1 3.3 -3.2 -20.2 37.2 111 130 A M S + c 0 282A 1 164,-2.5 3,-2.1 -2,-0.5 166,-1.1 -0.649 4.4 175.7-140.4 78.9 -3.4 -5.2 29.0 118 137 A W T 3 S+ 0 0 13 1,-0.3 166,-0.5 164,-0.3 164,-0.1 0.712 78.0 62.9 -57.0 -24.3 -1.7 -2.8 26.5 119 138 A S T 3 S+ 0 0 20 164,-0.1 -1,-0.3 163,-0.1 2,-0.1 0.538 98.1 71.6 -83.1 -2.3 -4.2 -0.1 27.3 120 139 A G < + 0 0 1 -3,-2.1 163,-0.5 161,-0.2 3,-0.1 -0.335 40.6 101.8-100.3-174.8 -3.0 0.1 30.9 121 140 A G + 0 0 1 161,-0.2 2,-2.1 1,-0.1 164,-0.2 0.638 33.6 162.1 110.2 23.5 0.1 1.3 32.6 122 141 A W > + 0 0 25 1,-0.2 3,-0.5 162,-0.1 17,-0.3 -0.504 10.5 165.3 -75.6 79.9 -1.1 4.7 33.9 123 142 A H T 3 + 0 0 5 -2,-2.1 43,-1.0 1,-0.2 42,-0.6 0.498 51.8 69.0 -81.7 -4.7 1.7 5.1 36.4 124 143 A H T 3 + 0 0 10 7,-0.2 -1,-0.2 41,-0.2 8,-0.1 0.717 67.6 113.5 -89.1 -17.8 1.6 8.7 37.5 125 144 A A < - 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