==== Secondary Structure Definition by the program DSSP, updated CMBI version by ElmK / April 1,2000 ==== DATE=3-MAY-2013 . REFERENCE W. KABSCH AND C.SANDER, BIOPOLYMERS 22 (1983) 2577-2637 . HEADER TRANSFERASE/TRANSFERASE INHIBITOR 02-MAY-12 4EZ8 . COMPND 2 MOLECULE: THYMIDYLATE SYNTHASE; . SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; . AUTHOR A.DOWIERCIAL,A.JARMULA,W.RYPNIEWSKI,P.WILK,B.KIERDASZUK,K.BA . 288 2 0 0 0 TOTAL NUMBER OF RESIDUES, NUMBER OF CHAINS, NUMBER OF SS-BRIDGES(TOTAL,INTRACHAIN,INTERCHAIN) . 13231.0 ACCESSIBLE SURFACE OF PROTEIN (ANGSTROM**2) . 207 71.9 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(J) , SAME NUMBER PER 100 RESIDUES . 13 4.5 TOTAL NUMBER OF HYDROGEN BONDS IN PARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 40 13.9 TOTAL NUMBER OF HYDROGEN BONDS IN ANTIPARALLEL BRIDGES, SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-5), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-4), SAME NUMBER PER 100 RESIDUES . 1 0.3 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-3), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-2), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I-1), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+0), SAME NUMBER PER 100 RESIDUES . 0 0.0 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+1), SAME NUMBER PER 100 RESIDUES . 35 12.2 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+2), SAME NUMBER PER 100 RESIDUES . 33 11.5 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+3), SAME NUMBER PER 100 RESIDUES . 71 24.7 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+4), SAME NUMBER PER 100 RESIDUES . 6 2.1 TOTAL NUMBER OF HYDROGEN BONDS OF TYPE O(I)-->H-N(I+5), SAME NUMBER PER 100 RESIDUES . 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 *** HISTOGRAMS OF *** . 0 0 0 0 1 1 1 1 0 0 1 1 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 RESIDUES PER ALPHA HELIX . 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 PARALLEL BRIDGES PER LADDER . 2 0 2 1 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 ANTIPARALLEL BRIDGES PER LADDER . 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 LADDERS PER SHEET . # RESIDUE AA STRUCTURE BP1 BP2 ACC N-H-->O O-->H-N N-H-->O O-->H-N TCO KAPPA ALPHA PHI PSI X-CA Y-CA Z-CA 1 21 A R 0 0 282 0, 0.0 2,-0.1 0, 0.0 0, 0.0 0.000 360.0 360.0 360.0 19.1 45.6 -12.0 -5.7 2 22 A H > - 0 0 44 1,-0.1 3,-1.6 2,-0.1 4,-0.3 -0.393 360.0-132.4 -62.6 134.8 42.9 -14.6 -4.8 3 23 A G T >> S+ 0 0 14 1,-0.3 3,-1.6 2,-0.2 4,-0.6 0.800 102.4 67.7 -60.6 -30.6 39.5 -13.0 -4.3 4 24 A E H 3> S+ 0 0 0 1,-0.3 4,-2.2 2,-0.2 3,-0.4 0.759 82.7 75.4 -62.2 -26.1 38.9 -14.9 -1.1 5 25 A L H <> S+ 0 0 44 -3,-1.6 4,-2.6 1,-0.2 -1,-0.3 0.805 87.0 62.2 -57.6 -29.4 41.7 -12.8 0.5 6 26 A Q H <> S+ 0 0 63 -3,-1.6 4,-2.0 -4,-0.3 -1,-0.2 0.945 106.0 43.7 -62.8 -46.4 39.3 -9.9 0.7 7 27 A Y H X S+ 0 0 0 -4,-0.6 4,-2.3 -3,-0.4 -2,-0.2 0.928 114.6 49.6 -60.0 -49.8 36.9 -11.9 3.0 8 28 A L H X S+ 0 0 11 -4,-2.2 4,-2.5 1,-0.2 -2,-0.2 0.906 111.1 49.9 -59.7 -41.0 39.8 -13.2 5.1 9 29 A R H X S+ 0 0 156 -4,-2.6 4,-2.4 2,-0.2 -1,-0.2 0.862 107.6 53.7 -68.8 -31.8 41.2 -9.6 5.4 10 30 A Q H X S+ 0 0 12 -4,-2.0 4,-2.3 -5,-0.2 -2,-0.2 0.930 110.0 48.0 -65.1 -43.6 37.8 -8.3 6.5 11 31 A V H X S+ 0 0 1 -4,-2.3 4,-2.5 1,-0.2 -2,-0.2 0.939 112.8 48.0 -58.6 -49.6 37.7 -10.9 9.2 12 32 A E H X S+ 0 0 89 -4,-2.5 4,-2.0 1,-0.2 5,-0.2 0.892 110.0 53.0 -57.2 -43.1 41.2 -10.0 10.3 13 33 A H H X>S+ 0 0 86 -4,-2.4 4,-3.2 1,-0.2 5,-0.6 0.921 110.4 46.6 -61.8 -44.1 40.3 -6.3 10.3 14 34 A I H X5S+ 0 0 0 -4,-2.3 4,-1.6 3,-0.2 -2,-0.2 0.926 112.3 50.9 -64.0 -42.6 37.3 -6.9 12.6 15 35 A L H <5S+ 0 0 21 -4,-2.5 -1,-0.2 -5,-0.2 -2,-0.2 0.832 122.3 31.9 -63.6 -33.2 39.4 -9.1 14.9 16 36 A R H <5S+ 0 0 194 -4,-2.0 -2,-0.2 -5,-0.2 -1,-0.2 0.834 137.3 16.6 -91.8 -38.9 42.1 -6.5 15.2 17 37 A C H <5S+ 0 0 78 -4,-3.2 -3,-0.2 -5,-0.2 -2,-0.2 0.474 91.5 113.2-121.8 -5.3 40.2 -3.2 14.9 18 38 A G << - 0 0 20 -4,-1.6 2,-0.3 -5,-0.6 14,-0.2 -0.267 61.2-123.6 -65.5 158.2 36.6 -3.9 15.5 19 39 A F E -A 31 0A 166 12,-2.6 12,-2.3 1,-0.0 2,-0.2 -0.751 25.5-104.7 -97.6 144.1 34.8 -2.6 18.5 20 40 A K E +A 30 0A 111 -2,-0.3 2,-0.3 10,-0.2 10,-0.2 -0.496 46.2 179.2 -60.2 135.3 33.0 -4.6 21.1 21 41 A K E -A 29 0A 105 8,-2.5 8,-1.8 -2,-0.2 2,-0.0 -0.962 23.7-134.4-147.7 121.8 29.2 -4.2 20.4 22 42 A E - 0 0 131 -2,-0.3 2,-0.3 6,-0.2 3,-0.0 -0.315 31.7-156.8 -65.5 159.7 26.4 -5.8 22.3 23 43 A D > - 0 0 38 1,-0.1 3,-2.0 -2,-0.0 5,-0.0 -0.942 31.1 -98.9-144.2 167.7 23.6 -7.2 20.2 24 44 A R T 3 S+ 0 0 158 -2,-0.3 -1,-0.1 1,-0.3 -2,-0.0 0.771 118.3 52.8 -48.8 -42.9 20.0 -8.3 19.9 25 45 A T T 3 S- 0 0 25 261,-0.1 -1,-0.3 1,-0.0 262,-0.2 0.561 107.1-123.2 -78.0 -11.3 20.8 -12.0 20.5 26 46 A G S < S+ 0 0 61 -3,-2.0 -2,-0.1 260,-0.1 -1,-0.0 0.598 83.7 109.6 79.8 9.2 22.7 -11.3 23.7 27 47 A T S S- 0 0 43 1,-0.0 206,-0.1 206,-0.0 -3,-0.1 0.837 71.8-133.1 -82.5 -41.4 25.8 -13.0 22.3 28 48 A G - 0 0 0 204,-0.1 205,-2.2 205,-0.1 2,-0.3 0.163 20.6-147.8 90.0 149.2 28.1 -10.0 21.8 29 49 A T E -AB 21 232A 3 -8,-1.8 -8,-2.5 203,-0.3 2,-0.4 -0.940 21.8-128.1-140.6 161.2 30.2 -9.1 18.8 30 50 A L E -AB 20 231A 33 201,-2.2 201,-2.7 -2,-0.3 2,-0.4 -0.961 49.3-171.6-102.2 136.5 33.3 -7.4 17.5 31 51 A S E -AB 19 230A 12 -12,-2.3 -12,-2.6 -2,-0.4 2,-0.3 -0.969 31.0-174.1-143.4 143.8 32.0 -5.0 14.9 32 52 A V E - B 0 229A 24 197,-2.6 197,-2.7 -2,-0.4 2,-0.6 -0.994 22.9-139.8-128.8 138.7 33.0 -2.6 12.1 33 53 A F E S+ B 0 228A 164 -2,-0.3 195,-0.2 195,-0.2 194,-0.1 -0.890 73.5 20.1-103.4 118.1 30.5 -0.3 10.3 34 54 A G E + 0 0 46 193,-2.4 2,-0.3 -2,-0.6 193,-0.2 0.748 64.5 160.9 95.0 102.9 31.0 -0.0 6.5 35 55 A M E - B 0 226A 25 191,-1.4 191,-2.5 -3,-0.1 2,-0.3 -0.958 14.3-167.0-140.9 161.7 33.0 -2.5 4.5 36 56 A Q E + B 0 225A 120 -2,-0.3 2,-0.3 189,-0.2 189,-0.2 -0.970 6.3 176.7-151.4 138.3 33.2 -3.3 0.8 37 57 A A E - B 0 224A 4 187,-2.1 187,-2.6 -2,-0.3 2,-0.5 -0.937 18.2-144.5-134.7 156.6 34.7 -6.2 -1.3 38 58 A R E - B 0 223A 127 -2,-0.3 2,-0.6 185,-0.2 185,-0.2 -0.972 12.0-168.0-127.2 114.3 34.7 -7.0 -5.0 39 59 A Y E - B 0 222A 1 183,-3.1 183,-2.7 -2,-0.5 2,-0.1 -0.896 19.8-133.0-104.4 114.7 34.5 -10.6 -6.2 40 60 A S E - B 0 221A 38 -2,-0.6 181,-0.2 181,-0.2 180,-0.1 -0.439 16.0-170.4 -62.8 141.8 35.2 -11.2 -9.8 41 61 A L + 0 0 0 179,-2.9 2,-0.9 -2,-0.1 3,-0.3 0.192 47.3 122.2-109.1 7.3 32.7 -13.5 -11.5 42 62 A R S S- 0 0 85 178,-0.3 3,-0.1 1,-0.2 178,-0.1 -0.659 95.8 -26.1 -86.1 103.6 34.8 -13.8 -14.7 43 63 A D S S+ 0 0 137 -2,-0.9 2,-0.3 1,-0.1 -1,-0.2 0.665 131.4 65.3 64.8 22.4 35.6 -17.5 -15.3 44 64 A E S S- 0 0 59 -3,-0.3 208,-0.2 208,-0.1 -1,-0.1 -0.967 70.2-135.4-163.9 166.8 35.3 -18.3 -11.7 45 65 A F - 0 0 0 206,-2.5 2,-2.4 -2,-0.3 -4,-0.1 -0.995 22.6-127.0-132.5 124.6 32.7 -18.4 -8.9 46 66 A P + 0 0 0 0, 0.0 2,-0.7 0, 0.0 159,-0.1 -0.339 49.9 147.4 -83.9 66.9 33.4 -17.1 -5.4 47 67 A L - 0 0 0 -2,-2.4 -2,-0.1 204,-0.1 -43,-0.1 -0.888 56.7-112.6 -93.1 111.7 32.5 -20.1 -3.3 48 68 A L - 0 0 0 -2,-0.7 5,-0.5 150,-0.3 3,-0.0 -0.145 29.2-168.5 -58.7 143.5 34.8 -19.8 -0.3 49 69 A T S S+ 0 0 0 199,-0.2 229,-2.9 1,-0.1 -1,-0.1 0.561 71.8 79.8-105.8 -16.1 37.5 -22.5 -0.0 50 70 A T S S+ 0 0 0 227,-0.2 2,-0.3 1,-0.1 -1,-0.1 0.615 113.3 12.6 -78.1 -5.8 38.9 -21.9 3.4 51 71 A K S S- 0 0 14 -3,-0.0 2,-0.5 229,-0.0 229,-0.2 -0.953 95.8 -95.8-151.0 154.8 35.9 -23.8 4.8 52 72 A R - 0 0 125 226,-0.5 2,-0.3 -2,-0.3 229,-0.3 -0.613 41.0-149.8 -71.4 123.0 33.3 -26.0 2.9 53 73 A V - 0 0 10 -5,-0.5 2,-2.2 -2,-0.5 3,-0.2 -0.733 23.4-111.1 -94.3 146.5 30.2 -23.8 2.2 54 74 A F >> + 0 0 74 -2,-0.3 4,-1.8 1,-0.2 3,-0.6 -0.422 45.3 169.2 -79.1 73.1 26.8 -25.3 2.0 55 75 A W H 3> S+ 0 0 40 -2,-2.2 4,-2.6 1,-0.3 5,-0.3 0.869 72.2 59.0 -60.5 -39.4 26.3 -24.9 -1.7 56 76 A K H 3> S+ 0 0 106 1,-0.2 4,-2.6 2,-0.2 -1,-0.3 0.902 108.3 47.7 -55.4 -43.8 23.1 -27.1 -1.8 57 77 A G H <> S+ 0 0 0 -3,-0.6 4,-2.5 2,-0.2 5,-0.2 0.898 110.1 51.9 -62.1 -43.3 21.6 -24.7 0.7 58 78 A V H X S+ 0 0 0 -4,-1.8 4,-2.0 2,-0.2 -2,-0.2 0.948 114.4 42.2 -57.8 -51.0 22.6 -21.7 -1.4 59 79 A L H X S+ 0 0 5 -4,-2.6 4,-2.3 2,-0.2 5,-0.2 0.939 116.2 46.1 -67.3 -48.9 21.1 -23.0 -4.5 60 80 A E H X S+ 0 0 28 -4,-2.6 4,-2.1 -5,-0.3 -1,-0.2 0.912 111.4 53.5 -62.7 -39.5 17.9 -24.3 -3.1 61 81 A E H X S+ 0 0 5 -4,-2.5 4,-2.6 -5,-0.2 -1,-0.2 0.942 109.4 47.5 -59.7 -45.0 17.3 -21.1 -1.1 62 82 A L H X S+ 0 0 0 -4,-2.0 4,-2.4 -5,-0.2 -1,-0.2 0.925 110.5 50.8 -66.2 -40.6 17.7 -19.0 -4.2 63 83 A L H X S+ 0 0 7 -4,-2.3 4,-1.6 1,-0.2 -1,-0.2 0.891 110.4 51.5 -60.6 -36.3 15.3 -21.2 -6.2 64 84 A W H <>S+ 0 0 15 -4,-2.1 5,-1.9 2,-0.2 -2,-0.2 0.900 108.7 49.8 -68.0 -44.2 12.8 -20.9 -3.3 65 85 A F H ><5S+ 0 0 3 -4,-2.6 3,-2.0 1,-0.2 -2,-0.2 0.916 107.5 54.9 -55.3 -44.5 13.1 -17.1 -3.3 66 86 A I H 3<5S+ 0 0 7 -4,-2.4 -2,-0.2 1,-0.3 -1,-0.2 0.884 101.8 57.4 -64.2 -35.5 12.5 -17.0 -7.0 67 87 A K T 3<5S- 0 0 154 -4,-1.6 -1,-0.3 -5,-0.2 -2,-0.2 0.466 117.8-115.8 -67.5 -4.5 9.3 -19.0 -6.5 68 88 A G T < 5 + 0 0 16 -3,-2.0 -3,-0.2 1,-0.2 -2,-0.1 0.583 59.0 161.9 81.6 12.0 8.2 -16.2 -4.2 69 89 A S < + 0 0 11 -5,-1.9 41,-0.6 41,-0.2 -1,-0.2 -0.398 31.5 171.0 -76.8 144.4 8.1 -18.3 -1.1 70 90 A T + 0 0 3 53,-0.3 35,-2.4 40,-0.2 2,-0.7 0.004 54.3 107.0-124.4 22.9 8.1 -17.1 2.4 71 91 A N B >> -F 104 0B 20 33,-0.2 3,-1.5 52,-0.2 4,-0.7 -0.880 52.3-165.1-109.9 101.8 7.4 -20.6 3.8 72 92 A A H >> S+ 0 0 1 31,-2.7 4,-2.8 -2,-0.7 3,-0.6 0.769 86.3 68.2 -56.0 -29.5 10.4 -22.2 5.5 73 93 A K H 3> S+ 0 0 109 1,-0.2 4,-1.2 2,-0.2 -1,-0.3 0.801 93.8 57.1 -63.0 -27.6 8.7 -25.6 5.3 74 94 A E H <4 S+ 0 0 100 -3,-1.5 -1,-0.2 2,-0.2 -2,-0.2 0.797 113.8 38.6 -71.1 -31.8 8.9 -25.6 1.6 75 95 A L H X<>S+ 0 0 2 -4,-0.7 3,-2.0 -3,-0.6 5,-1.0 0.828 106.8 65.1 -84.0 -37.2 12.7 -25.2 1.8 76 96 A S H ><5S+ 0 0 31 -4,-2.8 3,-2.2 1,-0.3 4,-0.3 0.850 92.9 61.1 -55.4 -41.3 13.2 -27.5 4.8 77 97 A S T 3<5S+ 0 0 99 -4,-1.2 -1,-0.3 1,-0.3 -2,-0.1 0.651 93.8 64.9 -65.8 -16.0 12.0 -30.6 2.9 78 98 A K T < 5S- 0 0 90 -3,-2.0 -1,-0.3 2,-0.2 -2,-0.2 0.429 125.9-102.1 -75.3 -2.9 15.0 -30.1 0.5 79 99 A G T < 5S+ 0 0 23 -3,-2.2 2,-0.6 1,-0.2 -3,-0.2 0.736 89.8 124.5 79.5 24.3 17.2 -30.8 3.5 80 100 A V < + 0 0 0 -5,-1.0 3,-0.3 -4,-0.3 -2,-0.2 -0.929 28.9 169.1-123.1 99.5 17.9 -27.0 3.8 81 101 A R >> + 0 0 165 -2,-0.6 3,-1.7 1,-0.2 4,-0.5 0.247 36.4 116.6-101.0 12.0 17.0 -26.1 7.3 82 102 A I T 34 S+ 0 0 11 1,-0.3 4,-0.2 2,-0.1 -1,-0.2 0.690 83.4 36.6 -60.9 -27.6 18.5 -22.5 7.4 83 103 A W T 3> S+ 0 0 20 -3,-0.3 4,-1.2 -11,-0.2 -1,-0.3 0.376 90.5 95.9-103.4 2.2 15.2 -20.7 7.9 84 104 A D T <4 S+ 0 0 44 -3,-1.7 4,-0.4 1,-0.2 3,-0.3 0.889 82.2 49.9 -66.0 -40.8 13.5 -23.2 10.2 85 105 A A T >< S+ 0 0 43 -4,-0.5 3,-1.2 1,-0.2 6,-0.3 0.916 108.9 53.2 -61.9 -44.1 14.4 -21.6 13.5 86 106 A N T 34 S+ 0 0 18 1,-0.3 -1,-0.2 -4,-0.2 -2,-0.2 0.760 115.0 41.3 -66.5 -25.6 13.1 -18.2 12.3 87 107 A G T 3< S+ 0 0 2 -4,-1.2 16,-2.8 -3,-0.3 17,-0.4 0.367 88.5 124.7-101.9 9.0 9.8 -19.9 11.4 88 108 A S S <> S- 0 0 35 -3,-1.2 4,-3.1 -4,-0.4 5,-0.3 -0.261 71.8-114.6 -73.6 153.0 9.4 -22.1 14.4 89 109 A R H > S+ 0 0 66 1,-0.2 4,-2.7 2,-0.2 5,-0.2 0.910 115.3 46.1 -48.4 -52.3 6.4 -22.0 16.7 90 110 A D H > S+ 0 0 130 2,-0.2 4,-1.9 1,-0.2 -1,-0.2 0.904 113.8 46.8 -67.3 -40.1 8.3 -20.7 19.6 91 111 A F H > S+ 0 0 42 -6,-0.3 4,-0.9 2,-0.2 -2,-0.2 0.937 114.3 48.4 -64.4 -50.6 10.2 -18.0 17.7 92 112 A L H ><>S+ 0 0 0 -4,-3.1 5,-2.7 1,-0.2 3,-1.1 0.934 111.1 49.7 -53.6 -47.7 7.1 -16.8 16.0 93 113 A D H ><5S+ 0 0 64 -4,-2.7 3,-1.8 -5,-0.3 5,-0.2 0.901 103.6 61.0 -60.4 -35.2 5.2 -16.7 19.3 94 114 A S H 3<5S+ 0 0 83 -4,-1.9 -1,-0.2 1,-0.3 -2,-0.2 0.772 106.7 46.0 -63.4 -21.9 8.1 -14.7 20.8 95 115 A L T <<5S- 0 0 75 -3,-1.1 -1,-0.3 -4,-0.9 -2,-0.2 0.332 126.4-100.6-102.3 6.4 7.5 -11.9 18.2 96 116 A G T < 5S+ 0 0 59 -3,-1.8 2,-0.7 -4,-0.3 3,-0.3 0.568 85.4 126.7 85.8 14.1 3.7 -12.0 18.8 97 117 A F > < + 0 0 31 -5,-2.7 3,-1.1 1,-0.2 -4,-0.2 -0.302 16.5 138.1-102.2 53.8 2.8 -14.1 15.8 98 118 A S T 3 + 0 0 87 -2,-0.7 -1,-0.2 1,-0.2 -5,-0.1 0.795 68.8 58.5 -73.9 -20.7 0.8 -16.8 17.5 99 119 A A T 3 S+ 0 0 100 -3,-0.3 -1,-0.2 -7,-0.1 2,-0.2 0.694 89.3 98.7 -74.3 -15.0 -1.9 -16.8 14.8 100 120 A R S < S- 0 0 20 -3,-1.1 2,-0.1 1,-0.1 3,-0.1 -0.472 77.3-117.5 -81.3 141.4 0.7 -17.6 12.3 101 121 A Q > - 0 0 81 -2,-0.2 3,-1.9 1,-0.1 -1,-0.1 -0.416 43.4 -89.9 -68.9 149.6 1.4 -21.1 10.9 102 122 A E T 3 S+ 0 0 87 1,-0.2 -14,-0.2 -2,-0.1 -29,-0.1 -0.327 115.3 31.1 -59.9 140.2 4.8 -22.6 11.5 103 123 A G T 3 S+ 0 0 1 -16,-2.8 -31,-2.7 1,-0.2 2,-1.1 0.202 80.3 129.8 96.9 -16.9 7.1 -21.8 8.7 104 124 A D B < +F 71 0B 0 -3,-1.9 -1,-0.2 -17,-0.4 -33,-0.2 -0.607 30.4 179.6 -82.1 99.3 5.5 -18.4 7.9 105 125 A L - 0 0 1 -35,-2.4 60,-2.5 -2,-1.1 61,-0.5 0.523 39.2-124.1 -76.1 -6.2 8.5 -16.0 7.8 106 126 A G - 0 0 0 -36,-0.3 2,-2.4 58,-0.2 -1,-0.3 -0.391 59.9 -23.3 84.9-169.2 6.3 -13.0 7.0 107 127 A P S S+ 0 0 0 0, 0.0 57,-0.1 0, 0.0 50,-0.1 -0.374 92.0 138.2 -83.0 68.6 6.7 -10.7 4.0 108 128 A V >> - 0 0 11 -2,-2.4 4,-2.6 55,-0.1 3,-0.8 0.078 66.5 -42.3 -97.4-156.2 10.4 -11.3 3.3 109 129 A Y H 3> S+ 0 0 6 1,-0.3 4,-3.0 2,-0.2 5,-0.3 0.827 130.2 49.8 -49.4 -52.8 12.4 -11.8 0.1 110 130 A G H 3> S+ 0 0 1 -41,-0.6 4,-1.1 1,-0.2 -1,-0.3 0.910 118.9 40.5 -56.2 -41.2 10.2 -14.1 -1.9 111 131 A F 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